diff --git a/change-beta/@azure-communication-react-ae4dd794-8396-42ec-b246-234e9dfc7214.json b/change-beta/@azure-communication-react-ae4dd794-8396-42ec-b246-234e9dfc7214.json
new file mode 100644
index 00000000000..5faa96bbf49
--- /dev/null
+++ b/change-beta/@azure-communication-react-ae4dd794-8396-42ec-b246-234e9dfc7214.json
@@ -0,0 +1,9 @@
+{
+  "type": "patch",
+  "area": "fix",
+  "workstream": "Breakout rooms",
+  "comment": "Ensure createChatAdapterCallback is set for AzureCommunicationCallWithChatAdapter in createAzureCommunicationCallWithChatAdapterFromClients so that a new ChatAdapter can be created when joining a breakout room",
+  "packageName": "@azure/communication-react",
+  "email": "79475487+mgamis-msft@users.noreply.github.com",
+  "dependentChangeType": "patch"
+}
diff --git a/change/@azure-communication-react-ae4dd794-8396-42ec-b246-234e9dfc7214.json b/change/@azure-communication-react-ae4dd794-8396-42ec-b246-234e9dfc7214.json
new file mode 100644
index 00000000000..5faa96bbf49
--- /dev/null
+++ b/change/@azure-communication-react-ae4dd794-8396-42ec-b246-234e9dfc7214.json
@@ -0,0 +1,9 @@
+{
+  "type": "patch",
+  "area": "fix",
+  "workstream": "Breakout rooms",
+  "comment": "Ensure createChatAdapterCallback is set for AzureCommunicationCallWithChatAdapter in createAzureCommunicationCallWithChatAdapterFromClients so that a new ChatAdapter can be created when joining a breakout room",
+  "packageName": "@azure/communication-react",
+  "email": "79475487+mgamis-msft@users.noreply.github.com",
+  "dependentChangeType": "patch"
+}
diff --git a/packages/react-composites/src/composites/CallWithChatComposite/adapter/AzureCommunicationCallWithChatAdapter.ts b/packages/react-composites/src/composites/CallWithChatComposite/adapter/AzureCommunicationCallWithChatAdapter.ts
index 7ffd3095eca..244634fd227 100644
--- a/packages/react-composites/src/composites/CallWithChatComposite/adapter/AzureCommunicationCallWithChatAdapter.ts
+++ b/packages/react-composites/src/composites/CallWithChatComposite/adapter/AzureCommunicationCallWithChatAdapter.ts
@@ -1471,7 +1471,12 @@ export const createAzureCommunicationCallWithChatAdapterFromClients = async ({
     callAdapterOptions
   );
   const chatAdapter = await createAzureCommunicationChatAdapterFromClient(chatClient, chatThreadClient);
-  return new AzureCommunicationCallWithChatAdapter(callAdapter, chatAdapter);
+  const callWithChatAdapter = new AzureCommunicationCallWithChatAdapter(callAdapter, chatAdapter);
+  /* @conditional-compile-remove(breakout-rooms) */
+  callWithChatAdapter.setCreateChatAdapterCallback((threadId: string) =>
+    createAzureCommunicationChatAdapterFromClient(chatClient, chatClient.getChatThreadClient(threadId))
+  );
+  return callWithChatAdapter;
 };
 
 /**