diff --git a/comp/logs-library/pipeline/nodeless.go b/comp/logs-library/pipeline/nodeless.go
new file mode 100644
index 000000000000..34e0e1a7885c
--- /dev/null
+++ b/comp/logs-library/pipeline/nodeless.go
@@ -0,0 +1,46 @@
+// Unless explicitly stated otherwise all files in this repository are licensed
+// under the Apache License Version 2.0.
+// This product includes software developed at Datadog (https://www.datadoghq.com/).
+// Copyright 2016-present Datadog, Inc.
+
+package pipeline
+
+import (
+	"github.com/DataDog/datadog-agent/comp/logs/agent/config"
+)
+
+// applyRoutingHeaders sets x-dd-logs-routing on non-nodeless endpoints based on
+// the primary transport, or strips it entirely for nodeless nodes.
+func applyRoutingHeaders(endpoints *config.Endpoints, nodeless bool) {
+	if nodeless {
+		stripRoutingHeader(endpoints)
+		return
+	}
+
+	var routingValue string
+	if endpoints.UseGRPC {
+		routingValue = "grpc"
+	} else if endpoints.UseHTTP {
+		routingValue = "http"
+	} else {
+		return
+	}
+
+	if endpoints.Main.ExtraHTTPHeaders == nil {
+		endpoints.Main.ExtraHTTPHeaders = map[string]string{}
+	}
+	endpoints.Main.ExtraHTTPHeaders["x-dd-logs-routing"] = routingValue
+	if len(endpoints.Endpoints) > 0 {
+		if endpoints.Endpoints[0].ExtraHTTPHeaders == nil {
+			endpoints.Endpoints[0].ExtraHTTPHeaders = map[string]string{}
+		}
+		endpoints.Endpoints[0].ExtraHTTPHeaders["x-dd-logs-routing"] = routingValue
+	}
+}
+
+func stripRoutingHeader(endpoints *config.Endpoints) {
+	delete(endpoints.Main.ExtraHTTPHeaders, "x-dd-logs-routing")
+	for i := range endpoints.Endpoints {
+		delete(endpoints.Endpoints[i].ExtraHTTPHeaders, "x-dd-logs-routing")
+	}
+}
diff --git a/comp/logs-library/pipeline/nodeless_k8s.go b/comp/logs-library/pipeline/nodeless_k8s.go
new file mode 100644
index 000000000000..1831ee033625
--- /dev/null
+++ b/comp/logs-library/pipeline/nodeless_k8s.go
@@ -0,0 +1,33 @@
+// Unless explicitly stated otherwise all files in this repository are licensed
+// under the Apache License Version 2.0.
+// This product includes software developed at Datadog (https://www.datadoghq.com/).
+// Copyright 2016-present Datadog, Inc.
+
+//go:build kubelet
+
+package pipeline
+
+import (
+	"context"
+
+	pkgconfigmodel "github.com/DataDog/datadog-agent/pkg/config/model"
+	"github.com/DataDog/datadog-agent/pkg/util/kubernetes/hostinfo"
+	"github.com/DataDog/datadog-agent/pkg/util/log"
+)
+
+// isNodelessNode returns true when the current node has the label class=nodeless.
+func isNodelessNode(_ pkgconfigmodel.Reader) bool {
+	nodeInfo, err := hostinfo.NewNodeInfo()
+	if err != nil {
+		log.Debugf("logs-agent: could not create NodeInfo to check nodeless label: %v", err)
+		return false
+	}
+
+	labels, err := nodeInfo.GetNodeLabels(context.Background())
+	if err != nil {
+		log.Debugf("logs-agent: could not get node labels: %v", err)
+		return false
+	}
+
+	return labels["class"] == "nodeless"
+}
diff --git a/comp/logs-library/pipeline/nodeless_nok8s.go b/comp/logs-library/pipeline/nodeless_nok8s.go
new file mode 100644
index 000000000000..601c9ab6082a
--- /dev/null
+++ b/comp/logs-library/pipeline/nodeless_nok8s.go
@@ -0,0 +1,17 @@
+// Unless explicitly stated otherwise all files in this repository are licensed
+// under the Apache License Version 2.0.
+// This product includes software developed at Datadog (https://www.datadoghq.com/).
+// Copyright 2016-present Datadog, Inc.
+
+//go:build !kubelet
+
+package pipeline
+
+import (
+	pkgconfigmodel "github.com/DataDog/datadog-agent/pkg/config/model"
+)
+
+// isNodelessNode always returns false when not built with kubelet support.
+func isNodelessNode(_ pkgconfigmodel.Reader) bool {
+	return false
+}
diff --git a/comp/logs-library/pipeline/provider.go b/comp/logs-library/pipeline/provider.go
index 7b76e592eae5..a3e5fde326de 100644
--- a/comp/logs-library/pipeline/provider.go
+++ b/comp/logs-library/pipeline/provider.go
@@ -99,6 +99,17 @@ func NewProvider(
 	var senderImpl sender.PipelineComponent
 	serverlessMeta := sender.NewServerlessMeta(serverless)
 
+	nodeless := isNodelessNode(cfg)
+
+	// Nodeless nodes must not use gRPC (not zonally balanced); fall back to HTTP.
+	if nodeless && endpoints.UseGRPC {
+		endpoints.UseGRPC = false
+		endpoints.UseHTTP = true
+	}
+
+	// Inject or strip the x-dd-logs-routing header based on node type and transport.
+	applyRoutingHeaders(endpoints, nodeless)
+
 	if endpoints.UseGRPC {
 		senderImpl = grpcsender.NewSender(numberOfPipelines, cfg, sink, endpoints, destinationsContext, compression)
 	} else if endpoints.UseHTTP {