diff --git a/Formula/r/ruff.rb b/Formula/r/ruff.rb
index cc6a841d24a7..c6269a245b9c 100644
--- a/Formula/r/ruff.rb
+++ b/Formula/r/ruff.rb
@@ -1,18 +1,18 @@
 class Ruff < Formula
   desc "Extremely fast Python linter, written in Rust"
   homepage "https://docs.astral.sh/ruff/"
-  url "https://github.com/astral-sh/ruff/archive/refs/tags/0.15.20.tar.gz"
-  sha256 "3d2d9283f8221d04f1debf1ac32ec900bba08aec5609266ac93b8b8464073d16"
+  url "https://github.com/astral-sh/ruff/archive/refs/tags/0.15.21.tar.gz"
+  sha256 "1916f5c69d8f0b6f06242b94f4326bc6d3f1865c85dc8cbe843b36d88c6baac4"
   license "MIT"
   head "https://github.com/astral-sh/ruff.git", branch: "main"
 
   bottle do
-    sha256 cellar: :any_skip_relocation, arm64_tahoe:   "d18974577d96aaf0fbd16297d6d7dc213efb38af1728331c52a36240f5efcd85"
-    sha256 cellar: :any_skip_relocation, arm64_sequoia: "a37bc28e03a7ef44178e6c9a9ee66472728edeb7d75eea58332d475035410949"
-    sha256 cellar: :any_skip_relocation, arm64_sonoma:  "27247354fe247dbd1608608e70a2e60bd6a9dfeca8064a09743ad2d46a5e06be"
-    sha256 cellar: :any_skip_relocation, sonoma:        "e68e0937d132f5bc08d3dca04b7f69f94a613b1e5bb192caab9d50b858170036"
-    sha256 cellar: :any,                 arm64_linux:   "0ae86d165a08efbcb76c681306e5ceb28144aca8b5f73ac3ee189096ecae3a1a"
-    sha256 cellar: :any,                 x86_64_linux:  "d5b434d30445a68809f4545a0a090623e474065dfa3583299bd89c164f99ef46"
+    sha256 cellar: :any_skip_relocation, arm64_tahoe:   "a5b3da1afb76c188fa59ec74cf5d36a9529ecd74e9b7945a36bd008314ab8009"
+    sha256 cellar: :any_skip_relocation, arm64_sequoia: "0f9b3808f3610e388045ba7f84f59ced452c7423299dd482b7513e6436647aaa"
+    sha256 cellar: :any_skip_relocation, arm64_sonoma:  "bc572c98d8da65679252c2a899c8f758c7550f1b161deb2c0ca148de14517d32"
+    sha256 cellar: :any_skip_relocation, sonoma:        "64929fc7d6aece30f114bae2841baa7e7b54159b541832ec4b9723995a58ac91"
+    sha256 cellar: :any,                 arm64_linux:   "a3b6d836cd955f35b38930c20e3d4052a5b9e9e455d5f827d0bfc84d2fa0a3a7"
+    sha256 cellar: :any,                 x86_64_linux:  "1c8589c777293b6313aed799d5bb4e49d34ad799a7e7c315a8448c949e679949"
   end
 
   depends_on "rust" => :build