diff --git a/starlette/middleware/trustedhost.py b/starlette/middleware/trustedhost.py
index 98451e29f..0d50d0199 100644
--- a/starlette/middleware/trustedhost.py
+++ b/starlette/middleware/trustedhost.py
@@ -37,7 +37,16 @@ async def __call__(self, scope: Scope, receive: Receive, send: Send) -> None:
             return
 
         headers = Headers(scope=scope)
-        host = headers.get("host", "").split(":")[0]
+        host = headers.get("host", "")
+        if host.startswith("["):
+            closing_bracket = host.find("]")
+            suffix = host[closing_bracket + 1 :] if closing_bracket != -1 else ""
+            if closing_bracket != -1 and (
+                not suffix or (suffix.startswith(":") and suffix[1:].isascii() and suffix[1:].isdigit())
+            ):
+                host = host[: closing_bracket + 1]
+        else:
+            host = host.split(":", 1)[0]
         is_valid_host = False
         found_www_redirect = False
         for pattern in self.allowed_hosts:
diff --git a/tests/middleware/test_trusted_host.py b/tests/middleware/test_trusted_host.py
index 5b8b217c3..5ac86cebc 100644
--- a/tests/middleware/test_trusted_host.py
+++ b/tests/middleware/test_trusted_host.py
@@ -29,6 +29,29 @@ def homepage(request: Request) -> PlainTextResponse:
     assert response.status_code == 400
 
 
+def test_trusted_host_middleware_with_ipv6(test_client_factory: TestClientFactory) -> None:
+    def homepage(request: Request) -> PlainTextResponse:
+        return PlainTextResponse("OK", status_code=200)
+
+    app = Starlette(
+        routes=[Route("/", endpoint=homepage)],
+        middleware=[Middleware(TrustedHostMiddleware, allowed_hosts=["[::1]"])],
+    )
+
+    client = test_client_factory(app)
+    response = client.get("/", headers={"host": "[::1]:8000"})
+    assert response.status_code == 200
+
+    response = client.get("/", headers={"host": "[::1]:attacker"})
+    assert response.status_code == 400
+
+    response = client.get("/", headers={"host": "[::1]:"})
+    assert response.status_code == 400
+
+    response = client.get("/", headers={b"host": b"[::1]:\xb2"})
+    assert response.status_code == 400
+
+
 def test_default_allowed_hosts() -> None:
     app = Starlette()
     middleware = TrustedHostMiddleware(app)