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addition of published article link
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app.R

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@@ -272,9 +272,9 @@ ui <- fluidPage(
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p("Prepared by",
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a("Emma Rand", href = "mailto:[email protected]"),
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"in support of:"),
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h3(a("Wilson, A.J.,", href = "mailto:[email protected]"),
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"Rand, E., Webster, A.J. & Genever, P.G. (2021)", em( "Characterization of mesenchymal stromal cells in clinical trial reports: analysis of published descriptors."),
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"Manuscript submitted"),
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h3(a("Wilson, A. J.,", href = "mailto:[email protected]"),
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"Rand, E., Webster, A. J., & Genever, P. G. (2021). Characterisation of mesenchymal stromal cells in clinical trial reports: analysis of published descriptors.", em("Stem cell research & therapy, 12"),"(1), 360.",
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a("https://doi.org/10.1186/s13287-021-02435-1", href = "https://doi.org/10.1186/s13287-021-02435-1")),
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h3("Abstract"),
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p(strong("Background:"),"Mesenchymal stem or stromal cells are the most widely used cell therapy to date. They are heterogeneous, with variations in growth potential, differentiation capacity and protein expression profile depending on tissue source and production process. Nomenclature and defining characteristics have been debated for almost 20 years, yet the generic term “MSC” is used to cover a wide range of cellular phenotypes. Against a documented lack of definition of cellular populations used in clinical trials, our study evaluated the extent of characterization of the cellular population or study drug."),
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p(strong("Methods:"),"A literature search of clinical trials involving mesenchymal stem/stromal cells was refined to 84 papers upon application of pre-defined inclusion/exclusion criteria. Data were extracted covering background trial information including location, phase, indication, tissue source, and details of clinical cell population characterisation (expression of surface markers, viability, differentiation assays and potency/functionality assays). Descriptive statistics were applied, and tests of association between groups were explored using Fisher's Exact Test for Count Data with simulated p-value."),

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