diff --git a/docs/zh/examples/tadf.md b/docs/zh/examples/tadf.md new file mode 100644 index 000000000..93ee71952 --- /dev/null +++ b/docs/zh/examples/tadf.md @@ -0,0 +1,170 @@ +# 热活化延迟荧光材料（TADF）性质预测 + +!!! note + + 1. 开始训练、评估前，请先确保性质数据文件(.dat)和SMILES(smis.txt)数据文件的存在，并对应修改 yaml 配置文件中的 `data_dir` 为性质数据文件路径，`sim_dir` 为SMILES数据文件路径。 + 2. 如果需要使用预训练模型进行评估，请先下载预训练模型[Est.pdparams](https://paddle-org.bj.bcebos.com/paddlescience/models/TADF/Est/Est_pretrained.pdparams), [f.pdparams](https://paddle-org.bj.bcebos.com/paddlescience/models/TADF/f/f_pretrained.pdparams), 并对应修改 yaml 配置文件中的 `load_model_path` 为模型参数路径。 + 3. 开始训练、评估前，请安装 `rdkit` 等，相关依赖请执行`pip install -r requirements.txt`安装。 + +| 预训练模型 | 指标 | +|:--| :--| +| [Est.pdparams](https://paddle-org.bj.bcebos.com/paddlescience/models/TADF/Est/Est_pretrained.pdparams) | loss(MAE): 0.045 | +| [f.pdparams](https://paddle-org.bj.bcebos.com/paddlescience/models/TADF/f/f_pretrained.pdparams) | loss(MAE): 0.036 | +| [angle.pdparams](https://paddle-org.bj.bcebos.com/paddlescience/models/TADF/angle/angle_pretrained.pdparams) | loss(MAE): 0.041 | + +=== "模型训练命令" + + ``` sh + #Est 预测: + cd TADF_angle + python Est.py mode=train + cd ../ + + #f 预测: + cd TADF_f + python f.py mode=train + cd ../ + + # angle 预测: + cd TADF_angle + python angle.py mode=train + cd ../ + ``` + +=== "模型评估命令" + + ``` sh + #Est 评估： + cd TADF_angle + python Est.py + cd ../ + + #f 评估: + cd TADF_f + python f.py + cd ../ + + # angle 评估: + cd TADF_angle + python angle.py + cd ../ + ``` + +## 1. 背景简介 + +有机发光二极管（OLED）具有高效率、结构灵活和低成本的优势，在先进显示和照明技术中受到广泛关注。在有机发光二极管器件中，电注入载流子以1：3的比例形成单线态和三线态激子。以纯荧光材料为发光材料构建的OLED发光效率IQE理论极限为25%。另一方面，有机金属复合物发光材料通过引入稀有金属（Ir，Pt等）带来强自旋轨道耦合（SOC），可以将单线态激子通过系间窜越过程转化成三线态激子，从而利用三线态激子发出磷光，其IQE可达100%，但是稀有金属价格昂贵，为推广使用带来了阻碍。热活化延迟荧光材料（TADF）为解决这些问题提供了新思路，并引起了广泛关注。在TADF中，三线态通过逆系间窜越过程（RISC）转化成单重态并发出荧光，从而实现100%的IQE，而RISC过程很大程度上取决于最低单线态（S1）和最低三线态（T1） 之间的能隙（$\Delta Est$）。根据量子力学理论，ΔEST相当于HOMO和LUMO之间的交换积分的两倍。因此TADF分子的常见设计策略是将电子供体（D）和电子受体（A）以明显扭曲的二面角结合以实现HOMO和LUMO在空间上明显的分离。然而，与$\Delta Est$相反，振子强度（$f$）需要较大的HOMO和LUMO之间的重叠积分，这二者之间的矛盾需要进一步平衡。 + +## 2. 模型原理 + +通过高通量计算构建数据集，通过分子结构输入、指纹特征提取、特征降维三个环节实现分子特征表征，随后通过多层非线性变换学习分子结构特征与TADF关键参数间的复杂映射关系，最终实现端到端的性质预测。 + +## 3. TADF性质预测模型的实现 + +本样例包括对化学分子的能隙($\Delta Est$)，振子强度($f$)，电子供体与电子受体间的二面角($angle$)三项性质的预测，接下来将以二面角$angle$为例，开始讲解如何基于PaddleScience代码，实现对于TADF性质预测模型的构建、训练、测试和评估。案例的目录结构如下： + +``` log +tadf/ +├──TADF_angle/ +│ ├── config/ +│ │ └── angle.yaml +│ ├── angle_model.py +│ ├── angle.dat +│ ├── angle.py +│ └── smis.txt +├── TADF_Est/ +│ └── ... +├── TADF_f/ +│ └── ... +└── requirements.txt +``` + +### 3.1 数据集准备 + +我们选择常用的49个受体和50个受体以单键相连的方式进行组合，通过穷举所有可能的组合位点我们得到了44470个分子。通过MMFF94力场优化得到分子的初始结构。从44470个分子中随机提取5136个分子，在B3LYP/6-31G（d）水平下对5136个分子进行基态结构优化，采用TDDFT方法在基态构型下进行激发态性质计算。 + +每项分子性质数据包括性质数据文件（例如angle.dat）和SMILES数据文件（smis.txt）。首先依据配置文件的信息逐行对性质数据文件和SMILES数据文件进行加载，随后通过分子指纹生成、异常处理、降维处理将SMILES分子式转换为可用于机器学习的特征向量，完成数据集的准备，用 PaddleScience 代码表示如下 + +``` py linenums="20" title="examples/tadf/TADF_angle/angle_model.py" +--8<-- +examples/tadf/TADF_angle/angle_model.py:20:57 +--8<-- +``` + +### 3.2 约束构建 + +本研究采用监督学习，按照 PaddleScience 的API结构说明，采用内置的 `SupervisedConstraint` 构建监督约束。用 PaddleScience 代码表示如下 + +``` py linenums="88" title="examples/tadf/TADF_angle/angle_model.py" +--8<-- +examples/tadf/TADF_angle/angle_model.py:88:100 +--8<-- +``` + +`SupervisedConstraint` 的第二个参数表示采用均方误差 `MSELoss` 作为损失函数，第三个参数表示约束条件的名字，方便后续对其索引。 + +### 3.3 模型构建 + +对于三个预测对象，设计了相同的深度神经网络，网络结构为含有两层隐藏层的神经网络，第一层隐藏层含有587个神经元，第二层隐藏层含有256个神经元，隐藏层之间加入Dropout。以$angle$预测为例，用 PaddleScience 代码表示如下 + +``` py linenums="106" title="examples/tadf/TADF_angle/angle_model.py" +--8<-- +examples/tadf/TADF_angle/angle_model.py:106:111 +--8<-- +``` + +### 3.4 优化器构建 + +在本案例的angle性质预测中，训练器采用Adam优化器，学习率设置为0.01，`weight_decay` 设置为 1e-5，用 PaddleScience 代码表示如下 + +``` py linenums="112" title="examples/tadf/TADF_angle/angle_model.py" +--8<-- +examples/tadf/TADF_angle/angle_model.py:112:117 +--8<-- +``` + +### 3.5 模型训练 + +完成上述设置之后，只需要将上述实例化的对象按顺序传递给`ppsci.solver.Solver`，然后启动训练即可。用PaddleScience 代码表示如下 + +``` py linenums="119" title="examples/tadf/TADF_angle/angle_model.py" +--8<-- +examples/tadf/TADF_angle/angle_model.py:119:131 +--8<-- +``` + +## 4. 完整代码 + +``` py linenums="1" title="examples/tadf/TADF_angle/angle_model.py" +--8<-- +examples/tadf/TADF_angle/angle_model.py +--8<-- +``` + +``` py linenums="1" title="examples/tadf/TADF_angle/angle.py" +--8<-- +examples/tadf/TADF_angle/angle.py +--8<-- +``` + +## 5. 结果展示 + +下图展示能隙($\Delta Est$)，振子强度($f$)，电子供体与电子受体间的二面角($angle$)三项性质的模型预测结果。 + +
+ ![test_est.png](https://paddle-org.bj.bcebos.com/paddlescience/docs/TADF/Est/test_est.png){ loading=lazy } +
能隙(ΔEst)的模型预测结果
+
+ +
+ ![test_f.png](https://paddle-org.bj.bcebos.com/paddlescience/docs/TADF/f/test_f.png){ loading=lazy } +
振子强度(f)的模型预测结果
+
+ +
+ ![test_theta.png](https://paddle-org.bj.bcebos.com/paddlescience/docs/TADF/angle/test_theta.png){ loading=lazy } +
电子供体与电子受体间的二面角(angle)的模型预测结果
+
+ +## 6. 参考文献 + +Yufei Bu, Qian Peng*, Designing Promising Thermally Activated Delayed Fluroscence Emitters via Machine Learning-Assisted High-Throughput Virtual Screening. J. Phys. Chem. C. 2023. DOI: 10.1021/acs.jpcc.3c05337. diff --git a/examples/tadf/TADF_Est/Est.dat b/examples/tadf/TADF_Est/Est.dat new file mode 100644 index 000000000..f7dd5fa45 --- /dev/null +++ b/examples/tadf/TADF_Est/Est.dat @@ -0,0 +1,5136 @@ +1.3953000000000002 +0.7289000000000003 +0.8776999999999999 +0.867 +1.1407000000000003 +1.0627000000000004 +0.6800999999999999 +0.6111 +0.01670000000000016 +0.48360000000000003 +1.1124 +1.0095999999999998 +0.9831000000000003 +1.1089000000000002 +0.8616999999999999 +0.5010000000000003 +0.9453 +0.8451 +0.6073000000000004 +1.3138999999999998 +0.19639999999999969 +0.6700999999999997 +0.06669999999999998 +0.3498999999999999 +0.31220000000000026 +0.4443999999999999 +0.24460000000000015 +0.3496999999999999 +0.698 +0.17149999999999999 +0.9037999999999999 +0.7867999999999999 +0.6202000000000001 +1.1169000000000002 +0.8666 +1.0627 +0.9655999999999998 +1.0878 +1.1936 +1.1697000000000002 +1.0519000000000003 +1.2468 +0.9731000000000001 +1.0541 +0.8431000000000002 +0.8815 +0.8651999999999997 +0.9413999999999998 +1.0522 +1.0242 +0.9408000000000003 +1.1488999999999998 +0.22219999999999995 +0.7775999999999996 +0.956 +1.0112 +0.8635000000000002 +1.1158999999999994 +1.02 +0.6650999999999998 +1.004 +0.7323999999999997 +1.0305 +0.33020000000000005 +0.8963999999999999 +0.8233999999999999 +0.8529999999999998 +0.8946999999999998 +1.0081000000000002 +1.0173 +0.7696000000000001 +1.0561000000000003 +0.3937999999999997 +0.6541999999999999 +0.7072999999999996 +0.36650000000000027 +0.48139999999999983 +1.0421999999999998 +0.9228999999999998 +0.8146999999999998 +0.6193999999999997 +0.8136999999999999 +0.8137000000000003 +1.1189 +1.0446000000000004 +0.7875000000000001 +1.0396 +1.0655999999999999 +0.8447 +0.9457999999999998 +0.2836999999999996 +0.09109999999999996 +0.22919999999999963 +0.03929999999999989 +0.24799999999999978 +0.6085000000000003 +0.6227 +0.8542000000000001 +0.7326000000000001 +0.9062000000000001 +0.7613999999999996 +1.4968999999999997 +1.2077 +1.0222000000000002 +0.8843000000000001 +1.1551999999999998 +0.7696999999999998 +1.0776999999999997 +0.6657000000000002 +0.8427000000000002 +0.7324000000000002 +1.1351999999999998 +0.8336999999999999 +1.1753000000000005 +0.9750999999999999 +1.0576999999999996 +1.1461999999999999 +0.9198 +1.08 +1.0604999999999998 +1.036 +0.8073999999999999 +1.1427999999999998 +1.1732999999999998 +1.3177000000000003 +0.9363999999999999 +0.7928000000000002 +0.8856000000000002 +1.0793999999999997 +1.0846999999999998 +0.8084000000000002 +1.1526 +1.2924999999999995 +0.8239000000000001 +1.0459 +0.8523999999999998 +1.2627000000000002 +1.3172000000000006 +0.7086999999999999 +0.4455999999999998 +1.0543 +0.9427000000000003 +0.7947000000000002 +0.9064999999999999 +0.8538999999999999 +0.4793999999999996 +0.8024 +1.2404999999999995 +1.1110000000000002 +1.1326999999999998 +0.8452000000000002 +1.2022 +0.8681000000000001 +0.9802 +0.19610000000000039 +0.6871 +0.7378999999999998 +0.9049 +0.7765 +0.7187999999999999 +0.07820000000000027 +0.5783 +0.7395999999999998 +0.5032000000000001 +0.9491 +0.6343999999999999 +0.681 +0.8235000000000001 +1.0385 +0.8874999999999997 +0.8141000000000003 +1.1417000000000002 +0.7465000000000002 +0.8181999999999996 +1.0362999999999998 +0.8043999999999998 +0.8799999999999999 +1.1532999999999998 +1.2437999999999998 +0.8154999999999997 +0.9076999999999997 +1.1366999999999998 +1.1457000000000002 +0.7824999999999998 +0.36050000000000004 +0.8077000000000001 +0.8003 +0.17039999999999988 +0.05209999999999981 +1.009 +0.9348000000000001 +1.0424000000000002 +0.6903999999999999 +0.5174000000000003 +0.9169999999999998 +0.8785000000000003 +1.1879000000000004 +0.5815000000000001 +0.6467999999999998 +0.8732000000000002 +0.7277999999999998 +0.7605000000000004 +1.1679 +0.9097999999999997 +1.0274999999999999 +1.7124000000000001 +0.8304 +1.4047999999999994 +1.5332 +1.8779 +1.3363 +1.4327999999999999 +0.6169000000000002 +0.8416000000000001 +0.8553000000000002 +0.4218000000000002 +0.3889 +0.34189999999999987 +0.8317999999999999 +1.0581 +1.1162 +1.0746000000000002 +0.9305000000000003 +0.8733 +0.8744999999999998 +0.7713999999999999 +0.8990999999999998 +0.9287000000000001 +0.9863 +0.6434000000000002 +1.0697 +0.6983000000000001 +1.0407000000000002 +1.1269 +0.9259000000000004 +0.6985000000000001 +0.11000000000000032 +0.5247000000000002 +0.8492999999999999 +0.7082999999999999 +0.8058000000000001 +0.9712000000000001 +0.04150000000000009 +0.09220000000000006 +0.24069999999999991 +0.33130000000000015 +1.2273 +0.8177999999999996 +1.4712 +1.7107 +1.1206999999999998 +1.3166000000000002 +1.6775000000000002 +0.8580999999999999 +1.4926 +1.0117000000000003 +0.8597999999999999 +0.8435999999999999 +1.3605999999999998 +0.7007000000000003 +1.0773000000000001 +0.9965999999999999 +1.1502000000000003 +1.0785999999999998 +1.2698 +1.1345 +0.8303000000000003 +0.8976000000000002 +0.7708999999999997 +1.1760999999999995 +0.9716 +0.6482999999999999 +0.7876999999999996 +0.7222 +0.8598999999999997 +0.8737000000000004 +1.0648 +1.0934 +0.7247000000000003 +0.8977000000000004 +1.1036000000000001 +1.0642 +1.0654999999999997 +0.8263999999999996 +1.0759000000000003 +0.7916000000000003 +0.9990999999999999 +1.1075 +0.7344999999999997 +0.9539 +0.8590999999999998 +1.1513999999999998 +1.2284000000000002 +0.8559999999999999 +0.9232999999999998 +0.8452999999999999 +0.7000000000000002 +0.7272999999999996 +1.0263 +0.7616 +0.9441999999999999 +0.7410000000000001 +1.0452 +0.8212999999999999 +0.9217 +0.9453 +1.2721999999999998 +1.3519 +1.1754000000000002 +0.7961 +1.1752000000000002 +0.8890000000000002 +0.7681 +1.4615999999999998 +1.6919 +0.20440000000000014 +0.04700000000000015 +0.5489999999999999 +0.6312000000000002 +0.8723999999999998 +0.6374999999999997 +0.7485000000000004 +0.7111999999999998 +0.6890999999999998 +0.6400000000000001 +0.8157000000000001 +0.7968000000000002 +1.109 +0.3359000000000001 +0.6221999999999999 +0.6063000000000001 +0.6972 +0.9545999999999997 +1.3133 +0.7952000000000004 +0.5692999999999997 +0.8898000000000001 +1.3650000000000002 +0.9336000000000002 +0.3999999999999999 +0.19810000000000016 +0.9632000000000001 +0.746 +0.4317000000000002 +0.8729 +0.8456000000000001 +0.5388999999999999 +0.9464000000000001 +1.0577999999999994 +0.8301999999999996 +1.5070000000000001 +0.8719999999999999 +0.5465 +1.0818000000000003 +1.1652999999999998 +1.0279000000000003 +0.2763 +0.9847999999999999 +1.0419000000000005 +1.0804999999999998 +0.9211000000000005 +1.1856 +1.1404999999999998 +0.5061 +0.8266999999999998 +0.8054000000000001 +0.8085 +0.8247999999999998 +0.8971999999999998 +0.9870000000000001 +0.6191 +0.7843 +0.6191 +0.6434000000000002 +0.6379999999999999 +0.7332999999999998 +0.7157 +0.9213 +1.1276000000000002 +1.2942999999999998 +0.8199000000000001 +0.13070000000000004 +1.0628000000000002 +0.8344 +1.1581000000000001 +1.2559 +0.8839999999999999 +1.0333 +1.2637999999999998 +1.0473 +1.1191 +1.0718 +1.1529000000000003 +0.8603000000000001 +1.1341 +0.8516000000000004 +1.0302000000000002 +0.3876999999999997 +0.863 +0.5232999999999999 +0.6101999999999999 +1.0306000000000002 +0.9596 +1.4676 +0.5786000000000002 +0.8178999999999998 +1.2277 +1.4066 +1.0171999999999999 +0.9108 +0.7440000000000002 +1.1448999999999998 +1.1360999999999999 +1.1121999999999996 +0.556 +1.0648999999999997 +1.1249000000000002 +1.0251000000000001 +0.8093999999999997 +0.9321000000000002 +0.7837999999999998 +1.1250999999999998 +0.9512 +1.0175 +0.7555999999999998 +1.0032999999999999 +1.0393000000000003 +1.0169000000000001 +1.1031 +1.2549000000000001 +1.0997000000000003 +0.8717000000000001 +0.7966000000000002 +0.8925000000000001 +0.855 +0.9464999999999999 +1.2289000000000003 +1.2579000000000002 +1.1284 +0.9377 +0.8108000000000004 +0.9358 +1.12 +1.0985999999999998 +1.1705 +1.0937000000000001 +1.1359999999999997 +0.7422 +0.8390999999999997 +0.7185000000000001 +0.9091 +1.0437000000000003 +0.9323000000000001 +1.0852999999999997 +0.9906999999999999 +1.0139999999999998 +0.8916 +0.8780999999999999 +0.7604000000000002 +0.9758 +1.0070999999999999 +0.9182000000000001 +1.0678 +0.9621 +0.5842999999999998 +1.0554000000000001 +1.1453000000000002 +0.9708999999999999 +0.8715999999999999 +1.2248999999999994 +1.0015999999999998 +1.2180000000000004 +0.7492999999999999 +1.1157 +0.6396999999999999 +1.1084 +0.6411000000000002 +1.1132 +0.28600000000000003 +0.6135999999999999 +0.4039999999999999 +0.9825999999999997 +0.2724000000000002 +1.0484000000000004 +0.6848999999999998 +0.5808 +0.9428999999999998 +0.7000000000000002 +0.6861000000000002 +1.1494 +0.6732 +0.9541 +1.1577000000000002 +0.7957000000000001 +0.1618999999999997 +0.7425999999999999 +0.29499999999999993 +0.15080000000000027 +0.3900999999999999 +0.2875000000000001 +0.16769999999999996 +0.1376000000000004 +0.3844000000000003 +0.9693999999999998 +0.03110000000000035 +0.7524000000000002 +0.6107999999999998 +0.4293 +0.8700000000000001 +0.6710999999999996 +0.9170000000000003 +0.25760000000000005 +1.0503999999999998 +0.6919 +0.5539000000000001 +0.9001999999999999 +0.7319 +0.6655000000000002 +0.9772999999999996 +0.9774000000000003 +0.22140000000000004 +0.5515000000000003 +0.24150000000000027 +0.013799999999999812 +0.2669999999999999 +1.0548000000000002 +0.9131 +1.1069999999999998 +0.6747000000000001 +0.5455999999999999 +0.7117 +0.8346999999999998 +1.2024 +0.6961000000000004 +0.29610000000000003 +0.18270000000000008 +1.1168999999999998 +0.9931000000000001 +1.2280000000000002 +0.9563000000000001 +0.5002 +0.7577000000000003 +0.9920999999999998 +0.9182000000000001 +0.9284000000000003 +1.1047000000000002 +0.11909999999999998 +0.33230000000000004 +0.6344999999999996 +0.36980000000000013 +0.5836000000000001 +0.4811000000000001 +0.3578000000000001 +0.3480000000000003 +0.6297999999999999 +0.15249999999999986 +0.5537999999999998 +0.2749999999999999 +0.7700999999999998 +0.8969999999999998 +1.0194999999999999 +0.5624000000000002 +0.6972 +0.5959999999999996 +0.8963000000000001 +0.9526000000000003 +1.0280999999999998 +0.9394 +0.41800000000000015 +0.7803 +0.6356000000000002 +1.0173 +0.8649999999999998 +0.6852 +1.0337999999999998 +0.9308999999999998 +0.6463999999999999 +0.24549999999999983 +0.8452000000000002 +0.9826999999999999 +1.0582000000000003 +0.8286000000000002 +1.0048999999999997 +0.9108 +0.6377000000000002 +1.0220000000000002 +1.0074 +1.0670000000000002 +0.9108 +0.8234999999999997 +0.16049999999999986 +0.29610000000000003 +0.6747000000000001 +0.6412 +1.0725000000000002 +0.8754 +0.6867999999999999 +0.12009999999999987 +0.8448000000000002 +0.35619999999999985 +0.7536 +0.6648000000000001 +0.38670000000000027 +0.6543999999999999 +0.4382999999999999 +0.4248000000000003 +0.8249 +0.8794999999999997 +0.7525 +0.19510000000000005 +0.7107000000000001 +0.9812000000000003 +0.9975999999999998 +0.6678999999999999 +0.7251000000000003 +0.8018999999999998 +1.0794000000000001 +1.1537999999999995 +0.8494999999999999 +0.7888999999999999 +0.4518 +0.4941 +0.758 +0.6930999999999998 +0.6587000000000001 +0.7051000000000003 +1.1121000000000003 +0.49819999999999975 +0.25360000000000005 +1.0029 +0.5429999999999997 +0.7976000000000001 +0.8233999999999999 +0.7723 +0.7273000000000001 +0.8304 +0.6718999999999999 +1.0585999999999998 +0.3317000000000001 +0.6490999999999998 +0.09629999999999983 +0.8571 +0.7410999999999999 +0.8421000000000003 +0.8697999999999997 +0.8805999999999998 +1.1290999999999998 +0.3963000000000001 +0.6149 +0.9087000000000001 +0.2891999999999997 +0.04170000000000007 +0.28069999999999995 +0.3378000000000001 +0.7191000000000001 +0.5930999999999997 +0.5300000000000002 +0.5644999999999998 +0.5298000000000003 +0.27669999999999995 +0.21130000000000004 +0.44819999999999993 +0.6346000000000003 +0.5985 +0.49540000000000006 +0.4767999999999999 +0.46160000000000023 +0.1221000000000001 +0.1271 +0.5337000000000001 +0.4586000000000001 +0.4496000000000002 +0.3753000000000002 +0.28200000000000003 +0.4262999999999999 +0.2986 +0.5853999999999999 +0.7289999999999996 +0.7274000000000003 +0.15939999999999976 +0.3423999999999996 +0.12699999999999978 +0.20940000000000003 +0.30059999999999976 +0.1301000000000001 +0.03960000000000008 +0.35139999999999993 +0.34999999999999964 +0.8637999999999999 +0.39480000000000004 +0.1879000000000004 +0.28390000000000004 +0.2836000000000003 +1.3527999999999998 +1.0985999999999998 +0.3687 +1.1507 +1.2359 +1.1482 +1.4348999999999998 +1.1208 +1.1725999999999996 +0.9939 +0.7047000000000003 +0.7452999999999999 +0.9819 +1.2742999999999998 +0.9208000000000003 +0.5123000000000002 +0.9885999999999999 +0.8674 +0.9144999999999999 +0.9199999999999999 +0.6993999999999998 +1.0349 +0.9516000000000004 +0.5813999999999999 +0.7808000000000002 +0.45599999999999996 +1.3588999999999998 +1.1673999999999998 +1.1545999999999998 +1.4134000000000002 +0.6534 +0.9359999999999999 +1.3044999999999995 +0.7062000000000004 +0.5827999999999998 +0.9968999999999997 +0.5244 +0.8124000000000002 +0.5156999999999998 +0.6419999999999999 +0.3020999999999998 +0.05690000000000017 +0.9791000000000003 +0.48360000000000003 +0.39860000000000007 +0.053999999999999826 +0.49770000000000003 +0.42600000000000016 +0.38759999999999994 +0.6407000000000003 +0.28569999999999984 +0.5377000000000001 +0.6288999999999998 +0.3761000000000001 +0.6430000000000002 +0.6508000000000003 +0.6663000000000001 +0.7593000000000001 +0.9939 +1.0479000000000003 +0.6103000000000001 +1.1203000000000003 +0.7370000000000001 +0.7424999999999997 +0.6530999999999998 +0.21369999999999978 +0.10660000000000025 +0.42969999999999997 +0.06409999999999982 +0.03229999999999977 +0.3708 +0.4657 +0.3696999999999999 +0.49140000000000006 +0.6612 +0.2764000000000002 +0.42269999999999985 +0.5783999999999998 +0.2965 +0.45040000000000013 +1.0478999999999998 +1.1871999999999998 +0.6206999999999998 +0.26639999999999997 +0.31999999999999984 +0.9106999999999998 +0.15670000000000028 +0.9062000000000001 +0.058699999999999974 +0.14380000000000015 +0.029199999999999893 +0.2966000000000002 +0.1806000000000001 +1.0476999999999999 +1.0069 +0.6579000000000002 +0.5421999999999998 +1.0010000000000003 +0.8567 +0.8996 +0.7867999999999999 +0.8151999999999999 +0.8558999999999997 +0.6580999999999997 +0.8751000000000002 +0.9619000000000004 +0.43520000000000003 +1.0711 +0.8233999999999999 +0.6135000000000002 +0.9323000000000001 +0.9973000000000001 +0.5918999999999999 +0.8475000000000001 +0.8661999999999996 +0.8071999999999999 +0.5661 +0.7454000000000001 +0.5794999999999999 +1.0317999999999996 +1.0202 +0.8029999999999999 +0.7161 +0.9181999999999997 +0.8681999999999999 +0.8089 +0.964 +0.774 +0.9198 +1.0253 +0.5604 +0.8736000000000002 +0.3965000000000001 +0.7883 +0.9110999999999998 +0.7626 +0.6713999999999998 +0.6362999999999999 +0.17779999999999996 +0.3506999999999998 +0.9086000000000003 +0.5526 +0.5575000000000001 +0.7996000000000003 +0.3362000000000003 +0.4365000000000001 +0.7652999999999999 +0.8963999999999999 +0.6513 +0.6141000000000001 +0.5755000000000003 +0.9464000000000001 +0.7399 +0.9575999999999998 +0.7235 +0.9224999999999999 +0.508 +0.5724999999999998 +1.0044000000000004 +1.0671 +0.6738000000000004 +0.9126999999999996 +0.8336000000000001 +0.7635999999999998 +0.8075999999999999 +0.8031000000000001 +0.7021000000000002 +0.7042000000000002 +0.6804999999999999 +0.8460000000000001 +0.8289 +0.7623000000000002 +0.4860000000000002 +0.8870999999999998 +0.6904999999999997 +0.41110000000000024 +0.8340999999999998 +0.6111 +0.8447999999999998 +0.6810999999999998 +0.8959999999999999 +0.7136999999999998 +0.5116 +0.8466 +0.5282 +1.0904000000000003 +0.7206999999999999 +0.6619999999999999 +0.6589 +0.6596000000000002 +0.6684000000000001 +0.7530999999999999 +0.5382000000000002 +0.9072999999999998 +0.7968999999999999 +0.6688000000000001 +0.9323999999999995 +0.7849999999999997 +0.9921999999999995 +0.6598999999999999 +0.5924999999999998 +0.8313999999999999 +0.8478999999999997 +0.5912999999999999 +0.7790999999999997 +0.8942000000000001 +0.8928000000000003 +0.35489999999999977 +0.6680999999999999 +0.8818999999999999 +0.8996 +0.9209 +0.9067000000000003 +0.8641000000000001 +0.9788999999999999 +0.7162999999999999 +0.7760000000000002 +0.1724000000000001 +0.6833 +0.4289999999999998 +0.1362000000000001 +0.3374999999999999 +0.2951999999999999 +0.03270000000000017 +0.5650999999999997 +0.25539999999999985 +0.4990000000000001 +0.4342999999999999 +0.48709999999999987 +1.0359999999999996 +0.22460000000000013 +0.8106 +0.32699999999999996 +0.4905000000000004 +0.5207999999999999 +0.45420000000000016 +0.4698000000000002 +0.4356 +0.45740000000000025 +0.5646 +0.9550000000000001 +0.8868999999999998 +0.8184999999999998 +0.8210000000000002 +0.9213999999999998 +0.5414999999999996 +0.3437999999999999 +0.48629999999999995 +0.28200000000000003 +0.42159999999999975 +0.43310000000000004 +0.371 +0.5728999999999997 +0.7986999999999997 +0.621 +0.30230000000000024 +0.7623000000000002 +0.5535999999999999 +0.4108999999999998 +0.5029000000000003 +0.2562000000000002 +0.5178000000000003 +0.4604999999999997 +0.22399999999999975 +0.09750000000000014 +0.015600000000000058 +0.3386999999999998 +0.18369999999999997 +0.49449999999999994 +0.1383000000000001 +0.5305 +0.36430000000000007 +0.3239000000000001 +0.5404 +0.4655 +0.9473000000000003 +0.7810000000000001 +0.8708 +0.7688999999999999 +0.3836999999999997 +0.17349999999999977 +0.7744999999999997 +0.6347 +0.6905999999999999 +0.8005 +0.3249000000000004 +0.7927 +1.1467 +0.7844000000000002 +0.4753000000000003 +0.6334 +0.6903999999999999 +0.5451999999999999 +1.1657000000000002 +0.5223999999999998 +0.4822000000000002 +0.4758 +0.5865 +0.8469000000000002 +0.6894999999999998 +0.927 +0.863 +0.6324999999999998 +0.9241999999999999 +1.0568 +0.6431 +0.6425000000000001 +0.6021999999999998 +0.9577 +0.7785000000000002 +0.9014000000000002 +0.8342 +0.8811 +0.8233000000000001 +0.45109999999999983 +1.0974 +0.8361000000000001 +0.6987999999999999 +0.964 +0.4547000000000003 +0.968 +0.2594999999999996 +0.9468000000000001 +0.9809000000000001 +1.0303999999999998 +0.9851999999999999 +0.5707 +0.8743999999999996 +0.8389000000000002 +1.0405000000000002 +1.0091 +0.8023000000000002 +0.9302999999999999 +0.8090999999999999 +1.0427999999999997 +1.0533000000000001 +0.30069999999999997 +0.5051999999999999 +0.9608999999999996 +0.9493 +0.3820000000000001 +1.0697 +1.1288 +1.1081999999999996 +1.1451000000000002 +1.1306999999999996 +0.9346000000000001 +1.1357 +1.0413000000000001 +0.49239999999999995 +1.1175000000000002 +1.0000999999999998 +0.8791000000000002 +1.0695999999999999 +1.0408999999999997 +0.8173000000000004 +0.9916999999999998 +1.1641 +0.8447 +0.6995999999999998 +0.5944000000000003 +0.9306000000000001 +1.0861999999999998 +1.0379 +0.9888000000000003 +1.1584000000000003 +0.4333999999999998 +0.9249 +0.5610999999999997 +1.1727000000000003 +1.0841000000000003 +0.7894000000000001 +0.8247 +1.1366999999999998 +1.0974 +0.8506 +0.5640000000000001 +0.8427000000000002 +1.0693000000000001 +0.5225 +0.5675999999999997 +1.1497000000000002 +1.0265999999999997 +0.9227000000000003 +0.5289999999999999 +0.9805999999999999 +0.9236999999999997 +0.5985 +0.9413 +1.1250999999999998 +1.0717000000000003 +0.7986999999999997 +0.44530000000000003 +0.9958999999999998 +0.9264000000000001 +0.8031999999999999 +1.0112 +0.9137 +0.7961 +1.1525999999999996 +0.9485000000000001 +0.8231999999999999 +1.0861999999999998 +1.0128999999999997 +0.7603 +0.9033000000000002 +0.8623000000000003 +1.1368999999999998 +1.1193 +1.0553 +0.5009000000000001 +1.0676 +1.1509999999999998 +1.1717 +1.1227 +1.1568 +1.1763 +0.7244999999999999 +0.8923999999999999 +1.1556000000000002 +0.07430000000000003 +0.7838000000000003 +0.3622000000000001 +0.4013 +0.9843999999999999 +1.1151999999999997 +0.6808000000000001 +1.0006 +1.0655999999999999 +0.9780000000000002 +1.0968 +0.2956000000000003 +1.0593 +0.919 +0.8801000000000001 +0.8832 +0.5779999999999998 +0.7987000000000002 +1.0703 +0.8971999999999998 +1.1540999999999997 +1.0146000000000002 +0.6713999999999998 +0.7435 +0.6214999999999997 +1.0431999999999997 +1.1253000000000002 +1.1769999999999996 +0.6080000000000001 +0.9691000000000001 +0.4857999999999998 +0.9359999999999999 +0.7676000000000003 +0.8722999999999996 +0.7505000000000002 +0.3734000000000002 +1.0497 +0.8296000000000001 +0.9026000000000001 +0.8033000000000001 +1.2092 +1.1988999999999996 +1.1263 +0.8793000000000002 +0.9432999999999998 +1.0419 +0.2477999999999998 +0.8831000000000002 +0.4557000000000002 +0.9521999999999999 +0.9844999999999997 +0.6298000000000004 +0.7662 +0.9487000000000001 +0.8576000000000001 +1.1178999999999997 +1.1208 +0.9807999999999999 +0.8525999999999998 +1.1730999999999998 +0.4028999999999998 +0.30699999999999994 +0.9308000000000001 +0.8891 +0.8967999999999998 +0.7601999999999998 +0.6812 +1.0206999999999997 +1.0248 +0.7471000000000001 +0.8622000000000001 +0.9967000000000001 +0.4197000000000002 +1.3856000000000002 +0.6899000000000002 +0.8563000000000001 +0.8153000000000001 +0.7635999999999998 +1.0086 +1.0248 +1.1692 +1.0453999999999999 +1.1249999999999996 +0.7384 +0.7953999999999999 +1.0331000000000001 +0.8757000000000001 +0.4906999999999999 +0.11410000000000009 +0.5417000000000001 +0.4870000000000001 +0.48870000000000013 +0.4899 +0.8782999999999999 +0.4737 +0.4906999999999999 +0.13759999999999994 +0.8855 +0.484 +0.49109999999999987 +1.214 +0.47829999999999995 +0.4884999999999997 +0.714 +0.9051 +1.2436999999999996 +0.8503000000000003 +0.45710000000000006 +0.8924000000000003 +1.0060000000000002 +0.8146 +0.42459999999999987 +0.36560000000000015 +1.1978 +1.0871 +0.9948000000000001 +0.5219 +0.41410000000000036 +0.5440999999999998 +0.8720000000000003 +0.9278999999999997 +0.3892000000000002 +0.7368999999999999 +0.8069999999999999 +0.7576999999999998 +0.7449999999999997 +0.44410000000000016 +0.4573999999999998 +0.9814999999999996 +0.4799000000000002 +0.4861 +1.2106 +0.4349000000000003 +0.5148999999999999 +0.5297000000000001 +0.38619999999999965 +0.4407000000000001 +0.6729000000000003 +0.5084000000000004 +0.7041 +0.5884 +0.40029999999999966 +0.8726000000000003 +1.076 +0.9230999999999994 +1.0903999999999998 +0.8115000000000001 +0.9152 +1.021 +0.6974999999999998 +0.8451999999999997 +0.6897000000000002 +1.0618000000000003 +0.6692 +0.6132 +0.8756999999999997 +0.2113999999999998 +0.8002000000000002 +1.1834999999999996 +0.6540999999999997 +0.7626 +0.6069 +0.32909999999999995 +1.0596999999999999 +0.9493999999999998 +0.5350999999999999 +0.4548000000000001 +0.6444999999999999 +0.30479999999999974 +0.46430000000000016 +0.46689999999999987 +0.40390000000000015 +0.4756 +0.4772000000000003 +0.35790000000000033 +0.4542999999999999 +0.4754999999999998 +0.06150000000000011 +0.02829999999999977 +0.4232 +0.4683999999999999 +0.2065999999999999 +0.3893 +0.4392999999999998 +0.5819000000000001 +0.6002000000000001 +0.45809999999999995 +0.30810000000000004 +0.5444999999999998 +0.4529000000000001 +0.23040000000000038 +0.4399000000000002 +0.7086000000000001 +0.7821000000000002 +0.7513999999999998 +0.3330000000000002 +0.28310000000000013 +0.5711999999999997 +0.46460000000000035 +0.28259999999999996 +0.4518 +0.31979999999999986 +0.48419999999999996 +0.44589999999999996 +0.6137999999999999 +0.4918 +0.4855999999999998 +0.10400000000000009 +0.45879999999999965 +0.5247999999999999 +0.28039999999999976 +0.23089999999999966 +0.45520000000000005 +0.45689999999999964 +0.4681000000000002 +0.3571 +0.45840000000000014 +0.4708999999999999 +0.4649000000000001 +0.4641000000000002 +0.1881999999999997 +0.9818000000000002 +0.9380000000000002 +1.0394999999999999 +1.0673 +0.8975 +0.8717000000000001 +0.8339000000000003 +1.104 +1.0913000000000004 +0.5414000000000003 +1.0086 +0.8611999999999997 +0.7222999999999997 +1.1046 +0.3809999999999998 +0.9510999999999998 +1.0034999999999998 +0.9277000000000002 +0.7656999999999998 +0.6736 +0.8216999999999999 +1.0885999999999996 +0.9340999999999999 +0.8821999999999997 +0.9558999999999997 +0.4485000000000001 +0.8527999999999998 +0.5933000000000002 +0.7240000000000002 +0.8214999999999999 +0.9882 +0.9798 +0.8652000000000002 +0.8840999999999997 +1.0791 +0.6286999999999998 +0.8082000000000003 +0.9434 +0.7238000000000002 +0.7283 +1.0698000000000003 +1.0594999999999999 +1.0183 +1.0648999999999997 +1.0707 +1.0208 +0.8038000000000003 +0.8281999999999998 +1.1619999999999995 +0.9142999999999999 +1.1459000000000001 +0.9198 +0.8519999999999999 +0.9837000000000002 +0.8740999999999999 +0.9171 +0.8954 +0.9540000000000002 +0.9433999999999996 +0.7272999999999996 +0.7277 +0.7709000000000001 +0.9423000000000004 +0.9297 +1.0530999999999997 +1.0387 +1.0564 +0.3675999999999999 +1.0644 +0.8935 +0.8980999999999999 +0.8677999999999999 +1.0812 +0.5942000000000003 +1.0490999999999997 +0.8499999999999996 +0.9022000000000001 +0.9289000000000001 +0.8957999999999999 +0.4176000000000002 +0.9081999999999999 +1.0065999999999997 +0.8079000000000001 +0.6840000000000002 +0.8409000000000004 +0.8757000000000001 +0.6960999999999999 +0.7190000000000003 +0.3731 +0.5215000000000001 +0.38470000000000004 +0.7538999999999998 +0.9159999999999999 +0.8327 +0.9420999999999999 +1.0034999999999998 +0.7549999999999999 +0.6640000000000001 +0.8180999999999998 +0.8299000000000003 +0.7751000000000001 +0.7904999999999998 +0.7670000000000003 +0.6919999999999997 +0.6305999999999998 +0.7228999999999997 +0.6366 +0.9638999999999998 +0.8032000000000004 +0.8130999999999999 +0.8561000000000001 +0.9771000000000001 +0.6221999999999999 +0.9236999999999997 +0.6898 +0.6765000000000003 +1.0513999999999997 +0.8007 +0.8388 +0.6858999999999997 +0.7890000000000001 +0.7412000000000001 +0.6919 +0.6142000000000003 +0.6814 +0.8007999999999997 +0.3994 +0.013100000000000112 +0.6901000000000002 +0.6205000000000003 +0.1555000000000002 +0.1431 +0.3860999999999999 +0.7916999999999996 +0.5397000000000003 +0.585 +0.7202999999999999 +0.3218000000000001 +0.5344000000000002 +0.5066000000000002 +0.7364999999999999 +0.2138 +0.7078000000000002 +0.23309999999999986 +0.4692000000000003 +0.1271 +0.7892000000000001 +0.7635999999999998 +0.5736999999999997 +0.6275 +0.41839999999999966 +0.7803 +0.8253000000000004 +0.6978999999999997 +0.3100999999999998 +0.5642 +0.7133000000000003 +0.5623 +0.48329999999999984 +0.7187999999999999 +0.7757999999999998 +0.4428000000000001 +0.4285000000000001 +0.9247999999999998 +0.6981000000000002 +0.6223999999999998 +0.37349999999999994 +0.5931000000000002 +0.786 +0.762 +0.7248999999999999 +0.7705000000000002 +0.9238999999999997 +0.6400000000000001 +0.5575999999999999 +0.6587000000000001 +0.6846999999999999 +0.5819999999999999 +0.6603999999999997 +0.8500999999999999 +0.7378 +0.79 +0.6698 +0.6631 +0.6962999999999999 +0.4681000000000002 +0.38980000000000015 +0.6166 +0.5571999999999999 +0.5233000000000003 +0.49629999999999974 +0.6780999999999997 +0.12250000000000005 +1.0070999999999999 +0.9861 +1.0082999999999998 +0.9373999999999998 +0.6954000000000002 +0.7222 +0.5361000000000002 +0.7012999999999998 +0.6629 +0.6741000000000001 +0.6341000000000001 +0.8386 +0.8959999999999999 +0.8068999999999997 +0.7378 +0.7544 +0.8224 +0.7254999999999998 +0.6233 +0.7511000000000001 +0.8112999999999997 +0.7807999999999997 +0.6985999999999999 +0.9636999999999998 +0.7925 +0.7796000000000003 +0.7484999999999999 +0.6696 +0.6476000000000002 +0.5314999999999999 +0.46130000000000004 +0.7880000000000003 +0.5007999999999999 +0.6059999999999999 +0.8211999999999997 +0.782 +0.15790000000000015 +0.7953000000000001 +0.35340000000000016 +0.3652000000000002 +0.21709999999999985 +0.6181999999999999 +0.8249000000000004 +1.0059 +0.7818 +0.7855000000000003 +0.7098999999999998 +0.6492999999999998 +0.9251 +1.0223999999999998 +0.8376000000000001 +0.9451999999999998 +0.3741000000000003 +0.9259 +0.8948999999999998 +0.8978000000000002 +0.8614999999999999 +0.6198999999999999 +0.9016000000000002 +0.7229000000000001 +0.7719 +0.7681 +0.9159999999999999 +0.5720999999999998 +0.45409999999999995 +0.7328999999999999 +0.38329999999999975 +0.7439999999999998 +0.9090000000000003 +0.6747000000000001 +0.8233000000000001 +0.48360000000000003 +0.883 +0.7710000000000004 +0.6517999999999997 +0.7465999999999999 +0.7984 +0.7107000000000001 +0.7418999999999998 +0.7189999999999999 +0.7246000000000001 +0.7052999999999998 +0.702 +0.7252999999999998 +0.7946 +0.7892000000000001 +0.7599 +0.7403 +0.6275 +0.7353000000000001 +0.8608000000000002 +0.7866999999999997 +0.9701 +0.9784999999999999 +0.4586999999999999 +0.9624000000000001 +0.9765000000000001 +0.4487000000000001 +0.7437999999999998 +0.9444999999999997 +0.9182000000000001 +0.9834 +0.7225000000000001 +0.827 +0.4017000000000004 +0.8944000000000001 +0.4140999999999999 +0.6877999999999997 +0.8699999999999997 +0.7917999999999998 +0.5506000000000002 +0.8348 +0.7035 +0.7837000000000001 +0.7328000000000001 +0.6839 +0.7526999999999999 +0.8139999999999996 +0.6946000000000003 +0.7587999999999999 +0.9311000000000003 +0.5678999999999998 +0.8188 +0.7161 +0.7970000000000002 +0.7041000000000004 +0.7452999999999999 +0.5333000000000001 +0.7869000000000002 +0.7844000000000002 +0.5405000000000002 +0.6890999999999998 +0.7444999999999999 +0.7109000000000001 +0.16869999999999985 +0.8418999999999999 +0.7486999999999999 +0.3732000000000002 +0.4177000000000004 +0.5707999999999998 +0.2671999999999999 +0.6154000000000002 +0.4772000000000003 +0.8340999999999998 +0.6020999999999996 +0.5467 +0.367 +0.9199000000000002 +0.5787999999999998 +0.7479 +0.6422000000000003 +0.7883 +0.2365999999999997 +0.6728999999999998 +0.47189999999999976 +0.4843000000000002 +0.17669999999999986 +0.5306000000000002 +0.2797999999999998 +0.7478000000000002 +0.3482000000000003 +0.4607000000000001 +0.41869999999999985 +0.9183999999999997 +0.9819 +0.9487999999999999 +0.9450000000000003 +0.9381999999999997 +0.7513999999999998 +0.7519 +0.5773000000000001 +0.8842999999999996 +0.7751999999999999 +0.5649000000000002 +0.5662000000000003 +0.6636000000000002 +0.5436999999999999 +0.4577 +1.0389 +1.1561 +0.9413 +0.9295999999999998 +1.1953 +1.0385 +0.9977999999999998 +0.8855999999999997 +0.7117 +0.8355999999999999 +0.9847000000000001 +0.96 +1.1301 +1.0688999999999997 +1.0448 +1.0097 +0.9424000000000001 +0.9612000000000003 +0.5457999999999998 +0.7799 +0.9998 +1.1562999999999999 +1.0673999999999997 +0.9600999999999997 +0.9307000000000003 +0.8851 +1.3080000000000003 +1.0382000000000002 +1.0238 +0.8523999999999998 +1.1679999999999997 +0.8278000000000003 +1.5402 +0.9154 +0.9060000000000001 +1.1528 +1.0760999999999998 +1.0840999999999998 +1.0307 +1.1492999999999998 +0.9899 +1.2031 +0.7414000000000001 +0.6770999999999998 +0.8241 +0.911 +1.0314 +1.2242000000000002 +1.1683 +0.9489000000000001 +1.1016 +0.9571000000000001 +1.1395 +0.9293 +0.9837999999999996 +0.8039999999999998 +1.2056 +0.9161999999999999 +0.8102 +0.863 +1.1564999999999999 +0.8490000000000002 +0.8553000000000002 +0.7759999999999998 +0.9920999999999998 +0.33009999999999984 +0.9152 +0.8026 +0.9247999999999998 +0.3355999999999999 +0.6968000000000001 +0.5487000000000002 +0.3774000000000002 +0.5453000000000001 +0.8304 +0.6305999999999998 +0.7339000000000002 +0.37650000000000006 +0.835 +0.26770000000000005 +0.4335 +0.7182999999999997 +0.8514999999999997 +0.8403999999999998 +0.5998999999999999 +0.3849 +1.2054 +0.5480999999999998 +0.9682 +0.8003999999999998 +1.1591 +1.2054999999999998 +1.1781000000000001 +0.5047999999999999 +1.0951999999999997 +0.8848000000000003 +1.2357 +0.3533999999999997 +0.9234 +1.0896999999999997 +1.1143999999999998 +0.1615000000000002 +1.2107 +0.9359999999999999 +0.7871000000000001 +0.4631999999999996 +1.1092 +1.1971000000000003 +1.1707999999999998 +1.129 +1.1888 +0.2873000000000001 +1.0532000000000004 +0.7883 +0.7908 +1.142 +0.9682999999999997 +0.22809999999999997 +1.0145 +0.6517 +0.4730000000000003 +0.4845999999999999 +0.22949999999999982 +0.8489 +1.1128 +1.0818000000000003 +0.9676 +0.9763999999999999 +0.7802000000000002 +0.9567999999999999 +1.1043000000000003 +0.7741000000000002 +0.6046 +0.7465999999999999 +0.9899 +1.1097000000000001 +0.9892000000000003 +0.8856000000000002 +0.7155 +1.0838999999999999 +0.4155000000000002 +0.9253999999999998 +1.0879000000000003 +0.6968999999999999 +1.0430000000000001 +0.5318999999999998 +0.6816 +1.0652 +0.9724999999999997 +0.9925000000000002 +0.42910000000000004 +0.6623999999999999 +1.0026000000000002 +0.45310000000000006 +0.5359000000000003 +0.915 +0.8779999999999997 +0.2791999999999999 +0.9207999999999998 +0.528 +1.0702000000000003 +1.169 +1.0749 +0.6949000000000001 +0.7884000000000002 +0.7833000000000001 +0.6063000000000001 +0.32699999999999996 +0.9893000000000001 +0.9460999999999999 +0.9276 +0.4631000000000003 +0.7171999999999996 +0.7204000000000002 +0.7663000000000002 +0.1748000000000003 +0.5312000000000001 +0.8269000000000002 +1.1473 +0.6275000000000004 +0.9781 +0.4778000000000002 +0.46920000000000006 +0.5359999999999998 +0.6966000000000001 +0.8479000000000001 +0.9481000000000002 +0.3797999999999999 +0.8445999999999998 +0.9508000000000001 +0.6821999999999999 +1.0386000000000002 +0.6762000000000001 +0.6440000000000001 +0.9325000000000001 +0.8250000000000002 +0.8336999999999999 +0.38870000000000005 +0.5167000000000002 +0.37619999999999987 +0.17559999999999976 +0.43100000000000005 +0.7374 +1.0179 +0.9154999999999998 +0.6951999999999998 +0.9847999999999999 +0.7725 +0.7052999999999998 +0.9402999999999997 +0.5493999999999999 +0.16800000000000015 +0.6554000000000002 +1.0192 +1.0573000000000001 +0.6057999999999999 +1.1349 +1.0789999999999997 +0.7297000000000002 +0.09550000000000036 +0.9672999999999998 +0.2610999999999999 +0.899 +0.8761999999999999 +0.9641000000000002 +0.9177000000000004 +0.4599000000000002 +0.9876 +0.3218000000000001 +0.2881 +0.07939999999999969 +0.4721000000000002 +1.0936 +0.37749999999999995 +0.9895 +1.2584 +0.7366000000000001 +0.9778000000000002 +1.052 +0.7155 +0.9224999999999999 +0.5640999999999998 +0.8812000000000002 +0.8874 +1.065 +1.0069 +0.8586 +0.9217 +0.6656 +0.8803000000000001 +0.827 +1.1816 +0.9023999999999996 +0.7842000000000002 +1.1764000000000001 +0.9823 +0.7845000000000004 +0.9701 +1.0034999999999998 +0.9849999999999999 +0.7688000000000001 +0.8980000000000001 +0.5994999999999999 +1.0784000000000002 +1.0082 +0.9177000000000004 +0.8996 +0.9371999999999998 +0.6774999999999998 +0.8424 +1.0903 +1.0324999999999998 +1.0545 +1.1414 +0.8971 +0.8123 +0.9998 +0.9935 +0.7601 +0.27249999999999996 +0.6208 +0.9227999999999996 +0.7427000000000001 +0.8966999999999996 +0.9223999999999997 +0.8719000000000001 +0.38919999999999977 +0.7638000000000003 +0.32600000000000007 +0.8982999999999999 +0.8876999999999997 +0.6669 +0.5697999999999999 +0.7605000000000004 +0.8279000000000001 +0.6071999999999997 +0.8401999999999998 +0.7889999999999997 +0.7458 +0.9407000000000001 +0.8672 +0.8231999999999999 +1.0185 +0.9285000000000001 +0.7429000000000001 +0.8715999999999999 +0.5423 +0.7901000000000002 +0.7308000000000003 +0.9165000000000001 +0.7145000000000001 +0.7525999999999997 +0.6384999999999996 +0.7605999999999997 +1.0042 +1.1268000000000002 +1.513 +0.7530999999999999 +0.8745000000000003 +0.9188000000000001 +0.8001999999999998 +0.8331 +0.8948 +0.7969000000000004 +0.7961 +0.9533999999999998 +0.8744000000000001 +0.36370000000000013 +0.8024 +0.9571000000000001 +0.8147000000000002 +0.8401000000000001 +0.7670999999999997 +0.8170999999999999 +1.1693000000000002 +1.1665 +1.2454999999999998 +1.5044000000000004 +1.1587 +0.8363999999999998 +1.2812999999999999 +1.1318000000000001 +0.8344999999999998 +0.363 +1.0749999999999997 +1.1476000000000002 +1.0707999999999998 +1.068 +0.9683999999999999 +0.7511999999999999 +1.2705000000000002 +1.3339999999999996 +1.2666000000000004 +1.1869 +1.3981000000000003 +0.8786 +1.0211000000000001 +1.0547 +1.0877 +0.5013000000000001 +1.1173000000000002 +0.9476 +0.9040000000000004 +0.6743000000000001 +1.0984999999999996 +1.2869000000000002 +1.0964 +1.0575 +1.4616000000000002 +0.7499000000000002 +1.0525000000000002 +0.9612000000000003 +0.8174999999999999 +0.8845000000000001 +0.992 +0.8688000000000002 +0.9491 +0.8681999999999999 +0.8808000000000002 +0.8814000000000002 +1.0907 +0.4942000000000002 +0.6750000000000003 +0.9333 +0.058800000000000185 +0.9243999999999999 +0.8805000000000001 +0.6583000000000001 +1.1103999999999998 +1.0108000000000001 +0.9483999999999999 +0.35660000000000003 +1.0437999999999996 +1.3729999999999998 +1.1772999999999998 +1.1311999999999998 +1.3352999999999997 +1.2154000000000003 +1.1686 +0.9570000000000003 +0.6742000000000004 +0.011399999999999633 +0.6703000000000001 +0.7930000000000001 +0.6316000000000002 +0.4693999999999998 +0.8737999999999997 +0.9196 +0.11359999999999992 +0.41159999999999997 +0.5651999999999999 +0.2784 +0.4590000000000001 +0.5261 +0.8764000000000003 +0.9870999999999999 +0.5143999999999997 +0.7629000000000001 +0.4903999999999997 +0.6069 +0.5419 +0.7478000000000002 +0.14929999999999977 +0.10830000000000028 +0.9920999999999998 +0.2873999999999999 +0.1532 +0.7532999999999999 +0.762 +0.8618000000000001 +0.8059000000000003 +0.36860000000000026 +0.7526999999999999 +0.8193999999999999 +1.1517999999999997 +1.0103999999999997 +0.8940000000000001 +0.6563000000000003 +0.40049999999999963 +0.18480000000000008 +0.4925999999999999 +0.25290000000000035 +0.6564000000000001 +0.02760000000000007 +0.07160000000000011 +0.014699999999999935 +0.07129999999999992 +0.7176999999999998 +1.0067999999999997 +0.07679999999999998 +0.2147000000000001 +0.21189999999999998 +0.20789999999999997 +1.0505999999999998 +0.32120000000000015 +0.7404999999999999 +0.6238999999999999 +0.6440999999999999 +0.5255999999999998 +0.19289999999999985 +0.07059999999999977 +0.10499999999999998 +0.07469999999999999 +0.12729999999999997 +0.7605 +0.3205 +0.46179999999999977 +0.8361999999999998 +0.7193999999999998 +0.7372999999999998 +0.13390000000000013 +0.6177999999999999 +0.8280000000000003 +0.7656999999999998 +0.47730000000000006 +0.03710000000000013 +0.9077000000000002 +0.5778000000000003 +0.6309999999999998 +0.27449999999999974 +0.16459999999999964 +0.11450000000000005 +0.5771999999999999 +0.39049999999999985 +0.5298000000000003 +0.4647999999999999 +0.5049000000000001 +0.6270000000000002 +0.6701999999999999 +0.08139999999999992 +0.6973000000000003 +0.7091000000000003 +0.10130000000000017 +0.7223999999999999 +0.4288000000000003 +0.4608000000000003 +0.08540000000000036 +0.6456 +0.11209999999999987 +0.8160000000000003 +0.38560000000000016 +0.44709999999999983 +0.16020000000000012 +0.20699999999999985 +0.8679000000000001 +1.3355000000000001 +0.016100000000000225 +0.03550000000000031 +0.8628999999999998 +0.8146999999999998 +0.022399999999999753 +0.5232000000000001 +0.6748000000000003 +0.02629999999999999 +0.46740000000000004 +0.2662 +0.12359999999999971 +0.2818999999999998 +0.5238 +0.4424000000000001 +0.7969000000000004 +0.24340000000000028 +0.6356000000000002 +0.7942999999999998 +0.01770000000000005 +0.9279000000000002 +0.8193999999999999 +0.8247999999999998 +0.5387999999999997 +1.0013 +0.6705000000000001 +0.3921000000000001 +1.1249000000000002 +0.9051999999999998 +1.2397000000000005 +0.8277000000000001 +0.015000000000000124 +0.33799999999999963 +0.6208 +0.3700000000000001 +0.8853 +0.23409999999999975 +0.03290000000000015 +0.8132999999999999 +0.6991 +0.4503999999999997 +1.0231000000000003 +0.3183 +0.5087000000000002 +0.1360999999999999 +0.23360000000000003 +0.4638 +0.5137 +0.3536999999999999 +0.5493000000000001 +0.4613999999999998 +0.12590000000000012 +0.5680000000000001 +0.6012 +0.5268999999999999 +0.5537999999999998 +0.013700000000000045 +0.24319999999999986 +0.31720000000000015 +0.3501000000000003 +0.6331000000000002 +0.552 +0.4259999999999997 +0.7229000000000001 +0.762 +0.5007999999999999 +0.6383999999999999 +0.40200000000000014 +0.6794000000000002 +0.007100000000000106 +0.5661 +0.20799999999999974 +0.09589999999999987 +0.03980000000000006 +0.07630000000000026 +0.13339999999999996 +0.4123999999999999 +0.19310000000000027 +0.025800000000000267 +0.00890000000000013 +0.03110000000000035 +0.2790999999999997 +0.038899999999999935 +0.17070000000000007 +0.22049999999999992 +0.015099999999999891 +0.5611999999999999 +0.24409999999999998 +0.37639999999999985 +0.5802 +0.41000000000000014 +0.03670000000000018 +0.011400000000000077 +0.17609999999999992 +0.017900000000000027 +0.4439000000000002 +0.09240000000000004 +0.01750000000000007 +0.0020999999999999908 +0.022900000000000365 +0.17120000000000024 +0.5323000000000002 +0.011200000000000099 +0.1908000000000003 +0.013299999999999867 +0.5579000000000001 +0.13229999999999986 +0.11000000000000032 +0.03100000000000014 +0.6839 +0.44030000000000014 +0.024799999999999933 +0.13009999999999966 +0.08360000000000012 +0.13500000000000023 +0.22090000000000032 +0.34509999999999996 +0.19979999999999976 +0.2751999999999999 +0.39280000000000026 +0.25639999999999974 +0.28359999999999985 +0.03270000000000017 +0.04139999999999988 +0.019300000000000317 +0.006600000000000161 +0.023100000000000342 +0.2900999999999998 +0.23720000000000008 +0.4984000000000002 +0.3708 +0.26180000000000003 +0.1477999999999997 +0.21770000000000023 +0.6297999999999999 +0.4962 +0.4516 +0.17920000000000025 +0.38580000000000014 +0.24029999999999996 +0.5433000000000003 +0.4466999999999999 +0.3826999999999998 +0.6371000000000002 +0.5497999999999998 +0.011399999999999855 +0.008500000000000174 +0.008299999999999752 +0.008399999999999963 +0.010299999999999976 +0.0259999999999998 +0.6497000000000002 +0.27520000000000033 +0.5282999999999998 +0.03080000000000016 +0.011600000000000055 +0.0038999999999997925 +0.025599999999999845 +0.010200000000000209 +0.6041000000000003 +0.6505000000000001 +0.44110000000000005 +0.24659999999999993 +0.20350000000000001 +0.5023 +0.6647000000000003 +0.045700000000000074 +0.6794000000000002 +0.5579999999999998 +0.0501999999999998 +0.15980000000000016 +0.5541 +0.11030000000000006 +0.11929999999999996 +0.5448999999999997 +0.38569999999999993 +0.0028999999999999027 +0.01529999999999987 +0.3557999999999999 +0.026299999999999768 +0.16359999999999975 +0.10720000000000018 +0.4687000000000001 +0.18640000000000034 +0.3864000000000001 +0.2817000000000003 +0.17589999999999995 +0.20740000000000025 +0.3440000000000003 +0.03810000000000002 +0.1903999999999999 +0.13629999999999987 +0.2625000000000002 +0.16430000000000033 +0.26900000000000013 +0.7016999999999998 +0.536 +0.32179999999999986 +0.28970000000000007 +0.038799999999999724 +0.02429999999999999 +0.03749999999999987 +0.13939999999999975 +0.11759999999999993 +0.012599999999999945 +0.019600000000000062 +0.32289999999999974 +0.020999999999999908 +0.008199999999999985 +0.02499999999999991 +0.02080000000000015 +0.011200000000000099 +0.0032999999999998586 +0.6198999999999999 +0.027900000000000258 +0.022299999999999986 +0.010800000000000143 +0.10999999999999988 +0.018199999999999772 +0.1589999999999998 +0.6637 +0.015800000000000036 +0.33999999999999986 +0.5894000000000004 +0.6614000000000004 +0.9648000000000003 +0.6495000000000002 +0.02259999999999973 +0.5296000000000003 +0.10279999999999978 +0.5055000000000001 +0.03510000000000035 +0.023100000000000342 +0.040300000000000225 +0.6274000000000002 +0.017199999999999882 +0.24380000000000024 +0.6661000000000001 +0.28480000000000016 +0.020099999999999785 +0.010499999999999954 +0.0524 +0.010000000000000231 +0.6516000000000002 +0.01429999999999998 +0.029300000000000104 +0.019899999999999807 +0.008999999999999897 +0.028499999999999748 +0.024799999999999933 +0.7394000000000003 +0.04610000000000003 +0.048100000000000254 +0.039699999999999847 +0.3676999999999997 +0.5483000000000002 +0.8418000000000001 +0.05420000000000025 +0.7373000000000003 +0.43530000000000024 +0.4992000000000001 +0.04599999999999982 +0.37840000000000007 +0.2445999999999997 +0.4655 +0.047499999999999876 +0.0394000000000001 +0.6848999999999998 +0.7704 +0.3456999999999999 +0.2326999999999999 +0.0490999999999997 +0.40779999999999994 +0.02939999999999987 +0.6073 +0.13960000000000017 +0.14320000000000022 +0.09189999999999987 +0.3323999999999998 +0.5573999999999999 +0.24490000000000034 +0.6010000000000004 +0.011500000000000288 +0.6000999999999999 +0.02320000000000011 +0.24070000000000036 +0.04349999999999987 +0.20640000000000036 +0.08779999999999966 +0.7018 +0.355 +0.00649999999999995 +0.17989999999999995 +0.4348000000000001 +0.019400000000000084 +0.6466000000000003 +0.07910000000000039 +0.03329999999999966 +0.4474 +0.6284999999999998 +0.19559999999999977 +0.1644000000000001 +0.5215000000000001 +0.7014 +0.2974000000000001 +0.24360000000000026 +0.7130999999999998 +0.04590000000000005 +0.4011 +0.3281999999999998 +0.11319999999999997 +0.4479000000000002 +0.5111999999999997 +0.508 +0.07030000000000003 +0.5630999999999999 +0.052999999999999936 +0.21700000000000008 +0.7084999999999999 +0.7139000000000002 +0.5552000000000001 +0.006599999999999717 +0.26549999999999985 +0.010600000000000165 +0.010299999999999976 +0.009200000000000097 +0.016599999999999948 +0.5287000000000002 +0.011200000000000099 +0.3474999999999997 +0.2772999999999999 +0.02770000000000028 +0.06379999999999963 +0.3624999999999998 +0.4811000000000001 +0.6010999999999997 +0.6316999999999999 +0.0250999999999999 +0.3106 +0.04159999999999986 +0.10789999999999988 +0.008899999999999686 +0.09940000000000015 +0.019000000000000128 +0.34430000000000005 +0.4129999999999998 +0.09889999999999999 +0.40329999999999977 +0.1423000000000001 +0.07180000000000009 +0.06840000000000002 +0.4153000000000002 +0.47330000000000005 +0.21259999999999968 +0.3651 +0.5630000000000002 +0.020000000000000018 +0.24529999999999985 +0.5199999999999996 +0.3389000000000002 +0.8291 +0.5401000000000002 +0.7473999999999998 +0.11339999999999995 +0.14109999999999978 +0.05500000000000016 +0.3005 +0.36149999999999993 +0.06309999999999993 +0.5396000000000001 +0.010299999999999976 +0.5598000000000001 +0.12480000000000024 +0.33440000000000003 +0.6128 +0.1755 +0.29190000000000005 +0.6093999999999999 +0.06869999999999976 +0.37219999999999986 +0.20009999999999994 +0.0479999999999996 +0.09370000000000012 +0.0383 +0.21079999999999988 +0.23470000000000013 +0.05840000000000023 +0.5267 +0.3578999999999999 +0.3190999999999997 +0.3127 +0.28980000000000006 +0.0013999999999998458 +0.021500000000000075 +0.5085999999999999 +0.006599999999999717 +0.28889999999999993 +0.03189999999999982 +0.18660000000000032 +0.48760000000000003 +0.5987 +0.5912999999999999 +0.3908999999999998 +0.4196 +0.007899999999999796 +0.025599999999999845 +0.01650000000000018 +0.24350000000000005 +0.17189999999999994 +0.3317999999999999 +0.43199999999999994 +0.5813000000000001 +0.22109999999999985 +0.039899999999999824 +0.028000000000000025 +0.31800000000000006 +0.08650000000000002 +0.24209999999999976 +0.06840000000000002 +0.011499999999999844 +0.37440000000000007 +0.056599999999999984 +0.20900000000000007 +0.4384000000000001 +0.5406 +0.6297000000000001 +0.006900000000000128 +0.0007999999999999119 +0.006799999999999695 +0.01200000000000001 +0.36370000000000013 +0.0754999999999999 +0.5427999999999997 +0.0019999999999997797 +0.3629000000000002 +0.3048000000000002 +0.05859999999999976 +0.020700000000000163 +0.008099999999999996 +0.4203000000000001 +0.681 +0.06910000000000016 +0.017600000000000282 +0.0045999999999999375 +0.0015999999999998238 +0.1395000000000004 +0.017599999999999838 +0.014399999999999746 +0.1785000000000001 +0.005299999999999638 +0.0049000000000001265 +0.08919999999999995 +0.008100000000000218 +0.5629 +0.01770000000000005 +0.3651 +0.006699999999999928 +0.01130000000000031 +0.06889999999999974 +0.24219999999999997 +0.21609999999999996 +0.5678999999999998 +0.4910000000000001 +0.5886 +0.4317000000000002 +0.10119999999999996 +0.3623999999999996 +0.7032000000000003 +0.028299999999999992 +0.2801999999999998 +0.18049999999999988 +0.6947000000000001 +0.2254999999999998 +0.7229000000000001 +0.6966000000000001 +0.5766 +0.35409999999999986 +0.09219999999999962 +0.48429999999999973 +0.46399999999999997 +0.11780000000000035 +0.25340000000000007 +0.013099999999999667 +0.32699999999999996 +0.4430999999999998 +0.27449999999999974 +0.0037000000000002586 +0.3805999999999998 +0.43869999999999987 +0.15770000000000017 +0.32030000000000003 +0.49219999999999997 +0.528 +0.3929999999999998 +0.41149999999999975 +0.4918 +0.5154999999999998 +0.13890000000000002 +0.01540000000000008 +0.02750000000000008 +0.0039000000000002366 +0.4569000000000001 +0.3809999999999998 +0.5355000000000003 +0.13500000000000023 +0.29910000000000014 +0.37760000000000016 +0.22120000000000006 +0.38969999999999994 +0.03499999999999992 +0.2587999999999999 +0.45500000000000007 +0.5640999999999998 +0.051899999999999835 +0.2376999999999998 +0.13070000000000004 +0.39049999999999985 +0.41910000000000025 +0.5667 +0.2096 +0.5789 +0.5238 +0.24840000000000018 +0.4062000000000001 +0.0041999999999999815 +0.03669999999999973 +0.6461999999999999 +0.2944 +0.21650000000000036 +0.00770000000000004 +0.46519999999999984 +0.3911000000000002 +0.3878999999999997 +0.41320000000000023 +0.028999999999999915 +0.5701 +0.3004000000000002 +0.2057 +0.42210000000000036 +0.5289000000000001 +0.4643999999999999 +0.06610000000000005 +0.5385 +0.3439000000000001 +0.35740000000000016 +0.2056 +0.4849000000000001 +0.4496000000000002 +0.20429999999999993 +0.5004 +0.0754999999999999 +0.20040000000000013 +0.1806000000000001 +0.1155999999999997 +0.04919999999999991 +0.19399999999999995 +0.37729999999999997 +0.5103 +0.5604 +0.4112999999999998 +0.16809999999999992 +0.25970000000000004 +0.29259999999999975 +0.12860000000000005 +0.2232000000000003 +0.23529999999999962 +0.1790999999999996 +0.43489999999999984 +0.24590000000000023 +0.056599999999999984 +0.15579999999999972 +0.49829999999999997 +0.1501999999999999 +0.0016000000000002679 +0.016799999999999926 +0.0343 +0.023399999999999643 +0.014100000000000001 +0.09010000000000007 +0.08820000000000006 +0.14029999999999987 +0.002200000000000202 +0.0015999999999998238 +0.0013000000000000789 +0.01709999999999967 +0.03190000000000026 +0.012599999999999945 +0.1694 +0.3334999999999999 +0.13960000000000017 +0.033299999999999885 +0.07610000000000028 +0.0693999999999999 +0.5647000000000002 +0.0036999999999998145 +0.6088999999999998 +0.5034999999999998 +0.007699999999999818 +0.013799999999999812 +0.5483000000000002 +0.008599999999999941 +0.010299999999999976 +0.005600000000000271 +0.03169999999999984 +0.016000000000000014 +0.1600999999999999 +0.5266000000000002 +0.2997000000000001 +0.008399999999999963 +0.09579999999999966 +0.27070000000000016 +0.06430000000000025 +0.021999999999999797 +0.02839999999999998 +0.2022999999999997 +0.5327999999999999 +0.5047999999999999 +0.5802 +0.5362 +0.004699999999999704 +0.45100000000000007 +0.011200000000000099 +0.11690000000000023 +0.006400000000000183 +0.0354000000000001 +0.0230999999999999 +0.06610000000000005 +0.004400000000000404 +0.013900000000000023 +0.006899999999999906 +0.10429999999999984 +0.01849999999999996 +0.029199999999999893 +0.02980000000000027 +0.6164000000000001 +0.8443 +0.019400000000000084 +0.9213999999999998 +0.7959 +0.42500000000000027 +0.20020000000000016 +0.44049999999999967 +0.5003000000000002 +0.3275000000000001 +0.18199999999999994 +0.6358000000000001 +0.6379000000000001 +0.6762000000000001 +0.5145999999999997 +0.4596999999999998 +0.5267 +0.5484 +0.6051000000000002 +0.05600000000000005 +0.6217999999999999 +0.8096000000000001 +0.19709999999999983 +0.09149999999999991 +0.16979999999999995 +0.16659999999999986 +0.4887999999999999 +0.29959999999999987 +0.48309999999999986 +0.4889000000000001 +0.15759999999999996 +0.1166999999999998 +0.021399999999999864 +0.7758999999999996 +0.05250000000000021 +0.13050000000000006 +0.8527999999999998 +0.5268000000000002 +0.8195999999999999 +0.41049999999999986 +0.30459999999999976 +0.022699999999999942 +0.6385000000000001 +0.48870000000000013 +0.4708000000000001 +0.23740000000000006 +0.5838000000000001 +0.40700000000000003 +0.5236000000000001 +0.8051000000000004 +0.48099999999999987 +0.30459999999999976 +1.0570999999999997 +0.46340000000000003 +0.4678 +0.5082000000000004 +0.9927000000000001 +0.8886000000000003 +0.8163 +0.44419999999999993 +1.0192999999999999 +1.0951 +0.9278000000000004 +0.1549999999999998 +1.1878999999999995 +0.8811 +0.8986000000000001 +0.9537 +0.7839999999999998 +0.8799000000000001 +0.5114999999999998 +0.40490000000000004 +0.8299000000000003 +0.4338000000000002 +1.2057000000000002 +1.0605000000000002 +0.6668000000000003 +1.0541 +1.0149 +0.2347999999999999 +0.9887000000000001 +0.8566000000000003 +1.0356999999999998 +0.8471000000000002 +0.8443 +1.3039999999999998 +0.7054999999999998 +0.8832999999999998 +0.9906999999999999 +1.0255 +0.8997999999999999 +1.0405000000000002 +0.4716 +0.9283000000000001 +0.5535999999999999 +0.9866999999999999 +0.8601999999999999 +0.8761000000000001 +0.9156 +1.2142 +0.8757999999999999 +0.9297 +1.2723999999999998 +0.9333 +0.8123999999999998 +0.9045000000000001 +1.2342999999999997 +1.1627999999999998 +0.9980000000000002 +1.2853000000000003 +0.1894 +1.3376000000000001 +0.05879999999999974 +1.0768 +0.9645999999999999 +0.16069999999999984 +0.10519999999999996 +1.0932999999999997 +0.855 +0.9276 +1.2199999999999998 +1.0834000000000001 +1.0271 +0.039200000000000124 +0.02400000000000002 +0.22849999999999993 +0.005300000000000082 +0.034600000000000186 +0.007899999999999796 +0.04760000000000009 +0.1397999999999997 +0.09169999999999989 +0.03180000000000005 +0.016300000000000203 +0.04759999999999964 +0.01289999999999969 +0.38370000000000015 +0.03489999999999993 +0.039699999999999847 +0.03500000000000014 +0.5175000000000001 +0.39759999999999973 +0.10360000000000014 +0.007400000000000073 +0.04620000000000024 +0.20719999999999983 +0.4285000000000001 +0.5301 +0.35150000000000015 +0.3177000000000003 +0.6207000000000003 +0.2410000000000001 +0.4094000000000002 +0.17000000000000037 +0.5697999999999999 +0.050799999999999734 +0.21649999999999991 +0.4981 +0.07220000000000004 +0.19699999999999962 +0.15090000000000003 +0.5694000000000004 +0.3113999999999999 +0.5117000000000003 +0.6552000000000002 +0.5952999999999999 +0.03990000000000027 +0.010099999999999998 +0.4407000000000001 +0.4980000000000002 +0.2838000000000003 +0.23110000000000008 +0.3832 +0.6712000000000002 +0.5575999999999999 +0.39769999999999994 +0.7355 +0.40969999999999995 +0.08519999999999994 +0.8893999999999997 +0.1955 +0.6046 +0.44520000000000026 +0.5936000000000003 +0.6315 +0.3567 +0.7612000000000001 +0.7307000000000001 +0.46750000000000025 +0.16089999999999982 +0.5365000000000002 +0.5925000000000002 +0.6496999999999997 +0.8588 +0.7864 +0.7794000000000003 +0.3195000000000001 +0.43889999999999985 +0.4624999999999999 +0.09909999999999997 +0.37729999999999997 +0.6460000000000004 +0.5145000000000004 +0.5074000000000001 +0.8902999999999999 +0.8142 +0.6097999999999999 +0.5553999999999997 +0.5324 +0.6569000000000003 +0.9690000000000003 +0.5684999999999998 +0.5010999999999997 +0.4855999999999998 +0.33260000000000023 +0.36739999999999995 +1.1099999999999999 +0.9220000000000006 +0.5417999999999998 +1.1822000000000004 +0.9308999999999998 +1.2069999999999999 +0.8842000000000003 +0.47129999999999983 +0.8619000000000003 +0.7465999999999999 +0.8134000000000001 +0.3628999999999998 +1.0705000000000005 +0.4317000000000002 +0.8090000000000002 +0.4493999999999998 +1.2811000000000003 +1.0131999999999999 +1.2060999999999997 +0.5114000000000001 +0.7387999999999999 +0.6354000000000002 +0.8527 +0.7099000000000002 +0.7990000000000004 +0.9139999999999997 +0.7627000000000002 +1.0685000000000002 +0.9372000000000003 +0.6006999999999998 +0.5388999999999999 +1.2374 +0.6476999999999999 +0.9956999999999998 +0.34109999999999996 +0.6238000000000001 +1.0267 +0.9270999999999998 +0.9922999999999997 +1.1439000000000004 +1.1041000000000003 +0.7432000000000003 +1.2290999999999999 +0.9428000000000001 +1.0625 +1.0213999999999999 +0.9869000000000003 +0.6194999999999999 +0.7627999999999999 +1.2332999999999998 +0.7666 +1.0456000000000003 +1.0450999999999997 +0.8748 +0.9946999999999999 +0.6062000000000003 +0.9088000000000003 +0.7637 +1.0776000000000003 +0.8971999999999998 +0.9957000000000003 +1.1739999999999995 +0.6903000000000001 +0.9198 +1.0516999999999999 +0.9226000000000001 +0.9403999999999999 +0.8741000000000003 +0.6884999999999999 +0.4953000000000003 +1.2155 +1.2153000000000005 +1.2312000000000003 +1.0204 +0.9561000000000002 +1.0070999999999999 +0.9154999999999998 +0.8163999999999998 +0.9642 +0.8125999999999998 +1.0109999999999997 +0.8005 +0.6087000000000002 +1.0322999999999998 +1.1518000000000002 +0.6294 +0.6191 +0.5476000000000001 +0.6324999999999998 +1.1387999999999994 +0.7646999999999999 +0.5947 +0.7159 +0.9956999999999998 +0.9079999999999999 +1.2866 +1.1351 +1.0726999999999998 +1.1986999999999997 +1.0346000000000002 +0.7597 +1.1278000000000001 +0.5399000000000003 +0.5632999999999999 +0.4093 +0.7199 +1.0573000000000001 +1.3176999999999999 +1.0201000000000002 +1.0854999999999997 +1.3130999999999995 +0.7560000000000002 +0.6307 +0.9299 +0.9981 +0.9253 +0.9525000000000001 +0.9624999999999999 +0.9900000000000002 +1.3028000000000004 +0.7778999999999998 +1.4013000000000004 +0.6682999999999999 +0.8558000000000003 +0.8730000000000002 +0.04520000000000035 +0.5105 +0.16979999999999995 +0.2211000000000003 +0.0939000000000001 +0.43979999999999997 +0.39559999999999995 +0.4165000000000001 +0.5935000000000001 +0.10999999999999988 +0.00890000000000013 +0.023800000000000043 +0.35770000000000035 +0.5076999999999998 +0.03699999999999992 +0.01200000000000001 +0.11900000000000022 +0.12549999999999972 +0.5157000000000003 +0.7652999999999999 +0.4018999999999999 +0.6877 +0.16389999999999993 +0.08299999999999974 +0.5154000000000001 +0.7610999999999999 +0.6691000000000003 +0.5381 +0.04129999999999967 +0.21789999999999976 +0.5921000000000003 +0.4708000000000001 +0.24580000000000002 +0.5573999999999999 +0.06199999999999983 +0.6553999999999998 +0.5943 +0.5758000000000001 +0.48439999999999994 +0.1788000000000003 +0.5242 +0.5674000000000001 +0.6590000000000003 +0.5113999999999996 +0.09579999999999966 +0.1753 +0.09960000000000013 +0.9756 +0.7717 +0.8959000000000001 +0.8525 +0.29000000000000004 +0.3416999999999999 +0.7483 +0.44799999999999995 +0.496 +0.5446 +0.21760000000000002 +0.11470000000000002 +0.15200000000000014 +0.4523999999999999 +0.42330000000000023 +0.8502000000000001 +0.5489999999999999 +0.7661000000000002 +1.0469 +0.8737999999999997 +0.4953000000000003 +0.0047000000000001485 +0.0049000000000001265 +0.18100000000000005 +0.8533999999999997 +0.2461000000000002 +0.6120000000000001 +0.8254999999999999 +0.6346999999999996 +0.815 +0.7041999999999997 +0.6549 +0.17810000000000015 +0.6517 +0.3921999999999999 +0.04859999999999998 +0.6014999999999997 +0.9344999999999999 +0.6712000000000002 +0.7734000000000001 +0.3504999999999998 +0.01289999999999969 +0.5474000000000001 +0.19989999999999997 +0.08680000000000021 +0.2265999999999999 +0.31240000000000023 +0.4041999999999999 +0.565 +0.08179999999999987 +0.12979999999999992 +0.19799999999999995 +0.013500000000000068 +0.1633 +0.2650999999999999 +0.5341999999999998 +0.6571000000000002 +0.4039999999999999 +0.6701000000000001 +0.07200000000000006 +0.32410000000000005 +0.16320000000000023 +0.1288999999999998 +0.7441999999999998 +0.9064000000000001 +0.2120000000000002 +0.1983999999999999 +0.8868 +0.6709 +0.018100000000000005 +0.5996999999999999 +0.3919999999999999 +0.8108 +0.7749000000000001 +0.7120000000000002 +0.6360999999999999 +0.8085 +0.4267999999999996 +0.7010999999999998 +0.9380999999999999 +0.7166999999999999 +0.7864999999999998 +0.9390999999999998 +0.7503 +0.9074999999999998 +0.3101999999999996 +0.7738999999999998 +0.21830000000000016 +0.7214999999999998 +0.5657000000000001 +0.38169999999999993 +0.4114 +0.7972999999999999 +0.5305 +0.8540999999999999 +0.6598000000000002 +0.3912 +0.05879999999999974 +0.9613999999999998 +0.6071 +0.6894999999999998 +0.9613 +0.7674000000000003 +0.6364999999999998 +0.9855 +0.01059999999999972 +0.9986000000000002 +0.23850000000000016 +0.047800000000000065 +0.8393999999999999 +0.5123000000000002 +0.10909999999999975 +0.29990000000000006 +0.14380000000000015 +0.6449000000000003 +0.6779000000000002 +0.6082000000000001 +0.887 +0.6443999999999996 +0.3607 +0.6475 +0.3822000000000001 +0.7517 +0.8216000000000001 +0.8025000000000002 +0.8819000000000004 +0.7978000000000001 +0.3089000000000002 +0.10099999999999998 +0.9268000000000001 +0.017400000000000304 +0.6200000000000001 +0.47520000000000007 +0.5251000000000001 +0.5382000000000002 +0.5903999999999998 +0.20469999999999988 +0.3147000000000002 +0.29969999999999963 +0.06109999999999971 +0.014499999999999957 +0.8009999999999997 +0.0766 +0.042100000000000026 +0.23280000000000012 +0.15280000000000005 +0.5552999999999999 +0.28990000000000027 +0.03529999999999989 +0.5055000000000001 +0.7880000000000003 +0.02729999999999988 +0.927 +0.28200000000000003 +0.28000000000000025 +0.045500000000000096 +0.9464999999999999 +0.6946999999999997 +0.9400000000000004 +0.4062999999999999 +0.9193000000000002 +1.0064000000000002 +1.0463 +0.7603 +1.0577999999999999 +0.6528 +1.0488 +0.13750000000000018 +0.3149000000000002 +0.8797000000000001 +0.5851000000000002 +0.5273999999999996 +0.18710000000000004 +0.9828000000000001 +0.7288999999999999 +0.9708000000000001 +0.9218999999999999 +1.0538000000000003 +0.7339000000000002 +1.0457 +0.492 +0.16860000000000008 +1.0758999999999999 +0.04859999999999998 +0.6920999999999999 +0.8890000000000002 +1.0699999999999998 +0.07279999999999998 +0.9340999999999999 +0.13270000000000026 +0.4085000000000001 +0.9234999999999998 +0.8010000000000002 +0.6156000000000001 +0.3050999999999999 +0.7113 +1.0331000000000001 +0.6537999999999999 +1.0347 +1.154 +1.3125999999999998 +0.1395000000000004 +0.03710000000000013 +0.012799999999999923 +0.11680000000000001 +0.9417999999999997 +0.0972000000000004 +0.4328999999999996 +0.9058000000000002 +1.1185 +0.7664 +0.5086000000000004 +0.47950000000000026 +0.5249999999999999 +0.45020000000000016 +0.6286 +0.8363999999999998 +0.6545000000000001 +0.41910000000000025 +0.923 +0.4939999999999998 +0.7466999999999997 +1.0861 +0.21499999999999986 +1.1076000000000001 +0.4492999999999996 +1.036 +0.9603999999999999 +0.7311000000000001 +0.3695999999999997 +1.0012000000000003 +1.0821999999999998 +0.9621 +0.653 +1.1156000000000001 +1.0320999999999998 +0.25749999999999984 +1.0581 +0.5617000000000001 +1.1295000000000002 +0.8262 +1.1444999999999999 +1.1677 +1.1387 +1.0796000000000001 +0.8266 +0.9108 +0.8661999999999996 +0.7998999999999996 +0.8475000000000001 +0.6818999999999997 +0.4634999999999998 +0.6316999999999999 +0.8471000000000002 +0.010900000000000354 +0.9170000000000003 +0.5125999999999997 +0.9754999999999998 +0.8948 +0.03249999999999975 +0.7719999999999998 +0.8130000000000002 +0.6046 +0.19769999999999976 +0.8282000000000003 +1.0027 +0.9286000000000003 +0.9164999999999996 +0.17559999999999976 +0.7102999999999997 +0.4263000000000001 +0.9897 +0.6335999999999999 +0.7158000000000002 +0.9411999999999998 +0.9401999999999999 +0.28800000000000003 +0.7242999999999999 +0.14019999999999966 +0.034399999999999986 +0.43789999999999996 +0.4315000000000002 +0.9577 +0.0019000000000000128 +0.4293 +0.09800000000000031 +0.9173 +0.7713999999999999 +0.6386000000000003 +0.4315000000000002 +0.8999999999999999 +0.9634 +0.5303 +0.9019999999999997 +0.006299999999999972 +0.14239999999999986 +0.36830000000000007 +0.14550000000000018 +0.7313999999999998 +0.7282000000000002 +0.8572000000000002 +0.05699999999999994 +0.8796999999999997 +0.30390000000000006 +0.0935999999999999 +0.9493999999999998 +0.8752999999999997 +0.5307 +0.27780000000000005 +0.5344000000000002 +0.3280000000000003 +0.9885000000000002 +0.7765999999999997 +0.9436 +0.0855999999999999 +0.03810000000000002 +0.7010000000000001 +0.7005999999999997 +0.16310000000000002 +0.8205999999999998 +0.8952 +0.7496999999999998 +0.013900000000000023 +0.47050000000000036 +0.15569999999999995 +0.2841999999999998 +0.9765999999999999 +0.9645999999999999 +0.1654 +0.11789999999999967 +0.08319999999999972 +0.47060000000000013 +0.25299999999999967 +0.8022999999999998 +0.5941000000000001 +0.9728000000000003 +0.5897000000000001 +1.0063 +1.0377999999999998 +1.1221999999999999 +0.9122999999999997 +1.1555 +0.7244999999999999 +0.05999999999999961 +0.4982000000000002 +0.9948999999999999 +1.1324999999999998 +1.0516 +0.5596000000000001 +0.7640000000000002 +0.8167 +0.3369 +0.4051 +0.9168000000000003 +0.9456000000000002 +0.9463999999999997 +0.9929999999999999 +0.8412000000000002 +0.79 +0.6622999999999997 +0.7974000000000001 +1.0638 +1.0033000000000003 +1.1865 +0.9685999999999999 +1.0824000000000003 +0.5103 +0.9196000000000004 +0.6713 +0.4655999999999998 +1.0150000000000001 +0.9584999999999999 +1.0442 +0.9293999999999998 +0.8305000000000002 +0.5614999999999997 +0.9312 +1.1201999999999996 +1.0632000000000001 +0.4901 +0.056700000000000195 +0.6039999999999996 +0.9507999999999996 +0.5145 +0.6093000000000002 +1.0576999999999996 +0.9213999999999998 +0.9060999999999999 +0.9237000000000002 +0.6995999999999998 +0.8494999999999999 +1.0059 +1.0186000000000002 +0.5 +0.9900000000000002 +0.8067000000000002 +0.9840999999999998 +0.8275000000000001 +0.09829999999999994 +0.45310000000000006 +0.0016000000000000458 +0.30290000000000017 +0.38660000000000005 +0.10329999999999995 +0.24109999999999987 +0.14640000000000009 +0.14619999999999989 +0.03929999999999989 +0.3601000000000001 +0.1189 +0.08190000000000008 +0.3642000000000001 +0.23309999999999986 +0.09289999999999976 +0.352 +0.5947 +0.14800000000000013 +0.40870000000000006 +0.47540000000000004 +0.012499999999999956 +0.049100000000000144 +0.5112000000000001 +0.053400000000000336 +0.36129999999999995 +0.3129999999999997 +0.3860999999999999 +0.2770999999999999 +0.5242 +0.1999000000000002 +0.573 +0.4772000000000003 +0.6309999999999998 +0.12199999999999989 +0.09120000000000017 +0.015099999999999891 +0.6480999999999999 +0.15689999999999982 +0.02750000000000008 +0.32010000000000005 +0.23819999999999997 +0.02320000000000011 +0.018299999999999983 +0.07509999999999994 +0.10959999999999992 +0.24659999999999993 +0.4946999999999999 +0.2895000000000003 +0.278 +0.5131999999999999 +0.35340000000000016 +0.5523000000000002 +0.5756000000000001 +0.48740000000000006 +0.20340000000000003 +0.3681000000000001 +0.2780999999999998 +0.5078999999999998 +0.4333999999999998 +0.4442000000000004 +0.5202 +0.4531999999999998 +0.5228999999999999 +0.5562 +0.6804999999999999 +0.7561 +0.41270000000000007 +0.6823999999999999 +0.6324000000000001 +0.5476000000000001 +0.613 +0.15829999999999966 +0.6489000000000003 +0.7531000000000003 +0.005700000000000038 +0.5655000000000001 +0.27049999999999974 +0.3286000000000002 +0.19479999999999986 +0.6257999999999999 +0.44789999999999974 +0.08349999999999991 +0.07739999999999991 +0.05259999999999998 +0.27980000000000027 +0.5209000000000001 +0.6330999999999998 +0.4283999999999999 +0.6193 +0.1915 +1.0023 +0.05410000000000004 +0.3846999999999996 +0.6853000000000002 +0.8702000000000001 +0.24639999999999995 +0.05210000000000026 +0.058800000000000185 +0.24540000000000006 +0.28390000000000004 +0.2892000000000001 +0.03639999999999999 +0.02839999999999998 +0.11629999999999985 +0.21550000000000002 +0.15910000000000002 +0.4215 +0.3317999999999999 +0.3777999999999999 +0.2721 +0.7562000000000002 +0.4417 +0.3426999999999998 +0.9851000000000001 +0.6322000000000001 +0.9912000000000001 +0.5046000000000004 +1.3209000000000004 +1.0741999999999994 +1.1511 +0.7856999999999998 +0.782 +1.3324999999999996 +0.9535999999999998 +0.9106999999999998 +0.8441000000000001 +0.8091999999999997 +1.3283 +1.2184 +1.5684999999999998 +0.9083000000000001 +0.8513000000000002 +1.1728999999999998 +1.2675 +1.2735999999999996 +1.2537999999999996 +0.7844000000000002 +0.8569 +0.9343999999999997 +0.8832 +1.3866 +1.0871 +0.9262000000000001 +1.1879 +1.0818999999999996 +1.2245 +0.45459999999999967 +1.4632999999999998 +0.8694999999999999 +1.1700999999999997 +1.3905999999999996 +0.6753 +0.8628 +0.35989999999999966 +0.6844000000000001 +0.8372000000000002 +0.5627 +0.8485 +0.7227000000000001 +0.8081999999999998 +0.6101999999999999 +0.060799999999999965 +0.08000000000000007 +0.8765999999999998 +0.38470000000000004 +0.8752999999999997 +0.47479999999999967 +0.6531000000000002 +0.47150000000000025 +0.8483999999999998 +0.17209999999999992 +0.49029999999999996 +0.9106000000000001 +0.46819999999999995 +0.6987000000000001 +0.44589999999999996 +0.9245000000000001 +0.7677 +0.1323000000000003 +0.4218000000000002 +0.7498999999999998 +0.3600000000000003 +0.20989999999999975 +0.5375999999999999 +0.9247999999999998 +0.7504000000000004 +1.0337 +0.5558000000000001 +0.042300000000000004 +0.23219999999999974 +0.40669999999999984 +0.7160000000000002 +0.08069999999999977 +0.6612 +0.7330999999999999 +0.06919999999999993 +0.1572 +0.6119999999999997 +0.8626 +0.4133 +0.40580000000000016 +0.6682000000000001 +0.0129999999999999 +0.049900000000000055 +0.6166999999999998 +0.6280999999999999 +0.03529999999999989 +0.012799999999999923 +0.5492999999999997 +0.6438999999999999 +0.5307 +0.0783999999999998 +0.47140000000000004 +0.9123000000000001 +0.4373 +0.19779999999999998 +0.8771 +0.14270000000000005 +0.6164999999999998 +0.6528 +0.5958999999999999 +0.01540000000000008 +0.01969999999999983 +0.9091 +0.7103999999999999 +0.4790000000000001 +0.8799999999999999 +0.8674000000000004 +0.7218 +0.4556 +0.3534999999999999 +0.38969999999999994 +0.15710000000000024 +0.3762000000000003 +0.04809999999999981 +0.4394 +0.7221000000000002 +0.07769999999999966 +0.2702 +0.5194999999999999 +0.33799999999999963 +0.8319999999999999 +0.5683000000000002 +0.4108999999999998 +0.4158999999999997 +0.21760000000000002 +0.7607000000000004 +0.7401999999999997 +0.11229999999999984 +0.38680000000000003 +1.1522000000000001 +0.4638 +0.4636 +0.9746999999999999 +1.1191999999999998 +0.1629999999999998 +0.6593 +0.718 +0.19630000000000036 +0.1503000000000001 +1.0369000000000002 +0.5043000000000002 +0.46740000000000004 +0.07939999999999992 +0.29349999999999987 +0.49060000000000015 +0.5899000000000001 +1.0137999999999998 +0.8325 +0.32299999999999995 +0.5678000000000001 +0.7631999999999999 +0.4956999999999998 +0.8175000000000003 +0.6052 +0.37449999999999983 +0.7509000000000001 +0.1261000000000001 +0.11520000000000019 +0.10429999999999984 +0.009500000000000064 +0.47860000000000014 +0.18950000000000022 +0.14690000000000003 +0.41979999999999995 +0.4554 +0.4023000000000003 +0.5175999999999998 +0.5602999999999998 +0.5044 +0.5178000000000003 +0.42259999999999964 +0.9689000000000001 +0.7074000000000003 +1.1002999999999998 +0.8592999999999997 +0.4207000000000001 +0.6461000000000001 +1.0713 +1.0086999999999997 +0.26649999999999974 +0.6077000000000004 +0.3820000000000001 +0.8221000000000003 +0.9289000000000001 +1.0581000000000005 +0.6972999999999998 +1.1144999999999996 +0.7628999999999997 +0.7063000000000001 +0.1835 +0.6482999999999999 +0.9470000000000001 +0.43579999999999997 +0.22239999999999993 +0.512 +0.6536 +0.6193000000000002 +1.0848 +1.0541 +0.8671000000000002 +0.23459999999999992 +0.9197000000000002 +1.3635000000000002 +0.39190000000000014 +0.6459999999999999 +0.4428000000000001 +0.4144000000000001 +0.6295000000000002 +0.5442999999999998 +0.40900000000000025 +1.0434999999999999 +0.09119999999999973 +0.9144999999999999 +0.8811999999999998 +0.6711 +0.8792 +0.5814999999999997 +0.9739 +0.8688000000000002 +0.6947000000000001 +0.8614999999999999 +0.7081 +1.1008000000000004 +0.10370000000000035 +0.12460000000000004 +0.23519999999999985 +0.15549999999999997 +0.1600999999999999 +0.3835000000000002 +0.2570000000000001 +0.23980000000000024 +0.11419999999999986 +0.0246000000000004 +0.1817000000000002 +1.1139000000000001 +0.7345999999999999 +0.3605999999999998 +0.02159999999999984 +0.42589999999999995 +0.3373000000000004 +0.5367999999999999 +0.03980000000000006 +0.6949000000000001 +0.3285 +0.5056000000000003 +1.1242 +1.3013999999999997 +0.6086999999999998 +0.49049999999999994 +1.2684000000000002 +0.7313000000000001 +0.6638999999999999 +0.19629999999999992 +0.5303 +0.9855999999999998 +1.1503 +0.34230000000000027 +0.07140000000000013 +0.5744000000000002 +0.38850000000000007 +1.0939 +1.0073000000000003 +0.21579999999999977 +0.8376000000000001 +0.3005 +0.6909999999999998 +0.6827000000000001 +0.7123999999999997 +0.9015999999999997 +1.0051 +0.9200000000000004 +1.0404999999999998 +0.8896999999999999 +0.4828000000000001 +0.24770000000000003 +0.14460000000000006 +0.017600000000000282 +0.39369999999999994 +0.27859999999999996 +0.5325000000000002 +0.3496999999999999 +0.14370000000000038 +0.04369999999999985 +0.7738 +0.21870000000000012 +1.1309 +0.5261 +0.7696999999999998 +0.5551999999999997 +1.1304000000000003 +0.5261999999999998 +0.3393999999999999 +0.3155999999999999 +0.1783999999999999 +1.1324 +0.6294 +0.15119999999999978 +0.9037999999999999 +1.1219999999999999 +0.5111999999999997 +0.8215000000000003 +0.12850000000000028 +0.6683999999999997 +0.1564000000000001 +0.07040000000000024 +0.04459999999999997 +0.5718999999999999 +0.9217000000000004 +0.29239999999999977 +1.1430999999999996 +1.3485 +0.6256999999999997 +0.2732999999999999 +0.019000000000000128 +0.7928999999999999 +0.3138000000000001 +0.8830999999999998 +0.5457000000000001 +0.6873999999999998 +0.7472999999999996 +0.7164999999999999 +1.0657999999999999 +0.19229999999999992 +0.14890000000000025 +0.2803 +0.9544000000000001 +0.8877000000000002 +1.0128 +0.6230000000000002 +0.6773000000000002 +0.13429999999999964 +0.11970000000000036 +0.4918 +0.021300000000000097 +0.7292000000000001 +0.011800000000000033 +0.6832000000000003 +0.027800000000000047 +0.9295999999999998 +1.0322999999999998 +0.02330000000000032 +0.019600000000000062 +0.041100000000000136 +0.3407 +0.6991999999999998 +0.6917 +0.1372 +1.2146 +0.9066000000000001 +0.9731999999999998 +0.7942999999999998 +1.1259000000000006 +0.137 +0.5411000000000001 +0.6883999999999997 +0.6908999999999996 +1.1567999999999996 +0.2474000000000003 +1.2163000000000004 +1.2410999999999999 +0.6396999999999999 +0.6631 +0.3059000000000003 +1.1005000000000003 +0.41670000000000007 +0.39819999999999967 +0.6019000000000001 +0.5514000000000001 +0.2845 +0.7911000000000001 +0.5905999999999998 +0.9981 +0.6678999999999999 +0.5304000000000002 +0.4777 +0.7345999999999999 +0.7554000000000003 +0.7772000000000001 +0.9933000000000001 +0.347 +0.8332999999999999 +1.0367000000000002 +0.8083 +0.6941999999999999 +0.6873 +0.6421000000000001 +0.49540000000000006 +0.9451999999999998 +0.2704 +0.24960000000000004 +0.37570000000000014 +0.6385000000000001 +0.7961999999999998 +0.3694000000000002 +0.6688000000000001 +0.8393999999999999 +0.2549000000000001 +0.4852999999999996 +0.9441999999999999 +0.6534 +1.0059999999999998 +0.5310999999999999 +0.7599 +0.0737000000000001 +0.3508 +0.7025000000000001 +0.9327999999999999 +0.7056999999999998 +0.5025 +0.7357 +0.7294 +0.2801 +0.33219999999999983 +0.9979999999999998 +0.7161999999999997 +0.6212 +1.1262000000000003 +0.9164000000000003 +0.8573 +1.2541999999999995 +0.8476000000000004 +0.7880000000000003 +1.1961 +0.8239999999999998 +0.28710000000000013 +0.395 +0.5055999999999998 +0.8439000000000001 +0.8525000000000005 +0.6566000000000001 +1.0778000000000003 +0.9998999999999998 +1.1281000000000003 +1.3014999999999999 +0.9546999999999999 +0.6606000000000001 +0.9960999999999998 +0.17410000000000014 +0.5196999999999998 +0.6017000000000001 +0.5543 +0.33830000000000027 +0.6789999999999998 +0.31279999999999974 +0.6139000000000001 +0.46620000000000017 +0.5981999999999998 +0.2467999999999999 +0.6417000000000002 +0.43610000000000015 +0.009799999999999809 +0.46809999999999974 +0.7248999999999999 +0.8005999999999998 +0.6896 +1.2744 +0.043299999999999894 +0.5965000000000003 +0.47609999999999975 +0.5712000000000002 +0.8924000000000003 +0.42979999999999974 +0.24719999999999986 +0.7821000000000002 +0.1806000000000001 +0.16929999999999978 +0.7301000000000002 +0.5800999999999998 +0.06040000000000001 +0.1301000000000001 +0.28770000000000007 +0.08519999999999994 +0.5998999999999999 +0.23340000000000005 +0.7963 +0.5792999999999999 +0.3952 +0.5848999999999998 +0.5335999999999999 +0.8031000000000001 +0.6778 +0.3809 +0.6429 +0.9445999999999999 +0.6907999999999999 +0.6745000000000001 +0.03569999999999984 +0.6625000000000001 +0.06279999999999974 +0.27920000000000034 +0.6515 +0.6919 +0.5984000000000003 +0.3402000000000003 +0.3915000000000002 +0.5556999999999999 +0.6829999999999998 +0.7614999999999998 +0.07860000000000023 +0.5648999999999997 +0.00790000000000024 +0.20220000000000038 +0.16900000000000004 +0.12539999999999996 +0.5836999999999999 +0.02770000000000028 +0.0411999999999999 +0.03520000000000012 +0.009000000000000341 +0.3250000000000002 +0.5773999999999999 +0.379 +0.5470999999999999 +0.2197 +0.6087000000000002 +0.6208 +0.05669999999999975 +0.6454 +0.6058000000000003 +0.38649999999999984 +0.6295999999999999 +0.4759000000000002 +0.6949000000000001 +0.4171 +0.20230000000000015 +0.051000000000000156 +0.023299999999999876 +0.5072000000000001 +0.007600000000000051 +0.0036000000000000476 +0.4700000000000002 +0.40549999999999997 +0.40969999999999995 +0.0354000000000001 +0.03810000000000002 +0.3825999999999996 +0.05929999999999991 +0.5004 +0.4874999999999998 +0.3096000000000001 +0.25550000000000006 +0.005800000000000249 +0.5760999999999998 +0.4445999999999999 +0.10230000000000006 +0.037599999999999856 +0.31789999999999985 +0.45100000000000007 +0.00990000000000002 +0.0259999999999998 +0.01880000000000015 +0.8127 +0.5192999999999999 +0.10789999999999988 +0.8204999999999996 +0.7556000000000003 +0.6036000000000001 +0.21879999999999988 +0.3294999999999999 +0.6947999999999999 +0.07920000000000016 +0.19959999999999978 +0.015100000000000335 +0.6599999999999997 +0.6092 +0.4310999999999998 +0.2262000000000004 +0.31769999999999987 +0.008500000000000174 +0.10309999999999997 +0.061799999999999855 +0.33950000000000014 +0.6351999999999998 +0.4934000000000003 +0.04019999999999957 +0.40759999999999996 +0.5618000000000003 +0.17220000000000013 +0.30820000000000025 +0.36339999999999995 +0.7404000000000002 +0.30420000000000025 +0.021299999999999653 +0.20299999999999985 +0.25139999999999985 +0.6561999999999997 +0.0235000000000003 +0.016599999999999948 +0.6359000000000004 +0.5333999999999999 +0.5701999999999998 +0.37939999999999996 +0.15730000000000022 +0.6061000000000001 +0.43199999999999994 +0.6337000000000002 +0.6297000000000001 +0.6397999999999997 +0.42479999999999984 +0.6429 +0.28100000000000014 +0.030100000000000016 +0.43579999999999997 +0.18799999999999972 +0.2549000000000001 +0.01440000000000019 +0.4040999999999997 +0.07030000000000003 +0.6400000000000001 +0.08020000000000005 +0.4846999999999997 +0.4396 +0.6994000000000002 +0.14539999999999997 +0.5815999999999999 +0.22199999999999998 +0.556 +0.041300000000000114 +0.4551000000000003 +0.3443999999999998 +0.4376000000000002 +0.49529999999999985 +0.06289999999999996 +0.2549000000000001 +0.18579999999999997 +0.6055999999999999 +0.05520000000000014 +0.10709999999999997 +0.19230000000000036 +0.7018 +0.5928 +0.49960000000000004 +0.1926000000000001 +0.013399999999999856 +0.0383 +0.5996000000000001 +0.02499999999999991 +0.6196999999999999 +0.05920000000000014 +0.03630000000000022 +0.4485000000000001 +0.6328 +0.11839999999999984 +0.03180000000000005 +0.5874999999999999 +0.18630000000000013 +0.16420000000000012 +0.34529999999999994 +0.22350000000000003 +0.6936 +0.8786 +0.0495000000000001 +0.012599999999999945 +0.1069 +0.36099999999999977 +0.26869999999999994 +0.5095000000000001 +0.4892000000000003 +0.3469000000000002 +0.1251000000000002 +0.5248000000000004 +0.01750000000000007 +0.006899999999999906 +0.3336999999999999 +0.1576000000000004 +0.009999999999999787 +0.5124 +0.2801999999999998 +0.6326999999999998 +0.6408 +0.1741999999999999 +0.12650000000000006 +0.6406000000000001 +0.6326999999999998 +0.6318000000000001 +0.5358999999999998 +0.6267 +0.007500000000000284 +0.11819999999999986 +0.4416000000000002 +0.020000000000000018 +0.006899999999999906 +0.20900000000000007 +0.6273000000000004 +0.12509999999999977 +0.06999999999999984 +0.08599999999999985 +0.6061000000000001 +0.08650000000000002 +0.1701999999999999 +0.4537 +0.16779999999999973 +0.1269 +0.3734000000000002 +0.19289999999999985 +0.09209999999999985 +0.41270000000000007 +0.3230999999999997 +0.23360000000000003 +0.017300000000000093 +0.39949999999999974 +0.03300000000000036 +0.5611000000000002 +0.3144 +0.6524000000000001 +0.6877 +0.5758000000000001 +0.030299999999999994 +0.03670000000000018 +0.2610000000000001 +0.5045999999999999 +0.7925999999999997 +0.9799000000000002 +0.5478000000000001 +1.0 +1.1014 +0.5909 +0.7065999999999999 +0.9297 +0.1459999999999999 +0.7947000000000002 +0.9892999999999996 +0.9578000000000002 +0.7828999999999997 +0.8378999999999999 +0.5206999999999997 +0.18930000000000025 +0.7066000000000003 +0.7390000000000003 +0.8055000000000003 +0.41890000000000027 +0.8525999999999998 +0.9274 +0.9176000000000002 +0.7709000000000001 +0.7909000000000002 +1.1284 +0.7791000000000001 +0.7177000000000002 +0.9264999999999999 +0.9618000000000002 +0.8904000000000001 +0.8001999999999998 +0.1943999999999999 +0.7046999999999999 +0.6955999999999998 +0.6705000000000001 +0.7284999999999999 +0.04459999999999997 +0.19169999999999998 +0.3384999999999998 +0.0029000000000003467 +0.6314000000000002 +0.2648999999999999 +0.032200000000000006 +0.4121999999999999 +0.029799999999999827 +0.12139999999999995 +0.1189 +0.8117000000000001 +0.19130000000000003 +0.3525999999999998 +0.3644000000000003 +0.8157000000000001 +0.1835 +0.8099999999999996 +0.41889999999999983 +0.8024 +0.6855000000000002 +0.8098999999999998 +0.7614000000000001 +0.7765999999999997 +0.7581000000000002 +0.7549999999999999 +0.8168000000000002 +0.7859000000000003 +0.6367999999999996 +0.7096 +0.6475 +0.3456999999999999 +0.7633000000000001 +0.6550000000000002 +0.7628000000000004 +0.7568000000000001 +0.6539999999999999 +0.7622 +0.6476999999999999 +0.7263999999999999 +0.8336999999999999 +0.6334 +0.6373000000000002 +0.6263999999999998 +0.7323999999999997 +0.6717999999999997 +0.7955000000000001 +0.6837 +0.7298 +0.7993000000000001 +0.6381999999999999 +0.7231999999999998 +0.7263999999999999 +0.6854 +0.7957000000000001 +0.6656000000000004 +0.4573999999999998 +0.6657000000000002 +0.7368000000000001 +0.5522 +0.5772000000000004 +0.7218 +0.7615000000000003 +0.6941000000000002 +0.7067999999999999 +0.7183999999999999 +0.7877000000000001 +0.7662 +0.7609999999999997 +0.7125999999999997 +0.6595999999999997 +0.6619000000000002 +0.6843000000000004 +0.6237999999999997 +0.49739999999999984 +0.6141999999999999 +0.6342000000000003 +0.5461 +0.6840999999999999 +0.5687000000000002 +0.7079 +0.6547000000000001 +0.6989000000000001 +0.6716000000000002 +0.5226000000000002 +0.7797000000000001 +0.2557999999999998 +0.7169000000000001 +0.2755000000000001 +0.6273 +0.8485 +0.5503 +0.6158000000000001 +0.7445000000000002 +1.1709 +0.9842 +0.6885000000000001 +0.2608999999999997 +0.09689999999999999 +0.2883 +1.004 +0.4274 +0.8125 +0.10799999999999987 +0.5455000000000001 +0.48760000000000003 +0.8788999999999998 +0.6597999999999999 +0.8788 +0.5735000000000001 +1.028 +0.9205999999999999 +0.22740000000000005 +0.5608999999999997 +0.2881999999999998 +0.3023 +0.05230000000000001 +0.1347999999999998 +1.0745 +0.4641000000000002 +0.04410000000000003 +0.11159999999999992 +0.4485000000000001 +0.504 +0.9122000000000001 +1.0266 +0.7598999999999998 +0.029099999999999904 +0.5665999999999998 +0.14210000000000012 +0.1069 +0.058800000000000185 +0.022399999999999753 +0.08150000000000013 +0.0009999999999998899 +0.2947000000000002 +0.03720000000000012 +0.06879999999999997 +0.0777000000000001 +0.26860000000000017 +0.3115000000000001 +0.3622000000000001 +0.43889999999999985 +0.04579999999999984 +0.35040000000000004 +0.020299999999999763 +0.11699999999999999 +0.20929999999999982 +0.09739999999999993 +0.3132999999999999 +0.06160000000000032 +0.1115999999999997 +0.17510000000000003 +0.47119999999999984 +0.34650000000000025 +0.10329999999999995 +0.2931999999999999 +0.3809999999999998 +0.0685 +0.3038000000000003 +0.3426 +0.3268 +0.28289999999999993 +0.020999999999999908 +0.009400000000000075 +0.05900000000000016 +0.11009999999999986 +0.3117000000000001 +0.28090000000000037 +0.2228000000000001 +0.1054999999999997 +0.02660000000000018 +0.11460000000000004 +0.3272999999999997 +0.2015 +0.06040000000000001 +0.3316000000000001 +0.37070000000000003 +0.45440000000000014 +0.09240000000000004 +0.14100000000000024 +0.3971999999999998 +0.4301999999999997 +0.24899999999999967 +0.37239999999999984 +0.44730000000000025 +0.4507000000000003 +0.19530000000000003 +0.0464 +0.05689999999999995 +0.12719999999999976 +0.2248000000000001 +0.05510000000000015 +0.32440000000000024 +0.2379 +0.45950000000000024 +0.9268000000000001 +0.7267999999999999 +0.8954 +0.7079 +0.8369 +0.8905000000000003 +0.7632000000000003 +0.8885000000000001 +0.5550999999999999 +0.7960000000000003 +0.9803999999999999 +0.8166000000000002 +0.8948 +0.6725999999999996 +0.2368999999999999 +0.7614999999999998 +0.5804999999999998 +0.4277000000000002 +0.7864 +0.5997999999999997 +0.8721000000000001 +0.8588999999999998 +0.6341999999999999 +0.8331 +0.8057000000000001 +0.7384 +0.7394000000000003 +0.6154999999999999 +0.2921999999999998 +0.44419999999999993 +0.4264000000000001 +0.1392000000000002 +0.29700000000000015 +0.04059999999999997 +0.030899999999999928 +0.6467999999999998 +0.15149999999999997 +0.4658000000000002 +0.16830000000000034 +0.42179999999999973 +0.16389999999999993 +0.5791 +0.40439999999999987 +0.6598000000000002 +0.05569999999999986 +0.014899999999999913 +0.026499999999999968 +0.39469999999999983 +0.6540000000000004 +0.16860000000000008 +0.7372000000000001 +0.29769999999999985 +0.2502 +0.7768999999999999 +0.7950999999999997 +0.7250999999999999 +0.5051999999999999 +0.46450000000000014 +0.25139999999999985 +0.06769999999999987 +0.8641000000000001 +0.13169999999999993 +0.5737000000000001 +0.3943000000000003 +0.3080000000000003 +0.33820000000000006 +0.42379999999999995 +0.7002000000000002 +0.11840000000000028 +0.3281999999999998 +0.7122000000000002 +0.5155000000000003 +0.8077000000000001 +0.7317999999999998 +0.38390000000000013 +0.4024000000000001 +0.7860999999999998 +0.7272000000000003 +0.7936000000000001 +0.7593000000000001 +0.6778 +0.766 +0.5497999999999998 +0.7597 +0.5658000000000003 +0.6440000000000001 +0.7521 +0.7031999999999998 +0.35029999999999983 +0.4213999999999998 +0.5772000000000004 +0.9401999999999999 +0.7560000000000002 +1.0099 +0.8578999999999999 +0.9133 +0.37040000000000006 +0.7752999999999997 +0.7492000000000001 +0.7968000000000002 +0.7425999999999999 +0.8502000000000001 +0.8101000000000003 +0.6976 +0.8129999999999997 +0.7799999999999998 +0.7652999999999999 +0.7864 +0.5286999999999997 +0.4746999999999999 +0.2913999999999999 +0.6957999999999998 +0.4859 +0.41480000000000006 +0.22990000000000022 +0.8757999999999999 +0.8491 +0.7803999999999998 +0.6992000000000003 +0.714 +0.25760000000000005 +0.7505999999999999 +0.8039000000000001 +1.0317999999999996 +0.8256000000000001 +0.5452999999999997 +0.9470999999999998 +1.0426000000000002 +1.0772 +1.0292999999999997 +0.766 +0.5169000000000001 +0.4299000000000004 +0.7223000000000002 +0.43989999999999974 +0.7154000000000003 +0.7745000000000002 +0.5308000000000002 +0.7405999999999997 +0.7159999999999997 +0.4563999999999999 +0.18500000000000005 +0.5390999999999999 +0.3820000000000001 +0.5566 +0.3092999999999999 +0.8804999999999996 +0.48870000000000013 +0.4235000000000002 +0.8172999999999999 +0.73 +0.8608000000000002 +0.9109000000000003 +0.6147999999999998 +0.6757999999999997 +0.7234000000000003 +0.13859999999999983 +0.6402999999999999 +0.025500000000000078 +0.5874000000000001 +0.9017 +0.6222000000000003 +0.5634999999999999 +0.5375999999999999 +0.05190000000000028 +0.2275999999999998 +0.9495 +0.19099999999999984 +0.7996000000000003 +0.6417999999999999 +0.7783000000000002 +0.09440000000000026 +0.08409999999999984 +0.3419000000000003 +0.35399999999999965 +0.35020000000000007 +0.5158 +0.026100000000000012 +0.3004000000000002 +0.08969999999999967 +0.03189999999999982 +0.7850000000000001 +0.26339999999999986 +0.11519999999999997 +0.025100000000000122 +0.0050000000000001155 +0.5441000000000003 +0.42379999999999995 +0.5484999999999998 +0.42510000000000003 +0.017699999999999827 +0.008299999999999974 +0.013900000000000023 +0.038899999999999935 +0.008700000000000152 +0.021600000000000064 +0.017199999999999882 +0.024799999999999933 +0.17200000000000015 +0.02629999999999999 +0.0030000000000001137 +0.08640000000000025 +0.010499999999999954 +0.01609999999999978 +0.03200000000000003 +0.0028999999999999027 +0.007699999999999818 +0.013400000000000079 +0.18090000000000006 +0.19290000000000007 +0.013700000000000045 +0.0660999999999996 +0.0828000000000002 +0.133 +0.006700000000000372 +0.4253 +0.1640999999999999 +0.32120000000000015 +0.2692999999999999 +0.3496999999999999 +0.0653999999999999 +0.05689999999999995 +0.1057999999999999 +0.09460000000000002 +0.02210000000000001 +0.6585000000000001 +0.06510000000000016 +0.42230000000000034 +0.010199999999999987 +0.5588000000000002 +0.8073999999999999 +0.034499999999999975 +0.09600000000000009 +0.8243 +0.17280000000000006 +0.02220000000000022 +0.6411000000000002 +0.4973000000000001 +0.3727999999999998 +0.5531000000000001 +0.22409999999999997 +0.7937999999999996 +0.022499999999999964 +0.02719999999999967 +0.4599000000000002 +0.18300000000000005 +0.6390000000000002 +0.6288000000000002 +0.31120000000000037 +0.19459999999999988 +0.5410999999999997 +0.48009999999999975 +0.6529000000000003 +0.7445999999999997 +0.5136999999999996 +0.6269999999999998 +0.11319999999999997 +0.24180000000000001 +0.07810000000000006 +0.593 +0.42600000000000016 +0.5139 +0.5150999999999999 +0.4812000000000003 +0.06379999999999986 +0.25829999999999975 +0.8407 +0.7039 +0.17820000000000014 +0.7793000000000001 +0.18839999999999968 +0.5282 +0.7511000000000001 +0.16220000000000034 +0.7852000000000001 +0.5632999999999999 +0.0354000000000001 +0.6274000000000002 +0.44189999999999996 +0.5824 +0.41889999999999983 +0.4554999999999998 +0.637 +0.8008000000000002 +0.6964999999999999 +0.774 +0.07790000000000008 +0.06099999999999994 +0.39359999999999973 +0.18710000000000004 +0.4281999999999999 +0.7077999999999998 +0.7654000000000001 +0.8738999999999999 +0.8515000000000001 +0.5428000000000002 +0.8182 +0.8404000000000003 +0.00890000000000013 +0.2804 +0.02499999999999991 +0.2054999999999998 +0.37429999999999986 +0.5485000000000002 +0.14349999999999996 +0.3647 +0.09649999999999981 +0.005399999999999849 +0.024900000000000144 +0.3849999999999998 +0.09779999999999989 +1.0356999999999998 +0.8504999999999998 +0.266 +0.3719999999999999 +0.8281000000000001 +0.7046000000000001 +0.023299999999999876 +0.7197 +0.8891999999999998 +0.6211000000000002 +0.5764999999999998 +0.4371999999999998 +0.6012999999999997 +0.5605000000000002 +1.2159999999999997 +0.6352000000000002 +0.37860000000000005 +0.45669999999999966 +0.8049 +0.6925999999999997 +0.6562000000000001 +0.22219999999999995 +0.5023999999999997 +0.0026999999999999247 +0.6065 +0.32650000000000023 +0.007800000000000029 +0.15850000000000009 +0.9691000000000005 +0.5028999999999999 +0.8135000000000003 +0.4548000000000001 +0.31659999999999977 +0.13050000000000006 +0.3472999999999997 +0.33630000000000004 +0.5019 +0.46960000000000024 +0.391 +1.0119000000000002 +1.0059999999999998 +0.7039999999999997 +0.29689999999999994 +0.6595999999999997 +0.11900000000000022 +0.6345000000000001 +0.6697000000000002 +0.8494000000000002 +1.0348000000000002 +0.4706999999999999 +0.33630000000000004 +0.9539 +0.7748000000000004 +1.0436 +0.5358999999999998 +0.6574 +0.7839999999999998 +0.6928999999999998 +0.37349999999999994 +0.26370000000000005 +0.6774 +0.7624 +0.5930999999999997 +0.7802000000000002 +0.6183999999999998 +0.5527000000000002 +0.2761 +0.8552 +0.5949 +0.2523000000000004 +0.5301 +0.7542999999999997 +0.49960000000000004 +0.56 +0.5882999999999998 +0.8344 +0.11760000000000037 +0.06489999999999974 +0.5011000000000001 +0.3858999999999999 +0.2591999999999999 +0.02589999999999959 +0.4321999999999999 +0.3171000000000004 +0.031099999999999905 +0.048799999999999955 +0.9106000000000001 +0.4562999999999997 +0.9678 +0.019200000000000106 +0.03929999999999989 +0.020099999999999785 +0.006699999999999928 +0.007800000000000029 +0.3996999999999997 +0.02010000000000023 +0.3144999999999998 +0.0024000000000001798 +0.2025999999999999 +0.21799999999999997 +0.1513 +0.05900000000000016 +0.00509999999999966 +0.1867000000000001 +0.05859999999999976 +0.018199999999999772 +0.006500000000000394 +0.0032999999999998586 +0.017000000000000348 +0.05150000000000032 +0.023699999999999832 +0.5738999999999996 +0.00019999999999997797 +0.00509999999999966 +0.047900000000000276 +0.042200000000000015 +0.6073999999999997 +0.7713000000000001 +0.7910999999999997 +0.7881 +0.8014999999999999 +0.7686000000000002 +0.8275000000000001 +0.15629999999999988 +0.23519999999999985 +0.4802999999999997 +0.3691 +0.1198999999999999 +0.20730000000000004 diff --git a/examples/tadf/TADF_Est/Est.py b/examples/tadf/TADF_Est/Est.py new file mode 100644 index 000000000..f46fcadd6 --- /dev/null +++ b/examples/tadf/TADF_Est/Est.py @@ -0,0 +1,25 @@ +import hydra +from Est_model import eval +from Est_model import featurize_molecules +from Est_model import load_data +from Est_model import train +from omegaconf import DictConfig + + +@hydra.main(version_base=None, config_path="./config", config_name="est.yaml") +def main(cfg: DictConfig): + + data, smis = load_data(cfg) + + X = featurize_molecules(smis) + + if cfg.mode == "train": + train(cfg, X, data) + elif cfg.mode == "eval": + eval(cfg, X, data) + else: + raise ValueError(f"cfg.mode should in ['train', 'eval'], but got '{cfg.mode}'") + + +if __name__ == "__main__": + main() diff --git a/examples/tadf/TADF_Est/Est_model.py b/examples/tadf/TADF_Est/Est_model.py new file mode 100644 index 000000000..547c02a0a --- /dev/null +++ b/examples/tadf/TADF_Est/Est_model.py @@ -0,0 +1,185 @@ +import os + +import matplotlib.pyplot as plt +import numpy as np +import paddle +import rdkit.Chem as Chem +from omegaconf import DictConfig +from rdkit.Chem import rdFingerprintGenerator +from sklearn.decomposition import PCA +from sklearn.metrics import r2_score +from sklearn.model_selection import train_test_split + +import ppsci + +os.environ["HYDRA_FULL_ERROR"] = "1" +os.environ["KMP_DUPLICATE_LIB_OK"] = "True" +plt.rcParams["axes.unicode_minus"] = False +plt.rcParams["font.sans-serif"] = ["DejaVu Sans"] + +# 加载数据集 +def load_data(cfg): + data_dir = cfg.data_dir + sim_dir = cfg.sim_dir + angle_dat_path = os.path.join(data_dir) + smis_txt_path = os.path.join(sim_dir) + + data = [] + with open(angle_dat_path) as f: + for line in f: + num = float(line.strip()) + data.append(num) + + smis = [] + with open(smis_txt_path) as f: + for line in f: + smis.append(line.strip()) + + return data, smis + + +def featurize_molecules(smis): + vectors = [] + del_mol = [] + for s in smis: + mol = Chem.MolFromSmiles(s) + try: + generator = rdFingerprintGenerator.GetMorganGenerator(radius=2, fpSize=2048) + fp = generator.GetFingerprint(mol) + _input = np.array(list(map(int, fp.ToBitString()))) + vectors.append(_input) + except Exception as e: + print(f"Error processing {s}: {e}") + del_mol.append(s) + pca = PCA(n_components=0.99) + pca.fit(vectors) + X = pca.transform(vectors) + return paddle.to_tensor(X, dtype="float32") + + +def train(cfg: DictConfig, X, data): + # 划分数据集 + def k_fold(k, i, X, Y): + fold_size = tuple(X.shape)[0] // k + val_start = i * fold_size + if i != k - 1: + val_end = (i + 1) * fold_size + x_val, y_val = X[val_start:val_end], Y[val_start:val_end] + x_train = np.concatenate((X[0:val_start], X[val_end:]), axis=0) + y_train = np.concatenate((Y[0:val_start], Y[val_end:]), axis=0) + else: + x_val, y_val = X[val_start:], Y[val_start:] + x_train = X[0:val_start] + y_train = Y[0:val_start] + return x_train, y_train, x_val, y_val + + Y = paddle.to_tensor(data, dtype="float32") + x_train, y_train, x_test, y_test = k_fold(cfg.TRAIN.k, cfg.TRAIN.i, X, Y) + # 处理数据集 + x_train = paddle.to_tensor(x_train, dtype="float32") + x = { + "key_{}".format(i): paddle.unsqueeze( + paddle.to_tensor(x_train[:, i], dtype="float32"), axis=1 + ) + for i in range(x_train.shape[1]) + } + y_train = paddle.unsqueeze(paddle.to_tensor(y_train, dtype="float32"), axis=1) + + # 构建约束 + bc_sup = ppsci.constraint.SupervisedConstraint( + dataloader_cfg={ + "dataset": { + "input": x, + "label": {"u": y_train}, + "name": "IterableNamedArrayDataset", + }, + "batch_size": cfg.TRAIN.batch_size, + }, + loss=ppsci.loss.MSELoss("mean"), + name="bc_sup", + ) + + # 设置模型 + hidden_size = [587, 256] + num_layers = None + + # 实例化模型 + model = ppsci.arch.TADF( + input_keys=tuple(x.keys()), + hidden_size=hidden_size, + num_layers=num_layers, + **cfg.MODEL, + ) + optimizer = ppsci.optimizer.optimizer.Adam( + cfg.TRAIN.learning_rate, + beta1=(0.9, 0.99)[0], + beta2=(0.9, 0.99)[1], + weight_decay=cfg.TRAIN.weight_decay, + )(model) + # 构建Solver + solver = ppsci.solver.Solver( + model, + constraint={ + "bc_sup": bc_sup, + }, + optimizer=optimizer, + epochs=cfg.TRAIN.epochs, + eval_during_train=False, + iters_per_epoch=cfg.TRAIN.iters_per_epoch, + seed=cfg.seed, + ) + try: + solver.train() + except Exception as ex: + print("error", ex) + paddle.save(model.state_dict(), cfg.TRAIN.save_model_path) + + +# 进行测试 +def eval(cfg: DictConfig, X, data): + y = paddle.to_tensor(data) + # 重新划分数据集 + x_train, x_test, y_train, y_test = train_test_split( + X.numpy(), y.numpy(), test_size=cfg.EVAL.test_size, random_state=cfg.EVAL.seed + ) + x = { + "key_{}".format(i): paddle.unsqueeze( + paddle.to_tensor(x_test[:, i], "float32"), axis=1 + ) + for i in range(x_test.shape[1]) + } + hidden_size = [587, 256] + num_layers = None + model = ppsci.arch.TADF( + input_keys=tuple(x.keys()), + hidden_size=hidden_size, + num_layers=num_layers, + **cfg.MODEL, + ) + model.set_state_dict(paddle.load(cfg.EVAL.load_model_path)) + ytest = paddle.unsqueeze(paddle.to_tensor(y_test, dtype="float32"), axis=1) + ypred = model(x) + ytest = {"u": ytest} + + # 计算损失 + loss = ppsci.metric.MAE() + MAE = loss(ypred, ytest).get("u").numpy() + loss = ppsci.metric.RMSE() + RMSE = loss(ypred, ytest).get("u").numpy() + ypred = ypred.get("u").numpy() + ytest = ytest.get("u").numpy() + R2 = r2_score(ytest, ypred) + print("MAE", MAE) + print("RMSE", RMSE) + print("R2", R2) + + # 可视化 + plt.scatter(ytest, ypred, s=15, color="royalblue", marker="s", linewidth=1) + plt.plot([ytest.min(), ytest.max()], [ytest.min(), ytest.max()], "r-", lw=1) + plt.legend(title=f"R²={R2:.3f}\n\nMAE={MAE:.3f}") + plt.xlabel("Test ΔEst(eV)") + plt.ylabel("Predicted ΔEst(eV)") + save_path = "test_Est.png" + plt.savefig(save_path) + print(f"图片已保存至：{save_path}") + plt.show() diff --git a/examples/tadf/TADF_Est/config/est.yaml b/examples/tadf/TADF_Est/config/est.yaml new file mode 100644 index 000000000..65d1fc1f0 --- /dev/null +++ b/examples/tadf/TADF_Est/config/est.yaml @@ -0,0 +1,84 @@ +defaults: # + - ppsci_default # + - TRAIN: train_default # + - EVAL: eval_default # +# - INFER: infer_default # + - _self_ # + +hydra: + run: + # dynamic output directory according to running time and override name + dir: outputs_Est/${now:%Y-%m-%d}/${now:%H-%M-%S}/${hydra.job.override_dirname} # + job: + name: ${mode} # name of logfile + chdir: false # keep current working directory unchanged + callbacks: + init_callback: # + _target_: ppsci.utils.callbacks.InitCallback # + sweep: + # output directory for multirun + dir: ${hydra.run.dir} + subdir: ./ + +# general settings +mode: eval # running mode: train/eval # +seed: 42 # +output_dir: ${hydra:run.dir} # +log_freq: 20 # +use_tbd: false # +VIV_DATA_PATH: "./Est.dat" # +data_dir: "./Est.dat" +sim_dir: "./smis.txt" + +# model settings +MODEL: # +# input_keys: tuple(x.keys()) # + output_keys: ["u"] # +# num_layers: None # +# hidden_size: +# - 587 +# - 256 # + activation: "relu" # + dropout: 0.5 + +# training settings +TRAIN: # + epochs: 200 # + iters_per_epoch: 20 # + save_freq: 100 # + eval_during_train: False # + batch_size: 8 # + learning_rate: 0.0001 + save_model_path: './est_model.pth' + weight_decay: 1e-5 + pretrained_model_path: null # + checkpoint_path: null # + k: 9 + i: 2 + +# evaluation settings +EVAL: + test_size: 0.1 + load_model_path: './Est_pretrained.pdparams' + seed: 20 +# pretrained_model_path: null # +# batch_size: 32 # + +# inference settings +#INFER: # +# pretrained_model_path: "https://github.com/YfB1125/PaddleScience/blob/dev_model/TADF/f/output/checkpoints/latest.pdparams" # +# export_path: ./inference/viv # +# pdmodel_path: ${INFER.export_path}.pdmodel # +# pdiparams_path: ${INFER.export_path}.pdiparams # +# input_keys: ${MODEL.input_keys} # +# output_keys: ["u"] # +# device: cpu # +# engine: native # +# precision: fp32 # +# ir_optim: true # +# min_subgraph_size: 10 # +# gpu_mem: 4000 # +# gpu_id: 0 # +# max_batch_size: 64 # +# num_cpu_threads: 4 # +# batch_size: 16 # diff --git a/examples/tadf/TADF_Est/smis.txt b/examples/tadf/TADF_Est/smis.txt new file mode 100644 index 000000000..06fd4771c --- /dev/null +++ b/examples/tadf/TADF_Est/smis.txt @@ -0,0 +1,5136 @@ +c1cc(-c2c3ccoc3cc3ccoc23)n[nH]1 +c1cc(-c2c3cc[nH]c3cc3occc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c3cc[nH]c3cc3occc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2c3cc[nH]c3cc3occc23)c2[nH]nnc2c1 +c1cc(-c2c3ncoc3cc3ncoc23)c2c(c1)cnc1ccccc12 +c1cc(-c2c3ncoc3nc3ocnc23)c2nn[nH]c2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2scnc2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2[nH]c3ccncc3c2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2[nH]ccc2c1 +c1cc(-c2c3ncoc3nc3ocnc23)cnn1 +c1cc(-c2c3ncsc3cc3ncsc23)c2ncoc2c1 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2c(c1)sc1ncccc12 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2ccoc2c1 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2c(c1)cnc1ccccc12 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2ocnc2c1 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2[nH]nnc2c1 +c1cc(-c2c3[nH]cnc3cc3nc[nH]c23)c2[nH]nnc2c1 +c1cc(-c2c3[nH]cnc3cc3nc[nH]c23)[nH]n1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cc3cccnc3c3ncccc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cc3[nH]ccc3cn2)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccc3c(c2)[nH]c2cnccc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cccc3cnc4ccccc4c23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cccc3ocnc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccnc3c2ccc2cccnc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cncc3[nH]c4ccccc4c23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2coc3cc4ccoc4cc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2nc3cc4ncoc4nc3o2)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-n2cnc3cc4nc[nH]c4cc32)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)ccc1-c1cnoc1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2nccnc2c1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2sccc2c1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2[nH]c3cnccc3c2c1 +c1cc(-c2cc3cc4cc[nH]c4cc3o2)c2ocnc2c1 +c1cc(-c2cc3cc4cc[nH]c4cc3o2)c2[nH]nnc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2ncsc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2occc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2ocnc2c1 +c1cc(-c2cc3cnccc3[nH]2)c2nn[nH]c2c1 +c1cc(-c2cc3cnccc3[nH]2)c2occc2c1 +c1cc(-c2cc3cnccc3[nH]2)c2[nH]c3ccncc3c2c1 +c1cc(-c2cc3cnccc3[nH]2)c2[nH]nnc2c1 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2[nH]c3ccncc3c2c1 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2[nH]ccc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2ccoc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2ccsc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2cc[nH]c2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)n[nH]1 +c1cc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c2nccnc2c1 +c1cc(-c2cc3[nH]c4ccccc4c3cn2)c2nccnc2c1 +c1cc(-c2cc3[nH]c4ccccc4c3cn2)c2sccc2c1 +c1cc(-c2cc3[nH]c4ccncc4c3cn2)c2ccoc2c1 +c1cc(-c2cc3[nH]ccc3cn2)c2c(c1)sc1ncccc12 +c1cc(-c2cc3[nH]ccc3cn2)c2ncoc2c1 +c1cc(-c2cc3[nH]ccc3cn2)c2nn[nH]c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2cc[nH]c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2ncsc2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2[nH]nnc2c1 +c1(c2nccnc2)cccc(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +c1cc(-c2ccc3c(c2)c2ccccc2c2nccnc32)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2[nH]nnc2c1 +c1cc(-c2ccc3c(c2)ncc2ccccc23)c2occc2c1 +c1cc(-c2ccc3c(c2)oc2ccccc23)c2nn[nH]c2c1 +c1cc(-c2ccc3c(c2)oc2ncccc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c(c2)sc2ccccc23)c2ccoc2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2nn[nH]c2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2[nH]nnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)cc(-c2cnccn2)c1 +c1cc(-c2ccc3c(c2)[nH]c2ccncc23)c2ocnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ccsc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2cc[nH]c2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ncoc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ocnc2c1 +c1cc(-c2ccc3c(cnc4ccccc43)c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(cnc4ccccc43)c2)c2occc2c1 +c1cc(-c2ccc3c(n2)sc2ncccc23)c2nccnc2c1 +c1cc(-c2ccc3c(n2)sc2ncccc23)c2[nH]nnc2c1 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2cc[nH]c2c1 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2sccc2c1 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2nccnc2c1 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2[nH]nnc2c1 +c1cc(-c2ccc3c4ccccc4c4nccnc4c3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c4ccccc4c4nccnc4c3c2)c2ccsc2c1 +c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)c2sccc2c1 +c1cc(-c2ccc3ccc4cccnc4c3n2)c2[nH]ccc2c1 +c1cc(-c2ccc3ccoc3c2)no1 +c1cc(-c2ccc3ccsc3c2)c2ccoc2c1 +c1cc(-c2ccc3cc[nH]c3c2)c2ncoc2c1 +c1cc(-c2ccc3cc[nH]c3c2)c2nn[nH]c2c1 +c1cc(-c2ccc3cnc4ccccc4c3c2)c2scnc2c1 +c1cc(-c2ccc3cnc4ccccc4c3c2)c2[nH]ccc2c1 +c1cc(-c2ccc3ncc4ccccc4c3c2)c2occc2c1 +c1cc(-c2ccc3ncccc3n2)c2[nH]ccc2c1 +c1cc(-c2ccc3nccnc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3nccnc3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3ncoc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3ncoc3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3ncoc3c2)c2ccoc2c1 +c1cc(-c2ccc3ncoc3c2)c2cc[nH]c2c1 +c1cc(-c2ccc3ncsc3c2)c2sccc2c1 +c1cc(-c2ccc3nn[nH]c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3nn[nH]c3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3oc4ccccc4c3c2)c2nn[nH]c2c1 +c1cc(-c2ccc3oc4ncccc4c3c2)c2ncoc2c1 +c1cc(-c2ccc3oc4ncccc4c3c2)c2ocnc2c1 +c1cc(-c2ccc3occc3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3ocnc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3ocnc3c2)c2ncsc2c1 +c1cc(-c2ccc3ocnc3c2)c2occc2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3sc4ccccc4c3c2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3sc4ccccc4c3c2)c2cc[nH]c2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2ncoc2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2[nH]nnc2c1 +c1cc(-c2ccc3sccc3c2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3sccc3c2)c2ncoc2c1 +c1cc(-c2ccc3sccc3c2)c2sccc2c1 +c1cc(-c2ccc3sccc3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3sccc3c2)c2[nH]ccc2c1 +c1cc(-c2ccc3sccc3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3scnc3c2)c2ocnc2c1 +c1cc(-c2ccc3scnc3c2)no1 +c1cc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3[nH]c4ccncc4c3c2)c2[nH]nnc2c1 +c1cc(-c2ccc3[nH]c4cnccc4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ccoc2c1 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ncsc2c1 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ocnc2c1 +c1cc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]nnc3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3[nH]nnc3c2)c2ncoc2c1 +c1cc(-c2ccc3[nH]nnc3c2)c2scnc2c1 +c1cc(-c2cccc3c2cnc2ccccc23)c2ocnc2c1 +c1cc(-c2cccc3c2oc2ccccc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3c2oc2ccccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3c2sc2ncccc23)c2nn[nH]c2c1 +c1cc(-c2cccc3c2sc2ncccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c2nccnc2c1 +c1cc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c2ocnc2c1 +c1cc(-c2cccc3c2[nH]c2ccncc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3c2[nH]c2ccncc23)c2ocnc2c1 +c1cc(-c2cccc3c2[nH]c2cnccc23)c2scnc2c1 +c1cc(-c2cccc3c2[nH]c2cnccc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)c2nccnc2c1 +c1cc(-c2cccc3c4ccccc4c4nccnc4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c2nccnc2c1 +c1cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c2ncoc2c1 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2ccsc2c1 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2nn[nH]c2c1 +c1cc(-c2cccc3ccsc23)c2[nH]ccc2c1 +c1cc(-c2cccc3ncoc23)c2nccnc2c1 +c1cc(-c2cccc3ncsc23)c2nccnc2c1 +c1cc(-c2cccc3nn[nH]c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2sccc2c1 +c1cc(-c2cccc3oc4ncccc4c23)c2nccnc2c1 +c1cc(-c2cccc3oc4ncccc4c23)c2sccc2c1 +c1cc(-c2cccc3ocnc23)c2ccoc2c1 +c1cc(-c2cccc3ocnc23)c2occc2c1 +c1cc(-c2cccc3sc4ncccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3sc4ncccc4c23)c2ocnc2c1 +c1cc(-c2cccc3sccc23)c2ccsc2c1 +c1cc(-c2cccc3scnc23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3scnc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3[nH]c4cnccc4c23)c2occc2c1 +c1cc(-c2cccc3[nH]c4ncccc4c23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c2nccnc2c1 +c1cc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c2nn[nH]c2c1 +c1cc(-c2cccc3[nH]ccc23)c2ocnc2c1 +c1cc(-c2cccc3[nH]ccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3[nH]nnc23)c2occc2c1 +c1cc(-c2ccnc3c2ccc2cccnc23)c2[nH]ccc2c1 +c1cc(-c2ccnc3cccnc23)c2[nH]ccc2c1 +c1cc(-c2ccnc3ncccc23)c2scnc2c1 +c1cc(-c2ccnc3oc4ccccc4c23)c2sccc2c1 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2ncoc2c1 +c1cc(-c2ccnc3[nH]c4ccccc4c23)c2[nH]ccc2c1 +c1cc(-c2ccnnc2)c2sccc2c1 +c1cc(-c2ccno2)c2c(c1)oc1ncccc12 +c1cc(-c2ccno2)c2c(c1)sc1ncccc12 +c1cc(-c2ccno2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ccno2)[nH]n1 +c1cc(-c2ccn[nH]2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccon2)c2ccoc2c1 +c1cc(-c2ccon2)c2nn[nH]c2c1 +c1cc(-c2ccon2)n[nH]1 +c1cc(-c2cc[nH]n2)c2ccsc2c1 +c1cc(-c2cc[nH]n2)c2ncoc2c1 +c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c2ocnc2c1 +c1cc(-c2cnc3ccccc3n2)c2c(c1)cnc1ccccc12 +c1cc(-c2cnc3nccnc3n2)c2ccoc2c1 +c1cc(-c2cnc3nccnc3n2)c2ncoc2c1 +c1cc(-c2cnc3nccnc3n2)c2[nH]c3cnccc3c2c1 +c1cc(-c2cnc3oc4ccccc4c3c2)c2sccc2c1 +c1cc(-c2cnc3oc4ccccc4c3c2)c2[nH]nnc2c1 +c1cc(-c2cnc3sc4ccccc4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2cnc3sc4ncccc4c3c2)c2nn[nH]c2c1 +c1cc(-c2cnc3sc4ncccc4c3c2)cc(-c2cnccn2)c1 +c1cc(-c2cncc3c2[nH]c2ccncc23)c2c(c1)sc1ncccc12 +c1cc(-c2cncc3cc[nH]c23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cncc3cc[nH]c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cncc3cc[nH]c23)c2ncsc2c1 +c1cc(-c2cncc3cc[nH]c23)c2[nH]c3ccncc3c2c1 +c1cc(-c2cncc3cc[nH]c23)c2[nH]nnc2c1 +c1cc(-c2cncc3[nH]c4ccccc4c23)c2[nH]ccc2c1 +c1cc(-c2cnccn2)cc(-c2cc3ccccc3s2)c1 +c1cc(-c2cnccn2)cc(-c2cc3ccccc3[nH]2)c1 +c1cc(-c2cnccn2)cc(-c2cc3nc4ccoc4nc3[nH]2)c1 +c1cc(-c2cnccn2)cc(-c2cccc3ncc4ccccc4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3oc4ncccc4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3sccc23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3[nH]ccc23)c1 +c1cc(-c2cnccn2)cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +c1cc(-c2cnccn2)cc(-c2coc3cc4ccoc4cc23)c1 +c1cc(-c2cnccn2)cc(-c2c[nH]c3nc4occc4nc23)c1 +c1cc(-c2cnccn2)cc(-c2nccc3[nH]c4ccncc4c23)c1 +c1cc(-c2cnccn2)cc(-n2c3ccccc3c3c4ccccc4[nH]c32)c1 +c1cc(-c2cnccn2)cc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c1 +c1cc(-c2cnccn2)cc(-n2ccc3cc4ccoc4cc32)c1 +c1cc(-c2cnccn2)cc(-n2cnc3c4ccccc4c4ccccc4c32)c1 +c1cc(-c2cncs2)c2[nH]ccc2c1 +c1cc(-c2cnoc2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cnoc2)c2ccoc2c1 +c1cc(-c2cnoc2)[nH]n1 +c1cc(-c2cn[nH]c2)c2c(c1)cnc1ccccc12 +c1cc(-c2cn[nH]c2)c2[nH]nnc2c1 +c1cc(-c2cn[nH]c2)on1 +c1cc(-c2coc3cc4ccoc4cc23)c2c(c1)cnc1ccccc12 +c1cc(-c2coc3cc4ccoc4cc23)no1 +c1cc(-c2coc3cc4[nH]ccc4cc23)c2ocnc2c1 +c1cc(-c2coc3cc4[nH]ccc4cc23)c2[nH]nnc2c1 +c1cc(-c2coc3ccccc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2coc3ccccc23)c2sccc2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2cc[nH]c2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2ncsc2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2scnc2c1 +c1cc(-c2csc3ccccc23)c2ncoc2c1 +c1cc(-c2c[nH]c3cc4occc4cc23)c2ocnc2c1 +c1cc(-c2c[nH]c3cc4occc4cc23)no1 +c1cc(-c2c[nH]c3ccccc23)c2sccc2c1 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)oc1ncccc12 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c[nH]c3ccncc23)c2ocnc2c1 +c1cc(-c2c[nH]c3ccncc23)c2[nH]c3ccncc3c2c1 +c1cc(-c2c[nH]c3nc4occc4nc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c[nH]c3nc4occc4nc23)n[nH]1 +c1cc(-c2c[nH]c3nc4occc4nc23)[nH]n1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2nc3cc4ncoc4nc3o2)c2cc[nH]c2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2ncsc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2occc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2[nH]c3cnccc3c2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2[nH]ccc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)n[nH]1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)c2occc2c1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)c2sccc2c1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)cnn1 +c1cc(-c2nc3cc4ocnc4cc3o2)c2c(c1)cnc1ccccc12 +c1cc(-c2nc3cc4ocnc4cc3o2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2nc3cc4ocnc4cc3o2)c2ccsc2c1 +c1cc(-c2nc3cc4ocnc4cc3o2)c2[nH]nnc2c1 +c1cc(-c2nc3cc4scnc4cc3s2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2nc3cc4scnc4cc3s2)c2ccsc2c1 +c1cc(-c2nc3cc4scnc4cc3s2)c2nccnc2c1 +c1cc(-c2nc3ccccc3c3ccccc23)c2ocnc2c1 +c1cc(-c2nc3ccccc3o2)c2occc2c1 +c1cc(-c2nc3nc4nc[nH]c4cc3[nH]2)c2c(c1)oc1ncccc12 +c1cc(-c2nc3nc4nc[nH]c4cc3[nH]2)c2cc[nH]c2c1 +c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2c(c1)sc1ncccc12 +c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2[nH]c3cnccc3c2c1 +c1cc(-c2nc3nc4ocnc4nc3o2)c2c(c1)sc1ncccc12 +c1cc(-c2nc3nc4ocnc4nc3o2)c2scnc2c1 +c1cc(-c2nccc3c2[nH]c2ccccc23)c2cc[nH]c2c1 +c1cc(-c2nccc3[nH]c4ccccc4c23)c2[nH]nnc2c1 +c1cc(-c2nccc3[nH]c4ccncc4c23)c2[nH]c3ccncc3c2c1 +c1cc(-c2nccc3[nH]ccc23)c2c(c1)cnc1ccccc12 +c1cc(-c2nccc3[nH]ccc23)c2c(c1)sc1ncccc12 +c1cc(-c2nccc3[nH]ccc23)c2nn[nH]c2c1 +c1cc(-c2nccs2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2nccs2)c2ncsc2c1 +c1cc(-c2nccs2)c2[nH]nnc2c1 +c1cc(-c2ncno2)c2ccoc2c1 +c1cc(-c2ncon2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ncon2)c2sccc2c1 +c1cc(-c2ncon2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ncon2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ncon2)c2[nH]nnc2c1 +c1cc(-c2ncon2)[nH]n1 +c1cc(-n2c3ccccc3c3c4ccccc4[nH]c32)c2[nH]nnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2nccnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2ocnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2sccc2c1 +c1cc(-n2c3ccccc3c3cccnc32)c2c(c1)cnc1ccccc12 +c1cc(-n2c3ccccc3c3cccnc32)c2ncsc2c1 +c1cc(-n2c3ccccc3c3cccnc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2occc2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2[nH]nnc2c1 +c1cc(-n2c3ccccc3c3cnccc32)c2ocnc2c1 +c1cc(-n2c3ccncc3c3cnccc32)c2nn[nH]c2c1 +c1cc(-n2c3ccncc3c3cnccc32)c2ocnc2c1 +c1cc(-n2ccc3cc4ccoc4cc32)c2c(c1)cnc1ccccc12 +c1cc(-n2ccc3cc4ccoc4cc32)c2[nH]c3cnccc3c2c1 +c1cc(-n2ccc3cnccc32)c2c(c1)oc1ncccc12 +c1cc(-n2ccc3cnccc32)c2c(c1)[nH]c1ccncc12 +c1cc(-n2ccc3nc4ccoc4nc32)c2ncoc2c1 +c1cc(-n2cccn2)c2ncoc2c1 +c1cc(-n2cccn2)c2[nH]c3cnccc3c2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)c2ncsc2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)[nH]n1 +c1cc(-n2cnc3nc4nc[nH]c4nc32)c2ncoc2c1 +c1cc(-n2cnc3nc4nc[nH]c4nc32)c2[nH]ccc2c1 +c1cc2c(-c3c4ncoc4nc4ocnc34)c3ccoc3cc2[nH]1 +c1cc2c(-c3ccc4ncoc4c3)c3ccoc3cc2[nH]1 +c1cc2c(-c3ccc4[nH]nnc4c3)c3ccoc3cc2[nH]1 +c1cc2c(-n3cnc4nc5nc[nH]c5nc43)c3ccoc3cc2[nH]1 +c1cc2c(ccn2-c2cc3nc4ccoc4nc3[nH]2)cn1 +c1cc2c(ccn2-c2ccc3c(c2)[nH]c2ccncc23)cn1 +c1cc2c(ccn2-c2c[nH]c3nc4occc4nc23)cn1 +c1cc2c(ccn2-c2nc3cc4ocnc4cc3o2)cn1 +c1cc2c(ccn2-n2c3ccncc3c3cnccc32)cn1 +c1cc2c(ccn2-n2ccc3nc4ccoc4nc32)cn1 +c1cc2c(cn1)c1cnccc1n2-c1c2ccoc2cc2ccoc12 +c1cc2c(cn1)c1cnccc1n2-c1c2ncoc2cc2ncoc12 +c1cc2c(cn1)c1cnccc1n2-c1c2ncoc2nc2ocnc12 +c1cc2c(cn1)c1cnccc1n2-c1c2[nH]cnc2cc2nc[nH]c12 +c1cc2c(cn1)c1cnccc1n2-c1cc2cc3occc3cc2o1 +c1cc2c(cn1)c1cnccc1n2-c1cc2[nH]ccc2cn1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2c3c1CCCN3CCC2 +c1cc2c(cn1)c1cnccc1n2-c1ccc2cc[nH]c2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2ncoc2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2ocnc2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2scnc2c1 +c1cc2c(cn1)c1cnccc1n2-c1c[nH]c2cc3occc3cc12 +c1cc2c(cn1)c1cnccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1cc2c(cn1)[nH]c1cc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4ncoc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4nn[nH]c4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4ocnc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4scnc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1cc2c(cn1)[nH]c1cc(-n3cnc4cc5nc[nH]c5cc43)ccc12 +c1cc2c(cn1)[nH]c1cc(-n3cnc4nc5nc[nH]c5cc43)ccc12 +c1cc2c(cn1)[nH]c1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3ccc4cc[nH]c4c3)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3ccc4[nH]ccc4c3)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3cncc4c3[nH]c3ccncc34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3coc4cc5[nH]ccc5cc34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3nc4cc5ocnc5cc4o3)cc12 +c1cc2cc(-c3ccc4nn[nH]c4c3)ccc2s1 +c1cc2cc(-c3ccc4ocnc4c3)ccc2o1 +c1cc2cc(-n3ccc4nc5ccoc5nc43)ccc2o1 +c1cc2cc3c(-c4c5ncoc5nc5ocnc45)coc3cc2[nH]1 +c1cc2cc3c(-c4ccc5ccsc5c4)c[nH]c3cc2o1 +c1cc2cc3c(-c4ccc5nn[nH]c5c4)c[nH]c3cc2o1 +c1cc2cc3c(-c4ccon4)coc3cc2[nH]1 +c1cc2cc3c(-c4cnoc4)c[nH]c3cc2o1 +c1cc2cc3c(-c4nc5nc6nc[nH]c6nc5[nH]4)coc3cc2[nH]1 +c1cc2cc3c(-c4ncon4)coc3cc2[nH]1 +c1cc2cc3c(-n4cnc5cc6nc[nH]c6cc54)coc3cc2[nH]1 +c1cc2cc3c(-n4cnc5nc6nc[nH]c6cc54)coc3cc2[nH]1 +c1cc2cc3cc(-c4cc5cc6occc6cc5o4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5ccsc5c4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5sccc5c4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5[nH]nnc5c4)[nH]c3cc2o1 +c1cc2cc3cc(-c4coc5cc6ccoc6cc45)[nH]c3cc2o1 +c1cc2cc3cc(-c4nc5cc6ncoc6nc5o4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ncon4)oc3cc2[nH]1 +c1cc2cc3cc(-n4ccc5nc6ccoc6nc54)oc3cc2[nH]1 +c1cc2cc3ccn(-c4ccc5ccsc5c4)c3cc2o1 +c1cc2cc3ccn(-c4ccc5nn[nH]c5c4)c3cc2o1 +c1cc2cc3ccoc3c(-c3c4ncoc4nc4ocnc34)c2[nH]1 +c1cc2cc3ccoc3c(-c3cc4cc5occc5cc4o3)c2[nH]1 +c1cc2cc3ccoc3c(-c3ccc4ccsc4c3)c2[nH]1 +c1cc2cc3occ(-c4cn[nH]c4)c3cc2o1 +c1cc2cc3occ(-n4ccc5nc6ccoc6nc54)c3cc2o1 +c1cc2ccc(-c3ccc4[nH]nnc4c3)cc2[nH]1 +c1cc2ccc(-c3cncs3)cc2[nH]1 +c1cc2ccc(-c3cn[nH]c3)cc2s1 +c1cc2ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc2[nH]1 +c1cc2ccc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc2[nH]1 +c1cc2cnc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)cc2[nH]1 +c1cc2cnc(-c3ccc4scnc4c3)cc2[nH]1 +c1cc2cnc(-c3coc4cc5[nH]ccc5cc34)cc2[nH]1 +c1cc2cnc(-c3c[nH]c4cc5occc5cc34)cc2[nH]1 +c1cc2cnc(-n3ccc4nc5ccoc5nc43)cc2[nH]1 +c1cc2cncc(-c3c4[nH]ccc4cc4ccoc34)c2[nH]1 +c1cc2cncc(-c3ccc4ccsc4c3)c2[nH]1 +c1cc2cncc(-c3ccc4ncoc4c3)c2[nH]1 +c1cc2cncc(-c3ccc4[nH]nnc4c3)c2[nH]1 +c1cc2nc3c(-c4c5ncoc5nc5ocnc45)coc3nc2[nH]1 +c1cc2nc3c(-c4c5ncsc5cc5ncsc45)c[nH]c3nc2o1 +c1cc2nc3c(-c4ccc5nn[nH]c5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4ccc5sccc5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4ccc5[nH]nnc5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4coc5cc6ccoc6cc45)coc3nc2[nH]1 +c1cc2nc3c(-c4nc5nc6ocnc6nc5o4)c[nH]c3nc2o1 +c1cc2nc3cc(-c4c5ncoc5nc5ocnc45)oc3nc2[nH]1 +c1cc2nc3cc(-c4c5ncoc5nc5ocnc45)[nH]c3nc2o1 +c1cc2nc3cc(-c4ccc5ocnc5c4)oc3nc2[nH]1 +c1cc2nc3cc(-c4ccon4)oc3nc2[nH]1 +c1cc2nc3cc(-c4cn[nH]c4)oc3nc2[nH]1 +c1cc2nc3ccn(-c4c5ncsc5cc5ncsc45)c3nc2o1 +c1cc2nc3ccn(-c4ccc5sccc5c4)c3nc2o1 +c1cc2nc3ccn(-c4ccc5scnc5c4)c3nc2o1 +c1cc2nc3ccn(-c4ccc5[nH]nnc5c4)c3nc2o1 +c1cc2nc3ccn(-c4cscn4)c3nc2o1 +c1cc2[nH]c(-c3ccc4sccc4c3)cc2cn1 +c1cc2[nH]c(-c3coc4cc5ccoc5cc34)cc2cn1 +c1cc2[nH]c3c(-c4c5ccoc5cc5ccoc45)cncc3c2cn1 +c1cc2[nH]c3c(-c4c5ncsc5cc5ncsc45)cncc3c2cn1 +c1cc2[nH]c3c(-c4c5[nH]cnc5cc5nc[nH]c45)cncc3c2cn1 +c1cc2[nH]c3c(-c4cc5cc6ccoc6cc5[nH]4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccc5sccc5c4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccc5scnc5c4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccno4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccon4)cncc3c2cn1 +c1cc2[nH]c3c(-c4cnoc4)cncc3c2cn1 +c1cc2[nH]c3c(-c4c[nH]c5nc6occc6nc45)cncc3c2cn1 +c1cc2[nH]c3cc(-c4c5cc[nH]c5cc5occc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cc5c6c(c4)CCCN6CCC5)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cc5cc6ccoc6cc5[nH]4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5ccoc5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5[nH]c6ccncc6c5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5[nH]nnc5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cncc5c4[nH]c4ccncc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4coc5nc6[nH]ccc6nc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4nc5cc6nc[nH]c6cc5[nH]4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4nc5nc6nc[nH]c6cc5[nH]4)ccc3c2cn1 +c1cc2[nH]c3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c2cn1 +c1cc2[nH]c3ccc(-c4cc5nc6cc[nH]c6nc5o4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4cc5[nH]ccc5cn4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4nc5nc6nc[nH]c6nc5[nH]4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4ncon4)cc3c2cn1 +c1cc2[nH]c3ccnc(-c4c5ccoc5cc5ccoc45)c3c2cn1 +c1cc2[nH]c3ccnc(-c4cc5c6c(c4)CCCN6CCC5)c3c2cn1 +c1cc2[nH]c3ccnc(-c4ccc5nn[nH]c5c4)c3c2cn1 +c1cc2[nH]c3ccnc(-c4cnoc4)c3c2cn1 +c1cc2[nH]c3ccnc(-c4ncno4)c3c2cn1 +c1cc2[nH]cc(-c3ccc4[nH]nnc4c3)c2cn1 +c1cc2[nH]cc(-c3ccn[nH]3)c2cn1 +c1cc2[nH]cc(-c3cncc4c3[nH]c3ccncc34)c2cn1 +c1cc2[nH]cc(-c3coc4cc5[nH]ccc5cc34)c2cn1 +c1cc2[nH]cc(-c3coc4nc5[nH]ccc5nc34)c2cn1 +c1cc2[nH]cc(-c3nc4cc5ocnc5cc4o3)c2cn1 +c1cc2[nH]cc(-n3cnc4nc5nc[nH]c5nc43)c2cn1 +c1cc2[nH]ccc2c(-c2cc3cc4ccoc4cc3[nH]2)n1 +c1cc2[nH]ccc2c(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cc2)n1 +c1cc2[nH]ccc2c(-c2ccc3ccoc3c2)n1 +c1ccc(-c2c3[nH]ccc3cc3ccoc23)c(-c2cnccn2)c1 +c1ccc(-c2c3[nH]cnc3cc3nc[nH]c23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1(c2nccc(c2)c2ccc3CCc4c(cccc4)Nc3c2)ncccc1 +c1ccc(-c2cc(-c3ccc4c(n3)sc3ncccc34)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4c5c3CCCN5CCC4)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4oc5ccccc5c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c3sc3ncccc34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c3[nH]c3cnccc34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c5ccccc5c5nccnc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4cnc5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3cncc4[nH]c5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3coc4cc5ccoc5cc34)ccn2)nc1 +c1ccc(-c2cc(-c3coc4nc5[nH]ccc5nc34)ccn2)nc1 +c1ccc(-c2cc(-c3nccc4[nH]c5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc3c4c(c2-c2cc5cccnc5c5ncccc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cc5cnccc5[nH]2)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5c2[nH]c2ncccc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5cnc6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5ocnc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5sc6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cncc5[nH]c6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)c(-c2cnccn2)c1 +c1ccc(-c2cc3nc4cc[nH]c4nc3o2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cc3nc4cc[nH]c4nc3o2)c(-c2cnccn2)c1 +c1(c2ncc(cc2)N2c3c(Sc4c2cccc4)cccc3)ncccc1 +c1ccc(-c2ccc(-c3c4cc[nH]c4cc4occc34)cn2)nc1 +c1ccc(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cn2)nc1 +c1(c2ncc(cc2)c2cc3c(Sc4c(cccc4)N3)cc2)ncccc1 +c1ccc(-c2ccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)cn2)nc1 +c1ccc(-c2ccc(-c3ccc4c(c3)Oc3ccccc3O4)cn2)nc1 +c1ccc(-c2ccc(-c3ccc4c(c3)[nH]c3ccncc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c3cnc3ccccc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c3[nH]c3cnccc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4cc[nH]c34)cn2)nc1 +c1ccc(-c2ccc(-c3ccnnc3)cn2)nc1 +c1ccc(-c2ccc(-c3cnc4oc5ccccc5c4c3)cn2)nc1 +c1ccc(-c2ccc(-c3cnc4sc5ncccc5c4c3)cn2)nc1 +c1ccc(-c2ccc(-n3c4ccccc4c4c5ccccc5[nH]c43)cn2)nc1 +c1ccc(-c2ccc(-n3c4ccccc4c4cnccc43)cn2)nc1 +c1ccc(-c2ccc3c(c2)[nH]c2cnccc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccc3ccc4cccnc4c3n2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccc3nn[nH]c3c2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc(-c3c4ccoc4cc4ccoc34)n2)nc1 +c1ccc(-c2cccc(-c3c4cc[nH]c4cc4occc34)n2)nc1 +c1ccc(-c2cccc(-c3cc4cc5occc5cc4o3)n2)nc1 +c1ccc(-c2cccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)n2)nc1 +c1(c2ncccc2)nc(ccc1)c1cc2CCc3c(cccc3)Nc2cc1 +c1ccc(-c2cccc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)n2)nc1 +c1ccc(-c2cccc(-c3ccc4cc[nH]c4c3)n2)nc1 +c1ccc(-c2cccc(-c3ccc4ncoc4c3)n2)nc1 +c1ccc(-c2cccc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)n2)nc1 +c1ccc(-c2cccc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)nc1 +c1(c2ncccc2)nc(ccc1)c1c2CCc3c(cccc3)Nc2ccc1 +c1ccc(-c2cccc(-c3cccc4c3oc3ccccc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4oc5ccccc5c34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4ocnc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4sccc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)n2)nc1 +c1ccc(-c2cccc(-c3cccnn3)n2)nc1 +c1ccc(-c2cccc(-c3cnc4oc5ccccc5c4c3)n2)nc1 +c1ccc(-c2cccc(-c3cnc4sc5ccccc5c4c3)n2)nc1 +c1ccc(-c2cccc(-c3coc4cc5ccoc5cc34)n2)nc1 +c1ccc(-c2cccc(-c3coc4nc5[nH]ccc5nc34)n2)nc1 +c1ccc(-c2cccc(-n3c4ccccc4c4c5ccccc5[nH]c43)n2)nc1 +c1ccc(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c2[nH]c2ccncc23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c2[nH]c2ncccc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc3c4ccccc4c4nccnc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3cc[nH]c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3ocnc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc3sc4ncccc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]c4ccncc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]nnc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccn[nH]2)c(-c2cnccn2)c1 +c1ccc(-c2cnc(-c3c4ccoc4cc4ccoc34)cn2)cc1 +c1ccc(-c2cnc(-c3c4ncoc4cc4ncoc34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)Oc3ccccc3O4)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)[nH]c3ccncc34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4cnc5ccccc5c4c3)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4ncsc4c3)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c3cnc3ccccc34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4ncsc34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4oc5ncccc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccnn3)cn2)cc1 +c1ccc(-c2cnc(-c3coc4ccccc34)cn2)cc1 +c1ccc(-c2cnc(-c3c[nH]c4nc5occc5nc34)cn2)cc1 +c1ccc(-c2cnc(-n3ccc4ccccc43)cn2)cc1 +c1ccc(-c2cnc3[nH]c4ccccc4c3c2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cncc(-c3cc4cc5ccoc5cc4[nH]3)n2)cc1 +c1ccc(-c2cncc(-c3cc4cc5occc5cc4o3)n2)cc1 +c1ccc(-c2cncc(-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +c1ccc(-c2cncc(-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)ncc3ccccc34)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)oc3ccccc34)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(cnc5ccccc54)c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4ccsc4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4ncc5ccccc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4sccc4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4[nH]c5ccncc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +c1(c2nc(cnc2)c2c3c(CCc4c(cccc4)N3)ccc2)ccccc1 +c1ccc(-c2cncc(-c3cccc4c3[nH]c3ccncc34)n2)cc1 +c1ccc(-c2cncc(-c3cccc4c5ccccc5c5nccnc5c34)n2)cc1 +c1ccc(-c2cncc(-c3cccc4cnc5ccccc5c34)n2)cc1 +c1ccc(-c2cncc(-c3cnc4sc5ncccc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3cncc4c3[nH]c3ccccc34)n2)cc1 +c1ccc(-c2cncc(-n3c4ccccc4c4c5ccccc5[nH]c43)n2)cc1 +c1ccc(-c2cnccn2)c(-c2ccc3c(c2)c2ccccc2c2nccnc32)c1 +c1ccc(-c2cnccn2)c(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +c1ccc(-c2cnccn2)c(-c2ccc3ccoc3c2)c1 +c1ccc(-c2cnccn2)c(-c2ccc3sccc3c2)c1 +c1ccc(-c2cncs2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2coc3cc4ccoc4cc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cscn2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2c[nH]c3ccccc23)c(-c2cnccn2)c1 +c1ccc(-c2c[nH]c3nc4occc4nc23)c(-c2cnccn2)c1 +c1ccc(-c2nc3ccccc3s2)c(-c2cnccn2)c1 +c1ccc(-c2nccc3[nH]c4ccncc4c23)c(-c2cnccn2)c1 +c1(c2ncccc2N2c3c(CCc4c2cccc4)cccc3)ncccc1 +c1ccc(-c2ncccc2-c2c3ccoc3cc3ccoc23)nc1 +c1ccc(-c2ncccc2-c2cc3ccccc3[nH]2)nc1 +c1ccc(-c2ncccc2-c2cc3nc4ccoc4nc3[nH]2)nc1 +c1ccc(-c2ncccc2-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)nc1 +c1ccc(-c2ncccc2-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)nc1 +c1ccc(-c2ncccc2-c2ccc3c(c2)oc2ccccc23)nc1 +c1ccc(-c2ncccc2-c2ccc3c(cnc4ccccc43)c2)nc1 +c1ccc(-c2ncccc2-c2ccc3ncsc3c2)nc1 +c1ccc(-c2ncccc2-c2ccc3ocnc3c2)nc1 +c1ccc(-c2ncccc2-c2ccc3sccc3c2)nc1 +c1ccc(-c2ncccc2-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)nc1 +c1ccc(-c2ncccc2-c2cccc3c4ccccc4c4nc[nH]c4c23)nc1 +c1ccc(-c2ncccc2-c2cccc3c4ccccc4c4[nH]cnc4c23)nc1 +c1ccc(-c2ncccc2-c2cccc3c4[nH]cnc4c4ccccc4c23)nc1 +c1ccc(-c2ncccc2-c2coc3cc4[nH]ccc4cc23)nc1 +c1ccc(-c2ncccc2-c2c[nH]c3ccccc23)nc1 +c1ccc(-c2ncccc2-c2nc3ccccc3c3ccccc23)nc1 +c1ccc(-c2ncccc2-n2c3ccncc3c3cnccc32)nc1 +c1ccc(-c2ncccc2-n2ccc3cc4ccoc4cc32)nc1 +c1ccc(-c2nccnc2-c2cc3cc4occc4cc3o2)cc1 +c1ccc(-c2nccnc2-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1 +c1ccc(-c2nccnc2-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)cc1 +c1ccc(-c2nccnc2-c2ccc3c4ccccc4c4nccnc4c3c2)cc1 +c1ccc(-c2nccnc2-c2ccc3[nH]c4ccncc4c3c2)cc1 +c1ccc(-c2nccnc2-c2ccc3[nH]ccc3c2)cc1 +c1ccc(-c2nccnc2-c2cccc3c2sc2ncccc23)cc1 +c1ccc(-c2nccnc2-c2cccc3c4nc[nH]c4c4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2cccc3nn[nH]c23)cc1 +c1ccc(-c2nccnc2-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)cc1 +c1ccc(-c2nccnc2-c2cccc3[nH]c4cnccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccccc2N(c2ccccc2)c2ccccc2)cc1 +c1ccc(-c2nccnc2-c2ccnc3oc4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccnc3sc4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccnc3sc4ncccc4c23)cc1 +c1ccc(-c2nccnc2-c2cncc3c2[nH]c2ccncc23)cc1 +c1ccc(-c2nccnc2-c2cn[nH]c2)cc1 +c1ccc(-c2nccnc2-c2nc3ccccc3c3ccccc23)cc1 +c1ccc(-c2nccnc2-n2c3ccccc3c3cnccc32)cc1 +c1ccc(-c2nccnc2-n2c3ccncc3c3cnccc32)cc1 +c1ccc(-c2nccnc2-n2cnc3nc4nc[nH]c4nc32)cc1 +c1ccc(-c2ncno2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c(-c2cnccn2)c1 +c1ccc(-n2c3ccccc3c3cccnc32)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-n2c3ccccc3c3cnccc32)c(-c2cnccn2)c1 +c1ccc(N(c2ccccc2)c2ccc(-c3cc4nc5cc[nH]c5nc4o3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cc4[nH]c5ccncc5c4cn3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4cnc5ccccc5c4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4nn[nH]c4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4[nH]nnc4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc(-c4cnccn4)c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4c3cnc3ccccc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4ocnc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cncc4c3[nH]c3ccncc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3nccc4[nH]c5ccncc5c34)cc2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c(c3)ncc3ccccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c(c3)sc3ccccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc(-c4cnccn4)c3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4c3[nH]c3ncccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4cnc5ccccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4ncoc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4[nH]c5ncccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4[nH]nnc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cnc4[nH]c5ccccc5c4c3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cncc4[nH]c5ccccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cnoc3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3c[nH]c4ccncc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3ccc4cnccc43)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3cnc4nc5nc[nH]c5nc43)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3nnc4ccccc43)c2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2c3ncoc3nc3ocnc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cc3[nH]c4ccncc4c3cn2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccc3c(c2)[nH]c2cnccc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccc3ccc4cccnc4c3n2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cccc3c2B2c4ccccc4Oc4cccc(c42)O3)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cccc3[nH]c4ncccc4c23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccno2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2coc3cc4ccoc4cc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2coc3nc4[nH]ccc4nc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2nc3nc4nc[nH]c4nc3[nH]2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2nccs2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ncno2)cc1 +c1ccc2c(-c3c4ccoc4cc4ccoc34)coc2c1 +c1ccc2c(-c3c4cc[nH]c4cc4occc34)csc2c1 +c1ccc2c(-c3c4ncoc4nc4ocnc34)csc2c1 +c1ccc2c(-c3c4nc[nH]c4cc4[nH]cnc34)csc2c1 +c1ccc2c(-c3c4[nH]cnc4cc4nc[nH]c34)coc2c1 +c1ccc2c(-c3c4[nH]cnc4nc4nc[nH]c34)csc2c1 +c1ccc2c(-c3cc4cnccc4[nH]3)coc2c1 +c1ccc2c(-c3cc4nc5ccoc5nc4[nH]3)coc2c1 +c1ccc2c(-c3cc4nc5cc[nH]c5nc4o3)coc2c1 +c1ccc2c(-c3cc4nc5cc[nH]c5nc4o3)c[nH]c2c1 +c1ccc2c(-c3ccc(-c4cnccn4)cc3)c[nH]c2c1 +c1ccc2c(-c3ccc4c(c3)c3ccccc3c3nccnc43)csc2c1 +c1ccc2c(-c3ccc4c(c3)sc3ncccc34)csc2c1 +c1ccc2c(-c3ccc4ccsc4c3)csc2c1 +c1ccc2c(-c3ccc4ocnc4c3)c[nH]c2c1 +c1ccc2c(-c3ccc4[nH]c5ncccc5c4c3)c[nH]c2c1 +c1ccc2c(-c3ccc4[nH]nnc4c3)coc2c1 +c1ccc2c(-c3cccc4c3[nH]c3cnccc34)csc2c1 +c1ccc2c(-c3cccc4c3[nH]c3ncccc34)coc2c1 +c1ccc2c(-c3cccc4c3[nH]c3ncccc34)csc2c1 +c1ccc2c(-c3cccc4c5nccnc5c5ccccc5c34)csc2c1 +c1ccc2c(-c3cccc4ocnc34)c[nH]c2c1 +c1ccc2c(-c3cccc4sc5ccccc5c34)coc2c1 +c1ccc2c(-c3ccnc4ncccc34)c[nH]c2c1 +c1ccc2c(-c3ccnnc3)csc2c1 +c1ccc2c(-c3cnc4nccnc4n3)coc2c1 +c1ccc2c(-c3cncs3)c[nH]c2c1 +c1ccc2c(-c3coc4cc5ccoc5cc34)c[nH]c2c1 +c1ccc2c(-c3csc4ccccc34)c[nH]c2c1 +c1ccc2c(-c3cscn3)csc2c1 +c1ccc2c(-c3c[nH]c4nc5occc5nc34)coc2c1 +c1ccc2c(-c3nc4cc5ncoc5nc4o3)c[nH]c2c1 +c1ccc2c(-c3nccc4[nH]ccc34)coc2c1 +c1ccc2c(-n3c4ccccc4c4cccnc43)coc2c1 +c1ccc2c(-n3c4ccccc4c4cccnc43)c[nH]c2c1 +c1ccc2c(-n3c4ccccc4c4cnccc43)csc2c1 +c1ccc2c(-n3ccc4nc5ccoc5nc43)c[nH]c2c1 +c1ccc2c(-n3cnc4nc5nc[nH]c5nc43)coc2c1 +c1ccc2c(-n3cnc4nc5nc[nH]c5nc43)c[nH]c2c1 +c12c(ccnc2)[nH]c(c1)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(c3c(cc(nc3)c3c4c(Sc5c(cccc5)N4)ccc3)[nH]2)cncc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +c12c(cccc2)cnc2c1ccc(c2)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(scc1)cc(cc2)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(c(ccc2)c2c3c(Sc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c1(c2nccnc2)ccccc1c1c2c(Sc3c(cccc3)N2)ccc1 +n1oc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +n1c(csc1)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(ccnc2c2c3c(Sc4c(cccc4)N3)ccc2)[nH]cc1 +c12c(scc1)ccc(c2)c1cc2c(Sc3c(cccc3)N2)cc1 +n1c2c(ncc(c2)c2cc3c(Sc4c(cccc4)N3)cc2)ccc1 +c12c(c3c(c(cnc3)c3cc4c(Sc5c(cccc5)N4)cc3)[nH]2)cncc1 +n1c2c(cc3c(nc(c4cc5c(Sc6c(cccc6)N5)cc4)[nH]3)c2)[nH]c1 +n1c2nc3oc(nc3nc2oc1)c1cc2c(Sc3c(cccc3)N2)cc1 +n1ccsc1c1cc2c(Sc3c(cccc3)N2)cc1 +c12c(c3c(n1c1cc4c(Sc5c(cccc5)N4)cc1)ccnc3)cncc2 +c12nc3c(occ3)nc1[nH]c(c2)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(cc(nc2)c2ccc3c(Sc4c(cccc4)N3)c2)[nH]cc1 +c12c(ccc(c2)c2ccc3c(Sc4c(cccc4)N3)c2)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(c(ccc2)c2ccc3c(Sc4c(cccc4)N3)c2)[nH]c2c1ccnc2 +c12c(cccc2c2ccc3c(Sc4c(cccc4)N3)c2)cnc2c1cccc2 +n1oc(cc1)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(ccnc2)[nH]cc1c1ccc2c(Sc3c(cccc3)N2)c1 +n1c2c(n(c1)c1ccc3c(Sc4c(cccc4)N3)c1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +c1(c2nccnc2)ccc(cc1)c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(cc(cc2)c2c3c(ccc2)Nc2c(S3)cccc2)[nH]c2ncccc12 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +n1c2c(oc1)cccc2c1c2c(ccc1)Nc1c(S2)cccc1 +n1occc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(c3c(c(cnc3)c3c4c(ccc3)Nc3c(S4)cccc3)[nH]2)cncc1 +c12c(ccnc2)[nH]cc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(ccc1)Nc1c(S2)cccc1 +n1cnoc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(n(c3c1ccnc3)c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +n1c2c(nc3c(nco3)c2N2c3c(Sc4c2cccc4)cccc3)oc1 +c12c(cc(nc2)N2c3c(Sc4c2cccc4)cccc3)[nH]cc1 +c12c(cc(cc2)N2c3c(Sc4c2cccc4)cccc3)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)N1c2c(Sc3c1cccc3)cccc2 +n1c2c(nc(cc2)N2c3c(Sc4c2cccc4)cccc3)ccc1 +c12c(sc3c1cccc3N1c3c(Sc4c1cccc4)cccc3)cccc2 +n1c2c(oc1)c(ccc2)N1c2c(Sc3c1cccc3)cccc2 +c12c(nn[nH]2)cccc1N1c2c(Sc3c1cccc3)cccc2 +c12c(cccc2N2c3c(Sc4c2cccc4)cccc3)[nH]c2ncccc12 +c12c(nn[nH]2)c(ccc1)N1c2c(Sc3c1cccc3)cccc2 +c1(c2nccnc2)ccccc1N1c2c(Sc3c1cccc3)cccc2 +c12c(cccc2)[nH]c2ncc(cc12)N1c2c(Sc3c1cccc3)cccc2 +c12nc3c(occ3N3c4c(Sc5c3cccc5)cccc4)nc1[nH]cc2 +c12c(ccnc2N2c3c(Sc4c2cccc4)cccc3)[nH]cc1 +c12nc3c(occ3)nc1n(cc2)N1c2c(Sc3c1cccc3)cccc2 +c1ccc2c(c1)c1cc(-c3c4ccoc4cc4ccoc34)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3c4ccoc4cc4ccoc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3c4ncoc4nc4ocnc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3cc4cnccc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3cc4nc5ccoc5nc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3cc4nc5cc[nH]c5nc4o3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3cc4[nH]ccc4cn3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4nn[nH]c4c3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4[nH]nnc4c3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ccon3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3cnc4nccnc4n3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3cscn3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3nc4nc5ocnc5nc4o3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3nccc4[nH]ccc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ncon3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4ccncc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3ccc4nc5ccoc5nc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3cnc4nc5nc[nH]c5cc43)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-n3cnc4nc5nc[nH]c5nc43)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3c4ccoc4cc4ccoc34)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cc4cnccc4[nH]3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3ccc(-c4cnccn4)cc3)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3ccc4c(c3)[nH]c3cnccc34)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3ccc4sccc4c3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3ccc4[nH]nnc4c3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cncc4c3[nH]c3ccncc34)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3cncs3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cnoc3)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3cnoc3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3coc4cc5ccoc5cc34)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nc4cc5ncoc5nc4o3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nc4nc5nc[nH]c5cc4[nH]3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3nc4nc5ocnc5nc4o3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nccs3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-n3c4ccncc4c4cnccc43)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-n3cnc4nc5nc[nH]c5nc43)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-n3cnc4nc5nc[nH]c5nc43)cc1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c4ncoc4nc4ocnc34)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3c4ncoc4nc4ocnc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c4nc[nH]c4cc4[nH]cnc34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3ccc4ncoc4c3)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3ccc4[nH]nnc4c3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3cncs3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3cscn3)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c[nH]c4ccncc34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3c[nH]c4nc5occc5nc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3nc4cc5ncoc5nc4o3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]c5ccncc5c34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]c5ccncc5c34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]ccc34)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]ccc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3ncon3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-n3cnc4cc5nc[nH]c5cc43)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-n3cnc4nc5nc[nH]c5cc43)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-n3cnc4nc5nc[nH]c5nc43)c1c1[nH]cnc21 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1cc2nc3ccoc3nc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1c[nH]c2ccncc12 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nc2nc3nc[nH]c3nc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nccc2[nH]ccc12 +c1ccc2c(c1)c1ccccc1c1nc(-c3cc4cnccc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3cc4[nH]c5ccncc5c4cn3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3ccc(-c4cnccn4)cc3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3c[nH]c4nc5occc5nc34)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3nc4cc5nc[nH]c5cc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3nc4nc5nc[nH]c5cc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3ncno3)cnc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cc4[nH]ccc4cn3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3ccc4ncoc4c3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3ccc4[nH]nnc4c3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cnc4nccnc4n3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cncc4cc[nH]c34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3coc4nc5[nH]ccc5nc34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3c[nH]c4nc5occc5nc34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3nc4cc5nc[nH]c5cc4[nH]3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3nccc4[nH]c5ccncc5c34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-n3cnc4nc5nc[nH]c5cc43)nc21 +c1ccc2c(c1)c1cccnc1n2-c1cc2cc3occc3cc2o1 +c1ccc2c(c1)c1cccnc1n2-c1cc2nc3cc[nH]c3nc2o1 +c1ccc2c(c1)c1cccnc1n2-c1ccc2sccc2c1 +c1ccc2c(c1)c1cccnc1n2-c1ccn[nH]1 +c1ccc2c(c1)c1cccnc1n2-c1c[nH]c2cc3occc3cc12 +c1ccc2c(c1)c1cccnc1n2-c1c[nH]c2nc3occc3nc12 +c1ccc2c(c1)c1ccncc1n2-c1c2cc[nH]c2cc2occc12 +c1ccc2c(c1)c1ccncc1n2-c1cc2cc3cc[nH]c3cc2o1 +c1ccc2c(c1)c1ccncc1n2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)c1ccncc1n2-c1ccn[nH]1 +c1ccc2c(c1)c1ccncc1n2-c1cc[nH]n1 +c1ccc2c(c1)c1ccncc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)c1ccncc1n2-c1c[nH]c2ccncc12 +c1ccc2c(c1)c1ccncc1n2-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1ccncc1n2-n1c2ccccc2c2cccnc21 +c1ccc2c(c1)c1ccncc1n2-n1ccc2cc3ccoc3cc21 +c1ccc2c(c1)c1cnccc1n2-c1ccc2c(c1)[nH]c1cnccc12 +c1ccc2c(c1)c1cnccc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)c1cnccc1n2-c1nc2nc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1cnccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1ccc2c(c1)c1cnccc1n2-n1cnc2nc3nc[nH]c3nc21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3cc4[nH]ccc4cn3)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3ccc4nn[nH]c4c3)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3nccc4[nH]c5ccncc5c34)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-n3ccc4cnccc43)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-n3cnc4nc5nc[nH]c5cc43)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3cncc4cc[nH]c34)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3cnoc3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3nc4nc5ocnc5nc4o3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3ncno3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-n3c4ccncc4c4cnccc43)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3cc4[nH]ccc4cn3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3ccc4ocnc4c3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3ccc4[nH]c5cnccc5c4c3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3cncc4c3[nH]c3ccncc34)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3coc4cc5ccoc5cc34)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-n3ccc4nc5ccoc5nc43)c21 +c12c(occ1)c(c1c(occ1)c2)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2c(nc3c(nco3)c2c2c3CCc4c(cccc4)Nc3ccc2)oc1 +c12c(cc(nc2)c2c3CCc4c(cccc4)Nc3ccc2)[nH]cc1 +c12c(cccc2)[nH]c2nc(ccc12)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2nc(ccc2ccc1)c1c2CCc3c(cccc3)Nc2ccc1 +c12c(ccc(c2)c2c3CCc4c(cccc4)Nc3ccc2)cnc2c1cccc2 +c12c(ccc(c2)c2c3CCc4c(cccc4)Nc3ccc2)[nH]c2c1ccnc2 +c12nccnc1c(ccc2)c1c2CCc3c(cccc3)Nc2ccc1 +n1cc(sc1)c1c2CCc3c(cccc3)Nc2ccc1 +c12nc3c(occ3c3c4CCc5c(cccc5)Nc4ccc3)nc1[nH]cc2 +n1ccsc1c1c2CCc3c(cccc3)Nc2ccc1 +c12c(n(c3ncccc13)c1c3CCc4c(cccc4)Nc3ccc1)cccc2 +c12c(n(c3c1ccnc3)c1c3CCc4c(cccc4)Nc3ccc1)cccc2 +n1c2c(n(c1)c1c3CCc4c(cccc4)Nc3ccc1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2c(cc3c(nc[nH]3)c2c2cc3CCc4c(cccc4)Nc3cc2)[nH]c1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1cc3CCc5c(cccc5)Nc3cc1)cccc4)cccc2 +c1(c2nccnc2)ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(nc(cc2)c2cc3CCc4c(cccc4)Nc3cc2)ccc1 +c12c(ccc(c2)c2cc3CCc4c(cccc4)Nc3cc2)[nH]c2c1ccnc2 +c12c(ccc(c2)c2cc3CCc4c(cccc4)Nc3cc2)[nH]c2ncccc12 +c12c(cccc2)cnc2c1c(ccc2)c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(nccc2)c(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +c12c(cccc2)[nH]c2nccc(c12)c1cc2CCc3c(cccc3)Nc2cc1 +c12c(occ1)cc1c(occ1c1cc3CCc4c(cccc4)Nc3cc1)c2 +c12c(ccnc2)[nH]cc1c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(cc3c(nc(c4cc5CCc6c(cccc6)Nc5cc4)[nH]3)c2)[nH]c1 +c12c(ccnc2c2cc3CCc4c(cccc4)Nc3cc2)[nH]cc1 +n1ccsc1c1cc2CCc3c(cccc3)Nc2cc1 +c12c(nnn1c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +n1c2c(nc3c(nco3)c2c2ccc3CCc4c(cccc4)Nc3c2)oc1 +c12c(cc(cc2)c2ccc3CCc4c(cccc4)Nc3c2)cnc2c1cccc2 +c12c(cccc2)cnc2c1cccc2c1ccc2CCc3c(cccc3)Nc2c1 +c12c(sc3c1c(ccc3)c1ccc3CCc4c(cccc4)Nc3c1)cccc2 +c12c(cccc2c2ccc3CCc4c(cccc4)Nc3c2)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nccc1c1ccc2CCc3c(cccc3)Nc2c1 +n1occc1c1ccc2CCc3c(cccc3)Nc2c1 +n1occ(c1)c1ccc2CCc3c(cccc3)Nc2c1 +n1c(csc1)c1ccc2CCc3c(cccc3)Nc2c1 +c12nc3c(occ3)nc1[nH]cc2c1ccc2CCc3c(cccc3)Nc2c1 +n1c2c(cc3c(nc(c4ccc5CCc6c(cccc6)Nc5c4)[nH]3)c2)[nH]c1 +n1cnoc1c1ccc2CCc3c(cccc3)Nc2c1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c1 +c12nc3c(oc(c3)c3c4c(CCc5c(cccc5)N4)ccc3)nc1[nH]cc2 +c12c(cc(cc2)c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c12c(scc1)cc(cc2)c1c2c(CCc3c(cccc3)N2)ccc1 +n1c2c(oc1)ccc(c2)c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(ccc(c2)c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c12c(c(ccc2)c2c3c(CCc4c(cccc4)N3)ccc2)cnc2c1cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +c12c(c(ccc2)c2c3c(ccc2)CCc2c(cccc2)N3)[nH]c2c1ccnc2 +c12c(sc3c1c(ccc3)c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +c12c(scc1)cccc2c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(cccc2)c(nc2c1cccc2)c1c2c(CCc3c(cccc3)N2)ccc1 +n1c2nc3nc(c4c5c(CCc6c(cccc6)N5)ccc4)[nH]c3cc2[nH]c1 +c12c(cccc2)[nH]c2c1ccnc2c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(CCc3c(cccc3)N2)ccc1 +n1ccsc1c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)N1c3c(CCc5c1cccc5)cccc3)cccc4)cccc2 +c12nc3c(oc(c3)N3c4c(CCc5c3cccc5)cccc4)nc1[nH]cc2 +n1c2c(nc(cc2)N2c3c(CCc4c2cccc4)cccc3)ccc1 +c12c(nn[nH]2)cc(cc1)N1c2c(CCc3c1cccc3)cccc2 +c12c(sc3c1cccc3N1c3c(CCc4c1cccc4)cccc3)cccc2 +c12c(c(ccc2)N2c3c(CCc4c2cccc4)cccc3)[nH]c2ncccc12 +c12c(cccc2N2c3c(CCc4c2cccc4)cccc3)[nH]c2ncccc12 +n1oc(cc1)N1c2c(CCc3c1cccc3)cccc2 +n1c2c(cc3c(nc([nH]3)N3c4c(CCc5c3cccc5)cccc4)c2)[nH]c1 +c12c(cccc2)[nH]c2c1ccnc2N1c2c(CCc3c1cccc3)cccc2 +c12c(c3c(ccnc3)[nH]2)c(ncc1)N1c2c(CCc3c1cccc3)cccc2 +c12c(n(c3c1ccnc3)N1c3c(CCc4c1cccc4)cccc3)cccc2 +c1ccc2c(c1)ccn2-c1c2nc[nH]c2cc2[nH]cnc12 +c1ccc2c(c1)ccn2-c1c2[nH]cnc2cc2nc[nH]c12 +c1ccc2c(c1)ccn2-c1c2[nH]cnc2nc2nc[nH]c12 +c1ccc2c(c1)ccn2-c1ccc2[nH]c3cnccc3c2c1 +c1ccc2c(c1)ccn2-c1cccc2c1sc1ccccc12 +c1ccc2c(c1)ccn2-c1cccc2ocnc12 +c1ccc2c(c1)ccn2-c1cccc2sc3ccccc3c12 +c1ccc2c(c1)ccn2-c1ccno1 +c1ccc2c(c1)ccn2-c1cnc2ccccc2n1 +c1ccc2c(c1)ccn2-c1cnc2[nH]c3ccccc3c2c1 +c1ccc2c(c1)ccn2-c1coc2nc3[nH]ccc3nc12 +c1ccc2c(c1)ccn2-c1nccc2c1[nH]c1ccccc12 +c1ccc2c(c1)cnc1c(-c3cc4[nH]c5ccccc5c4cn3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4c(c3)sc3ccccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4ccsc4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4cc[nH]c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4oc5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4scnc4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cccc4c3[nH]c3ncccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3cccc4c5ccccc5c5nccnc5c34)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4sc5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4[nH]c5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cn[nH]c3)cccc12 +c1ccc2c(c1)cnc1c(-c3coc4ccccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc12 +c1ccc2c(c1)cnc1c(-n3ccc4nc5ccoc5nc43)cccc12 +c1ccc2c(c1)cnc1cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cc4cccnc4c4ncccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3ccncc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c5c3CCCN5CCC4)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ccoc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ccsc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4sccc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]nnc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c3sc3ncccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c3[nH]c3cnccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c5ccccc5c5[nH]cnc5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cnc4c5ccccc5c5ccccc5c4n3)ccc12 +c1ccc2c(c1)cnc1cc(-c3cnc4sc5ncccc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1ccc2c(c1)cnc1cc(-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)ccc12 +c1ccc2c(c1)cnc1cc(-n3cnc4c5ccccc5c5ccccc5c43)ccc12 +c1ccc2c(c1)cnc1ccc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4c(cnc5ccccc54)c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4nn[nH]c4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4occc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4ocnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4[nH]ccc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4c3cnc3ccccc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4ncsc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4sc5ccccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4[nH]c5ncccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnc4c3ccc3cccnc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnc4sc5ccccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnnc3)cc12 +c1ccc2c(c1)cnc1ccc(-c3nc4cc5scnc5cc4s3)cc12 +c1ccc2c(c1)cnc1ccc(-c3nccs3)cc12 +c1ccc2c(c1)cnc1ccc(-n3ccc4cnccc43)cc12 +c1ccc2c(c1)cnc1ccc(-n3cnc4cc5nc[nH]c5cc43)cc12 +c1ccc2c(c1)cnc1cccc(-c3cc4cc5ccoc5cc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3cc4nc5ccoc5nc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4c(c3)sc3ccccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4c(n3)sc3ncccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4[nH]c5ccncc5c4c3)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4[nH]nnc4c3)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c5ccccc5c5nccnc5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4ncc5ccccc5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4occc34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4[nH]ccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccnc4cccnc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccno3)c12 +c1ccc2c(c1)cnc1cccc(-c3cn[nH]c3)c12 +c1ccc2c(c1)cnc1cccc(-c3coc4cc5ccoc5cc34)c12 +c1ccc2c(c1)cnc1cccc(-c3coc4cc5[nH]ccc5cc34)c12 +c1ccc2c(c1)cnc1cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3nc4cc5scnc5cc4s3)c12 +c1ccc2c(c1)cnc1cccc(-n3cnc4c5ccccc5c5ccccc5c43)c12 +c1ccc2c(c1)nc(-c1c3cc[nH]c3cc3occc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3ncoc3nc3ocnc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3ncsc3cc3ncsc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3nc[nH]c3cc3[nH]cnc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cc3c4ccccc4[nH]c3c3c1[nH]c1ccccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cc3nc4cc[nH]c4nc3o1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3c(c1)c1ccccc1c1nccnc31)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3c(c1)[nH]c1c3ccc3[nH]c4ccccc4c31)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3nccnc3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3nn[nH]c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3oc4ccccc4c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3c1[nH]c1ccncc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3c4ccccc4c4nc[nH]c4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3occc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3sccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3[nH]c4ncccc4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1ccnc3oc4ccccc4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1cnc3[nH]c4ccccc4c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1cncc3c1[nH]c1ccccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cn[nH]c1)c1ccccc12 +c1ccc2c(c1)nc(-n1c3ccncc3c3cnccc31)c1ccccc12 +c1ccc2c(c1)ncc1c(-c3c4ccoc4cc4ccoc34)cccc12 +c1ccc2c(c1)ncc1c(-c3c4ncoc4nc4ocnc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cc4cc5occc5cc4o3)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4c(n3)[nH]c3ccccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4nccnc4c3)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4ocnc4c3)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3oc3ncccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3sc3ncccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4[nH]nnc34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccnc4sc5ccccc5c34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccnc4sc5ncccc5c34)cccc12 +c1ccc2c(c1)ncc1c(-c3cc[nH]n3)cccc12 +c1ccc2c(c1)ncc1c(-c3cnoc3)cccc12 +c1ccc2c(c1)ncc1c(-c3cscn3)cccc12 +c1ccc2c(c1)ncc1c(-c3c[nH]c4ccccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3nc4cc5nc[nH]c5cc4[nH]3)cccc12 +c1ccc2c(c1)ncc1c(-c3nccs3)cccc12 +c1ccc2c(c1)ncc1c(-n3c4ccccc4c4c5ccccc5[nH]c43)cccc12 +c1ccc2c(c1)ncc1c(-n3c4ccccc4c4cccnc43)cccc12 +c1ccc2c(c1)ncc1c(-n3ccc4cc5ccoc5cc43)cccc12 +c1ccc2c(c1)ncc1c(-n3cnc4c5ccccc5c5ccccc5c43)cccc12 +c1ccc2c(c1)ncc1cc(-c3c4ccoc4cc4ccoc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3c4ncoc4cc4ncoc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3cc4[nH]c5ccccc5c4cn3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(c3)sc3ncccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(cnc5ccccc54)c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c5c3CCCN5CCC4)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]ccc4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3cccc4[nH]ccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccnc4sc5ccccc5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccnc4[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccon3)ccc12 +c1ccc2c(c1)ncc1cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +c1ccc2c(c1)ncc1ccc(-c3c4[nH]ccc4cc4ccoc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4ccsc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4ncsc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4occc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5ncccc5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3sc3ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3[nH]c3cnccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3[nH]c3ncccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccnc4oc5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cnc4c5ccccc5c5ccccc5c4n3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncc4c3[nH]c3ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncc4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncs3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cnoc3)cc12 +c1ccc2c(c1)ncc1ccc(-c3coc4ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3c[nH]c4ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ncno3)cc12 +c1ccc2c(c1)ncc1ccc(-n3c4ccccc4c4c5ccccc5[nH]c43)cc12 +c1ccc2c(c1)ncc1ccc(-n3c4ccccc4c4cccnc43)cc12 +c1ccc2c(c1)nnn2-c1cc2c3c(c1)CCCN3CCC2 +c1ccc2c(c1)nnn2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)nnn2-c1ccc2c(c1)sc1ccccc12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1ccc3c4ccccc4[nH]c3c12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1cnccc12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1ncccc12 +c1ccc2c(c1)nnn2-c1ccc2cc[nH]c2c1 +c1ccc2c(c1)nnn2-c1ccc2ncoc2c1 +c1ccc2c(c1)nnn2-c1ccc2nn[nH]c2c1 +c1ccc2c(c1)nnn2-c1ccc2oc3ncccc3c2c1 +c1ccc2c(c1)nnn2-c1ccc2sc3ncccc3c2c1 +c1ccc2c(c1)nnn2-c1ccc2scnc2c1 +c1ccc2c(c1)nnn2-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +c1ccc2c(c1)nnn2-c1cccc2c1[nH]c1[nH]c3ccccc3c12 +c1ccc2c(c1)nnn2-c1cccc2c3ccccc3c3[nH]cnc3c12 +c1ccc2c(c1)nnn2-c1cccc2c3nc[nH]c3c3ccccc3c12 +c1ccc2c(c1)nnn2-c1cccc2[nH]c3ccncc3c12 +c1ccc2c(c1)nnn2-c1cnc2[nH]c3ccccc3c2c1 +c1ccc2c(c1)nnn2-c1cncc2[nH]c3ccccc3c12 +c1ccc2c(c1)nnn2-c1coc2cc3ccoc3cc12 +c1ccc2c(c1)nnn2-c1csc2ccccc12 +c1ccc2c(c1)nnn2-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)nnn2-c1nc2cc3ocnc3cc2o1 +c1ccc2c(c1)nnn2-c1nccc2[nH]ccc12 +c1ccc2c(c1)nnn2-n1c2ccccc2c2c3[nH]c4ccccc4c3ccc21 +c1ccc2c(c1)nnn2-n1cccn1 +c1ccc2c(c1)nnn2-n1cnc2c3ccccc3c3ccccc3c21 +c1ccc2c(c1)nnn2-n1cnc2nc3nc[nH]c3nc21 +c1ccc2c(c1)oc1c(-c3c4ncoc4nc4ocnc34)cccc12 +c1ccc2c(c1)oc1c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc12 +c1ccc2c(c1)oc1c(-c3c4[nH]cnc4nc4nc[nH]c34)cccc12 +c1ccc2c(c1)oc1c(-c3cc4[nH]c5ccncc5c4cn3)cccc12 +c1ccc2c(c1)oc1c(-c3ccc4nn[nH]c4c3)cccc12 +c1ccc2c(c1)oc1c(-c3cncc4c3[nH]c3ccncc34)cccc12 +c1ccc2c(c1)oc1c(-c3csc4ccccc34)cccc12 +c1ccc2c(c1)oc1c(-c3c[nH]c4nc5occc5nc34)cccc12 +c1ccc2c(c1)oc1c(-n3ccc4cnccc43)cccc12 +c1ccc2c(c1)oc1cc(-c3cc4cnccc4[nH]3)ccc12 +c1ccc2c(c1)oc1cc(-c3ccc(-c4cnccn4)cc3)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccc4c(n3)oc3ccccc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4c5c3CCCN5CCC4)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4c5ccccc5c5[nH]cnc5c4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4oc5ncccc5c4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4ocnc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4scnc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3ccc4[nH]c5ncccc5c4c3)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccc4[nH]ccc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cccc4ccsc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3ccnc4ncccc34)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccnc4oc5ccccc5c34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cc[nH]n3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3cncs3)ccc12 +c1ccc2c(c1)Oc1cc(-c3cn[nH]c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3csc4ccccc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3c[nH]c4nc5occc5nc34)ccc12 +c1ccc2c(c1)oc1cc(-c3nc4cc5nc[nH]c5cc4[nH]3)ccc12 +c1ccc2c(c1)oc1cc(-c3ncon3)ccc12 +c1ccc2c(c1)oc1cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +c1ccc2c(c1)Oc1ccc(-c3c4ncoc4cc4ncoc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3c4ncoc4nc4ocnc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3c4[nH]cnc4nc4nc[nH]c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cc4c5c(c3)Oc3ccccc3B5c3ccccc3O4)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cc4cc5ccoc5cc4[nH]3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)oc1ccc(-c3cc4cnccc4[nH]3)cc12 +c1ccc2c(c1)oc1ccc(-c3cc4[nH]c5ccncc5c4cn3)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3ccc4ccoc4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3ccc4ncc5ccccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccc4sccc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3ccc4[nH]c5cnccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccc4[nH]c5ncccc5c4c3)cc12 +c1ccc2c(c1)oc1ccc(-c3cccc4c3[nH]c3cnccc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3cccc4c3[nH]c3cnccc34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cccc4ncc5ccccc5c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cccc4ncoc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cccc4nn[nH]c34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3cccc4sc5ccccc5c34)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccnc4cccnc34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3ccnc4sc5ncccc5c34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccno3)cc12 +c1ccc2c(c1)Oc1ccc(-c3cc[nH]n3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cnc4cccnc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4ncccc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4nccnc4n3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4sc5ccccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cnc4[nH]c5ccccc5c4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3c[nH]c4nc5occc5nc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3c[nH]c4nc5occc5nc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3nc4ccccc4s3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3nccc4c3[nH]c3ccccc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3nccc4[nH]ccc34)cc1O2 +c1ccc2c(c1)oc1ccc(-c3ncno3)cc12 +c1ccc2c(c1)Oc1ccc(-n3c4ccncc4c4cnccc43)cc1O2 +c1ccc2c(c1)oc1cccc(-c3c4ccoc4cc4ccoc34)c12 +c1ccc2c(c1)Oc1cccc(-c3cc4nc5cc[nH]c5nc4o3)c1O2 +c1ccc2c(c1)oc1cccc(-c3cc4[nH]c5ccncc5c4cn3)c12 +c1ccc2c(c1)oc1cccc(-c3cc4[nH]ccc4cn3)c12 +c1ccc2c(c1)Oc1cccc(-c3ccc4c(n3)[nH]c3ccccc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccc4ccsc4c3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccc4ncc5ccccc5c4c3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)Oc1cccc(-c3ccc4[nH]c5cnccc5c4c3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cccc4ocnc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cccc4sccc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccccc3-c3cnccn3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ccnc4ncccc34)c12 +c1ccc2c(c1)oc1cccc(-c3ccon3)c12 +c1ccc2c(c1)Oc1cccc(-c3cncc4c3[nH]c3ccncc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cscn3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3nc4nc5nc[nH]c5cc4[nH]3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3nc4nc5ocnc5nc4o3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ncon3)c12 +c1ccc2c(c1)oc1cccc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)Oc1cccc(-n3cnc4nc5nc[nH]c5nc43)c1O2 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cc2c(cn1)[nH]c1ccccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cc2ccccc2o1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2c(c1)[nH]c1c2ccc2[nH]c4ccccc4c21)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2nn[nH]c2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2oc4ccccc4c2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2[nH]ccc2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c1oc1ccccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c1oc1ncccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c4ccccc4c4nc[nH]c4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2oc4ncccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2[nH]c4cnccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2[nH]c4[nH]c5ccccc5c4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccccc1-c1cc2c4c(c1)CCCN4CCC2)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccnc2sc4ncccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cn[nH]c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1c[nH]c2cc4occc4cc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-n1c2ccccc2c2cnccc21)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(c2)oc2ccccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(n2)sc2ccccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(n2)sc2ncccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4ncsc4c2)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4c5ccccc5c5nc[nH]c5c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4ncc5ccccc5c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4nn[nH]c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2coc4cc5ccoc5cc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4cc5ccoc5cc4[nH]2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4cc5occc5cc4o2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4ccccc4s2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2ccc4c(c2)[nH]c2[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2ncc2ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2oc2ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2[nH]c2c4ccc4[nH]c5ccccc5c42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2[nH]c2ccncc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c5ccccc5c5nc[nH]c5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc[nH]n2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cncc4[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2coc4cc5ccoc5cc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2coc4ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2nc4ccccc4s2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2c4ccccc4c4c5ccccc5[nH]c42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2c4ccncc4c4cnccc42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2ccc4nc5ccoc5nc42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccc4c(c2)[nH]c2c4ccc4[nH]c5ccccc5c42)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4oc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4ocnc24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4sc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4[nH]ccc24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccnc4sc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cc[nH]n2)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2nccc4[nH]c5ccccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-n2c4ccncc4c4cnccc42)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-n2cnc4c5ccccc5c5ccccc5c42)c1O3 +c1ccc2c(c1)oc1nc(-c3cc4cnccc4[nH]3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc(-c4cnccn4)cc3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4sc5ccccc5c4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4[nH]c5ncccc5c4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3cccc4c3sc3ccccc34)ccc12 +c1ccc2c(c1)oc1nc(-c3nccs3)ccc12 +c1ccc2c(c1)oc1ncc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)oc1ncc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)oc1ncc(-c3cc4nc5ccoc5nc4[nH]3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccc4[nH]c5cnccc5c4c3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccno3)cc12 +c1ccc2c(c1)oc1ncc(-c3cnc4nccnc4n3)cc12 +c1ccc2c(c1)oc1ncc(-c3nc4cc5ncoc5nc4o3)cc12 +c1ccc2c(c1)oc1ncc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)oc1ncc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)oc1nccc(-c3c4[nH]cnc4nc4nc[nH]c34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4c(c3)[nH]c3ncccc34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4ocnc4c3)c12 +c1ccc2c(c1)oc1nccc(-c3cncc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)oc1nccc(-c3ncno3)c12 +c1ccc2c(c1)oc1nccc(-n3ccc4nc5ccoc5nc43)c12 +c1ccc2c(c1)oc1nccc(-n3cnc4cc5nc[nH]c5cc43)c12 +c1ccc2c(c1)sc1c(-c3c4[nH]ccc4cc4ccoc34)cccc12 +c1ccc2c(c1)sc1c(-c3cc4c5c(c3)CCCN5CCC4)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4c(c3)c3ccccc3c3nccnc43)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4ccoc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4occc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4[nH]nnc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3cccc4c3[nH]c3ccncc34)cccc12 +c1ccc2c(c1)sc1c(-c3cc[nH]n3)cccc12 +c1ccc2c(c1)sc1c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +c1ccc2c(c1)sc1c(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cccc12 +c1ccc2c(c1)sc1c(-c3nc4cc5scnc5cc4s3)cccc12 +c1ccc2c(c1)sc1c(-c3nccc4[nH]c5ccncc5c34)cccc12 +c1ccc2c(c1)sc1c(-n3c4ccccc4c4ccncc43)cccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ccsc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4nn[nH]c4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4scnc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4[nH]ccc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)ccc12 +c1ccc2c(c1)sc1cc(-c3cccc4c5[nH]cnc5c5ccccc5c34)ccc12 +c1ccc2c(c1)sc1cc(-c3cn[nH]c3)ccc12 +c1ccc2c(c1)sc1cc(-c3nccc4[nH]c5ccncc5c34)ccc12 +c1ccc2c(c1)sc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4c(n3)sc3ccccc34)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4c(n3)sc3ncccc34)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4[nH]c5ccncc5c4c3)cc12 +c1ccc2c(c1)sc1ccc(-c3cccc4c5nc[nH]c5c5ccccc5c34)cc12 +c1ccc2c(c1)sc1ccc(-n3c4ccncc4c4cnccc43)cc12 +c1ccc2c(c1)sc1cccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)c12 +c1ccc2c(c1)sc1cccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)sc1cccc(-c3cccc4c5nccnc5c5ccccc5c34)c12 +c1ccc2c(c1)sc1cccc(-c3c[nH]c4nc5occc5nc34)c12 +c1ccc2c(c1)sc1cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c12 +c1ccc2c(c1)sc1cccc(-n3c4ccncc4c4cnccc43)c12 +c1ccc2c(c1)sc1nc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +c1ccc2c(c1)sc1nc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)sc1nc(-c3ccc4[nH]nnc4c3)ccc12 +c1ccc2c(c1)sc1nc(-c3ccno3)ccc12 +c1ccc2c(c1)sc1nc(-c3cnc4nccnc4n3)ccc12 +c1ccc2c(c1)sc1nc(-c3cnoc3)ccc12 +c1ccc2c(c1)sc1nc(-c3nc4nc5nc[nH]c5nc4[nH]3)ccc12 +c1ccc2c(c1)sc1nc(-c3nccc4[nH]c5ccncc5c34)ccc12 +c1ccc2c(c1)sc1nc(-c3nccc4[nH]ccc34)ccc12 +c1ccc2c(c1)sc1ncc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)sc1ncc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)sc1ncc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)sc1ncc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)sc1ncc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)sc1ncc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)sc1ncc(-c3ncno3)cc12 +c1ccc2c(c1)sc1ncc(-n3cnc4cc5nc[nH]c5cc43)cc12 +c1ccc2c(c1)sc1ncc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)sc1nccc(-c3c4nc[nH]c4cc4[nH]cnc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccc(-c4cnccn4)cc3)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4ocnc4c3)c12 +c1ccc2c(c1)sc1nccc(-c3cccc4c3[nH]c3ncccc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccon3)c12 +c1ccc2c(c1)sc1nccc(-c3cnc4nccnc4n3)c12 +c1ccc2c(c1)sc1nccc(-c3nc4cc5ncoc5nc4o3)c12 +c1ccc2c(c1)sc1nccc(-n3c4ccccc4c4ccncc43)c12 +c1ccc2c(c1)sc1nccc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)sc1nccc(-n3cnc4nc5nc[nH]c5nc43)c12 +c1ccc2c(c1)[nH]c1c(-c3c4cc[nH]c4cc4occc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cc4cc5occc5cc4o3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cc4[nH]ccc4cn3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4c(c3)[nH]c3ncccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4c(n3)sc3ccccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4ccoc4c3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4ccsc4c3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4[nH]nnc4c3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4c3[nH]c3ncccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4c5[nH]cnc5c5ccccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4[nH]c5ncccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccnc4oc5ccccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccnc4[nH]c5ccccc5c34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3ccnnc3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cncs3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3coc4cc5[nH]ccc5cc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3coc4nc5[nH]ccc5nc34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3cscn3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3c[nH]c4ccncc34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3c[nH]c4nc5occc5nc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nc4cc5nc[nH]c5cc4[nH]3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3nc4cc5ocnc5cc4o3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nc4nc5nc[nH]c5cc4[nH]3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nccs3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3nccs3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ncon3)cncc12 +c1ccc2c(c1)[nH]c1c(-n3cnc4nc5nc[nH]c5cc43)nccc12 +c1ccc2c(c1)[nH]c1c2c(-c2c3[nH]cnc3cc3nc[nH]c23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2ccc3ccsc3c2)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2cccc3c2sc2ccccc23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2cccc3[nH]c4ncccc4c23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2nccs2)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-n2ccc3cnccc32)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-n2cnc3nc4nc[nH]c4nc32)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1c2[nH]cnc2nc2nc[nH]c12 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1ccno1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1ccon1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cnc2nccnc2n1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cncc2c1[nH]c1ccncc12 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cscn1 +c1ccc2c(c1)[nH]c1c2cc(-c2c3[nH]cnc3cc3nc[nH]c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3c(c2)[nH]c2cnccc23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3c(c2)[nH]c2ncccc23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3ccsc3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3nccnc3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3nn[nH]c3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccnc3[nH]c4ccccc4c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2cncc3cc[nH]c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-n2cnc3nc4nc[nH]c4nc32)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccc2[nH]nnc2c1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cccc2c1sc1ccccc12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccnc2ncccc12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccno1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cncs1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1nc2nc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1nc2nc3ocnc3nc2o1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ncon1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-n1cnc2cc3nc[nH]c3cc21 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4c5ncoc5nc5ocnc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ccc5c(c4)sc4ccccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ccc5sccc5c4)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4cccc5c4[nH]c4cnccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4cccc5[nH]c6cnccc6c45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4csc5ccccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4c[nH]c5ccncc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ncno4)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-n4ccc5nc6ccoc6nc54)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cc5cc6occc6cc5o4)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cccc5ocnc45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cccc5[nH]c6cnccc6c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4ccnc5ncccc45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4ccnc5[nH]c6ccccc6c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cncc5cc[nH]c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4nccs4)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-n4c5ccncc5c5cnccc54)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4c5ccoc5cc5ccoc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4ccc5[nH]c6cnccc6c5c4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5c4[nH]c4ncccc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5sc6ccccc6c45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5[nH]c6ncccc6c45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cncc5c4[nH]c4ccncc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cncs4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cnoc4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cscn4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4nc5nc6nc[nH]c6cc5[nH]4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4ncon4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-n4c5ccccc5c5ccncc54)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-n4ccc5nc6ccoc6nc54)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cc5nc6ccoc6nc5[nH]4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4ccc5ccsc5c4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4ccc5ncoc5c4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cccc5c4[nH]c4ncccc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cncc5c4[nH]c4ccncc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4csc5ccccc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-n4cnc5nc6nc[nH]c6nc54)c3c21 +c1ccc2c(c1)[nH]c1cc(-c3cc4cc5occc5cc4o3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3ccc4ncoc4c3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3ccc4ocnc4c3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3cncc4cc[nH]c34)ncc12 +c1ccc2c(c1)[nH]c1cc(-n3c4ccccc4c4ccncc43)ncc12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5cc6[nH]ccc6cn5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccc6c(c5)[nH]c5cnccc56)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccc6ccsc6c5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccno5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccon5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5nccs5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cc6nc7ccoc7nc6[nH]5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5ccc6ccsc6c5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5sc5ccccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5[nH]c5cnccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5[nH]c5ncccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cnoc5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5nc6nc7nc[nH]c7nc6[nH]5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5nccc6[nH]c7ccncc7c56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5ncon5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-n5cnc6nc7nc[nH]c7cc65)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5cccc6sccc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5cncc6c5[nH]c5ccncc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5coc6cc7ccoc7cc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-n5c6ccncc6c6cnccc65)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-n5ccc6cnccc65)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5c6nc[nH]c6cc6[nH]cnc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5c6[nH]cnc6nc6nc[nH]c56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6c(c5)sc5ccccc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6nn[nH]c6c5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6[nH]nnc6c5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5cccc6sccc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5coc6nc7[nH]ccc7nc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ncno5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-n5cnc6cc7nc[nH]c7cc65)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-n5cnc6nc7nc[nH]c7cc65)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4c5ncoc5nc5ocnc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4cc5cnccc5[nH]4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5c(c4)[nH]c4cnccc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5[nH]c6ncccc6c5c4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5[nH]nnc5c4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4csc5ccccc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-n4cnc5cc6nc[nH]c6cc54)c3c12 +c1ccc2c(c1)[nH]c1ccnc(-c3c4nc[nH]c4cc4[nH]cnc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cccc4c3sc3ccccc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cccc4[nH]c5cnccc5c34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccnc4[nH]c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccno3)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cscn3)c12 +c1ccc2c(c1)[nH]c1ccnc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)[nH]c1cnc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cc4c5c(c3)CCCN5CCC4)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)oc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)sc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)sc3ncccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(n3)[nH]c3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c5ccccc5c5nccnc5c4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4ccsc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4sc5ccccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4sccc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4c3oc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccnc4sc5ncccc5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cnc4nccnc4n3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ncno3)cc12 +c1ccc2c(c1)[nH]c1cnc(-n3c4ccncc4c4cnccc43)cc12 +c1ccc2c(c1)[nH]c1cnc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)[nH]c1cncc(-c3c4ncoc4nc4ocnc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cc4cc5occc5cc4o3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cc4[nH]ccc4cn3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4c(c3)sc3ccccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4ccsc4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4cc[nH]c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4oc5ccccc5c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4[nH]c5ccncc5c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4[nH]ccc4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cccc4c3[nH]c3ncccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cccc4scnc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cncs3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3csc4ccccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cscn3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3nc4nc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)[nH]c1cncc(-n3c4ccccc4c4cccnc43)c12 +c1ccc2c(c1)[nH]c1cncc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4c(n3)sc3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4oc5ncccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4c3oc3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4occc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4ocnc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccnc4sc5ncccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cnc4sc5ccccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cnc4sc5ncccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3nccc4c3[nH]c3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3nccc4[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)ccc12 +c1ccc2c(c1)[nH]c1ncc(-c3c4ncoc4cc4ncoc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c(c3)[nH]c3ccncc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c5ccccc5c5nccnc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4ncsc4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4sc5ncccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cnc4oc5ccccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cncc4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cn[nH]c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3coc4nc5[nH]ccc5nc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-n3ccc4nc5ccoc5nc43)cc12 +c1ccc2c(c1)[nH]c1ncc(-n3cccn3)cc12 +c1ccc2c(c1)[nH]c1nccc(-c3cc4cc5occc5cc4o3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4cc[nH]c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c3oc3ccccc34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4occc34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4[nH]c5cnccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cnc4oc5ccccc5c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cncc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)[nH]c1nccc(-n3c4ccccc4c4c5ccccc5[nH]c43)c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4c5[nH]cnc5cc5nc[nH]c45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cc5cnccc5[nH]4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4ccc5c(c4)[nH]c4cnccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4ccc5c(c4)[nH]c4ncccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cccc5sccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4coc5nc6[nH]ccc6nc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cscn4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4nc5nc6nc[nH]c6cc5[nH]4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4cc5[nH]ccc5cn4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5c(c4)sc4ccccc45)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5nn[nH]c5c4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5[nH]c6ncccc6c5c4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4coc5cc6ccoc6cc45)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5cc6ncoc6nc5o4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5cc6nc[nH]c6cc5[nH]4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5nc6nc[nH]c6cc5[nH]4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nc5cc6nc[nH]c6cc5[nH]4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nc5nc6ocnc6nc5o4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nccs4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4ncon4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-n4c5ccccc5c5cccnc54)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5nccnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5ocnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5[nH]nnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4cnoc4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4coc5nc6[nH]ccc6nc45)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-n4c5ccncc5c5cnccc54)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-n4cnc5nc6nc[nH]c6cc54)c3c12 +c1ccc2nc(-c3ccc4c5ccccc5c5nccnc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4cnc5ccccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4ncsc4c3)cnc2c1 +c1ccc2nc(-c3ccc4oc5ccccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4sc5ncccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4[nH]ccc4c3)cnc2c1 +c1ccc2nc(-c3cccc4c3sc3ncccc34)cnc2c1 +c1ccc2nc(-c3cccc4c3[nH]c3cnccc34)cnc2c1 +c1ccc2nc(-c3cccc4ncoc34)cnc2c1 +c1ccc2nc(-c3cccc4ocnc34)cnc2c1 +c1ccc2nc(-c3cccc4[nH]c5cnccc5c34)cnc2c1 +c1ccc2nc(-c3coc4cc5[nH]ccc5cc34)cnc2c1 +c1ccc2nc(-c3c[nH]c4cc5occc5cc34)cnc2c1 +c1ccc2nc(-n3c4ccccc4c4cnccc43)cnc2c1 +c1ccc2nc(-n3ccc4cc5ccoc5cc43)cnc2c1 +c1ccc2nc(-n3cccn3)cnc2c1 +c1ccc2oc(-c3c4nc[nH]c4cc4[nH]cnc34)cc2c1 +c1ccc2oc(-c3cc4c(cn3)[nH]c3ccccc34)cc2c1 +c1ccc2oc(-c3cc4c(cn3)[nH]c3ccccc34)nc2c1 +c1ccc2oc(-c3cc4cc5occc5cc4o3)cc2c1 +c1ccc2oc(-c3cc4nc5ccoc5nc4[nH]3)nc2c1 +c1ccc2oc(-c3ccc(-c4cnccn4)cc3)nc2c1 +c1ccc2oc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)nc2c1 +c1ccc2oc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)nc2c1 +c1ccc2oc(-c3ccc4c(c3)[nH]c3cnccc34)nc2c1 +c1ccc2oc(-c3ccc4c(n3)oc3ccccc34)nc2c1 +c1ccc2oc(-c3ccc4c(n3)sc3ncccc34)nc2c1 +c1ccc2oc(-c3ccc4ccsc4c3)nc2c1 +c1ccc2oc(-c3ccc4cc[nH]c4c3)nc2c1 +c1ccc2oc(-c3ccc4cnc5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3ccc4ncccc4n3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5cnccc5c4c3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5ncccc5c4c3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)nc2c1 +c1ccc2oc(-c3cccc4c5nc[nH]c5c5ccccc5c34)nc2c1 +c1ccc2oc(-c3cccc4oc5ccccc5c34)nc2c1 +c1ccc2oc(-c3cccc4ocnc34)nc2c1 +c1ccc2oc(-c3cccc4sccc34)nc2c1 +c1ccc2oc(-c3cccc4[nH]c5ccncc5c34)nc2c1 +c1ccc2oc(-c3cccc4[nH]c5ncccc5c34)cc2c1 +c1ccc2oc(-c3cccc4[nH]c5ncccc5c34)nc2c1 +c1ccc2oc(-c3ccn[nH]3)nc2c1 +c1ccc2oc(-c3cnc4ccccc4n3)cc2c1 +c1ccc2oc(-c3cnc4oc5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3cnc4[nH]c5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3c[nH]c4ccccc34)nc2c1 +c1ccc2oc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)nc2c1 +c1ccc2oc(-c3ncon3)cc2c1 +c1ccc2oc(-n3cnc4nc5nc[nH]c5cc43)cc2c1 +c1ccc2oc(-n3nnc4ccccc43)nc2c1 +c1ccc2sc(-c3c4ncoc4cc4ncoc34)cc2c1 +c1ccc2sc(-c3ccc4c(c3)oc3ncccc34)cc2c1 +c1ccc2sc(-c3ccc4c(c3)sc3ncccc34)cc2c1 +c1ccc2sc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)cc2c1 +c1ccc2sc(-c3ccc4[nH]nnc4c3)nc2c1 +c1ccc2sc(-c3cccc4c3sc3ccccc34)nc2c1 +c1ccc2sc(-c3cccc4occc34)cc2c1 +c1ccc2sc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)cc2c1 +c1ccc2sc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc2c1 +c1ccc2sc(-c3ccnc4sc5ncccc5c34)cc2c1 +c1ccc2sc(-c3cnc4c5ccccc5c5ccccc5c4n3)cc2c1 +c1ccc2sc(-c3cnc4cccnc4c3)cc2c1 +c1ccc2sc(-c3c[nH]c4ccccc34)cc2c1 +c1ccc2sc(-c3c[nH]c4ccncc34)nc2c1 +c1ccc2sc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cc2c1 +c1ccc2sc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc2c1 +c1ccc2sc(-c3nc4nc5nc[nH]c5nc4[nH]3)nc2c1 +c1ccc2sc(-c3nccc4[nH]ccc34)cc2c1 +c1ccc2sc(-n3ccc4cc5ccoc5cc43)cc2c1 +c1ccc2[nH]c(-c3c4ncoc4nc4ocnc34)cc2c1 +c1ccc2[nH]c(-c3cc4cccnc4c4ncccc34)cc2c1 +c1ccc2[nH]c(-c3cc4cnccc4[nH]3)cc2c1 +c1ccc2[nH]c(-c3cc4nc5ccoc5nc4[nH]3)cc2c1 +c1ccc2[nH]c(-c3ccc(-c4cnccn4)cc3)cc2c1 +c1ccc2[nH]c(-c3ccc4c(cnc5ccccc54)c3)cc2c1 +c1ccc2[nH]c(-c3ccc4ocnc4c3)cc2c1 +c1ccc2[nH]c(-c3cccc4c3[nH]c3cnccc34)cc2c1 +c1ccc2[nH]c(-c3cccc4c3[nH]c3ncccc34)cc2c1 +c1ccc2[nH]c(-c3cccc4[nH]c5cnccc5c34)cc2c1 +c1ccc2[nH]c(-c3cccc4[nH]nnc34)cc2c1 +c1ccc2[nH]c(-n3cnc4nc5nc[nH]c5nc43)cc2c1 +c1cnc(-c2ccc(-c3cc4cc5occc5cc4o3)cc2)cn1 +c1cnc(-c2ccc(-c3ccc4[nH]c5ccncc5c4c3)cc2)cn1 +c1cnc(-c2ccc(-n3cnc4nc5nc[nH]c5nc43)cc2)cn1 +c1cnc2c(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3ccncc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3cnccc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccnc2c1 +c1cnc2c(-c3ccc4c5ccccc5c5[nH]cnc5c4c3)ccnc2c1 +c1cnc2c(-c3ccc4ccsc4c3)ccnc2c1 +c1cnc2c(-c3ccc4cc[nH]c4c3)ccnc2c1 +c1cnc2c(-c3ccc4sccc4c3)ccnc2c1 +c1cnc2c(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccnc2c1 +c1cnc2c(-c3ccc4[nH]nnc4c3)ccnc2c1 +c1cnc2c(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)ccnc2c1 +c1cnc2c(-c3cccc4c3[nH]c3cnccc34)ccnc2c1 +c1cnc2c(-c3cccc4c5ccccc5c5nccnc5c34)ccnc2c1 +c1cnc2c(-c3cccc4ncoc34)ccnc2c1 +c1cnc2c(-c3cnc4oc5ccccc5c4c3)ccnc2c1 +c1cnc2c(-c3cncc4c3[nH]c3ccccc34)ccnc2c1 +c1cnc2c(-n3c4ccncc4c4cnccc43)ccnc2c1 +c1cnc2c(c1)cc(-c1c3ncoc3cc3ncoc13)c1cccnc12 +c1cnc2c(c1)cc(-c1c3[nH]ccc3cc3ccoc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cc3nc4ccoc4nc3[nH]1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3c4ccccc4c4nc[nH]c4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3oc4ccccc4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3ocnc3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3sccc3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3[nH]c4[nH]c5ccccc5c4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3c1cnc1ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3c4nccnc4c4ccccc4c13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3ocnc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3[nH]c4[nH]c5ccccc5c4c13)c1cccnc12 +c1cnc2c(c1)cc(-c1cncc3c1[nH]c1ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1nc3ccccc3c3ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1nc3ccccc3s1)c1cccnc12 +c1cnc2c(c1)cc(-n1c3ccccc3c3c4[nH]c5ccccc5c4ccc31)c1cccnc12 +c1cnc2c(c1)cc(-n1nnc3ccccc31)c1cccnc12 +c1cnc2c(c1)ccc1c(-c3cc4cc5occc5cc4o3)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(cnc5ccccc54)c3)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4cnc5ccccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4ncoc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4oc5ncccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4sc5ncccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]c5ccncc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]ccc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccnnc3)ccnc12 +c1cnc2c(c1)ccc1c(-c3cncc4c3[nH]c3ccncc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3nc4cc5ocnc5cc4o3)ccnc12 +c1cnc2c(c1)ccc1c(-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)ccnc12 +c1cnc2c(c1)ccc1cc(-c3c4ncsc4cc4ncsc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3c4[nH]ccc4cc4ccoc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c5c3CCCN5CCC4)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c5ccccc5c5nccnc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4ncsc4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4sccc4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4[nH]c5ccncc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3cccc4[nH]c5ccncc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cccc4[nH]c5cnccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccnc4sc5ccccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cnc4sc5ncccc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3c[nH]c4ccccc34)cnc12 +c1cnc2c(c1)ccc1cc(-n3ccc4ccccc43)cnc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4cnc5ccccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4ocnc4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4sc5ncccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4[nH]c5cnccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4c3[nH]c3ccncc34)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4nn[nH]c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccnc4sc5ncccc5c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3coc4ccccc34)nc12 +c1cnc2c(c1)ccc1ccc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)nc12 +c1cnc2c(c1)ccc1ccc(-c3nc4ccccc4o3)nc12 +c1cnc2c(c1)ccc1ccc(-n3ccc4cc5ccoc5cc43)nc12 +c1cnc2c(c1)ccc1ccc(-n3ccc4ccccc43)nc12 +c1cnc2c(c1)ccc1ccc(-n3nnc4ccccc43)nc12 +c1cnc2cc(-c3c4ncoc4cc4ncoc34)ccc2n1 +c1cnc2cc(-c3c4ncoc4cc4ncoc34)cnc2c1 +c1cnc2cc(-c3c4[nH]ccc4cc4ccoc34)ccc2n1 +c1cnc2cc(-c3cc4cc5ccoc5cc4[nH]3)ccc2n1 +c1cnc2cc(-c3cc4nc5ccoc5nc4[nH]3)cnc2c1 +c1cnc2cc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)cnc2c1 +c1cnc2cc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)cnc2c1 +c1cnc2cc(-c3ccc4occc4c3)cnc2c1 +c1cnc2cc(-c3ccc4ocnc4c3)ccc2n1 +c1cnc2cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cnc2c1 +c1cnc2cc(-c3cccc4ncoc34)cnc2c1 +c1cnc2cc(-c3cncc4[nH]c5ccccc5c34)cnc2c1 +c1cnc2cc(-c3coc4nc5[nH]ccc5nc34)ccc2n1 +c1cnc2cc(-c3coc4nc5[nH]ccc5nc34)cnc2c1 +c1cnc2cc(-c3nc4ccccc4s3)cnc2c1 +c1cnc2cc(-c3nccc4[nH]c5ccccc5c34)cnc2c1 +c1cnc2cc(-n3ccc4nc5ccoc5nc43)ccc2n1 +c1cnc2ccc(-c3c4ccoc4cc4ccoc34)nc2c1 +c1cnc2ccc(-c3c4cc[nH]c4cc4occc34)nc2c1 +c1cnc2ccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)nc2c1 +c1cnc2ccc(-c3ccc4nn[nH]c4c3)nc2c1 +c1cnc2ccc(-c3ccc4oc5ncccc5c4c3)nc2c1 +c1cnc2ccc(-c3ccc4scnc4c3)nc2c1 +c1cnc2ccc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)nc2c1 +c1cnc2ccc(-c3ccc4[nH]ccc4c3)nc2c1 +c1cnc2ccc(-c3cccc4oc5ccccc5c34)nc2c1 +c1cnc2ccc(-c3cccc4ocnc34)nc2c1 +c1cnc2ccc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)nc2c1 +c1cnc2ccc(-c3ccnnc3)nc2c1 +c1cnc2ccc(-c3cncc4c3[nH]c3ccncc34)nc2c1 +c1cnc2ccc(-c3coc4nc5[nH]ccc5nc34)nc2c1 +c1cnc2ccc(-c3c[nH]c4cc5occc5cc34)nc2c1 +c1cnc2ccc(-c3nc4ccccc4s3)nc2c1 +c1cnc2ccc(-n3c4ccccc4c4cnccc43)nc2c1 +c1cnc2nc(-c3c4cc[nH]c4cc4occc34)cnc2n1 +c1cnc2nc(-c3cc4cc5ccoc5cc4[nH]3)cnc2n1 +c1cnc2nc(-c3cc4nc5ccoc5nc4[nH]3)cnc2n1 +c1cnc2nc(-c3ccc4c(n3)sc3ncccc34)ccc2c1 +c1cnc2nc(-c3ccc4ncc5ccccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4ncsc4c3)cnc2n1 +c1cnc2nc(-c3ccc4oc5ccccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4oc5ncccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4[nH]ccc4c3)ccc2c1 +c1cnc2nc(-c3cccc4c3oc3ncccc34)ccc2c1 +c1cnc2nc(-c3cccc4c3sc3ncccc34)ccc2c1 +c1cnc2nc(-c3cccc4c5ccccc5c5[nH]cnc5c34)ccc2c1 +c1cnc2nc(-c3cccc4cnc5ccccc5c34)ccc2c1 +c1cnc2nc(-c3cccc4oc5ncccc5c34)ccc2c1 +c1cnc2nc(-c3cccc4ocnc34)ccc2c1 +c1cnc2nc(-c3cc[nH]n3)cnc2n1 +c1cnc2nc(-c3cncc4[nH]c5ccccc5c34)ccc2c1 +c1cnc2nc(-c3c[nH]c4nc5occc5nc34)cnc2n1 +c1cnc2nc(-n3c4ccccc4c4c5ccccc5[nH]c43)ccc2c1 +c1cnc2nc(-n3c4ccccc4c4ccncc43)ccc2c1 +c1cnc2ncc(-c3c4ccoc4cc4ccoc34)cc2c1 +c1cnc2ncc(-c3cc4nc5cc[nH]c5nc4o3)cc2c1 +c1cnc2ncc(-c3cc4[nH]c5ccccc5c4cn3)cc2c1 +c1cnc2ncc(-c3ccc4c(c3)[nH]c3cnccc34)cc2c1 +c1cnc2ncc(-c3ccc4c(n3)sc3ccccc34)cc2c1 +c1cnc2ncc(-c3ccc4[nH]c5ccncc5c4c3)cc2c1 +c1cnc2ncc(-c3ccc4[nH]c5cnccc5c4c3)cc2c1 +c1cnc2ncc(-c3cccc4c3cnc3ccccc34)cc2c1 +c1cnc2ncc(-c3cccc4c3[nH]c3cnccc34)cc2c1 +c1cnc2ncc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)cc2c1 +c1cnc2ncc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cc2c1 +c1cnc2ncc(-c3cccc4scnc34)cc2c1 +c1cnc2ncc(-c3cc[nH]n3)cc2c1 +c1cnc2ncc(-c3cncc4c3[nH]c3ccccc34)cc2c1 +c1cnc2ncc(-c3coc4nc5[nH]ccc5nc34)cc2c1 +c1cnc2ncc(-c3nc4ccccc4s3)cc2c1 +c1cnc2ncc(-c3nccc4[nH]c5ccccc5c34)cc2c1 +c1cnc2ncc(-n3cnc4c5ccccc5c5ccccc5c43)cc2c1 +c1cnc2nccc(-c3cc4[nH]c5ccncc5c4cn3)c2c1 +c1cnc2nccc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)c2c1 +c1cnc2nccc(-c3ccc4c5ccccc5c5nccnc5c4c3)c2c1 +c1cnc2nccc(-c3ccc4ccsc4c3)c2c1 +c1cnc2nccc(-c3ccc4occc4c3)c2c1 +c1cnc2nccc(-c3ccc4sc5ncccc5c4c3)c2c1 +c1cnc2nccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)c2c1 +c1cnc2nccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c2c1 +c1cnc2nccc(-n3c4ccccc4c4ccncc43)c2c1 +c1cnc2nccc(-n3ccc4cc5ccoc5cc43)c2c1 +c1cnc2nccc(-n3cnc4c5ccccc5c5ccccc5c43)c2c1 +c1cnc2oc3c(-c4c5[nH]cnc5cc5nc[nH]c45)cccc3c2c1 +c1cnc2oc3c(-c4ccc5ncoc5c4)cccc3c2c1 +c1cnc2oc3c(-c4cnc5nccnc5n4)cccc3c2c1 +c1cnc2oc3c(-c4cncc5c4[nH]c4ccncc45)cccc3c2c1 +c1cnc2oc3c(-c4ncon4)cccc3c2c1 +c1cnc2oc3cc(-c4c5[nH]cnc5cc5nc[nH]c45)ccc3c2c1 +c1cnc2oc3cc(-c4cc5nc6cc[nH]c6nc5o4)ccc3c2c1 +c1cnc2oc3cc(-c4ccc5ncoc5c4)ccc3c2c1 +c1cnc2oc3cc(-c4cccc5c4[nH]c4cnccc45)ccc3c2c1 +c1cnc2oc3cc(-c4c[nH]c5ccncc45)ccc3c2c1 +c1cnc2oc3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c2c1 +c1cnc2oc3ccc(-c4c5[nH]cnc5nc5nc[nH]c45)cc3c2c1 +c1cnc2oc3ccc(-c4cc5cnccc5[nH]4)cc3c2c1 +c1cnc2oc3ccc(-c4cc5nc6cc[nH]c6nc5o4)cc3c2c1 +c1cnc2oc3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c2c1 +c1cnc2oc3ccc(-c4ccc5c(c4)[nH]c4cnccc45)cc3c2c1 +c1cnc2oc3ccc(-c4ccc5sccc5c4)cc3c2c1 +c1cnc2oc3ccc(-c4c[nH]c5ccncc45)cc3c2c1 +c1cnc2oc3ccc(-c4nc5cc6nc[nH]c6cc5[nH]4)cc3c2c1 +c1cnc2sc3c(-c4c5[nH]cnc5nc5nc[nH]c45)cccc3c2c1 +c1cnc2sc3c(-c4cncs4)cccc3c2c1 +c1cnc2sc3c(-c4nc5cc6nc[nH]c6cc5[nH]4)cccc3c2c1 +c1cnc2sc3c(-c4nc5nc6ocnc6nc5o4)cccc3c2c1 +c1cnc2sc3c(-c4nccs4)cccc3c2c1 +c1cnc2sc3c(-c4ncon4)cccc3c2c1 +c1cnc2sc3c(-n4cnc5nc6nc[nH]c6cc54)cccc3c2c1 +c1cnc2sc3cc(-c4c5nc[nH]c5cc5[nH]cnc45)ccc3c2c1 +c1cnc2sc3cc(-c4cc5cnccc5[nH]4)ccc3c2c1 +c1cnc2sc3cc(-c4coc5cc6ccoc6cc45)ccc3c2c1 +c1cnc2sc3cc(-c4c[nH]c5nc6occc6nc45)ccc3c2c1 +c1cnc2sc3cc(-c4ncno4)ccc3c2c1 +c1cnc2sc3cc(-n4c5ccccc5c5ccncc54)ccc3c2c1 +c1cnc2sc3ccc(-c4c5nc[nH]c5cc5[nH]cnc45)cc3c2c1 +c1cnc2sc3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c2c1 +c1cnc2sc3ccc(-c4ccc(-c5cnccn5)cc4)cc3c2c1 +c1cnc2sc3ccc(-c4nc5nc6ocnc6nc5o4)cc3c2c1 +c1cnc2sc3ccc(-c4nccc5[nH]c6ccncc6c45)cc3c2c1 +c1cnc2sc3ccc(-n4cnc5nc6nc[nH]c6cc54)cc3c2c1 +c1cnc2sc3nc(-c4c5[nH]cnc5nc5nc[nH]c45)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5nn[nH]c5c4)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5ocnc5c4)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5[nH]nnc5c4)ccc3c2c1 +c1cnc2sc3nc(-c4cnoc4)ccc3c2c1 +c1cnc2sc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)ccc3c2c1 +c1cnc2sc3nc(-c4nccc5[nH]ccc45)ccc3c2c1 +c1cnc2sc3ncc(-c4cc5nc6ccoc6nc5[nH]4)cc3c2c1 +c1cnc2sc3ncc(-c4cscn4)cc3c2c1 +c1cnc2sc3ncc(-c4c[nH]c5nc6occc6nc45)cc3c2c1 +c1cnc2sc3ncc(-n4c5ccccc5c5ccncc54)cc3c2c1 +c1cnc2sc3ncc(-n4c5ccncc5c5cnccc54)cc3c2c1 +c1cnc2sc3ncc(-n4cnc5nc6nc[nH]c6nc54)cc3c2c1 +c1cnc2sc3nccc(-c4cc5cnccc5[nH]4)c3c2c1 +c1cnc2sc3nccc(-c4ccc5ncoc5c4)c3c2c1 +c1cnc2sc3nccc(-c4ccc5ocnc5c4)c3c2c1 +c1cnc2sc3nccc(-c4ccon4)c3c2c1 +c1cnc2sc3nccc(-c4cnc5nccnc5n4)c3c2c1 +c1cnc2sc3nccc(-c4nc5nc6nc[nH]c6cc5[nH]4)c3c2c1 +c1cnc2sc3nccc(-n4c5ccccc5c5ccncc54)c3c2c1 +c1cnc2[nH]c3c(-c4c5cc[nH]c5cc5occc45)cccc3c2c1 +c1cnc2[nH]c3c(-c4cc5cc6ccoc6cc5[nH]4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5c(c4)c4ccccc4c4nccnc54)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5c6ccccc6c6nccnc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5oc6ncccc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5[nH]c6ccncc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4c[nH]c5nc6occc6nc45)cccc3c2c1 +c1cnc2[nH]c3c(-c4nc5cc6ocnc6cc5o4)cccc3c2c1 +c1cnc2[nH]c3c(-c4nc5nc6nc[nH]c6nc5[nH]4)cccc3c2c1 +c1cnc2[nH]c3c(-c4nccc5[nH]c6ccncc6c45)cccc3c2c1 +c1cnc2[nH]c3cc(-c4c5ncoc5cc5ncoc45)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5c(n4)sc4ncccc45)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5c6ccccc6c6nc[nH]c6c5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5occc5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5[nH]c6ccncc6c5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4nc5c6ccccc6c6ccccc6c5[nH]4)ccc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5c(c4)oc4ncccc45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5c6ccccc6c6nccnc6c5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5ccoc5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5oc6ncccc6c5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4cccc5c6ccccc6c6[nH]cnc6c45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccnc5sc6ncccc6c45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccnnc4)cc3c2c1 +c1cnc2[nH]c3ccc(-n4c5ccccc5c5cnccc54)cc3c2c1 +c1cnc2[nH]c3ccc(-n4cnc5nc6nc[nH]c6nc54)cc3c2c1 +c1cnn(-c2ccc(-c3cnccn3)cc2)c1 +c1cnn(-c2ccc3[nH]nnc3c2)c1 +c1cnn(-c2cscn2)c1 +c1cnn(-c2c[nH]c3nc4occc4nc23)c1 +c1cnn(-n2cnc3nc4nc[nH]c4nc32)c1 +c1cnnc(-c2cc3cccnc3c3ncccc23)c1 +c1cnnc(-c2ccc(-c3cnccn3)cc2)c1 +c1cnnc(-c2ccc3c(c2)[nH]c2ncccc23)c1 +c1cnnc(-c2ccc3c(cnc4ccccc43)c2)c1 +c1cnnc(-c2ccc3sc4ccccc4c3c2)c1 +c1cnnc(-c2ccc3[nH]c4cnccc4c3c2)c1 +c1cnnc(-c2cccc3cnc4ccccc4c23)c1 +c1cnnc(-c2ccnc3c2ccc2cccnc23)c1 +c1cnnc(-c2ccnc3cccnc23)c1 +c1cnnc(-c2cnc3[nH]c4ccccc4c3c2)c1 +c1cnnc(-c2cncc3cc[nH]c23)c1 +c1cnnc(-c2cnoc2)c1 +c1cnnc(-c2cscn2)c1 +c1cnnc(-c2nccs2)c1 +c1cnnc(-n2nnc3ccccc32)c1 +c1csc(-c2c3ncsc3cc3ncsc23)n1 +c1csc(-c2cc3nc4ccoc4nc3[nH]2)n1 +c1csc(-c2ccc3ccsc3c2)n1 +c1csc(-c2cn[nH]c2)n1 +c1csc(-c2coc3cc4[nH]ccc4cc23)n1 +c1csc(-c2c[nH]c3nc4occc4nc23)n1 +c1nc(-c2ccc3sccc3c2)cs1 +c1nc(-n2ccc3nc4ccoc4nc32)no1 +c1nc2c(-c3c4ncsc4cc4ncsc34)c3nc[nH]c3cc2[nH]1 +c1nc2c(-c3ccc4c5c3CCCN5CCC4)c3nc[nH]c3cc2[nH]1 +c1nc2c(-c3ccc4ncsc4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4nn[nH]c4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4scnc4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4[nH]nnc4c3)c3scnc3cc2s1 +c1nc2c(-c3nc4nc5nc[nH]c5nc4[nH]3)c3nc[nH]c3cc2[nH]1 +c1nc2c(-n3ccc4nc5ccoc5nc43)c3nc[nH]c3cc2[nH]1 +c1nc2cc(-c3ccc4ncsc4c3)ccc2o1 +c1nc2cc(-c3ccc4nn[nH]c4c3)ccc2o1 +c1nc2cc(-c3ccc4ocnc4c3)ccc2o1 +c1nc2cc(-c3cnoc3)ccc2s1 +c1nc2cc(-c3cscn3)ccc2o1 +c1nc2cc3nc(-c4cc5nc6ccoc6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2cc3nc(-c4ccc5ccsc5c4)[nH]c3cc2[nH]1 +c1nc2cc3nc(-c4ccc5scnc5c4)oc3nc2o1 +c1nc2cc3nc(-c4ccc5[nH]nnc5c4)oc3nc2o1 +c1nc2cc3nc(-c4c[nH]c5nc6occc6nc45)[nH]c3cc2[nH]1 +c1nc2cc3ncn(-c4c5cc[nH]c5cc5occc45)c3cc2[nH]1 +c1nc2cc3ncn(-c4cc5c6c(c4)CCCN6CCC5)c3cc2[nH]1 +c1nc2cc3ncn(-c4ccc5ccsc5c4)c3cc2[nH]1 +c1nc2cc3ncn(-c4ccc5scnc5c4)c3cc2[nH]1 +c1nc2cc3oc(-c4ccc5nn[nH]c5c4)nc3cc2o1 +c1nc2cc3oc(-c4cnoc4)nc3cc2o1 +c1nc2ccc(-c3c4ncoc4nc4ocnc34)cc2o1 +c1nc2ccc(-c3c4ncsc4cc4ncsc34)cc2o1 +c1nc2ccc(-c3cnoc3)cc2o1 +c1nc2ccc(-c3c[nH]c4nc5occc5nc34)cc2o1 +c1nc2ccc(-c3nc4nc5ocnc5nc4o3)cc2o1 +c1nc2nc3nc(-c4c5ncsc5cc5ncsc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4c5[nH]ccc5cc5ccoc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4cc5nc6ccoc6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4ccc5scnc5c4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4c[nH]c5nc6occc6nc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5cc6ncoc6nc5o4)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5nc6ocnc6nc5o4)[nH]c3nc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]ccc5cc5ccoc45)c3cc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]ccc5cc5ccoc45)c3nc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]cnc5nc5nc[nH]c45)c3nc2[nH]1 +c1nc2nc3ncn(-c4cc5nc6ccoc6nc5[nH]4)c3cc2[nH]1 +c1nc2nc3ncn(-c4ccc(-c5cc6c7c(c5)CCCN7CCC6)cc4)c3nc2[nH]1 +c1nc2nc3ncn(-c4ccc5ncoc5c4)c3nc2[nH]1 +c1nc2nc3ncn(-c4ncon4)c3nc2[nH]1 +c1nc2nc3nc[nH]c3c(-c3c4ncoc4cc4ncoc34)c2[nH]1 +c1nc2nc3nc[nH]c3c(-c3ccc4ocnc4c3)c2[nH]1 +c1nc2nc3nc[nH]c3c(-c3c[nH]c4cc5occc5cc34)c2[nH]1 +c1nc2nc3oc(-c4c5ncsc5cc5ncsc45)nc3nc2o1 +c1nc2nc3oc(-c4ccc(-c5cc6c7c(c5)CCCN7CCC6)cc4)nc3nc2o1 +c1nc2nc3oc(-c4ccc5scnc5c4)nc3nc2o1 +c1ncc(-c2ccc3[nH]nnc3c2)s1 +c1noc(-c2c3ncsc3cc3ncsc23)n1 +c1noc(-c2cc3c4c(c2)CCCN4CCC3)n1 +c1noc(-c2ccc3ocnc3c2)n1 +c1noc(-c2coc3cc4ccoc4cc23)n1 +c1noc(-c2nc3cc4ocnc4cc3o2)n1 +c1noc(-c2nc3nc4nc[nH]c4nc3[nH]2)n1 +c1nocc1-c1ccc2c3c1CCCN3CCC2 +CC(=O)c1ccc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +CC(=O)c1ccc(-c2cc(C)c3[nH]c4c(C)cccc4c3c2)cc1 +CC(=O)c1ccc(-c2cc(N(C)C)c3ccccc3c2)cc1 +CC(=O)c1ccc(-c2cc3c4c(c2)CCCN4CCC3)cc1 +CC(=O)c1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)cc1 +CC(=O)c1ccc(-c2cc3cc4cc[nH]c4cc3o2)cc1 +CC(=O)c1ccc(-c2cc3ccccc3[nH]2)cc1 +CC(=O)c1ccc(cc1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +CC(=O)c1ccc(cc1)c1cc2c(Sc3c(cccc3)N2)cc1 +CC(=O)c1ccc(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +CC(=O)c1ccc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)Oc2ccccc2N3C)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cc1 +CC(=O)c1ccc(-c2ccc3c(n2)sc2ccccc23)cc1 +CC(=O)c1ccc(-c2ccc3c4c(C)c(C)c(C)cc4n(C)c3c2)cc1 +CC(=O)c1ccc(-c2ccc3oc4ncccc4c3c2)cc1 +CC(=O)c1ccc(-c2ccc3[nH]c4ccc5c6ccccc6[nH]c5c4c3c2)cc1 +CC(=O)c1ccc(-c2cccc(N)c2)cc1 +CC(=O)c1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)cc1 +CC(=O)c1ccc(-c2cccc3c2-c2ccccc2C3(C)C)cc1 +CC(=O)c1ccc(cc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +CC(=O)c1ccc(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +CC(=O)c1ccc(-c2cccc3c2ncc2ccccc23)cc1 +CC(=O)c1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +CC(=O)c1ccc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +CC(=O)c1ccc(-c2cccc3oc4ccccc4c23)cc1 +CC(=O)c1ccc(-c2cccc3oc4ncccc4c23)cc1 +CC(=O)c1ccc(-c2cccc3occc23)cc1 +CC(=O)c1ccc(-c2cccc3scnc23)cc1 +CC(=O)c1ccc(-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)cc1 +CC(=O)c1ccc(-c2cccc3[nH]c4ccncc4c23)cc1 +CC(=O)c1ccc(-c2cc[nH]n2)cc1 +CC(=O)c1ccc(-c2coc3nc4[nH]ccc4nc23)cc1 +CC(=O)c1ccc(-c2nc3cc4scnc4cc3s2)cc1 +CC(=O)c1ccc(-c2nc3ccccc3o2)cc1 +CC(=O)c1ccc(-c2nccc3c2[nH]c2ccccc23)cc1 +CC(=O)c1ccc(-n2c3ccccc3c(=O)c3ccccc32)cc1 +CC(=O)c1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)cc1 +CC(=O)c1ccc(-n2c3ccccc3c3ccncc32)cc1 +CC(=O)c1ccc(-n2cnc3c4ccccc4c4ccccc4c32)cc1 +CC(=O)c1ccc(-n2nnc3ccccc32)cc1 +CC(=O)c1cccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +CC(=O)c1cccc(-c2c(C)c(C)c(C)c3c4ccccc4n(C)c23)c1 +CC(=O)c1cccc(c1)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +CC(=O)c1cccc(c1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +CC(=O)c1cccc(-c2cc3ccccc3cc2N(C)C)c1 +CC(=O)c1cccc(-c2cc3ccccc3o2)c1 +CC(=O)c1cccc(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +CC(=O)c1cccc(c1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +CC(=O)c1cccc(-c2ccc3c(n2)sc2ccccc23)c1 +CC(=O)c1cccc(c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +CC(=O)c1cccc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)c1 +CC(=O)c1cccc(-c2ccc3cc(N(C)C)ccc3c2)c1 +CC(=O)c1cccc(-c2ccc3occc3c2)c1 +CC(=O)c1cccc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c1 +CC(=O)c1cccc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c1 +CC(=O)c1cccc(c1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +CC(=O)c1cccc(c1)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +CC(=O)c1cccc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +CC(=O)c1cccc(-c2cccc3c2oc2ncccc23)c1 +CC(=O)c1cccc(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)c1 +CC(=O)c1cccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c1 +CC(=O)c1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +CC(=O)c1cccc(-c2cccc3ocnc23)c1 +CC(=O)c1cccc(-c2cccc3scnc23)c1 +CC(=O)c1cccc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c1 +CC(=O)c1cccc(-c2ccnc3sc4ncccc4c23)c1 +CC(=O)c1cccc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +CC(=O)c1cccc(-c2coc3cc4ccoc4cc23)c1 +CC(=O)c1cccc(-c2c[nH]c3ccccc23)c1 +CC(=O)c1ccccc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +CC(=O)c1ccccc1-c1c2ncsc2cc2ncsc12 +CC(=O)c1ccccc1-c1cc(C)c2[nH]c3c(C)cccc3c2c1 +CC(=O)c1ccccc1-c1cc2cc3cc[nH]c3cc2o1 +CC(=O)c1ccccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +CC(=O)c1ccccc1c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +CC(=O)c1ccccc1c1ccc2CCc3c(cccc3)Nc2c1 +CC(=O)c1ccccc1-c1ccc2c(c1)c1ccccc1c1nc[nH]c21 +CC(=O)c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12 +CC(=O)c1ccccc1-c1ccc2cc(N(C)C)ccc2c1 +CC(=O)c1ccccc1-c1ccc2oc3ccccc3c2c1 +CC(=O)c1ccccc1-c1ccc2oc3ncccc3c2c1 +CC(=O)c1ccccc1-c1ccc2[nH]c3ccccc3c(=O)c2c1 +CC(=O)c1ccccc1-c1ccc2[nH]c3cnccc3c2c1 +CC(=O)c1ccccc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +CC(=O)c1ccccc1-c1cccc2c1oc1ncccc12 +CC(=O)c1ccccc1-c1cccc2c1sc1ncccc12 +CC(=O)c1ccccc1-c1cccc2c3c(C)c(C)c(C)cc3n(C)c12 +CC(=O)c1ccccc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +CC(=O)c1ccccc1-c1cccc2cc(N(C)C)ccc12 +CC(=O)c1ccccc1-c1cccc2oc3ncccc3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3ccc4c5ccccc5[nH]c4c3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3cnccc3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3[nH]c4ccccc4c3c12 +CC(=O)c1ccccc1-c1cccnn1 +CC(=O)c1ccccc1-c1cncc2c1[nH]c1ccccc12 +CC(=O)c1ccccc1-c1cncc2c1[nH]c1ccncc12 +CC(=O)c1ccccc1-n1c2ccccc2c2ccncc21 +CC(=O)c1ccccc1-n1c2ccccc2c2cnccc21 +CC(=O)c1ccccc1-n1nnc2ccccc21 +Cc1(-c2c3ccoc3cc3ccoc23)-c2ccccc2-c2ccccc2-1 +N#Cc1c(c(C#N)cc(c1)C1(C)c2c(cccc2)Nc2c1cccc2)C#N +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2C2(C)c3c(cccc3)Nc3c2cccc3)ccccc1 +c12c(sc(c1)C1(C)c3c(cccc3)Nc3c1cccc3)cccc2 +Cc1(-c2cc3ccccc3[nH]2)-c2ccccc2-c2ccccc2-1 +N#Cc1ccc(c(C#N)c1)C1(C)c2c(cccc2)Nc2c1cccc2 +O=c1c2c(cc(cc2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +CC1(c2c(-c3c1cccc3)cccc2)c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1c2c(C(=O)N1)ccc(c2)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2ccc3c4c2CCCN4CCC3)-c2ccccc2-c2ccccc2-1 +c12c(b3c4c(oc5c3c(o1)c(cc5)C1(C)c3c(cccc3)Nc3c1cccc3)cccc4)cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)C1(C)c2c(cccc2)Nc2c1cccc2 +c12c(nn[nH]2)ccc(c1)C1(C)c2c(cccc2)Nc2c1cccc2 +n1c2c(oc1)ccc(c2)C1(C)c2c(cccc2)Nc2c1cccc2 +O=c1c2c(ccc(c2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +Cc1(-c2ccc3[nH]ccc(=O)c3c2)-c2ccccc2-c2ccccc2-1 +c12c(nn[nH]2)cc(cc1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c(=O)c4ccccc4[nH]c23)-c2ccccc2-c2ccccc2-1 +O=C1c2c(C(=O)N1)cccc2C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cccc3c2sc2ncccc23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c2[nH]c2cnccc23)-c2ccccc2-c2ccccc2-1 +c12c(c(ccc2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]c2ncccc12 +Cc1(-c2cccc3c4ccccc4c4nc[nH]c4c23)-c2ccccc2-c2ccccc2-1 +c12c(scc1)c(ccc2)C1(C)c2c(cccc2)Nc2c1cccc2 +c12c(cccc2C2(C)c3c(cccc3)Nc3c2cccc3)cnc2c1cccc2 +Cc1(-c2cccc3nn[nH]c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3oc4ncccc4c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3occc23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccnn2)-c2ccccc2-c2ccccc2-1 +c1(c2ncc(nc2)C2(C)c3c(cccc3)Nc3c2cccc3)ccccc1 +n1c2c(ccc1)ccc1c2ncc(c1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cnc3c4ccccc4c4ccccc4c3n2)-c2ccccc2-c2ccccc2-1 +c12c(c3c(c(cnc3)C3(C)c4c(cccc4)Nc4c3cccc4)[nH]2)cncc1 +Cc1(-c2c[nH]c3ccccc23)-c2ccccc2-c2ccccc2-1 +n1c2nc3nc(C4(C)c5c(cccc5)Nc5c4cccc5)[nH]c3nc2[nH]c1 +n1c2nc3oc(nc3nc2oc1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2nccc3c2[nH]c2ccccc23)-c2ccccc2-c2ccccc2-1 +c12c(ccnc2C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +n1ccsc1C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-n2c3ccccc3c3cnccc32)-c2ccccc2-c2ccccc2-1 +O=C1c2c(C(=O)C(=C1)c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +O=c1c2c(cc(cc2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +O=C1c2c(C(=O)C=C1)ccc(c2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2c1ccnc2 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2ncccc12 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +n1c2c(oc1)cc(cc2)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(ccc(c2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]c2c1ccnc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(sc3c1cccc3c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(oc1)c(ccc2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)cccc1c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(nn[nH]2)c(ccc1)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(c2ncccc2c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ncccc1 +n1c2c(nccc2)c(cc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(ncc(c2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccc1 +c12c(c(cnc2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +c12c(c(cnc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]cc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1cc(sc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c(csc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=c1c2c(cccc2)[nH]cc1c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(ccnc2)[nH]cc1c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(c3c(n1c1cc4c(cc1)Nc1c5c6c(n(c7ccccc7)c5ccc1C4(C)C)cccc6)ccnc3)cncc2 +O=C1C=CC(=O)N1c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +n1c2c(c(c3c(nc[nH]3)c2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c1 +O=c1c2c(cc(cc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)cccc2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(cc(cc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)cnc2c1cccc2 +c12c(scc1)cc(cc2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +O=c1c2c(ccc(c2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(c(ccc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2ncccc12 +c12c(cccc2)cnc2c1c(ccc2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(cccc2c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2c1ccnc2 +c12c(cccc2c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2ncccc12 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +n1occ(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(n(c3c1ccnc3)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)cccc2 +c12c(n(cc1)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)ccnc2 +n1c2nc3nc[nH]c3cc2n(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +O=C1C=C(C(=O)N1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ccccc1 +c1(c2ncc(cc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ncccc1 +c1(c2nccnc2)ccc(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(cc(cc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12nccnc1ccc(c2)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(c(ccc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +c12c(sc3c1c(ccc3)c1c3c(ccc1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +n1c2ncccc2c(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(ccc1)ccc1c2ncc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2ncc(nc2ncc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c(csc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(nc3c(nc(o3)c3c4c(ccc3)Nc3c(C4(C)C)cc4n(c5ccccc5)c5c(c4c3)cccc5)c2)oc1 +c1(C#N)cnc(nc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1cccc(C#N)c1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(c(c3c(nc[nH]3)c2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c1 +c12nc3c(oc(c3)c3ccc4c(c3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)nc1[nH]cc2 +N#Cc1c(c(C#N)c(cc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3)C#N +N#Cc1ccc(c(C#N)c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +c12c(cc(cc2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +c12c(cccc2)[nH]c2nc(ccc12)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2nc(ccc2ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(ccc(c2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)ccc(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(nn[nH]2)cc(cc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1c(C#N)c(ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +c12c(nn[nH]2)c(ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1ccccc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2ncccc2c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ncccc1 +c1(c2nccc(c2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(nccc2)c(cc1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2nc(cnc2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ccccc1 +c12c(c(cnc2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +n1cc(sc1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1cc(sc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(cccc2)c(nc2c1cccc2)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2nc3nc(c4ccc5c(c4)Nc4c6c7c(n(c8ccccc8)c6ccc4C5(C)C)cccc7)[nH]c3cc2[nH]c1 +n1c2nc3nc(c4ccc5c(c4)Nc4c(C5(C)C)cc5n(c6ccccc6)c6c(c5c4)cccc6)[nH]c3nc2[nH]c1 +c12c(ccnc2c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +n1ccsc1c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1cnoc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)C(=C1)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(nc3c(nco3)c2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)oc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +N#Cc1c(c(C#N)cc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4)C#N +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1c3c(ccc1)Nc1c5c6c(n(c7ccccc7)c5ccc1C3(C)C)cccc6)cccc4)cccc2 +c12c(cc(nc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +N#Cc1ccc(cc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cc(cc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]c2ncccc12 +n1c2c(nc(cc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccc1 +O=C(c1cccc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(sc3c1cccc3c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +c12c(scc1)c(ccc2)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)cccc1c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=c1c2c(cccc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +N#Cc1ccccc1c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cccc2)[nH]c2nccc(c12)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1occ(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12nc3c(occ3c3c4c(ccc3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)nc1[nH]cc2 +c12c(scc1c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c(csc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12nc3c(occ3)nc1[nH]cc2c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(nc3c(nc(o3)c3c4c(ccc3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)c2)oc1 +n1c2c(cc3c(nc(c4c5c(ccc4)Nc4c6c7c(n(c8ccccc8)c6ccc4C5(C)C)cccc7)[nH]3)c2)[nH]c1 +c1(C#N)cnc(nc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2nccnc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +c12c(n(c3ncccc13)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)cc2)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ccccc1 +O=c1c2c(cccc2)[nH]c(c1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +N#Cc1c(c(C#N)c(cc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1)C#N +N#Cc1ccc(cc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(scc1)cc(cc2)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(nn[nH]2)ccc(c1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(sc3c1cc(cc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +O=c1c2c(ccc(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c12c(cccc2c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)cnc2c1cccc2 +c12c(nn[nH]2)cccc1c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(sc3c1c(ccc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +c1(c2nccnc2)ccccc1c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c1(c2nccc(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ncccc1 +c1(c2nc(cnc2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ccccc1 +c12c(c3c(c(cnc3)c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)[nH]2)cncc1 +c12nc3c(occ3c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)nc1[nH]cc2 +n1c2nc3oc(nc3nc2oc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(n(cc1)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)ccnc2 +CC1(c2c(-c3c1cccc3)cccc2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +O=C1c2c(C(=O)C(=C1)N1c3c(C(c4c1cccc4)(C)C)cc1n(c4ccccc4)c4c(c1c3)cccc4)cccc2 +O=C1c2c(C(=O)C(=C1)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +O=C1c2c(C(=O)N1N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +O=C1C=CC(=O)N1N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +O=C1C=CC(=O)N1N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2c(nc3c(nco3)c2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)oc1 +n1c2c(cc3c(nc[nH]3)c2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)ccccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)N2c3c(C(C)(c4c2cccc4)C)cccc3)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)N1c3c(C(c5c1cccc5)(C)C)cc1n(c5ccccc5)c5c(c1c3)cccc5)cccc4)cccc2 +n1c2c(ccc1)cc(c1c2nccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2nccnc2)ccc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +N#Cc1c(C#N)cc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +N#Cc1c(c(C#N)c(cc1)N1c2c(C(C)(c3c1cccc3)C)cccc2)C#N +N#Cc1ccc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +O=c1c2c(cc(cc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(cccc2)cnc2c1ccc(c2)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(cccc2)cnc2c1ccc(c2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +c12c(sc3c1ccc(c3)N1c3c(C(c4c1cccc4)(C)C)cc1n(c4ccccc4)c4c(c1c3)cccc4)cccc2 +c12c(sc3c1ccc(c3)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +c12c(cc(cc2)N2c3c(C(C)(c4c2cccc4)C)cccc3)cnc2c1cccc2 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)N1c3c5c6c(n(c7ccccc7)c5ccc3C(c3c1cccc3)(C)C)cccc6)cccc4)cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cc(cc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cc(cc2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12nccnc1ccc(c2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(nn[nH]2)ccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(sc3c1cc(cc3)N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +c12c(ccc(c2)N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2c1ccnc2 +c12c(ccc(c2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]c2ncccc12 +c1(c2ncccc2)nc(ccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2ncccc2)nc(ccc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +N#Cc1cccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +O=c1c2c(c(ccc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(c(ccc2)N2c3c(C(C)(c4c2cccc4)C)cccc3)cnc2c1cccc2 +c12c(cccc2N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)cnc2c1cccc2 +c12nccnc1c(ccc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cccc2N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(cccc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2c1ccnc2 +c12c(cccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c2c1ccnc2 +c12c(cccc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2ncccc12 +c12c(cccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c2ncccc12 +O=c1c2c(cccc2N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(nn[nH]2)c(ccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2nccnc2)ccccc1N1c2c(C(C)(c3c1cccc3)C)cccc2 +N#Cc1ccccc1N1c2c(C(C)(c3c1cccc3)C)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2ncccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)ncccc1 +c1(c2nccc(c2)N2c3c(C(C)(c4c2cccc4)C)cccc3)ncccc1 +n1occc1N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +n1c2c(ccc1)ccc1c2ncc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +n1c2c(ccc1)ccc1c2ncc(c1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2ncc(cc2ccc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2ncc(nc2ncc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c1(c2nc(cnc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)ccccc1 +n1c(csc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(cccc2)[nH]c2c1ccnc2N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +n1cnoc1N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +O=c1c2c(n(cc1)N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +c12nc3c(occ3)nc1n(cc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +n1c2nc3nc[nH]c3nc2n(c1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +Fc1c(c(c(c(F)c1c1c2c(C(C)(c3c(cccc3)N2)C)ccc1)F)F)F +n1c2c(nc3c(nco3)c2c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)oc1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c1 +N#Cc1cc(cc(C#N)c1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)c2 +c12c(ccnc2)[nH]c(c1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(c3c(cc(nc3)c3c4c(C(C)(c5c(cccc5)N4)C)ccc3)[nH]2)cncc1 +c1(c2ncc(cc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ncccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(cc(cc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c2ncccc12 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(C(C)(c5c(cccc5)N3)C)ccc1)cccc4)cccc2 +c12c(scc1)ccc(c2)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(ccc(c2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c2ncccc12 +c12c(sc3c1c(ccc3)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +n1c2c(nccc2)c(cc1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c1(c2ncc(nc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ccccc1 +n1ccsc1c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(n(c3ncccc13)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3c4c(c5c6c(n(c7ccccc7)c5c3)cccc6)Nc3c(C4(C)C)cccc3)cc2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)c2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +N#Cc1ccc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(cc(cc2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)cnc2c1cccc2 +n1c2c(nc(cc2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ccc1 +c12c(scc1)ccc(c2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(nn[nH]2)cc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)cccc2 +O=c1c2c(cccc2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)[nH]cc1 +c1(c2nccc(c2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ncccc1 +n1c2c(nccc2)c(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1oc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12ncc(nc1cccc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c2ncc(cc2ccc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c(csc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c2nc3oc(nc3nc2oc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c1(c2nccnc2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ccccc1 +n1ccsc1c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +O=c1c2c(n(cc1)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)cccc2 +c12nc3c(occ3)nc1n(cc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +N#Cc1cc(C#N)cc(C#N)c1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3)F)F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)ccccc1 +c1(c2ncc(cc2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)ncccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3n(c5ccccc5)c5c(c3c3c(C(c6c(cccc6)N3)(C)C)c1)cccc5)cccc4)cccc2 +c12c(ccc(c2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)[nH]c2ncccc12 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(nn[nH]2)cccc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +n1c2ncccc2c(cc1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(ccnc2)[nH]cc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +n1ccsc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +CC1(c2c(-c3c1cccc3)cccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +O=C1c2c(C(=O)N1c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +O=c1c2c(cc(cc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)[nH]cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(c(ccc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)cnc2c1cccc2 +c12c(scc1)c(ccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(cccc2)cnc2c1c(ccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +n1c2c(oc1)cccc2c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(sc3c1c(ccc3)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +c12c(nn[nH]2)c(ccc1)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +n1c2c(ncc(c2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)ccc1 +c1(c2nc(cnc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)ccccc1 +c12c(occ1)cc1c(occ1c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)c2 +c12c(n(cc1)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)ccnc2 +CC1(c2c(-c3c1cccc3)cccc2)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +O=C1C=CC(=O)N1c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)[nH]c1 +N#Cc1c(c(C#N)c(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1)C#N +c12c(cccc2)cnc2c1ccc(c2)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(n(c5ccccc5)c5c3c3c(C(c6c(cccc6)N3)(C)C)cc5)ccc1)cccc4)cccc2 +n1c2c(nc(cc2)c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(oc1)cccc2c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(scc1)cccc2c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(nccc2)c(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1oc(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(ccc1)ccc1c2ncc(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(ncc(c2)c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)ccc1 +n1c2ncc(cc2ccc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1cc(sc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(occ1)cc1c(occ1c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)c2 +n1c2c(nc3c(nc(o3)c3c4c(n(c5ccccc5)c5c4c4c(C(c6c(cccc6)N4)(C)C)cc5)ccc3)c2)oc1 +c12c(n(c3c1ccnc3)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +n1c2c(n(c1)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(nnn1c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +Fc1c(c(c(c(F)c1c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3)F)F)F +c12c(cccc2)[nH]c2c1cc(nc2)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(occ1)cc1c(oc(c1)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)c2 +c12nc3c(oc(c3)c3ccc4n(c5ccccc5)c5c(c4c3)c3c(C(c4c(cccc4)N3)(C)C)cc5)nc1[nH]cc2 +c12c(cc(nc2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +N#Cc1ccc(c(C#N)c1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(ccc(c2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)cnc2c1cccc2 +c1(c2ncccc2)nc(ccc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(c(ccc2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]c2ncccc12 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1oc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2ncc(nc2ncc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12nc3c(occ3)nc1[nH]cc2c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(cc3c(nc(c4ccc5n(c6ccccc6)c6c(c5c4)c4c(C(c5c(cccc5)N4)(C)C)cc6)[nH]3)c2)[nH]c1 +n1c2nc3oc(nc3nc2oc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(n(c3c1ccnc3)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2nc3nc[nH]c3nc2n(c1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2ncc(cc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +N#Cc1ccc(c(C#N)c1)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +O=C1c2c(C(=O)C=C1)ccc(c2)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2c(nc(cc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccc1 +O=C1c2c(C(=O)N1)cccc2c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(scc1)cccc2c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2nccc(c2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2ncc(nc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccccc1 +c12nc3c(occ3)nc1n(cc2)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=C1c2c(C(=O)N1c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +N#Cc1cc(C#N)cc(C#N)c1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3)F)F)F +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccccc1 +c12c(c3c(cc(nc3)c3c4n(c5ccccc5)c5c(c4ccc3)c3c(C(c4c(cccc4)N3)(C)C)cc5)[nH]2)cncc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(oc1)cc(cc2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(oc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(scc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +O=C(c1ccccc1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3)C(F)(F)F +c1(c2nccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +n1c2c(nc3c(nc(o3)c3c4n(c5ccccc5)c5c(c4ccc3)c3c(C(c4c(cccc4)N3)(C)C)cc5)c2)oc1 +n1c2c(oc1c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c(noc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=c1c2c(n(cc1)c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +N#Cc1c(c(C#N)cc(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1)C#N +c12c(b3c4c(oc5c3c(o1)cc(c5)c1ccc(n3c5c(c6c3ccc3c6Nc6c(C3(C)C)cccc6)cccc5)cc1)cccc4)cccc2 +c12nc3c(oc(c3)c3ccc(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cc3)nc1[nH]cc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1ccc(n3c5c(c6c3ccc3c6Nc6c(C3(C)C)cccc6)cccc5)cc1)cccc4)cccc2 +c12c(ccc(c2)c2ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc2)cnc2c1cccc2 +c1(c2nccnc2)cccc(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(c(ccc2)c2ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +N#Cc1ccccc1c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +n1occ(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(n(c3c1ccnc3)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +c12c(n(cc1)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)ccnc2 +N#Cc1cc(C#N)cc(C#N)c1c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1cc(cc(C#N)c1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cc(cc2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)cnc2c1cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(sc3c1cc(cc3)c1cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +N#Cc1c(C#N)c(ccc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(c(ccc2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)[nH]c2ncccc12 +n1c2c(oc1)c(ccc2)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nccc(c2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)ncccc1 +c12ncc(nc1cccc2)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2ncc(nc2ncc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(ccnc2)[nH]cc1c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1cccc(C#N)c1c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +N#Cc1c(c(C#N)cc(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1)C#N +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3c(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cccc3)cc2)ccccc1 +c12c(c3c(cc(nc3)c3c(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cccc3)[nH]2)cncc1 +N#Cc1ccc(cc1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cc(cc2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)[nH]c2c1ccnc2 +O=C(c1cccc(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1)C(F)(F)F +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +c1(c2nccc(c2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)ncccc1 +c12ncc(nc1cccc2)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(c(cnc2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)[nH]cc1 +n1ccsc1c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(n(c3ncccc13)c1c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +n1c2nc3nc[nH]c3nc2n(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +O=C1c2c(C(=O)N1c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1cc3c(C(C)(c5c(cccc5)N3)C)cc1)cccc4)cccc2 +n1c2c(oc1)cc(cc2)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c12c(ccc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]c2c1ccnc2 +O=c1c2c(ccc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c1(c2nccnc2)cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +N#Cc1cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(c(ccc2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +N#Cc1ccccc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c1(c2ncccc2c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)ncccc1 +n1occc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +n1c2c(ncc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)ccc1 +n1occ(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +n1c(csc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(cccc2)[nH]cc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(cccc2)[nH]c(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1c3c(n(c5ccccc5)c5c3cc3c(C(c6c(cccc6)N3)(C)C)c5)ccc1)cccc4)cccc2 +c12c(occ1)cc1c(oc(c1)c1c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc1)c2 +c12c(cc(nc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]cc1 +N#Cc1ccc(c(C#N)c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(cc(cc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)cnc2c1cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(n(c5ccccc5)c5c3cc3c(C(c6c(cccc6)N3)(C)C)c5)ccc1)cccc4)cccc2 +O=c1c2c(ccc(c2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +N#Cc1cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(c(ccc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]c2c1ccnc2 +n1c2c(oc1)c(ccc2)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c1(c2ncccc2c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)ncccc1 +c12c(cccc2)[nH]c2nccc(c12)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1occc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1occ(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +O=c1c2c(cccc2)[nH]cc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1c2nc3nc(c4c5c(n(c6ccccc6)c6c5cc5c(C(c7c(cccc7)N5)(C)C)c6)ccc4)[nH]c3cc2[nH]c1 +c12c(n(c3ncccc13)c1c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc1)cccc2 +n1c2nc3nc[nH]c3cc2n(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +O=C1c2c(C(=O)C(=C1)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +O=C1c2c(C(=O)N1c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +O=C1C=CC(=O)N1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)cc2)ccccc1 +O=c1c2c(cccc2)[nH]c(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)[nH]c2c1cc(nc2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12nc3c(occ3)nc1[nH]c(c2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +N#Cc1c(C#N)cc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +N#Cc1ccc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)[nH]c2nc(ccc12)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(nc(cc2)c2cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc2)ccc1 +c12c(nn[nH]2)ccc(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)cnc2c1cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(nn[nH]2)cccc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(scc1)cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +O=C(c1ccccc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1)C(F)(F)F +c12ncc(nc1cccc2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2ncc(cc2ccc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12nc3c(occ3c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)nc1[nH]cc2 +O=c1c2c(cccc2)[nH]cc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(ccnc2)[nH]cc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(nc3c(nc(o3)c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)c2)oc1 +n1ccsc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(n(c1)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cc1c(nc[nH]1)c2 +n1c2c(nc3c(nco3)c2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)oc1 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3ccc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)c3)cc2)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c1)c2 +n1c2c(ccc1)cc(c1c2nccc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c1(c2nccnc2)cccc(c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(c(ccc2)c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2ncccc12 +c12c(nn[nH]2)cccc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(cccc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2c1ccnc2 +c12c(cccc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2ncccc12 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(ccnc2)[nH]cc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +n1c2c(nc3c(nc(o3)c3ccc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)c3)c2)oc1 +n1c2nc3oc(nc3nc2oc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +n1c(noc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(n(cc1)c1ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c1)ccnc2 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3)F)F)F +N#Cc1c(c(C#N)cc(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3)C#N +c12c(ccnc2)[nH]c(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +c12c(c3c(cc(nc3)c3c4n(c5ccccc5)c5c(c4ccc3)cc3c(C(c4c(cccc4)N3)(C)C)c5)[nH]2)cncc1 +c12c(cccc2)[nH]c2nc(ccc12)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(oc1)cc(cc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)cc2c(C(c3c(cccc3)N2)(C)C)c4)[nH]cc1 +c12c(cccc2)cnc2c1c(ccc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(oc1)c(ccc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2ncccc2c(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(nc3c(nc(o3)c3c4n(c5ccccc5)c5c(c4ccc3)cc3c(C(c4c(cccc4)N3)(C)C)c5)c2)oc1 +c1(C#N)cnc(nc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2nc3nc[nH]c3nc2n(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +N#Cc1cc(C#N)cc(C#N)c1c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +Fc1c(c(c(c(F)c1c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1)F)F)F +n1c2c(cc3c(nc[nH]3)c2c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c1 +n1c2c(c(c3c(nc[nH]3)c2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c1 +c12c(occ1)cc1c(oc(c1)c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)c2 +c12c(sc(c1)c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +O=c1c2c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]cc1 +c12c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +c12c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)cnc2c1cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)cnc2c1cc(cc2)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c1(c2ncccc2)nc(ccc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)cnc2c1cccc2c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(scc1)c(ccc2)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +n1c2c(nccc2)c(cc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(occ1)cc1c(occ1c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)c2 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3cc(n4c5c(c6c4cc4c(c6)Nc6c(C4(C)C)cccc6)cccc5)ccc3)cc2)ccccc1 +n1c2c(ccc1)cc(c1c2nccc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1ccc(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(ccc(c2)c2cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc2)cnc2c1cccc2 +c1(c2ncccc2)nc(ccc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=C(c1cccc(c1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1)C(F)(F)F +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +n1c2c(ccc1)ccc1c2nccc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2ncccc2c(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=c1c2c(cccc2)[nH]cc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2c1ccnc2c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(C#N)cncnc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1cnoc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c(noc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=c1c2c(n(cc1)c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3n(c4ccccc4)c4c(c3cc3c1C(c1c(cccc1)N3)(C)C)cccc4)cccc2 +c12c(occ1)c(c1c(occ1)c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +O=c1c2c(cccc2)[nH]c(c1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +c12c(cc(nc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]cc1 +N#Cc1c(c(C#N)c(cc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3)C#N +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +O=C1c2c(C(=O)N1)ccc(c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2nc(ccc2ccc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(cccc2)cnc2c1cc(cc2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2c(oc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(ccc(c2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]c2c1ccnc2 +O=C1c2c(C(=O)N1)cccc2c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +N#Cc1ccccc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(cccc2)[nH]c2nccc(c12)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(c2ncc(nc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +n1c2ncc(cc2ccc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(c2nc(cnc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +O=c1c2c(cccc2)[nH]cc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(ccnc2c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]cc1 +n1ccsc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1cnoc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(n(c3c1ccnc3)c1c3n(c4ccccc4)c4c(c3cc3c1C(c1c(cccc1)N3)(C)C)cccc4)cccc2 +O=C1c2c(C(=O)N1c1c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +c12c(occ1)c(c1c(occ1)c2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc2)ccccc1 +c12nc3c(oc(c3)c3c(n4c5c(c6c4cc4c(c6)Nc6c(C4(C)C)cccc6)cccc5)cccc3)nc1[nH]cc2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +N#Cc1ccc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cccc2)cnc2c1c(ccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +O=C(c1ccccc1c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1)C(F)(F)F +n1c2ncccc2c(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cccc2)[nH]c2nccc(c12)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12ncc(nc1cccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(ncc(c2)c2c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc2)ccc1 +c12c(cccc2)c(nc2c1cccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(nc3c(nco3)c2c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)oc1 +n1c2c(cc3c(nc[nH]3)c2c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)cc2)ccccc1 +c12c(sc(c1)c1ccc3c(C(C)(c4c(cccc4)N3)C)c1)cccc2 +c12nc3c(oc(c3)c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)nc1[nH]cc2 +N#Cc1c(C#N)cc(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +N#Cc1c(c(C#N)c(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1)C#N +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1ccc3c(C(C)(c5c(cccc5)N3)C)c1)cccc4)cccc2 +O=c1c2c(ccc(c2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]cc1 +c12c(c(ccc2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]c2ncccc12 +c12c(nn[nH]2)c(ccc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +n1c2ncc(cc2ccc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c1(c2nc(cnc2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)ccccc1 +c12nc3c(occ3c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)nc1[nH]cc2 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +O=C1C=C(C(=O)N1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2nc3nc[nH]c3c(c2[nH]c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(ccnc2)[nH]c(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nccnc2)ccc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +N#Cc1ccc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2)cnc2c1ccc(c2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cc(cc2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2ncccc12 +n1c2c(oc1)ccc(c2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(ccc(c2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2ncccc12 +c1(c2ncccc2)nc(ccc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nccnc2)cccc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +O=c1c2c(c(ccc2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]cc1 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3C(C)(c4c(cccc4)Nc3ccc1)C)cccc2 +c12c(scc1)c(ccc2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(oc1)c(ccc2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(scc1)cccc2c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2c1ccnc2 +O=c1c2c(cccc2c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1oc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(ccc1)ccc1c2ncc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2)[nH]c2ncc(cc12)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12nc3c(occ3)nc1[nH]cc2c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(cc3c(nc(c4c5C(C)(c6c(cccc6)Nc5ccc4)C)[nH]3)c2)[nH]c1 +n1ccsc1c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(c3c(n1c1c4C(C)(c5c(cccc5)Nc4ccc1)C)ccnc3)cncc2 +c12c(n(cc1)c1c3C(C)(c4c(cccc4)Nc3ccc1)C)ccnc2 +CC1(C)c2ccccc2-c2c(-c3cc(C#N)cc(C#N)c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cc4cccnc4c4ncccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4cccnc4n3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4cnc5ccccc5c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4[nH]c5ncccc5c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4[nH]ccc(=O)c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4c3cnc3ccccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4cnc5ccccc5c34)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4[nH]c5ncccc5c34)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc21 +CC1(C)c2ccccc2-c2c(-c3csc4ccccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3nc4nc5nc[nH]c5cc4[nH]3)cccc21 +CC1(C)c2ccccc2-c2c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc21 +CC1(C)c2ccccc2-c2c(-n3ccc4nc5ccoc5nc43)cccc21 +CC1(C)c2ccccc2-c2c(-n3cnc4cc5nc[nH]c5cc43)cccc21 +CC1(C)c2ccccc2-c2c(-n3cnc4nc5nc[nH]c5nc43)cccc21 +CC1(C)c2ccccc2-c2cc(-c3c(C#N)cccc3C#N)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(=O)c4ccccc4[nH]3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(C#N)c(C#N)c(C#N)c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc4cc5occc5cc4o3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc4nc5cc[nH]c5nc4o3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc(-c4ccccn4)n3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc(C#N)c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3C(=O)c=cC4=O)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3cnc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3ncc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3sc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ccnc4[nH]c5ccccc5c34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cnc4[nH]c5ccccc5c4c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3coc4cc5ccoc5cc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3c[nH]c4nc5occc5nc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3nccnc3-c3ccccc3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ncno3)ccc21 +CC1(C)c2ccccc2-c2cc(-n3ccc4cnccc43)ccc21 +CC1(C)c2ccccc2-c2ccc(-c3cc4c(cn3)[nH]c3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cc4cc5occc5cc4o3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc(C#N)c(C#N)c3C#N)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)ncc3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(cnc5ccccc54)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4[nH]c5cnccc5c4c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc4c(=O)cc[nH]c34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc4c3cnc3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccno3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnc(-c4ccccc4)cn3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnc4c(ccc5cccnc54)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnoc3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nccc4c3[nH]c3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nccc4[nH]c5ccncc5c34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ncon3)cc21 +CC1(C)c2ccccc2-c2ccc(-n3c4ccncc4c4cnccc43)cc21 +CC1(C)c2ccccc2-c2ccc(-n3nnc4ccccc43)cc21 +CC1(C)c2ccccc2-c2cccc(-c3c4nc[nH]c4cc4[nH]cnc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c21 +CC1(C)c2ccccc2-c2cccc(-c3cc4ccccc4s3)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc(C#N)c(C#N)c3C#N)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc4c(c3)ncc3ccccc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc4c(c3)[nH]c3ncccc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cccc(C(=O)C(F)(F)F)c3)c21 +O=C1c2c(C(=O)N1)cccc2c1c2C(C)(C)c3c(-c2ccc1)cccc3 +CC1(C)c2ccccc2-c2cccc(-c3cccc4sc5ccccc5c34)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccccc3C#N)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccnc4[nH]c5ccccc5c34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cscn3)c21 +CC1(C)c2ccccc2-c2cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c21 +CC1(C)c2ccccc2-c2cccc(-c3nc4nc5nc[nH]c5cc4[nH]3)c21 +O=C1C=CC(=O)N1N1c2c([C@H](C)c3c1cccc3)cccc2 +N#Cc1cccc(C#N)c1N1c2c(C(C)c3c1cccc3)cccc2 +n1c2nc3nc[nH]c3c(c2[nH]c1)N1c2c(C(C)c3c1cccc3)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)N3c4c(C(C)c5c3cccc5)cccc4)cc2)ccccc1 +N#Cc1cc(cc(C#N)c1)N1c2c(C(C)c3c1cccc3)cccc2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c(C(C)c3c1cccc3)cccc2 +c12c(sc3c1cc(cc3)N1c3c(C(C)c4c1cccc4)cccc3)cccc2 +O=c1c2c(ccc(c2)N2c3c(C(C)c4c2cccc4)cccc3)[nH]cc1 +N#Cc1cccc(c1)N1c2c(C(C)c3c1cccc3)cccc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3N1c2c(C(C)c3c1cccc3)cccc2 +O=C(c1ccccc1N1c2c(C(C)c3c1cccc3)cccc2)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1N1c2c(C(C)c3c1cccc3)cccc2 +n1oc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +n1c2c(ncc(c2)N2c3c(C(C)c4c2cccc4)cccc3)ccc1 +c12c(c3c(c(cnc3)N3c4c(C(C)c5c3cccc5)cccc4)[nH]2)cncc1 +c12nc3c(occ3N3c4c(C(C)c5c3cccc5)cccc4)nc1[nH]cc2 +c12c(c3c(n1N1c4c(C(C)c5c1cccc5)cccc4)ccnc3)cncc2 +n1c2nc3nc[nH]c3cc2n(c1)N1c2c(C(C)c3c1cccc3)cccc2 +N#Cc1cc(C#N)cc(C#N)c1c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3c4c([C@@H](C)c5c(cccc5)N4)ccc3)cc2)ccccc1 +N#Cc1c(c(C#N)c(cc1)c1c2c([C@H](C)c3c(cccc3)N2)ccc1)C#N +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +n1c2c(oc1)cc(cc2)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +c12c(scc1)ccc(c2)c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +c12c(c(ccc2)c2c3c([C@@H](C)c4c(cccc4)N3)ccc2)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nccc1c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +c12c(c(cnc2)c2c3c([C@H](C)c4c(cccc4)N3)ccc2)[nH]cc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +O=c1c2c(cccc2)[nH]cc1c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +N#Cc1cc(C#N)cc(C#N)c1c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2cc3c([C@H](C)c4c(cccc4)N3)cc2)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1cc3c([C@H](C)c5c(cccc5)N3)cc1)cccc4)cccc2 +c12c(c3c(cc(nc3)c3cc4c([C@H](C)c5c(cccc5)N4)cc3)[nH]2)cncc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(sc3c1ccc(c3)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +n1c2nc(ccc2ccc1)c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +c12c(cccc2)cnc2c1cc(cc2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(sc3c1cc(cc3)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +O=c1c2c(ccc(c2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(c(ccc2)c2cc3c([C@H](C)c4c(cccc4)N3)cc2)cnc2c1cccc2 +c12c(sc3c1c(ccc3)c1cc3c([C@H](C)c4c(cccc4)N3)cc1)cccc2 +c1(c2ncccc2c2cc3c([C@H](C)c4c(cccc4)N3)cc2)ncccc1 +n1c2c(ncc(c2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)ccc1 +c1(c2nc(cnc2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)ccccc1 +n1c2nc3nc(c4cc5c([C@@H](C)c6c(cccc6)N5)cc4)[nH]c3cc2[nH]c1 +c12c(n(c3c1ccnc3)c1cc3c([C@H](C)c4c(cccc4)N3)cc1)cccc2 +c12nc3c(occ3)nc1n(cc2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +O=C1C=C(C(=O)N1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +N#Cc1c(c(C#N)cc(c1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1)C#N +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2ccc3c([C@@H](C)c4c(cccc4)N3)c2)ccccc1 +c12c(cc(nc2)c2ccc3c([C@H](C)c4c(cccc4)N3)c2)[nH]cc1 +N#Cc1c(c(C#N)c(cc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1)C#N +N#Cc1ccc(cc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=C(c1ccc(cc1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1)C(F)(F)F +c12c(ccc(c2)c2ccc3c([C@H](C)c4c(cccc4)N3)c2)cnc2c1cccc2 +c12c(nn[nH]2)ccc(c1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1 +c12nccnc1c(ccc2)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c2c(oc1)c(ccc2)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c2c(oc1)cccc2c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +N#Cc1ccccc1c1ccc2c([C@@H](C)c3c(cccc3)N2)c1 +O=C(c1ccccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1)C(F)(F)F +c1(c2ncccc2c2ccc3c([C@H](C)c4c(cccc4)N3)c2)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=c1c2c(cccc2)[nH]cc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c(noc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=c1c2c(n(cc1)c1ccc3c([C@@H](C)c4c(cccc4)N3)c1)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(ccc2)Nc2c([C@@H]3C)cccc2)[nH]c1 +c12c(cccc2)[nH]c2c1cc(nc2)c1c2c(ccc1)Nc1c([C@@H]2C)cccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +n1c2c(oc1)ccc(c2)c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +c1(c2ncccc2c2c3c(ccc2)Nc2c([C@@H]3C)cccc2)ncccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1c2c(ccc1)Nc1c([C@@H]2C)cccc1 +n1c2c(cc3c(nc(c4c5c(ccc4)Nc4c([C@H]5C)cccc4)[nH]3)c2)[nH]c1 +n1ccsc1c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +n1cnoc1c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +Cc1-c2ccccc2-c2c(-c3c4ncoc4cc4ncoc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cc4c(cn3)[nH]c3ccccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cccc2-1 +C[C@@H]1c2c(-c3c1cccc3c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +C[C@H]1c2c(-c3c1cccc3c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +Cc1-c2ccccc2-c2c(-c3ccc4cc(N(C)C)ccc4c3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)cccc2-1 +C[C@H]1c2c(-c3c1cccc3c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +C[C@@H]1c2c(-c3c1cccc3c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +Cc1-c2ccccc2-c2c(-c3cccc4c3oc3ccccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4c3Oc3ccccc3O4)cccc2-1 +C[C@H]1c2c(-c3c1cccc3c1c3n(c4ccccc4)c4c(c3ccc1)cc1c(C(c3c(cccc3)N1)(C)C)c4)cccc2 +Cc1-c2ccccc2-c2c(-c3cccc4ncoc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4oc5ncccc5c34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4sccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4[nH]nnc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccccc3N(c3ccccc3)c3ccccc3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccccc3N)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cnc4sc5ncccc5c4c3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cncc4[nH]c5ccccc5c34)cccc2-1 +C[C@H]1c2c(-c3c1cccc3N1c3c(Sc4c1cccc4)cccc3)cccc2 +Cc1-c2ccccc2-c2c-1cccc2-n1nnc2ccccc21 +C[C@H]1c2c(-c3c1ccc(c3)N1c3c([C@@H](C)c4c1cccc4)cccc3)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)N1c3c(CCc4c1cccc4)cccc3)cccc2 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +Cc1-c2ccccc2-c2cc(-c3c4ccoc4cc4ccoc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3c4ncoc4cc4ncoc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cc4cc5occc5cc4o3)ccc2-1 +C[C@H]1c2c(-c3c1ccc(c3)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)Oc3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4cnc5ccccc5c4c3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4oc5ncccc5c4c3)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c([C@H](C)c4c(cccc4)N3)ccc1)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3cccc4c3-c3ccccc3C4(C)C)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +Cc1-c2ccccc2-c2cc(-c3cccc4c3cnc3ccccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3N(C)c3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3Oc3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3[nH]c3ccncc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c5nc[nH]c5c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4cc(N(C)C)ccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4nn[nH]c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4oc5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cn[nH]c3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3c[nH]c4ccccc4c3=O)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nc4cc5ocnc5cc4o3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nc4cc5scnc5cc4s3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nccc4[nH]c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccccc4c4ccncc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccncc4c4cnccc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3ccc4nc5ccoc5nc43)ccc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc(N(C)C)c4ccccc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4cc5occc5cc4o3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4ccccc4cc3N(C)C)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4ccccc4[nH]3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)N(C)c3ccccc3O4)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)sc3ncccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(N(C)C)cccc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4cccc(N(C)C)c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4occc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4[nH]c5ccccc5c(=O)c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3cnc3ccccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3oc3ccccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3sc3ncccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4[nH]c5ccccc5c(=O)c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccn[nH]3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cn[nH]c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3coc4cc5ccoc5cc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3coc4cc5[nH]ccc5cc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3c[nH]c4ccccc4c3=O)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3nc4ccccc4s3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3nccc4[nH]c5ccccc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-n3c4ccccc4c(=O)c4ccccc43)cc2-1 +Cc1-c2ccccc2-c2ccc(-n3c4ccccc4c4cnccc43)cc2-1 +Cc1-c2ccccc2-c2cccc(-c3cc(=O)c4ccccc4[nH]3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc(N(C)C)cc4ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4c(cn3)[nH]c3ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4ccccc4cc3N(C)C)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc(N(C)C)c4ccccc34)c2-1 +C[C@@H]1c2c(-c3c1c(ccc3)c1ccc3c(c1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)N(C)c3ccccc3O4)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)oc3ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)c2-1 +C[C@H]1c2c(-c3c1c(ccc3)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +Cc1-c2ccccc2-c2cccc(-c3ccc4c5ccccc5c5nccnc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cc(N(C)C)ccc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4ccc(N(C)C)cc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4ccsc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cc[nH]c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cnc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4oc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4[nH]c5ccncc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4c(N(C)C)cccc34)c2-1 +C[C@@H]1c2c(-c3c1c(ccc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +C[C@H]1c2c(-c3c1c(ccc3)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +Cc1-c2ccccc2-c2cccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cccc(N(C)C)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4ccsc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cc[nH]c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cnc5ccccc5c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4occc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]c5ccccc5c(=O)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]nnc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccccc3N)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cnc4sc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4cc5scnc5cc4s3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4ccccc4c4ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4ccccc4s3)c2-1 +Cc1-c2ccccc2-c2cccc(-n3c4ccncc4c4cnccc43)c2-1 +Cc1-c2ccccc2-c2cccc(-n3ccc(=O)c4ccccc43)c2-1 +Cc1-c2ccccc2-c2cccc(-n3cccn3)c2-1 +Cc1c(C)c(-c2c(F)c(F)c(F)c(F)c2F)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2c3ccoc3cc3ccoc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2c3[nH]cnc3cc3nc[nH]c23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cc(C#N)cc(C#N)c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cc3nc4ccoc4nc3[nH]2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc(-c3cnccn3)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc(C#N)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(c2)-c2ccccc2-s-3(=O)=O)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(c2)[nH]c2ncccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(n2)[nH]c2ccccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3ncc4ccccc4c3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3ncoc3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc(-c3ccccn3)n2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc(C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3c2-s(=O)(=O)-c2ccccc2-3)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3c2cnc2ccccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3ocnc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccccc2C(=O)C(F)(F)F)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccccc2C(=O)c2ccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cnc3ccccc3n2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cnc3cccnc3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2c3ccccc3c3cccnc32)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2ccc(=O)c3ccccc32)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2ccc3nc4ccoc4nc32)c2c(c1C)c1ccccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3c4nc[nH]c4cc4[nH]cnc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc(C#N)c(C#N)c(C#N)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc(C#N)cc(C#N)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4cccnc4c4ncccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4cnccc4[nH]3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4nc5cc[nH]c5nc4o3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4[nH]c5ccncc5c4cn3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc(C#N)c(C#N)c3C#N)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4c(c3)sc3ccccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4ccc5cccnc5c4n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4nccnc4c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(-c4ccccn4)n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(C(=O)C(F)(F)F)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4c(=O)cc[nH]c34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4c3[nH]c3cnccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4nn[nH]c34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccnc(-c4ccccn4)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cnc4nccnc4n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3nccc4c3[nH]c3ccccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ncon3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-n3cnc4nc5nc[nH]c5cc43)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-n3nnc4ccccc43)cccc1n2C +O=C1c2c(C(=O)N1c1cc3c4c(n(c3cc1)C)cc(C)c(c4C)C)cccc2 +Cc1cc2c(c(C)c1C)c1cc(-c3c(C#N)cccc3C#N)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4ccccc4s3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4nc5ccoc5nc4[nH]3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4[nH]ccc4cn3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)-c(C)-c3ccccc3-4)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)sc3ccccc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4nccnc4c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc(C#N)c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc(C(=O)C(F)(F)F)c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc4c3C(=O)c=cC4=O)ccc1n2C +O=C1c2c(C(=O)N1)cccc2c1cc2c3c(n(c2cc1)C)cc(C)c(c3C)C +Cc1cc2c(c(C)c1C)c1cc(-c3ccccc3C#N)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccnc4ncccc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccon3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cncc4[nH]c5ccccc5c34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cnoc3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3coc4cc5ccoc5cc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ncon3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-n3c4ccccc4c4cccnc43)ccc1n2C +O=C1c2c(C(=O)N1c1ccc3c4c(n(c3c1)C)cc(C)c(c4C)C)cccc2 +O=C1C=CC(=O)N1c1ccc2c3c(n(c2c1)C)cc(C)c(c3C)C +Cc1cc2c(c(C)c1C)c1ccc(-c3c(C#N)cc(C#N)cc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3c4nc[nH]c4cc4[nH]cnc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc(C#N)cc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4c(=O)cc[nH]c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4ccsc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4nn[nH]c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4sccc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4[nH]c5cnccc5c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4[nH]nnc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc4sc5ccccc5c34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc4[nH]ccc(=O)c34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cnc4c(ccc5cccnc54)c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3c[nH]c4ccncc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3nccc4c3[nH]c3ccccc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3nccc4[nH]ccc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ncncc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cc4[nH]c5ccncc5c4cn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(C#N)c(C#N)c3C#N)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(C#N)cc3C#N)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4ncccc4n3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4[nH]c5cnccc5c4c3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4[nH]ccc(=O)c4c3)c1n2C +O=C1c2c(C(=O)N1)cccc2c1c2c(c3c(n2C)cc(C)c(c3C)C)ccc1 +Cc1cc2c(c(C)c1C)c1cccc(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cccc4[nH]ccc(=O)c34)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cccnc3-c3ccccn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cnc4cccnc4c3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cncc4c3[nH]c3ccncc34)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cscn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ncc(C#N)cn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3nccc4[nH]ccc34)c1n2C +Cc1cccc2c1[nH]c1c(C)c(-c3c(C#N)cccc3C#N)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3c4ncoc4nc4ocnc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccc(F)cc5)n4)ccc3F)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc(C#N)c(C#N)c(C#N)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc4cccnc4c4ncccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc4[nH]ccc4cn3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc(C#N)c(C#N)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc(C#N)cc3C#N)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc4sc5ccccc5c4c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc4[nH]nnc4c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc(C(=O)C(F)(F)F)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3ncc3ccccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3[nH]c3ncccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4ncoc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccnc3-c3ccccn3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccnc(-c4ccccn4)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccno3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cnc4ccccc4n3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3coc4nc5[nH]ccc5nc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3c[nH]c4ccncc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-n3c4ccccc4c4cccnc43)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-n3ccc(=O)c4ccccc43)ccc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3(C)-c4ccccc4-c4ccccc4-3)cc12 +O=C1C=C(C(=O)N1)c1cc2c3c(c(C)ccc3)[nH]c2c(C)c1 +Cc1cccc2c1[nH]c1c(C)cc(-c3c4[nH]cnc4nc4nc[nH]c34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cc(C#N)cc(C#N)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cc4[nH]c5ccncc5c4cn3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc(C#N)c(C#N)c3C#N)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc(C#N)cc3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)cc12 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c3c(c(C)ccc3)[nH]c2c(C)c1 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)[nH]c3ncccc34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4nccnc4c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4ocnc4c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(-c4ccccn4)n3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(-c4cnccn4)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4c3-c(C)-c3ccccc3-4)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4c3ncc3ccccc34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4[nH]c5ncccc5c34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccon3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cnc(-c4ccccc4)cn3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cnc4ccccc4n3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3csc4ccccc34)cc12 +O=C1c2c(C(=O)N1c1c3c4c(c(C)ccc4)[nH]c3c(C)cc1)cccc2 +Cc1cccc2c1[nH]c1c(C)ccc(-c3c4ccoc4cc4ccoc34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc(C#N)c(C#N)c(C#N)c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc4[nH]ccc4cn3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(-c4cnccn4)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C#N)c(C#N)c3C#N)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C(=O)C(F)(F)F)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4c(=O)cc[nH]c4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4cnc5ccccc5c4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4[nH]nnc4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cccc4c3-c(C)-c3ccccc3-4)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cccc4[nH]c5ncccc5c34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccnc4cccnc34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cnc4c(ccc5cccnc54)c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cnc4cccnc4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cncs3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cscn3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-n3cnc4cc5nc[nH]c5cc43)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-n3cnc4nc5nc[nH]c5cc43)c12 +O=C1C=C(C(=O)N1)n1c2c(c3c1c(C)ccc3)cccc2C +Cc1cccc2c3cccc(C)c3n(-c3c4ncoc4nc4ocnc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3c4[nH]cnc4cc4nc[nH]c34)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccc(F)cc5)n4)ccc3F)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc(=O)c4ccccc4[nH]3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc4nc5cc[nH]c5nc4o3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc4[nH]ccc4cn3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(c3)-c(C)-c3ccccc3-4)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(c3)-c3ccccc3-c-4C)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(n3)[nH]c3ccccc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4ncc5ccccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4[nH]c5ncccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cccc4c3-c3ccccc3-s-4(=O)=O)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccno3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4ccccc4n3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4cccnc4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4[nH]c5ccccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cncc4[nH]c5ccccc5c34)c12 +Cc1cccc2c3cccc(C)c3n(-c3csc4ccccc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3nc4nc5nc[nH]c5nc4[nH]3)c12 +Cc1cccc2c3cccc(C)c3n(-c3nccc4[nH]c5ccncc5c34)c12 +Cc1cccc2c3cccc(C)c3n(-n3ccc4nc5ccoc5nc43)c12 +CN(C)c1c(-c2(C)-c3ccccc3-c3ccccc3-2)ccc2ccccc12 +O=C1C=CC(=O)N1c1c(N(C)C)c2c(cc1)cccc2 +CN(C)c1c(-c2c3[nH]cnc3nc3nc[nH]c23)ccc2ccccc12 +CN(C)c1c(-c2cc(C#N)c(C#N)c(C#N)c2)ccc2ccccc12 +CN(C)c1c(-c2cc(F)ccc2-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)ccc2ccccc12 +CN(C)c1c(-c2cccc(C(=O)C(F)(F)F)c2)ccc2ccccc12 +CN(C)c1c(-c2cccc3c2[nH]c2ncccc23)ccc2ccccc12 +CN(C)c1c(-c2cccc3cnc4ccccc4c23)ccc2ccccc12 +CN(C)c1c(-c2cccc3ncoc23)ccc2ccccc12 +CN(C)c1c(-c2ccon2)ccc2ccccc12 +CN(C)c1c(-c2cnoc2)ccc2ccccc12 +CN(C)c1c(-c2c[nH]c3ccncc23)ccc2ccccc12 +CN(C)c1c(-c2nc3cc4nc[nH]c4cc3[nH]2)ccc2ccccc12 +CN(C)c1c(-c2nc3ccccc3o2)ccc2ccccc12 +CN(C)c1c(-n2c3ccccc3c3cccnc32)ccc2ccccc12 +CN(C)c1cc(-c2c3ncoc3nc3ocnc23)cc2ccccc12 +CN(C)c1cc(-c2c3[nH]cnc3nc3nc[nH]c23)cc2ccccc12 +CN(C)c1cc(-c2cc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2C(=O)c2ccccc2)c2ccccc2c1 +CN(C)c1cc(-c2cc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2C(=O)c2ccccc2)cc2ccccc12 +CN(C)c1cc(-c2cc(=O)c3ccccc3[nH]2)c2ccccc2c1 +CN(C)c1cc(-c2cc3cccnc3c3ncccc23)c2ccccc2c1 +CN(C)c1cc(-c2ccc(-c3cnccn3)cc2)c2ccccc2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(cccc2)cc(N(C)C)c1 +CN(C)c1cc(-c2ccc3c(c2)[nH]c2ncccc23)cc2ccccc12 +CN(C)c1cc(-c2ccc3c(cnc4ccccc43)c2)c2ccccc2c1 +CN(C)c1cc(-c2ccc3c(cnc4ccccc43)c2)cc2ccccc12 +CN(C)c1cc(-c2ccc3c(n2)[nH]c2ccccc23)cc2ccccc12 +CN(C)c1cc(-c2ccc3ncoc3c2)cc2ccccc12 +CN(C)c1cc(-c2ccc3nn[nH]c3c2)c2ccccc2c1 +CN(C)c1cc(-c2ccc3[nH]c4cnccc4c3c2)cc2ccccc12 +CN(C)c1cc(-c2cccc(-c3cnccn3)c2)c2ccccc2c1 +CN(C)c1cc(-c2cccc(C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c2)cc2ccccc12 +CN(C)c1cc(-c2cccc3c(=O)cc[nH]c23)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2C(=O)c=cC3=O)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2ncc2ccccc23)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2[nH]c2cnccc23)c2ccccc2c1 +CN(C)c1cc(-c2cccc3c2[nH]c2cnccc23)cc2ccccc12 +CN(C)c1cc(-c2cccc3nccnc23)c2ccccc2c1 +CN(C)c1cc(-c2cccc3ocnc23)c2ccccc2c1 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c2ccccc2c1 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc2ccccc12 +CN(C)c1cc(-c2cccnc2-c2ccccn2)c2ccccc2c1 +CN(C)c1cc(-c2ccnc(-c3ccccn3)c2)c2ccccc2c1 +CN(C)c1cc(-c2ccnc3c2ccc2cccnc23)c2ccccc2c1 +CN(C)c1cc(-c2ccnc3cccnc23)c2ccccc2c1 +CN(C)c1cc(-c2coc3nc4[nH]ccc4nc23)cc2ccccc12 +CN(C)c1cc(-c2csc3ccccc23)c2ccccc2c1 +CN(C)c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2ccccc2c1 +CN(C)c1cc(-c2nccs2)cc2ccccc12 +CN(C)c1cc(-n2cnc3cc4nc[nH]c4cc32)cc2ccccc12 +CN(C)c1cc2ccccc2cc1-c1(C)-c2ccccc2-c2ccccc2-1 +O=C1C=C(C(=O)N1)c1c(N(C)C)cc2c(c1)cccc2 +O=C1c2c(C(=O)N1c1c(N(C)C)cc3c(c1)cccc3)cccc2 +O=C1C=CC(=O)N1c1c(N(C)C)cc2c(c1)cccc2 +CN(C)c1cc2ccccc2cc1-c1c(C#N)cc(C#N)cc1C#N +CN(C)c1cc2ccccc2cc1-c1c(F)c(F)c(F)c(F)c1F +CN(C)c1cc2ccccc2cc1-c1cc(C#N)c(C#N)c(C#N)c1 +CN(C)c1cc2ccccc2cc1-c1cc2c3c(c1)Oc1ccccc1B3c1ccccc1O2 +CN(C)c1cc2ccccc2cc1-c1cc2ccccc2s1 +CN(C)c1cc2ccccc2cc1-c1cc2cnccc2[nH]1 +CN(C)c1cc2ccccc2cc1-c1cc2nc3ccoc3nc2[nH]1 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)-c1ccccc1-s-2(=O)=O +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)-s(=O)(=O)-c1ccccc1-2 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)B1c3ccccc3Oc3cccc(c31)O2 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)Oc1cccc3c1B2c1ccccc1O3 +CN(C)c1cc2ccccc2cc1-c1ccc2cnc3ccccc3c2c1 +CN(C)c1cc2ccccc2cc1-c1cccc2ocnc12 +CN(C)c1cc2ccccc2cc1-c1ccnc2c1ccc1cccnc12 +CN(C)c1cc2ccccc2cc1-c1ccnc2ncccc12 +CN(C)c1cc2ccccc2cc1-c1cncs1 +CN(C)c1cc2ccccc2cc1-c1coc2nc3[nH]ccc3nc12 +CN(C)c1cc2ccccc2cc1-c1nccnc1-c1ccccc1 +CN(C)c1cc2ccccc2cc1-n1cnc2nc3nc[nH]c3cc21 +CN(C)c1ccc(-c2=cC(=O)c3ccccc3C2=O)c2ccccc12 +CN(C)c1ccc(-c2c(F)c(F)c(F)c(F)c2F)c2ccccc12 +CN(C)c1ccc(-c2cc(-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)ccc2F)c2ccccc12 +CN(C)c1ccc(-c2cc3cnccc3[nH]2)c2ccccc12 +CN(C)c1ccc(-c2cc3[nH]c4ccncc4c3cn2)c2ccccc12 +CN(C)c1ccc(-c2ccc(-c3cnccn3)cc2)c2ccccc12 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c(N(C)C)cc1)cccc2 +CN(C)c1ccc(-c2ccc3c(c2)sc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2ccc3ccsc3c2)c2ccccc12 +CN(C)c1ccc(-c2ccc3[nH]nnc3c2)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2ncc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2sc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2[nH]c2cnccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3nccnc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3ocnc23)c2ccccc12 +CN(C)c1ccc(-c2ccnc3cccnc23)c2ccccc12 +CN(C)c1ccc(-c2ccno2)c2ccccc12 +CN(C)c1ccc(-c2nccnc2-c2ccccc2)c2ccccc12 +CN(C)c1ccc(-c2ncon2)c2ccccc12 +CN(C)c1ccc(-n2c3ccncc3c3cnccc32)c2ccccc12 +CN(C)c1ccc(-n2ccc3cnccc32)c2ccccc12 +CN(C)c1ccc(-n2cnc3cc4nc[nH]c4cc32)c2ccccc12 +CN(C)c1ccc(-n2cnc3nc4nc[nH]c4nc32)c2ccccc12 +CN(C)c1ccc2c(-c3c(F)c(F)c(F)c(F)c3F)cccc2c1 +CN(C)c1ccc2c(-c3c4[nH]cnc4nc4nc[nH]c34)cccc2c1 +CN(C)c1ccc2c(-c3cc4[nH]c5ccncc5c4cn3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4c(=O)cc[nH]c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4c(c3)ncc3ccccc34)cccc2c1 +CN(C)c1ccc2c(-c3ccc4cccnc4n3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4cnc5ccccc5c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4[nH]ccc(=O)c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc2c1 +CN(C)c1ccc2c(-c3ccno3)cccc2c1 +CN(C)c1ccc2c(-c3ncc(C#N)cn3)cccc2c1 +CN(C)c1ccc2c(-n3ccc(=O)c4ccccc43)cccc2c1 +CN(C)c1ccc2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc2c1 +CN(C)c1ccc2cc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)ccc2c1 +CN(C)c1ccc2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc2c1 +CN(C)c1ccc2cc(-c3cc4[nH]c5ccncc5c4cn3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc(-c4cnccn4)cc3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc4nn[nH]c4c3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc4sccc4c3)ccc2c1 +CN(C)c1ccc2cc(-c3cccc4c3sc3ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3cccc4ocnc34)ccc2c1 +CN(C)c1ccc2cc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2c1 +CN(C)c1ccc2cc(-c3ccccc3C#N)ccc2c1 +CN(C)c1ccc2cc(-c3cnc4nccnc4n3)ccc2c1 +CN(C)c1ccc2cc(-c3csc4ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3nc4ccccc4c4ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3nc4nc5nc[nH]c5nc4[nH]3)ccc2c1 +CN(C)c1ccc2cc(-c3nccs3)ccc2c1 +CN(C)c1ccc2cc(-n3c4ccccc4c4ccncc43)ccc2c1 +O=C1C=C(C(=O)N1)c1ccc2c(c1)cc(N(C)C)cc2 +CN(C)c1ccc2ccc(-c3cc(=O)c4ccccc4[nH]3)cc2c1 +CN(C)c1ccc2ccc(-c3ccc(C#N)c(C#N)c3C#N)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4c(c3)C(=O)c=cC4=O)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4ncccc4n3)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4[nH]c5ncccc5c4c3)cc2c1 +CN(C)c1ccc2ccc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cc2c1 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c1)cc(N(C)C)cc2 +CN(C)c1ccc2ccc(-c3cccc4ccsc34)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4[nH]c5ncccc5c34)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4[nH]ccc(=O)c34)cc2c1 +CN(C)c1ccc2ccc(-c3ccnc4ncccc34)cc2c1 +CN(C)c1ccc2ccc(-c3cncc4cc[nH]c34)cc2c1 +CN(C)c1ccc2ccc(-n3ccc4cnccc43)cc2c1 +CN(C)c1ccc2ccc(-n3cnc4nc5nc[nH]c5nc43)cc2c1 +CN(C)c1ccc2cccc(-c3c4[nH]cnc4cc4nc[nH]c34)c2c1 +CN(C)c1ccc2cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c2c1 +CN(C)c1ccc2cccc(-c3cc(F)ccc3-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)c2c1 +CN(C)c1ccc2cccc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)c2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccc(N(C)C)c2)ccc1 +CN(C)c1ccc2cccc(-c3ccc4c(c3)[nH]c3ncccc34)c2c1 +CN(C)c1ccc2cccc(-c3ccc4c(n3)[nH]c3ccccc34)c2c1 +CN(C)c1ccc2cccc(-c3ccc4ncoc4c3)c2c1 +CN(C)c1ccc2cccc(-c3cccc(C(=O)C(F)(F)F)c3)c2c1 +CN(C)c1ccc2cccc(-c3cccc4c(=O)cc[nH]c34)c2c1 +CN(C)c1ccc2cccc(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)c2c1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc(N(C)C)c2)ccc1 +CN(C)c1ccc2cccc(-c3cccc4ccsc34)c2c1 +CN(C)c1ccc2cccc(-c3cccnc3-c3ccccn3)c2c1 +CN(C)c1ccc2cccc(-c3ccnc4c3ccc3cccnc34)c2c1 +CN(C)c1ccc2cccc(-c3ccnc4cccnc34)c2c1 +CN(C)c1ccc2cccc(-c3cnc4c(ccc5cccnc54)c3)c2c1 +CN(C)c1ccc2cccc(-c3cnc4ncccc4c3)c2c1 +CN(C)c1ccc2cccc(-c3c[nH]c4ccncc34)c2c1 +CN(C)c1ccc2cccc(-c3nccs3)c2c1 +CN(C)c1ccc2cccc(-n3c4ccccc4c4ccncc43)c2c1 +CN(C)c1ccc2ccccc2c1-c1cc(C(=O)c2ccccc2)ccc1-c1nc(-c2ccc(F)cc2)nc(-c2ccc(F)cc2)n1 +CN(C)c1ccc2ccccc2c1-c1cc(F)ccc1-c1nc(-c2ccc(F)cc2)nc(-c2ccc(C(=O)c3ccccc3)cc2)n1 +CN(C)c1ccc2ccccc2c1-c1cc2nc3ccoc3nc2[nH]1 +CN(C)c1ccc2ccccc2c1-c1cc2nc3cc[nH]c3nc2o1 +CN(C)c1ccc2ccccc2c1-c1ccc(C#N)c(C#N)c1C#N +CN(C)c1ccc2ccccc2c1-c1ccc2c(cnc3ccccc32)c1 +CN(C)c1ccc2ccccc2c1-c1ccc2ccsc2c1 +CN(C)c1ccc2ccccc2c1-c1cccc(C#N)c1 +CN(C)c1ccc2ccccc2c1-c1cccc(C(=O)c2ccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc2)c1 +CN(C)c1ccc2ccccc2c1-c1cccc2c1-s(=O)(=O)-c1ccccc1-2 +O=C1c2c(C(=O)N1)cccc2c1c(N(C)C)ccc2c1cccc2 +CN(C)c1ccc2ccccc2c1-c1cnc2ccccc2n1 +CN(C)c1ccc2ccccc2c1-c1cncs1 +CN(C)c1ccc2ccccc2c1-c1ncon1 +CN(C)c1cccc2c(-c3c(C#N)cc(C#N)cc3C#N)cccc12 +CN(C)c1cccc2c(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cccc12 +CN(C)c1cccc2c(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cccc12 +CN(C)c1cccc2c(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc12 +CN(C)c1cccc2c(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)cccc12 +CN(C)c1cccc2c(-c3ccc4ncc5ccccc5c4c3)cccc12 +CN(C)c1cccc2c(-c3ccc4ncccc4n3)cccc12 +CN(C)c1cccc2c(-c3ccc4[nH]nnc4c3)cccc12 +CN(C)c1cccc2c(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cccc12 +CN(C)c1cccc2c(-c3cccc4c3[nH]c3cnccc34)cccc12 +CN(C)c1cccc2c(-c3cccc4c3[nH]c3ncccc34)cccc12 +CN(C)c1cccc2c(-c3cccc4ccsc34)cccc12 +CN(C)c1cccc2c(-c3cccc4ncc5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3cccc4sc5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3cccc4[nH]ccc(=O)c34)cccc12 +CN(C)c1cccc2c(-c3ccccc3C(=O)C(F)(F)F)cccc12 +CN(C)c1cccc2c(-c3ccnc4cccnc34)cccc12 +CN(C)c1cccc2c(-c3cncc4[nH]c5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3c[nH]c4ccncc34)cccc12 +CN(C)c1cccc2c(-n3c4ccccc4c4ccncc43)cccc12 +CN(C)c1cccc2cc(-c3c(C#N)cccc3C#N)ccc12 +CN(C)c1cccc2cc(-c3ccc(-c4cnccn4)cc3)ccc12 +CN(C)c1cccc2cc(-c3ccc(C#N)cc3)ccc12 +CN(C)c1cccc2cc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)ccc12 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(c(N(C)C)ccc2)cc1 +CN(C)c1cccc2cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +CN(C)c1cccc2cc(-c3ccc4nn[nH]c4c3)ccc12 +CN(C)c1cccc2cc(-c3cccc(C#N)c3)ccc12 +CN(C)c1cccc2cc(-c3cccc4[nH]c5cnccc5c34)ccc12 +CN(C)c1cccc2cc(-c3cccc4[nH]nnc34)ccc12 +CN(C)c1cccc2cc(-c3ccccc3-c3cnccn3)ccc12 +CN(C)c1cccc2cc(-c3cnc4ncccc4c3)ccc12 +CN(C)c1cccc2cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +CN(C)c1cccc2cc(-c3cscn3)ccc12 +CN(C)c1cccc2cc(-c3c[nH]c4ccccc4c3=O)ccc12 +CN(C)c1cccc2cc(-c3c[nH]c4ccncc34)ccc12 +CN(C)c1cccc2cc(-c3nccc4c3[nH]c3ccccc34)ccc12 +CN(C)c1cccc2cc(-c3nccc4[nH]ccc34)ccc12 +CN(C)c1cccc2cc(-c3ncncc3C#N)ccc12 +CN(C)c1cccc2ccc(-c3cc(=O)c4ccccc4[nH]3)cc12 +CN(C)c1cccc2ccc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cc12 +CN(C)c1cccc2ccc(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cc12 +CN(C)c1cccc2ccc(-c3cccc4c3[nH]c3ncccc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4ocnc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4sccc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4[nH]c5ncccc5c34)cc12 +CN(C)c1cccc2ccc(-c3cccc4[nH]nnc34)cc12 +CN(C)c1cccc2ccc(-c3ccnc4cccnc34)cc12 +CN(C)c1cccc2ccc(-c3ccno3)cc12 +CN(C)c1cccc2ccc(-c3coc4cc5ccoc5cc34)cc12 +CN(C)c1cccc2ccc(-n3ccc(=O)c4ccccc43)cc12 +CN(C)c1cccc2cccc(-c3c(C#N)cc(C#N)cc3C#N)c12 +CN(C)c1cccc2cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c12 +CN(C)c1cccc2cccc(-c3cc(C#N)cc(C#N)c3)c12 +CN(C)c1cccc2cccc(-c3cc4cc5occc5cc4o3)c12 +CN(C)c1cccc2cccc(-c3ccc(C#N)cc3C#N)c12 +CN(C)c1cccc2cccc(-c3ccc4cccnc4n3)c12 +CN(C)c1cccc2cccc(-c3ccc4ocnc4c3)c12 +CN(C)c1cccc2cccc(-c3cccc4c3[nH]c3ncccc34)c12 +CN(C)c1cccc2cccc(-c3cccc4[nH]c5ncccc5c34)c12 +CN(C)c1cccc2cccc(-c3coc4cc5ccoc5cc34)c12 +CN(C)c1cccc2cccc(-c3coc4nc5[nH]ccc5nc34)c12 +CN(C)c1cccc2cccc(-c3nc4ccccc4c4ccccc34)c12 +CN(C)c1cccc2cccc(-c3nc4ccccc4o3)c12 +CN(C)c1cccc2cccc(-c3nccc4[nH]c5ccncc5c34)c12 +CN(C)c1cccc2cccc(-c3ncncc3C#N)c12 +CN(C)c1cccc2cccc(-n3c4ccccc4c4ccncc43)c12 +CN(C)c1cccc2cccc(-n3ccc4nc5ccoc5nc43)c12 +CN(C)c1cccc2cccc(-n3cnc4cc5nc[nH]c5cc43)c12 +CN(C)c1cccc2cccc(-n3cnc4nc5nc[nH]c5nc43)c12 +CN1c2ccccc2N(C)c2c(-c3=cC(=O)c4ccccc4C3=O)cccc21 +CN1c2ccccc2N(C)c2c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc4[nH]c5ccncc5c4cn3)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc4[nH]ccc4cn3)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4c(c3)sc3ccccc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4cccnc4n3)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4ncc5ccccc5c4c3)cccc21 +O=C1c2c(C(=O)N1)cccc2c1c2N(C)c3c(N(C)c2ccc1)cccc3 +CN1c2ccccc2N(C)c2c(-c3cccc4ocnc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3cnc4cccnc4c3)cccc21 +CN1c2ccccc2N(C)c2c(-c3c[nH]c4nc5occc5nc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3ncc(C#N)cn3)cccc21 +CN1c2ccccc2N(C)c2c1cccc2-n1ccc(=O)c2ccccc21 +CN1c2ccccc2N(C)c2c1cccc2-n1nnc2ccccc21 +CN1c2ccccc2N(C)c2cc(-c3=cC(=O)c4ccccc4C3=O)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cc4ccccc4s3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc(C#N)c(C#N)c3C#N)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc4ncoc4c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc4ccsc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccnc(-c4ccccn4)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cnc4c(ccc5cccnc54)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cncc(-c4ccccc4)n3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cncc4[nH]c5ccccc5c34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3csc4ccccc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3c[nH]c4nc5occc5nc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ncon3)ccc21 +CN1c2ccccc2N(C)c2cc(-n3ccc(=O)c4ccccc43)ccc21 +CN1c2ccccc2N(C)c2cc(-n3ccc4cnccc43)ccc21 +O=C1C=C(C(=O)N1)c1c2Oc3c(N(C)c2ccc1)cccc3 +CN1c2ccccc2Oc2c(-c3c(C#N)cc(C#N)cc3C#N)cccc21 +CN1c2ccccc2Oc2c(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)ccc3C(=O)c3ccccc3)cccc21 +CN1c2ccccc2Oc2c(-c3cc4cnccc4[nH]3)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)C(=O)c=cC4=O)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)[nH]c3ncccc34)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4nn[nH]c4c3)cccc21 +CN1c2ccccc2Oc2c(-c3cccc(-c4cnccn4)c3)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3ncc3ccccc34)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4cnc5ccccc5c34)cccc21 +CN1c2ccccc2Oc2c(-c3ccon3)cccc21 +CN1c2ccccc2Oc2c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc21 +CN1c2ccccc2Oc2c(-c3ncc(C#N)cn3)cccc21 +CN1c2ccccc2Oc2c(-c3ncno3)cccc21 +CN1c2ccccc2Oc2c1cccc2-n1nnc2ccccc21 +CN1c2ccccc2Oc2cc(-c3(C)-c4ccccc4-c4ccccc4-3)ccc21 +CN1c2ccccc2Oc2cc(-c3cc4[nH]c5ccncc5c4cn3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(-c4ccccn4)nc3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(C#N)c(C#N)c3C#N)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(C(=O)C(F)(F)F)cc3)ccc21 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2Oc3c(N(C)c2cc1)cccc3 +CN1c2ccccc2Oc2cc(-c3ccc4ccc5cccnc5c4n3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4cccnc4n3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4ncc5ccccc5c4c3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4nn[nH]c4c3)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc4[nH]c5ncccc5c34)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc4[nH]nnc34)ccc21 +CN1c2ccccc2Oc2cc(-c3cncc4c3[nH]c3ccncc34)ccc21 +CN1c2ccccc2Oc2cc(-c3cncc4cc[nH]c34)ccc21 +CN1c2ccccc2Oc2cc(-c3c[nH]c4ccncc34)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4ccccc4c4ccccc34)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4ccccc4o3)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc21 +CN1c2ccccc2Oc2cc(-c3nccc4c3[nH]c3ccccc34)ccc21 +CN1c2ccccc2Oc2cc(-n3cnc4nc5nc[nH]c5cc43)ccc21 +CN1c2ccccc2Oc2ccc(-c3c(C#N)cccc3C#N)cc21 +CN1c2ccccc2Oc2ccc(-c3c4ccoc4cc4ccoc34)cc21 +CN1c2ccccc2Oc2ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc21 +CN1c2ccccc2Oc2ccc(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cc21 +CN1c2ccccc2Oc2ccc(-c3cc4nc5ccoc5nc4[nH]3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc(C#N)c(C#N)c3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cc21 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2Oc3c(N(C)c2c1)cccc3 +CN1c2ccccc2Oc2ccc(-c3ccc4ccsc4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc4nn[nH]c4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3cccc4c3-c3ccccc3-s-4(=O)=O)cc21 +O=C1c2c(C(=O)N1)cccc2c1ccc2Oc3c(N(C)c2c1)cccc3 +CN1c2ccccc2Oc2ccc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc21 +CN1c2ccccc2Oc2ccc(-c3cnc4ncccc4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3cncc4c3[nH]c3ccncc34)cc21 +CN1c2ccccc2Oc2ccc(-c3nc4ccccc4o3)cc21 +CN1c2ccccc2Oc2ccc(-c3nccnc3-c3ccccc3)cc21 +CN1c2ccccc2Oc2ccc(-c3ncon3)cc21 +CN1c2ccccc2Oc2ccc(-n3ccc4nc5ccoc5nc43)cc21 +CN1c2ccccc2Oc2cccc(-c3(C)-c4ccccc4-c4ccccc4-3)c21 +CN1c2ccccc2Oc2cccc(-c3=cC(=O)c4ccccc4C3=O)c21 +CN1c2ccccc2Oc2cccc(-c3c4[nH]cnc4nc4nc[nH]c34)c21 +CN1c2ccccc2Oc2cccc(-c3cc4cc5occc5cc4o3)c21 +CN1c2ccccc2Oc2cccc(-c3cc4nc5ccoc5nc4[nH]3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc(-c4ccccn4)nc3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(c3)C(=O)c=cC4=O)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(cnc5ccccc54)c3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4ccc5cccnc5c4n3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4nn[nH]c4c3)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4ncc5ccccc5c34)c21 +CN1c2ccccc2Oc2cccc(-c3cnc4c(ccc5cccnc54)c3)c21 +CN1c2ccccc2Oc2cccc(-c3cnc4cccnc4c3)c21 +CN1c2ccccc2Oc2cccc(-c3nc4cc5ncoc5nc4o3)c21 +CN1c2ccccc2Oc2cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c21 +CN1c2ccccc2Oc2cccc(-c3ncc(C#N)cn3)c21 +CN1c2ccccc2Oc2cccc(-c3nccc4c3[nH]c3ccccc34)c21 +CN1c2ccccc2Oc2cccc(-n3ccc4cnccc43)c21 +CN1c2ccccc2Oc2cccc(-n3cnc4nc5nc[nH]c5cc43)c21 +Fc1c(c(c(c(F)c1N1c2c(CCc3c1cccc3)cccc2)F)F)F +Fc1c(F)c(F)c(-c2ccc3c(c2)c2ccccc2c2[nH]cnc32)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c(n2)sc2ncccc23)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c4c2CCCN4CCC3)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3ccoc3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3cc[nH]c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3oc4ccccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3[nH]c4cnccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c2oc2ncccc23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4ccccc4c4[nH]cnc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4nccnc4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4nc[nH]c4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4[nH]cnc4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3ccoc23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3ncc4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2ccn[nH]2)c(F)c1F +Fc1c(F)c(F)c(-c2cnc3sc4ccccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2cncc3c2[nH]c2ccccc23)c(F)c1F +Fc1c(F)c(F)c(-c2coc3cc4[nH]ccc4cc23)c(F)c1F +Fc1cc(-c2c3ccoc3cc3ccoc23)cc(F)c1F +Fc1cc(-c2ccc3sccc3c2)cc(F)c1F +Fc1cc(-c2ccc3[nH]nnc3c2)cc(F)c1F +Fc1cc(-c2cccc3[nH]c4cnccc4c23)cc(F)c1F +Fc1cc(-c2cccc3[nH]c4ncccc4c23)cc(F)c1F +Fc1cc(-c2cnc3ccccc3n2)cc(F)c1F +Fc1cc(-c2cnc3cccnc3c2)cc(F)c1F +Fc1cc(-c2csc3ccccc23)cc(F)c1F +Fc1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc(F)c1F +Fc1cc(-n2cnc3nc4nc[nH]c4nc32)cc(F)c1F +Fc1cc(-n2nnc3ccccc32)cc(F)c1F +Fc1ccc(-c2c3[nH]cnc3nc3nc[nH]c23)c(F)c1F +Fc1ccc(-c2cc3cc4occc4cc3o2)c(F)c1F +Fc1ccc(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c(F)c1F +Fc1ccc(-c2cccc3ncoc23)c(F)c1F +Fc1ccc(-c2cccnc2-c2ccccn2)c(F)c1F +Fc1ccc(-c2cncc3cc[nH]c23)c(F)c1F +Fc1ccc(-c2csc3ccccc23)c(F)c1F +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc5cc6cc[nH]c6cc5o4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc5nc6ccoc6nc5[nH]4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccc6c7ccccc7[nH]c6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccncc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(n4)oc4ccccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c6ccccc6c6[nH]cnc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5ncc6ccccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5oc6ccccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5oc6ncccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5[nH]c6ccncc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc(-c5cc6c7c(c5)CCCN7CCC6)c4)cc3)n2)cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5c4oc4ncccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5c6[nH]cnc6c6ccccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5ncc6ccccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5[nH]c6cnccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4csc5ccccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4c[nH]c5cc6occc6cc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4c[nH]c5nc6occc6nc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-n4c5ccccc5c5c6[nH]c7ccccc7c6ccc54)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c5ccoc5cc5ccoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c5ncoc5cc5ncoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5cc6cc[nH]c6cc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5ccccc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5ccccc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5nc6cc[nH]c6nc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c(c4)sc4ncccc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c(c4)[nH]c4[nH]c6ccccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c6ccccc6c6nc[nH]c6c5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5ncoc5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5c4[nH]c4ccncc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5cc[nH]c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5occc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5[nH]nnc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c[nH]c5nc6occc6nc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4nc5cc6scnc6cc5s4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4nccc5[nH]c6ccccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-n4c5ccccc5c5c6ccccc6[nH]c54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-n4c5ccccc5c5cnccc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3c4ccoc4cc4ccoc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3c4ncoc4cc4ncoc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4c5c(c3)CCCN5CCC4)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4nc5ccoc5nc4[nH]3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(c3)Oc3ccccc3O4)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(n3)sc3ccccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(n3)sc3ncccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c5ccccc5c5[nH]cnc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4ccoc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4[nH]nnc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4c5ccccc5c5nccnc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4scnc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccccc3N(c3ccccc3)c3ccccc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccnc4sc5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cnc4sc5ncccc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cn[nH]c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-n3ccc4ccccc43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cc5ccccc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cc5nc6ccoc6nc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5c(c4)c4ccccc4c4[nH]cnc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5c(c4)[nH]c4c5ccc5[nH]c6ccccc6c54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5ocnc5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5[nH]c6ccc7c8ccccc8[nH]c7c6c5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5c6ccccc6c6nccnc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5ccoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5occc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5[nH]c6ccc7c8ccccc8[nH]c7c6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccccc4-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccnc5sc6ncccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccnnc4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4coc5cc6ccoc6cc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4nccc5[nH]c6ccncc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-n4nnc5ccccc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3c4ncsc4cc4ncsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3cnccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c5ccccc5c5[nH]cnc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4ocnc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4[nH]c5cnccc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4c3sc3ncccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4ccsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4cnc5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4ncsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4sccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5ccncc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4[nH]ccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccnc4sc5ncccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cnc4c5ccccc5c5ccccc5c4n3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3coc4cc5[nH]ccc5cc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3nc4c5ccccc5c5ccccc5c4[nH]3)n2)cc1 +Fc1ccc(-n2ccc3cnccc32)c(F)c1F +N#Cc1cc(-c2c3[nH]ccc3cc3ccoc23)cc(C#N)c1C#N +N#Cc1cc(-c2cc(=O)c3ccccc3[nH]2)cc(C#N)c1C#N +N#Cc1cc(-c2cc3ccccc3o2)cc(C#N)c1C#N +N#Cc1cc(-c2ccc(F)c(F)c2F)cc(C#N)c1C#N +N#Cc1c(c(C#N)cc(c1)c1ccc2CCc3c(cccc3)Nc2c1)C#N +N#Cc1cc(-c2ccc3c(c2)oc2ccccc23)cc(C#N)c1C#N +N#Cc1cc(-c2ccc3c(cnc4ccccc43)c2)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3c4nc[nH]c4c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3c4[nH]cnc4c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3ocnc23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3sccc23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3[nH]ccc(=O)c23)cc(C#N)c1C#N +N#Cc1cc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)cc(C#N)c1C#N +N#Cc1cc(-c2cncc3[nH]c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2coc3cc4ccoc4cc23)cc(C#N)c1C#N +N#Cc1cc(-c2csc3ccccc23)cc(C#N)c1C#N +N#Cc1cc(-c2c[nH]c3nc4occc4nc23)cc(C#N)c1C#N +N#Cc1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc(C#N)c1C#N +N#Cc1cc(-n2ccc(=O)c3ccccc32)cc(C#N)c1C#N +N#Cc1cc(C#N)c(-c2cc3cc4cc[nH]c4cc3o2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cc3cc4occc4cc3o2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3c(n2)sc2ccccc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3ncoc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3oc4ncccc4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3sccc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3scnc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc(N(c3ccccc3)c3ccccc3)c2)c(C#N)c1 +N#Cc1cc(C#N)cc(C#N)c1c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1cc(C#N)c(-c2cccc3c4ccccc4c4nc[nH]c4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3ccoc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3ccsc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3oc4ccccc4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3occc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3[nH]ccc(=O)c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cnc3sc4ccccc4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2c[nH]c3ccccc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2nc3cc4scnc4cc3s2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2nccc3[nH]c4ccncc4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-n2nnc3ccccc32)c(C#N)c1 +N#Cc1cc(C#N)cc(-c2c3cc[nH]c3cc3occc23)c1 +N#Cc1cc(C#N)cc(-c2c3ncsc3cc3ncsc23)c1 +N#Cc1cc(C#N)cc(-c2cc3c(cn2)[nH]c2ccccc23)c1 +N#Cc1cc(C#N)cc(-c2cc3nc4cc[nH]c4nc3o2)c1 +N#Cc1cc(C#N)cc(-c2cc3[nH]c4ccccc4c3cn2)c1 +N#Cc1cc(C#N)cc(-c2ccc(N)cc2)c1 +N#Cc1cc(C#N)cc(-c2ccc3c(=O)c4ccccc4[nH]c3c2)c1 +N#Cc1cc(C#N)cc(-c2ccc3cnc4ccccc4c3c2)c1 +N#Cc1cc(C#N)cc(-c2ccc3[nH]nnc3c2)c1 +N#Cc1cc(C#N)cc(-c2cccc(N)c2)c1 +N#Cc1cc(C#N)cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3c4[nH]cnc4c4ccccc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3ccoc23)c1 +N#Cc1cc(C#N)cc(-c2cccc3cnc4ccccc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3ncoc23)c1 +N#Cc1cc(C#N)cc(-c2cccc3occc23)c1 +N#Cc1cc(C#N)cc(-c2cc[nH]n2)c1 +N#Cc1cc(C#N)cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +N#Cc1cc(C#N)cc(-c2cncc3c2[nH]c2ccncc23)c1 +N#Cc1cc(C#N)cc(-n2c3ccccc3c3cnccc32)c1 +N#Cc1ccc(-c2c3ccoc3cc3ccoc23)cc1C#N +N#Cc1ccc(-c2c3ncoc3cc3ncoc23)c(C#N)c1 +N#Cc1ccc(-c2c3[nH]ccc3cc3ccoc23)c(C#N)c1 +N#Cc1ccc(-c2c3[nH]ccc3cc3ccoc23)c(C#N)c1C#N +N#Cc1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)cc1 +N#Cc1ccc(-c2cc3cc4ccoc4cc3[nH]2)cc1C#N +N#Cc1ccc(-c2cc3cc4cc[nH]c4cc3o2)c(C#N)c1C#N +N#Cc1ccc(-c2cc3ccccc3o2)c(C#N)c1 +N#Cc1ccc(-c2cc3ccccc3[nH]2)cc1 +N#Cc1ccc(-c2cc3nc4ccoc4nc3[nH]2)c(C#N)c1C#N +N#Cc1ccc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cc3[nH]c4ccccc4c3cn2)cc1 +N#Cc1ccc(-c2ccc(F)c(F)c2F)cc1 +N#Cc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1C#N +N#Cc1ccc(-c2ccc(N)cc2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(=O)cc[nH]c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(=O)cc[nH]c3c2)cc1C#N +N#Cc1ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +N#Cc1ccc(-c2ccc3c(c2)oc2ccccc23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(c2)Oc2ccccc2O3)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(c2)oc2ncccc23)cc1 +N#Cc1ccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cc1 +N#Cc1ccc(-c2ccc3c(cnc4ccccc43)c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(cnc4ccccc43)c2)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(n2)oc2ccccc23)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(n2)sc2ccccc23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(n2)sc2ccccc23)cc1 +N#Cc1ccc(-c2ccc3c(n2)sc2ncccc23)c(C#N)c1 +N#Cc1ccc(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)cc1 +N#Cc1ccc(-c2ccc3cnc4ccccc4c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3oc4ccccc4c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3occc3c2)cc1 +N#Cc1ccc(-c2ccc3[nH]c4ccc5c6ccccc6[nH]c5c4c3c2)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)cc1C#N +N#Cc1ccc(-c2ccc3[nH]ccc3c2)c(C#N)c1C#N +N#Cc1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2)cc1C#N +N#Cc1ccc(-c2cccc(N)c2)c(C#N)c1C#N +N#Cc1ccc(-c2cccc(N)c2)cc1C#N +N#Cc1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)cc1C#N +N#Cc1ccc(-c2cccc3c(=O)cc[nH]c23)c(C#N)c1C#N +N#Cc1c(c(C#N)c(cc1)c1c2c(Sc3c(cccc3)N2)ccc1)C#N +N#Cc1ccc(cc1)c1c2c(ccc1)Nc1c(S2)cccc1 +N#Cc1ccc(-c2cccc3c2cnc2ccccc23)cc1 +N#Cc1ccc(-c2cccc3c2oc2ccccc23)c(C#N)c1 +N#Cc1ccc(-c2cccc3c2sc2ncccc23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2cnccc23)cc1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)cc1 +N#Cc1ccc(-c2cccc3c4nc[nH]c4c4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c4nc[nH]c4c4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3c4[nH]cnc4c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3cnc4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3ncc4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3ncoc23)cc1 +N#Cc1ccc(-c2cccc3oc4ncccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3oc4ncccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3ocnc23)cc1 +N#Cc1ccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3[nH]c4cnccc4c23)cc1 +N#Cc1ccc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)cc1C#N +N#Cc1ccc(-c2cccc3[nH]ccc23)cc1C#N +N#Cc1ccc(-c2cccc3[nH]nnc23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3[nH]nnc23)cc1C#N +N#Cc1ccc(-c2ccccc2N)c(C#N)c1 +N#Cc1ccc(-c2ccnc3sc4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2ccnnc2)c(C#N)c1 +N#Cc1ccc(-c2cncc3[nH]c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cn[nH]c2)c(C#N)c1 +N#Cc1ccc(-c2coc3cc4ccoc4cc23)cc1 +N#Cc1ccc(-c2coc3cc4[nH]ccc4cc23)c(C#N)c1C#N +N#Cc1ccc(-c2coc3ccccc23)cc1C#N +N#Cc1ccc(-c2c[nH]c3cc4occc4cc23)c(C#N)c1C#N +N#Cc1ccc(-c2c[nH]c3ccccc23)c(C#N)c1 +N#Cc1ccc(-c2c[nH]c3ccccc23)cc1C#N +N#Cc1ccc(-c2nc3cc4scnc4cc3s2)c(C#N)c1C#N +N#Cc1ccc(-c2nc3ccccc3c3ccccc23)c(C#N)c1 +N#Cc1ccc(-c2nc3ccccc3s2)c(C#N)c1 +N#Cc1ccc(-c2nc3ccccc3s2)c(C#N)c1C#N +N#Cc1ccc(-c2nc3ccccc3s2)cc1C#N +N#Cc1ccc(-c2nc3nc4nc[nH]c4nc3[nH]2)c(C#N)c1 +N#Cc1ccc(-c2nccc3c2[nH]c2ccccc23)c(C#N)c1 +N#Cc1ccc(-n2c3ccccc3c3c4ccccc4[nH]c32)cc1 +N#Cc1ccc(-n2c3ccccc3c3c4ccccc4[nH]c32)cc1C#N +N#Cc1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c(C#N)c1C#N +N#Cc1ccc(-n2c3ccccc3c3ccncc32)cc1C#N +N#Cc1ccc(-n2ccc(=O)c3ccccc32)cc1C#N +N#Cc1ccc(-n2ccc3cc4ccoc4cc32)cc1 +N#Cc1ccc(-n2ccc3cc4ccoc4cc32)cc1C#N +N#Cc1ccc(-n2cnc3c4ccccc4c4ccccc4c32)cc1C#N +N#Cc1cccc(c1)N1c2c(Sc3c1cccc3)cccc2 +N#Cc1cccc(-c2c3cc[nH]c3cc3occc23)c1 +N#Cc1cccc(-c2c3cc[nH]c3cc3occc23)c1C#N +N#Cc1cccc(-c2c3ncsc3cc3ncsc23)c1 +N#Cc1cccc(-c2cc3cc4ccoc4cc3[nH]2)c1C#N +N#Cc1cccc(-c2cc3cc4occc4cc3o2)c1C#N +N#Cc1cccc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c1 +N#Cc1cccc(-c2cc3[nH]c4ccncc4c3cn2)c1 +N#Cc1cccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1 +N#Cc1cccc(-c2ccc3c(=O)cc[nH]c3c2)c1C#N +N#Cc1cccc(-c2ccc3c(c2)c2ccccc2c2[nH]cnc32)c1C#N +N#Cc1c(C#N)c(ccc1)c1cc2CCc3c(cccc3)Nc2cc1 +N#Cc1cccc(-c2ccc3c(c2)oc2ncccc23)c1 +N#Cc1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +N#Cc1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1C#N +N#Cc1cccc(-c2ccc3nn[nH]c3c2)c1C#N +N#Cc1cccc(-c2ccc3occc3c2)c1 +N#Cc1cccc(-c2ccc3occc3c2)c1C#N +N#Cc1cccc(-c2ccc3[nH]nnc3c2)c1C#N +N#Cc1cccc(-c2cccc(N)c2)c1C#N +N#Cc1cccc(-c2cccc3c(=O)cc[nH]c23)c1 +N#Cc1cccc(c1)c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1cccc(c1)c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1c(C#N)c(ccc1)c1c2c(ccc1)Nc1c(S2)cccc1 +N#Cc1cccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c1 +N#Cc1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +N#Cc1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1C#N +N#Cc1cccc(-c2cccc3ccoc23)c1 +N#Cc1cccc(-c2cccc3ocnc23)c1 +N#Cc1cccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c1C#N +N#Cc1cccc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c1 +N#Cc1cccc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)c1C#N +N#Cc1cccc(-c2ccnc3sc4ccccc4c23)c1 +N#Cc1cccc(-c2ccnc3sc4ccccc4c23)c1C#N +N#Cc1cccc(-c2ccnc3sc4ncccc4c23)c1 +N#Cc1cccc(-c2ccnc3sc4ncccc4c23)c1C#N +N#Cc1cccc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1C#N +N#Cc1cccc(-c2cn[nH]c2)c1C#N +N#Cc1cccc(-c2c[nH]c3ccccc23)c1 +N#Cc1cccc(-c2nc3cc4scnc4cc3s2)c1 +N#Cc1cccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c1 +N#Cc1cccc(-n2ccc3ccccc32)c1C#N +N#Cc1cccc(C#N)c1-c1c2[nH]ccc2cc2ccoc12 +N#Cc1cccc(C#N)c1-c1cc2nc3cc[nH]c3nc2o1 +N#Cc1cccc(C#N)c1-c1ccc2c(c1)oc1ncccc12 +N#Cc1cccc(C#N)c1-c1ccc2ncc3ccccc3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2occc2c1 +N#Cc1cccc(C#N)c1-c1ccc2sc3ncccc3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3ccc4c5ccccc5[nH]c4c3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3ccncc3c2c1 +N#Cc1cccc(C#N)c1c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1cccc(C#N)c1-c1cccc2c3ccccc3c3nccnc3c12 +N#Cc1cccc(C#N)c1-c1cccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c12 +N#Cc1cccc(C#N)c1-c1cccc2[nH]ccc(=O)c12 +N#Cc1cccc(C#N)c1-c1ccccc1N(c1ccccc1)c1ccccc1 +N#Cc1cccc(C#N)c1-c1cn[nH]c1 +N#Cc1cccc(C#N)c1-c1nc2ccccc2s1 +N#Cc1cccc(C#N)c1-n1c2ccccc2c(=O)c2ccccc21 +N#Cc1cccc(C#N)c1-n1c2ccccc2c2c3ccccc3[nH]c21 +N#Cc1cccc(C#N)c1-n1c2ccccc2c2cnccc21 +N#Cc1cccc(C#N)c1-n1c2ccncc2c2cnccc21 +N#Cc1cccc(C#N)c1-n1ccc2nc3ccoc3nc21 +N#Cc1cccc(C#N)c1-n1cnc2nc3nc[nH]c3nc21 +N#Cc1ccccc1-c1c(-c2ccccc2)cc2c3c1CCCN3CCC2 +N#Cc1ccccc1-c1cc(F)c(F)c(F)c1 +N#Cc1ccccc1-c1cc2cc3cc[nH]c3cc2o1 +N#Cc1ccccc1-c1cc2[nH]c3ccncc3c2cn1 +N#Cc1ccccc1-c1ccc2c(c1)c1ccccc1c1[nH]cnc21 +N#Cc1ccccc1-c1ccc2scnc2c1 +N#Cc1ccccc1c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1ccccc1-c1cccc2c3ccccc3c3nc[nH]c3c12 +N#Cc1ccccc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +N#Cc1ccccc1-c1cccc2c3[nH]cnc3c3ccccc3c12 +N#Cc1ccccc1-c1cccc2ncc3ccccc3c12 +N#Cc1ccccc1-c1cccc2[nH]c3[nH]c4ccccc4c3c12 +N#Cc1ccccc1-c1cccc2[nH]nnc12 +N#Cc1ccccc1-c1cc[nH]n1 +N#Cc1ccccc1-c1coc2cc3[nH]ccc3cc12 +N#Cc1ccccc1-c1c[nH]c2cc3occc3cc12 +N#Cc1ccccc1-n1c2ccccc2c2cnccc21 +N#Cc1cnc(-c2cc3ccccc3o2)nc1 +N#Cc1cnc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)nc1 +c1(C#N)cnc(nc1)c1cc2c(Sc3c(cccc3)N2)cc1 +N#Cc1cnc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)nc1 +N#Cc1cnc(-c2ccc3c(c2)Oc2ccccc2O3)nc1 +N#Cc1cnc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)nc1 +N#Cc1cnc(-c2ccc3sc4ncccc4c3c2)nc1 +N#Cc1cnc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)nc1 +N#Cc1cnc(-c2ccc3[nH]nnc3c2)nc1 +N#Cc1cnc(-c2cccc3c2sc2ncccc23)nc1 +N#Cc1cnc(-c2cccc3c2[nH]c2cnccc23)nc1 +N#Cc1cnc(-c2cccc3c4ccccc4c4[nH]cnc4c23)nc1 +N#Cc1cnc(-c2cccc3c4nccnc4c4ccccc4c23)nc1 +N#Cc1cnc(-c2cccc3ccsc23)nc1 +N#Cc1cnc(-c2cccc3ncc4ccccc4c23)nc1 +N#Cc1cnc(-c2cccc3ncsc23)nc1 +N#Cc1cnc(-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)nc1 +N#Cc1cnc(-c2cnc3sc4ncccc4c3c2)nc1 +N#Cc1cnc(-c2c[nH]c3nc4occc4nc23)nc1 +N#Cc1cnc(-c2nc3ccccc3c3ccccc23)nc1 +N#Cc1cnc(-n2c3ccccc3c3ccncc32)nc1 +N#Cc1cnc(-n2ccc(=O)c3ccccc32)nc1 +N#Cc1cncnc1-c1cc2[nH]c3ccccc3c2cn1 +N#Cc1cncnc1-c1ccc2c(c1)Oc1ccccc1O2 +N#Cc1cncnc1-c1ccc2ncoc2c1 +N#Cc1cncnc1-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +N#Cc1cncnc1-c1cccc(N(c2ccccc2)c2ccccc2)c1 +c1(C#N)cncnc1c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1cncnc1-c1cccc2c1oc1ccccc12 +N#Cc1cncnc1-c1cccc2c1oc1ncccc12 +N#Cc1cncnc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +N#Cc1cncnc1-c1cccc2sccc12 +N#Cc1cncnc1-c1cccc2scnc12 +N#Cc1cncnc1-c1cccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c12 +N#Cc1cncnc1-c1cccc2[nH]c3ccncc3c12 +N#Cc1cncnc1-c1cccc2[nH]nnc12 +N#Cc1cncnc1-c1nc2c3ccccc3c3ccccc3c2[nH]1 +N#Cc1cncnc1-c1nc2ccccc2o1 +N#Cc1cncnc1-c1nccc2c1[nH]c1ccccc12 +N#Cc1cncnc1-c1nccc2[nH]c3ccncc3c12 +N#Cc1cncnc1-n1c2ccccc2c2ccc3[nH]c4ccccc4c3c21 +N#Cc1cncnc1-n1c2ccncc2c2cnccc21 +N#Cc1cncnc1-n1ccc2nc3ccoc3nc21 +Nc1ccc(-c2c3ncoc3nc3ocnc23)cc1 +Nc1ccc(-c2ccc3c(c2)-s(=O)(=O)-c2ccccc2-3)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc(N)cc1 +Nc1ccc(-c2ccc3ncccc3n2)cc1 +Nc1ccc(-c2ccc3[nH]nnc3c2)cc1 +Nc1ccc(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)cc1 +Nc1ccc(-c2cccc(C(=O)C(F)(F)F)c2)cc1 +Nc1ccc(-c2cccc3ocnc23)cc1 +Nc1ccc(-c2cccc3[nH]c4ncccc4c23)cc1 +Nc1ccc(-c2cnc3nccnc3n2)cc1 +Nc1ccc(-c2nc3ccccc3o2)cc1 +Nc1ccc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc1 +Nc1ccc(-n2c3ccncc3c3cnccc32)cc1 +Nc1ccc(-n2cnc3cc4nc[nH]c4cc32)cc1 +Nc1ccc(-n2cnc3nc4nc[nH]c4cc32)cc1 +Nc1cccc(-c2c(F)c(F)c(F)c(F)c2F)c1 +Nc1cccc(-c2c3ccoc3cc3ccoc23)c1 +Nc1cccc(-c2cc(=O)c3ccccc3[nH]2)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cccc(N)c1 +Nc1cccc(-c2ccc3c4c2Oc2ccccc2B4c2ccccc2O3)c1 +Nc1cccc(-c2ccc3cccnc3n2)c1 +Nc1cccc(-c2ccc3ncc4ccccc4c3c2)c1 +Nc1cccc(-c2ccc3ocnc3c2)c1 +Nc1cccc(-c2cccc(-c3ccccn3)n2)c1 +Nc1cccc(-c2cccc3sccc23)c1 +Nc1cccc(-c2ccon2)c1 +Nc1cccc(-c2cncc3cc[nH]c23)c1 +Nc1cccc(-c2coc3cc4ccoc4cc23)c1 +Nc1cccc(-c2nc3ccccc3o2)c1 +Nc1cccc(-n2ccc3nc4ccoc4nc32)c1 +Nc1ccccc1-c1c2[nH]cnc2nc2nc[nH]c12 +Nc1ccccc1-c1cc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)ccc1F +Nc1ccccc1-c1cc2c(cn1)[nH]c1ccccc12 +Nc1ccccc1-c1ccc(-c2ccccn2)nc1 +Nc1ccccc1-c1ccc(-c2cnccn2)cc1 +Nc1ccccc1-c1ccc2c(c1)B1c3ccccc3Oc3cccc(c31)O2 +Nc1ccccc1-c1ccc2c(c1)sc1ccccc12 +Nc1ccccc1-c1ccc2nccnc2c1 +Nc1ccccc1-c1ccc2sc3ccccc3c2c1 +Nc1ccccc1-c1ccc2[nH]c3cnccc3c2c1 +Nc1ccccc1-c1ccc2[nH]ccc(=O)c2c1 +Nc1ccccc1-c1cccc2nccnc12 +Nc1ccccc1-c1cccc2sc3ccccc3c12 +Nc1ccccc1-c1cccc2[nH]ccc(=O)c12 +Nc1ccccc1-c1ccccc1C(=O)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +Nc1ccccc1-c1cncc2[nH]c3ccccc3c12 +Nc1ccccc1-c1nc2cc3ncoc3nc2o1 +Nc1ccccc1-c1nc2ccccc2o1 +Nc1ccccc1-n1c2ccccc2c2ccncc21 +Nc1ccccc1-n1ccc2cnccc21 +O=C(c1ccc(-c2c(-c3ccccc3)cc3c4c2CCCN4CCC3)cc1)C(F)(F)F +O=C(c1ccc(-c2c3ccoc3cc3ccoc23)cc1)C(F)(F)F +O=C(c1ccc(-c2c3cc[nH]c3cc3occc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cc3[nH]c4ccccc4c3cn2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2cc3[nH]c4ccncc4c3cn2)cc1)C(F)(F)F +O=C(c1ccc(-c2ccc3c(=O)cc[nH]c3c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(cc1)c1cc2c(Sc3c(cccc3)N2)cc1)C(F)(F)F +O=C(c1ccc(-c2ccc3c(c2)c2ccccc2c2nccnc32)cc1)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +O=C(c1ccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2ccc3c(n2)sc2ccccc23)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2ccc3oc4ccccc4c3c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c(=O)cc[nH]c23)cc1)C(F)(F)F +O=C(c1ccc(cc1)c1c2CCc3c(cccc3)Nc2ccc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c2sc2ncccc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3ccoc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3oc4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3[nH]c4cnccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2ccnc3oc4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2ccnnc2)cc1)C(F)(F)F +O=C(c1ccc(-c2cnc3oc4ccccc4c3c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cnc3sc4ccccc4c3c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cncc3[nH]c4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2cn[nH]c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2c[nH]c(=O)[nH]2)cc1)C(F)(F)F +O=C(c1ccc(-c2c[nH]c3ccccc3c2=O)cc1)C(F)(F)F +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2c3ncsc3cc3ncsc23)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3c2cnc2ccccc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3cc[nH]c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3cnc4ccccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3nn[nH]c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3sc4ncccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3[nH]c4cnccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2coc3cc4ccoc4cc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2coc3ccccc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2c[nH]c3nc4occc4nc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2nc3ccccc3o2)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-n2ccc3nc4ccoc4nc32)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)N1c2c(Sc3c1cccc3)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)N1c2c(CCc3c1cccc3)cccc2 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3c(cn2)[nH]c2ccccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3ccccc3[nH]2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3nc4ccoc4nc3[nH]2)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)Oc2ccccc2O3)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2cnccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(n2)oc2ccccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3ccsc3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3occc3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c2oc2ncccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c4ccccc4c4nccnc4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3cc[nH]c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3ncsc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3nn[nH]c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3[nH]nnc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2c[nH]c3nc4occc4nc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2nc3ccccc3s2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2nccc3[nH]c4ccccc4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-n2c3ccccc3c3cnccc32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-n2ccc3cc4ccoc4cc32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c2cc[nH]c2cc2occc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c2ncoc2cc2ncoc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc(-c2cc3c4c(c2)CCCN4CCC3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1ccc2c(Sc3c(cccc3)N2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)ncc1ccccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)oc1ncccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)sc1ncccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)[nH]c1ccc3c4ccccc4[nH]c3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(n1)oc1ccccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c3ccccc3c3nc[nH]c3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2cnc3ccccc3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2ncoc2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cccc2c3nccnc3c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cccc2ccoc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccccc1N(c1ccccc1)c1ccccc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccnnc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cnc2oc3ccccc3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cncc2[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c[nH]c2cc3occc3cc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1nccc2[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1nccc2[nH]c3ccncc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1c2ccccc2c2c3[nH]c4ccccc4c3ccc21 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1c2ccccc2c2cnccc21 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1ccc2ccccc21 +O=C(c1ccc(-c2nc3ccccc3c3ccccc23)cc1)C(F)(F)F +O=C(c1ccc(-c2nccc3[nH]c4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)cc1)C(F)(F)F +O=C(c1ccc(-n2nnc3ccccc32)cc1)C(F)(F)F +O=C(c1cccc(-c2c3ncoc3cc3ncoc23)c1)C(F)(F)F +O=C(c1cccc(-c2c3ncsc3cc3ncsc23)c1)C(F)(F)F +O=C(c1cccc(-c2cc(=O)c3ccccc3[nH]2)c1)C(F)(F)F +O=C(c1cccc(-c2cc3cc4cc[nH]c4cc3o2)c1)C(F)(F)F +O=C(c1cccc(-c2cc3[nH]c4ccncc4c3cn2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cc2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3c(c2)Oc2ccccc2O3)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3c4c2CCCN4CCC3)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3ncc4ccccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3oc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3sc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3c(=O)cc[nH]c23)c1)C(F)(F)F +O=C(c1cccc(c1)c1c2c(CCc3c(cccc3)N2)ccc1)C(F)(F)F +O=C(c1cccc(-c2cccc3ccsc23)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3nn[nH]c23)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3oc4ncccc4c23)c1)C(F)(F)F +O=C(c1cccc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)c1)C(F)(F)F +O=C(c1cccc(-c2cnc3sc4ccccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2cnc3sc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2coc3cc4[nH]ccc4cc23)c1)C(F)(F)F +O=C(c1cccc(-c2csc3ccccc23)c1)C(F)(F)F +O=C(c1cccc(-c2c[nH]c3ccccc23)c1)C(F)(F)F +O=C(c1cccc(-c2c[nH]c3nc4occc4nc23)c1)C(F)(F)F +O=C(c1cccc(-c2nc3c4ccccc4c4ccccc4c3[nH]2)c1)C(F)(F)F +O=C(c1cccc(-n2c3ccccc3c(=O)c3ccccc32)c1)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)N3c4c(CCc5c3cccc5)cccc4)cc2)ccccc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cc5c(cn4)[nH]c4ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)ncc4ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)Oc4ccccc4O5)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)[nH]c4[nH]c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5ncoc5c4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5oc6ccccc6c5c4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4sc4ncccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4[nH]c4ccncc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c6ccccc6c6[nH]cnc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c6nccnc6c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5ccsc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5cnc6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5sc6ncccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5scnc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5[nH]c6ccccc6c(=O)c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cc[nH]n4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cncc5[nH]c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4coc5cc6[nH]ccc6cc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4coc5ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-n4c5ccccc5c5ccncc54)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-n4ccc(=O)c5ccccc54)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c(-c3ccccc3)cc3c4c2CCCN4CCC3)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c3ncsc3cc3ncsc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc(F)c(F)c2F)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(c2)c2ccccc2c2nccnc32)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(c2)oc2ncccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(n2)sc2ncccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3nn[nH]c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3[nH]c4ccncc4c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3[nH]nnc3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3c4[nH]cnc4c4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3cnc4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3sc4ncccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccnc3oc4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cn[nH]c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2coc3cc4[nH]ccc4cc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c[nH]c(=O)[nH]2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2nc3c4ccccc4c4ccccc4c3[nH]2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2nc3cc4ocnc4cc3o2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-n2ccc3cc4ccoc4cc32)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cc2c3ccccc3[nH]c2c2c1[nH]c1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2c(=O)cc[nH]c2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2c(n1)sc1ncccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2occc2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2sc3ncccc3c2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2[nH]ccc2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc(N(c2ccccc2)c2ccccc2)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2c3c(Sc4c(cccc4)N3)ccc2)ccccc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1cnc1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1Oc1ccccc1O2 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1oc1ncccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c3[nH]cnc3c3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2cnc3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2scnc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2[nH]c3cnccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccccc1-c1cc2c3c(c1)CCCN3CCC2 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cnc2c3ccccc3c3ccccc3c2n1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cncc2c1[nH]c1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1coc2cc3ccoc3cc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1coc2ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1c[nH]c2ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1nc2cc3ocnc3cc2o1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1nc2cc3scnc3cc2s1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-n1ccc2cc3ccoc3cc21 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-n1cnc2c3ccccc3c3ccccc3c21 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4cc5cc[nH]c5cc4o3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4cc5occc5cc4o3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3nccnc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)ncc3ccccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3ccncc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4[nH]ccc4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3ncc3ccccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3ccncc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3cnccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3[nH]c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c5nccnc5c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4ccsc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4nn[nH]c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4ocnc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5ccccc5c(=O)c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5cnccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccnn3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccnc4oc5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccn[nH]3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cnc4sc5ccccc5c4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cnc4sc5ncccc5c4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3coc4cc5[nH]ccc5cc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3c[nH]c(=O)[nH]3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3nccc4[nH]c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c(=O)c4ccccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c4cnccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccncc4c4cnccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3ccc(=O)c4ccccc43)n2)cc1 +O=C(c1ccccc1-c1c(-c2ccccc2)cc2c3c1CCCN3CCC2)C(F)(F)F +O=C(c1ccccc1-c1cc(=O)c2ccccc2[nH]1)C(F)(F)F +O=C(c1ccccc1-c1cc2nc3cc[nH]c3nc2o1)C(F)(F)F +O=C(c1ccccc1c1cc2c(Sc3c(cccc3)N2)cc1)C(F)(F)F +O=C(c1ccccc1c1cc2CCc3c(cccc3)Nc2cc1)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)oc1ncccc12)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccccc3c21)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1ccc2occc2c1)C(F)(F)F +O=C(c1ccccc1-c1cccc2c(=O)cc[nH]c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2c1[nH]c1c2ccc2[nH]c3ccccc3c21)C(F)(F)F +O=C(c1ccccc1-c1cccc2c3nccnc3c3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2ccoc12)C(F)(F)F +O=C(c1ccccc1-c1cccc2oc3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2[nH]c3ccc4c5ccccc5[nH]c4c3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2[nH]c3ccncc3c12)C(F)(F)F +O=C(c1ccccc1-c1ccccc1N(c1ccccc1)c1ccccc1)C(F)(F)F +O=C(c1ccccc1-c1coc2nc3[nH]ccc3nc12)C(F)(F)F +O=C(c1ccccc1-c1c[nH]c2cc3occc3cc12)C(F)(F)F +O=C(c1ccccc1-c1c[nH]c2ccccc2c1=O)C(F)(F)F +O=C(c1ccccc1-c1nc2c3ccccc3c3ccccc3c2[nH]1)C(F)(F)F +O=C(c1ccccc1-c1nccc2[nH]c3ccncc3c12)C(F)(F)F +O=C(c1ccccc1-n1c2ccccc2c(=O)c2ccccc21)C(F)(F)F +O=C(c1ccccc1-n1ccc(=O)c2ccccc21)C(F)(F)F +O=C(c1ccccc1-n1cnc2nc3nc[nH]c3nc21)C(F)(F)F +O=c1c(-c2c3[nH]ccc3cc3ccoc23)c[nH]c2ccccc12 +O=c1c(-c2c3[nH]cnc3nc3nc[nH]c23)c[nH]c2ccccc12 +O=c1c(-c2cc(F)c(F)c(F)c2)c[nH]c2ccccc12 +O=c1c(-c2cc3c4c(c2)CCCN4CCC3)c[nH]c2ccccc12 +O=c1c(-c2cc3ccccc3o2)c[nH]c2ccccc12 +O=c1c(-c2cc3ccccc3s2)c[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]cc1c1cc2CCc3c(cccc3)Nc2cc1 +O=c1c(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c[nH]c2ccccc12 +O=c1c(-c2ccc3c(c2)[nH]c2ncccc23)c[nH]c2ccccc12 +O=c1c(-c2ccc3c4c2CCCN4CCC3)c[nH]c2ccccc12 +O=c1c(-c2ccc3cc[nH]c3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3oc4ccccc4c3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3sccc3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c[nH]c2ccccc12 +O=c1c(-c2cccc(-c3cnccn3)c2)c[nH]c2ccccc12 +O=c1c(-c2cccc3c(=O)cc[nH]c23)c[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]cc1c1c2c(CCc3c(cccc3)N2)ccc1 +O=c1c(-c2cccc3c2ncc2ccccc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2Oc2ccccc2O3)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2sc2ncccc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c[nH]c2ccccc12 +O=c1c(-c2cccc3ccoc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3cnc4ccccc4c23)c[nH]c2ccccc12 +O=c1c(-c2ccnc(-c3ccccn3)c2)c[nH]c2ccccc12 +O=c1c(-c2ccnc3ncccc23)c[nH]c2ccccc12 +O=c1c(-c2ccnc3[nH]c4ccccc4c23)c[nH]c2ccccc12 +O=c1c(-c2ccno2)c[nH]c2ccccc12 +O=c1c(-c2cnc3cccnc3c2)c[nH]c2ccccc12 +O=c1c(-c2c[nH]c3ccccc23)c[nH]c2ccccc12 +O=c1c(-c2nc3cc4scnc4cc3s2)c[nH]c2ccccc12 +O=c1c(-c2nc3ccccc3s2)c[nH]c2ccccc12 +O=c1c(-c2nc3nc4nc[nH]c4cc3[nH]2)c[nH]c2ccccc12 +O=c1c(-c2nccc3[nH]c4ccncc4c23)c[nH]c2ccccc12 +O=c1c(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c[nH]c2ccccc12 +O=c1c(-n2c3ccncc3c3cnccc32)c[nH]c2ccccc12 +O=c1c(-n2ccc3cnccc32)c[nH]c2ccccc12 +O=c1c(-n2cc[nH]c2=O)c[nH]c2ccccc12 +O=c1c(-n2cnc3nc4nc[nH]c4nc32)c[nH]c2ccccc12 +O=C1c2c(C(=O)N1c1c3c(cc4c1cco4)[nH]cc3)cccc2 +O=C1c2c(C(=O)N1c1ncc3c4c(cccc4)[nH]c3c1)cccc2 +O=C1c2c(C(=O)N1c1nc3oc4c(c3cc1)cccc4)cccc2 +O=C1c2c(C(=O)N1c1ccc3c(c4c5c(cccc5)[nH]c4[nH]3)c1)cccc2 +O=C1c2c(C(=O)N1c1c3c4c(cccc4)cnc3ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3c(oc4ncccc34)ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3c(ccc1)[nH]c1c3ccnc1)cccc2 +O=C1c2c(C(=O)N1c1nc3c4c(c5c(c3nc1)cccc5)cccc4)cccc2 +O=C1c2c(C(=O)N1c1c3c4c(cccc4)[nH]c3cnc1)cccc2 +O=C1c2c(C(=O)N1n1c3c(c(=O)c4c1cccc4)cccc3)cccc2 +O=C1c2c(C(=O)N1n1c3c(c4c1ccnc4)cncc3)cccc2 +O=c1c2ccccc2n(-c2c3ccoc3cc3ccoc23)c2ccccc12 +O=c1c2ccccc2n(-c2cc(F)ccc2-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3c(c2)B2c4ccccc4Oc4cccc(c42)O3)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3ccsc3c2)c2ccccc12 +O=c1c2ccccc2n(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)c2ccccc12 +O=c1c2ccccc2n(-c2cccc3c2[nH]c2ncccc23)c2ccccc12 +O=c1c2ccccc2n(-c2ccnc3c2ccc2cccnc23)c2ccccc12 +O=c1c2ccccc2n(-c2cncc3cc[nH]c23)c2ccccc12 +O=c1c2ccccc2n(-c2cncc3[nH]c4ccccc4c23)c2ccccc12 +O=c1c2ccccc2n(-c2c[nH]c3ccncc23)c2ccccc12 +O=c1c2ccccc2n(-c2nccs2)c2ccccc12 +O=c1c2ccccc2n(-n2c3ccccc3c3cccnc32)c2ccccc12 +O=c1c2ccccc2n(-n2c3ccccc3c3ccncc32)c2ccccc12 +O=c1c2ccccc2n(-n2cnc3cc4nc[nH]c4cc32)c2ccccc12 +O=c1c2ccccc2[nH]c2c(-c3c(F)c(F)c(F)c(F)c3F)cccc12 +O=c1c2ccccc2[nH]c2c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cc4nc5ccoc5nc4[nH]3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc(-c4ccccn4)n3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc4c3[nH]c3cnccc34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3ccnc(-c4ccccn4)c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cnc4[nH]c5ccccc5c4c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cncs3)cccc12 +O=c1c2ccccc2[nH]c2c(-n3nnc4ccccc43)cccc12 +O=c1c2ccccc2[nH]c2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cc4cccnc4c4ncccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc(-c4cnccn4)cc3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(cnc5ccccc54)c3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cccc4ocnc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3csc4ccccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4cc5ncoc5nc4o3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4ccccc4o3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nccs3)ccc12 +O=c1c2ccccc2[nH]c2cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +O=c1c2ccccc2[nH]c2ccc(-c3c4ccoc4cc4ccoc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cc(F)ccc3-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cc4c(cn3)[nH]c3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc(-c4ccccn4)nc3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4ccsc4c3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4[nH]nnc4c3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4c(=O)cc[nH]c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4c3ncc3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4ccsc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4ncc5ccccc5c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccnc4c3ccc3cccnc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccnc4[nH]c5ccccc5c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cnc(-c4ccccc4)cn3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3nc4nc5ocnc5nc4o3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3nccc4c3[nH]c3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-n3ccc4cnccc43)cc12 +O=c1c2ccccc2[nH]c2cccc(-c3cc4cccnc4c4ncccc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4ccsc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4ncoc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4nn[nH]c4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4sc5ccccc5c4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cccc4c3-c3ccccc3-s-4(=O)=O)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cccc4ncc5ccccc5c34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccnc4cccnc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cnc4c(ccc5cccnc54)c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cnc4ncccc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cncs3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3nccc4[nH]ccc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ncno3)c12 +O=c1c2ccccc2[nH]c2cccc(-n3c4ccccc4c4ccncc43)c12 +O=C1c2c(C(=O)C(=C1)N1c3c(Sc4c1cccc4)cccc3)cccc2 +O=C1c=c(-c2c3ccoc3cc3ccoc23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(cc3c1cco3)[nH]cc2 +O=C1C=C(C(=O)N1)c1c2c(ocn2)cc2ncoc12 +O=C1C=C(C(=O)N1)c1cc(=O)c2c(cccc2)[nH]1 +O=C1c=c(-c2cc3c(cn2)[nH]c2ccccc23)C(=O)c2ccccc21 +O=C1c=c(-c2cc3cc4occc4cc3o2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1oc2c(c1)cccc2 +O=C1C=C(C(=O)N1)c1ncc2c(c1)[nH]c1c2cncc1 +O=C1C=C(C(=O)N1)c1ccc(N(c2ccccc2)c2ccccc2)cc1 +O=C1C=C(C(=O)N1)c1ccc2CCc3c(cccc3)Nc2c1 +O=C1c2c(C(=O)C(=C1)c1ccc3CCc4c(cccc4)Nc3c1)cccc2 +O=C1c2c(C(=O)C(=C1)c1ccc3c(Sc4c(cccc4)N3)c1)cccc2 +O=C1C=C(C(=O)N1)c1ccc2c(oc3ncccc23)c1 +O=C1C=C(C(=O)N1)c1cc2c(c3c4c(c5c(cccc5)[nH]4)ccc3[nH]2)cc1 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]c1c2cncc1 +O=C1c=c(-c2ccc3c4c2CCCN4CCC3)C(=O)c2ccccc21 +O=C1c=c(-c2ccc3c4ccccc4c4nccnc4c3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c3c(c4c(nc[nH]4)c2c1)cccc3 +O=C1C=C(C(=O)N1)c1ccc2c(scc2)c1 +O=C1c=c(-c2ccc3ccsc3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]cc2 +O=C1c=c(-c2ccc3ncsc3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]nn2 +O=C1C=C(C(=O)N1)c1cc2c(occ2)cc1 +O=C1c=c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)C(=O)c2ccccc21 +O=C1c=c(-c2ccc3[nH]nnc3c2)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3c2cnc2ccccc23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(c3c4c(cccc4)[nH]c3[nH]2)ccc1 +O=C1c=c(-c2cccc3c4ccccc4c4nc[nH]c4c23)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3c4ccccc4c4[nH]cnc4c23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(nn[nH]2)ccc1 +O=C1c=c(-c2cccc3ocnc23)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c(c2cc3c4c(CCCN4CCC3)c2)cccc1 +O=C1c=c(-c2cnc3sc4ccccc4c3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c3c(cccc3)[nH]c2cnc1 +O=C1c=c(-c2c[nH]c(=O)[nH]2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(cccc2)[nH]c1 +O=C1c=c(-c2nc3cc4ocnc4cc3o2)C(=O)c2ccccc21 +O=C1c=c(-n2c3ccccc3c(=O)c3ccccc32)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)n1c2c(c3c1ccnc3)cccc2 +O=C1C=C(C(=O)N1)n1c2c(nc1)c1c(c3c2cccc3)cccc1 +O=C1C=CC(=O)N1c1c2c(c3c(c4c(cccc4)[nH]3)c1)c1c(cccc1)[nH]2 +O=C1C=CC(=O)N1c1sc2c(c1)cccc2 +O=C1C=CC(=O)N1c1cc2c(cccc2)[nH]1 +O=C1C=CC(=O)N1c1oc2c(nc3c(n2)[nH]cc3)c1 +O=C1C=CC(=O)N1c1c2c3c(cccc3)[nH]c2c2c(c1)[nH]c1c2cccc1 +O=C1C=CC(=O)N1c1ncc2c(c1)[nH]c1c2cncc1 +O=C1C=CC(=O)N1c1ccc(c2cc3c4c(CCCN4CCC3)c2)cc1 +O=C1C=CC(=O)N1c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1C=CC(=O)N1c1cc2c(c3c4c(cccc4)[nH]c3[nH]2)cc1 +O=C1C=CC(=O)N1c1ccc2c3c(c4c(c2c1)nccn4)cccc3 +O=C1C=CC(=O)N1c1cc2c(occ2)cc1 +O=C1C=CC(=O)N1c1cc2ncsc2cc1 +O=C1C=CC(=O)N1c1c2ncc3c(c2ccc1)cccc3 +O=C1C=CC(=O)N1c1c2c(c3c(c4c(cc3)[nH]c3c4cccc3)[nH]2)ccc1 +O=C1C=CC(=O)N1c1c2c(nco2)ccc1 +O=C1C=CC(=O)N1c1c2c3c(cccc3)[nH]c2cnc1 +O=C1C=CC(=O)N1c1c2c(oc1)cc1c(occ1)c2 +O=C1C=CC(=O)N1c1c2c(oc1)cccc2 +O=C1C=CC(=O)N1c1c2c(cc3c(c2)cco3)[nH]c1 +O=C1C=CC(=O)N1c1c2c(c3c(n1)cccc3)cccc2 +O=C1C=CC(=O)N1n1c2c(c3c1ccnc3)cccc2 +O=C1C=CC(=O)N1n1c2c(nc3c(occ3)n2)cc1 +O=C1C=CC(=O)N1n1c2c(nn1)cccc2 +O=C1c2c(C(=O)C=C1)cccc2N1c2c(CCc3c1cccc3)cccc2 +O=C1c=cC(=O)c2c1cccc2-c1c2ncoc2cc2ncoc12 +O=C1c=cC(=O)c2c1cccc2-c1c2[nH]ccc2cc2ccoc12 +O=C1c=cC(=O)c2c1cccc2-c1cc2nc3ccoc3nc2[nH]1 +O=C1c=cC(=O)c2c1cccc2-c1ccc(F)c(F)c1F +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2c(c1)ncc1ccccc12 +O=C1c=cC(=O)c2c1cccc2-c1ccc2c(n1)sc1ncccc12 +O=C1c=cC(=O)c2c1cccc2-c1ccc2cnc3ccccc3c2c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2ncc3ccccc3c2c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +O=C1c2c(C(=O)C=C1)cccc2c1c2c(Sc3c(cccc3)N2)ccc1 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c1[nH]c1c2ccc2[nH]c3ccccc3c21 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c1[nH]c1cnccc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c3ccccc3c3nccnc3c12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2ccoc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2occc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2[nH]c3ccccc3c(=O)c12 +O=C1c=cC(=O)c2c1cccc2-c1ccccc1N(c1ccccc1)c1ccccc1 +O=C1c=cC(=O)c2c1cccc2-c1nc2c3ccccc3c3ccccc3c2[nH]1 +O=C1c=cC(=O)c2c1cccc2-c1nccc2[nH]c3ccncc3c12 +O=C1c=cC(=O)c2c1cccc2-n1c2ccncc2c2cnccc21 +O=C1c=cC(=O)c2c1cccc2-n1ccc(=O)c2ccccc21 +O=C1c=cC(=O)c2cc(-c3cc4cc5ccoc5cc4[nH]3)ccc21 +O=C1c=cC(=O)c2cc(-c3cc4cc5occc5cc4o3)ccc21 +O=C1c=cC(=O)c2cc(-c3cc4nc5cc[nH]c5nc4o3)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(c3)Oc3ccccc3O4)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(c3)sc3ncccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(n3)sc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4[nH]ccc(=O)c4c3)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3cnc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3ncc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3oc3ncccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3[nH]c3ccncc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5ccccc5c(=O)c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5ccncc5c34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccccc3-c3cc4c5c(c3)CCCN5CCC4)ccc21 +O=C1c=cC(=O)c2cc(-c3cnc4sc5ccccc5c4c3)ccc21 +O=C1c=cC(=O)c2cc(-n3cc[nH]c3=O)ccc21 +O=C1c=cC(=O)c2cc(-n3nnc4ccccc43)ccc21 +O=c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)[nH]c2ccccc12 +O=c1cc(-c2cc3cccnc3c3ncccc23)[nH]c2ccccc12 +O=c1cc(-c2cc3[nH]c4ccncc4c3cn2)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)-s(=O)(=O)-c2ccccc2-3)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)c2ccccc2c2nccnc32)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]c(c1)c1cc2CCc3c(cccc3)Nc2cc1 +O=c1cc(-c2ccc3c(n2)sc2ccccc23)[nH]c2ccccc12 +O=c1cc(-c2ccc3c4c2CCCN4CCC3)[nH]c2ccccc12 +O=c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3cc[nH]c3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3scnc3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3[nH]c4ccncc4c3c2)[nH]c2ccccc12 +O=c1cc(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4ccccc4c4nccnc4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4ccccc4c4nc[nH]c4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4nccnc4c4ccccc4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3[nH]c4ccccc4c(=O)c23)[nH]c2ccccc12 +O=c1cc(-c2ccnc3c2ccc2cccnc23)[nH]c2ccccc12 +O=c1cc(-c2ccnc3cccnc23)[nH]c2ccccc12 +O=c1cc(-c2ccon2)[nH]c2ccccc12 +O=c1cc(-c2cc[nH]n2)[nH]c2ccccc12 +O=c1cc(-c2cnc3cccnc3c2)[nH]c2ccccc12 +O=c1cc(-c2c[nH]c3ccncc23)[nH]c2ccccc12 +O=c1cc(-c2nc3nc4ocnc4nc3o2)[nH]c2ccccc12 +O=c1cc(-n2c3ccccc3c3ccncc32)[nH]c2ccccc12 +O=c1cc(-n2ccc(=O)c3ccccc32)[nH]c2ccccc12 +O=c1cc(-n2cnc3nc4nc[nH]c4nc32)[nH]c2ccccc12 +O=C1c2c(C(=O)N1)cccc2c1ncc2c(c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)cccc2c1c(F)c(c(F)cc1)F +O=C1c2c(C(=O)N1)cccc2c1ccc2c(sc3ncccc23)c1 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c1)[nH]c1c2ccc2c1c1c(cccc1)[nH]2 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c(=O)c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)cccc2c1cccc(N(c2ccccc2)c2ccccc2)c1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)Nc1c(S2)cccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(c3c(c4c2nccn4)cccc3)ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c3nc[nH]c3c3c(c2ccc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1c2ncsc2ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)[nH]c1c2cncc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(=O)cc[nH]c2ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c3c(sc2ncc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1nc2c3c(c4c(c2nc1)cccc4)cccc3 +O=C1c2c(C(=O)N1)cccc2c1cnc2c(c3c(nccc3)s2)c1 +O=C1c2c(C(=O)N1)cccc2c1oc2c(n1)cc1c(nco1)c2 +O=C1c2c(C(=O)N1)cccc2n1c2c(c(=O)c3c1cccc3)cccc2 +O=C1c2c(C(=O)N1)cccc2n1c2c(c3c1c1c(cc3)[nH]c3c1cccc3)cccc2 +O=C1c2c(C(=O)N1)cccc2n1c2c(nc1)c1c(c3c2cccc3)cccc1 +O=C1c2c(C(=O)N1)cccc2n1c2c(nc1)nc1nc[nH]c1n2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc3c(c2)cco3)[nH]1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c3c(cccc3)[nH]c2c2c(c1)[nH]c1c2cccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(oc3ncccc23)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)[nH]c1c2ccc2c1c1c(cccc1)[nH]2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(c3c4c(c5c(cccc5)[nH]4)ccc3[nH]2)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)cnc1c2cccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2ncoc2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(occ2)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c(=O)c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc1)[nH]cc2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c(=O)c3c(cccc3)[nH]2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(Sc3c(cccc3)N2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(nco2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccc1)[nH]c1c2c2c(cccc2)[nH]1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccnnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c3c(cccc3)[nH]2)cnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c3c(cccc3)[nH]c2cnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(oc1)cc1c(cc[nH]1)c2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(cc3c(c2)cco3)[nH]c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccn1)[nH]c1c2cncc1 +O=C1c2c(C(=O)N1)ccc(c2)n1c2c(c3c(cccc3)[nH]2)c2c1cccc2 +O=c1ccn(-c2c3ncsc3cc3ncsc23)c2ccccc12 +O=c1ccn(-c2cc3ccccc3o2)c2ccccc12 +O=c1ccn(-c2cc3cccnc3c3ncccc23)c2ccccc12 +O=c1ccn(-c2cc3[nH]ccc3cn2)c2ccccc12 +O=c1ccn(-c2ccc(F)c(F)c2F)c2ccccc12 +O=c1ccn(-c2ccc3c(c2)-c2ccccc2-s-3(=O)=O)c2ccccc12 +O=c1ccn(-c2ccc3c(c2)B2c4ccccc4Oc4cccc(c42)O3)c2ccccc12 +O=c1c2c(n(cc1)c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +O=c1ccn(-c2ccc3c(c2)[nH]c2ncccc23)c2ccccc12 +O=c1ccn(-c2ccc3[nH]ccc3c2)c2ccccc12 +O=c1ccn(-c2cccc3ccsc23)c2ccccc12 +O=c1ccn(-c2cccc3cnc4ccccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3oc4ccccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3oc4ncccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3ocnc23)c2ccccc12 +O=c1ccn(-c2cccc3scnc23)c2ccccc12 +O=c1ccn(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c2ccccc12 +O=c1ccn(-c2cccc3[nH]c4ccncc4c23)c2ccccc12 +O=c1ccn(-c2ccno2)c2ccccc12 +O=c1ccn(-c2cnc3sc4ncccc4c3c2)c2ccccc12 +O=c1ccn(-c2cncc(-c3ccccc3)n2)c2ccccc12 +O=c1ccn(-c2cncc3[nH]c4ccccc4c23)c2ccccc12 +O=c1ccn(-c2c[nH]c3cc4occc4cc23)c2ccccc12 +O=c1ccn(-c2c[nH]c3ccncc23)c2ccccc12 +O=c1cc[nH]c2c(-c3c4ccoc4cc4ccoc34)cccc12 +O=c1cc[nH]c2c(-c3c4[nH]ccc4cc4ccoc34)cccc12 +O=c1cc[nH]c2c(-c3cc4ccccc4o3)cccc12 +O=c1cc[nH]c2c(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc12 +O=c1cc[nH]c2c(-c3ccc(F)c(F)c3F)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)ncc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)oc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4ccsc4c3)cccc12 +O=c1cc[nH]c2c(-c3ccc4sccc4c3)cccc12 +O=c1cc[nH]c2c(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)cccc12 +O=c1cc[nH]c2c(-c3cccc4c3oc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3cccc4ncoc34)cccc12 +O=c1cc[nH]c2c(-c3cccc4nn[nH]c34)cccc12 +O=c1cc[nH]c2c(-c3cccc4oc5ccccc5c34)cccc12 +O=c1cc[nH]c2c(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)cccc12 +O=c1cc[nH]c2c(-c3ccccc3-c3cnccn3)cccc12 +O=c1cc[nH]c2c(-c3ccnc4cccnc34)cccc12 +O=c1cc[nH]c2c(-c3ccnc4sc5ccccc5c34)cccc12 +O=c1cc[nH]c2c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +O=c1cc[nH]c2c(-c3cnc4ncccc4c3)cccc12 +O=c1cc[nH]c2c(-c3cnc4nccnc4n3)cccc12 +O=c1cc[nH]c2c(-c3cscn3)cccc12 +O=c1cc[nH]c2c(-c3c[nH]c4ccncc34)cccc12 +O=c1cc[nH]c2c(-c3nc4nc5nc[nH]c5cc4[nH]3)cccc12 +O=c1cc[nH]c2c(-n3c4ccccc4c4ccncc43)cccc12 +O=c1cc[nH]c2c(-n3ccc4ccccc43)cccc12 +O=c1cc[nH]c2cc(-c3c(-c4ccccc4)cc4c5c3CCCN5CCC4)ccc12 +O=c1cc[nH]c2cc(-c3c4ncoc4cc4ncoc34)ccc12 +O=c1cc[nH]c2cc(-c3c4ncsc4cc4ncsc34)ccc12 +O=c1cc[nH]c2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +O=c1cc[nH]c2cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +O=c1cc[nH]c2cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3cc4cc5cc[nH]c5cc4o3)ccc12 +O=c1cc[nH]c2cc(-c3cc4ccccc4o3)ccc12 +O=c1cc[nH]c2cc(-c3cc4ccccc4s3)ccc12 +O=c1cc[nH]c2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc12 +O=c1cc[nH]c2cc(-c3ccc(-c4ccccn4)nc3)ccc12 +O=c1cc[nH]c2cc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)ccc12 +O=c1c2c(cc(cc2)c2ccc3CCc4c(cccc4)Nc3c2)[nH]cc1 +O=c1cc[nH]c2cc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)Oc3ccccc3O4)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)sc3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(n3)sc3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4ncsc4c3)ccc12 +O=c1cc[nH]c2cc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)ccc12 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)-[nH]-c4ccccc4CC5)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)c4ccccc4c4[nH]cnc54)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccc6c7ccccc7[nH]c6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5cc[nH]c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5[nH]c6ccc7c8ccccc8[nH]c7c6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4cnc4ccccc45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4[nH]c4cnccc45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c6nc[nH]c6c6ccccc6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cnc5oc6ccccc6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cnc5sc6ccccc6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5cc6ocnc6cc5o4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5cc6scnc6cc5s4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nccc5[nH]c6ccccc6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5cc6occc6cc5o4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5ccccc5o4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5[nH]c6ccccc6c5c5[nH]c6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5sc6ncccc6c5c4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c4-[nH]-c4ccccc4CC5)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c6ccccc6c6nccnc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5cnc6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5oc6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5occc45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5[nH]c6ccncc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5[nH]c6[nH]c7ccccc7c6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4c[nH]c5cc6occc6cc45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4nc5nc6nc[nH]c6nc5[nH]4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4ccc5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4nnc5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cc4nc5ccoc5nc4[nH]3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)-s-c3ccccc3-[nH]-4)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)-[nH]-c3ccccc3-s-4)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)[nH]c3cnccc34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c5ccccc5c5nc[nH]c5c4c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4sc5ncccc5c4c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cccc(N(c4ccccc4)c4ccccc4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cccc4c5[nH]cnc5c5ccccc5c34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3c[nH]c4cc5occc5cc34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3cnc4nc5nc[nH]c5nc43)n2)cc1 +CC1(C)c2cc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)ccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccccc1 +CC1(C)c2cc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)ccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4)c3cc21 +CC1(C)c2cc3c(cc2-[nH]-c2c(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)cccc21)c1ccccc1n3-c1ccccc1 +CC1(C)c2cc3c(cc2-[nH]-c2cccc(-c4ccc5cccc6c5c4-c4nc5cc(C#N)c(C#N)cc5nc4-6)c21)c1ccccc1n3-c1ccccc1 +CC1(C)c2ccccc2-c2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc21 +CC1(C)c2ccccc2-c2cc(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)ccc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc21 +CC1(C)c2ccccc2-n(-c2cc3c4c(cccc4c2)-c2nc4cc(C#N)c(C#N)cc4nc2-3)-c2cc3c4ccccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-n(-c2ccc3cccc4c3c2-c2nc3cc(C#N)c(C#N)cc3nc2-4)-c2ccccc21 +CC1(C)c2ccccc2-[nH]-c2c(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)cccc21 +CC1(C)c2ccccc2-[nH]-c2c(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cccc21 +CC1(C)c2ccccc2-[nH]-c2c1cc1c(c2-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2ccccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2c(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)cccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2c(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2cc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)ccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccc(-c2ccc3c4c(cccc24)-c2nc4cc(C#N)c(C#N)cc4nc2-3)cc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 +CC1(C)c2ccccc2-[nH]-c2cc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)ccc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4c(-c5cc6c7c(cccc7c5)-c5nc7cc(C#N)c(C#N)cc7nc5-6)cccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4c(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)cccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4cc(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)ccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4cccc(-c5c(C#N)c(C#N)cc6nc7c(nc56)-c5cccc6cccc-7c56)c4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4-c4cc5c6c(cccc6c4)-c4nc6cc(C#N)c(C#N)cc6nc4-5)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4-c4ccc5cccc6c5c4-c4nc5cc(C#N)c(C#N)cc5nc4-6)c3cc21 +CC1(C)c2ccccc2-[nH]-c2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc21 +Cc1-c2ccccc2-[nH]-c2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc2-1 +Cc1-c2ccccc2-[nH]-c2cccc(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)c2-1 +Cc1c(C)c(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2c(c1C)c1ccccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cccc1n2C +Cc1cccc2c1[nH]c1c(C)cc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c5c(cccc35)-c3nc5cc(C#N)c(C#N)cc5nc3-4)c12 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc2ccccc12 +CN(C)c1cc2ccccc2cc1-c1ccc2c3c(cccc13)-c1nc3cc(C#N)c(C#N)cc3nc1-2 +CN(C)c1cc2ccccc2cc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c1 +CN(C)c1cc2ccccc2cc1-c1ccccc1-c1nc(-c2ccccc2)nc(-c2ccccc2)n1 +CN(C)c1ccc2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc2c1 +CN1c2ccccc2N(C)c2c(-c3ccc4c5c(cccc35)-c3nc5cc(C#N)c(C#N)cc5nc3-4)cccc21 +CN1c2ccccc2N(C)c2cc(-c3cc4c5c(cccc5c3)-c3nc5cc(C#N)c(C#N)cc5nc3-4)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)ccc21 +CN1c2ccccc2Oc2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc21 +N#Cc1cc2nc3c(nc2c(-c2c(-c4ccccc4)cc4c5c2CCCN5CCC4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cc4nc5cc[nH]c5nc4o2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c(c2)[nH]c2ccc5c6ccccc6[nH]c5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c(c2)[nH]c2ccncc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c5c2CCCN5CCC4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4ccoc4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4ocnc4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4[nH]c5[nH]c6ccccc6c5c4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c(=O)cc[nH]c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2ncc2ccccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2[nH]c2cnccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c5ccccc5c5nc[nH]c5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4cnc5ccccc5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4occc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4[nH]c5ccccc5c(=O)c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4[nH]ccc(=O)c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2nccc4c2[nH]c2ccccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2nccc4[nH]c5ccncc5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2-c4ccccc4CCc4ccccc4-2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2ccc(=O)c4ccccc42)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2ccc4nc5ccoc5nc42)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4c5ccccc5[nH]c4c4c2[nH]c2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4ccccc4o2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4nc5ccoc5nc4[nH]2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc(N)cc2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)CCc2ccccc2-[nH]-4)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)oc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)[nH]c2ccncc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(n2)oc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(n2)sc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4ccoc4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4occc4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c(=O)cc[nH]c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c5ccccc5c5nc[nH]c5c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c5nccnc5c5ccccc5c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4ccsc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4[nH]ccc(=O)c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2coc4ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2c[nH]c(=O)[nH]2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-n2c4ccccc4c4c5ccccc5[nH]c42)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-n2cc[nH]c2=O)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cc(F)c(F)c(F)c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cc4nc5cc[nH]c5nc4o2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4c(c2)CCc2ccccc2-[nH]-4)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4ocnc4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4[nH]ccc(=O)c4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4c2cnc2ccccc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4c2Oc2ccccc2O4)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4ncsc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4sccc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-n2c4ccccc4c4ccc5[nH]c6ccccc6c5c42)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-n2ccc4nc5ccoc5nc42)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2c4ccoc4cc4ccoc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cc4cc5cc[nH]c5cc4o2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)c2ccccc2c2nc[nH]c42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)c2ccccc2c2[nH]cnc42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)[nH]c2cnccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(n2)sc2ncccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4oc5ccccc5c4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4ocnc4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4[nH]c5[nH]c6ccccc6c5c4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc(N(c4ccccc4)c4ccccc4)c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c(=O)cc[nH]c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c2[nH]c2c4ccc4[nH]c5ccccc5c42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c2[nH]c2cnccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4oc5ccccc5c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4scnc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccnc4sc5ncccc5c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccnnc2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cncc4c2[nH]c2ccccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2nc4cc5scnc5cc4s2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2nc4ccccc4s2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2-c4ccccc4-s-c4ccccc4-2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2ccc4cc5ccoc5cc42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2cnc4c5ccccc5c5ccccc5c42)c2cccc-3c12 +O=c1c2ccccc2n(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2ccccc12 +O=c1c2ccccc2[nH]c2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc12 +O=c1ccn(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2ccccc12 +c1ccc(-c2cncc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +c1ccc(-c2cncc(-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccccc4C4(c5ccccc5)c5ccccc5-[nH]-c5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)n2)cc1 +c1ccc(-c2nccnc2-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1 +c1ccc(-c2nccnc2-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cc5cc6occc6cc5o4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cc5[nH]ccc5cn4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccc5c(c4)Oc4cccc6c4B5c4ccccc4O6)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccnc5c4ccc4cccnc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccnc5[nH]c6ccccc6c45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cnc5nccnc5n4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cncc5[nH]c6ccccc6c45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4csc5ccccc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4c[nH]c5nc6occc6nc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4nc5ccccc5c5ccccc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4nc5nc6nc[nH]c6nc5[nH]4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4c5[nH]cnc5nc5nc[nH]c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cc5c(cn4)[nH]c4ccccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cc5cc6occc6cc5o4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5c(c4)sc4ccccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5ncccc5n4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5sc6ccccc6c5c4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccc5c4[nH]c4ncccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccc5sc6ccccc6c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccnc4-c4ccccn4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccnc5[nH]c6ccccc6c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cnc5nccnc5n4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cnoc4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-n4nnc5ccccc54)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ncno3)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ncon3)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cc5nc6cc[nH]c6nc5o4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cc5[nH]ccc5cn4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccc5ncoc5c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccc5[nH]c6cnccc6c5c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cccc(-c5cnccn5)c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cccc5nn[nH]c45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccnc5c4ccc4cccnc45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cncc5c4[nH]c4ccncc45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4c5ccccc5c5cccnc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4ccc5nc6ccoc6nc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4cnc5cc6nc[nH]c6cc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4c5[nH]cnc5cc5nc[nH]c45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cc5nc6ccoc6nc5[nH]4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cccc(-c5cnccn5)c4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cccc5c4[nH]c4ncccc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccccc4-c4cnccn4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccnc5[nH]c6ccccc6c45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccon4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cncs4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4coc5cc6ccoc6cc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4coc5nc6[nH]ccc6nc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-n4cnc5nc6nc[nH]c6nc54)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4c5[nH]cnc5cc5nc[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4c5[nH]cnc5nc5nc[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cc5ccccc5s4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc(-c5cnccn5)cc4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5ccc6cccnc6c5n4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5nn[nH]c5c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5[nH]nnc5c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc(-c5cnccn5)c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5c4Oc4cccc6c4B5c4ccccc4O6)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5c4[nH]c4ncccc45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5nn[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5[nH]c6ncccc6c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5[nH]nnc45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cnc5c(ccc6cccnc65)c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cnc5ccccc5n4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5ccsc5c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5[nH]nnc5c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc(-c5cnccn5)c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5c4cnc4ccccc45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5c4sc4ccccc45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5[nH]c6cnccc6c45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccno4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cnc5c(ccc6cccnc65)c4)c32)cc1 +c1ccc(C2(c3ccccc3-c3cc4cnccc4[nH]3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4cccnc4n3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4nn[nH]c4c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3cccc4sc5ccccc5c34)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccnc(-c4ccccn4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nc4cc5ncoc5nc4o3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nc4ccccc4c4ccccc34)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nccs3)c3ccccc3-[nH]-c3ccccc32)cc1 +CC(=O)c1cccc(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)c1 +CC(=O)c1ccccc1-c1cccc2c1-[nH]-c1ccccc1C2(c1ccccc1)c1ccccc1 +Cc1-c2ccccc2-c2cc(-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)ccc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cc2-1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +N#Cc1cc(C#N)c(-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c(C#N)c1 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1ccc(-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1 +N#Cc1ccc(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)c(C#N)c1C#N +N#Cc1cccc(-c2ccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cc2)c1 +N#Cc1cccc(C#N)c1-c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1 +N#Cc1ccccc1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-[nH]-2 +N#Cc1cnc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)nc1 +O=C(c1ccc(-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1 +O=C(c1cccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3c2-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)c1)C(F)(F)F +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-[nH]-5)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4-[nH]-c4ccccc4C5(c4ccccc4)c4ccccc4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +O=C(c1ccccc1-c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1)C(F)(F)F +O=C(c1ccccc1-c1cccc2c1-[nH]-c1ccccc1C2(c1ccccc1)c1ccccc1)C(F)(F)F +O=C(c1ccccc1-n1-c2ccccc2C(c2ccccc2)(c2ccccc2)c2ccccc2-1)C(F)(F)F +O=c1c(-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c[nH]c2ccccc12 +O=C1c2ccccc2C(=O)n1-c1cccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c1 +O=C1c2ccccc2C(=O)n1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-[nH]-2 +O=C1c=c(-c2ccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cc2)C(=O)[nH]1 +O=C1c=c(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)C(=O)[nH]1 +O=c1cc(-c2cccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)c2)[nH]c2ccccc12 +O=c1cc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)[nH]c2ccccc12 +O=c1ccn(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c2ccccc12 +O=c1ccn(-c2cccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)c2)c2ccccc12 +O=c1ccn(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c2ccccc12 +O=c1cc[nH]c2c(-c3cccc4c3C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)cccc12 +O=c1cc[nH]c2c(-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cccc12 +O=C1[nH]C(=O)c2cc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)ccc21 +O=s1(=O)-c2ccccc2-c2c(-c3cccc4c3-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cccc2-1 +O=s1(=O)-c2ccccc2-c2cc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)ccc2-1 +O=s1(=O)-c2ccccc2-c2ccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cc2-1 +O=s1(=O)-c2ccccc2-c2cccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)c2-1 +O=s1(=O)-c2ccccc2-c2cccc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)c2-1 diff --git a/examples/tadf/TADF_angle/angle.dat b/examples/tadf/TADF_angle/angle.dat new file mode 100644 index 000000000..6e14b36a3 --- /dev/null +++ b/examples/tadf/TADF_angle/angle.dat @@ -0,0 +1,5136 @@ +0.007244423 +65.01516273 +53.67854506 +50.40384344 +62.38276526 +89.98273358 +89.94897629 +27.50861251 +89.90636837 +15.2624566 +58.93331125 +89.9933551 +59.75817598 +47.11678539 +35.23804287 +71.87082031 +49.82473469 +42.32577 +89.86599528 +39.99855243 +55.92156236 +22.6326025 +35.89981468 +38.02934486 +68.28320598 +35.09701538 +54.85061353 +53.60518788 +37.64433131 +0.823960687 +49.02319879 +22.96459392 +0.008755643 +0.008491876 +32.53156316 +0 +15.36723494 +0.00506891 +0 +0 +0 +0 +33.72421656 +35.11256843 +41.87594605 +32.4586105 +34.87389322 +34.86753044 +0 +0 +16.49370432 +0 +62.51497187 +0 +0 +0.009508249 +54.82628843 +40.69775618 +0 +42.1730085 +39.12316748 +43.92522424 +40.02788415 +36.9000711 +65.82308462 +52.41137685 +45.87958576 +42.08548545 +34.97663312 +31.36088116 +53.74670216 +42.44424831 +45.32089539 +29.96091368 +41.55532446 +45.8822155 +36.95631987 +36.46324976 +49.17755444 +43.27470788 +46.49091756 +32.01903105 +36.6616505 +67.87790601 +34.55394903 +51.13462519 +27.93633117 +61.21678311 +33.14638821 +0 +81.02740599 +74.44688549 +78.22171953 +64.26130928 +61.24555989 +53.15846756 +46.94255504 +45.30065337 +36.71648222 +46.57263955 +30.77627 +0 +43.23674527 +34.72878436 +29.87464878 +47.3060847 +45.20996436 +35.74470709 +0.030869982 +69.70625897 +53.70704402 +66.4198474 +54.27483086 +43.65999651 +44.50015485 +49.14345145 +66.12987824 +53.6923052 +33.80544129 +33.2386179 +35.41245499 +47.27999361 +66.33542468 +41.44294811 +38.73658343 +53.99164975 +54.72511583 +43.86392791 +33.88964561 +42.04254084 +55.1321893 +33.36000154 +48.5046266 +46.77647525 +45.08507276 +37.22847018 +36.00976305 +0 +67.10340989 +38.20030008 +41.82568571 +67.73699002 +43.79857093 +40.26667583 +35.67708917 +67.44429404 +53.99793801 +34.61238236 +47.42309931 +56.06367485 +58.50358677 +37.92709303 +57.59558134 +51.758282 +44.09904612 +42.05077269 +58.7989168 +44.6682045 +52.9445643 +52.0360258 +44.0465298 +84.93058678 +80.38913722 +73.4224324 +66.52503279 +70.47062312 +67.90850597 +58.84684288 +52.86005021 +44.35858613 +53.80103358 +71.03719546 +69.28706118 +69.27376344 +62.74930615 +58.51029167 +61.44744673 +40.70789341 +32.06742101 +83.44277553 +72.62117546 +57.23216895 +68.75194384 +57.38623142 +78.75500134 +56.63855677 +71.29857151 +58.01850679 +82.13387891 +42.90660473 +46.69749724 +48.84846128 +58.61441725 +46.6404079 +61.01089508 +58.34146064 +83.93583436 +78.59747069 +78.85100654 +60.29075462 +54.61446368 +46.92996526 +26.82564606 +52.3482422 +0 +0.008825024 +45.43438486 +29.07173407 +0 +0 +0.005054886 +0.022989 +44.63564893 +0.004448871 +53.67235424 +15.51155834 +36.70366839 +31.0014262 +51.41959696 +42.1225969 +64.59363135 +34.02355143 +38.31161347 +71.58079935 +58.36196792 +57.57674614 +46.19356495 +49.50711408 +45.58057577 +57.63305984 +0.010516524 +0.016726091 +0.005078098 +66.90641481 +52.95350797 +48.09330666 +64.05710305 +44.43345006 +0.008544267 +34.93588706 +19.96948475 +42.3090752 +44.13545809 +56.8698892 +47.44467944 +89.51880131 +0.022887628 +51.13662974 +29.79098638 +0.031469243 +62.63321239 +31.91516073 +0.004246987 +66.14126262 +0 +41.28445706 +44.07755039 +50.48946556 +43.19513018 +27.0670677 +0.008552867 +24.64690423 +49.08167983 +30.0767043 +0.015821227 +43.13259228 +55.1410402 +60.26332482 +58.62302506 +39.67899332 +43.209876 +43.19990511 +0 +0 +0.045854787 +0 +0 +0 +0 +0 +0 +0 +0 +0.008182737 +49.66078278 +0.187927169 +0 +0 +31.77285929 +0 +0.029495096 +52.59892683 +0 +20.86673541 +23.12573454 +35.33351052 +0 +19.94209766 +0 +38.3910164 +31.20192433 +33.24751649 +64.05696785 +57.59365823 +44.38800464 +49.61894338 +0 +0.027000809 +0 +0.015769855 +0.004526423 +0.00449657 +0 +0 +0.004547084 +51.80088625 +75.26853476 +73.4928056 +80.99380679 +88.83494638 +59.44441301 +62.08030883 +62.82113481 +66.5424064 +59.26587392 +61.30117346 +57.72843192 +89.78976024 +81.09361859 +58.06202675 +60.51053742 +63.69910399 +52.02886789 +39.97444525 +41.5172948 +44.72313602 +59.51994778 +48.06423805 +19.1386398 +37.79757951 +89.36200394 +48.88191435 +49.3920839 +62.13134936 +38.276309 +48.06875648 +41.68760949 +0.016549332 +89.99711755 +87.28142354 +86.63857408 +60.22561673 +52.17530176 +74.93623024 +48.82588424 +44.84914132 +77.31047255 +66.81647136 +61.2457057 +63.48722403 +61.38178477 +89.96783025 +89.99833485 +35.96509446 +37.82711747 +38.23927159 +38.50278838 +37.63901416 +37.54720742 +15.3646989 +48.17615351 +49.26597671 +47.78451074 +38.20946485 +38.82266559 +45.8022111 +39.09860561 +0 +38.99559274 +39.57368868 +42.15604629 +89.9932759 +37.70055637 +38.19817107 +0 +25.12254849 +0 +0.007805075 +52.69885446 +58.06595921 +0 +0 +0 +21.47011833 +0.018203625 +0 +0.019331254 +50.33825111 +47.36304775 +46.33416779 +39.96040087 +31.60178983 +44.9064047 +34.37917391 +37.80491556 +37.86836139 +0.003419015 +21.88158469 +0 +5.309440349 +18.88951483 +19.59902418 +0.009803763 +0 +0.045029071 +44.6321368 +44.54232838 +44.54413875 +46.44877297 +89.67257748 +43.08610523 +18.22558855 +16.50257433 +6.204385912 +5.520487113 +0 +0 +0 +0 +0 +0 +63.93940577 +40.03641874 +43.4702169 +40.65837165 +43.69353852 +0 +32.59066399 +45.85915243 +48.72126899 +89.47152809 +32.57281079 +46.47189923 +46.44727469 +0 +0 +41.24723912 +34.67238726 +37.01840222 +14.48225658 +0 +0 +0 +0.018504598 +35.225676 +0 +0.008625714 +0.014915178 +49.61231893 +0 +0 +0.004691101 +0.015550698 +49.17120241 +39.13319313 +42.93808184 +32.12905256 +0.004607215 +38.11690842 +0 +42.72016468 +46.56202961 +5.72469816 +0 +39.8880874 +0 +31.3879825 +32.14311916 +62.21232101 +54.68253706 +36.02989668 +0.009335863 +56.06963832 +35.32320419 +35.26805907 +35.47915122 +48.30954572 +44.65688961 +73.03042462 +63.76888151 +52.90770063 +32.01949217 +3.318206054 +42.98444324 +75.5990075 +61.54069123 +75.05483946 +79.34211016 +69.26834107 +78.19835489 +83.85321861 +61.18410955 +23.97404357 +29.01109054 +89.99775915 +46.88863746 +32.77449435 +36.21058545 +35.7373464 +34.67133241 +36.87692553 +36.74816988 +53.87629314 +44.54586494 +67.64073565 +62.3512836 +44.04082047 +33.63542672 +38.67269086 +36.41524193 +45.06064991 +57.36735206 +52.53585984 +64.17606884 +52.517679 +31.06213502 +32.62926619 +0.020951764 +43.31090964 +21.70686302 +0.004734433 +0.009350598 +0.021260461 +0 +25.99804825 +51.24723465 +39.74839068 +37.99492052 +0 +38.51130921 +46.56347041 +0 +0 +0.004778258 +21.1491371 +0 +32.84559359 +57.36943793 +57.59689113 +57.62548772 +75.98543846 +87.72577151 +57.14377351 +50.59430582 +81.2628114 +71.85714741 +67.70733492 +50.09755489 +45.14960603 +18.37065932 +19.66103009 +15.80375432 +0 +0.004888145 +0.009476115 +0 +0 +43.26010089 +42.14197065 +49.66422964 +52.29059035 +0 +36.1532851 +0.650029611 +16.75157362 +0.004639848 +27.58990248 +51.124926 +0 +0 +0 +2.730342429 +0 +0 +0.009289508 +0 +0 +0 +0.009152875 +0.004719495 +22.20383864 +26.85510239 +33.2723959 +57.61536699 +55.52926934 +0 +31.6603378 +28.29629078 +53.7885625 +54.5007088 +53.0089689 +54.15937593 +46.83895169 +55.60026012 +49.14843819 +49.06753833 +49.12581002 +44.81924467 +58.13337579 +86.65358679 +66.58103689 +36.27062756 +36.10715459 +64.60007214 +53.75349829 +55.61613222 +49.59694475 +50.45601824 +56.63318073 +55.96367681 +51.58353078 +78.96500269 +85.36834684 +70.73556241 +51.76515401 +52.21540473 +63.93308044 +78.94457841 +77.75933448 +25.88121101 +37.66231932 +37.793508 +40.06814971 +39.36406177 +39.69506046 +40.24886849 +64.2248372 +23.86245176 +62.72603344 +62.26603918 +54.07279275 +50.40797321 +66.5511334 +65.42620292 +28.09190069 +22.46311654 +85.62503293 +54.91716969 +55.08966717 +49.12999161 +32.1663434 +77.06135101 +81.54227734 +68.80697214 +3.210143412 +17.67271574 +33.92031236 +36.26067312 +36.21052276 +35.67283233 +47.46388945 +52.60510352 +31.75701111 +43.38445262 +41.41650643 +35.45325713 +37.09771912 +46.16923778 +37.04148859 +44.04924829 +65.24502898 +35.55142203 +54.69101793 +34.77514555 +37.75923326 +54.44398579 +20.20678771 +35.5626175 +46.48250544 +37.96387213 +40.99991096 +54.0723885 +50.55314554 +50.31586401 +49.22124254 +63.35939671 +79.53880631 +41.85488305 +51.4479562 +25.08065309 +36.23343791 +41.93656918 +26.47524571 +44.88767857 +57.41395599 +89.84990772 +46.07339703 +89.97975859 +51.74307282 +0.018226366 +0.008409422 +0 +0 +33.94493515 +44.73813372 +45.13789739 +45.71389868 +37.25565711 +37.96002264 +36.09667066 +50.52162404 +42.2404851 +50.50262183 +65.72503549 +25.73181851 +66.64225992 +51.08118694 +41.52656172 +18.32401879 +0.022783153 +33.56183353 +40.93065713 +0.021229831 +12.38156502 +0 +22.81779186 +57.19641854 +63.51227653 +72.61836859 +43.85789137 +50.33311297 +45.71506443 +44.41963547 +24.6663641 +55.83681169 +55.88145031 +57.1719452 +58.48327396 +67.9049154 +18.20769204 +16.56155157 +33.22790818 +38.17896295 +36.35667739 +43.82534962 +1.667979395 +0.476784668 +1.482682845 +61.1637804 +21.64302533 +17.38538084 +36.96603091 +37.40428776 +44.52429295 +68.79337764 +0.312568091 +35.7234584 +52.04438414 +42.43722088 +55.05979104 +59.26173668 +60.54903585 +67.66896418 +55.91221453 +42.65138422 +55.19729646 +62.09709648 +61.93232271 +74.09442384 +20.07950119 +83.15122528 +57.72477901 +89.9965316 +48.47052815 +27.87415874 +15.2371261 +89.99757586 +89.99258931 +22.95431896 +89.99946415 +14.31005846 +79.57530238 +89.99918898 +90 +89.99634655 +89.99795116 +44.35808855 +43.95966568 +16.84004092 +47.6088826 +0 +0.004363193 +0 +0 +37.59660342 +38.08277006 +37.49740015 +38.14914418 +0 +0 +0.004560675 +0 +0 +32.19528955 +0 +49.528947 +52.98186391 +52.79036931 +58.52727927 +37.56841867 +47.5657526 +38.9527538 +43.36332685 +0 +33.7756349 +35.51947253 +35.78916645 +35.71198607 +47.05814205 +0 +20.79423857 +21.27185265 +35.46196924 +0 +0 +0 +0.003515818 +57.36447934 +36.55378398 +41.42981299 +64.32049105 +87.16780154 +67.40279247 +68.75450194 +67.27040195 +75.02298587 +44.36078387 +62.10000886 +57.34214142 +57.53144594 +0.015377208 +49.34143568 +75.32448378 +57.11635689 +71.42301787 +49.86815051 +60.65437287 +89.75000281 +85.50397561 +81.08504174 +62.54193811 +84.50712418 +41.43020557 +37.7863668 +54.53865987 +0 +0 +0 +0 +0 +0 +0 +0.007601463 +0 +0 +0 +0 +0 +0 +23.18368763 +36.80516908 +30.65640084 +24.14199787 +57.73227083 +54.37252451 +18.35802113 +70.32878974 +52.29517522 +86.73728655 +48.29144022 +43.17213466 +52.40332291 +38.62588452 +63.43694886 +84.86697158 +29.13830228 +89.73921091 +89.93335726 +59.39502871 +65.52799941 +27.79806709 +89.91271877 +89.40294257 +55.72968121 +62.23384481 +63.70463369 +69.14599787 +70.1256119 +67.8573165 +57.8820902 +47.32840269 +51.40306204 +88.93675669 +58.19372779 +62.89730098 +61.73123145 +62.42244829 +64.63717614 +73.64640814 +63.35040646 +57.36421578 +47.70524956 +46.59432967 +43.75386629 +60.50572529 +60.02228483 +67.21509028 +56.60392347 +44.57419344 +39.06322846 +71.83975023 +88.94494757 +71.7099189 +63.95175135 +29.31830892 +32.78506453 +32.71690125 +14.17239378 +36.19798477 +36.42163819 +62.98144447 +38.77902414 +48.81781672 +37.20614162 +36.05663711 +0.808215017 +30.37366017 +0.087154246 +42.75166313 +21.4392348 +36.27446382 +48.1584976 +71.99645553 +54.64382283 +54.40737006 +2.050885516 +23.86479183 +3.720066891 +4.369006912 +1.154742698 +0.46530444 +49.74057218 +27.77860141 +63.58565979 +55.32357802 +56.76236021 +57.00202387 +75.50565717 +72.96449006 +59.98416281 +88.85756215 +63.82807338 +67.56979456 +28.4327751 +36.13805256 +41.78184538 +35.01282155 +9.753985766 +5.080869932 +9.715301458 +12.83504371 +24.9125384 +86.67384076 +83.63306473 +7.653993937 +3.085682684 +24.36064182 +28.99852545 +82.17902462 +48.47070236 +60.61354441 +54.54552492 +52.15764302 +67.28741548 +40.72267819 +81.28123891 +9.354670481 +28.70543702 +53.974295 +46.21282963 +39.60607561 +0.004755614 +45.85456523 +47.55566394 +45.91970821 +44.8728043 +47.93578071 +47.51134974 +47.63846728 +72.1583738 +0 +47.46076962 +47.09006559 +18.3900782 +33.18345361 +0 +47.15987786 +45.05737064 +55.31144687 +35.52564265 +35.67787283 +36.03322245 +34.33856289 +0 +69.57477059 +35.4945789 +35.71316544 +36.26193243 +36.18263067 +36.23555929 +35.52805655 +35.49398163 +36.08630531 +48.77134564 +44.82297109 +63.24144259 +0.004763086 +37.17478131 +0.005088803 +56.32072396 +71.41835845 +30.94506396 +0 +35.21347955 +36.26502617 +39.54684877 +38.14920832 +38.67761436 +37.72030627 +37.26428081 +37.73150962 +53.70391285 +44.84474019 +45.77274768 +66.42411892 +54.77189808 +54.39086321 +62.91411203 +35.39086359 +0 +0.004760185 +47.46988953 +47.03128614 +55.76261341 +57.46741089 +66.09897381 +57.34676265 +65.12570115 +70.31989886 +68.6531292 +68.57926229 +83.76268043 +82.04868856 +70.38608972 +73.06574937 +68.11492322 +53.13626652 +63.46444708 +65.55894029 +65.45915178 +51.29308906 +56.25555774 +87.98889012 +57.11118493 +89.11634984 +56.98546271 +89.95435046 +36.37425865 +34.39326869 +46.63817778 +45.60203127 +45.05921824 +47.21652756 +46.65548207 +37.22560458 +61.32359428 +48.71740747 +52.8499695 +57.73460827 +55.00658274 +45.05974899 +35.71182722 +32.85535479 +59.15510164 +60.62849169 +89.99322011 +0.008450445 +54.63742105 +45.43217784 +55.28799792 +55.96518962 +56.87812151 +65.28166843 +58.93991666 +52.14322062 +84.86185159 +83.27160117 +40.51519762 +44.0814553 +43.21073964 +48.10793576 +0 +0.013297033 +62.36638026 +70.57909623 +61.52798228 +89.65753211 +42.86868867 +30.45880738 +46.50413663 +0.00953964 +36.14468505 +36.99722577 +36.19414222 +55.87491385 +36.94517505 +36.09614499 +36.01825904 +36.3225344 +76.88754086 +42.07876439 +61.99432635 +51.8694029 +0.00464219 +38.47757481 +44.15781476 +46.04142231 +36.75051864 +37.59603771 +38.08328437 +38.03152845 +37.68203464 +37.62510025 +36.45516685 +48.22414805 +44.52654984 +45.7449386 +62.76934051 +52.49532081 +50.86143934 +0.004610924 +44.82657428 +54.18950866 +0.004370991 +20.44830801 +34.60124663 +33.77961983 +0.005095617 +0.007791594 +44.67415944 +48.5802504 +44.84991006 +0.102358256 +39.98678831 +41.50715834 +40.34748228 +40.79453231 +42.30607536 +40.26824531 +39.64006118 +42.17263976 +40.23405173 +38.77521099 +45.50863177 +32.84495724 +87.36481666 +76.05060904 +54.31909102 +43.8982681 +53.33204596 +33.19979028 +45.9353115 +0.098321961 +0.026182707 +50.53891454 +89.69248937 +76.34021016 +89.40463307 +87.04557314 +44.85331071 +89.99676737 +89.3856903 +0.004987378 +37.23828829 +47.30375605 +52.19237691 +0.008202767 +53.85424391 +0 +35.48704523 +0 +54.28010757 +35.10511262 +37.44773101 +37.48028823 +36.80432673 +36.96232011 +35.94992697 +47.39880039 +51.01442923 +52.33632676 +50.38777346 +0.000375833 +0.003425122 +16.28276389 +44.30614554 +13.62317216 +0.019626816 +0.01180416 +39.74988349 +48.81428548 +21.91557598 +45.98538893 +44.72597562 +35.12697326 +0.021110557 +0 +0 +0 +45.69936936 +46.35250546 +46.76145239 +36.68202555 +36.8731003 +47.19941261 +38.87429597 +46.61076322 +44.59225339 +65.96274926 +45.22710788 +49.48863593 +71.97612229 +40.99282158 +72.75630239 +0 +9.34E-05 +34.70543878 +35.26037305 +0 +46.47228922 +37.96816894 +49.89793212 +18.24695615 +0 +53.02398751 +31.06999048 +0.011841927 +61.53660586 +58.43502142 +0.027678509 +41.47096719 +42.07836332 +0.040256098 +45.16957127 +46.86388434 +52.86846042 +46.71441199 +43.96877307 +57.36460743 +57.44312499 +66.745303 +44.12140375 +52.78332877 +0.016643507 +0 +0 +21.60044498 +67.28787332 +62.83589065 +45.07942597 +37.92272371 +48.73959729 +48.93114111 +48.96469424 +48.55090479 +49.65941794 +49.10066298 +61.87993938 +55.18007878 +56.26878337 +62.07332901 +57.44674661 +59.86336591 +42.62230324 +49.88462502 +61.57511735 +37.17704916 +0 +0 +38.02951737 +71.96317994 +66.71141415 +42.07396974 +56.94430008 +39.05803007 +0 +0.004616171 +0.018139639 +53.71576994 +33.98036851 +45.8802806 +35.51971913 +43.25660578 +44.22398486 +74.53064573 +0 +52.10875203 +34.14592458 +35.55863928 +0.004631402 +43.28987996 +55.09492932 +33.57247673 +50.22076954 +48.30533565 +63.9130795 +46.64660958 +73.29137258 +54.14088638 +69.70898933 +0.013720133 +69.34389213 +75.77107069 +80.64551149 +0 +0 +0.004639428 +0 +0 +0.004333158 +35.77473978 +0.007064521 +31.97186192 +48.11633306 +0.008961492 +38.1086927 +39.73520836 +0 +0 +0 +0 +41.89945277 +89.9986548 +50.2076977 +49.17862542 +50.00690264 +54.2308392 +0.064504512 +46.94235311 +57.87807092 +60.70129532 +47.17243538 +50.37238898 +50.39116105 +48.96331999 +51.17973899 +51.18509341 +56.24379538 +0.005054868 +37.72234953 +0.035293585 +0.010695362 +41.02861176 +80.83777234 +36.74865731 +37.5282402 +38.31676666 +38.2828516 +37.30739765 +37.30907684 +68.15177447 +60.75766034 +22.55480309 +42.54166628 +0 +0.009321738 +0 +38.13272869 +38.47145428 +63.80377082 +61.67220644 +76.75645947 +71.93604098 +76.41123816 +55.47345067 +39.17322941 +89.66273721 +38.34857558 +0.004644348 +0.018512513 +0 +0 +0 +0 +0.004747385 +0 +30.7226979 +48.361023 +0 +36.32034305 +38.860042 +0 +0.007808574 +49.47811079 +39.13380356 +89.94868336 +62.99837326 +64.11842789 +64.57862198 +65.53101145 +65.04383597 +48.09999308 +49.72909108 +22.6169107 +86.40438332 +69.01522611 +65.3331496 +45.19825674 +0 +33.90954584 +34.58996344 +0 +33.28608858 +33.80722731 +44.12139197 +41.75101271 +64.04373733 +47.04864899 +43.04305081 +55.43395501 +29.96144173 +0.008745483 +25.84253321 +31.42196982 +0.004540345 +46.56082716 +38.72452845 +29.16692316 +0 +0 +0.004683418 +0 +0.019326185 +35.89673056 +89.937201 +55.96776635 +66.01513103 +72.98125252 +50.92693182 +67.1622254 +72.34944341 +89.96344033 +13.79078015 +23.3747828 +22.19470413 +56.17363202 +19.2968804 +89.97973088 +45.44631807 +45.4239169 +45.99346559 +44.64137875 +46.53478685 +54.218119 +51.95330729 +43.98305566 +46.26751553 +61.27830426 +81.26699135 +65.91477264 +36.57925374 +63.7079493 +89.62594642 +28.31767519 +0.020405098 +0.011415395 +89.87017301 +89.79258925 +28.25494016 +45.5661029 +46.63021912 +51.68615817 +58.7505973 +51.01149802 +42.31922338 +0 +54.36015851 +0 +32.15444334 +54.31279263 +51.46849416 +51.36037818 +44.04640002 +0.004672907 +64.73168222 +50.66018096 +44.32075905 +0 +38.6523568 +45.59056237 +65.92479718 +52.40888177 +45.93024623 +0.031841852 +26.92376404 +0.017322314 +0.005112573 +0.015523445 +66.10557249 +45.77837132 +49.83587472 +65.28041952 +64.04991597 +68.3752202 +68.21688664 +63.54863048 +84.10177936 +0 +20.83957084 +0.021556898 +0 +41.27544715 +46.88581582 +55.43078993 +54.90794169 +38.76986867 +34.25175129 +51.90974326 +0.004360326 +37.38329191 +49.74521192 +46.04232343 +45.95865684 +26.59280945 +0 +41.31965369 +0.01551338 +56.14096885 +49.13148492 +45.75384644 +38.2083672 +63.7611965 +50.14314686 +35.98519904 +48.48630149 +44.10147165 +45.35943543 +44.35237483 +53.52287398 +30.55830954 +0.00457774 +58.51058561 +59.81981467 +58.89688882 +62.96507691 +69.12986709 +88.34257257 +70.68131984 +83.89302553 +89.08828 +64.506427 +43.86012365 +42.09377828 +56.94304587 +56.16674756 +0.071938383 +0.012061877 +51.72839882 +89.98569297 +17.76068873 +0.017387291 +0.00955823 +0 +0 +0.009523662 +0 +0.009560133 +0 +0 +0.009429237 +0.009226157 +49.30739075 +49.85938681 +0.004600741 +0 +0.011630926 +44.8362979 +45.60913837 +54.44609479 +34.83582507 +43.26702544 +52.16976499 +52.98233126 +53.25978031 +52.94108585 +54.42283297 +53.67593495 +53.31453886 +58.21568955 +57.09821689 +63.35567207 +58.99493412 +39.92334239 +26.44342095 +35.0338666 +71.75082464 +68.75354786 +0.009527415 +0.012892945 +0.008045065 +0.012445011 +34.78282384 +32.0103402 +0 +40.52181391 +50.2354808 +0.004776599 +0.004782713 +0 +0 +0.024289353 +59.37607219 +32.81059223 +48.06816643 +55.74624964 +38.36885536 +38.1759262 +36.05085447 +38.57111897 +38.74651423 +38.99748124 +40.2383408 +54.0075683 +27.61156409 +17.17989949 +43.91541959 +28.05346407 +32.01741614 +67.60649476 +51.16230834 +52.0481958 +50.19691324 +50.55838116 +53.7760862 +54.37578908 +68.80387927 +54.75613579 +67.96364202 +68.60561349 +52.29197569 +56.03833797 +57.56414156 +89.75394916 +33.40928804 +45.33111599 +45.56341092 +54.83877843 +30.53431028 +0 +0.00465786 +0 +36.26583752 +37.70089865 +37.89345186 +38.98374999 +0 +0 +0 +0 +0 +0.021808836 +0.004504703 +57.78878221 +50.28281422 +54.34968665 +53.10702848 +47.19010952 +41.06864346 +88.63330527 +83.79341702 +0.009973246 +0 +18.1547024 +0.004597883 +0.01288324 +0.02605678 +38.31898225 +33.09158463 +0.0046286 +0.009469951 +45.46659411 +21.68928825 +20.75766949 +37.83175549 +16.16488438 +0.040003867 +0.005055857 +0 +0 +0 +0 +0.399418609 +0 +0 +0 +0 +0 +0 +0 +0 +0 +0 +0 +0 +47.59574518 +17.94043112 +0 +0 +0.015356044 +35.70500832 +21.16291821 +0 +0 +0 +0 +0 +0 +0.011931837 +36.93653334 +0.008755057 +0 +0 +0.008479022 +0.003444093 +0 +0.004659054 +34.83763284 +74.46709365 +47.06833619 +57.90680426 +0 +0 +29.38435881 +0 +0 +0.0047057 +0 +9.190740774 +47.2544342 +0 +45.49523528 +1.525388666 +24.99931688 +20.34039169 +21.12155756 +0 +35.8954639 +33.13064644 +41.70718441 +0 +0.028556844 +0.004618258 +35.5594278 +35.98603045 +40.6706985 +43.92933703 +44.44422224 +38.05881954 +41.51631832 +43.23782221 +43.08728004 +42.07908916 +42.2728174 +42.38383244 +47.46428263 +40.87667482 +71.32917053 +41.01159919 +41.88804977 +47.01637782 +89.95222458 +56.34182953 +61.85053212 +45.99799958 +54.63525068 +56.77413029 +56.98384883 +56.88163568 +55.74639773 +70.67610249 +73.75896344 +53.28191243 +66.79437394 +58.65237714 +59.77644513 +0.003461444 +82.0932996 +62.78183842 +31.77166143 +55.03206703 +51.91094759 +53.23742886 +89.29317645 +55.47435402 +67.09544616 +87.08196345 +75.57863094 +68.945445 +61.45186337 +54.27201741 +59.60120786 +0 +72.05529384 +50.63189441 +44.13588215 +44.73735786 +35.84077499 +52.1085022 +35.01150903 +37.43424257 +37.91114132 +36.73450331 +55.8023642 +54.98163524 +63.01927097 +38.2472791 +36.77655991 +45.5026323 +0 +0.007805294 +0.004694967 +0.004326985 +0.004609908 +0.004413713 +26.66881499 +39.11475479 +45.59668818 +0.004345875 +0 +0 +2.655304578 +10.88209025 +40.21629691 +31.72324415 +32.03607704 +41.73257711 +0 +0.194965698 +35.84413246 +35.28361512 +37.34596106 +37.46379001 +64.71668347 +35.57397236 +53.40236822 +16.02608616 +5.377021573 +0 +42.34119181 +34.58078608 +25.38395845 +36.78729464 +44.67779094 +0.009470809 +0.012889688 +0 +0.004673384 +0 +39.73547601 +0.039334246 +49.03292531 +0 +35.51670299 +0 +21.59859801 +0 +38.62953188 +31.84741556 +0 +0 +0 +0 +15.19612356 +0 +0 +0.009291257 +0 +0.00820042 +52.33169153 +53.52896844 +43.05891401 +39.25639744 +0 +45.21703894 +0 +24.78781643 +35.06749931 +41.51637675 +0 +0 +37.77461776 +0.00917032 +37.41110833 +37.13583145 +55.91841319 +43.45199598 +44.36853128 +62.23141016 +37.49281735 +0 +44.5875449 +18.17188904 +0 +42.9471271 +71.93896924 +43.70659886 +51.00293438 +52.01259861 +52.1054389 +52.49654869 +52.45814951 +70.45087452 +0.027930134 +65.01863509 +53.00398948 +77.40575077 +89.40395004 +38.21995002 +0 +38.44123722 +0.007803135 +45.83896578 +0 +37.05827224 +44.88292318 +34.53730427 +48.03997283 +46.84052973 +0.00510141 +0 +0 +38.66161648 +39.15526222 +37.95630609 +0 +89.97010154 +0.013702214 +0.004695967 +0 +0.003508735 +0 +70.56310145 +30.96925208 +0.004317213 +37.83656217 +7.716104661 +0 +56.4481644 +31.04022735 +0 +36.3936816 +0 +41.9869015 +49.19327386 +19.97433215 +0 +0 +0 +0.004098148 +0 +0 +0.008933109 +0 +10.92437432 +58.22486242 +61.05640889 +39.12312889 +49.05693607 +62.91448647 +64.1266697 +52.09212621 +49.87970513 +31.98150503 +69.26406513 +53.90372534 +32.5685167 +44.04949744 +44.13359212 +46.63548276 +45.47109663 +32.51392417 +0 +0.00466633 +34.2803934 +31.5431101 +0 +38.28597259 +38.69207529 +37.63846066 +0.018891549 +36.8010179 +35.24435062 +37.56554147 +38.97797618 +66.45714437 +59.72826738 +33.05439621 +68.09065305 +44.43368479 +20.01139161 +23.50708438 +0.021629191 +0.004176169 +85.26988062 +43.64890172 +0.012280822 +0 +0.01269775 +0.004735334 +0.004787318 +56.02112824 +47.08608846 +0.012849278 +0 +0 +0 +0.009699911 +0 +0.013092142 +0.009376752 +0.013979084 +0.003515368 +0 +0 +0.003541563 +0.011964498 +4.497683051 +89.99736039 +60.02743837 +20.61382716 +22.58023572 +22.06996706 +51.68064323 +0 +54.9187825 +38.77139551 +39.15374478 +39.31054991 +24.15190884 +0.004567225 +0 +0.008433371 +0 +0 +0 +64.38904302 +55.53264315 +50.13024308 +46.48430344 +0 +0 +19.98895046 +52.20924556 +24.24237032 +7.590793132 +0 +0.0083278 +0 +0 +0 +0 +0 +0 +0 +0 +86.00998264 +89.09175628 +39.6217586 +38.58965819 +39.38158521 +40.37815235 +0.049985748 +89.73580497 +45.43196659 +46.11124721 +0.005063255 +0.178658284 +0 +0.012654999 +0 +0.086945701 +0 +0.004614476 +0.019965825 +0 +38.31107498 +90 +35.40969045 +35.68778309 +31.1248132 +43.26149916 +0.050911457 +21.28689139 +35.06117722 +35.46585854 +34.21406893 +35.0424959 +32.44599836 +35.21931554 +36.05063219 +0.166713197 +35.04613002 +36.9270667 +36.0951019 +36.26733486 +53.1984346 +60.32915047 +81.2889299 +54.5807393 +47.21449815 +43.44651102 +56.31200005 +51.52418381 +50.69483596 +41.67386867 +40.00777063 +54.25398552 +52.77592655 +0.150582641 +9.949007234 +0.098532092 +0 +32.97421477 +89.99536862 +63.92195693 +51.78306534 +89.0210299 +36.09783376 +89.18521524 +76.41719306 +84.30675314 +86.28095058 +50.63203014 +0.055058317 +35.62888439 +35.98160248 +34.51609124 +36.21600169 +0.188141147 +37.2069855 +37.84485601 +35.33126473 +37.35303702 +37.91916033 +38.39617293 +37.17625154 +49.75519366 +80.95162621 +57.8405433 +39.63010622 +46.25839564 +77.00435635 +63.18904268 +35.74555852 +41.4956159 +62.43719751 +62.78839485 +24.71251348 +36.07946905 +35.04045834 +86.37577766 +75.58451594 +48.05366633 +41.73299414 +52.20062472 +56.91427269 +56.1417206 +57.51754576 +48.89906727 +52.59501197 +55.69409101 +56.48832592 +52.91770246 +49.45603867 +72.238616 +52.35530826 +62.91592488 +79.13617896 +70.56516919 +76.12856946 +74.47248739 +78.18261742 +64.41282929 +68.66485602 +32.38835308 +64.13826004 +66.6092074 +73.0595814 +89.6387834 +50.16196566 +54.02498231 +60.00443466 +55.56030124 +53.81552953 +70.95621835 +89.9991751 +89.98948795 +89.71598472 +89.99676273 +71.53703283 +62.5490054 +89.63316895 +89.99109449 +89.99344546 +89.99428307 +89.997535 +89.99875201 +55.13199807 +73.32283982 +89.99254227 +54.20275297 +89.69516312 +54.15214509 +58.80400515 +52.43345741 +89.99914533 +56.87375651 +54.56642072 +67.32807983 +54.30868661 +89.99568799 +89.93013092 +89.99581042 +54.85327832 +58.99134691 +67.73580501 +55.51065441 +61.58288776 +54.68852864 +57.97411957 +89.99630979 +54.06570865 +34.68128246 +34.8257485 +31.54627895 +34.41380915 +35.97634679 +35.9325521 +34.18298001 +35.92773956 +37.65544764 +65.71911549 +48.66569874 +33.9132651 +40.33171741 +30.63358727 +47.02516241 +51.37372488 +38.0619579 +34.2603471 +43.73333008 +42.91827735 +52.28632783 +28.22915442 +3.137237565 +35.59195982 +37.51401633 +41.32542113 +71.0643722 +88.97509163 +60.97307122 +50.8249148 +54.87539569 +60.03266528 +48.96278945 +49.81309341 +51.42308608 +49.24149551 +58.54389013 +57.42525298 +65.56954023 +56.98699664 +76.24877937 +64.33629289 +64.45299334 +59.93709639 +40.66849057 +38.4470273 +82.39169035 +77.67541242 +68.56156799 +70.77168102 +77.84800348 +79.36955754 +82.46192931 +80.88957512 +70.28232127 +84.20822914 +79.4370635 +76.34145496 +83.80981725 +89.87960101 +84.43631077 +83.18450434 +72.57550265 +67.5047716 +61.58247319 +56.47191701 +55.00603144 +46.22228197 +2.234119154 +44.63928892 +43.99779107 +35.59402062 +35.66925679 +36.0194012 +17.71169784 +19.1699458 +37.13095866 +37.99575757 +38.67471976 +38.30751536 +48.16293348 +74.75247678 +46.08308445 +63.29295827 +48.63868021 +32.98577077 +45.18799452 +49.69615752 +35.71103469 +54.84677709 +40.91628683 +20.88458645 +44.9949105 +28.23196379 +29.22999358 +47.34438944 +6.567780414 +0.715736918 +33.54314609 +5.295562042 +0.656871642 +49.86533007 +49.32533443 +88.64809159 +89.70181077 +77.06194618 +89.59951742 +77.9997923 +87.21935389 +66.2856731 +80.79292876 +85.81964363 +77.01670729 +76.49805376 +85.96129486 +84.30528463 +89.04953824 +82.92961305 +83.29921306 +80.43288 +88.86382541 +88.99827358 +89.88413349 +89.00906717 +88.82430591 +85.50574133 +62.46127657 +84.94117174 +56.3680164 +56.92639881 +55.4816063 +85.01800245 +86.77148966 +52.8018196 +60.94217379 +61.17532868 +57.43374388 +56.09630875 +57.50101538 +54.13311074 +52.99290561 +57.68708442 +57.05778143 +56.22097786 +86.87845589 +57.02970398 +81.32755072 +72.60744191 +53.89208981 +43.39920843 +62.08339944 +50.64591046 +1.615563137 +73.21776491 +46.13961502 +63.81215029 +65.33995145 +81.34254067 +89.91780891 +89.99925948 +71.07759827 +89.56376225 +87.9049741 +84.13469431 +14.31634056 +87.94352677 +88.94199467 +85.48284872 +89.99972768 +89.09611581 +89.47192001 +21.10113625 +89.87071351 +89.99980774 +89.35541915 +89.25629126 +90 +89.99947084 +20.79740279 +89.99532867 +33.3396129 +28.62834576 +22.62036489 +14.74815918 +21.63396037 +89.40883348 +22.87352596 +89.62915127 +23.54212938 +82.30002997 +89.99927261 +89.90085408 +34.72282551 +89.99728398 +71.6923299 +20.04142462 +89.64855654 +89.40024141 +89.99127987 +89.25523529 +89.51369421 +8.923997766 +88.67762081 +88.75837389 +90 +84.7713984 +88.30808485 +89.6602879 +27.8815699 +87.61349611 +90 +89.99149328 +22.89380436 +23.18662227 +21.61884857 +89.69038993 +19.92653322 +85.50564569 +77.51545955 +89.98770038 +60.69412575 +40.92186332 +53.6599333 +54.44096243 +67.52768873 +25.7468759 +42.36690045 +25.2571941 +57.52264631 +55.76493285 +52.14230067 +64.9802074 +51.74743125 +57.02626278 +87.70954658 +56.90655336 +37.6983925 +0.21582616 +77.46951333 +89.64099063 +78.59104593 +57.8728031 +79.40790289 +86.88576368 +86.05962088 +85.80856619 +68.12386079 +82.52475073 +76.23116159 +89.73513432 +85.49619564 +80.21811502 +89.16574242 +82.61446846 +67.52711408 +88.56260501 +81.43311037 +69.98831904 +47.43402729 +80.87647102 +61.4035347 +88.6013249 +83.81776202 +59.63579973 +59.12128759 +63.31118768 +54.23571794 +53.59253202 +68.83935464 +57.50875979 +54.98776415 +43.64031267 +56.39557753 +59.58749475 +66.7866308 +62.01665674 +58.13004471 +45.49227155 +62.77864494 +86.52740128 +72.2655869 +79.68851939 +89.91267154 +89.73896877 +89.32559916 +86.5425679 +89.86273806 +74.02454117 +88.21395339 +86.44534755 +69.11254149 +40.59667384 +68.45544732 +79.83906389 +77.37567891 +67.09348043 +60.74258667 +54.60726218 +54.51794795 +61.93050525 +49.35206164 +56.42594992 +52.58552223 +62.27601504 +54.07351833 +44.14049115 +55.21133604 +53.92663375 +54.142784 +71.52846847 +67.68663131 +45.4602368 +76.82289962 +71.90898821 +75.86511491 +63.15430284 +42.67119809 +19.4373125 +0.463603641 +0.770193967 +17.88655407 +36.05456261 +37.35557246 +34.41291846 +37.23558981 +15.78177404 +64.99452384 +46.24905688 +49.38652894 +0.425527659 +14.73157228 +23.87562954 +6.287198687 +0.326799455 +40.6901708 +69.6626586 +46.55684973 +34.64547314 +44.5230242 +35.22850049 +37.06076867 +34.58212728 +34.900997 +18.97779426 +45.55533467 +48.51624211 +32.68605098 +53.96069314 +17.65912819 +39.69151938 +84.59552391 +72.94927466 +62.5563151 +60.45044276 +48.85696294 +55.70894834 +47.41503498 +56.04234358 +59.71851202 +56.08655089 +57.30483505 +44.80946294 +59.28065836 +58.55364457 +63.96418526 +54.2454979 +39.40327293 +39.16133505 +46.55746978 +85.79303051 +45.85978851 +34.03799692 +36.81410876 +1.366664638 +44.20451445 +37.58303565 +36.86796988 +71.41144575 +44.78208315 +46.76113735 +52.09273029 +22.19469362 +58.16716664 +46.42907045 +58.55570091 +38.04284166 +35.81638229 +38.36343897 +36.17809174 +18.78278856 +36.3195332 +49.19639792 +44.86819986 +34.76893504 +34.06080189 +20.26013864 +20.01799469 +37.36700296 +34.97158473 +44.36525713 +75.5826493 +48.78151591 +71.69804037 +37.758814 +49.17748072 +48.84006607 +50.17718321 +49.50305053 +60.69297584 +48.32099429 +44.66198634 +52.36832528 +2.715739528 +62.88856785 +51.05630932 +45.21077122 +35.87981424 +35.20175245 +45.43967115 +37.53401813 +37.71302641 +34.29508293 +24.30900928 +36.81988018 +36.74948091 +56.0504355 +67.00912562 +47.56304046 +54.62799369 +3.786019908 +35.94043893 +23.23749115 +5.496873538 +37.62563898 +52.18267457 +55.40052603 +40.39930349 +47.38375079 +59.56828382 +54.30831487 +67.05654878 +53.9172933 +46.19569655 +57.04493415 +56.31807383 +61.09387313 +57.54029582 +71.54862072 +69.06902728 +48.60593381 +53.95982796 +56.38714391 +36.69628605 +71.8823382 +74.05263245 +36.16185062 +49.94192621 +51.13339867 +38.43611215 +36.04996498 +20.31638729 +23.78356859 +33.65116596 +35.23246906 +20.45442815 +18.46332952 +37.87525475 +58.0343411 +45.51035134 +41.5054701 +49.13244961 +50.76188087 +18.0708254 +37.1052922 +18.31282586 +38.74201878 +36.42875242 +0.160708758 +1.775061683 +55.03746297 +23.94699629 +44.33196353 +56.58841233 +55.48146137 +0.818948769 +55.98405641 +37.90706506 +62.81594071 +45.12966405 +41.18764978 +54.2550443 +54.29171004 +56.68707679 +36.51291541 +0.345477527 +1.540977021 +1.006740649 +50.296633 +60.74435856 +50.91625472 +49.118742 +49.83000901 +49.52804317 +46.74470482 +56.13666232 +54.99260936 +76.04420483 +59.18112174 +66.5277012 +38.97328264 +31.01161 +79.29970005 +55.02126468 +44.30566332 +31.6182572 +46.59365942 +0.555214653 +26.2401143 +36.84698717 +36.3734779 +36.63552292 +13.15196119 +36.626483 +23.5671105 +46.02479347 +48.01642991 +53.03709762 +41.60544432 +51.63852513 +37.41362106 +42.24702366 +53.56202936 +56.20987252 +35.20566982 +38.67026409 +36.77990516 +14.59316674 +37.06949846 +21.7587095 +32.78936702 +36.06745789 +52.06705622 +49.53976737 +54.40881142 +53.33239751 +54.43332342 +36.57539803 +33.41665709 +29.71109557 +1.494560836 +1.518635168 +78.98507711 +89.6444619 +85.71307807 +83.64195085 +76.06685824 +84.71097524 +83.38803682 +86.39752701 +87.22305344 +86.4907393 +81.73773102 +83.23687874 +87.7870121 +87.21605476 +86.21567884 +87.27279603 +85.42198768 +86.46339964 +75.79348286 +87.00665848 +85.92766615 +82.13070008 +84.13931178 +74.97407792 +85.51337183 +87.07314747 +66.96720787 +61.1740822 +57.53482728 +7.953189763 +48.36368096 +48.61501442 +46.25209295 +64.30088675 +54.91072693 +79.56308326 +59.21452258 +59.0428612 +44.03557961 +49.42543192 +59.16529498 +14.83677013 +31.22242615 +37.14741051 +26.21008856 +1.143125288 +32.80538491 +42.28970874 +35.63509318 +34.58218979 +33.85197725 +46.09378018 +34.21762177 +45.00901682 +31.08907953 +49.07456995 +35.11998462 +19.98649461 +11.86882135 +55.89729147 +70.79305212 +84.47412402 +72.80657541 +82.89116037 +81.69962664 +80.3801038 +80.03439734 +80.40426572 +89.65698482 +82.81039771 +84.68060044 +77.41644678 +83.08384724 +81.93754505 +83.49514783 +83.56038799 +83.86045743 +81.36711836 +87.80147105 +84.25971039 +89.49637863 +89.21525125 +77.76320419 +70.37692662 +83.83471681 +79.8888898 +77.00177558 +57.16410424 +61.26678714 +89.98623144 +85.95701488 +60.55453138 +65.27318661 +89.44117378 +60.8923804 +73.09567423 +47.82257877 +61.14329481 +61.71372481 +61.40230297 +61.52036725 +80.51348272 +84.15245113 +79.68409247 +69.30409642 +68.85737745 +37.74071773 +37.1207095 +66.37210224 +83.75356494 +77.17630534 +56.29565856 +40.9296927 +37.85430201 +35.14997649 +0.030747142 +0.005461412 +36.25074458 +15.34238231 +37.91643973 +63.69668168 +54.79826111 +47.69067063 +49.99283682 +52.01530896 +39.10856329 +38.09926335 +16.68370881 +40.20369073 +0.020725289 +48.98737114 +0.06391324 +0.041832476 +44.37472241 +35.25407084 +35.6809586 +35.90497723 +37.54985559 +54.78731962 +53.56623593 +0.006018505 +9.899180873 +36.21739735 +23.10812195 +0.010182074 +34.22551946 +42.83774562 +0.012074447 +61.69256259 +41.58927356 +89.74011723 +82.80289088 +74.97764494 +81.56007932 +89.10890536 +86.77003404 +89.52091143 +87.03216024 +85.1759873 +83.28332703 +81.32981002 +47.2538692 +0.018588457 +8.92168541 +89.99788609 +89.99813957 +89.99726901 +88.86238197 +89.99435633 +89.99941852 +89.98829082 +90 +89.99490693 +89.99187807 +89.9931714 +87.87263109 +82.28819104 +89.9963066 +90 +89.98447299 +89.9996376 +89.99487423 +89.99866832 +62.84871322 +53.37138928 +59.17943414 +56.4430334 +50.67032078 +58.6553775 +63.08578932 +70.38110096 +61.01194653 +62.50094277 +64.08402638 +53.16177701 +45.81361505 +46.97241152 +35.69517308 +22.20216914 +35.4106675 +38.17163798 +36.47069061 +36.82752528 +18.80044808 +37.3317453 +37.85816953 +35.78912168 +37.59315854 +64.85487033 +56.06541435 +73.16141687 +55.03289407 +36.52079337 +22.11083383 +10.65182975 +60.17204339 +36.33182594 +4.422121898 +30.85168421 +54.20560196 +17.30666394 +41.43722907 +33.41543389 +31.46165756 +35.4210063 +36.61472334 +42.90153689 +33.07883251 +31.56651183 +43.05582181 +49.09814018 +49.15771343 +51.43089643 +36.94073935 +0.305953887 +86.5056992 +76.72991576 +46.37939016 +64.8509228 +61.4213865 +66.46455792 +60.85318512 +30.08308116 +58.93836048 +13.4851779 +60.56161071 +49.50929308 +59.45953992 +62.2433 +63.0080882 +59.05848384 +58.9277906 +62.11796429 +62.73460256 +76.59055155 +76.54498621 +89.9509389 +66.97681775 +83.04127691 +73.28398569 +62.78420497 +75.38441033 +72.83657997 +57.11360624 +62.23190504 +82.39956878 +62.02434383 +76.5529835 +89.7420787 +65.97177477 +89.94646267 +12.42568945 +88.94867523 +44.19767628 +33.21839776 +2.533955587 +37.75147433 +38.26989925 +38.3658099 +35.70972912 +35.79207145 +37.9675121 +37.9908014 +37.16825452 +37.7846482 +39.11059415 +58.35662158 +57.51555889 +62.9743398 +82.96000308 +54.7402724 +52.07134474 +45.82536578 +46.2701738 +63.82628084 +55.27861067 +41.97963642 +53.32050026 +55.96755603 +23.80888984 +38.11340122 +0.085055456 +0.013573698 +44.39485218 +73.3890385 +58.90517969 +61.98973127 +39.55662911 +36.8183076 +0.217564222 +49.52559454 +23.32609451 +36.66351858 +36.4807977 +37.15402801 +36.58156479 +37.33678365 +36.59791832 +37.94700572 +34.51333007 +53.6873308 +37.65789492 +49.26427052 +64.0509379 +61.3650675 +55.11206348 +59.74040962 +0.110428882 +23.05514431 +37.08388215 +36.94265654 +36.67580414 +0.801898994 +43.37766286 +89.91817902 +60.31002561 +50.94776239 +67.447377 +37.75405914 +49.28826495 +61.06845064 +68.25224675 +52.9173542 +51.64742946 +52.65560153 +52.31504798 +52.25672003 +52.94138181 +52.23170786 +51.57390152 +50.40326637 +52.88789304 +51.99616436 +52.91806315 +52.42659679 +53.55988782 +52.62437381 +52.80172541 +65.49923791 +68.98286467 +65.44976487 +66.12334398 +61.86671375 +63.46011971 +62.0318895 +60.97470731 +72.9223104 +60.4529195 +68.16080452 +71.13809356 +49.49332001 +62.11933025 +51.9492095 +36.10550419 +54.78513331 +23.82735727 +69.73760578 +76.22211153 +41.17992539 +67.26098128 +79.4544609 +75.10257848 +73.32706266 +70.06339446 +75.17430245 +74.54344756 +77.23935189 +78.57880184 +74.19958051 +77.05545895 +77.12362832 +85.0881887 +76.87195605 +82.63696099 +79.09612173 +75.7901698 +77.15886742 +81.25581721 +67.68949832 +72.10378001 +85.47575665 +86.09577731 +85.53385626 +59.72071634 +52.44321504 +55.00929813 +66.01650155 +47.74966165 +43.24752089 +51.35008388 +62.55516249 +56.51617753 +55.67605982 +48.79054423 +55.73748128 +48.64903972 +56.14632619 +65.22936261 +56.65654082 +53.41531835 +54.86209676 +46.64876591 +55.8931754 +49.41340974 +67.36125678 +63.98862241 +50.10720195 +50.93117494 +52.05509712 +27.21650406 +24.10181826 +21.3564318 +36.94672882 +38.24903104 +34.94885677 +36.86436067 +35.01205562 +38.28647609 +36.70100343 +36.99659897 +57.28046495 +43.00130464 +43.44190144 +50.45064817 +4.489304301 +53.24996167 +26.58333815 +39.09899845 +0.209401746 +59.29055797 +46.86744431 +47.42339725 +51.7324662 +30.92235285 +41.93670222 +37.49296677 +37.28164211 +36.91190115 +37.89713869 +37.7687962 +37.72052749 +37.10955674 +72.00528036 +63.11570191 +54.37390641 +36.97644662 +35.41123114 +33.29033699 +31.82837152 +24.35226444 +58.05818873 +48.82143419 +55.81071608 +57.09404634 +58.43127905 +47.60752708 +61.04018671 +57.41254898 +60.86688629 +71.97572817 +75.75130301 +74.01161935 +76.6332702 +55.80534308 +62.69175163 +51.70916297 +30.6513447 +53.14581362 +66.88939835 +50.94528005 +56.29163096 +48.71408496 +73.23973683 +43.57476242 +50.73870439 +58.22869178 +53.25779846 +52.28441945 +52.37173469 +64.88642918 +67.31875845 +61.25072171 +53.42685285 +64.12085787 +52.24191856 +32.67241762 +39.61200812 +36.52675007 +56.10412647 +67.06379991 +88.013401 +54.5912245 +12.42842875 +45.29277102 +36.51344319 +19.860997 +43.32534078 +35.37491618 +37.43390932 +35.7158438 +35.5162779 +37.50885794 +35.63557963 +38.7514111 +17.26825792 +36.77973221 +36.19342394 +52.52758621 +46.88456021 +53.60680317 +9.463868528 +0.031921702 +18.56805343 +47.6184572 +82.54343238 +61.30395712 +50.7106824 +65.8051893 +46.11499896 +53.64073615 +58.99941323 +51.9056796 +53.53936247 +55.10313179 +52.91792782 +55.47664231 +68.43477823 +71.09220398 +59.19348553 +53.96989455 +54.19091526 +70.33884838 +43.94573911 +29.90001866 +70.24366519 +70.71567338 +66.82009606 +75.69246585 +89.99030457 +88.79342862 +89.97626336 +89.97737705 +89.94991333 +89.75612172 +89.88220021 +89.99604155 +89.98258817 +89.98942796 +89.94163951 +89.89525536 +89.98731465 +81.21357191 +89.99006207 +89.99000539 +89.9942216 +89.9948105 +80.83803395 +89.91352923 +89.99942249 +89.87977598 +72.99392221 +69.13813016 +49.02995205 +66.26699749 +56.60141039 +63.34951921 +73.08937911 +61.11585025 +3.987104009 +15.50253483 +67.58980273 +0.00449822 +27.86249052 +79.39167545 +24.30393463 +45.60655396 +57.15036766 +48.10128113 +53.02396121 +75.94427702 +53.82074351 +54.47796868 +36.90449463 +55.51371506 +35.60656022 +21.93384196 +37.92245607 +55.56210352 +37.20481264 +56.22197334 +36.19081696 +53.15729114 +60.28920648 +45.93912133 +60.95906738 +46.60887593 +69.86184162 +60.02399147 +66.25258908 +55.05504775 +63.81573588 +54.83558942 +73.41940933 +58.6707574 +11.08868169 +59.20644666 +30.71636323 +6.369950345 +49.63800414 +72.70433902 +56.92007083 +72.25916922 +71.31384266 +59.83456817 +60.22902865 +46.50468407 +49.6331424 +39.73791336 +25.71877926 +31.69108819 +49.88912936 +47.67372733 +50.4301432 +48.35777527 +49.38945702 +47.93055019 +62.79853427 +60.90498772 +38.20974579 +55.22038136 +56.97466099 +57.06215013 +58.69315879 +61.01561729 +60.5346771 +41.2123976 +42.97788915 +52.64489735 +54.11025885 +54.48849873 +54.77336439 +55.60844646 +63.69755938 +65.17063399 +60.61078309 +67.88251937 +53.73038643 +55.1919953 +34.04289257 +58.94136146 +1.874737501 +88.52193909 +74.17332036 +76.67525671 +74.46594524 +61.47440696 +56.68939827 +45.69417014 +54.10929119 +54.03060697 +45.09036262 +53.48840822 +53.41440563 +65.06858964 +35.19280941 +20.24327562 +89.19629646 +31.58405085 +37.22564838 +20.19253212 +1.31162856 +34.29800661 +33.25089846 +35.51419854 +36.0800762 +49.15849657 +33.64671611 +53.31515154 +45.64251619 +1.471305649 +44.15237404 +46.4146108 +3.427029158 +0.194818208 +63.25443662 +20.74999848 +35.5541117 +44.76866472 +34.05518597 +46.58832032 +0.049915389 +37.21093802 +35.94620243 +49.00886948 +45.67250579 +46.66347112 +52.86101479 +63.62908286 +51.8436024 +44.23842854 +48.53287664 +41.23023446 +57.95837525 +58.16994406 +70.63465507 +56.43504568 +54.09107323 +56.44323733 +46.09981677 +56.52833886 +55.94510907 +72.87069439 +58.06065817 +62.54975456 +65.61735917 +66.79776023 +74.90034056 +57.87167756 +55.33755795 +55.8182908 +56.59742272 +38.44437568 +86.44546041 +67.75066902 +68.22681779 +58.70403302 +58.92204611 +67.51811263 +62.68596995 +66.19386933 +63.58629326 +66.68687472 +73.14512642 +67.40755797 +66.2788172 +58.60827298 +49.0015419 +72.31092134 +68.15477189 +68.486237 +52.51511326 +56.08031852 +54.76882307 +49.17662434 +57.90713723 +62.66548989 +59.67752087 +59.50475883 +68.10341634 +82.58477842 +87.16977183 +81.46076444 +77.05316859 +61.40093294 +75.02870628 +55.50266584 +78.71576431 +55.11072189 +35.45436828 +34.97144866 +35.50854233 +35.75347414 +21.09756748 +36.70594791 +37.02582475 +54.8789779 +30.97782977 +52.73862485 +36.61893052 +20.28421201 +3.072662114 +33.88854375 +37.01264033 +33.44330082 +33.24849241 +28.15298852 +33.19195042 +34.16526067 +36.81073728 +45.35071501 +33.08876192 +49.28946487 +52.95012899 +32.75493844 +42.67319224 +3.244810303 +38.28849598 +74.13271091 +89.44955013 +62.17317558 +52.93726093 +58.3033849 +62.92737768 +53.45999956 +56.65401573 +59.22607811 +65.32722415 +48.65544876 +40.9249701 +71.7888766 +62.65173137 +75.03723826 +59.08530388 +64.88357998 +54.91799068 +56.3464784 +53.46081312 +51.15190492 +51.43402874 +52.75305701 +39.97668006 +48.3798103 +50.18348929 +50.9184084 +43.0118708 +50.83390027 +56.30364435 +47.38756006 +48.83142306 +37.92568277 +29.07648362 +71.44734734 +60.92069375 +33.20192447 +27.45922738 +41.61491021 +35.45585517 +36.11375519 +36.03492925 +44.7053034 +47.62754755 +52.10771447 +31.3161802 +35.53886 +18.70630092 +53.57992022 +46.49113357 +12.9201807 +0.646948906 +83.62998003 +51.24911023 +48.8430428 +63.42708572 +54.99166423 +26.2359211 +42.60975454 +43.70173533 +46.03860306 +47.23307007 +46.9008748 +58.2963808 +53.43522783 +57.02112127 +77.9099085 +21.31996129 +29.78756985 +26.45725882 +0.267713088 +63.04070526 +56.67962787 +13.31886837 +33.89942492 +40.49403951 +31.63178534 +33.02170311 +7.880729299 +4.644599432 +35.28902143 +36.00586164 +51.6080865 +29.42089303 +43.90474632 +42.25830114 +34.67588684 +43.77841709 +0.430146019 +0.471441037 +31.83351561 +50.16744644 +51.42491882 +44.72036598 +47.40276881 +55.28034028 +24.34579899 +34.12652137 +36.08909608 +35.47254736 +36.98396016 +37.77156037 +67.34654847 +45.85516673 +54.79156236 +36.4705395 +43.84235272 +0.405808667 +38.41211353 +0.868335403 +41.87389543 +51.92764503 +54.89842701 +51.09325733 +31.09441244 +19.94621572 +48.97632486 +50.78129273 +46.95815078 +49.86784209 +39.46140359 +51.10893806 +61.10187323 +62.46679555 +68.30697661 +49.67882898 +48.95774968 +25.58804943 +33.42466173 +28.96691072 +52.12719213 +64.11464057 +60.80851331 +87.14895674 +44.69690547 +44.20823059 +42.25383783 +63.73871943 +44.69842044 +44.59953496 +45.7746479 +44.19529184 +45.04455671 +89.96063817 +65.60198046 +61.797192 +63.16790691 +63.72405244 +50.64455471 +82.8267941 +0.005222232 +43.99301815 +46.71362539 +89.42316708 +42.34606909 +36.6239388 +37.26564735 +54.21157677 +53.88341111 +0 +35.42328843 +45.02391808 +0.009812195 +33.24816857 +37.44296956 +43.46495537 +0.008168378 +38.96298527 +38.88154763 +54.73380995 +46.86981972 +50.71809467 +0.004161032 +0.004593962 +35.24111407 +36.11854611 +0.009514474 +34.01847663 +36.41032826 +36.44469674 +36.91797655 +35.57991431 +35.85271304 +55.32093087 +36.44326584 +60.67758811 +64.12280415 +52.94886464 +44.07581608 +33.36229809 +7.902878046 +54.13777059 +44.65129816 +32.7991095 +0.005061378 +0.003710709 +0.025550448 +0 +37.24002025 +36.03007143 +37.92159919 +37.93553975 +43.94472879 +42.99019961 +43.04619619 +32.71882187 +17.64916924 +0.007020645 +44.84086598 +45.60260578 +58.41807959 +56.54643364 +51.23639868 +48.58474098 +49.77579979 +42.51039138 +66.56290209 +54.44842443 +48.14069584 +46.8020907 +54.47678767 +55.21445667 +54.38109562 +56.01710881 +55.32012976 +77.07840231 +57.82536982 +70.84334062 +69.90249941 +72.47692051 +57.7784225 +46.64866904 +59.87595017 +0 +0.004519948 +39.0973932 +38.62261451 +41.03497947 +38.86649032 +62.29769895 +40.42506432 +46.79386677 +65.46584647 +54.35058118 +64.36527133 +35.83350632 +29.63451746 +55.643326 +44.77103922 +69.9880264 +47.28639221 +54.58314248 +53.58465886 +52.93363438 +53.55715184 +52.30400598 +55.35504085 +55.17004154 +53.58197415 +53.75830903 +65.05746141 +65.63262539 +73.45764966 +67.37034937 +64.0573109 +65.8510102 +57.59579394 +73.23575402 +48.62584051 +54.76854895 +39.19401245 +52.55969563 +38.85670547 +36.0683177 +1.21047696 +36.52307866 +35.06304166 +34.58372473 +33.61068395 +57.40234503 +58.29029505 +27.98349855 +46.27992179 +58.96619664 +47.61301017 +50.6550859 +33.33612506 +42.27795511 +0.02239638 +4.684836175 +56.7705276 +23.26392615 +26.41540114 +45.38789186 +55.53536309 +54.07506151 +54.11445365 +56.17540094 +52.58428838 +57.45509085 +65.83427349 +86.63129548 +56.9471648 +74.05061025 +86.83712215 +60.47146391 +89.96102666 +53.98721749 +47.85646741 +39.41522218 +67.27900317 +56.06309278 +47.82336953 +50.70548129 +0.009613755 +0.004848044 +0.00950139 +33.21493123 +38.2122346 +37.27607608 +38.63886824 +37.87236197 +61.54055576 +60.34153388 +36.10030323 +65.19993773 +35.4844503 +42.05018413 +0.027727703 +0 +44.09378829 +53.4424699 +40.04191097 +49.22188761 +52.781801 +51.16808511 +43.70560201 +18.67089618 +2.694139923 +6.233553331 +0.024436423 +28.72304359 +58.3559417 +0.177712594 +38.91791874 +31.61629151 +40.63582258 +44.03349788 +37.62175698 +32.234243 +46.44986437 +44.11157287 +35.67625236 +44.81728409 +35.93020178 +45.5977189 +46.37737525 +31.60147328 +35.80337673 +0.035145993 +35.6943395 +34.08536577 +47.49970451 +45.54943319 +36.87069171 +37.72758867 +34.8961866 +44.52947487 +35.58800418 +46.70167437 +36.05963572 +58.27758459 +52.56437857 +59.21186809 +59.17326273 +55.58182461 +54.66868047 +47.02287362 +58.74339987 +54.14010326 +42.75798089 +43.27659981 +65.30358246 +66.70706689 +60.95972845 +64.35203026 +65.26750246 +63.39089658 +33.5417919 +66.46652814 +58.75032136 +32.08150479 +82.68841188 +53.60846743 +49.00587886 +41.26745677 +44.06816301 +30.68967902 +53.04497958 +77.59807813 +44.69207542 +61.1304384 +22.0465631 +34.37944678 +37.9350684 +33.50789954 +36.30803804 +34.64048246 +31.26691468 +0.018737974 +53.21345231 +0.026974426 +3.762683452 +0.000343487 +0.03256516 +40.17304093 +41.67587158 +39.8342409 +63.37469813 +50.19765602 +60.87032752 +40.49214973 +38.29938338 +58.72846407 +89.99392344 +48.13783253 +58.46320686 +51.10860933 +23.72669171 +0.012511671 +56.31456524 +0.544117754 +35.13121133 +45.70838812 +45.25420844 +43.59468571 +37.1806003 +36.64770408 +45.09857769 +51.23006162 +38.42939056 +48.24370331 +49.05608943 +49.26715999 +55.11021232 +54.73473174 +64.346689 +64.84265443 +68.54447266 +67.69896993 +81.88200932 +36.84075417 +33.33191822 +83.14595974 +51.79775271 +64.58520488 +65.84445557 +73.74333597 +64.33948747 +73.42426156 +39.03529285 +26.57675149 +35.17656349 +0.008563194 +56.29777869 +50.14039396 +62.08707291 +34.56311274 +57.24577996 +55.05281665 +56.53262856 +54.85619577 +53.41820598 +51.67719546 +54.84784311 +80.2104874 +89.99686799 +89.96074125 +89.93386107 +70.39064062 +39.4958862 +0.037678337 +89.60691456 +60.95528533 +77.88314667 +78.312406 +58.66771792 +60.43112844 +74.09684574 +47.44344924 +0.124728777 +32.50770779 +47.0043926 +47.50106608 +62.2160699 +70.63903703 +71.14312074 +65.89414984 +70.13644397 +59.15016855 +44.52931884 +29.09659681 +39.65380125 +38.97617585 +68.1760323 +0.021585167 +24.02890246 +0.565492882 +0.013854052 +0.008607077 +0.035364194 +0.019246955 +0.035322772 +0.017316769 +0.031706042 +0.005103462 +50.59534771 +44.21011125 +0.013878158 +43.39340044 +0.01826206 +22.65887801 +0.040701618 +0.48303345 +39.1002171 +0.0389862 +22.77795524 +0.020265081 +25.80672436 +29.19002203 +26.71582715 +30.12710612 +30.25529722 +41.77782118 +42.87964782 +58.61571218 +39.75640022 +50.89725279 +47.51089864 +47.534981 +43.08075625 +0.063168746 +0.004619109 +0.036653358 +26.59386312 +54.73705586 +44.49388896 +34.76761757 +11.23204882 +33.66658977 +33.32477794 +0.999661517 +36.21536004 +35.62683893 +35.23403471 +31.16307925 +52.29427028 +10.89582119 +0.279376206 +3.243370463 +71.86178401 +56.46218232 +58.10737285 +45.90907591 +45.83707712 +37.67266278 +36.90784549 +46.04576753 +21.04180536 +37.99798589 +38.27084055 +25.06356685 +49.31557446 +13.25782062 +45.14706821 +37.77428289 +0.208797836 +39.89716633 +45.9041999 +49.02599318 +37.04953749 +46.46684831 +46.03952691 +49.43981106 +57.09703386 +53.95835164 +58.76239931 +59.13278412 +54.56921742 +64.25974011 +76.92790561 +66.63601857 +82.13045161 +71.71665785 +3.683442538 +2.06617223 +73.66351303 +68.24915365 +73.70322163 +41.30039196 +45.72029154 +18.90339637 +17.65920302 +36.5884732 +34.70096871 +35.6628411 +31.99008503 +35.14716451 +19.89366097 +36.37733802 +36.02454729 +34.67431341 +51.45094103 +55.60500609 +47.52847194 +41.87863333 +34.71295571 +50.67116682 +52.6033329 +49.15497613 +35.50618364 +35.83579966 +35.16972379 +51.45223152 +17.14915031 +11.32381416 +33.66275878 +50.97431692 +52.75766254 +54.65478304 +42.78748828 +42.83025423 +64.79080186 +40.67366273 +66.86179253 +53.09064268 +34.21677977 +34.3051364 +5.652010273 +0.321003442 +54.50261617 +32.21010404 +89.42026562 +12.3899451 +16.08547136 +20.7744031 +21.0325248 +34.88000534 +35.13484776 +35.55841242 +36.35812976 +36.04407564 +21.52351988 +36.37905892 +37.53463121 +35.83595878 +39.41208162 +75.76891779 +42.38951423 +46.62860458 +40.82696525 +61.18330941 +31.45771909 +1.609239344 +4.577832524 +45.22588228 +55.42592751 +44.10293146 +61.01847233 +50.60252296 +47.20966237 +54.06097387 +46.9429436 +50.26148879 +49.31604242 +46.80814717 +46.08151353 +40.86483058 +45.48254708 +49.84362767 +47.64721293 +66.14677956 +50.71270231 +55.11157707 +62.42049097 +57.66926954 +79.15035856 +47.62605938 +49.74979944 +66.54291599 +76.62004942 +80.69283231 +54.39719179 +46.03862392 +43.45790035 +59.79577383 +32.53969912 +32.42269185 +51.74311845 +37.77033048 +0.030018508 +0.071435965 +35.67706413 +36.51729373 +56.11766457 +36.51722462 +38.07573447 +37.1610727 +36.91677546 +33.63946434 +37.73116864 +55.53314204 +55.08973677 +48.59112849 +41.8129635 +50.54005638 +50.67396194 +37.69035894 +38.21684724 +36.65537506 +45.68388289 +33.15769135 +4.267614801 +4.96167713 +89.12733834 +23.30007136 +20.69510835 +38.93317956 +38.64963255 +38.28993017 +39.27274463 +40.94531218 +53.81510639 +44.40685225 +62.58288131 +59.49519625 +51.77589561 +71.45638258 +72.30424381 +43.59141515 +61.00734122 +23.04161952 +54.86944568 +41.18943119 +40.68875371 +59.88235074 +70.75839735 +77.24098588 +62.76881929 +54.75210743 +52.4406552 +50.90202863 +55.5570749 +54.06228826 +44.8129321 +52.92222831 +57.10824079 +52.59159617 +54.46060041 +70.58027442 +71.05219504 +73.45165129 +63.83070672 +44.97896177 +54.14862613 +42.36703216 +37.84324293 +34.69331616 +60.45377651 +50.44175107 +47.8874647 +38.64436835 +47.86022827 +47.26364732 +47.7224806 +50.20915995 +56.89779945 +74.0266535 +57.79514485 +41.90121176 +67.29676529 +67.22960942 +71.57196556 +52.69867703 +73.65137364 +60.28031371 +40.71952294 +54.05186304 +47.03965825 +43.54720331 +41.83966227 +24.45748069 +28.17106581 +63.2543476 +82.25862413 +40.135731 +33.53609479 +46.89916199 +55.81535058 +53.02811923 +55.12736511 +54.57857399 +59.7410094 +59.81323248 +57.9951886 +69.77298573 +59.75404689 +61.55576166 +68.58352206 +66.2926473 +58.33147576 +53.40631837 +72.60757205 +66.82726485 +47.87558771 +88.8521562 +59.35283919 +57.82192952 +56.18744739 +54.75928004 +41.81478514 +56.85354987 +83.83662435 +70.10072086 +70.36537625 +73.83535389 +78.19478297 +69.85640876 +76.2418907 +41.12230929 +53.07948167 +48.1423447 +54.95362289 +50.1836698 +47.04418353 +53.59938686 +61.14528045 +57.33677873 +68.93505481 +56.63924538 +69.07774451 +74.42307289 +58.43060861 +65.26671772 +41.54647223 +44.07912182 +42.19134157 +9.67081591 +52.67031633 +87.99627257 +87.35807619 +66.39357177 +36.29065368 +37.00704402 +33.87707155 +36.36802685 +0 +0.00862744 +35.7404992 +34.26495625 +38.91284457 +58.71532517 +33.61947611 +36.58693646 +35.54993618 +39.02132965 +35.96254629 +43.66087767 +63.45847709 +41.63112914 +42.61454522 +58.87055707 +38.35134249 +53.63838976 +61.83848216 +31.7722801 +49.12821601 +57.20929866 +0 +33.41297096 +44.93247896 +0.009256431 +0.024788678 +0 +66.65209041 +88.86914155 +85.03360407 +51.35039038 +23.17068045 +32.38014143 +70.2395483 +50.33678576 +47.29745886 +52.15844891 +80.78951506 +63.08321835 +73.83891924 +42.54775668 +74.9690245 +76.87642519 +89.98344088 +89.7230318 +84.25460963 +89.83244892 +89.32598319 +89.98687241 +89.99869079 +89.98490401 +89.98553766 +89.99453417 +89.99835877 +89.97706958 +89.9956878 +89.99898178 +89.99279412 +89.99914919 +89.96165233 +87.93869272 +40.09421534 +55.13830362 +27.04966518 +55.86458282 +61.24952652 +52.10698511 +57.17041769 +65.47040315 +43.128993 +30.13519636 +46.33349957 +55.33049924 +0 +35.80799157 +38.18780866 +36.83928472 +36.60270328 +0.012358866 +36.66707624 +50.97153654 +30.94843432 +46.19763351 +0 +0 +0 +0.045677598 +36.96231979 +42.93645922 +51.87191684 +0.024194178 +34.23435691 +35.34978789 +34.2716485 +35.21645346 +36.93112966 +55.32829822 +44.87396354 +47.37582541 +62.46246068 +52.54873645 +49.87880593 +0 +0 +35.28526605 +48.659249 +76.51072664 +61.25150142 +63.93098793 +67.09787349 +61.39295749 +86.82299411 +85.02529937 +71.68848007 +58.0796158 +60.09871486 +67.56953449 +74.02427082 +0.007652749 +88.54504507 +27.39713607 +47.85075613 +37.96499391 +43.70745761 +0.058966184 +0.009554388 +0.003213516 +0.261822782 +0.017609943 +10.47789415 +11.1438668 +39.67870019 +36.55576642 +9.691550074 +13.76451229 +15.81630374 +52.43565092 +40.00811852 +13.82674308 +16.87934393 +0.009240772 +0.350665986 +38.63349532 +23.52332348 +16.61807985 +38.18834093 +38.93640384 +62.56417133 +16.5757745 +68.45920733 +63.50945935 +22.22791462 +52.85856382 +64.78144938 +36.03632886 +39.43128082 +39.82497713 +0 +0.022061959 +0.004835606 +89.94982694 +42.16194582 +57.25644117 +47.55401333 +89.99115832 +89.99219384 +89.99514849 +89.97684286 +47.3605336 +46.32482586 +48.23900055 +50.3536647 +45.39510168 +50.18662647 +46.35266273 +76.26605011 +44.33149964 +55.6135217 +83.33739365 +44.87236499 +43.25140131 +58.53755801 +68.90368948 +89.98797598 +89.9962153 +89.77867502 +36.55645646 +58.6853472 +60.13818559 +30.34549063 +58.77252431 +58.27072308 +60.34880442 +51.99489412 +62.88878052 +67.51830972 +59.32719822 +83.4406735 +66.46075148 +63.90463088 +89.39636313 +59.41064409 +76.93498537 +83.63817295 +66.32838829 +51.33304079 +75.92534972 +85.95881164 +83.30153089 +0.00435628 +0.004642664 +0.007316731 +34.75868334 +33.95038649 +34.85513345 +0 +33.48263732 +54.31626919 +46.46372675 +35.2198545 +41.66937484 +42.75760704 +53.05603088 +61.55491732 +53.83493933 +50.16150897 +35.63351864 +21.82082719 +35.56115052 +0.004819386 +56.10562344 +0 +36.30044281 +0.048875932 +37.43972745 +33.43019159 +0.021792934 +53.31930684 +37.40011492 +0 +37.8299836 +0.017371715 +0.01917295 +69.6007615 +64.17268139 +70.29772603 +62.49292069 +53.36771668 +42.27816946 +0 +0 +33.81696346 +35.04296686 +0 +50.74595576 +65.06505209 +37.41654509 +32.25435717 +52.9343799 +46.42485366 +46.30113235 +46.22341985 +46.45441381 +67.49138338 +87.07110124 +77.23811372 +56.75245366 +63.09461102 +70.96419346 +77.6977627 +48.66623444 +45.23840377 +29.77694105 +89.99749477 +73.63939714 +66.79218328 +42.01402558 +0.034720565 +53.46430469 +36.70171467 +35.85962149 +35.76748941 +35.73067969 +37.26368216 +37.18359794 +33.5647448 +36.00319555 +52.71508226 +54.6764846 +33.62810874 +51.85861864 +35.38324225 +42.33320869 +53.23039422 +34.0287666 +33.57100969 +43.08628744 +42.4327981 +86.16851756 +66.49187572 +87.12465819 +51.51161746 +82.36381928 +70.35293566 +83.48302735 +86.75964424 +81.95441222 +86.20804066 +86.72556337 +88.04023817 +81.78360754 +80.83483152 +68.13744877 +72.35736999 +88.79588939 +84.03403753 +46.94634557 +84.22968779 +46.30285926 +85.75398947 +85.3509424 +86.19952432 +59.78059506 +60.12533588 +34.7547469 +53.42137701 +57.42734441 +52.26985682 +54.30897004 +55.37090275 +55.10529783 +55.54791939 +55.36441689 +56.45937131 +57.18943266 +56.32591116 +66.46821128 +76.53082676 +81.72566453 +46.34419862 +78.0050212 +24.24713339 +54.51959802 +42.70564187 +11.42039206 +51.55132936 +34.54900918 +80.31299062 +68.13627669 +66.55480876 +32.96799391 +51.84708886 +31.02589018 +47.31853265 +45.0741398 +0 +0 +0.009238109 +0 +36.37737748 +36.35492458 +37.04737 +37.78796145 +36.28643349 +35.56643564 +37.75582215 +35.25700321 +0.008016148 +37.68307631 +37.31842283 +36.05936178 +36.76222104 +35.62406124 +35.15032102 +36.84692109 +53.82616243 +43.42356675 +61.22690974 +37.50926408 +36.92202823 +0.004681019 +0.003617871 +43.26765346 +0.004488158 +0.004738058 +52.94643714 +37.80343691 +63.69031796 +70.29755406 +65.53798485 +52.81533993 +43.17935761 +54.50449033 +55.58438205 +36.52880887 +0.004963038 +46.4099374 +40.35602913 +46.42663606 +35.4830884 +53.17135031 +54.65259841 +53.59563774 +55.85803513 +54.40840577 +53.79918712 +50.65867095 +70.12744287 +52.00965133 +73.21716217 +52.96919585 +33.93777772 +43.13873085 +55.14510567 +85.54918272 +59.9434977 +57.38901861 +37.47094244 +53.83878373 +87.70367026 +89.98008953 +69.51482403 +55.48844486 +82.59065927 +66.81403949 +65.69618506 +54.22524009 +34.29913271 +49.1957454 +52.7587092 +46.20387389 +55.86306789 +56.60745372 +36.93550805 +63.04341032 +50.06477053 +57.03790012 +41.61607866 +41.95703113 +71.66417028 +74.91532933 +56.70690124 +53.12888805 +89.9928442 +54.90344821 +59.37022128 +50.50472719 +57.03172195 +52.92328814 +57.27289256 +35.45729351 +35.09758045 +44.2017558 +76.18681721 +30.61515556 +55.30722109 +56.41676113 +79.94739749 +56.83465796 +57.27531724 +56.49429287 +67.60522771 +72.83467922 +64.01215695 +74.12925096 +74.2437819 +62.49311381 +79.82901975 +79.58831186 +67.6570771 +66.71102643 +84.11375482 +81.85379358 +63.18383257 +48.57972331 +31.53960264 +27.79655395 +41.18929714 +41.31364835 +45.9745814 +46.61611145 +34.54556115 +45.22829595 +44.02133636 +46.80067814 +42.41809443 +59.04723947 +68.27411426 +62.02763728 +56.86989561 +77.98938813 +36.54306452 +0.018841336 +49.54552105 +36.60804018 +38.45799967 +0.338778227 +34.98870889 +39.43032877 +38.30471639 +35.78545244 +57.59598292 +47.85761198 +49.72405677 +49.38759254 +67.32583465 +37.22298602 +56.30694407 +23.22940683 +50.06147473 +49.81306609 +50.21372202 +37.4834313 +50.14806188 +50.28561151 +48.43624868 +50.54234276 +61.9236734 +52.71922275 +55.94960097 +60.81377172 +52.74548005 +76.27373781 +48.95092628 +55.55053547 +24.00498152 +35.05509423 +89.99987618 +51.83853591 +77.94817672 +89.99886602 +52.98021453 +34.05475407 +79.29197225 +20.70250975 +71.18648783 +62.17672001 +64.39999521 +40.30874114 +82.53191972 +0.849938071 +19.65782101 +35.08724998 +45.00164597 +53.59749303 +51.63303015 +17.9319227 +52.91523196 +45.60416843 +15.89598499 +46.35896913 +3.694446963 +41.08526187 +22.21538425 +3.97406129 +36.63186633 +44.36610939 +21.64850273 +34.74480253 +45.72188225 +66.58225705 +72.23489502 +60.44509902 +4.685916383 +21.85368774 +41.15003891 +89.97650969 +89.68473014 +9.560601133 +32.9842907 +37.25181639 +52.42207481 +54.06145578 +58.98622125 +58.10977854 +62.8202748 +53.32494315 +69.02696661 +75.21211437 +79.69952012 +46.90568939 +24.0673369 +37.47614582 +44.43254556 +55.05944045 +51.90030591 +12.64342066 +29.59140145 +37.83336916 +4.77664491 +38.66161328 +45.01860001 +39.36127379 +26.42637729 +33.22285419 +8.521405384 +37.0989451 +37.71445473 +35.14423069 +45.5855018 +43.69198997 +36.17574718 +51.50920057 +32.66541261 +34.38709961 +17.76087277 +88.21462681 +48.82674723 +49.6802389 +70.86080512 +73.67763965 +55.01157599 +71.40765279 +60.4190444 +71.09709486 +69.61009497 +72.40870127 +62.27839702 +61.37974263 +88.80886291 +72.35343439 +52.67906847 +67.42947896 +51.01187127 +89.99684003 +89.86552817 +60.64983321 +89.70289887 +36.82576792 +79.6930287 +55.07428287 +79.40404517 +88.86918034 +88.72232988 +35.4430048 +89.98452872 +36.93470405 +56.76786722 +85.30164884 +50.75647164 +35.56288995 +35.9114157 +71.0770351 +35.28777266 +58.37258816 +43.18003669 +56.69227924 +55.10009351 +49.90498519 +63.58094888 +82.79770752 +67.32216276 +49.57769056 +83.90005639 +14.57066183 +89.99579068 +36.63908631 +89.17677777 +78.20688697 +80.95411045 +89.54974656 +72.70313007 +82.41026514 +36.04123267 +73.91857878 +34.46381449 +35.62790987 +50.03502759 +47.41716814 \ No newline at end of file diff --git a/examples/tadf/TADF_angle/angle.py b/examples/tadf/TADF_angle/angle.py new file mode 100644 index 000000000..022f5604c --- /dev/null +++ b/examples/tadf/TADF_angle/angle.py @@ -0,0 +1,25 @@ +import hydra +from angle_model import eval +from angle_model import featurize_molecules +from angle_model import load_data +from angle_model import train +from omegaconf import DictConfig + + +@hydra.main(version_base=None, config_path="./config", config_name="angle.yaml") +def main(cfg: DictConfig): + + data, smis = load_data(cfg) + + X = featurize_molecules(smis) + + if cfg.mode == "train": + train(cfg, X, data) + elif cfg.mode == "eval": + eval(cfg, X, data) + else: + raise ValueError(f"cfg.mode should be 'train' or 'eval', but got '{cfg.mode}'") + + +if __name__ == "__main__": + main() diff --git a/examples/tadf/TADF_angle/angle_model.py b/examples/tadf/TADF_angle/angle_model.py new file mode 100644 index 000000000..d94853346 --- /dev/null +++ b/examples/tadf/TADF_angle/angle_model.py @@ -0,0 +1,190 @@ +import os + +import matplotlib.pyplot as plt +import numpy as np +import paddle +import rdkit.Chem as Chem +from omegaconf import DictConfig +from rdkit.Chem import rdFingerprintGenerator +from sklearn.decomposition import PCA +from sklearn.metrics import r2_score +from sklearn.model_selection import train_test_split + +import ppsci + +os.environ["HYDRA_FULL_ERROR"] = "1" +os.environ["KMP_DUPLICATE_LIB_OK"] = "True" +plt.rcParams["axes.unicode_minus"] = False +plt.rcParams["font.sans-serif"] = ["DejaVu Sans"] + +# 数据集准备 +def load_data(cfg): + data_dir = cfg.data_dir + sim_dir = cfg.sim_dir + angle_dat_path = os.path.join(data_dir) + smis_txt_path = os.path.join(sim_dir) + + data = [] + with open(angle_dat_path) as f: + for line in f: + num = float(line.strip()) / 90 + data.append(num) + + smis = [] + with open(smis_txt_path) as f: + for line in f: + smis.append(line.strip()) + + return data, smis + + +def featurize_molecules(smis): + vectors = [] + del_mol = [] + for s in smis: + mol = Chem.MolFromSmiles(s) + try: + generator = rdFingerprintGenerator.GetMorganGenerator(radius=2, fpSize=2048) + fp = generator.GetFingerprint(mol) + _input = np.array(list(map(int, fp.ToBitString()))) + vectors.append(_input) + except Exception as e: + print(f"Error processing {s}: {e}") + del_mol.append(s) + pca = PCA(n_components=0.99) + pca.fit(vectors) + X = pca.transform(vectors) + return paddle.to_tensor(X, dtype="float32") + + +def train(cfg: DictConfig, X, data): + # 划分数据集 + def k_fold(k, i, X, Y): + fold_size = X.shape[0] // k + val_start = i * fold_size + if i != k - 1: + val_end = (i + 1) * fold_size + x_val, y_val = X[val_start:val_end], Y[val_start:val_end] + x_train = paddle.concat((X[0:val_start], X[val_end:]), axis=0) + y_train = paddle.concat((Y[0:val_start], Y[val_end:]), axis=0) + else: + x_val, y_val = X[val_start:], Y[val_start:] + x_train = X[0:val_start] + y_train = Y[0:val_start] + return x_train, y_train, x_val, y_val + + Y = paddle.to_tensor(data, dtype="float32") + x_train, y_train, x_test, y_test = k_fold(cfg.TRAIN.k, cfg.TRAIN.i, X, Y) + # 处理数据集 + x = { + f"key_{i}": paddle.unsqueeze(x_train[:, i], axis=1) + for i in range(x_train.shape[1]) + } + + param = paddle.empty((len(x["key_0"]), len(x_train)), "float32") + param = ppsci.utils.initializer.xavier_normal_(param) + + # 构建约束 + bc_sup = ppsci.constraint.SupervisedConstraint( + dataloader_cfg={ + "dataset": { + "input": x, + "label": {"u": y_train}, + "weight": {"W": param}, + "name": "IterableNamedArrayDataset", + }, + "batch_size": cfg.TRAIN.batch_size, + }, + loss=ppsci.loss.MSELoss("mean"), + name="bc_sup", + ) + + # 设置模型 + hidden_size = [587, 256] + num_layers = None + # 实例化模型 + model = ppsci.arch.TADF( + input_keys=tuple(x.keys()), + hidden_size=hidden_size, + num_layers=num_layers, + **cfg.MODEL, + ) + optimizer = ppsci.optimizer.Adam( + learning_rate=cfg.TRAIN.learning_rate, + beta1=0.9, + beta2=0.99, + weight_decay=cfg.TRAIN.weight_decay, + )(model) + + # 构建Solver + solver = ppsci.solver.Solver( + model, + constraint={"bc_sup": bc_sup}, + optimizer=optimizer, + epochs=cfg.TRAIN.epochs, + iters_per_epoch=cfg.TRAIN.iters_per_epoch, + seed=cfg.seed, + ) + try: + solver.train() + except Exception as ex: + print(ex) + paddle.save(model.state_dict(), cfg.TRAIN.save_model_path) + + +# 进行测试 +def eval(cfg: DictConfig, X, data): + y = paddle.to_tensor(data, dtype="float32") + # 重新划分数据集 + x_train, x_test, y_train, y_test = train_test_split( + X.numpy(), y.numpy(), test_size=cfg.EVAL.test_size, random_state=cfg.EVAL.seed + ) + x_test = paddle.to_tensor(x_test, dtype="float32") + y_test = paddle.to_tensor(y_test, dtype="float32") + + x = { + f"key_{i}": paddle.unsqueeze(x_test[:, i], axis=1) + for i in range(x_test.shape[1]) + } + + hidden_size = [587, 256] + num_layers = None + model = ppsci.arch.TADF( + input_keys=tuple(x.keys()), + hidden_size=hidden_size, + num_layers=num_layers, + **cfg.MODEL, + ) + model.set_state_dict(paddle.load(cfg.EVAL.load_model_path)) + + ypred = model(x) + ytest = {"u": paddle.unsqueeze(y_test, axis=1)} + + # 计算损失 + mae_metric = ppsci.metric.MAE() + rmse_metric = ppsci.metric.RMSE() + MAE = mae_metric(ypred, ytest).get("u").numpy() + RMSE = rmse_metric(ypred, ytest).get("u").numpy() + R2 = r2_score(ytest["u"].numpy(), ypred.get("u").numpy()) + + print("MAE", MAE) + print("RMSE", RMSE) + print("R2", R2) + + # 可视化 + plt.scatter( + ytest["u"].numpy(), ypred.get("u").numpy(), s=15, color="royalblue", marker="s" + ) + plt.plot( + [ytest["u"].min(), ytest["u"].max()], + [ytest["u"].min(), ytest["u"].max()], + "r-", + lw=1, + ) + plt.legend(title=f"R²={R2:.3f}\n\nMAE={MAE:.3f}") + plt.xlabel("Test θ(°)") + plt.ylabel("Predicted θ(°)") + save_path = "test_angle.png" + plt.savefig(save_path) + print(f"图片已保存至：{save_path}") + plt.show() diff --git a/examples/tadf/TADF_angle/config/angle.yaml b/examples/tadf/TADF_angle/config/angle.yaml new file mode 100644 index 000000000..f472e403a --- /dev/null +++ b/examples/tadf/TADF_angle/config/angle.yaml @@ -0,0 +1,77 @@ +defaults: # + - ppsci_default # + - TRAIN: train_default # + - EVAL: eval_default # +# - INFER: infer_default # + - _self_ # + +hydra: + run: + # dynamic output directory according to running time and override name + dir: outputs_angle/${now:%Y-%m-%d}/${now:%H-%M-%S}/${hydra.job.override_dirname} # + job: + name: ${mode} # name of logfile + chdir: false # keep current working directory unchanged + callbacks: + init_callback: # + _target_: ppsci.utils.callbacks.InitCallback # + sweep: + # output directory for multirun + dir: ${hydra.run.dir} + subdir: ./ + +# general settings +mode: eval # running mode: train/eval # +seed: 42 # +output_dir: ${hydra:run.dir} # +log_freq: 20 # +use_tbd: false # +data_dir: "./angle.dat" +sim_dir: "./smis.txt" + +# model settings +MODEL: # + output_keys: ["u"] # + activation: "relu" # + dropout: 0.5 + +# training settings +TRAIN: # + epochs: 200 # + iters_per_epoch: 20 # + save_freq: 100 # + eval_during_train: False # + batch_size: 8 # + learning_rate: 0.01 + save_model_path: './angle_model.pdparams' + weight_decay: 1e-5 + pretrained_model_path: null # + checkpoint_path: null # + k: 9 + i: 2 + +# evaluation settings +EVAL: + test_size: 0.1 + load_model_path: './angle_pretrained.pdparams' + seed: 20 + pretrained_model_path: null + +# inference settings +#INFER: # +# pretrained_model_path: "https://github.com/YfB1125/PaddleScience/blob/dev_model/TADF/f/output/checkpoints/latest.pdparams" # +# export_path: ./inference/viv # +# pdmodel_path: ${INFER.export_path}.pdmodel # +# pdiparams_path: ${INFER.export_path}.pdiparams # +# input_keys: ${MODEL.input_keys} # +# output_keys: ["u"] # +# device: cpu # +# engine: native # +# precision: fp32 # +# ir_optim: true # +# min_subgraph_size: 10 # +# gpu_mem: 4000 # +# gpu_id: 0 # +# max_batch_size: 64 # +# num_cpu_threads: 4 # +# batch_size: 16 # diff --git a/examples/tadf/TADF_angle/smis.txt b/examples/tadf/TADF_angle/smis.txt new file mode 100644 index 000000000..06fd4771c --- /dev/null +++ b/examples/tadf/TADF_angle/smis.txt @@ -0,0 +1,5136 @@ +c1cc(-c2c3ccoc3cc3ccoc23)n[nH]1 +c1cc(-c2c3cc[nH]c3cc3occc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c3cc[nH]c3cc3occc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2c3cc[nH]c3cc3occc23)c2[nH]nnc2c1 +c1cc(-c2c3ncoc3cc3ncoc23)c2c(c1)cnc1ccccc12 +c1cc(-c2c3ncoc3nc3ocnc23)c2nn[nH]c2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2scnc2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2[nH]c3ccncc3c2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2[nH]ccc2c1 +c1cc(-c2c3ncoc3nc3ocnc23)cnn1 +c1cc(-c2c3ncsc3cc3ncsc23)c2ncoc2c1 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2c(c1)sc1ncccc12 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2ccoc2c1 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2c(c1)cnc1ccccc12 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2ocnc2c1 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2[nH]nnc2c1 +c1cc(-c2c3[nH]cnc3cc3nc[nH]c23)c2[nH]nnc2c1 +c1cc(-c2c3[nH]cnc3cc3nc[nH]c23)[nH]n1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cc3cccnc3c3ncccc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cc3[nH]ccc3cn2)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccc3c(c2)[nH]c2cnccc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cccc3cnc4ccccc4c23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cccc3ocnc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccnc3c2ccc2cccnc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cncc3[nH]c4ccccc4c23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2coc3cc4ccoc4cc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2nc3cc4ncoc4nc3o2)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-n2cnc3cc4nc[nH]c4cc32)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)ccc1-c1cnoc1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2nccnc2c1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2sccc2c1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2[nH]c3cnccc3c2c1 +c1cc(-c2cc3cc4cc[nH]c4cc3o2)c2ocnc2c1 +c1cc(-c2cc3cc4cc[nH]c4cc3o2)c2[nH]nnc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2ncsc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2occc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2ocnc2c1 +c1cc(-c2cc3cnccc3[nH]2)c2nn[nH]c2c1 +c1cc(-c2cc3cnccc3[nH]2)c2occc2c1 +c1cc(-c2cc3cnccc3[nH]2)c2[nH]c3ccncc3c2c1 +c1cc(-c2cc3cnccc3[nH]2)c2[nH]nnc2c1 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2[nH]c3ccncc3c2c1 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2[nH]ccc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2ccoc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2ccsc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2cc[nH]c2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)n[nH]1 +c1cc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c2nccnc2c1 +c1cc(-c2cc3[nH]c4ccccc4c3cn2)c2nccnc2c1 +c1cc(-c2cc3[nH]c4ccccc4c3cn2)c2sccc2c1 +c1cc(-c2cc3[nH]c4ccncc4c3cn2)c2ccoc2c1 +c1cc(-c2cc3[nH]ccc3cn2)c2c(c1)sc1ncccc12 +c1cc(-c2cc3[nH]ccc3cn2)c2ncoc2c1 +c1cc(-c2cc3[nH]ccc3cn2)c2nn[nH]c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2cc[nH]c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2ncsc2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2[nH]nnc2c1 +c1(c2nccnc2)cccc(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +c1cc(-c2ccc3c(c2)c2ccccc2c2nccnc32)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2[nH]nnc2c1 +c1cc(-c2ccc3c(c2)ncc2ccccc23)c2occc2c1 +c1cc(-c2ccc3c(c2)oc2ccccc23)c2nn[nH]c2c1 +c1cc(-c2ccc3c(c2)oc2ncccc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c(c2)sc2ccccc23)c2ccoc2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2nn[nH]c2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2[nH]nnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)cc(-c2cnccn2)c1 +c1cc(-c2ccc3c(c2)[nH]c2ccncc23)c2ocnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ccsc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2cc[nH]c2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ncoc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ocnc2c1 +c1cc(-c2ccc3c(cnc4ccccc43)c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(cnc4ccccc43)c2)c2occc2c1 +c1cc(-c2ccc3c(n2)sc2ncccc23)c2nccnc2c1 +c1cc(-c2ccc3c(n2)sc2ncccc23)c2[nH]nnc2c1 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2cc[nH]c2c1 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2sccc2c1 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2nccnc2c1 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2[nH]nnc2c1 +c1cc(-c2ccc3c4ccccc4c4nccnc4c3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c4ccccc4c4nccnc4c3c2)c2ccsc2c1 +c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)c2sccc2c1 +c1cc(-c2ccc3ccc4cccnc4c3n2)c2[nH]ccc2c1 +c1cc(-c2ccc3ccoc3c2)no1 +c1cc(-c2ccc3ccsc3c2)c2ccoc2c1 +c1cc(-c2ccc3cc[nH]c3c2)c2ncoc2c1 +c1cc(-c2ccc3cc[nH]c3c2)c2nn[nH]c2c1 +c1cc(-c2ccc3cnc4ccccc4c3c2)c2scnc2c1 +c1cc(-c2ccc3cnc4ccccc4c3c2)c2[nH]ccc2c1 +c1cc(-c2ccc3ncc4ccccc4c3c2)c2occc2c1 +c1cc(-c2ccc3ncccc3n2)c2[nH]ccc2c1 +c1cc(-c2ccc3nccnc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3nccnc3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3ncoc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3ncoc3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3ncoc3c2)c2ccoc2c1 +c1cc(-c2ccc3ncoc3c2)c2cc[nH]c2c1 +c1cc(-c2ccc3ncsc3c2)c2sccc2c1 +c1cc(-c2ccc3nn[nH]c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3nn[nH]c3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3oc4ccccc4c3c2)c2nn[nH]c2c1 +c1cc(-c2ccc3oc4ncccc4c3c2)c2ncoc2c1 +c1cc(-c2ccc3oc4ncccc4c3c2)c2ocnc2c1 +c1cc(-c2ccc3occc3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3ocnc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3ocnc3c2)c2ncsc2c1 +c1cc(-c2ccc3ocnc3c2)c2occc2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3sc4ccccc4c3c2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3sc4ccccc4c3c2)c2cc[nH]c2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2ncoc2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2[nH]nnc2c1 +c1cc(-c2ccc3sccc3c2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3sccc3c2)c2ncoc2c1 +c1cc(-c2ccc3sccc3c2)c2sccc2c1 +c1cc(-c2ccc3sccc3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3sccc3c2)c2[nH]ccc2c1 +c1cc(-c2ccc3sccc3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3scnc3c2)c2ocnc2c1 +c1cc(-c2ccc3scnc3c2)no1 +c1cc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3[nH]c4ccncc4c3c2)c2[nH]nnc2c1 +c1cc(-c2ccc3[nH]c4cnccc4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ccoc2c1 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ncsc2c1 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ocnc2c1 +c1cc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]nnc3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3[nH]nnc3c2)c2ncoc2c1 +c1cc(-c2ccc3[nH]nnc3c2)c2scnc2c1 +c1cc(-c2cccc3c2cnc2ccccc23)c2ocnc2c1 +c1cc(-c2cccc3c2oc2ccccc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3c2oc2ccccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3c2sc2ncccc23)c2nn[nH]c2c1 +c1cc(-c2cccc3c2sc2ncccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c2nccnc2c1 +c1cc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c2ocnc2c1 +c1cc(-c2cccc3c2[nH]c2ccncc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3c2[nH]c2ccncc23)c2ocnc2c1 +c1cc(-c2cccc3c2[nH]c2cnccc23)c2scnc2c1 +c1cc(-c2cccc3c2[nH]c2cnccc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)c2nccnc2c1 +c1cc(-c2cccc3c4ccccc4c4nccnc4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c2nccnc2c1 +c1cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c2ncoc2c1 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2ccsc2c1 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2nn[nH]c2c1 +c1cc(-c2cccc3ccsc23)c2[nH]ccc2c1 +c1cc(-c2cccc3ncoc23)c2nccnc2c1 +c1cc(-c2cccc3ncsc23)c2nccnc2c1 +c1cc(-c2cccc3nn[nH]c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2sccc2c1 +c1cc(-c2cccc3oc4ncccc4c23)c2nccnc2c1 +c1cc(-c2cccc3oc4ncccc4c23)c2sccc2c1 +c1cc(-c2cccc3ocnc23)c2ccoc2c1 +c1cc(-c2cccc3ocnc23)c2occc2c1 +c1cc(-c2cccc3sc4ncccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3sc4ncccc4c23)c2ocnc2c1 +c1cc(-c2cccc3sccc23)c2ccsc2c1 +c1cc(-c2cccc3scnc23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3scnc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3[nH]c4cnccc4c23)c2occc2c1 +c1cc(-c2cccc3[nH]c4ncccc4c23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c2nccnc2c1 +c1cc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c2nn[nH]c2c1 +c1cc(-c2cccc3[nH]ccc23)c2ocnc2c1 +c1cc(-c2cccc3[nH]ccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3[nH]nnc23)c2occc2c1 +c1cc(-c2ccnc3c2ccc2cccnc23)c2[nH]ccc2c1 +c1cc(-c2ccnc3cccnc23)c2[nH]ccc2c1 +c1cc(-c2ccnc3ncccc23)c2scnc2c1 +c1cc(-c2ccnc3oc4ccccc4c23)c2sccc2c1 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2ncoc2c1 +c1cc(-c2ccnc3[nH]c4ccccc4c23)c2[nH]ccc2c1 +c1cc(-c2ccnnc2)c2sccc2c1 +c1cc(-c2ccno2)c2c(c1)oc1ncccc12 +c1cc(-c2ccno2)c2c(c1)sc1ncccc12 +c1cc(-c2ccno2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ccno2)[nH]n1 +c1cc(-c2ccn[nH]2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccon2)c2ccoc2c1 +c1cc(-c2ccon2)c2nn[nH]c2c1 +c1cc(-c2ccon2)n[nH]1 +c1cc(-c2cc[nH]n2)c2ccsc2c1 +c1cc(-c2cc[nH]n2)c2ncoc2c1 +c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c2ocnc2c1 +c1cc(-c2cnc3ccccc3n2)c2c(c1)cnc1ccccc12 +c1cc(-c2cnc3nccnc3n2)c2ccoc2c1 +c1cc(-c2cnc3nccnc3n2)c2ncoc2c1 +c1cc(-c2cnc3nccnc3n2)c2[nH]c3cnccc3c2c1 +c1cc(-c2cnc3oc4ccccc4c3c2)c2sccc2c1 +c1cc(-c2cnc3oc4ccccc4c3c2)c2[nH]nnc2c1 +c1cc(-c2cnc3sc4ccccc4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2cnc3sc4ncccc4c3c2)c2nn[nH]c2c1 +c1cc(-c2cnc3sc4ncccc4c3c2)cc(-c2cnccn2)c1 +c1cc(-c2cncc3c2[nH]c2ccncc23)c2c(c1)sc1ncccc12 +c1cc(-c2cncc3cc[nH]c23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cncc3cc[nH]c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cncc3cc[nH]c23)c2ncsc2c1 +c1cc(-c2cncc3cc[nH]c23)c2[nH]c3ccncc3c2c1 +c1cc(-c2cncc3cc[nH]c23)c2[nH]nnc2c1 +c1cc(-c2cncc3[nH]c4ccccc4c23)c2[nH]ccc2c1 +c1cc(-c2cnccn2)cc(-c2cc3ccccc3s2)c1 +c1cc(-c2cnccn2)cc(-c2cc3ccccc3[nH]2)c1 +c1cc(-c2cnccn2)cc(-c2cc3nc4ccoc4nc3[nH]2)c1 +c1cc(-c2cnccn2)cc(-c2cccc3ncc4ccccc4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3oc4ncccc4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3sccc23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3[nH]ccc23)c1 +c1cc(-c2cnccn2)cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +c1cc(-c2cnccn2)cc(-c2coc3cc4ccoc4cc23)c1 +c1cc(-c2cnccn2)cc(-c2c[nH]c3nc4occc4nc23)c1 +c1cc(-c2cnccn2)cc(-c2nccc3[nH]c4ccncc4c23)c1 +c1cc(-c2cnccn2)cc(-n2c3ccccc3c3c4ccccc4[nH]c32)c1 +c1cc(-c2cnccn2)cc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c1 +c1cc(-c2cnccn2)cc(-n2ccc3cc4ccoc4cc32)c1 +c1cc(-c2cnccn2)cc(-n2cnc3c4ccccc4c4ccccc4c32)c1 +c1cc(-c2cncs2)c2[nH]ccc2c1 +c1cc(-c2cnoc2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cnoc2)c2ccoc2c1 +c1cc(-c2cnoc2)[nH]n1 +c1cc(-c2cn[nH]c2)c2c(c1)cnc1ccccc12 +c1cc(-c2cn[nH]c2)c2[nH]nnc2c1 +c1cc(-c2cn[nH]c2)on1 +c1cc(-c2coc3cc4ccoc4cc23)c2c(c1)cnc1ccccc12 +c1cc(-c2coc3cc4ccoc4cc23)no1 +c1cc(-c2coc3cc4[nH]ccc4cc23)c2ocnc2c1 +c1cc(-c2coc3cc4[nH]ccc4cc23)c2[nH]nnc2c1 +c1cc(-c2coc3ccccc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2coc3ccccc23)c2sccc2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2cc[nH]c2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2ncsc2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2scnc2c1 +c1cc(-c2csc3ccccc23)c2ncoc2c1 +c1cc(-c2c[nH]c3cc4occc4cc23)c2ocnc2c1 +c1cc(-c2c[nH]c3cc4occc4cc23)no1 +c1cc(-c2c[nH]c3ccccc23)c2sccc2c1 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)oc1ncccc12 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c[nH]c3ccncc23)c2ocnc2c1 +c1cc(-c2c[nH]c3ccncc23)c2[nH]c3ccncc3c2c1 +c1cc(-c2c[nH]c3nc4occc4nc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c[nH]c3nc4occc4nc23)n[nH]1 +c1cc(-c2c[nH]c3nc4occc4nc23)[nH]n1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2nc3cc4ncoc4nc3o2)c2cc[nH]c2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2ncsc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2occc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2[nH]c3cnccc3c2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2[nH]ccc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)n[nH]1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)c2occc2c1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)c2sccc2c1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)cnn1 +c1cc(-c2nc3cc4ocnc4cc3o2)c2c(c1)cnc1ccccc12 +c1cc(-c2nc3cc4ocnc4cc3o2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2nc3cc4ocnc4cc3o2)c2ccsc2c1 +c1cc(-c2nc3cc4ocnc4cc3o2)c2[nH]nnc2c1 +c1cc(-c2nc3cc4scnc4cc3s2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2nc3cc4scnc4cc3s2)c2ccsc2c1 +c1cc(-c2nc3cc4scnc4cc3s2)c2nccnc2c1 +c1cc(-c2nc3ccccc3c3ccccc23)c2ocnc2c1 +c1cc(-c2nc3ccccc3o2)c2occc2c1 +c1cc(-c2nc3nc4nc[nH]c4cc3[nH]2)c2c(c1)oc1ncccc12 +c1cc(-c2nc3nc4nc[nH]c4cc3[nH]2)c2cc[nH]c2c1 +c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2c(c1)sc1ncccc12 +c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2[nH]c3cnccc3c2c1 +c1cc(-c2nc3nc4ocnc4nc3o2)c2c(c1)sc1ncccc12 +c1cc(-c2nc3nc4ocnc4nc3o2)c2scnc2c1 +c1cc(-c2nccc3c2[nH]c2ccccc23)c2cc[nH]c2c1 +c1cc(-c2nccc3[nH]c4ccccc4c23)c2[nH]nnc2c1 +c1cc(-c2nccc3[nH]c4ccncc4c23)c2[nH]c3ccncc3c2c1 +c1cc(-c2nccc3[nH]ccc23)c2c(c1)cnc1ccccc12 +c1cc(-c2nccc3[nH]ccc23)c2c(c1)sc1ncccc12 +c1cc(-c2nccc3[nH]ccc23)c2nn[nH]c2c1 +c1cc(-c2nccs2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2nccs2)c2ncsc2c1 +c1cc(-c2nccs2)c2[nH]nnc2c1 +c1cc(-c2ncno2)c2ccoc2c1 +c1cc(-c2ncon2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ncon2)c2sccc2c1 +c1cc(-c2ncon2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ncon2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ncon2)c2[nH]nnc2c1 +c1cc(-c2ncon2)[nH]n1 +c1cc(-n2c3ccccc3c3c4ccccc4[nH]c32)c2[nH]nnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2nccnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2ocnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2sccc2c1 +c1cc(-n2c3ccccc3c3cccnc32)c2c(c1)cnc1ccccc12 +c1cc(-n2c3ccccc3c3cccnc32)c2ncsc2c1 +c1cc(-n2c3ccccc3c3cccnc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2occc2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2[nH]nnc2c1 +c1cc(-n2c3ccccc3c3cnccc32)c2ocnc2c1 +c1cc(-n2c3ccncc3c3cnccc32)c2nn[nH]c2c1 +c1cc(-n2c3ccncc3c3cnccc32)c2ocnc2c1 +c1cc(-n2ccc3cc4ccoc4cc32)c2c(c1)cnc1ccccc12 +c1cc(-n2ccc3cc4ccoc4cc32)c2[nH]c3cnccc3c2c1 +c1cc(-n2ccc3cnccc32)c2c(c1)oc1ncccc12 +c1cc(-n2ccc3cnccc32)c2c(c1)[nH]c1ccncc12 +c1cc(-n2ccc3nc4ccoc4nc32)c2ncoc2c1 +c1cc(-n2cccn2)c2ncoc2c1 +c1cc(-n2cccn2)c2[nH]c3cnccc3c2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)c2ncsc2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)[nH]n1 +c1cc(-n2cnc3nc4nc[nH]c4nc32)c2ncoc2c1 +c1cc(-n2cnc3nc4nc[nH]c4nc32)c2[nH]ccc2c1 +c1cc2c(-c3c4ncoc4nc4ocnc34)c3ccoc3cc2[nH]1 +c1cc2c(-c3ccc4ncoc4c3)c3ccoc3cc2[nH]1 +c1cc2c(-c3ccc4[nH]nnc4c3)c3ccoc3cc2[nH]1 +c1cc2c(-n3cnc4nc5nc[nH]c5nc43)c3ccoc3cc2[nH]1 +c1cc2c(ccn2-c2cc3nc4ccoc4nc3[nH]2)cn1 +c1cc2c(ccn2-c2ccc3c(c2)[nH]c2ccncc23)cn1 +c1cc2c(ccn2-c2c[nH]c3nc4occc4nc23)cn1 +c1cc2c(ccn2-c2nc3cc4ocnc4cc3o2)cn1 +c1cc2c(ccn2-n2c3ccncc3c3cnccc32)cn1 +c1cc2c(ccn2-n2ccc3nc4ccoc4nc32)cn1 +c1cc2c(cn1)c1cnccc1n2-c1c2ccoc2cc2ccoc12 +c1cc2c(cn1)c1cnccc1n2-c1c2ncoc2cc2ncoc12 +c1cc2c(cn1)c1cnccc1n2-c1c2ncoc2nc2ocnc12 +c1cc2c(cn1)c1cnccc1n2-c1c2[nH]cnc2cc2nc[nH]c12 +c1cc2c(cn1)c1cnccc1n2-c1cc2cc3occc3cc2o1 +c1cc2c(cn1)c1cnccc1n2-c1cc2[nH]ccc2cn1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2c3c1CCCN3CCC2 +c1cc2c(cn1)c1cnccc1n2-c1ccc2cc[nH]c2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2ncoc2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2ocnc2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2scnc2c1 +c1cc2c(cn1)c1cnccc1n2-c1c[nH]c2cc3occc3cc12 +c1cc2c(cn1)c1cnccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1cc2c(cn1)[nH]c1cc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4ncoc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4nn[nH]c4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4ocnc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4scnc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1cc2c(cn1)[nH]c1cc(-n3cnc4cc5nc[nH]c5cc43)ccc12 +c1cc2c(cn1)[nH]c1cc(-n3cnc4nc5nc[nH]c5cc43)ccc12 +c1cc2c(cn1)[nH]c1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3ccc4cc[nH]c4c3)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3ccc4[nH]ccc4c3)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3cncc4c3[nH]c3ccncc34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3coc4cc5[nH]ccc5cc34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3nc4cc5ocnc5cc4o3)cc12 +c1cc2cc(-c3ccc4nn[nH]c4c3)ccc2s1 +c1cc2cc(-c3ccc4ocnc4c3)ccc2o1 +c1cc2cc(-n3ccc4nc5ccoc5nc43)ccc2o1 +c1cc2cc3c(-c4c5ncoc5nc5ocnc45)coc3cc2[nH]1 +c1cc2cc3c(-c4ccc5ccsc5c4)c[nH]c3cc2o1 +c1cc2cc3c(-c4ccc5nn[nH]c5c4)c[nH]c3cc2o1 +c1cc2cc3c(-c4ccon4)coc3cc2[nH]1 +c1cc2cc3c(-c4cnoc4)c[nH]c3cc2o1 +c1cc2cc3c(-c4nc5nc6nc[nH]c6nc5[nH]4)coc3cc2[nH]1 +c1cc2cc3c(-c4ncon4)coc3cc2[nH]1 +c1cc2cc3c(-n4cnc5cc6nc[nH]c6cc54)coc3cc2[nH]1 +c1cc2cc3c(-n4cnc5nc6nc[nH]c6cc54)coc3cc2[nH]1 +c1cc2cc3cc(-c4cc5cc6occc6cc5o4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5ccsc5c4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5sccc5c4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5[nH]nnc5c4)[nH]c3cc2o1 +c1cc2cc3cc(-c4coc5cc6ccoc6cc45)[nH]c3cc2o1 +c1cc2cc3cc(-c4nc5cc6ncoc6nc5o4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ncon4)oc3cc2[nH]1 +c1cc2cc3cc(-n4ccc5nc6ccoc6nc54)oc3cc2[nH]1 +c1cc2cc3ccn(-c4ccc5ccsc5c4)c3cc2o1 +c1cc2cc3ccn(-c4ccc5nn[nH]c5c4)c3cc2o1 +c1cc2cc3ccoc3c(-c3c4ncoc4nc4ocnc34)c2[nH]1 +c1cc2cc3ccoc3c(-c3cc4cc5occc5cc4o3)c2[nH]1 +c1cc2cc3ccoc3c(-c3ccc4ccsc4c3)c2[nH]1 +c1cc2cc3occ(-c4cn[nH]c4)c3cc2o1 +c1cc2cc3occ(-n4ccc5nc6ccoc6nc54)c3cc2o1 +c1cc2ccc(-c3ccc4[nH]nnc4c3)cc2[nH]1 +c1cc2ccc(-c3cncs3)cc2[nH]1 +c1cc2ccc(-c3cn[nH]c3)cc2s1 +c1cc2ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc2[nH]1 +c1cc2ccc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc2[nH]1 +c1cc2cnc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)cc2[nH]1 +c1cc2cnc(-c3ccc4scnc4c3)cc2[nH]1 +c1cc2cnc(-c3coc4cc5[nH]ccc5cc34)cc2[nH]1 +c1cc2cnc(-c3c[nH]c4cc5occc5cc34)cc2[nH]1 +c1cc2cnc(-n3ccc4nc5ccoc5nc43)cc2[nH]1 +c1cc2cncc(-c3c4[nH]ccc4cc4ccoc34)c2[nH]1 +c1cc2cncc(-c3ccc4ccsc4c3)c2[nH]1 +c1cc2cncc(-c3ccc4ncoc4c3)c2[nH]1 +c1cc2cncc(-c3ccc4[nH]nnc4c3)c2[nH]1 +c1cc2nc3c(-c4c5ncoc5nc5ocnc45)coc3nc2[nH]1 +c1cc2nc3c(-c4c5ncsc5cc5ncsc45)c[nH]c3nc2o1 +c1cc2nc3c(-c4ccc5nn[nH]c5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4ccc5sccc5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4ccc5[nH]nnc5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4coc5cc6ccoc6cc45)coc3nc2[nH]1 +c1cc2nc3c(-c4nc5nc6ocnc6nc5o4)c[nH]c3nc2o1 +c1cc2nc3cc(-c4c5ncoc5nc5ocnc45)oc3nc2[nH]1 +c1cc2nc3cc(-c4c5ncoc5nc5ocnc45)[nH]c3nc2o1 +c1cc2nc3cc(-c4ccc5ocnc5c4)oc3nc2[nH]1 +c1cc2nc3cc(-c4ccon4)oc3nc2[nH]1 +c1cc2nc3cc(-c4cn[nH]c4)oc3nc2[nH]1 +c1cc2nc3ccn(-c4c5ncsc5cc5ncsc45)c3nc2o1 +c1cc2nc3ccn(-c4ccc5sccc5c4)c3nc2o1 +c1cc2nc3ccn(-c4ccc5scnc5c4)c3nc2o1 +c1cc2nc3ccn(-c4ccc5[nH]nnc5c4)c3nc2o1 +c1cc2nc3ccn(-c4cscn4)c3nc2o1 +c1cc2[nH]c(-c3ccc4sccc4c3)cc2cn1 +c1cc2[nH]c(-c3coc4cc5ccoc5cc34)cc2cn1 +c1cc2[nH]c3c(-c4c5ccoc5cc5ccoc45)cncc3c2cn1 +c1cc2[nH]c3c(-c4c5ncsc5cc5ncsc45)cncc3c2cn1 +c1cc2[nH]c3c(-c4c5[nH]cnc5cc5nc[nH]c45)cncc3c2cn1 +c1cc2[nH]c3c(-c4cc5cc6ccoc6cc5[nH]4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccc5sccc5c4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccc5scnc5c4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccno4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccon4)cncc3c2cn1 +c1cc2[nH]c3c(-c4cnoc4)cncc3c2cn1 +c1cc2[nH]c3c(-c4c[nH]c5nc6occc6nc45)cncc3c2cn1 +c1cc2[nH]c3cc(-c4c5cc[nH]c5cc5occc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cc5c6c(c4)CCCN6CCC5)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cc5cc6ccoc6cc5[nH]4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5ccoc5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5[nH]c6ccncc6c5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5[nH]nnc5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cncc5c4[nH]c4ccncc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4coc5nc6[nH]ccc6nc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4nc5cc6nc[nH]c6cc5[nH]4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4nc5nc6nc[nH]c6cc5[nH]4)ccc3c2cn1 +c1cc2[nH]c3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c2cn1 +c1cc2[nH]c3ccc(-c4cc5nc6cc[nH]c6nc5o4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4cc5[nH]ccc5cn4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4nc5nc6nc[nH]c6nc5[nH]4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4ncon4)cc3c2cn1 +c1cc2[nH]c3ccnc(-c4c5ccoc5cc5ccoc45)c3c2cn1 +c1cc2[nH]c3ccnc(-c4cc5c6c(c4)CCCN6CCC5)c3c2cn1 +c1cc2[nH]c3ccnc(-c4ccc5nn[nH]c5c4)c3c2cn1 +c1cc2[nH]c3ccnc(-c4cnoc4)c3c2cn1 +c1cc2[nH]c3ccnc(-c4ncno4)c3c2cn1 +c1cc2[nH]cc(-c3ccc4[nH]nnc4c3)c2cn1 +c1cc2[nH]cc(-c3ccn[nH]3)c2cn1 +c1cc2[nH]cc(-c3cncc4c3[nH]c3ccncc34)c2cn1 +c1cc2[nH]cc(-c3coc4cc5[nH]ccc5cc34)c2cn1 +c1cc2[nH]cc(-c3coc4nc5[nH]ccc5nc34)c2cn1 +c1cc2[nH]cc(-c3nc4cc5ocnc5cc4o3)c2cn1 +c1cc2[nH]cc(-n3cnc4nc5nc[nH]c5nc43)c2cn1 +c1cc2[nH]ccc2c(-c2cc3cc4ccoc4cc3[nH]2)n1 +c1cc2[nH]ccc2c(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cc2)n1 +c1cc2[nH]ccc2c(-c2ccc3ccoc3c2)n1 +c1ccc(-c2c3[nH]ccc3cc3ccoc23)c(-c2cnccn2)c1 +c1ccc(-c2c3[nH]cnc3cc3nc[nH]c23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1(c2nccc(c2)c2ccc3CCc4c(cccc4)Nc3c2)ncccc1 +c1ccc(-c2cc(-c3ccc4c(n3)sc3ncccc34)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4c5c3CCCN5CCC4)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4oc5ccccc5c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c3sc3ncccc34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c3[nH]c3cnccc34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c5ccccc5c5nccnc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4cnc5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3cncc4[nH]c5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3coc4cc5ccoc5cc34)ccn2)nc1 +c1ccc(-c2cc(-c3coc4nc5[nH]ccc5nc34)ccn2)nc1 +c1ccc(-c2cc(-c3nccc4[nH]c5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc3c4c(c2-c2cc5cccnc5c5ncccc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cc5cnccc5[nH]2)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5c2[nH]c2ncccc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5cnc6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5ocnc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5sc6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cncc5[nH]c6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)c(-c2cnccn2)c1 +c1ccc(-c2cc3nc4cc[nH]c4nc3o2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cc3nc4cc[nH]c4nc3o2)c(-c2cnccn2)c1 +c1(c2ncc(cc2)N2c3c(Sc4c2cccc4)cccc3)ncccc1 +c1ccc(-c2ccc(-c3c4cc[nH]c4cc4occc34)cn2)nc1 +c1ccc(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cn2)nc1 +c1(c2ncc(cc2)c2cc3c(Sc4c(cccc4)N3)cc2)ncccc1 +c1ccc(-c2ccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)cn2)nc1 +c1ccc(-c2ccc(-c3ccc4c(c3)Oc3ccccc3O4)cn2)nc1 +c1ccc(-c2ccc(-c3ccc4c(c3)[nH]c3ccncc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c3cnc3ccccc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c3[nH]c3cnccc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4cc[nH]c34)cn2)nc1 +c1ccc(-c2ccc(-c3ccnnc3)cn2)nc1 +c1ccc(-c2ccc(-c3cnc4oc5ccccc5c4c3)cn2)nc1 +c1ccc(-c2ccc(-c3cnc4sc5ncccc5c4c3)cn2)nc1 +c1ccc(-c2ccc(-n3c4ccccc4c4c5ccccc5[nH]c43)cn2)nc1 +c1ccc(-c2ccc(-n3c4ccccc4c4cnccc43)cn2)nc1 +c1ccc(-c2ccc3c(c2)[nH]c2cnccc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccc3ccc4cccnc4c3n2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccc3nn[nH]c3c2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc(-c3c4ccoc4cc4ccoc34)n2)nc1 +c1ccc(-c2cccc(-c3c4cc[nH]c4cc4occc34)n2)nc1 +c1ccc(-c2cccc(-c3cc4cc5occc5cc4o3)n2)nc1 +c1ccc(-c2cccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)n2)nc1 +c1(c2ncccc2)nc(ccc1)c1cc2CCc3c(cccc3)Nc2cc1 +c1ccc(-c2cccc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)n2)nc1 +c1ccc(-c2cccc(-c3ccc4cc[nH]c4c3)n2)nc1 +c1ccc(-c2cccc(-c3ccc4ncoc4c3)n2)nc1 +c1ccc(-c2cccc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)n2)nc1 +c1ccc(-c2cccc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)nc1 +c1(c2ncccc2)nc(ccc1)c1c2CCc3c(cccc3)Nc2ccc1 +c1ccc(-c2cccc(-c3cccc4c3oc3ccccc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4oc5ccccc5c34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4ocnc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4sccc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)n2)nc1 +c1ccc(-c2cccc(-c3cccnn3)n2)nc1 +c1ccc(-c2cccc(-c3cnc4oc5ccccc5c4c3)n2)nc1 +c1ccc(-c2cccc(-c3cnc4sc5ccccc5c4c3)n2)nc1 +c1ccc(-c2cccc(-c3coc4cc5ccoc5cc34)n2)nc1 +c1ccc(-c2cccc(-c3coc4nc5[nH]ccc5nc34)n2)nc1 +c1ccc(-c2cccc(-n3c4ccccc4c4c5ccccc5[nH]c43)n2)nc1 +c1ccc(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c2[nH]c2ccncc23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c2[nH]c2ncccc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc3c4ccccc4c4nccnc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3cc[nH]c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3ocnc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc3sc4ncccc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]c4ccncc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]nnc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccn[nH]2)c(-c2cnccn2)c1 +c1ccc(-c2cnc(-c3c4ccoc4cc4ccoc34)cn2)cc1 +c1ccc(-c2cnc(-c3c4ncoc4cc4ncoc34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)Oc3ccccc3O4)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)[nH]c3ccncc34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4cnc5ccccc5c4c3)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4ncsc4c3)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c3cnc3ccccc34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4ncsc34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4oc5ncccc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccnn3)cn2)cc1 +c1ccc(-c2cnc(-c3coc4ccccc34)cn2)cc1 +c1ccc(-c2cnc(-c3c[nH]c4nc5occc5nc34)cn2)cc1 +c1ccc(-c2cnc(-n3ccc4ccccc43)cn2)cc1 +c1ccc(-c2cnc3[nH]c4ccccc4c3c2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cncc(-c3cc4cc5ccoc5cc4[nH]3)n2)cc1 +c1ccc(-c2cncc(-c3cc4cc5occc5cc4o3)n2)cc1 +c1ccc(-c2cncc(-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +c1ccc(-c2cncc(-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)ncc3ccccc34)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)oc3ccccc34)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(cnc5ccccc54)c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4ccsc4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4ncc5ccccc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4sccc4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4[nH]c5ccncc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +c1(c2nc(cnc2)c2c3c(CCc4c(cccc4)N3)ccc2)ccccc1 +c1ccc(-c2cncc(-c3cccc4c3[nH]c3ccncc34)n2)cc1 +c1ccc(-c2cncc(-c3cccc4c5ccccc5c5nccnc5c34)n2)cc1 +c1ccc(-c2cncc(-c3cccc4cnc5ccccc5c34)n2)cc1 +c1ccc(-c2cncc(-c3cnc4sc5ncccc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3cncc4c3[nH]c3ccccc34)n2)cc1 +c1ccc(-c2cncc(-n3c4ccccc4c4c5ccccc5[nH]c43)n2)cc1 +c1ccc(-c2cnccn2)c(-c2ccc3c(c2)c2ccccc2c2nccnc32)c1 +c1ccc(-c2cnccn2)c(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +c1ccc(-c2cnccn2)c(-c2ccc3ccoc3c2)c1 +c1ccc(-c2cnccn2)c(-c2ccc3sccc3c2)c1 +c1ccc(-c2cncs2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2coc3cc4ccoc4cc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cscn2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2c[nH]c3ccccc23)c(-c2cnccn2)c1 +c1ccc(-c2c[nH]c3nc4occc4nc23)c(-c2cnccn2)c1 +c1ccc(-c2nc3ccccc3s2)c(-c2cnccn2)c1 +c1ccc(-c2nccc3[nH]c4ccncc4c23)c(-c2cnccn2)c1 +c1(c2ncccc2N2c3c(CCc4c2cccc4)cccc3)ncccc1 +c1ccc(-c2ncccc2-c2c3ccoc3cc3ccoc23)nc1 +c1ccc(-c2ncccc2-c2cc3ccccc3[nH]2)nc1 +c1ccc(-c2ncccc2-c2cc3nc4ccoc4nc3[nH]2)nc1 +c1ccc(-c2ncccc2-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)nc1 +c1ccc(-c2ncccc2-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)nc1 +c1ccc(-c2ncccc2-c2ccc3c(c2)oc2ccccc23)nc1 +c1ccc(-c2ncccc2-c2ccc3c(cnc4ccccc43)c2)nc1 +c1ccc(-c2ncccc2-c2ccc3ncsc3c2)nc1 +c1ccc(-c2ncccc2-c2ccc3ocnc3c2)nc1 +c1ccc(-c2ncccc2-c2ccc3sccc3c2)nc1 +c1ccc(-c2ncccc2-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)nc1 +c1ccc(-c2ncccc2-c2cccc3c4ccccc4c4nc[nH]c4c23)nc1 +c1ccc(-c2ncccc2-c2cccc3c4ccccc4c4[nH]cnc4c23)nc1 +c1ccc(-c2ncccc2-c2cccc3c4[nH]cnc4c4ccccc4c23)nc1 +c1ccc(-c2ncccc2-c2coc3cc4[nH]ccc4cc23)nc1 +c1ccc(-c2ncccc2-c2c[nH]c3ccccc23)nc1 +c1ccc(-c2ncccc2-c2nc3ccccc3c3ccccc23)nc1 +c1ccc(-c2ncccc2-n2c3ccncc3c3cnccc32)nc1 +c1ccc(-c2ncccc2-n2ccc3cc4ccoc4cc32)nc1 +c1ccc(-c2nccnc2-c2cc3cc4occc4cc3o2)cc1 +c1ccc(-c2nccnc2-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1 +c1ccc(-c2nccnc2-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)cc1 +c1ccc(-c2nccnc2-c2ccc3c4ccccc4c4nccnc4c3c2)cc1 +c1ccc(-c2nccnc2-c2ccc3[nH]c4ccncc4c3c2)cc1 +c1ccc(-c2nccnc2-c2ccc3[nH]ccc3c2)cc1 +c1ccc(-c2nccnc2-c2cccc3c2sc2ncccc23)cc1 +c1ccc(-c2nccnc2-c2cccc3c4nc[nH]c4c4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2cccc3nn[nH]c23)cc1 +c1ccc(-c2nccnc2-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)cc1 +c1ccc(-c2nccnc2-c2cccc3[nH]c4cnccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccccc2N(c2ccccc2)c2ccccc2)cc1 +c1ccc(-c2nccnc2-c2ccnc3oc4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccnc3sc4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccnc3sc4ncccc4c23)cc1 +c1ccc(-c2nccnc2-c2cncc3c2[nH]c2ccncc23)cc1 +c1ccc(-c2nccnc2-c2cn[nH]c2)cc1 +c1ccc(-c2nccnc2-c2nc3ccccc3c3ccccc23)cc1 +c1ccc(-c2nccnc2-n2c3ccccc3c3cnccc32)cc1 +c1ccc(-c2nccnc2-n2c3ccncc3c3cnccc32)cc1 +c1ccc(-c2nccnc2-n2cnc3nc4nc[nH]c4nc32)cc1 +c1ccc(-c2ncno2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c(-c2cnccn2)c1 +c1ccc(-n2c3ccccc3c3cccnc32)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-n2c3ccccc3c3cnccc32)c(-c2cnccn2)c1 +c1ccc(N(c2ccccc2)c2ccc(-c3cc4nc5cc[nH]c5nc4o3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cc4[nH]c5ccncc5c4cn3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4cnc5ccccc5c4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4nn[nH]c4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4[nH]nnc4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc(-c4cnccn4)c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4c3cnc3ccccc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4ocnc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cncc4c3[nH]c3ccncc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3nccc4[nH]c5ccncc5c34)cc2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c(c3)ncc3ccccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c(c3)sc3ccccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc(-c4cnccn4)c3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4c3[nH]c3ncccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4cnc5ccccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4ncoc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4[nH]c5ncccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4[nH]nnc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cnc4[nH]c5ccccc5c4c3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cncc4[nH]c5ccccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cnoc3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3c[nH]c4ccncc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3ccc4cnccc43)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3cnc4nc5nc[nH]c5nc43)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3nnc4ccccc43)c2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2c3ncoc3nc3ocnc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cc3[nH]c4ccncc4c3cn2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccc3c(c2)[nH]c2cnccc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccc3ccc4cccnc4c3n2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cccc3c2B2c4ccccc4Oc4cccc(c42)O3)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cccc3[nH]c4ncccc4c23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccno2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2coc3cc4ccoc4cc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2coc3nc4[nH]ccc4nc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2nc3nc4nc[nH]c4nc3[nH]2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2nccs2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ncno2)cc1 +c1ccc2c(-c3c4ccoc4cc4ccoc34)coc2c1 +c1ccc2c(-c3c4cc[nH]c4cc4occc34)csc2c1 +c1ccc2c(-c3c4ncoc4nc4ocnc34)csc2c1 +c1ccc2c(-c3c4nc[nH]c4cc4[nH]cnc34)csc2c1 +c1ccc2c(-c3c4[nH]cnc4cc4nc[nH]c34)coc2c1 +c1ccc2c(-c3c4[nH]cnc4nc4nc[nH]c34)csc2c1 +c1ccc2c(-c3cc4cnccc4[nH]3)coc2c1 +c1ccc2c(-c3cc4nc5ccoc5nc4[nH]3)coc2c1 +c1ccc2c(-c3cc4nc5cc[nH]c5nc4o3)coc2c1 +c1ccc2c(-c3cc4nc5cc[nH]c5nc4o3)c[nH]c2c1 +c1ccc2c(-c3ccc(-c4cnccn4)cc3)c[nH]c2c1 +c1ccc2c(-c3ccc4c(c3)c3ccccc3c3nccnc43)csc2c1 +c1ccc2c(-c3ccc4c(c3)sc3ncccc34)csc2c1 +c1ccc2c(-c3ccc4ccsc4c3)csc2c1 +c1ccc2c(-c3ccc4ocnc4c3)c[nH]c2c1 +c1ccc2c(-c3ccc4[nH]c5ncccc5c4c3)c[nH]c2c1 +c1ccc2c(-c3ccc4[nH]nnc4c3)coc2c1 +c1ccc2c(-c3cccc4c3[nH]c3cnccc34)csc2c1 +c1ccc2c(-c3cccc4c3[nH]c3ncccc34)coc2c1 +c1ccc2c(-c3cccc4c3[nH]c3ncccc34)csc2c1 +c1ccc2c(-c3cccc4c5nccnc5c5ccccc5c34)csc2c1 +c1ccc2c(-c3cccc4ocnc34)c[nH]c2c1 +c1ccc2c(-c3cccc4sc5ccccc5c34)coc2c1 +c1ccc2c(-c3ccnc4ncccc34)c[nH]c2c1 +c1ccc2c(-c3ccnnc3)csc2c1 +c1ccc2c(-c3cnc4nccnc4n3)coc2c1 +c1ccc2c(-c3cncs3)c[nH]c2c1 +c1ccc2c(-c3coc4cc5ccoc5cc34)c[nH]c2c1 +c1ccc2c(-c3csc4ccccc34)c[nH]c2c1 +c1ccc2c(-c3cscn3)csc2c1 +c1ccc2c(-c3c[nH]c4nc5occc5nc34)coc2c1 +c1ccc2c(-c3nc4cc5ncoc5nc4o3)c[nH]c2c1 +c1ccc2c(-c3nccc4[nH]ccc34)coc2c1 +c1ccc2c(-n3c4ccccc4c4cccnc43)coc2c1 +c1ccc2c(-n3c4ccccc4c4cccnc43)c[nH]c2c1 +c1ccc2c(-n3c4ccccc4c4cnccc43)csc2c1 +c1ccc2c(-n3ccc4nc5ccoc5nc43)c[nH]c2c1 +c1ccc2c(-n3cnc4nc5nc[nH]c5nc43)coc2c1 +c1ccc2c(-n3cnc4nc5nc[nH]c5nc43)c[nH]c2c1 +c12c(ccnc2)[nH]c(c1)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(c3c(cc(nc3)c3c4c(Sc5c(cccc5)N4)ccc3)[nH]2)cncc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +c12c(cccc2)cnc2c1ccc(c2)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(scc1)cc(cc2)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(c(ccc2)c2c3c(Sc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c1(c2nccnc2)ccccc1c1c2c(Sc3c(cccc3)N2)ccc1 +n1oc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +n1c(csc1)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(ccnc2c2c3c(Sc4c(cccc4)N3)ccc2)[nH]cc1 +c12c(scc1)ccc(c2)c1cc2c(Sc3c(cccc3)N2)cc1 +n1c2c(ncc(c2)c2cc3c(Sc4c(cccc4)N3)cc2)ccc1 +c12c(c3c(c(cnc3)c3cc4c(Sc5c(cccc5)N4)cc3)[nH]2)cncc1 +n1c2c(cc3c(nc(c4cc5c(Sc6c(cccc6)N5)cc4)[nH]3)c2)[nH]c1 +n1c2nc3oc(nc3nc2oc1)c1cc2c(Sc3c(cccc3)N2)cc1 +n1ccsc1c1cc2c(Sc3c(cccc3)N2)cc1 +c12c(c3c(n1c1cc4c(Sc5c(cccc5)N4)cc1)ccnc3)cncc2 +c12nc3c(occ3)nc1[nH]c(c2)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(cc(nc2)c2ccc3c(Sc4c(cccc4)N3)c2)[nH]cc1 +c12c(ccc(c2)c2ccc3c(Sc4c(cccc4)N3)c2)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(c(ccc2)c2ccc3c(Sc4c(cccc4)N3)c2)[nH]c2c1ccnc2 +c12c(cccc2c2ccc3c(Sc4c(cccc4)N3)c2)cnc2c1cccc2 +n1oc(cc1)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(ccnc2)[nH]cc1c1ccc2c(Sc3c(cccc3)N2)c1 +n1c2c(n(c1)c1ccc3c(Sc4c(cccc4)N3)c1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +c1(c2nccnc2)ccc(cc1)c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(cc(cc2)c2c3c(ccc2)Nc2c(S3)cccc2)[nH]c2ncccc12 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +n1c2c(oc1)cccc2c1c2c(ccc1)Nc1c(S2)cccc1 +n1occc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(c3c(c(cnc3)c3c4c(ccc3)Nc3c(S4)cccc3)[nH]2)cncc1 +c12c(ccnc2)[nH]cc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(ccc1)Nc1c(S2)cccc1 +n1cnoc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(n(c3c1ccnc3)c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +n1c2c(nc3c(nco3)c2N2c3c(Sc4c2cccc4)cccc3)oc1 +c12c(cc(nc2)N2c3c(Sc4c2cccc4)cccc3)[nH]cc1 +c12c(cc(cc2)N2c3c(Sc4c2cccc4)cccc3)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)N1c2c(Sc3c1cccc3)cccc2 +n1c2c(nc(cc2)N2c3c(Sc4c2cccc4)cccc3)ccc1 +c12c(sc3c1cccc3N1c3c(Sc4c1cccc4)cccc3)cccc2 +n1c2c(oc1)c(ccc2)N1c2c(Sc3c1cccc3)cccc2 +c12c(nn[nH]2)cccc1N1c2c(Sc3c1cccc3)cccc2 +c12c(cccc2N2c3c(Sc4c2cccc4)cccc3)[nH]c2ncccc12 +c12c(nn[nH]2)c(ccc1)N1c2c(Sc3c1cccc3)cccc2 +c1(c2nccnc2)ccccc1N1c2c(Sc3c1cccc3)cccc2 +c12c(cccc2)[nH]c2ncc(cc12)N1c2c(Sc3c1cccc3)cccc2 +c12nc3c(occ3N3c4c(Sc5c3cccc5)cccc4)nc1[nH]cc2 +c12c(ccnc2N2c3c(Sc4c2cccc4)cccc3)[nH]cc1 +c12nc3c(occ3)nc1n(cc2)N1c2c(Sc3c1cccc3)cccc2 +c1ccc2c(c1)c1cc(-c3c4ccoc4cc4ccoc34)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3c4ccoc4cc4ccoc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3c4ncoc4nc4ocnc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3cc4cnccc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3cc4nc5ccoc5nc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3cc4nc5cc[nH]c5nc4o3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3cc4[nH]ccc4cn3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4nn[nH]c4c3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4[nH]nnc4c3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ccon3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3cnc4nccnc4n3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3cscn3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3nc4nc5ocnc5nc4o3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3nccc4[nH]ccc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ncon3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4ccncc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3ccc4nc5ccoc5nc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3cnc4nc5nc[nH]c5cc43)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-n3cnc4nc5nc[nH]c5nc43)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3c4ccoc4cc4ccoc34)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cc4cnccc4[nH]3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3ccc(-c4cnccn4)cc3)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3ccc4c(c3)[nH]c3cnccc34)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3ccc4sccc4c3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3ccc4[nH]nnc4c3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cncc4c3[nH]c3ccncc34)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3cncs3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cnoc3)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3cnoc3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3coc4cc5ccoc5cc34)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nc4cc5ncoc5nc4o3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nc4nc5nc[nH]c5cc4[nH]3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3nc4nc5ocnc5nc4o3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nccs3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-n3c4ccncc4c4cnccc43)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-n3cnc4nc5nc[nH]c5nc43)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-n3cnc4nc5nc[nH]c5nc43)cc1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c4ncoc4nc4ocnc34)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3c4ncoc4nc4ocnc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c4nc[nH]c4cc4[nH]cnc34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3ccc4ncoc4c3)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3ccc4[nH]nnc4c3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3cncs3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3cscn3)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c[nH]c4ccncc34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3c[nH]c4nc5occc5nc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3nc4cc5ncoc5nc4o3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]c5ccncc5c34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]c5ccncc5c34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]ccc34)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]ccc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3ncon3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-n3cnc4cc5nc[nH]c5cc43)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-n3cnc4nc5nc[nH]c5cc43)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-n3cnc4nc5nc[nH]c5nc43)c1c1[nH]cnc21 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1cc2nc3ccoc3nc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1c[nH]c2ccncc12 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nc2nc3nc[nH]c3nc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nccc2[nH]ccc12 +c1ccc2c(c1)c1ccccc1c1nc(-c3cc4cnccc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3cc4[nH]c5ccncc5c4cn3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3ccc(-c4cnccn4)cc3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3c[nH]c4nc5occc5nc34)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3nc4cc5nc[nH]c5cc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3nc4nc5nc[nH]c5cc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3ncno3)cnc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cc4[nH]ccc4cn3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3ccc4ncoc4c3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3ccc4[nH]nnc4c3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cnc4nccnc4n3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cncc4cc[nH]c34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3coc4nc5[nH]ccc5nc34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3c[nH]c4nc5occc5nc34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3nc4cc5nc[nH]c5cc4[nH]3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3nccc4[nH]c5ccncc5c34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-n3cnc4nc5nc[nH]c5cc43)nc21 +c1ccc2c(c1)c1cccnc1n2-c1cc2cc3occc3cc2o1 +c1ccc2c(c1)c1cccnc1n2-c1cc2nc3cc[nH]c3nc2o1 +c1ccc2c(c1)c1cccnc1n2-c1ccc2sccc2c1 +c1ccc2c(c1)c1cccnc1n2-c1ccn[nH]1 +c1ccc2c(c1)c1cccnc1n2-c1c[nH]c2cc3occc3cc12 +c1ccc2c(c1)c1cccnc1n2-c1c[nH]c2nc3occc3nc12 +c1ccc2c(c1)c1ccncc1n2-c1c2cc[nH]c2cc2occc12 +c1ccc2c(c1)c1ccncc1n2-c1cc2cc3cc[nH]c3cc2o1 +c1ccc2c(c1)c1ccncc1n2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)c1ccncc1n2-c1ccn[nH]1 +c1ccc2c(c1)c1ccncc1n2-c1cc[nH]n1 +c1ccc2c(c1)c1ccncc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)c1ccncc1n2-c1c[nH]c2ccncc12 +c1ccc2c(c1)c1ccncc1n2-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1ccncc1n2-n1c2ccccc2c2cccnc21 +c1ccc2c(c1)c1ccncc1n2-n1ccc2cc3ccoc3cc21 +c1ccc2c(c1)c1cnccc1n2-c1ccc2c(c1)[nH]c1cnccc12 +c1ccc2c(c1)c1cnccc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)c1cnccc1n2-c1nc2nc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1cnccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1ccc2c(c1)c1cnccc1n2-n1cnc2nc3nc[nH]c3nc21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3cc4[nH]ccc4cn3)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3ccc4nn[nH]c4c3)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3nccc4[nH]c5ccncc5c34)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-n3ccc4cnccc43)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-n3cnc4nc5nc[nH]c5cc43)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3cncc4cc[nH]c34)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3cnoc3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3nc4nc5ocnc5nc4o3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3ncno3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-n3c4ccncc4c4cnccc43)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3cc4[nH]ccc4cn3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3ccc4ocnc4c3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3ccc4[nH]c5cnccc5c4c3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3cncc4c3[nH]c3ccncc34)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3coc4cc5ccoc5cc34)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-n3ccc4nc5ccoc5nc43)c21 +c12c(occ1)c(c1c(occ1)c2)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2c(nc3c(nco3)c2c2c3CCc4c(cccc4)Nc3ccc2)oc1 +c12c(cc(nc2)c2c3CCc4c(cccc4)Nc3ccc2)[nH]cc1 +c12c(cccc2)[nH]c2nc(ccc12)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2nc(ccc2ccc1)c1c2CCc3c(cccc3)Nc2ccc1 +c12c(ccc(c2)c2c3CCc4c(cccc4)Nc3ccc2)cnc2c1cccc2 +c12c(ccc(c2)c2c3CCc4c(cccc4)Nc3ccc2)[nH]c2c1ccnc2 +c12nccnc1c(ccc2)c1c2CCc3c(cccc3)Nc2ccc1 +n1cc(sc1)c1c2CCc3c(cccc3)Nc2ccc1 +c12nc3c(occ3c3c4CCc5c(cccc5)Nc4ccc3)nc1[nH]cc2 +n1ccsc1c1c2CCc3c(cccc3)Nc2ccc1 +c12c(n(c3ncccc13)c1c3CCc4c(cccc4)Nc3ccc1)cccc2 +c12c(n(c3c1ccnc3)c1c3CCc4c(cccc4)Nc3ccc1)cccc2 +n1c2c(n(c1)c1c3CCc4c(cccc4)Nc3ccc1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2c(cc3c(nc[nH]3)c2c2cc3CCc4c(cccc4)Nc3cc2)[nH]c1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1cc3CCc5c(cccc5)Nc3cc1)cccc4)cccc2 +c1(c2nccnc2)ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(nc(cc2)c2cc3CCc4c(cccc4)Nc3cc2)ccc1 +c12c(ccc(c2)c2cc3CCc4c(cccc4)Nc3cc2)[nH]c2c1ccnc2 +c12c(ccc(c2)c2cc3CCc4c(cccc4)Nc3cc2)[nH]c2ncccc12 +c12c(cccc2)cnc2c1c(ccc2)c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(nccc2)c(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +c12c(cccc2)[nH]c2nccc(c12)c1cc2CCc3c(cccc3)Nc2cc1 +c12c(occ1)cc1c(occ1c1cc3CCc4c(cccc4)Nc3cc1)c2 +c12c(ccnc2)[nH]cc1c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(cc3c(nc(c4cc5CCc6c(cccc6)Nc5cc4)[nH]3)c2)[nH]c1 +c12c(ccnc2c2cc3CCc4c(cccc4)Nc3cc2)[nH]cc1 +n1ccsc1c1cc2CCc3c(cccc3)Nc2cc1 +c12c(nnn1c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +n1c2c(nc3c(nco3)c2c2ccc3CCc4c(cccc4)Nc3c2)oc1 +c12c(cc(cc2)c2ccc3CCc4c(cccc4)Nc3c2)cnc2c1cccc2 +c12c(cccc2)cnc2c1cccc2c1ccc2CCc3c(cccc3)Nc2c1 +c12c(sc3c1c(ccc3)c1ccc3CCc4c(cccc4)Nc3c1)cccc2 +c12c(cccc2c2ccc3CCc4c(cccc4)Nc3c2)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nccc1c1ccc2CCc3c(cccc3)Nc2c1 +n1occc1c1ccc2CCc3c(cccc3)Nc2c1 +n1occ(c1)c1ccc2CCc3c(cccc3)Nc2c1 +n1c(csc1)c1ccc2CCc3c(cccc3)Nc2c1 +c12nc3c(occ3)nc1[nH]cc2c1ccc2CCc3c(cccc3)Nc2c1 +n1c2c(cc3c(nc(c4ccc5CCc6c(cccc6)Nc5c4)[nH]3)c2)[nH]c1 +n1cnoc1c1ccc2CCc3c(cccc3)Nc2c1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c1 +c12nc3c(oc(c3)c3c4c(CCc5c(cccc5)N4)ccc3)nc1[nH]cc2 +c12c(cc(cc2)c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c12c(scc1)cc(cc2)c1c2c(CCc3c(cccc3)N2)ccc1 +n1c2c(oc1)ccc(c2)c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(ccc(c2)c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c12c(c(ccc2)c2c3c(CCc4c(cccc4)N3)ccc2)cnc2c1cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +c12c(c(ccc2)c2c3c(ccc2)CCc2c(cccc2)N3)[nH]c2c1ccnc2 +c12c(sc3c1c(ccc3)c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +c12c(scc1)cccc2c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(cccc2)c(nc2c1cccc2)c1c2c(CCc3c(cccc3)N2)ccc1 +n1c2nc3nc(c4c5c(CCc6c(cccc6)N5)ccc4)[nH]c3cc2[nH]c1 +c12c(cccc2)[nH]c2c1ccnc2c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(CCc3c(cccc3)N2)ccc1 +n1ccsc1c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)N1c3c(CCc5c1cccc5)cccc3)cccc4)cccc2 +c12nc3c(oc(c3)N3c4c(CCc5c3cccc5)cccc4)nc1[nH]cc2 +n1c2c(nc(cc2)N2c3c(CCc4c2cccc4)cccc3)ccc1 +c12c(nn[nH]2)cc(cc1)N1c2c(CCc3c1cccc3)cccc2 +c12c(sc3c1cccc3N1c3c(CCc4c1cccc4)cccc3)cccc2 +c12c(c(ccc2)N2c3c(CCc4c2cccc4)cccc3)[nH]c2ncccc12 +c12c(cccc2N2c3c(CCc4c2cccc4)cccc3)[nH]c2ncccc12 +n1oc(cc1)N1c2c(CCc3c1cccc3)cccc2 +n1c2c(cc3c(nc([nH]3)N3c4c(CCc5c3cccc5)cccc4)c2)[nH]c1 +c12c(cccc2)[nH]c2c1ccnc2N1c2c(CCc3c1cccc3)cccc2 +c12c(c3c(ccnc3)[nH]2)c(ncc1)N1c2c(CCc3c1cccc3)cccc2 +c12c(n(c3c1ccnc3)N1c3c(CCc4c1cccc4)cccc3)cccc2 +c1ccc2c(c1)ccn2-c1c2nc[nH]c2cc2[nH]cnc12 +c1ccc2c(c1)ccn2-c1c2[nH]cnc2cc2nc[nH]c12 +c1ccc2c(c1)ccn2-c1c2[nH]cnc2nc2nc[nH]c12 +c1ccc2c(c1)ccn2-c1ccc2[nH]c3cnccc3c2c1 +c1ccc2c(c1)ccn2-c1cccc2c1sc1ccccc12 +c1ccc2c(c1)ccn2-c1cccc2ocnc12 +c1ccc2c(c1)ccn2-c1cccc2sc3ccccc3c12 +c1ccc2c(c1)ccn2-c1ccno1 +c1ccc2c(c1)ccn2-c1cnc2ccccc2n1 +c1ccc2c(c1)ccn2-c1cnc2[nH]c3ccccc3c2c1 +c1ccc2c(c1)ccn2-c1coc2nc3[nH]ccc3nc12 +c1ccc2c(c1)ccn2-c1nccc2c1[nH]c1ccccc12 +c1ccc2c(c1)cnc1c(-c3cc4[nH]c5ccccc5c4cn3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4c(c3)sc3ccccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4ccsc4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4cc[nH]c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4oc5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4scnc4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cccc4c3[nH]c3ncccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3cccc4c5ccccc5c5nccnc5c34)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4sc5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4[nH]c5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cn[nH]c3)cccc12 +c1ccc2c(c1)cnc1c(-c3coc4ccccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc12 +c1ccc2c(c1)cnc1c(-n3ccc4nc5ccoc5nc43)cccc12 +c1ccc2c(c1)cnc1cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cc4cccnc4c4ncccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3ccncc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c5c3CCCN5CCC4)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ccoc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ccsc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4sccc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]nnc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c3sc3ncccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c3[nH]c3cnccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c5ccccc5c5[nH]cnc5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cnc4c5ccccc5c5ccccc5c4n3)ccc12 +c1ccc2c(c1)cnc1cc(-c3cnc4sc5ncccc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1ccc2c(c1)cnc1cc(-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)ccc12 +c1ccc2c(c1)cnc1cc(-n3cnc4c5ccccc5c5ccccc5c43)ccc12 +c1ccc2c(c1)cnc1ccc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4c(cnc5ccccc54)c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4nn[nH]c4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4occc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4ocnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4[nH]ccc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4c3cnc3ccccc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4ncsc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4sc5ccccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4[nH]c5ncccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnc4c3ccc3cccnc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnc4sc5ccccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnnc3)cc12 +c1ccc2c(c1)cnc1ccc(-c3nc4cc5scnc5cc4s3)cc12 +c1ccc2c(c1)cnc1ccc(-c3nccs3)cc12 +c1ccc2c(c1)cnc1ccc(-n3ccc4cnccc43)cc12 +c1ccc2c(c1)cnc1ccc(-n3cnc4cc5nc[nH]c5cc43)cc12 +c1ccc2c(c1)cnc1cccc(-c3cc4cc5ccoc5cc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3cc4nc5ccoc5nc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4c(c3)sc3ccccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4c(n3)sc3ncccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4[nH]c5ccncc5c4c3)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4[nH]nnc4c3)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c5ccccc5c5nccnc5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4ncc5ccccc5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4occc34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4[nH]ccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccnc4cccnc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccno3)c12 +c1ccc2c(c1)cnc1cccc(-c3cn[nH]c3)c12 +c1ccc2c(c1)cnc1cccc(-c3coc4cc5ccoc5cc34)c12 +c1ccc2c(c1)cnc1cccc(-c3coc4cc5[nH]ccc5cc34)c12 +c1ccc2c(c1)cnc1cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3nc4cc5scnc5cc4s3)c12 +c1ccc2c(c1)cnc1cccc(-n3cnc4c5ccccc5c5ccccc5c43)c12 +c1ccc2c(c1)nc(-c1c3cc[nH]c3cc3occc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3ncoc3nc3ocnc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3ncsc3cc3ncsc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3nc[nH]c3cc3[nH]cnc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cc3c4ccccc4[nH]c3c3c1[nH]c1ccccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cc3nc4cc[nH]c4nc3o1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3c(c1)c1ccccc1c1nccnc31)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3c(c1)[nH]c1c3ccc3[nH]c4ccccc4c31)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3nccnc3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3nn[nH]c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3oc4ccccc4c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3c1[nH]c1ccncc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3c4ccccc4c4nc[nH]c4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3occc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3sccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3[nH]c4ncccc4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1ccnc3oc4ccccc4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1cnc3[nH]c4ccccc4c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1cncc3c1[nH]c1ccccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cn[nH]c1)c1ccccc12 +c1ccc2c(c1)nc(-n1c3ccncc3c3cnccc31)c1ccccc12 +c1ccc2c(c1)ncc1c(-c3c4ccoc4cc4ccoc34)cccc12 +c1ccc2c(c1)ncc1c(-c3c4ncoc4nc4ocnc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cc4cc5occc5cc4o3)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4c(n3)[nH]c3ccccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4nccnc4c3)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4ocnc4c3)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3oc3ncccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3sc3ncccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4[nH]nnc34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccnc4sc5ccccc5c34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccnc4sc5ncccc5c34)cccc12 +c1ccc2c(c1)ncc1c(-c3cc[nH]n3)cccc12 +c1ccc2c(c1)ncc1c(-c3cnoc3)cccc12 +c1ccc2c(c1)ncc1c(-c3cscn3)cccc12 +c1ccc2c(c1)ncc1c(-c3c[nH]c4ccccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3nc4cc5nc[nH]c5cc4[nH]3)cccc12 +c1ccc2c(c1)ncc1c(-c3nccs3)cccc12 +c1ccc2c(c1)ncc1c(-n3c4ccccc4c4c5ccccc5[nH]c43)cccc12 +c1ccc2c(c1)ncc1c(-n3c4ccccc4c4cccnc43)cccc12 +c1ccc2c(c1)ncc1c(-n3ccc4cc5ccoc5cc43)cccc12 +c1ccc2c(c1)ncc1c(-n3cnc4c5ccccc5c5ccccc5c43)cccc12 +c1ccc2c(c1)ncc1cc(-c3c4ccoc4cc4ccoc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3c4ncoc4cc4ncoc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3cc4[nH]c5ccccc5c4cn3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(c3)sc3ncccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(cnc5ccccc54)c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c5c3CCCN5CCC4)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]ccc4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3cccc4[nH]ccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccnc4sc5ccccc5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccnc4[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccon3)ccc12 +c1ccc2c(c1)ncc1cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +c1ccc2c(c1)ncc1ccc(-c3c4[nH]ccc4cc4ccoc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4ccsc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4ncsc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4occc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5ncccc5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3sc3ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3[nH]c3cnccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3[nH]c3ncccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccnc4oc5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cnc4c5ccccc5c5ccccc5c4n3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncc4c3[nH]c3ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncc4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncs3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cnoc3)cc12 +c1ccc2c(c1)ncc1ccc(-c3coc4ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3c[nH]c4ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ncno3)cc12 +c1ccc2c(c1)ncc1ccc(-n3c4ccccc4c4c5ccccc5[nH]c43)cc12 +c1ccc2c(c1)ncc1ccc(-n3c4ccccc4c4cccnc43)cc12 +c1ccc2c(c1)nnn2-c1cc2c3c(c1)CCCN3CCC2 +c1ccc2c(c1)nnn2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)nnn2-c1ccc2c(c1)sc1ccccc12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1ccc3c4ccccc4[nH]c3c12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1cnccc12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1ncccc12 +c1ccc2c(c1)nnn2-c1ccc2cc[nH]c2c1 +c1ccc2c(c1)nnn2-c1ccc2ncoc2c1 +c1ccc2c(c1)nnn2-c1ccc2nn[nH]c2c1 +c1ccc2c(c1)nnn2-c1ccc2oc3ncccc3c2c1 +c1ccc2c(c1)nnn2-c1ccc2sc3ncccc3c2c1 +c1ccc2c(c1)nnn2-c1ccc2scnc2c1 +c1ccc2c(c1)nnn2-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +c1ccc2c(c1)nnn2-c1cccc2c1[nH]c1[nH]c3ccccc3c12 +c1ccc2c(c1)nnn2-c1cccc2c3ccccc3c3[nH]cnc3c12 +c1ccc2c(c1)nnn2-c1cccc2c3nc[nH]c3c3ccccc3c12 +c1ccc2c(c1)nnn2-c1cccc2[nH]c3ccncc3c12 +c1ccc2c(c1)nnn2-c1cnc2[nH]c3ccccc3c2c1 +c1ccc2c(c1)nnn2-c1cncc2[nH]c3ccccc3c12 +c1ccc2c(c1)nnn2-c1coc2cc3ccoc3cc12 +c1ccc2c(c1)nnn2-c1csc2ccccc12 +c1ccc2c(c1)nnn2-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)nnn2-c1nc2cc3ocnc3cc2o1 +c1ccc2c(c1)nnn2-c1nccc2[nH]ccc12 +c1ccc2c(c1)nnn2-n1c2ccccc2c2c3[nH]c4ccccc4c3ccc21 +c1ccc2c(c1)nnn2-n1cccn1 +c1ccc2c(c1)nnn2-n1cnc2c3ccccc3c3ccccc3c21 +c1ccc2c(c1)nnn2-n1cnc2nc3nc[nH]c3nc21 +c1ccc2c(c1)oc1c(-c3c4ncoc4nc4ocnc34)cccc12 +c1ccc2c(c1)oc1c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc12 +c1ccc2c(c1)oc1c(-c3c4[nH]cnc4nc4nc[nH]c34)cccc12 +c1ccc2c(c1)oc1c(-c3cc4[nH]c5ccncc5c4cn3)cccc12 +c1ccc2c(c1)oc1c(-c3ccc4nn[nH]c4c3)cccc12 +c1ccc2c(c1)oc1c(-c3cncc4c3[nH]c3ccncc34)cccc12 +c1ccc2c(c1)oc1c(-c3csc4ccccc34)cccc12 +c1ccc2c(c1)oc1c(-c3c[nH]c4nc5occc5nc34)cccc12 +c1ccc2c(c1)oc1c(-n3ccc4cnccc43)cccc12 +c1ccc2c(c1)oc1cc(-c3cc4cnccc4[nH]3)ccc12 +c1ccc2c(c1)oc1cc(-c3ccc(-c4cnccn4)cc3)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccc4c(n3)oc3ccccc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4c5c3CCCN5CCC4)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4c5ccccc5c5[nH]cnc5c4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4oc5ncccc5c4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4ocnc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4scnc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3ccc4[nH]c5ncccc5c4c3)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccc4[nH]ccc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cccc4ccsc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3ccnc4ncccc34)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccnc4oc5ccccc5c34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cc[nH]n3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3cncs3)ccc12 +c1ccc2c(c1)Oc1cc(-c3cn[nH]c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3csc4ccccc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3c[nH]c4nc5occc5nc34)ccc12 +c1ccc2c(c1)oc1cc(-c3nc4cc5nc[nH]c5cc4[nH]3)ccc12 +c1ccc2c(c1)oc1cc(-c3ncon3)ccc12 +c1ccc2c(c1)oc1cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +c1ccc2c(c1)Oc1ccc(-c3c4ncoc4cc4ncoc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3c4ncoc4nc4ocnc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3c4[nH]cnc4nc4nc[nH]c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cc4c5c(c3)Oc3ccccc3B5c3ccccc3O4)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cc4cc5ccoc5cc4[nH]3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)oc1ccc(-c3cc4cnccc4[nH]3)cc12 +c1ccc2c(c1)oc1ccc(-c3cc4[nH]c5ccncc5c4cn3)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3ccc4ccoc4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3ccc4ncc5ccccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccc4sccc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3ccc4[nH]c5cnccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccc4[nH]c5ncccc5c4c3)cc12 +c1ccc2c(c1)oc1ccc(-c3cccc4c3[nH]c3cnccc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3cccc4c3[nH]c3cnccc34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cccc4ncc5ccccc5c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cccc4ncoc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cccc4nn[nH]c34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3cccc4sc5ccccc5c34)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccnc4cccnc34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3ccnc4sc5ncccc5c34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccno3)cc12 +c1ccc2c(c1)Oc1ccc(-c3cc[nH]n3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cnc4cccnc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4ncccc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4nccnc4n3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4sc5ccccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cnc4[nH]c5ccccc5c4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3c[nH]c4nc5occc5nc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3c[nH]c4nc5occc5nc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3nc4ccccc4s3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3nccc4c3[nH]c3ccccc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3nccc4[nH]ccc34)cc1O2 +c1ccc2c(c1)oc1ccc(-c3ncno3)cc12 +c1ccc2c(c1)Oc1ccc(-n3c4ccncc4c4cnccc43)cc1O2 +c1ccc2c(c1)oc1cccc(-c3c4ccoc4cc4ccoc34)c12 +c1ccc2c(c1)Oc1cccc(-c3cc4nc5cc[nH]c5nc4o3)c1O2 +c1ccc2c(c1)oc1cccc(-c3cc4[nH]c5ccncc5c4cn3)c12 +c1ccc2c(c1)oc1cccc(-c3cc4[nH]ccc4cn3)c12 +c1ccc2c(c1)Oc1cccc(-c3ccc4c(n3)[nH]c3ccccc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccc4ccsc4c3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccc4ncc5ccccc5c4c3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)Oc1cccc(-c3ccc4[nH]c5cnccc5c4c3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cccc4ocnc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cccc4sccc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccccc3-c3cnccn3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ccnc4ncccc34)c12 +c1ccc2c(c1)oc1cccc(-c3ccon3)c12 +c1ccc2c(c1)Oc1cccc(-c3cncc4c3[nH]c3ccncc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cscn3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3nc4nc5nc[nH]c5cc4[nH]3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3nc4nc5ocnc5nc4o3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ncon3)c12 +c1ccc2c(c1)oc1cccc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)Oc1cccc(-n3cnc4nc5nc[nH]c5nc43)c1O2 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cc2c(cn1)[nH]c1ccccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cc2ccccc2o1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2c(c1)[nH]c1c2ccc2[nH]c4ccccc4c21)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2nn[nH]c2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2oc4ccccc4c2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2[nH]ccc2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c1oc1ccccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c1oc1ncccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c4ccccc4c4nc[nH]c4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2oc4ncccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2[nH]c4cnccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2[nH]c4[nH]c5ccccc5c4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccccc1-c1cc2c4c(c1)CCCN4CCC2)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccnc2sc4ncccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cn[nH]c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1c[nH]c2cc4occc4cc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-n1c2ccccc2c2cnccc21)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(c2)oc2ccccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(n2)sc2ccccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(n2)sc2ncccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4ncsc4c2)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4c5ccccc5c5nc[nH]c5c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4ncc5ccccc5c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4nn[nH]c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2coc4cc5ccoc5cc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4cc5ccoc5cc4[nH]2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4cc5occc5cc4o2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4ccccc4s2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2ccc4c(c2)[nH]c2[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2ncc2ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2oc2ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2[nH]c2c4ccc4[nH]c5ccccc5c42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2[nH]c2ccncc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c5ccccc5c5nc[nH]c5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc[nH]n2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cncc4[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2coc4cc5ccoc5cc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2coc4ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2nc4ccccc4s2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2c4ccccc4c4c5ccccc5[nH]c42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2c4ccncc4c4cnccc42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2ccc4nc5ccoc5nc42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccc4c(c2)[nH]c2c4ccc4[nH]c5ccccc5c42)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4oc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4ocnc24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4sc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4[nH]ccc24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccnc4sc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cc[nH]n2)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2nccc4[nH]c5ccccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-n2c4ccncc4c4cnccc42)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-n2cnc4c5ccccc5c5ccccc5c42)c1O3 +c1ccc2c(c1)oc1nc(-c3cc4cnccc4[nH]3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc(-c4cnccn4)cc3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4sc5ccccc5c4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4[nH]c5ncccc5c4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3cccc4c3sc3ccccc34)ccc12 +c1ccc2c(c1)oc1nc(-c3nccs3)ccc12 +c1ccc2c(c1)oc1ncc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)oc1ncc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)oc1ncc(-c3cc4nc5ccoc5nc4[nH]3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccc4[nH]c5cnccc5c4c3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccno3)cc12 +c1ccc2c(c1)oc1ncc(-c3cnc4nccnc4n3)cc12 +c1ccc2c(c1)oc1ncc(-c3nc4cc5ncoc5nc4o3)cc12 +c1ccc2c(c1)oc1ncc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)oc1ncc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)oc1nccc(-c3c4[nH]cnc4nc4nc[nH]c34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4c(c3)[nH]c3ncccc34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4ocnc4c3)c12 +c1ccc2c(c1)oc1nccc(-c3cncc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)oc1nccc(-c3ncno3)c12 +c1ccc2c(c1)oc1nccc(-n3ccc4nc5ccoc5nc43)c12 +c1ccc2c(c1)oc1nccc(-n3cnc4cc5nc[nH]c5cc43)c12 +c1ccc2c(c1)sc1c(-c3c4[nH]ccc4cc4ccoc34)cccc12 +c1ccc2c(c1)sc1c(-c3cc4c5c(c3)CCCN5CCC4)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4c(c3)c3ccccc3c3nccnc43)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4ccoc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4occc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4[nH]nnc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3cccc4c3[nH]c3ccncc34)cccc12 +c1ccc2c(c1)sc1c(-c3cc[nH]n3)cccc12 +c1ccc2c(c1)sc1c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +c1ccc2c(c1)sc1c(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cccc12 +c1ccc2c(c1)sc1c(-c3nc4cc5scnc5cc4s3)cccc12 +c1ccc2c(c1)sc1c(-c3nccc4[nH]c5ccncc5c34)cccc12 +c1ccc2c(c1)sc1c(-n3c4ccccc4c4ccncc43)cccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ccsc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4nn[nH]c4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4scnc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4[nH]ccc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)ccc12 +c1ccc2c(c1)sc1cc(-c3cccc4c5[nH]cnc5c5ccccc5c34)ccc12 +c1ccc2c(c1)sc1cc(-c3cn[nH]c3)ccc12 +c1ccc2c(c1)sc1cc(-c3nccc4[nH]c5ccncc5c34)ccc12 +c1ccc2c(c1)sc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4c(n3)sc3ccccc34)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4c(n3)sc3ncccc34)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4[nH]c5ccncc5c4c3)cc12 +c1ccc2c(c1)sc1ccc(-c3cccc4c5nc[nH]c5c5ccccc5c34)cc12 +c1ccc2c(c1)sc1ccc(-n3c4ccncc4c4cnccc43)cc12 +c1ccc2c(c1)sc1cccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)c12 +c1ccc2c(c1)sc1cccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)sc1cccc(-c3cccc4c5nccnc5c5ccccc5c34)c12 +c1ccc2c(c1)sc1cccc(-c3c[nH]c4nc5occc5nc34)c12 +c1ccc2c(c1)sc1cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c12 +c1ccc2c(c1)sc1cccc(-n3c4ccncc4c4cnccc43)c12 +c1ccc2c(c1)sc1nc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +c1ccc2c(c1)sc1nc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)sc1nc(-c3ccc4[nH]nnc4c3)ccc12 +c1ccc2c(c1)sc1nc(-c3ccno3)ccc12 +c1ccc2c(c1)sc1nc(-c3cnc4nccnc4n3)ccc12 +c1ccc2c(c1)sc1nc(-c3cnoc3)ccc12 +c1ccc2c(c1)sc1nc(-c3nc4nc5nc[nH]c5nc4[nH]3)ccc12 +c1ccc2c(c1)sc1nc(-c3nccc4[nH]c5ccncc5c34)ccc12 +c1ccc2c(c1)sc1nc(-c3nccc4[nH]ccc34)ccc12 +c1ccc2c(c1)sc1ncc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)sc1ncc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)sc1ncc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)sc1ncc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)sc1ncc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)sc1ncc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)sc1ncc(-c3ncno3)cc12 +c1ccc2c(c1)sc1ncc(-n3cnc4cc5nc[nH]c5cc43)cc12 +c1ccc2c(c1)sc1ncc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)sc1nccc(-c3c4nc[nH]c4cc4[nH]cnc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccc(-c4cnccn4)cc3)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4ocnc4c3)c12 +c1ccc2c(c1)sc1nccc(-c3cccc4c3[nH]c3ncccc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccon3)c12 +c1ccc2c(c1)sc1nccc(-c3cnc4nccnc4n3)c12 +c1ccc2c(c1)sc1nccc(-c3nc4cc5ncoc5nc4o3)c12 +c1ccc2c(c1)sc1nccc(-n3c4ccccc4c4ccncc43)c12 +c1ccc2c(c1)sc1nccc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)sc1nccc(-n3cnc4nc5nc[nH]c5nc43)c12 +c1ccc2c(c1)[nH]c1c(-c3c4cc[nH]c4cc4occc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cc4cc5occc5cc4o3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cc4[nH]ccc4cn3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4c(c3)[nH]c3ncccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4c(n3)sc3ccccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4ccoc4c3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4ccsc4c3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4[nH]nnc4c3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4c3[nH]c3ncccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4c5[nH]cnc5c5ccccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4[nH]c5ncccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccnc4oc5ccccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccnc4[nH]c5ccccc5c34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3ccnnc3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cncs3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3coc4cc5[nH]ccc5cc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3coc4nc5[nH]ccc5nc34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3cscn3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3c[nH]c4ccncc34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3c[nH]c4nc5occc5nc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nc4cc5nc[nH]c5cc4[nH]3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3nc4cc5ocnc5cc4o3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nc4nc5nc[nH]c5cc4[nH]3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nccs3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3nccs3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ncon3)cncc12 +c1ccc2c(c1)[nH]c1c(-n3cnc4nc5nc[nH]c5cc43)nccc12 +c1ccc2c(c1)[nH]c1c2c(-c2c3[nH]cnc3cc3nc[nH]c23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2ccc3ccsc3c2)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2cccc3c2sc2ccccc23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2cccc3[nH]c4ncccc4c23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2nccs2)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-n2ccc3cnccc32)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-n2cnc3nc4nc[nH]c4nc32)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1c2[nH]cnc2nc2nc[nH]c12 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1ccno1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1ccon1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cnc2nccnc2n1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cncc2c1[nH]c1ccncc12 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cscn1 +c1ccc2c(c1)[nH]c1c2cc(-c2c3[nH]cnc3cc3nc[nH]c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3c(c2)[nH]c2cnccc23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3c(c2)[nH]c2ncccc23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3ccsc3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3nccnc3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3nn[nH]c3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccnc3[nH]c4ccccc4c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2cncc3cc[nH]c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-n2cnc3nc4nc[nH]c4nc32)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccc2[nH]nnc2c1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cccc2c1sc1ccccc12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccnc2ncccc12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccno1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cncs1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1nc2nc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1nc2nc3ocnc3nc2o1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ncon1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-n1cnc2cc3nc[nH]c3cc21 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4c5ncoc5nc5ocnc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ccc5c(c4)sc4ccccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ccc5sccc5c4)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4cccc5c4[nH]c4cnccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4cccc5[nH]c6cnccc6c45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4csc5ccccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4c[nH]c5ccncc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ncno4)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-n4ccc5nc6ccoc6nc54)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cc5cc6occc6cc5o4)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cccc5ocnc45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cccc5[nH]c6cnccc6c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4ccnc5ncccc45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4ccnc5[nH]c6ccccc6c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cncc5cc[nH]c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4nccs4)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-n4c5ccncc5c5cnccc54)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4c5ccoc5cc5ccoc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4ccc5[nH]c6cnccc6c5c4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5c4[nH]c4ncccc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5sc6ccccc6c45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5[nH]c6ncccc6c45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cncc5c4[nH]c4ccncc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cncs4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cnoc4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cscn4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4nc5nc6nc[nH]c6cc5[nH]4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4ncon4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-n4c5ccccc5c5ccncc54)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-n4ccc5nc6ccoc6nc54)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cc5nc6ccoc6nc5[nH]4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4ccc5ccsc5c4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4ccc5ncoc5c4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cccc5c4[nH]c4ncccc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cncc5c4[nH]c4ccncc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4csc5ccccc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-n4cnc5nc6nc[nH]c6nc54)c3c21 +c1ccc2c(c1)[nH]c1cc(-c3cc4cc5occc5cc4o3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3ccc4ncoc4c3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3ccc4ocnc4c3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3cncc4cc[nH]c34)ncc12 +c1ccc2c(c1)[nH]c1cc(-n3c4ccccc4c4ccncc43)ncc12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5cc6[nH]ccc6cn5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccc6c(c5)[nH]c5cnccc56)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccc6ccsc6c5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccno5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccon5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5nccs5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cc6nc7ccoc7nc6[nH]5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5ccc6ccsc6c5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5sc5ccccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5[nH]c5cnccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5[nH]c5ncccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cnoc5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5nc6nc7nc[nH]c7nc6[nH]5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5nccc6[nH]c7ccncc7c56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5ncon5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-n5cnc6nc7nc[nH]c7cc65)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5cccc6sccc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5cncc6c5[nH]c5ccncc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5coc6cc7ccoc7cc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-n5c6ccncc6c6cnccc65)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-n5ccc6cnccc65)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5c6nc[nH]c6cc6[nH]cnc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5c6[nH]cnc6nc6nc[nH]c56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6c(c5)sc5ccccc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6nn[nH]c6c5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6[nH]nnc6c5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5cccc6sccc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5coc6nc7[nH]ccc7nc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ncno5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-n5cnc6cc7nc[nH]c7cc65)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-n5cnc6nc7nc[nH]c7cc65)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4c5ncoc5nc5ocnc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4cc5cnccc5[nH]4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5c(c4)[nH]c4cnccc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5[nH]c6ncccc6c5c4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5[nH]nnc5c4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4csc5ccccc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-n4cnc5cc6nc[nH]c6cc54)c3c12 +c1ccc2c(c1)[nH]c1ccnc(-c3c4nc[nH]c4cc4[nH]cnc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cccc4c3sc3ccccc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cccc4[nH]c5cnccc5c34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccnc4[nH]c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccno3)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cscn3)c12 +c1ccc2c(c1)[nH]c1ccnc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)[nH]c1cnc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cc4c5c(c3)CCCN5CCC4)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)oc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)sc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)sc3ncccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(n3)[nH]c3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c5ccccc5c5nccnc5c4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4ccsc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4sc5ccccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4sccc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4c3oc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccnc4sc5ncccc5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cnc4nccnc4n3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ncno3)cc12 +c1ccc2c(c1)[nH]c1cnc(-n3c4ccncc4c4cnccc43)cc12 +c1ccc2c(c1)[nH]c1cnc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)[nH]c1cncc(-c3c4ncoc4nc4ocnc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cc4cc5occc5cc4o3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cc4[nH]ccc4cn3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4c(c3)sc3ccccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4ccsc4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4cc[nH]c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4oc5ccccc5c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4[nH]c5ccncc5c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4[nH]ccc4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cccc4c3[nH]c3ncccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cccc4scnc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cncs3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3csc4ccccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cscn3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3nc4nc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)[nH]c1cncc(-n3c4ccccc4c4cccnc43)c12 +c1ccc2c(c1)[nH]c1cncc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4c(n3)sc3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4oc5ncccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4c3oc3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4occc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4ocnc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccnc4sc5ncccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cnc4sc5ccccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cnc4sc5ncccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3nccc4c3[nH]c3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3nccc4[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)ccc12 +c1ccc2c(c1)[nH]c1ncc(-c3c4ncoc4cc4ncoc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c(c3)[nH]c3ccncc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c5ccccc5c5nccnc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4ncsc4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4sc5ncccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cnc4oc5ccccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cncc4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cn[nH]c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3coc4nc5[nH]ccc5nc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-n3ccc4nc5ccoc5nc43)cc12 +c1ccc2c(c1)[nH]c1ncc(-n3cccn3)cc12 +c1ccc2c(c1)[nH]c1nccc(-c3cc4cc5occc5cc4o3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4cc[nH]c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c3oc3ccccc34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4occc34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4[nH]c5cnccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cnc4oc5ccccc5c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cncc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)[nH]c1nccc(-n3c4ccccc4c4c5ccccc5[nH]c43)c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4c5[nH]cnc5cc5nc[nH]c45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cc5cnccc5[nH]4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4ccc5c(c4)[nH]c4cnccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4ccc5c(c4)[nH]c4ncccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cccc5sccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4coc5nc6[nH]ccc6nc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cscn4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4nc5nc6nc[nH]c6cc5[nH]4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4cc5[nH]ccc5cn4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5c(c4)sc4ccccc45)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5nn[nH]c5c4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5[nH]c6ncccc6c5c4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4coc5cc6ccoc6cc45)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5cc6ncoc6nc5o4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5cc6nc[nH]c6cc5[nH]4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5nc6nc[nH]c6cc5[nH]4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nc5cc6nc[nH]c6cc5[nH]4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nc5nc6ocnc6nc5o4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nccs4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4ncon4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-n4c5ccccc5c5cccnc54)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5nccnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5ocnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5[nH]nnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4cnoc4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4coc5nc6[nH]ccc6nc45)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-n4c5ccncc5c5cnccc54)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-n4cnc5nc6nc[nH]c6cc54)c3c12 +c1ccc2nc(-c3ccc4c5ccccc5c5nccnc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4cnc5ccccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4ncsc4c3)cnc2c1 +c1ccc2nc(-c3ccc4oc5ccccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4sc5ncccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4[nH]ccc4c3)cnc2c1 +c1ccc2nc(-c3cccc4c3sc3ncccc34)cnc2c1 +c1ccc2nc(-c3cccc4c3[nH]c3cnccc34)cnc2c1 +c1ccc2nc(-c3cccc4ncoc34)cnc2c1 +c1ccc2nc(-c3cccc4ocnc34)cnc2c1 +c1ccc2nc(-c3cccc4[nH]c5cnccc5c34)cnc2c1 +c1ccc2nc(-c3coc4cc5[nH]ccc5cc34)cnc2c1 +c1ccc2nc(-c3c[nH]c4cc5occc5cc34)cnc2c1 +c1ccc2nc(-n3c4ccccc4c4cnccc43)cnc2c1 +c1ccc2nc(-n3ccc4cc5ccoc5cc43)cnc2c1 +c1ccc2nc(-n3cccn3)cnc2c1 +c1ccc2oc(-c3c4nc[nH]c4cc4[nH]cnc34)cc2c1 +c1ccc2oc(-c3cc4c(cn3)[nH]c3ccccc34)cc2c1 +c1ccc2oc(-c3cc4c(cn3)[nH]c3ccccc34)nc2c1 +c1ccc2oc(-c3cc4cc5occc5cc4o3)cc2c1 +c1ccc2oc(-c3cc4nc5ccoc5nc4[nH]3)nc2c1 +c1ccc2oc(-c3ccc(-c4cnccn4)cc3)nc2c1 +c1ccc2oc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)nc2c1 +c1ccc2oc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)nc2c1 +c1ccc2oc(-c3ccc4c(c3)[nH]c3cnccc34)nc2c1 +c1ccc2oc(-c3ccc4c(n3)oc3ccccc34)nc2c1 +c1ccc2oc(-c3ccc4c(n3)sc3ncccc34)nc2c1 +c1ccc2oc(-c3ccc4ccsc4c3)nc2c1 +c1ccc2oc(-c3ccc4cc[nH]c4c3)nc2c1 +c1ccc2oc(-c3ccc4cnc5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3ccc4ncccc4n3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5cnccc5c4c3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5ncccc5c4c3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)nc2c1 +c1ccc2oc(-c3cccc4c5nc[nH]c5c5ccccc5c34)nc2c1 +c1ccc2oc(-c3cccc4oc5ccccc5c34)nc2c1 +c1ccc2oc(-c3cccc4ocnc34)nc2c1 +c1ccc2oc(-c3cccc4sccc34)nc2c1 +c1ccc2oc(-c3cccc4[nH]c5ccncc5c34)nc2c1 +c1ccc2oc(-c3cccc4[nH]c5ncccc5c34)cc2c1 +c1ccc2oc(-c3cccc4[nH]c5ncccc5c34)nc2c1 +c1ccc2oc(-c3ccn[nH]3)nc2c1 +c1ccc2oc(-c3cnc4ccccc4n3)cc2c1 +c1ccc2oc(-c3cnc4oc5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3cnc4[nH]c5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3c[nH]c4ccccc34)nc2c1 +c1ccc2oc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)nc2c1 +c1ccc2oc(-c3ncon3)cc2c1 +c1ccc2oc(-n3cnc4nc5nc[nH]c5cc43)cc2c1 +c1ccc2oc(-n3nnc4ccccc43)nc2c1 +c1ccc2sc(-c3c4ncoc4cc4ncoc34)cc2c1 +c1ccc2sc(-c3ccc4c(c3)oc3ncccc34)cc2c1 +c1ccc2sc(-c3ccc4c(c3)sc3ncccc34)cc2c1 +c1ccc2sc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)cc2c1 +c1ccc2sc(-c3ccc4[nH]nnc4c3)nc2c1 +c1ccc2sc(-c3cccc4c3sc3ccccc34)nc2c1 +c1ccc2sc(-c3cccc4occc34)cc2c1 +c1ccc2sc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)cc2c1 +c1ccc2sc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc2c1 +c1ccc2sc(-c3ccnc4sc5ncccc5c34)cc2c1 +c1ccc2sc(-c3cnc4c5ccccc5c5ccccc5c4n3)cc2c1 +c1ccc2sc(-c3cnc4cccnc4c3)cc2c1 +c1ccc2sc(-c3c[nH]c4ccccc34)cc2c1 +c1ccc2sc(-c3c[nH]c4ccncc34)nc2c1 +c1ccc2sc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cc2c1 +c1ccc2sc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc2c1 +c1ccc2sc(-c3nc4nc5nc[nH]c5nc4[nH]3)nc2c1 +c1ccc2sc(-c3nccc4[nH]ccc34)cc2c1 +c1ccc2sc(-n3ccc4cc5ccoc5cc43)cc2c1 +c1ccc2[nH]c(-c3c4ncoc4nc4ocnc34)cc2c1 +c1ccc2[nH]c(-c3cc4cccnc4c4ncccc34)cc2c1 +c1ccc2[nH]c(-c3cc4cnccc4[nH]3)cc2c1 +c1ccc2[nH]c(-c3cc4nc5ccoc5nc4[nH]3)cc2c1 +c1ccc2[nH]c(-c3ccc(-c4cnccn4)cc3)cc2c1 +c1ccc2[nH]c(-c3ccc4c(cnc5ccccc54)c3)cc2c1 +c1ccc2[nH]c(-c3ccc4ocnc4c3)cc2c1 +c1ccc2[nH]c(-c3cccc4c3[nH]c3cnccc34)cc2c1 +c1ccc2[nH]c(-c3cccc4c3[nH]c3ncccc34)cc2c1 +c1ccc2[nH]c(-c3cccc4[nH]c5cnccc5c34)cc2c1 +c1ccc2[nH]c(-c3cccc4[nH]nnc34)cc2c1 +c1ccc2[nH]c(-n3cnc4nc5nc[nH]c5nc43)cc2c1 +c1cnc(-c2ccc(-c3cc4cc5occc5cc4o3)cc2)cn1 +c1cnc(-c2ccc(-c3ccc4[nH]c5ccncc5c4c3)cc2)cn1 +c1cnc(-c2ccc(-n3cnc4nc5nc[nH]c5nc43)cc2)cn1 +c1cnc2c(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3ccncc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3cnccc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccnc2c1 +c1cnc2c(-c3ccc4c5ccccc5c5[nH]cnc5c4c3)ccnc2c1 +c1cnc2c(-c3ccc4ccsc4c3)ccnc2c1 +c1cnc2c(-c3ccc4cc[nH]c4c3)ccnc2c1 +c1cnc2c(-c3ccc4sccc4c3)ccnc2c1 +c1cnc2c(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccnc2c1 +c1cnc2c(-c3ccc4[nH]nnc4c3)ccnc2c1 +c1cnc2c(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)ccnc2c1 +c1cnc2c(-c3cccc4c3[nH]c3cnccc34)ccnc2c1 +c1cnc2c(-c3cccc4c5ccccc5c5nccnc5c34)ccnc2c1 +c1cnc2c(-c3cccc4ncoc34)ccnc2c1 +c1cnc2c(-c3cnc4oc5ccccc5c4c3)ccnc2c1 +c1cnc2c(-c3cncc4c3[nH]c3ccccc34)ccnc2c1 +c1cnc2c(-n3c4ccncc4c4cnccc43)ccnc2c1 +c1cnc2c(c1)cc(-c1c3ncoc3cc3ncoc13)c1cccnc12 +c1cnc2c(c1)cc(-c1c3[nH]ccc3cc3ccoc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cc3nc4ccoc4nc3[nH]1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3c4ccccc4c4nc[nH]c4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3oc4ccccc4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3ocnc3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3sccc3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3[nH]c4[nH]c5ccccc5c4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3c1cnc1ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3c4nccnc4c4ccccc4c13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3ocnc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3[nH]c4[nH]c5ccccc5c4c13)c1cccnc12 +c1cnc2c(c1)cc(-c1cncc3c1[nH]c1ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1nc3ccccc3c3ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1nc3ccccc3s1)c1cccnc12 +c1cnc2c(c1)cc(-n1c3ccccc3c3c4[nH]c5ccccc5c4ccc31)c1cccnc12 +c1cnc2c(c1)cc(-n1nnc3ccccc31)c1cccnc12 +c1cnc2c(c1)ccc1c(-c3cc4cc5occc5cc4o3)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(cnc5ccccc54)c3)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4cnc5ccccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4ncoc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4oc5ncccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4sc5ncccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]c5ccncc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]ccc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccnnc3)ccnc12 +c1cnc2c(c1)ccc1c(-c3cncc4c3[nH]c3ccncc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3nc4cc5ocnc5cc4o3)ccnc12 +c1cnc2c(c1)ccc1c(-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)ccnc12 +c1cnc2c(c1)ccc1cc(-c3c4ncsc4cc4ncsc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3c4[nH]ccc4cc4ccoc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c5c3CCCN5CCC4)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c5ccccc5c5nccnc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4ncsc4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4sccc4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4[nH]c5ccncc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3cccc4[nH]c5ccncc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cccc4[nH]c5cnccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccnc4sc5ccccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cnc4sc5ncccc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3c[nH]c4ccccc34)cnc12 +c1cnc2c(c1)ccc1cc(-n3ccc4ccccc43)cnc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4cnc5ccccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4ocnc4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4sc5ncccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4[nH]c5cnccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4c3[nH]c3ccncc34)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4nn[nH]c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccnc4sc5ncccc5c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3coc4ccccc34)nc12 +c1cnc2c(c1)ccc1ccc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)nc12 +c1cnc2c(c1)ccc1ccc(-c3nc4ccccc4o3)nc12 +c1cnc2c(c1)ccc1ccc(-n3ccc4cc5ccoc5cc43)nc12 +c1cnc2c(c1)ccc1ccc(-n3ccc4ccccc43)nc12 +c1cnc2c(c1)ccc1ccc(-n3nnc4ccccc43)nc12 +c1cnc2cc(-c3c4ncoc4cc4ncoc34)ccc2n1 +c1cnc2cc(-c3c4ncoc4cc4ncoc34)cnc2c1 +c1cnc2cc(-c3c4[nH]ccc4cc4ccoc34)ccc2n1 +c1cnc2cc(-c3cc4cc5ccoc5cc4[nH]3)ccc2n1 +c1cnc2cc(-c3cc4nc5ccoc5nc4[nH]3)cnc2c1 +c1cnc2cc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)cnc2c1 +c1cnc2cc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)cnc2c1 +c1cnc2cc(-c3ccc4occc4c3)cnc2c1 +c1cnc2cc(-c3ccc4ocnc4c3)ccc2n1 +c1cnc2cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cnc2c1 +c1cnc2cc(-c3cccc4ncoc34)cnc2c1 +c1cnc2cc(-c3cncc4[nH]c5ccccc5c34)cnc2c1 +c1cnc2cc(-c3coc4nc5[nH]ccc5nc34)ccc2n1 +c1cnc2cc(-c3coc4nc5[nH]ccc5nc34)cnc2c1 +c1cnc2cc(-c3nc4ccccc4s3)cnc2c1 +c1cnc2cc(-c3nccc4[nH]c5ccccc5c34)cnc2c1 +c1cnc2cc(-n3ccc4nc5ccoc5nc43)ccc2n1 +c1cnc2ccc(-c3c4ccoc4cc4ccoc34)nc2c1 +c1cnc2ccc(-c3c4cc[nH]c4cc4occc34)nc2c1 +c1cnc2ccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)nc2c1 +c1cnc2ccc(-c3ccc4nn[nH]c4c3)nc2c1 +c1cnc2ccc(-c3ccc4oc5ncccc5c4c3)nc2c1 +c1cnc2ccc(-c3ccc4scnc4c3)nc2c1 +c1cnc2ccc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)nc2c1 +c1cnc2ccc(-c3ccc4[nH]ccc4c3)nc2c1 +c1cnc2ccc(-c3cccc4oc5ccccc5c34)nc2c1 +c1cnc2ccc(-c3cccc4ocnc34)nc2c1 +c1cnc2ccc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)nc2c1 +c1cnc2ccc(-c3ccnnc3)nc2c1 +c1cnc2ccc(-c3cncc4c3[nH]c3ccncc34)nc2c1 +c1cnc2ccc(-c3coc4nc5[nH]ccc5nc34)nc2c1 +c1cnc2ccc(-c3c[nH]c4cc5occc5cc34)nc2c1 +c1cnc2ccc(-c3nc4ccccc4s3)nc2c1 +c1cnc2ccc(-n3c4ccccc4c4cnccc43)nc2c1 +c1cnc2nc(-c3c4cc[nH]c4cc4occc34)cnc2n1 +c1cnc2nc(-c3cc4cc5ccoc5cc4[nH]3)cnc2n1 +c1cnc2nc(-c3cc4nc5ccoc5nc4[nH]3)cnc2n1 +c1cnc2nc(-c3ccc4c(n3)sc3ncccc34)ccc2c1 +c1cnc2nc(-c3ccc4ncc5ccccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4ncsc4c3)cnc2n1 +c1cnc2nc(-c3ccc4oc5ccccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4oc5ncccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4[nH]ccc4c3)ccc2c1 +c1cnc2nc(-c3cccc4c3oc3ncccc34)ccc2c1 +c1cnc2nc(-c3cccc4c3sc3ncccc34)ccc2c1 +c1cnc2nc(-c3cccc4c5ccccc5c5[nH]cnc5c34)ccc2c1 +c1cnc2nc(-c3cccc4cnc5ccccc5c34)ccc2c1 +c1cnc2nc(-c3cccc4oc5ncccc5c34)ccc2c1 +c1cnc2nc(-c3cccc4ocnc34)ccc2c1 +c1cnc2nc(-c3cc[nH]n3)cnc2n1 +c1cnc2nc(-c3cncc4[nH]c5ccccc5c34)ccc2c1 +c1cnc2nc(-c3c[nH]c4nc5occc5nc34)cnc2n1 +c1cnc2nc(-n3c4ccccc4c4c5ccccc5[nH]c43)ccc2c1 +c1cnc2nc(-n3c4ccccc4c4ccncc43)ccc2c1 +c1cnc2ncc(-c3c4ccoc4cc4ccoc34)cc2c1 +c1cnc2ncc(-c3cc4nc5cc[nH]c5nc4o3)cc2c1 +c1cnc2ncc(-c3cc4[nH]c5ccccc5c4cn3)cc2c1 +c1cnc2ncc(-c3ccc4c(c3)[nH]c3cnccc34)cc2c1 +c1cnc2ncc(-c3ccc4c(n3)sc3ccccc34)cc2c1 +c1cnc2ncc(-c3ccc4[nH]c5ccncc5c4c3)cc2c1 +c1cnc2ncc(-c3ccc4[nH]c5cnccc5c4c3)cc2c1 +c1cnc2ncc(-c3cccc4c3cnc3ccccc34)cc2c1 +c1cnc2ncc(-c3cccc4c3[nH]c3cnccc34)cc2c1 +c1cnc2ncc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)cc2c1 +c1cnc2ncc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cc2c1 +c1cnc2ncc(-c3cccc4scnc34)cc2c1 +c1cnc2ncc(-c3cc[nH]n3)cc2c1 +c1cnc2ncc(-c3cncc4c3[nH]c3ccccc34)cc2c1 +c1cnc2ncc(-c3coc4nc5[nH]ccc5nc34)cc2c1 +c1cnc2ncc(-c3nc4ccccc4s3)cc2c1 +c1cnc2ncc(-c3nccc4[nH]c5ccccc5c34)cc2c1 +c1cnc2ncc(-n3cnc4c5ccccc5c5ccccc5c43)cc2c1 +c1cnc2nccc(-c3cc4[nH]c5ccncc5c4cn3)c2c1 +c1cnc2nccc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)c2c1 +c1cnc2nccc(-c3ccc4c5ccccc5c5nccnc5c4c3)c2c1 +c1cnc2nccc(-c3ccc4ccsc4c3)c2c1 +c1cnc2nccc(-c3ccc4occc4c3)c2c1 +c1cnc2nccc(-c3ccc4sc5ncccc5c4c3)c2c1 +c1cnc2nccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)c2c1 +c1cnc2nccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c2c1 +c1cnc2nccc(-n3c4ccccc4c4ccncc43)c2c1 +c1cnc2nccc(-n3ccc4cc5ccoc5cc43)c2c1 +c1cnc2nccc(-n3cnc4c5ccccc5c5ccccc5c43)c2c1 +c1cnc2oc3c(-c4c5[nH]cnc5cc5nc[nH]c45)cccc3c2c1 +c1cnc2oc3c(-c4ccc5ncoc5c4)cccc3c2c1 +c1cnc2oc3c(-c4cnc5nccnc5n4)cccc3c2c1 +c1cnc2oc3c(-c4cncc5c4[nH]c4ccncc45)cccc3c2c1 +c1cnc2oc3c(-c4ncon4)cccc3c2c1 +c1cnc2oc3cc(-c4c5[nH]cnc5cc5nc[nH]c45)ccc3c2c1 +c1cnc2oc3cc(-c4cc5nc6cc[nH]c6nc5o4)ccc3c2c1 +c1cnc2oc3cc(-c4ccc5ncoc5c4)ccc3c2c1 +c1cnc2oc3cc(-c4cccc5c4[nH]c4cnccc45)ccc3c2c1 +c1cnc2oc3cc(-c4c[nH]c5ccncc45)ccc3c2c1 +c1cnc2oc3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c2c1 +c1cnc2oc3ccc(-c4c5[nH]cnc5nc5nc[nH]c45)cc3c2c1 +c1cnc2oc3ccc(-c4cc5cnccc5[nH]4)cc3c2c1 +c1cnc2oc3ccc(-c4cc5nc6cc[nH]c6nc5o4)cc3c2c1 +c1cnc2oc3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c2c1 +c1cnc2oc3ccc(-c4ccc5c(c4)[nH]c4cnccc45)cc3c2c1 +c1cnc2oc3ccc(-c4ccc5sccc5c4)cc3c2c1 +c1cnc2oc3ccc(-c4c[nH]c5ccncc45)cc3c2c1 +c1cnc2oc3ccc(-c4nc5cc6nc[nH]c6cc5[nH]4)cc3c2c1 +c1cnc2sc3c(-c4c5[nH]cnc5nc5nc[nH]c45)cccc3c2c1 +c1cnc2sc3c(-c4cncs4)cccc3c2c1 +c1cnc2sc3c(-c4nc5cc6nc[nH]c6cc5[nH]4)cccc3c2c1 +c1cnc2sc3c(-c4nc5nc6ocnc6nc5o4)cccc3c2c1 +c1cnc2sc3c(-c4nccs4)cccc3c2c1 +c1cnc2sc3c(-c4ncon4)cccc3c2c1 +c1cnc2sc3c(-n4cnc5nc6nc[nH]c6cc54)cccc3c2c1 +c1cnc2sc3cc(-c4c5nc[nH]c5cc5[nH]cnc45)ccc3c2c1 +c1cnc2sc3cc(-c4cc5cnccc5[nH]4)ccc3c2c1 +c1cnc2sc3cc(-c4coc5cc6ccoc6cc45)ccc3c2c1 +c1cnc2sc3cc(-c4c[nH]c5nc6occc6nc45)ccc3c2c1 +c1cnc2sc3cc(-c4ncno4)ccc3c2c1 +c1cnc2sc3cc(-n4c5ccccc5c5ccncc54)ccc3c2c1 +c1cnc2sc3ccc(-c4c5nc[nH]c5cc5[nH]cnc45)cc3c2c1 +c1cnc2sc3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c2c1 +c1cnc2sc3ccc(-c4ccc(-c5cnccn5)cc4)cc3c2c1 +c1cnc2sc3ccc(-c4nc5nc6ocnc6nc5o4)cc3c2c1 +c1cnc2sc3ccc(-c4nccc5[nH]c6ccncc6c45)cc3c2c1 +c1cnc2sc3ccc(-n4cnc5nc6nc[nH]c6cc54)cc3c2c1 +c1cnc2sc3nc(-c4c5[nH]cnc5nc5nc[nH]c45)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5nn[nH]c5c4)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5ocnc5c4)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5[nH]nnc5c4)ccc3c2c1 +c1cnc2sc3nc(-c4cnoc4)ccc3c2c1 +c1cnc2sc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)ccc3c2c1 +c1cnc2sc3nc(-c4nccc5[nH]ccc45)ccc3c2c1 +c1cnc2sc3ncc(-c4cc5nc6ccoc6nc5[nH]4)cc3c2c1 +c1cnc2sc3ncc(-c4cscn4)cc3c2c1 +c1cnc2sc3ncc(-c4c[nH]c5nc6occc6nc45)cc3c2c1 +c1cnc2sc3ncc(-n4c5ccccc5c5ccncc54)cc3c2c1 +c1cnc2sc3ncc(-n4c5ccncc5c5cnccc54)cc3c2c1 +c1cnc2sc3ncc(-n4cnc5nc6nc[nH]c6nc54)cc3c2c1 +c1cnc2sc3nccc(-c4cc5cnccc5[nH]4)c3c2c1 +c1cnc2sc3nccc(-c4ccc5ncoc5c4)c3c2c1 +c1cnc2sc3nccc(-c4ccc5ocnc5c4)c3c2c1 +c1cnc2sc3nccc(-c4ccon4)c3c2c1 +c1cnc2sc3nccc(-c4cnc5nccnc5n4)c3c2c1 +c1cnc2sc3nccc(-c4nc5nc6nc[nH]c6cc5[nH]4)c3c2c1 +c1cnc2sc3nccc(-n4c5ccccc5c5ccncc54)c3c2c1 +c1cnc2[nH]c3c(-c4c5cc[nH]c5cc5occc45)cccc3c2c1 +c1cnc2[nH]c3c(-c4cc5cc6ccoc6cc5[nH]4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5c(c4)c4ccccc4c4nccnc54)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5c6ccccc6c6nccnc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5oc6ncccc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5[nH]c6ccncc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4c[nH]c5nc6occc6nc45)cccc3c2c1 +c1cnc2[nH]c3c(-c4nc5cc6ocnc6cc5o4)cccc3c2c1 +c1cnc2[nH]c3c(-c4nc5nc6nc[nH]c6nc5[nH]4)cccc3c2c1 +c1cnc2[nH]c3c(-c4nccc5[nH]c6ccncc6c45)cccc3c2c1 +c1cnc2[nH]c3cc(-c4c5ncoc5cc5ncoc45)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5c(n4)sc4ncccc45)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5c6ccccc6c6nc[nH]c6c5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5occc5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5[nH]c6ccncc6c5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4nc5c6ccccc6c6ccccc6c5[nH]4)ccc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5c(c4)oc4ncccc45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5c6ccccc6c6nccnc6c5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5ccoc5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5oc6ncccc6c5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4cccc5c6ccccc6c6[nH]cnc6c45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccnc5sc6ncccc6c45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccnnc4)cc3c2c1 +c1cnc2[nH]c3ccc(-n4c5ccccc5c5cnccc54)cc3c2c1 +c1cnc2[nH]c3ccc(-n4cnc5nc6nc[nH]c6nc54)cc3c2c1 +c1cnn(-c2ccc(-c3cnccn3)cc2)c1 +c1cnn(-c2ccc3[nH]nnc3c2)c1 +c1cnn(-c2cscn2)c1 +c1cnn(-c2c[nH]c3nc4occc4nc23)c1 +c1cnn(-n2cnc3nc4nc[nH]c4nc32)c1 +c1cnnc(-c2cc3cccnc3c3ncccc23)c1 +c1cnnc(-c2ccc(-c3cnccn3)cc2)c1 +c1cnnc(-c2ccc3c(c2)[nH]c2ncccc23)c1 +c1cnnc(-c2ccc3c(cnc4ccccc43)c2)c1 +c1cnnc(-c2ccc3sc4ccccc4c3c2)c1 +c1cnnc(-c2ccc3[nH]c4cnccc4c3c2)c1 +c1cnnc(-c2cccc3cnc4ccccc4c23)c1 +c1cnnc(-c2ccnc3c2ccc2cccnc23)c1 +c1cnnc(-c2ccnc3cccnc23)c1 +c1cnnc(-c2cnc3[nH]c4ccccc4c3c2)c1 +c1cnnc(-c2cncc3cc[nH]c23)c1 +c1cnnc(-c2cnoc2)c1 +c1cnnc(-c2cscn2)c1 +c1cnnc(-c2nccs2)c1 +c1cnnc(-n2nnc3ccccc32)c1 +c1csc(-c2c3ncsc3cc3ncsc23)n1 +c1csc(-c2cc3nc4ccoc4nc3[nH]2)n1 +c1csc(-c2ccc3ccsc3c2)n1 +c1csc(-c2cn[nH]c2)n1 +c1csc(-c2coc3cc4[nH]ccc4cc23)n1 +c1csc(-c2c[nH]c3nc4occc4nc23)n1 +c1nc(-c2ccc3sccc3c2)cs1 +c1nc(-n2ccc3nc4ccoc4nc32)no1 +c1nc2c(-c3c4ncsc4cc4ncsc34)c3nc[nH]c3cc2[nH]1 +c1nc2c(-c3ccc4c5c3CCCN5CCC4)c3nc[nH]c3cc2[nH]1 +c1nc2c(-c3ccc4ncsc4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4nn[nH]c4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4scnc4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4[nH]nnc4c3)c3scnc3cc2s1 +c1nc2c(-c3nc4nc5nc[nH]c5nc4[nH]3)c3nc[nH]c3cc2[nH]1 +c1nc2c(-n3ccc4nc5ccoc5nc43)c3nc[nH]c3cc2[nH]1 +c1nc2cc(-c3ccc4ncsc4c3)ccc2o1 +c1nc2cc(-c3ccc4nn[nH]c4c3)ccc2o1 +c1nc2cc(-c3ccc4ocnc4c3)ccc2o1 +c1nc2cc(-c3cnoc3)ccc2s1 +c1nc2cc(-c3cscn3)ccc2o1 +c1nc2cc3nc(-c4cc5nc6ccoc6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2cc3nc(-c4ccc5ccsc5c4)[nH]c3cc2[nH]1 +c1nc2cc3nc(-c4ccc5scnc5c4)oc3nc2o1 +c1nc2cc3nc(-c4ccc5[nH]nnc5c4)oc3nc2o1 +c1nc2cc3nc(-c4c[nH]c5nc6occc6nc45)[nH]c3cc2[nH]1 +c1nc2cc3ncn(-c4c5cc[nH]c5cc5occc45)c3cc2[nH]1 +c1nc2cc3ncn(-c4cc5c6c(c4)CCCN6CCC5)c3cc2[nH]1 +c1nc2cc3ncn(-c4ccc5ccsc5c4)c3cc2[nH]1 +c1nc2cc3ncn(-c4ccc5scnc5c4)c3cc2[nH]1 +c1nc2cc3oc(-c4ccc5nn[nH]c5c4)nc3cc2o1 +c1nc2cc3oc(-c4cnoc4)nc3cc2o1 +c1nc2ccc(-c3c4ncoc4nc4ocnc34)cc2o1 +c1nc2ccc(-c3c4ncsc4cc4ncsc34)cc2o1 +c1nc2ccc(-c3cnoc3)cc2o1 +c1nc2ccc(-c3c[nH]c4nc5occc5nc34)cc2o1 +c1nc2ccc(-c3nc4nc5ocnc5nc4o3)cc2o1 +c1nc2nc3nc(-c4c5ncsc5cc5ncsc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4c5[nH]ccc5cc5ccoc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4cc5nc6ccoc6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4ccc5scnc5c4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4c[nH]c5nc6occc6nc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5cc6ncoc6nc5o4)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5nc6ocnc6nc5o4)[nH]c3nc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]ccc5cc5ccoc45)c3cc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]ccc5cc5ccoc45)c3nc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]cnc5nc5nc[nH]c45)c3nc2[nH]1 +c1nc2nc3ncn(-c4cc5nc6ccoc6nc5[nH]4)c3cc2[nH]1 +c1nc2nc3ncn(-c4ccc(-c5cc6c7c(c5)CCCN7CCC6)cc4)c3nc2[nH]1 +c1nc2nc3ncn(-c4ccc5ncoc5c4)c3nc2[nH]1 +c1nc2nc3ncn(-c4ncon4)c3nc2[nH]1 +c1nc2nc3nc[nH]c3c(-c3c4ncoc4cc4ncoc34)c2[nH]1 +c1nc2nc3nc[nH]c3c(-c3ccc4ocnc4c3)c2[nH]1 +c1nc2nc3nc[nH]c3c(-c3c[nH]c4cc5occc5cc34)c2[nH]1 +c1nc2nc3oc(-c4c5ncsc5cc5ncsc45)nc3nc2o1 +c1nc2nc3oc(-c4ccc(-c5cc6c7c(c5)CCCN7CCC6)cc4)nc3nc2o1 +c1nc2nc3oc(-c4ccc5scnc5c4)nc3nc2o1 +c1ncc(-c2ccc3[nH]nnc3c2)s1 +c1noc(-c2c3ncsc3cc3ncsc23)n1 +c1noc(-c2cc3c4c(c2)CCCN4CCC3)n1 +c1noc(-c2ccc3ocnc3c2)n1 +c1noc(-c2coc3cc4ccoc4cc23)n1 +c1noc(-c2nc3cc4ocnc4cc3o2)n1 +c1noc(-c2nc3nc4nc[nH]c4nc3[nH]2)n1 +c1nocc1-c1ccc2c3c1CCCN3CCC2 +CC(=O)c1ccc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +CC(=O)c1ccc(-c2cc(C)c3[nH]c4c(C)cccc4c3c2)cc1 +CC(=O)c1ccc(-c2cc(N(C)C)c3ccccc3c2)cc1 +CC(=O)c1ccc(-c2cc3c4c(c2)CCCN4CCC3)cc1 +CC(=O)c1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)cc1 +CC(=O)c1ccc(-c2cc3cc4cc[nH]c4cc3o2)cc1 +CC(=O)c1ccc(-c2cc3ccccc3[nH]2)cc1 +CC(=O)c1ccc(cc1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +CC(=O)c1ccc(cc1)c1cc2c(Sc3c(cccc3)N2)cc1 +CC(=O)c1ccc(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +CC(=O)c1ccc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)Oc2ccccc2N3C)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cc1 +CC(=O)c1ccc(-c2ccc3c(n2)sc2ccccc23)cc1 +CC(=O)c1ccc(-c2ccc3c4c(C)c(C)c(C)cc4n(C)c3c2)cc1 +CC(=O)c1ccc(-c2ccc3oc4ncccc4c3c2)cc1 +CC(=O)c1ccc(-c2ccc3[nH]c4ccc5c6ccccc6[nH]c5c4c3c2)cc1 +CC(=O)c1ccc(-c2cccc(N)c2)cc1 +CC(=O)c1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)cc1 +CC(=O)c1ccc(-c2cccc3c2-c2ccccc2C3(C)C)cc1 +CC(=O)c1ccc(cc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +CC(=O)c1ccc(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +CC(=O)c1ccc(-c2cccc3c2ncc2ccccc23)cc1 +CC(=O)c1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +CC(=O)c1ccc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +CC(=O)c1ccc(-c2cccc3oc4ccccc4c23)cc1 +CC(=O)c1ccc(-c2cccc3oc4ncccc4c23)cc1 +CC(=O)c1ccc(-c2cccc3occc23)cc1 +CC(=O)c1ccc(-c2cccc3scnc23)cc1 +CC(=O)c1ccc(-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)cc1 +CC(=O)c1ccc(-c2cccc3[nH]c4ccncc4c23)cc1 +CC(=O)c1ccc(-c2cc[nH]n2)cc1 +CC(=O)c1ccc(-c2coc3nc4[nH]ccc4nc23)cc1 +CC(=O)c1ccc(-c2nc3cc4scnc4cc3s2)cc1 +CC(=O)c1ccc(-c2nc3ccccc3o2)cc1 +CC(=O)c1ccc(-c2nccc3c2[nH]c2ccccc23)cc1 +CC(=O)c1ccc(-n2c3ccccc3c(=O)c3ccccc32)cc1 +CC(=O)c1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)cc1 +CC(=O)c1ccc(-n2c3ccccc3c3ccncc32)cc1 +CC(=O)c1ccc(-n2cnc3c4ccccc4c4ccccc4c32)cc1 +CC(=O)c1ccc(-n2nnc3ccccc32)cc1 +CC(=O)c1cccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +CC(=O)c1cccc(-c2c(C)c(C)c(C)c3c4ccccc4n(C)c23)c1 +CC(=O)c1cccc(c1)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +CC(=O)c1cccc(c1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +CC(=O)c1cccc(-c2cc3ccccc3cc2N(C)C)c1 +CC(=O)c1cccc(-c2cc3ccccc3o2)c1 +CC(=O)c1cccc(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +CC(=O)c1cccc(c1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +CC(=O)c1cccc(-c2ccc3c(n2)sc2ccccc23)c1 +CC(=O)c1cccc(c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +CC(=O)c1cccc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)c1 +CC(=O)c1cccc(-c2ccc3cc(N(C)C)ccc3c2)c1 +CC(=O)c1cccc(-c2ccc3occc3c2)c1 +CC(=O)c1cccc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c1 +CC(=O)c1cccc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c1 +CC(=O)c1cccc(c1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +CC(=O)c1cccc(c1)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +CC(=O)c1cccc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +CC(=O)c1cccc(-c2cccc3c2oc2ncccc23)c1 +CC(=O)c1cccc(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)c1 +CC(=O)c1cccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c1 +CC(=O)c1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +CC(=O)c1cccc(-c2cccc3ocnc23)c1 +CC(=O)c1cccc(-c2cccc3scnc23)c1 +CC(=O)c1cccc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c1 +CC(=O)c1cccc(-c2ccnc3sc4ncccc4c23)c1 +CC(=O)c1cccc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +CC(=O)c1cccc(-c2coc3cc4ccoc4cc23)c1 +CC(=O)c1cccc(-c2c[nH]c3ccccc23)c1 +CC(=O)c1ccccc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +CC(=O)c1ccccc1-c1c2ncsc2cc2ncsc12 +CC(=O)c1ccccc1-c1cc(C)c2[nH]c3c(C)cccc3c2c1 +CC(=O)c1ccccc1-c1cc2cc3cc[nH]c3cc2o1 +CC(=O)c1ccccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +CC(=O)c1ccccc1c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +CC(=O)c1ccccc1c1ccc2CCc3c(cccc3)Nc2c1 +CC(=O)c1ccccc1-c1ccc2c(c1)c1ccccc1c1nc[nH]c21 +CC(=O)c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12 +CC(=O)c1ccccc1-c1ccc2cc(N(C)C)ccc2c1 +CC(=O)c1ccccc1-c1ccc2oc3ccccc3c2c1 +CC(=O)c1ccccc1-c1ccc2oc3ncccc3c2c1 +CC(=O)c1ccccc1-c1ccc2[nH]c3ccccc3c(=O)c2c1 +CC(=O)c1ccccc1-c1ccc2[nH]c3cnccc3c2c1 +CC(=O)c1ccccc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +CC(=O)c1ccccc1-c1cccc2c1oc1ncccc12 +CC(=O)c1ccccc1-c1cccc2c1sc1ncccc12 +CC(=O)c1ccccc1-c1cccc2c3c(C)c(C)c(C)cc3n(C)c12 +CC(=O)c1ccccc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +CC(=O)c1ccccc1-c1cccc2cc(N(C)C)ccc12 +CC(=O)c1ccccc1-c1cccc2oc3ncccc3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3ccc4c5ccccc5[nH]c4c3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3cnccc3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3[nH]c4ccccc4c3c12 +CC(=O)c1ccccc1-c1cccnn1 +CC(=O)c1ccccc1-c1cncc2c1[nH]c1ccccc12 +CC(=O)c1ccccc1-c1cncc2c1[nH]c1ccncc12 +CC(=O)c1ccccc1-n1c2ccccc2c2ccncc21 +CC(=O)c1ccccc1-n1c2ccccc2c2cnccc21 +CC(=O)c1ccccc1-n1nnc2ccccc21 +Cc1(-c2c3ccoc3cc3ccoc23)-c2ccccc2-c2ccccc2-1 +N#Cc1c(c(C#N)cc(c1)C1(C)c2c(cccc2)Nc2c1cccc2)C#N +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2C2(C)c3c(cccc3)Nc3c2cccc3)ccccc1 +c12c(sc(c1)C1(C)c3c(cccc3)Nc3c1cccc3)cccc2 +Cc1(-c2cc3ccccc3[nH]2)-c2ccccc2-c2ccccc2-1 +N#Cc1ccc(c(C#N)c1)C1(C)c2c(cccc2)Nc2c1cccc2 +O=c1c2c(cc(cc2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +CC1(c2c(-c3c1cccc3)cccc2)c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1c2c(C(=O)N1)ccc(c2)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2ccc3c4c2CCCN4CCC3)-c2ccccc2-c2ccccc2-1 +c12c(b3c4c(oc5c3c(o1)c(cc5)C1(C)c3c(cccc3)Nc3c1cccc3)cccc4)cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)C1(C)c2c(cccc2)Nc2c1cccc2 +c12c(nn[nH]2)ccc(c1)C1(C)c2c(cccc2)Nc2c1cccc2 +n1c2c(oc1)ccc(c2)C1(C)c2c(cccc2)Nc2c1cccc2 +O=c1c2c(ccc(c2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +Cc1(-c2ccc3[nH]ccc(=O)c3c2)-c2ccccc2-c2ccccc2-1 +c12c(nn[nH]2)cc(cc1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c(=O)c4ccccc4[nH]c23)-c2ccccc2-c2ccccc2-1 +O=C1c2c(C(=O)N1)cccc2C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cccc3c2sc2ncccc23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c2[nH]c2cnccc23)-c2ccccc2-c2ccccc2-1 +c12c(c(ccc2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]c2ncccc12 +Cc1(-c2cccc3c4ccccc4c4nc[nH]c4c23)-c2ccccc2-c2ccccc2-1 +c12c(scc1)c(ccc2)C1(C)c2c(cccc2)Nc2c1cccc2 +c12c(cccc2C2(C)c3c(cccc3)Nc3c2cccc3)cnc2c1cccc2 +Cc1(-c2cccc3nn[nH]c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3oc4ncccc4c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3occc23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccnn2)-c2ccccc2-c2ccccc2-1 +c1(c2ncc(nc2)C2(C)c3c(cccc3)Nc3c2cccc3)ccccc1 +n1c2c(ccc1)ccc1c2ncc(c1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cnc3c4ccccc4c4ccccc4c3n2)-c2ccccc2-c2ccccc2-1 +c12c(c3c(c(cnc3)C3(C)c4c(cccc4)Nc4c3cccc4)[nH]2)cncc1 +Cc1(-c2c[nH]c3ccccc23)-c2ccccc2-c2ccccc2-1 +n1c2nc3nc(C4(C)c5c(cccc5)Nc5c4cccc5)[nH]c3nc2[nH]c1 +n1c2nc3oc(nc3nc2oc1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2nccc3c2[nH]c2ccccc23)-c2ccccc2-c2ccccc2-1 +c12c(ccnc2C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +n1ccsc1C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-n2c3ccccc3c3cnccc32)-c2ccccc2-c2ccccc2-1 +O=C1c2c(C(=O)C(=C1)c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +O=c1c2c(cc(cc2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +O=C1c2c(C(=O)C=C1)ccc(c2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2c1ccnc2 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2ncccc12 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +n1c2c(oc1)cc(cc2)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(ccc(c2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]c2c1ccnc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(sc3c1cccc3c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(oc1)c(ccc2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)cccc1c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(nn[nH]2)c(ccc1)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(c2ncccc2c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ncccc1 +n1c2c(nccc2)c(cc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(ncc(c2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccc1 +c12c(c(cnc2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +c12c(c(cnc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]cc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1cc(sc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c(csc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=c1c2c(cccc2)[nH]cc1c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(ccnc2)[nH]cc1c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(c3c(n1c1cc4c(cc1)Nc1c5c6c(n(c7ccccc7)c5ccc1C4(C)C)cccc6)ccnc3)cncc2 +O=C1C=CC(=O)N1c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +n1c2c(c(c3c(nc[nH]3)c2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c1 +O=c1c2c(cc(cc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)cccc2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(cc(cc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)cnc2c1cccc2 +c12c(scc1)cc(cc2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +O=c1c2c(ccc(c2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(c(ccc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2ncccc12 +c12c(cccc2)cnc2c1c(ccc2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(cccc2c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2c1ccnc2 +c12c(cccc2c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2ncccc12 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +n1occ(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(n(c3c1ccnc3)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)cccc2 +c12c(n(cc1)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)ccnc2 +n1c2nc3nc[nH]c3cc2n(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +O=C1C=C(C(=O)N1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ccccc1 +c1(c2ncc(cc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ncccc1 +c1(c2nccnc2)ccc(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(cc(cc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12nccnc1ccc(c2)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(c(ccc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +c12c(sc3c1c(ccc3)c1c3c(ccc1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +n1c2ncccc2c(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(ccc1)ccc1c2ncc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2ncc(nc2ncc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c(csc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(nc3c(nc(o3)c3c4c(ccc3)Nc3c(C4(C)C)cc4n(c5ccccc5)c5c(c4c3)cccc5)c2)oc1 +c1(C#N)cnc(nc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1cccc(C#N)c1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(c(c3c(nc[nH]3)c2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c1 +c12nc3c(oc(c3)c3ccc4c(c3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)nc1[nH]cc2 +N#Cc1c(c(C#N)c(cc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3)C#N +N#Cc1ccc(c(C#N)c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +c12c(cc(cc2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +c12c(cccc2)[nH]c2nc(ccc12)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2nc(ccc2ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(ccc(c2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)ccc(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(nn[nH]2)cc(cc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1c(C#N)c(ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +c12c(nn[nH]2)c(ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1ccccc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2ncccc2c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ncccc1 +c1(c2nccc(c2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(nccc2)c(cc1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2nc(cnc2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ccccc1 +c12c(c(cnc2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +n1cc(sc1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1cc(sc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(cccc2)c(nc2c1cccc2)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2nc3nc(c4ccc5c(c4)Nc4c6c7c(n(c8ccccc8)c6ccc4C5(C)C)cccc7)[nH]c3cc2[nH]c1 +n1c2nc3nc(c4ccc5c(c4)Nc4c(C5(C)C)cc5n(c6ccccc6)c6c(c5c4)cccc6)[nH]c3nc2[nH]c1 +c12c(ccnc2c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +n1ccsc1c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1cnoc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)C(=C1)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(nc3c(nco3)c2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)oc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +N#Cc1c(c(C#N)cc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4)C#N +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1c3c(ccc1)Nc1c5c6c(n(c7ccccc7)c5ccc1C3(C)C)cccc6)cccc4)cccc2 +c12c(cc(nc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +N#Cc1ccc(cc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cc(cc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]c2ncccc12 +n1c2c(nc(cc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccc1 +O=C(c1cccc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(sc3c1cccc3c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +c12c(scc1)c(ccc2)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)cccc1c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=c1c2c(cccc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +N#Cc1ccccc1c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cccc2)[nH]c2nccc(c12)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1occ(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12nc3c(occ3c3c4c(ccc3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)nc1[nH]cc2 +c12c(scc1c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c(csc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12nc3c(occ3)nc1[nH]cc2c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(nc3c(nc(o3)c3c4c(ccc3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)c2)oc1 +n1c2c(cc3c(nc(c4c5c(ccc4)Nc4c6c7c(n(c8ccccc8)c6ccc4C5(C)C)cccc7)[nH]3)c2)[nH]c1 +c1(C#N)cnc(nc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2nccnc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +c12c(n(c3ncccc13)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)cc2)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ccccc1 +O=c1c2c(cccc2)[nH]c(c1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +N#Cc1c(c(C#N)c(cc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1)C#N +N#Cc1ccc(cc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(scc1)cc(cc2)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(nn[nH]2)ccc(c1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(sc3c1cc(cc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +O=c1c2c(ccc(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c12c(cccc2c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)cnc2c1cccc2 +c12c(nn[nH]2)cccc1c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(sc3c1c(ccc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +c1(c2nccnc2)ccccc1c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c1(c2nccc(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ncccc1 +c1(c2nc(cnc2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ccccc1 +c12c(c3c(c(cnc3)c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)[nH]2)cncc1 +c12nc3c(occ3c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)nc1[nH]cc2 +n1c2nc3oc(nc3nc2oc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(n(cc1)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)ccnc2 +CC1(c2c(-c3c1cccc3)cccc2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +O=C1c2c(C(=O)C(=C1)N1c3c(C(c4c1cccc4)(C)C)cc1n(c4ccccc4)c4c(c1c3)cccc4)cccc2 +O=C1c2c(C(=O)C(=C1)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +O=C1c2c(C(=O)N1N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +O=C1C=CC(=O)N1N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +O=C1C=CC(=O)N1N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2c(nc3c(nco3)c2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)oc1 +n1c2c(cc3c(nc[nH]3)c2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)ccccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)N2c3c(C(C)(c4c2cccc4)C)cccc3)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)N1c3c(C(c5c1cccc5)(C)C)cc1n(c5ccccc5)c5c(c1c3)cccc5)cccc4)cccc2 +n1c2c(ccc1)cc(c1c2nccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2nccnc2)ccc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +N#Cc1c(C#N)cc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +N#Cc1c(c(C#N)c(cc1)N1c2c(C(C)(c3c1cccc3)C)cccc2)C#N +N#Cc1ccc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +O=c1c2c(cc(cc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(cccc2)cnc2c1ccc(c2)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(cccc2)cnc2c1ccc(c2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +c12c(sc3c1ccc(c3)N1c3c(C(c4c1cccc4)(C)C)cc1n(c4ccccc4)c4c(c1c3)cccc4)cccc2 +c12c(sc3c1ccc(c3)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +c12c(cc(cc2)N2c3c(C(C)(c4c2cccc4)C)cccc3)cnc2c1cccc2 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)N1c3c5c6c(n(c7ccccc7)c5ccc3C(c3c1cccc3)(C)C)cccc6)cccc4)cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cc(cc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cc(cc2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12nccnc1ccc(c2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(nn[nH]2)ccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(sc3c1cc(cc3)N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +c12c(ccc(c2)N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2c1ccnc2 +c12c(ccc(c2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]c2ncccc12 +c1(c2ncccc2)nc(ccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2ncccc2)nc(ccc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +N#Cc1cccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +O=c1c2c(c(ccc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(c(ccc2)N2c3c(C(C)(c4c2cccc4)C)cccc3)cnc2c1cccc2 +c12c(cccc2N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)cnc2c1cccc2 +c12nccnc1c(ccc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cccc2N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(cccc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2c1ccnc2 +c12c(cccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c2c1ccnc2 +c12c(cccc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2ncccc12 +c12c(cccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c2ncccc12 +O=c1c2c(cccc2N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(nn[nH]2)c(ccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2nccnc2)ccccc1N1c2c(C(C)(c3c1cccc3)C)cccc2 +N#Cc1ccccc1N1c2c(C(C)(c3c1cccc3)C)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2ncccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)ncccc1 +c1(c2nccc(c2)N2c3c(C(C)(c4c2cccc4)C)cccc3)ncccc1 +n1occc1N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +n1c2c(ccc1)ccc1c2ncc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +n1c2c(ccc1)ccc1c2ncc(c1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2ncc(cc2ccc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2ncc(nc2ncc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c1(c2nc(cnc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)ccccc1 +n1c(csc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(cccc2)[nH]c2c1ccnc2N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +n1cnoc1N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +O=c1c2c(n(cc1)N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +c12nc3c(occ3)nc1n(cc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +n1c2nc3nc[nH]c3nc2n(c1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +Fc1c(c(c(c(F)c1c1c2c(C(C)(c3c(cccc3)N2)C)ccc1)F)F)F +n1c2c(nc3c(nco3)c2c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)oc1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c1 +N#Cc1cc(cc(C#N)c1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)c2 +c12c(ccnc2)[nH]c(c1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(c3c(cc(nc3)c3c4c(C(C)(c5c(cccc5)N4)C)ccc3)[nH]2)cncc1 +c1(c2ncc(cc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ncccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(cc(cc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c2ncccc12 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(C(C)(c5c(cccc5)N3)C)ccc1)cccc4)cccc2 +c12c(scc1)ccc(c2)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(ccc(c2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c2ncccc12 +c12c(sc3c1c(ccc3)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +n1c2c(nccc2)c(cc1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c1(c2ncc(nc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ccccc1 +n1ccsc1c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(n(c3ncccc13)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3c4c(c5c6c(n(c7ccccc7)c5c3)cccc6)Nc3c(C4(C)C)cccc3)cc2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)c2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +N#Cc1ccc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(cc(cc2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)cnc2c1cccc2 +n1c2c(nc(cc2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ccc1 +c12c(scc1)ccc(c2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(nn[nH]2)cc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)cccc2 +O=c1c2c(cccc2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)[nH]cc1 +c1(c2nccc(c2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ncccc1 +n1c2c(nccc2)c(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1oc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12ncc(nc1cccc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c2ncc(cc2ccc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c(csc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c2nc3oc(nc3nc2oc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c1(c2nccnc2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ccccc1 +n1ccsc1c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +O=c1c2c(n(cc1)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)cccc2 +c12nc3c(occ3)nc1n(cc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +N#Cc1cc(C#N)cc(C#N)c1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3)F)F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)ccccc1 +c1(c2ncc(cc2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)ncccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3n(c5ccccc5)c5c(c3c3c(C(c6c(cccc6)N3)(C)C)c1)cccc5)cccc4)cccc2 +c12c(ccc(c2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)[nH]c2ncccc12 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(nn[nH]2)cccc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +n1c2ncccc2c(cc1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(ccnc2)[nH]cc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +n1ccsc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +CC1(c2c(-c3c1cccc3)cccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +O=C1c2c(C(=O)N1c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +O=c1c2c(cc(cc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)[nH]cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(c(ccc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)cnc2c1cccc2 +c12c(scc1)c(ccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(cccc2)cnc2c1c(ccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +n1c2c(oc1)cccc2c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(sc3c1c(ccc3)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +c12c(nn[nH]2)c(ccc1)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +n1c2c(ncc(c2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)ccc1 +c1(c2nc(cnc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)ccccc1 +c12c(occ1)cc1c(occ1c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)c2 +c12c(n(cc1)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)ccnc2 +CC1(c2c(-c3c1cccc3)cccc2)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +O=C1C=CC(=O)N1c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)[nH]c1 +N#Cc1c(c(C#N)c(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1)C#N +c12c(cccc2)cnc2c1ccc(c2)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(n(c5ccccc5)c5c3c3c(C(c6c(cccc6)N3)(C)C)cc5)ccc1)cccc4)cccc2 +n1c2c(nc(cc2)c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(oc1)cccc2c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(scc1)cccc2c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(nccc2)c(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1oc(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(ccc1)ccc1c2ncc(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(ncc(c2)c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)ccc1 +n1c2ncc(cc2ccc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1cc(sc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(occ1)cc1c(occ1c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)c2 +n1c2c(nc3c(nc(o3)c3c4c(n(c5ccccc5)c5c4c4c(C(c6c(cccc6)N4)(C)C)cc5)ccc3)c2)oc1 +c12c(n(c3c1ccnc3)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +n1c2c(n(c1)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(nnn1c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +Fc1c(c(c(c(F)c1c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3)F)F)F +c12c(cccc2)[nH]c2c1cc(nc2)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(occ1)cc1c(oc(c1)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)c2 +c12nc3c(oc(c3)c3ccc4n(c5ccccc5)c5c(c4c3)c3c(C(c4c(cccc4)N3)(C)C)cc5)nc1[nH]cc2 +c12c(cc(nc2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +N#Cc1ccc(c(C#N)c1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(ccc(c2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)cnc2c1cccc2 +c1(c2ncccc2)nc(ccc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(c(ccc2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]c2ncccc12 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1oc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2ncc(nc2ncc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12nc3c(occ3)nc1[nH]cc2c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(cc3c(nc(c4ccc5n(c6ccccc6)c6c(c5c4)c4c(C(c5c(cccc5)N4)(C)C)cc6)[nH]3)c2)[nH]c1 +n1c2nc3oc(nc3nc2oc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(n(c3c1ccnc3)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2nc3nc[nH]c3nc2n(c1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2ncc(cc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +N#Cc1ccc(c(C#N)c1)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +O=C1c2c(C(=O)C=C1)ccc(c2)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2c(nc(cc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccc1 +O=C1c2c(C(=O)N1)cccc2c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(scc1)cccc2c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2nccc(c2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2ncc(nc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccccc1 +c12nc3c(occ3)nc1n(cc2)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=C1c2c(C(=O)N1c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +N#Cc1cc(C#N)cc(C#N)c1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3)F)F)F +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccccc1 +c12c(c3c(cc(nc3)c3c4n(c5ccccc5)c5c(c4ccc3)c3c(C(c4c(cccc4)N3)(C)C)cc5)[nH]2)cncc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(oc1)cc(cc2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(oc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(scc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +O=C(c1ccccc1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3)C(F)(F)F +c1(c2nccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +n1c2c(nc3c(nc(o3)c3c4n(c5ccccc5)c5c(c4ccc3)c3c(C(c4c(cccc4)N3)(C)C)cc5)c2)oc1 +n1c2c(oc1c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c(noc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=c1c2c(n(cc1)c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +N#Cc1c(c(C#N)cc(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1)C#N +c12c(b3c4c(oc5c3c(o1)cc(c5)c1ccc(n3c5c(c6c3ccc3c6Nc6c(C3(C)C)cccc6)cccc5)cc1)cccc4)cccc2 +c12nc3c(oc(c3)c3ccc(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cc3)nc1[nH]cc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1ccc(n3c5c(c6c3ccc3c6Nc6c(C3(C)C)cccc6)cccc5)cc1)cccc4)cccc2 +c12c(ccc(c2)c2ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc2)cnc2c1cccc2 +c1(c2nccnc2)cccc(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(c(ccc2)c2ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +N#Cc1ccccc1c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +n1occ(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(n(c3c1ccnc3)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +c12c(n(cc1)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)ccnc2 +N#Cc1cc(C#N)cc(C#N)c1c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1cc(cc(C#N)c1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cc(cc2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)cnc2c1cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(sc3c1cc(cc3)c1cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +N#Cc1c(C#N)c(ccc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(c(ccc2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)[nH]c2ncccc12 +n1c2c(oc1)c(ccc2)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nccc(c2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)ncccc1 +c12ncc(nc1cccc2)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2ncc(nc2ncc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(ccnc2)[nH]cc1c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1cccc(C#N)c1c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +N#Cc1c(c(C#N)cc(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1)C#N +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3c(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cccc3)cc2)ccccc1 +c12c(c3c(cc(nc3)c3c(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cccc3)[nH]2)cncc1 +N#Cc1ccc(cc1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cc(cc2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)[nH]c2c1ccnc2 +O=C(c1cccc(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1)C(F)(F)F +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +c1(c2nccc(c2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)ncccc1 +c12ncc(nc1cccc2)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(c(cnc2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)[nH]cc1 +n1ccsc1c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(n(c3ncccc13)c1c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +n1c2nc3nc[nH]c3nc2n(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +O=C1c2c(C(=O)N1c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1cc3c(C(C)(c5c(cccc5)N3)C)cc1)cccc4)cccc2 +n1c2c(oc1)cc(cc2)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c12c(ccc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]c2c1ccnc2 +O=c1c2c(ccc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c1(c2nccnc2)cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +N#Cc1cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(c(ccc2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +N#Cc1ccccc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c1(c2ncccc2c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)ncccc1 +n1occc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +n1c2c(ncc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)ccc1 +n1occ(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +n1c(csc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(cccc2)[nH]cc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(cccc2)[nH]c(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1c3c(n(c5ccccc5)c5c3cc3c(C(c6c(cccc6)N3)(C)C)c5)ccc1)cccc4)cccc2 +c12c(occ1)cc1c(oc(c1)c1c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc1)c2 +c12c(cc(nc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]cc1 +N#Cc1ccc(c(C#N)c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(cc(cc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)cnc2c1cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(n(c5ccccc5)c5c3cc3c(C(c6c(cccc6)N3)(C)C)c5)ccc1)cccc4)cccc2 +O=c1c2c(ccc(c2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +N#Cc1cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(c(ccc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]c2c1ccnc2 +n1c2c(oc1)c(ccc2)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c1(c2ncccc2c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)ncccc1 +c12c(cccc2)[nH]c2nccc(c12)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1occc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1occ(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +O=c1c2c(cccc2)[nH]cc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1c2nc3nc(c4c5c(n(c6ccccc6)c6c5cc5c(C(c7c(cccc7)N5)(C)C)c6)ccc4)[nH]c3cc2[nH]c1 +c12c(n(c3ncccc13)c1c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc1)cccc2 +n1c2nc3nc[nH]c3cc2n(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +O=C1c2c(C(=O)C(=C1)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +O=C1c2c(C(=O)N1c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +O=C1C=CC(=O)N1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)cc2)ccccc1 +O=c1c2c(cccc2)[nH]c(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)[nH]c2c1cc(nc2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12nc3c(occ3)nc1[nH]c(c2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +N#Cc1c(C#N)cc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +N#Cc1ccc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)[nH]c2nc(ccc12)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(nc(cc2)c2cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc2)ccc1 +c12c(nn[nH]2)ccc(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)cnc2c1cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(nn[nH]2)cccc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(scc1)cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +O=C(c1ccccc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1)C(F)(F)F +c12ncc(nc1cccc2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2ncc(cc2ccc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12nc3c(occ3c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)nc1[nH]cc2 +O=c1c2c(cccc2)[nH]cc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(ccnc2)[nH]cc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(nc3c(nc(o3)c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)c2)oc1 +n1ccsc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(n(c1)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cc1c(nc[nH]1)c2 +n1c2c(nc3c(nco3)c2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)oc1 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3ccc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)c3)cc2)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c1)c2 +n1c2c(ccc1)cc(c1c2nccc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c1(c2nccnc2)cccc(c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(c(ccc2)c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2ncccc12 +c12c(nn[nH]2)cccc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(cccc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2c1ccnc2 +c12c(cccc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2ncccc12 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(ccnc2)[nH]cc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +n1c2c(nc3c(nc(o3)c3ccc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)c3)c2)oc1 +n1c2nc3oc(nc3nc2oc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +n1c(noc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(n(cc1)c1ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c1)ccnc2 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3)F)F)F +N#Cc1c(c(C#N)cc(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3)C#N +c12c(ccnc2)[nH]c(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +c12c(c3c(cc(nc3)c3c4n(c5ccccc5)c5c(c4ccc3)cc3c(C(c4c(cccc4)N3)(C)C)c5)[nH]2)cncc1 +c12c(cccc2)[nH]c2nc(ccc12)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(oc1)cc(cc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)cc2c(C(c3c(cccc3)N2)(C)C)c4)[nH]cc1 +c12c(cccc2)cnc2c1c(ccc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(oc1)c(ccc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2ncccc2c(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(nc3c(nc(o3)c3c4n(c5ccccc5)c5c(c4ccc3)cc3c(C(c4c(cccc4)N3)(C)C)c5)c2)oc1 +c1(C#N)cnc(nc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2nc3nc[nH]c3nc2n(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +N#Cc1cc(C#N)cc(C#N)c1c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +Fc1c(c(c(c(F)c1c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1)F)F)F +n1c2c(cc3c(nc[nH]3)c2c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c1 +n1c2c(c(c3c(nc[nH]3)c2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c1 +c12c(occ1)cc1c(oc(c1)c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)c2 +c12c(sc(c1)c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +O=c1c2c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]cc1 +c12c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +c12c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)cnc2c1cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)cnc2c1cc(cc2)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c1(c2ncccc2)nc(ccc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)cnc2c1cccc2c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(scc1)c(ccc2)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +n1c2c(nccc2)c(cc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(occ1)cc1c(occ1c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)c2 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3cc(n4c5c(c6c4cc4c(c6)Nc6c(C4(C)C)cccc6)cccc5)ccc3)cc2)ccccc1 +n1c2c(ccc1)cc(c1c2nccc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1ccc(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(ccc(c2)c2cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc2)cnc2c1cccc2 +c1(c2ncccc2)nc(ccc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=C(c1cccc(c1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1)C(F)(F)F +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +n1c2c(ccc1)ccc1c2nccc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2ncccc2c(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=c1c2c(cccc2)[nH]cc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2c1ccnc2c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(C#N)cncnc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1cnoc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c(noc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=c1c2c(n(cc1)c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3n(c4ccccc4)c4c(c3cc3c1C(c1c(cccc1)N3)(C)C)cccc4)cccc2 +c12c(occ1)c(c1c(occ1)c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +O=c1c2c(cccc2)[nH]c(c1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +c12c(cc(nc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]cc1 +N#Cc1c(c(C#N)c(cc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3)C#N +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +O=C1c2c(C(=O)N1)ccc(c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2nc(ccc2ccc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(cccc2)cnc2c1cc(cc2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2c(oc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(ccc(c2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]c2c1ccnc2 +O=C1c2c(C(=O)N1)cccc2c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +N#Cc1ccccc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(cccc2)[nH]c2nccc(c12)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(c2ncc(nc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +n1c2ncc(cc2ccc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(c2nc(cnc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +O=c1c2c(cccc2)[nH]cc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(ccnc2c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]cc1 +n1ccsc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1cnoc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(n(c3c1ccnc3)c1c3n(c4ccccc4)c4c(c3cc3c1C(c1c(cccc1)N3)(C)C)cccc4)cccc2 +O=C1c2c(C(=O)N1c1c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +c12c(occ1)c(c1c(occ1)c2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc2)ccccc1 +c12nc3c(oc(c3)c3c(n4c5c(c6c4cc4c(c6)Nc6c(C4(C)C)cccc6)cccc5)cccc3)nc1[nH]cc2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +N#Cc1ccc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cccc2)cnc2c1c(ccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +O=C(c1ccccc1c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1)C(F)(F)F +n1c2ncccc2c(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cccc2)[nH]c2nccc(c12)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12ncc(nc1cccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(ncc(c2)c2c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc2)ccc1 +c12c(cccc2)c(nc2c1cccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(nc3c(nco3)c2c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)oc1 +n1c2c(cc3c(nc[nH]3)c2c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)cc2)ccccc1 +c12c(sc(c1)c1ccc3c(C(C)(c4c(cccc4)N3)C)c1)cccc2 +c12nc3c(oc(c3)c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)nc1[nH]cc2 +N#Cc1c(C#N)cc(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +N#Cc1c(c(C#N)c(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1)C#N +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1ccc3c(C(C)(c5c(cccc5)N3)C)c1)cccc4)cccc2 +O=c1c2c(ccc(c2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]cc1 +c12c(c(ccc2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]c2ncccc12 +c12c(nn[nH]2)c(ccc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +n1c2ncc(cc2ccc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c1(c2nc(cnc2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)ccccc1 +c12nc3c(occ3c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)nc1[nH]cc2 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +O=C1C=C(C(=O)N1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2nc3nc[nH]c3c(c2[nH]c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(ccnc2)[nH]c(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nccnc2)ccc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +N#Cc1ccc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2)cnc2c1ccc(c2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cc(cc2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2ncccc12 +n1c2c(oc1)ccc(c2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(ccc(c2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2ncccc12 +c1(c2ncccc2)nc(ccc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nccnc2)cccc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +O=c1c2c(c(ccc2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]cc1 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3C(C)(c4c(cccc4)Nc3ccc1)C)cccc2 +c12c(scc1)c(ccc2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(oc1)c(ccc2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(scc1)cccc2c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2c1ccnc2 +O=c1c2c(cccc2c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1oc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(ccc1)ccc1c2ncc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2)[nH]c2ncc(cc12)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12nc3c(occ3)nc1[nH]cc2c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(cc3c(nc(c4c5C(C)(c6c(cccc6)Nc5ccc4)C)[nH]3)c2)[nH]c1 +n1ccsc1c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(c3c(n1c1c4C(C)(c5c(cccc5)Nc4ccc1)C)ccnc3)cncc2 +c12c(n(cc1)c1c3C(C)(c4c(cccc4)Nc3ccc1)C)ccnc2 +CC1(C)c2ccccc2-c2c(-c3cc(C#N)cc(C#N)c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cc4cccnc4c4ncccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4cccnc4n3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4cnc5ccccc5c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4[nH]c5ncccc5c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4[nH]ccc(=O)c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4c3cnc3ccccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4cnc5ccccc5c34)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4[nH]c5ncccc5c34)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc21 +CC1(C)c2ccccc2-c2c(-c3csc4ccccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3nc4nc5nc[nH]c5cc4[nH]3)cccc21 +CC1(C)c2ccccc2-c2c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc21 +CC1(C)c2ccccc2-c2c(-n3ccc4nc5ccoc5nc43)cccc21 +CC1(C)c2ccccc2-c2c(-n3cnc4cc5nc[nH]c5cc43)cccc21 +CC1(C)c2ccccc2-c2c(-n3cnc4nc5nc[nH]c5nc43)cccc21 +CC1(C)c2ccccc2-c2cc(-c3c(C#N)cccc3C#N)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(=O)c4ccccc4[nH]3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(C#N)c(C#N)c(C#N)c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc4cc5occc5cc4o3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc4nc5cc[nH]c5nc4o3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc(-c4ccccn4)n3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc(C#N)c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3C(=O)c=cC4=O)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3cnc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3ncc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3sc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ccnc4[nH]c5ccccc5c34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cnc4[nH]c5ccccc5c4c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3coc4cc5ccoc5cc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3c[nH]c4nc5occc5nc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3nccnc3-c3ccccc3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ncno3)ccc21 +CC1(C)c2ccccc2-c2cc(-n3ccc4cnccc43)ccc21 +CC1(C)c2ccccc2-c2ccc(-c3cc4c(cn3)[nH]c3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cc4cc5occc5cc4o3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc(C#N)c(C#N)c3C#N)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)ncc3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(cnc5ccccc54)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4[nH]c5cnccc5c4c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc4c(=O)cc[nH]c34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc4c3cnc3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccno3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnc(-c4ccccc4)cn3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnc4c(ccc5cccnc54)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnoc3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nccc4c3[nH]c3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nccc4[nH]c5ccncc5c34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ncon3)cc21 +CC1(C)c2ccccc2-c2ccc(-n3c4ccncc4c4cnccc43)cc21 +CC1(C)c2ccccc2-c2ccc(-n3nnc4ccccc43)cc21 +CC1(C)c2ccccc2-c2cccc(-c3c4nc[nH]c4cc4[nH]cnc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c21 +CC1(C)c2ccccc2-c2cccc(-c3cc4ccccc4s3)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc(C#N)c(C#N)c3C#N)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc4c(c3)ncc3ccccc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc4c(c3)[nH]c3ncccc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cccc(C(=O)C(F)(F)F)c3)c21 +O=C1c2c(C(=O)N1)cccc2c1c2C(C)(C)c3c(-c2ccc1)cccc3 +CC1(C)c2ccccc2-c2cccc(-c3cccc4sc5ccccc5c34)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccccc3C#N)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccnc4[nH]c5ccccc5c34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cscn3)c21 +CC1(C)c2ccccc2-c2cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c21 +CC1(C)c2ccccc2-c2cccc(-c3nc4nc5nc[nH]c5cc4[nH]3)c21 +O=C1C=CC(=O)N1N1c2c([C@H](C)c3c1cccc3)cccc2 +N#Cc1cccc(C#N)c1N1c2c(C(C)c3c1cccc3)cccc2 +n1c2nc3nc[nH]c3c(c2[nH]c1)N1c2c(C(C)c3c1cccc3)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)N3c4c(C(C)c5c3cccc5)cccc4)cc2)ccccc1 +N#Cc1cc(cc(C#N)c1)N1c2c(C(C)c3c1cccc3)cccc2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c(C(C)c3c1cccc3)cccc2 +c12c(sc3c1cc(cc3)N1c3c(C(C)c4c1cccc4)cccc3)cccc2 +O=c1c2c(ccc(c2)N2c3c(C(C)c4c2cccc4)cccc3)[nH]cc1 +N#Cc1cccc(c1)N1c2c(C(C)c3c1cccc3)cccc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3N1c2c(C(C)c3c1cccc3)cccc2 +O=C(c1ccccc1N1c2c(C(C)c3c1cccc3)cccc2)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1N1c2c(C(C)c3c1cccc3)cccc2 +n1oc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +n1c2c(ncc(c2)N2c3c(C(C)c4c2cccc4)cccc3)ccc1 +c12c(c3c(c(cnc3)N3c4c(C(C)c5c3cccc5)cccc4)[nH]2)cncc1 +c12nc3c(occ3N3c4c(C(C)c5c3cccc5)cccc4)nc1[nH]cc2 +c12c(c3c(n1N1c4c(C(C)c5c1cccc5)cccc4)ccnc3)cncc2 +n1c2nc3nc[nH]c3cc2n(c1)N1c2c(C(C)c3c1cccc3)cccc2 +N#Cc1cc(C#N)cc(C#N)c1c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3c4c([C@@H](C)c5c(cccc5)N4)ccc3)cc2)ccccc1 +N#Cc1c(c(C#N)c(cc1)c1c2c([C@H](C)c3c(cccc3)N2)ccc1)C#N +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +n1c2c(oc1)cc(cc2)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +c12c(scc1)ccc(c2)c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +c12c(c(ccc2)c2c3c([C@@H](C)c4c(cccc4)N3)ccc2)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nccc1c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +c12c(c(cnc2)c2c3c([C@H](C)c4c(cccc4)N3)ccc2)[nH]cc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +O=c1c2c(cccc2)[nH]cc1c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +N#Cc1cc(C#N)cc(C#N)c1c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2cc3c([C@H](C)c4c(cccc4)N3)cc2)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1cc3c([C@H](C)c5c(cccc5)N3)cc1)cccc4)cccc2 +c12c(c3c(cc(nc3)c3cc4c([C@H](C)c5c(cccc5)N4)cc3)[nH]2)cncc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(sc3c1ccc(c3)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +n1c2nc(ccc2ccc1)c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +c12c(cccc2)cnc2c1cc(cc2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(sc3c1cc(cc3)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +O=c1c2c(ccc(c2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(c(ccc2)c2cc3c([C@H](C)c4c(cccc4)N3)cc2)cnc2c1cccc2 +c12c(sc3c1c(ccc3)c1cc3c([C@H](C)c4c(cccc4)N3)cc1)cccc2 +c1(c2ncccc2c2cc3c([C@H](C)c4c(cccc4)N3)cc2)ncccc1 +n1c2c(ncc(c2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)ccc1 +c1(c2nc(cnc2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)ccccc1 +n1c2nc3nc(c4cc5c([C@@H](C)c6c(cccc6)N5)cc4)[nH]c3cc2[nH]c1 +c12c(n(c3c1ccnc3)c1cc3c([C@H](C)c4c(cccc4)N3)cc1)cccc2 +c12nc3c(occ3)nc1n(cc2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +O=C1C=C(C(=O)N1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +N#Cc1c(c(C#N)cc(c1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1)C#N +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2ccc3c([C@@H](C)c4c(cccc4)N3)c2)ccccc1 +c12c(cc(nc2)c2ccc3c([C@H](C)c4c(cccc4)N3)c2)[nH]cc1 +N#Cc1c(c(C#N)c(cc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1)C#N +N#Cc1ccc(cc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=C(c1ccc(cc1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1)C(F)(F)F +c12c(ccc(c2)c2ccc3c([C@H](C)c4c(cccc4)N3)c2)cnc2c1cccc2 +c12c(nn[nH]2)ccc(c1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1 +c12nccnc1c(ccc2)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c2c(oc1)c(ccc2)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c2c(oc1)cccc2c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +N#Cc1ccccc1c1ccc2c([C@@H](C)c3c(cccc3)N2)c1 +O=C(c1ccccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1)C(F)(F)F +c1(c2ncccc2c2ccc3c([C@H](C)c4c(cccc4)N3)c2)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=c1c2c(cccc2)[nH]cc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c(noc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=c1c2c(n(cc1)c1ccc3c([C@@H](C)c4c(cccc4)N3)c1)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(ccc2)Nc2c([C@@H]3C)cccc2)[nH]c1 +c12c(cccc2)[nH]c2c1cc(nc2)c1c2c(ccc1)Nc1c([C@@H]2C)cccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +n1c2c(oc1)ccc(c2)c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +c1(c2ncccc2c2c3c(ccc2)Nc2c([C@@H]3C)cccc2)ncccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1c2c(ccc1)Nc1c([C@@H]2C)cccc1 +n1c2c(cc3c(nc(c4c5c(ccc4)Nc4c([C@H]5C)cccc4)[nH]3)c2)[nH]c1 +n1ccsc1c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +n1cnoc1c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +Cc1-c2ccccc2-c2c(-c3c4ncoc4cc4ncoc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cc4c(cn3)[nH]c3ccccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cccc2-1 +C[C@@H]1c2c(-c3c1cccc3c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +C[C@H]1c2c(-c3c1cccc3c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +Cc1-c2ccccc2-c2c(-c3ccc4cc(N(C)C)ccc4c3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)cccc2-1 +C[C@H]1c2c(-c3c1cccc3c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +C[C@@H]1c2c(-c3c1cccc3c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +Cc1-c2ccccc2-c2c(-c3cccc4c3oc3ccccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4c3Oc3ccccc3O4)cccc2-1 +C[C@H]1c2c(-c3c1cccc3c1c3n(c4ccccc4)c4c(c3ccc1)cc1c(C(c3c(cccc3)N1)(C)C)c4)cccc2 +Cc1-c2ccccc2-c2c(-c3cccc4ncoc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4oc5ncccc5c34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4sccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4[nH]nnc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccccc3N(c3ccccc3)c3ccccc3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccccc3N)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cnc4sc5ncccc5c4c3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cncc4[nH]c5ccccc5c34)cccc2-1 +C[C@H]1c2c(-c3c1cccc3N1c3c(Sc4c1cccc4)cccc3)cccc2 +Cc1-c2ccccc2-c2c-1cccc2-n1nnc2ccccc21 +C[C@H]1c2c(-c3c1ccc(c3)N1c3c([C@@H](C)c4c1cccc4)cccc3)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)N1c3c(CCc4c1cccc4)cccc3)cccc2 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +Cc1-c2ccccc2-c2cc(-c3c4ccoc4cc4ccoc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3c4ncoc4cc4ncoc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cc4cc5occc5cc4o3)ccc2-1 +C[C@H]1c2c(-c3c1ccc(c3)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)Oc3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4cnc5ccccc5c4c3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4oc5ncccc5c4c3)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c([C@H](C)c4c(cccc4)N3)ccc1)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3cccc4c3-c3ccccc3C4(C)C)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +Cc1-c2ccccc2-c2cc(-c3cccc4c3cnc3ccccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3N(C)c3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3Oc3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3[nH]c3ccncc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c5nc[nH]c5c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4cc(N(C)C)ccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4nn[nH]c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4oc5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cn[nH]c3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3c[nH]c4ccccc4c3=O)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nc4cc5ocnc5cc4o3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nc4cc5scnc5cc4s3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nccc4[nH]c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccccc4c4ccncc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccncc4c4cnccc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3ccc4nc5ccoc5nc43)ccc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc(N(C)C)c4ccccc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4cc5occc5cc4o3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4ccccc4cc3N(C)C)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4ccccc4[nH]3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)N(C)c3ccccc3O4)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)sc3ncccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(N(C)C)cccc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4cccc(N(C)C)c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4occc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4[nH]c5ccccc5c(=O)c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3cnc3ccccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3oc3ccccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3sc3ncccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4[nH]c5ccccc5c(=O)c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccn[nH]3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cn[nH]c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3coc4cc5ccoc5cc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3coc4cc5[nH]ccc5cc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3c[nH]c4ccccc4c3=O)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3nc4ccccc4s3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3nccc4[nH]c5ccccc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-n3c4ccccc4c(=O)c4ccccc43)cc2-1 +Cc1-c2ccccc2-c2ccc(-n3c4ccccc4c4cnccc43)cc2-1 +Cc1-c2ccccc2-c2cccc(-c3cc(=O)c4ccccc4[nH]3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc(N(C)C)cc4ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4c(cn3)[nH]c3ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4ccccc4cc3N(C)C)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc(N(C)C)c4ccccc34)c2-1 +C[C@@H]1c2c(-c3c1c(ccc3)c1ccc3c(c1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)N(C)c3ccccc3O4)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)oc3ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)c2-1 +C[C@H]1c2c(-c3c1c(ccc3)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +Cc1-c2ccccc2-c2cccc(-c3ccc4c5ccccc5c5nccnc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cc(N(C)C)ccc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4ccc(N(C)C)cc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4ccsc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cc[nH]c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cnc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4oc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4[nH]c5ccncc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4c(N(C)C)cccc34)c2-1 +C[C@@H]1c2c(-c3c1c(ccc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +C[C@H]1c2c(-c3c1c(ccc3)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +Cc1-c2ccccc2-c2cccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cccc(N(C)C)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4ccsc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cc[nH]c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cnc5ccccc5c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4occc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]c5ccccc5c(=O)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]nnc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccccc3N)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cnc4sc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4cc5scnc5cc4s3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4ccccc4c4ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4ccccc4s3)c2-1 +Cc1-c2ccccc2-c2cccc(-n3c4ccncc4c4cnccc43)c2-1 +Cc1-c2ccccc2-c2cccc(-n3ccc(=O)c4ccccc43)c2-1 +Cc1-c2ccccc2-c2cccc(-n3cccn3)c2-1 +Cc1c(C)c(-c2c(F)c(F)c(F)c(F)c2F)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2c3ccoc3cc3ccoc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2c3[nH]cnc3cc3nc[nH]c23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cc(C#N)cc(C#N)c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cc3nc4ccoc4nc3[nH]2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc(-c3cnccn3)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc(C#N)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(c2)-c2ccccc2-s-3(=O)=O)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(c2)[nH]c2ncccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(n2)[nH]c2ccccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3ncc4ccccc4c3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3ncoc3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc(-c3ccccn3)n2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc(C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3c2-s(=O)(=O)-c2ccccc2-3)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3c2cnc2ccccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3ocnc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccccc2C(=O)C(F)(F)F)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccccc2C(=O)c2ccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cnc3ccccc3n2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cnc3cccnc3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2c3ccccc3c3cccnc32)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2ccc(=O)c3ccccc32)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2ccc3nc4ccoc4nc32)c2c(c1C)c1ccccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3c4nc[nH]c4cc4[nH]cnc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc(C#N)c(C#N)c(C#N)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc(C#N)cc(C#N)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4cccnc4c4ncccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4cnccc4[nH]3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4nc5cc[nH]c5nc4o3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4[nH]c5ccncc5c4cn3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc(C#N)c(C#N)c3C#N)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4c(c3)sc3ccccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4ccc5cccnc5c4n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4nccnc4c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(-c4ccccn4)n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(C(=O)C(F)(F)F)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4c(=O)cc[nH]c34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4c3[nH]c3cnccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4nn[nH]c34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccnc(-c4ccccn4)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cnc4nccnc4n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3nccc4c3[nH]c3ccccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ncon3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-n3cnc4nc5nc[nH]c5cc43)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-n3nnc4ccccc43)cccc1n2C +O=C1c2c(C(=O)N1c1cc3c4c(n(c3cc1)C)cc(C)c(c4C)C)cccc2 +Cc1cc2c(c(C)c1C)c1cc(-c3c(C#N)cccc3C#N)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4ccccc4s3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4nc5ccoc5nc4[nH]3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4[nH]ccc4cn3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)-c(C)-c3ccccc3-4)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)sc3ccccc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4nccnc4c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc(C#N)c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc(C(=O)C(F)(F)F)c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc4c3C(=O)c=cC4=O)ccc1n2C +O=C1c2c(C(=O)N1)cccc2c1cc2c3c(n(c2cc1)C)cc(C)c(c3C)C +Cc1cc2c(c(C)c1C)c1cc(-c3ccccc3C#N)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccnc4ncccc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccon3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cncc4[nH]c5ccccc5c34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cnoc3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3coc4cc5ccoc5cc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ncon3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-n3c4ccccc4c4cccnc43)ccc1n2C +O=C1c2c(C(=O)N1c1ccc3c4c(n(c3c1)C)cc(C)c(c4C)C)cccc2 +O=C1C=CC(=O)N1c1ccc2c3c(n(c2c1)C)cc(C)c(c3C)C +Cc1cc2c(c(C)c1C)c1ccc(-c3c(C#N)cc(C#N)cc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3c4nc[nH]c4cc4[nH]cnc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc(C#N)cc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4c(=O)cc[nH]c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4ccsc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4nn[nH]c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4sccc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4[nH]c5cnccc5c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4[nH]nnc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc4sc5ccccc5c34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc4[nH]ccc(=O)c34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cnc4c(ccc5cccnc54)c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3c[nH]c4ccncc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3nccc4c3[nH]c3ccccc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3nccc4[nH]ccc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ncncc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cc4[nH]c5ccncc5c4cn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(C#N)c(C#N)c3C#N)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(C#N)cc3C#N)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4ncccc4n3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4[nH]c5cnccc5c4c3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4[nH]ccc(=O)c4c3)c1n2C +O=C1c2c(C(=O)N1)cccc2c1c2c(c3c(n2C)cc(C)c(c3C)C)ccc1 +Cc1cc2c(c(C)c1C)c1cccc(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cccc4[nH]ccc(=O)c34)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cccnc3-c3ccccn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cnc4cccnc4c3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cncc4c3[nH]c3ccncc34)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cscn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ncc(C#N)cn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3nccc4[nH]ccc34)c1n2C +Cc1cccc2c1[nH]c1c(C)c(-c3c(C#N)cccc3C#N)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3c4ncoc4nc4ocnc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccc(F)cc5)n4)ccc3F)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc(C#N)c(C#N)c(C#N)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc4cccnc4c4ncccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc4[nH]ccc4cn3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc(C#N)c(C#N)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc(C#N)cc3C#N)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc4sc5ccccc5c4c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc4[nH]nnc4c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc(C(=O)C(F)(F)F)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3ncc3ccccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3[nH]c3ncccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4ncoc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccnc3-c3ccccn3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccnc(-c4ccccn4)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccno3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cnc4ccccc4n3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3coc4nc5[nH]ccc5nc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3c[nH]c4ccncc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-n3c4ccccc4c4cccnc43)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-n3ccc(=O)c4ccccc43)ccc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3(C)-c4ccccc4-c4ccccc4-3)cc12 +O=C1C=C(C(=O)N1)c1cc2c3c(c(C)ccc3)[nH]c2c(C)c1 +Cc1cccc2c1[nH]c1c(C)cc(-c3c4[nH]cnc4nc4nc[nH]c34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cc(C#N)cc(C#N)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cc4[nH]c5ccncc5c4cn3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc(C#N)c(C#N)c3C#N)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc(C#N)cc3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)cc12 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c3c(c(C)ccc3)[nH]c2c(C)c1 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)[nH]c3ncccc34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4nccnc4c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4ocnc4c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(-c4ccccn4)n3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(-c4cnccn4)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4c3-c(C)-c3ccccc3-4)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4c3ncc3ccccc34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4[nH]c5ncccc5c34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccon3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cnc(-c4ccccc4)cn3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cnc4ccccc4n3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3csc4ccccc34)cc12 +O=C1c2c(C(=O)N1c1c3c4c(c(C)ccc4)[nH]c3c(C)cc1)cccc2 +Cc1cccc2c1[nH]c1c(C)ccc(-c3c4ccoc4cc4ccoc34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc(C#N)c(C#N)c(C#N)c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc4[nH]ccc4cn3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(-c4cnccn4)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C#N)c(C#N)c3C#N)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C(=O)C(F)(F)F)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4c(=O)cc[nH]c4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4cnc5ccccc5c4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4[nH]nnc4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cccc4c3-c(C)-c3ccccc3-4)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cccc4[nH]c5ncccc5c34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccnc4cccnc34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cnc4c(ccc5cccnc54)c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cnc4cccnc4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cncs3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cscn3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-n3cnc4cc5nc[nH]c5cc43)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-n3cnc4nc5nc[nH]c5cc43)c12 +O=C1C=C(C(=O)N1)n1c2c(c3c1c(C)ccc3)cccc2C +Cc1cccc2c3cccc(C)c3n(-c3c4ncoc4nc4ocnc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3c4[nH]cnc4cc4nc[nH]c34)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccc(F)cc5)n4)ccc3F)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc(=O)c4ccccc4[nH]3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc4nc5cc[nH]c5nc4o3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc4[nH]ccc4cn3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(c3)-c(C)-c3ccccc3-4)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(c3)-c3ccccc3-c-4C)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(n3)[nH]c3ccccc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4ncc5ccccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4[nH]c5ncccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cccc4c3-c3ccccc3-s-4(=O)=O)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccno3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4ccccc4n3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4cccnc4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4[nH]c5ccccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cncc4[nH]c5ccccc5c34)c12 +Cc1cccc2c3cccc(C)c3n(-c3csc4ccccc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3nc4nc5nc[nH]c5nc4[nH]3)c12 +Cc1cccc2c3cccc(C)c3n(-c3nccc4[nH]c5ccncc5c34)c12 +Cc1cccc2c3cccc(C)c3n(-n3ccc4nc5ccoc5nc43)c12 +CN(C)c1c(-c2(C)-c3ccccc3-c3ccccc3-2)ccc2ccccc12 +O=C1C=CC(=O)N1c1c(N(C)C)c2c(cc1)cccc2 +CN(C)c1c(-c2c3[nH]cnc3nc3nc[nH]c23)ccc2ccccc12 +CN(C)c1c(-c2cc(C#N)c(C#N)c(C#N)c2)ccc2ccccc12 +CN(C)c1c(-c2cc(F)ccc2-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)ccc2ccccc12 +CN(C)c1c(-c2cccc(C(=O)C(F)(F)F)c2)ccc2ccccc12 +CN(C)c1c(-c2cccc3c2[nH]c2ncccc23)ccc2ccccc12 +CN(C)c1c(-c2cccc3cnc4ccccc4c23)ccc2ccccc12 +CN(C)c1c(-c2cccc3ncoc23)ccc2ccccc12 +CN(C)c1c(-c2ccon2)ccc2ccccc12 +CN(C)c1c(-c2cnoc2)ccc2ccccc12 +CN(C)c1c(-c2c[nH]c3ccncc23)ccc2ccccc12 +CN(C)c1c(-c2nc3cc4nc[nH]c4cc3[nH]2)ccc2ccccc12 +CN(C)c1c(-c2nc3ccccc3o2)ccc2ccccc12 +CN(C)c1c(-n2c3ccccc3c3cccnc32)ccc2ccccc12 +CN(C)c1cc(-c2c3ncoc3nc3ocnc23)cc2ccccc12 +CN(C)c1cc(-c2c3[nH]cnc3nc3nc[nH]c23)cc2ccccc12 +CN(C)c1cc(-c2cc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2C(=O)c2ccccc2)c2ccccc2c1 +CN(C)c1cc(-c2cc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2C(=O)c2ccccc2)cc2ccccc12 +CN(C)c1cc(-c2cc(=O)c3ccccc3[nH]2)c2ccccc2c1 +CN(C)c1cc(-c2cc3cccnc3c3ncccc23)c2ccccc2c1 +CN(C)c1cc(-c2ccc(-c3cnccn3)cc2)c2ccccc2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(cccc2)cc(N(C)C)c1 +CN(C)c1cc(-c2ccc3c(c2)[nH]c2ncccc23)cc2ccccc12 +CN(C)c1cc(-c2ccc3c(cnc4ccccc43)c2)c2ccccc2c1 +CN(C)c1cc(-c2ccc3c(cnc4ccccc43)c2)cc2ccccc12 +CN(C)c1cc(-c2ccc3c(n2)[nH]c2ccccc23)cc2ccccc12 +CN(C)c1cc(-c2ccc3ncoc3c2)cc2ccccc12 +CN(C)c1cc(-c2ccc3nn[nH]c3c2)c2ccccc2c1 +CN(C)c1cc(-c2ccc3[nH]c4cnccc4c3c2)cc2ccccc12 +CN(C)c1cc(-c2cccc(-c3cnccn3)c2)c2ccccc2c1 +CN(C)c1cc(-c2cccc(C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c2)cc2ccccc12 +CN(C)c1cc(-c2cccc3c(=O)cc[nH]c23)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2C(=O)c=cC3=O)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2ncc2ccccc23)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2[nH]c2cnccc23)c2ccccc2c1 +CN(C)c1cc(-c2cccc3c2[nH]c2cnccc23)cc2ccccc12 +CN(C)c1cc(-c2cccc3nccnc23)c2ccccc2c1 +CN(C)c1cc(-c2cccc3ocnc23)c2ccccc2c1 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c2ccccc2c1 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc2ccccc12 +CN(C)c1cc(-c2cccnc2-c2ccccn2)c2ccccc2c1 +CN(C)c1cc(-c2ccnc(-c3ccccn3)c2)c2ccccc2c1 +CN(C)c1cc(-c2ccnc3c2ccc2cccnc23)c2ccccc2c1 +CN(C)c1cc(-c2ccnc3cccnc23)c2ccccc2c1 +CN(C)c1cc(-c2coc3nc4[nH]ccc4nc23)cc2ccccc12 +CN(C)c1cc(-c2csc3ccccc23)c2ccccc2c1 +CN(C)c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2ccccc2c1 +CN(C)c1cc(-c2nccs2)cc2ccccc12 +CN(C)c1cc(-n2cnc3cc4nc[nH]c4cc32)cc2ccccc12 +CN(C)c1cc2ccccc2cc1-c1(C)-c2ccccc2-c2ccccc2-1 +O=C1C=C(C(=O)N1)c1c(N(C)C)cc2c(c1)cccc2 +O=C1c2c(C(=O)N1c1c(N(C)C)cc3c(c1)cccc3)cccc2 +O=C1C=CC(=O)N1c1c(N(C)C)cc2c(c1)cccc2 +CN(C)c1cc2ccccc2cc1-c1c(C#N)cc(C#N)cc1C#N +CN(C)c1cc2ccccc2cc1-c1c(F)c(F)c(F)c(F)c1F +CN(C)c1cc2ccccc2cc1-c1cc(C#N)c(C#N)c(C#N)c1 +CN(C)c1cc2ccccc2cc1-c1cc2c3c(c1)Oc1ccccc1B3c1ccccc1O2 +CN(C)c1cc2ccccc2cc1-c1cc2ccccc2s1 +CN(C)c1cc2ccccc2cc1-c1cc2cnccc2[nH]1 +CN(C)c1cc2ccccc2cc1-c1cc2nc3ccoc3nc2[nH]1 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)-c1ccccc1-s-2(=O)=O +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)-s(=O)(=O)-c1ccccc1-2 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)B1c3ccccc3Oc3cccc(c31)O2 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)Oc1cccc3c1B2c1ccccc1O3 +CN(C)c1cc2ccccc2cc1-c1ccc2cnc3ccccc3c2c1 +CN(C)c1cc2ccccc2cc1-c1cccc2ocnc12 +CN(C)c1cc2ccccc2cc1-c1ccnc2c1ccc1cccnc12 +CN(C)c1cc2ccccc2cc1-c1ccnc2ncccc12 +CN(C)c1cc2ccccc2cc1-c1cncs1 +CN(C)c1cc2ccccc2cc1-c1coc2nc3[nH]ccc3nc12 +CN(C)c1cc2ccccc2cc1-c1nccnc1-c1ccccc1 +CN(C)c1cc2ccccc2cc1-n1cnc2nc3nc[nH]c3cc21 +CN(C)c1ccc(-c2=cC(=O)c3ccccc3C2=O)c2ccccc12 +CN(C)c1ccc(-c2c(F)c(F)c(F)c(F)c2F)c2ccccc12 +CN(C)c1ccc(-c2cc(-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)ccc2F)c2ccccc12 +CN(C)c1ccc(-c2cc3cnccc3[nH]2)c2ccccc12 +CN(C)c1ccc(-c2cc3[nH]c4ccncc4c3cn2)c2ccccc12 +CN(C)c1ccc(-c2ccc(-c3cnccn3)cc2)c2ccccc12 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c(N(C)C)cc1)cccc2 +CN(C)c1ccc(-c2ccc3c(c2)sc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2ccc3ccsc3c2)c2ccccc12 +CN(C)c1ccc(-c2ccc3[nH]nnc3c2)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2ncc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2sc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2[nH]c2cnccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3nccnc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3ocnc23)c2ccccc12 +CN(C)c1ccc(-c2ccnc3cccnc23)c2ccccc12 +CN(C)c1ccc(-c2ccno2)c2ccccc12 +CN(C)c1ccc(-c2nccnc2-c2ccccc2)c2ccccc12 +CN(C)c1ccc(-c2ncon2)c2ccccc12 +CN(C)c1ccc(-n2c3ccncc3c3cnccc32)c2ccccc12 +CN(C)c1ccc(-n2ccc3cnccc32)c2ccccc12 +CN(C)c1ccc(-n2cnc3cc4nc[nH]c4cc32)c2ccccc12 +CN(C)c1ccc(-n2cnc3nc4nc[nH]c4nc32)c2ccccc12 +CN(C)c1ccc2c(-c3c(F)c(F)c(F)c(F)c3F)cccc2c1 +CN(C)c1ccc2c(-c3c4[nH]cnc4nc4nc[nH]c34)cccc2c1 +CN(C)c1ccc2c(-c3cc4[nH]c5ccncc5c4cn3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4c(=O)cc[nH]c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4c(c3)ncc3ccccc34)cccc2c1 +CN(C)c1ccc2c(-c3ccc4cccnc4n3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4cnc5ccccc5c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4[nH]ccc(=O)c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc2c1 +CN(C)c1ccc2c(-c3ccno3)cccc2c1 +CN(C)c1ccc2c(-c3ncc(C#N)cn3)cccc2c1 +CN(C)c1ccc2c(-n3ccc(=O)c4ccccc43)cccc2c1 +CN(C)c1ccc2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc2c1 +CN(C)c1ccc2cc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)ccc2c1 +CN(C)c1ccc2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc2c1 +CN(C)c1ccc2cc(-c3cc4[nH]c5ccncc5c4cn3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc(-c4cnccn4)cc3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc4nn[nH]c4c3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc4sccc4c3)ccc2c1 +CN(C)c1ccc2cc(-c3cccc4c3sc3ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3cccc4ocnc34)ccc2c1 +CN(C)c1ccc2cc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2c1 +CN(C)c1ccc2cc(-c3ccccc3C#N)ccc2c1 +CN(C)c1ccc2cc(-c3cnc4nccnc4n3)ccc2c1 +CN(C)c1ccc2cc(-c3csc4ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3nc4ccccc4c4ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3nc4nc5nc[nH]c5nc4[nH]3)ccc2c1 +CN(C)c1ccc2cc(-c3nccs3)ccc2c1 +CN(C)c1ccc2cc(-n3c4ccccc4c4ccncc43)ccc2c1 +O=C1C=C(C(=O)N1)c1ccc2c(c1)cc(N(C)C)cc2 +CN(C)c1ccc2ccc(-c3cc(=O)c4ccccc4[nH]3)cc2c1 +CN(C)c1ccc2ccc(-c3ccc(C#N)c(C#N)c3C#N)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4c(c3)C(=O)c=cC4=O)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4ncccc4n3)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4[nH]c5ncccc5c4c3)cc2c1 +CN(C)c1ccc2ccc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cc2c1 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c1)cc(N(C)C)cc2 +CN(C)c1ccc2ccc(-c3cccc4ccsc34)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4[nH]c5ncccc5c34)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4[nH]ccc(=O)c34)cc2c1 +CN(C)c1ccc2ccc(-c3ccnc4ncccc34)cc2c1 +CN(C)c1ccc2ccc(-c3cncc4cc[nH]c34)cc2c1 +CN(C)c1ccc2ccc(-n3ccc4cnccc43)cc2c1 +CN(C)c1ccc2ccc(-n3cnc4nc5nc[nH]c5nc43)cc2c1 +CN(C)c1ccc2cccc(-c3c4[nH]cnc4cc4nc[nH]c34)c2c1 +CN(C)c1ccc2cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c2c1 +CN(C)c1ccc2cccc(-c3cc(F)ccc3-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)c2c1 +CN(C)c1ccc2cccc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)c2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccc(N(C)C)c2)ccc1 +CN(C)c1ccc2cccc(-c3ccc4c(c3)[nH]c3ncccc34)c2c1 +CN(C)c1ccc2cccc(-c3ccc4c(n3)[nH]c3ccccc34)c2c1 +CN(C)c1ccc2cccc(-c3ccc4ncoc4c3)c2c1 +CN(C)c1ccc2cccc(-c3cccc(C(=O)C(F)(F)F)c3)c2c1 +CN(C)c1ccc2cccc(-c3cccc4c(=O)cc[nH]c34)c2c1 +CN(C)c1ccc2cccc(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)c2c1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc(N(C)C)c2)ccc1 +CN(C)c1ccc2cccc(-c3cccc4ccsc34)c2c1 +CN(C)c1ccc2cccc(-c3cccnc3-c3ccccn3)c2c1 +CN(C)c1ccc2cccc(-c3ccnc4c3ccc3cccnc34)c2c1 +CN(C)c1ccc2cccc(-c3ccnc4cccnc34)c2c1 +CN(C)c1ccc2cccc(-c3cnc4c(ccc5cccnc54)c3)c2c1 +CN(C)c1ccc2cccc(-c3cnc4ncccc4c3)c2c1 +CN(C)c1ccc2cccc(-c3c[nH]c4ccncc34)c2c1 +CN(C)c1ccc2cccc(-c3nccs3)c2c1 +CN(C)c1ccc2cccc(-n3c4ccccc4c4ccncc43)c2c1 +CN(C)c1ccc2ccccc2c1-c1cc(C(=O)c2ccccc2)ccc1-c1nc(-c2ccc(F)cc2)nc(-c2ccc(F)cc2)n1 +CN(C)c1ccc2ccccc2c1-c1cc(F)ccc1-c1nc(-c2ccc(F)cc2)nc(-c2ccc(C(=O)c3ccccc3)cc2)n1 +CN(C)c1ccc2ccccc2c1-c1cc2nc3ccoc3nc2[nH]1 +CN(C)c1ccc2ccccc2c1-c1cc2nc3cc[nH]c3nc2o1 +CN(C)c1ccc2ccccc2c1-c1ccc(C#N)c(C#N)c1C#N +CN(C)c1ccc2ccccc2c1-c1ccc2c(cnc3ccccc32)c1 +CN(C)c1ccc2ccccc2c1-c1ccc2ccsc2c1 +CN(C)c1ccc2ccccc2c1-c1cccc(C#N)c1 +CN(C)c1ccc2ccccc2c1-c1cccc(C(=O)c2ccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc2)c1 +CN(C)c1ccc2ccccc2c1-c1cccc2c1-s(=O)(=O)-c1ccccc1-2 +O=C1c2c(C(=O)N1)cccc2c1c(N(C)C)ccc2c1cccc2 +CN(C)c1ccc2ccccc2c1-c1cnc2ccccc2n1 +CN(C)c1ccc2ccccc2c1-c1cncs1 +CN(C)c1ccc2ccccc2c1-c1ncon1 +CN(C)c1cccc2c(-c3c(C#N)cc(C#N)cc3C#N)cccc12 +CN(C)c1cccc2c(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cccc12 +CN(C)c1cccc2c(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cccc12 +CN(C)c1cccc2c(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc12 +CN(C)c1cccc2c(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)cccc12 +CN(C)c1cccc2c(-c3ccc4ncc5ccccc5c4c3)cccc12 +CN(C)c1cccc2c(-c3ccc4ncccc4n3)cccc12 +CN(C)c1cccc2c(-c3ccc4[nH]nnc4c3)cccc12 +CN(C)c1cccc2c(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cccc12 +CN(C)c1cccc2c(-c3cccc4c3[nH]c3cnccc34)cccc12 +CN(C)c1cccc2c(-c3cccc4c3[nH]c3ncccc34)cccc12 +CN(C)c1cccc2c(-c3cccc4ccsc34)cccc12 +CN(C)c1cccc2c(-c3cccc4ncc5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3cccc4sc5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3cccc4[nH]ccc(=O)c34)cccc12 +CN(C)c1cccc2c(-c3ccccc3C(=O)C(F)(F)F)cccc12 +CN(C)c1cccc2c(-c3ccnc4cccnc34)cccc12 +CN(C)c1cccc2c(-c3cncc4[nH]c5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3c[nH]c4ccncc34)cccc12 +CN(C)c1cccc2c(-n3c4ccccc4c4ccncc43)cccc12 +CN(C)c1cccc2cc(-c3c(C#N)cccc3C#N)ccc12 +CN(C)c1cccc2cc(-c3ccc(-c4cnccn4)cc3)ccc12 +CN(C)c1cccc2cc(-c3ccc(C#N)cc3)ccc12 +CN(C)c1cccc2cc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)ccc12 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(c(N(C)C)ccc2)cc1 +CN(C)c1cccc2cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +CN(C)c1cccc2cc(-c3ccc4nn[nH]c4c3)ccc12 +CN(C)c1cccc2cc(-c3cccc(C#N)c3)ccc12 +CN(C)c1cccc2cc(-c3cccc4[nH]c5cnccc5c34)ccc12 +CN(C)c1cccc2cc(-c3cccc4[nH]nnc34)ccc12 +CN(C)c1cccc2cc(-c3ccccc3-c3cnccn3)ccc12 +CN(C)c1cccc2cc(-c3cnc4ncccc4c3)ccc12 +CN(C)c1cccc2cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +CN(C)c1cccc2cc(-c3cscn3)ccc12 +CN(C)c1cccc2cc(-c3c[nH]c4ccccc4c3=O)ccc12 +CN(C)c1cccc2cc(-c3c[nH]c4ccncc34)ccc12 +CN(C)c1cccc2cc(-c3nccc4c3[nH]c3ccccc34)ccc12 +CN(C)c1cccc2cc(-c3nccc4[nH]ccc34)ccc12 +CN(C)c1cccc2cc(-c3ncncc3C#N)ccc12 +CN(C)c1cccc2ccc(-c3cc(=O)c4ccccc4[nH]3)cc12 +CN(C)c1cccc2ccc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cc12 +CN(C)c1cccc2ccc(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cc12 +CN(C)c1cccc2ccc(-c3cccc4c3[nH]c3ncccc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4ocnc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4sccc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4[nH]c5ncccc5c34)cc12 +CN(C)c1cccc2ccc(-c3cccc4[nH]nnc34)cc12 +CN(C)c1cccc2ccc(-c3ccnc4cccnc34)cc12 +CN(C)c1cccc2ccc(-c3ccno3)cc12 +CN(C)c1cccc2ccc(-c3coc4cc5ccoc5cc34)cc12 +CN(C)c1cccc2ccc(-n3ccc(=O)c4ccccc43)cc12 +CN(C)c1cccc2cccc(-c3c(C#N)cc(C#N)cc3C#N)c12 +CN(C)c1cccc2cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c12 +CN(C)c1cccc2cccc(-c3cc(C#N)cc(C#N)c3)c12 +CN(C)c1cccc2cccc(-c3cc4cc5occc5cc4o3)c12 +CN(C)c1cccc2cccc(-c3ccc(C#N)cc3C#N)c12 +CN(C)c1cccc2cccc(-c3ccc4cccnc4n3)c12 +CN(C)c1cccc2cccc(-c3ccc4ocnc4c3)c12 +CN(C)c1cccc2cccc(-c3cccc4c3[nH]c3ncccc34)c12 +CN(C)c1cccc2cccc(-c3cccc4[nH]c5ncccc5c34)c12 +CN(C)c1cccc2cccc(-c3coc4cc5ccoc5cc34)c12 +CN(C)c1cccc2cccc(-c3coc4nc5[nH]ccc5nc34)c12 +CN(C)c1cccc2cccc(-c3nc4ccccc4c4ccccc34)c12 +CN(C)c1cccc2cccc(-c3nc4ccccc4o3)c12 +CN(C)c1cccc2cccc(-c3nccc4[nH]c5ccncc5c34)c12 +CN(C)c1cccc2cccc(-c3ncncc3C#N)c12 +CN(C)c1cccc2cccc(-n3c4ccccc4c4ccncc43)c12 +CN(C)c1cccc2cccc(-n3ccc4nc5ccoc5nc43)c12 +CN(C)c1cccc2cccc(-n3cnc4cc5nc[nH]c5cc43)c12 +CN(C)c1cccc2cccc(-n3cnc4nc5nc[nH]c5nc43)c12 +CN1c2ccccc2N(C)c2c(-c3=cC(=O)c4ccccc4C3=O)cccc21 +CN1c2ccccc2N(C)c2c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc4[nH]c5ccncc5c4cn3)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc4[nH]ccc4cn3)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4c(c3)sc3ccccc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4cccnc4n3)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4ncc5ccccc5c4c3)cccc21 +O=C1c2c(C(=O)N1)cccc2c1c2N(C)c3c(N(C)c2ccc1)cccc3 +CN1c2ccccc2N(C)c2c(-c3cccc4ocnc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3cnc4cccnc4c3)cccc21 +CN1c2ccccc2N(C)c2c(-c3c[nH]c4nc5occc5nc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3ncc(C#N)cn3)cccc21 +CN1c2ccccc2N(C)c2c1cccc2-n1ccc(=O)c2ccccc21 +CN1c2ccccc2N(C)c2c1cccc2-n1nnc2ccccc21 +CN1c2ccccc2N(C)c2cc(-c3=cC(=O)c4ccccc4C3=O)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cc4ccccc4s3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc(C#N)c(C#N)c3C#N)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc4ncoc4c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc4ccsc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccnc(-c4ccccn4)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cnc4c(ccc5cccnc54)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cncc(-c4ccccc4)n3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cncc4[nH]c5ccccc5c34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3csc4ccccc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3c[nH]c4nc5occc5nc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ncon3)ccc21 +CN1c2ccccc2N(C)c2cc(-n3ccc(=O)c4ccccc43)ccc21 +CN1c2ccccc2N(C)c2cc(-n3ccc4cnccc43)ccc21 +O=C1C=C(C(=O)N1)c1c2Oc3c(N(C)c2ccc1)cccc3 +CN1c2ccccc2Oc2c(-c3c(C#N)cc(C#N)cc3C#N)cccc21 +CN1c2ccccc2Oc2c(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)ccc3C(=O)c3ccccc3)cccc21 +CN1c2ccccc2Oc2c(-c3cc4cnccc4[nH]3)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)C(=O)c=cC4=O)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)[nH]c3ncccc34)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4nn[nH]c4c3)cccc21 +CN1c2ccccc2Oc2c(-c3cccc(-c4cnccn4)c3)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3ncc3ccccc34)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4cnc5ccccc5c34)cccc21 +CN1c2ccccc2Oc2c(-c3ccon3)cccc21 +CN1c2ccccc2Oc2c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc21 +CN1c2ccccc2Oc2c(-c3ncc(C#N)cn3)cccc21 +CN1c2ccccc2Oc2c(-c3ncno3)cccc21 +CN1c2ccccc2Oc2c1cccc2-n1nnc2ccccc21 +CN1c2ccccc2Oc2cc(-c3(C)-c4ccccc4-c4ccccc4-3)ccc21 +CN1c2ccccc2Oc2cc(-c3cc4[nH]c5ccncc5c4cn3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(-c4ccccn4)nc3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(C#N)c(C#N)c3C#N)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(C(=O)C(F)(F)F)cc3)ccc21 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2Oc3c(N(C)c2cc1)cccc3 +CN1c2ccccc2Oc2cc(-c3ccc4ccc5cccnc5c4n3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4cccnc4n3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4ncc5ccccc5c4c3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4nn[nH]c4c3)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc4[nH]c5ncccc5c34)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc4[nH]nnc34)ccc21 +CN1c2ccccc2Oc2cc(-c3cncc4c3[nH]c3ccncc34)ccc21 +CN1c2ccccc2Oc2cc(-c3cncc4cc[nH]c34)ccc21 +CN1c2ccccc2Oc2cc(-c3c[nH]c4ccncc34)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4ccccc4c4ccccc34)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4ccccc4o3)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc21 +CN1c2ccccc2Oc2cc(-c3nccc4c3[nH]c3ccccc34)ccc21 +CN1c2ccccc2Oc2cc(-n3cnc4nc5nc[nH]c5cc43)ccc21 +CN1c2ccccc2Oc2ccc(-c3c(C#N)cccc3C#N)cc21 +CN1c2ccccc2Oc2ccc(-c3c4ccoc4cc4ccoc34)cc21 +CN1c2ccccc2Oc2ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc21 +CN1c2ccccc2Oc2ccc(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cc21 +CN1c2ccccc2Oc2ccc(-c3cc4nc5ccoc5nc4[nH]3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc(C#N)c(C#N)c3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cc21 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2Oc3c(N(C)c2c1)cccc3 +CN1c2ccccc2Oc2ccc(-c3ccc4ccsc4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc4nn[nH]c4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3cccc4c3-c3ccccc3-s-4(=O)=O)cc21 +O=C1c2c(C(=O)N1)cccc2c1ccc2Oc3c(N(C)c2c1)cccc3 +CN1c2ccccc2Oc2ccc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc21 +CN1c2ccccc2Oc2ccc(-c3cnc4ncccc4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3cncc4c3[nH]c3ccncc34)cc21 +CN1c2ccccc2Oc2ccc(-c3nc4ccccc4o3)cc21 +CN1c2ccccc2Oc2ccc(-c3nccnc3-c3ccccc3)cc21 +CN1c2ccccc2Oc2ccc(-c3ncon3)cc21 +CN1c2ccccc2Oc2ccc(-n3ccc4nc5ccoc5nc43)cc21 +CN1c2ccccc2Oc2cccc(-c3(C)-c4ccccc4-c4ccccc4-3)c21 +CN1c2ccccc2Oc2cccc(-c3=cC(=O)c4ccccc4C3=O)c21 +CN1c2ccccc2Oc2cccc(-c3c4[nH]cnc4nc4nc[nH]c34)c21 +CN1c2ccccc2Oc2cccc(-c3cc4cc5occc5cc4o3)c21 +CN1c2ccccc2Oc2cccc(-c3cc4nc5ccoc5nc4[nH]3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc(-c4ccccn4)nc3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(c3)C(=O)c=cC4=O)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(cnc5ccccc54)c3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4ccc5cccnc5c4n3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4nn[nH]c4c3)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4ncc5ccccc5c34)c21 +CN1c2ccccc2Oc2cccc(-c3cnc4c(ccc5cccnc54)c3)c21 +CN1c2ccccc2Oc2cccc(-c3cnc4cccnc4c3)c21 +CN1c2ccccc2Oc2cccc(-c3nc4cc5ncoc5nc4o3)c21 +CN1c2ccccc2Oc2cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c21 +CN1c2ccccc2Oc2cccc(-c3ncc(C#N)cn3)c21 +CN1c2ccccc2Oc2cccc(-c3nccc4c3[nH]c3ccccc34)c21 +CN1c2ccccc2Oc2cccc(-n3ccc4cnccc43)c21 +CN1c2ccccc2Oc2cccc(-n3cnc4nc5nc[nH]c5cc43)c21 +Fc1c(c(c(c(F)c1N1c2c(CCc3c1cccc3)cccc2)F)F)F +Fc1c(F)c(F)c(-c2ccc3c(c2)c2ccccc2c2[nH]cnc32)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c(n2)sc2ncccc23)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c4c2CCCN4CCC3)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3ccoc3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3cc[nH]c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3oc4ccccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3[nH]c4cnccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c2oc2ncccc23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4ccccc4c4[nH]cnc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4nccnc4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4nc[nH]c4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4[nH]cnc4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3ccoc23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3ncc4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2ccn[nH]2)c(F)c1F +Fc1c(F)c(F)c(-c2cnc3sc4ccccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2cncc3c2[nH]c2ccccc23)c(F)c1F +Fc1c(F)c(F)c(-c2coc3cc4[nH]ccc4cc23)c(F)c1F +Fc1cc(-c2c3ccoc3cc3ccoc23)cc(F)c1F +Fc1cc(-c2ccc3sccc3c2)cc(F)c1F +Fc1cc(-c2ccc3[nH]nnc3c2)cc(F)c1F +Fc1cc(-c2cccc3[nH]c4cnccc4c23)cc(F)c1F +Fc1cc(-c2cccc3[nH]c4ncccc4c23)cc(F)c1F +Fc1cc(-c2cnc3ccccc3n2)cc(F)c1F +Fc1cc(-c2cnc3cccnc3c2)cc(F)c1F +Fc1cc(-c2csc3ccccc23)cc(F)c1F +Fc1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc(F)c1F +Fc1cc(-n2cnc3nc4nc[nH]c4nc32)cc(F)c1F +Fc1cc(-n2nnc3ccccc32)cc(F)c1F +Fc1ccc(-c2c3[nH]cnc3nc3nc[nH]c23)c(F)c1F +Fc1ccc(-c2cc3cc4occc4cc3o2)c(F)c1F +Fc1ccc(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c(F)c1F +Fc1ccc(-c2cccc3ncoc23)c(F)c1F +Fc1ccc(-c2cccnc2-c2ccccn2)c(F)c1F +Fc1ccc(-c2cncc3cc[nH]c23)c(F)c1F +Fc1ccc(-c2csc3ccccc23)c(F)c1F +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc5cc6cc[nH]c6cc5o4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc5nc6ccoc6nc5[nH]4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccc6c7ccccc7[nH]c6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccncc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(n4)oc4ccccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c6ccccc6c6[nH]cnc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5ncc6ccccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5oc6ccccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5oc6ncccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5[nH]c6ccncc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc(-c5cc6c7c(c5)CCCN7CCC6)c4)cc3)n2)cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5c4oc4ncccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5c6[nH]cnc6c6ccccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5ncc6ccccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5[nH]c6cnccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4csc5ccccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4c[nH]c5cc6occc6cc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4c[nH]c5nc6occc6nc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-n4c5ccccc5c5c6[nH]c7ccccc7c6ccc54)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c5ccoc5cc5ccoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c5ncoc5cc5ncoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5cc6cc[nH]c6cc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5ccccc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5ccccc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5nc6cc[nH]c6nc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c(c4)sc4ncccc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c(c4)[nH]c4[nH]c6ccccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c6ccccc6c6nc[nH]c6c5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5ncoc5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5c4[nH]c4ccncc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5cc[nH]c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5occc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5[nH]nnc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c[nH]c5nc6occc6nc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4nc5cc6scnc6cc5s4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4nccc5[nH]c6ccccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-n4c5ccccc5c5c6ccccc6[nH]c54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-n4c5ccccc5c5cnccc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3c4ccoc4cc4ccoc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3c4ncoc4cc4ncoc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4c5c(c3)CCCN5CCC4)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4nc5ccoc5nc4[nH]3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(c3)Oc3ccccc3O4)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(n3)sc3ccccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(n3)sc3ncccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c5ccccc5c5[nH]cnc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4ccoc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4[nH]nnc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4c5ccccc5c5nccnc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4scnc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccccc3N(c3ccccc3)c3ccccc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccnc4sc5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cnc4sc5ncccc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cn[nH]c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-n3ccc4ccccc43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cc5ccccc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cc5nc6ccoc6nc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5c(c4)c4ccccc4c4[nH]cnc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5c(c4)[nH]c4c5ccc5[nH]c6ccccc6c54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5ocnc5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5[nH]c6ccc7c8ccccc8[nH]c7c6c5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5c6ccccc6c6nccnc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5ccoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5occc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5[nH]c6ccc7c8ccccc8[nH]c7c6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccccc4-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccnc5sc6ncccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccnnc4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4coc5cc6ccoc6cc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4nccc5[nH]c6ccncc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-n4nnc5ccccc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3c4ncsc4cc4ncsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3cnccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c5ccccc5c5[nH]cnc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4ocnc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4[nH]c5cnccc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4c3sc3ncccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4ccsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4cnc5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4ncsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4sccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5ccncc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4[nH]ccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccnc4sc5ncccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cnc4c5ccccc5c5ccccc5c4n3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3coc4cc5[nH]ccc5cc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3nc4c5ccccc5c5ccccc5c4[nH]3)n2)cc1 +Fc1ccc(-n2ccc3cnccc32)c(F)c1F +N#Cc1cc(-c2c3[nH]ccc3cc3ccoc23)cc(C#N)c1C#N +N#Cc1cc(-c2cc(=O)c3ccccc3[nH]2)cc(C#N)c1C#N +N#Cc1cc(-c2cc3ccccc3o2)cc(C#N)c1C#N +N#Cc1cc(-c2ccc(F)c(F)c2F)cc(C#N)c1C#N +N#Cc1c(c(C#N)cc(c1)c1ccc2CCc3c(cccc3)Nc2c1)C#N +N#Cc1cc(-c2ccc3c(c2)oc2ccccc23)cc(C#N)c1C#N +N#Cc1cc(-c2ccc3c(cnc4ccccc43)c2)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3c4nc[nH]c4c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3c4[nH]cnc4c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3ocnc23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3sccc23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3[nH]ccc(=O)c23)cc(C#N)c1C#N +N#Cc1cc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)cc(C#N)c1C#N +N#Cc1cc(-c2cncc3[nH]c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2coc3cc4ccoc4cc23)cc(C#N)c1C#N +N#Cc1cc(-c2csc3ccccc23)cc(C#N)c1C#N +N#Cc1cc(-c2c[nH]c3nc4occc4nc23)cc(C#N)c1C#N +N#Cc1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc(C#N)c1C#N +N#Cc1cc(-n2ccc(=O)c3ccccc32)cc(C#N)c1C#N +N#Cc1cc(C#N)c(-c2cc3cc4cc[nH]c4cc3o2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cc3cc4occc4cc3o2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3c(n2)sc2ccccc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3ncoc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3oc4ncccc4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3sccc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3scnc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc(N(c3ccccc3)c3ccccc3)c2)c(C#N)c1 +N#Cc1cc(C#N)cc(C#N)c1c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1cc(C#N)c(-c2cccc3c4ccccc4c4nc[nH]c4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3ccoc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3ccsc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3oc4ccccc4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3occc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3[nH]ccc(=O)c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cnc3sc4ccccc4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2c[nH]c3ccccc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2nc3cc4scnc4cc3s2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2nccc3[nH]c4ccncc4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-n2nnc3ccccc32)c(C#N)c1 +N#Cc1cc(C#N)cc(-c2c3cc[nH]c3cc3occc23)c1 +N#Cc1cc(C#N)cc(-c2c3ncsc3cc3ncsc23)c1 +N#Cc1cc(C#N)cc(-c2cc3c(cn2)[nH]c2ccccc23)c1 +N#Cc1cc(C#N)cc(-c2cc3nc4cc[nH]c4nc3o2)c1 +N#Cc1cc(C#N)cc(-c2cc3[nH]c4ccccc4c3cn2)c1 +N#Cc1cc(C#N)cc(-c2ccc(N)cc2)c1 +N#Cc1cc(C#N)cc(-c2ccc3c(=O)c4ccccc4[nH]c3c2)c1 +N#Cc1cc(C#N)cc(-c2ccc3cnc4ccccc4c3c2)c1 +N#Cc1cc(C#N)cc(-c2ccc3[nH]nnc3c2)c1 +N#Cc1cc(C#N)cc(-c2cccc(N)c2)c1 +N#Cc1cc(C#N)cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3c4[nH]cnc4c4ccccc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3ccoc23)c1 +N#Cc1cc(C#N)cc(-c2cccc3cnc4ccccc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3ncoc23)c1 +N#Cc1cc(C#N)cc(-c2cccc3occc23)c1 +N#Cc1cc(C#N)cc(-c2cc[nH]n2)c1 +N#Cc1cc(C#N)cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +N#Cc1cc(C#N)cc(-c2cncc3c2[nH]c2ccncc23)c1 +N#Cc1cc(C#N)cc(-n2c3ccccc3c3cnccc32)c1 +N#Cc1ccc(-c2c3ccoc3cc3ccoc23)cc1C#N +N#Cc1ccc(-c2c3ncoc3cc3ncoc23)c(C#N)c1 +N#Cc1ccc(-c2c3[nH]ccc3cc3ccoc23)c(C#N)c1 +N#Cc1ccc(-c2c3[nH]ccc3cc3ccoc23)c(C#N)c1C#N +N#Cc1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)cc1 +N#Cc1ccc(-c2cc3cc4ccoc4cc3[nH]2)cc1C#N +N#Cc1ccc(-c2cc3cc4cc[nH]c4cc3o2)c(C#N)c1C#N +N#Cc1ccc(-c2cc3ccccc3o2)c(C#N)c1 +N#Cc1ccc(-c2cc3ccccc3[nH]2)cc1 +N#Cc1ccc(-c2cc3nc4ccoc4nc3[nH]2)c(C#N)c1C#N +N#Cc1ccc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cc3[nH]c4ccccc4c3cn2)cc1 +N#Cc1ccc(-c2ccc(F)c(F)c2F)cc1 +N#Cc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1C#N +N#Cc1ccc(-c2ccc(N)cc2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(=O)cc[nH]c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(=O)cc[nH]c3c2)cc1C#N +N#Cc1ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +N#Cc1ccc(-c2ccc3c(c2)oc2ccccc23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(c2)Oc2ccccc2O3)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(c2)oc2ncccc23)cc1 +N#Cc1ccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cc1 +N#Cc1ccc(-c2ccc3c(cnc4ccccc43)c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(cnc4ccccc43)c2)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(n2)oc2ccccc23)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(n2)sc2ccccc23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(n2)sc2ccccc23)cc1 +N#Cc1ccc(-c2ccc3c(n2)sc2ncccc23)c(C#N)c1 +N#Cc1ccc(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)cc1 +N#Cc1ccc(-c2ccc3cnc4ccccc4c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3oc4ccccc4c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3occc3c2)cc1 +N#Cc1ccc(-c2ccc3[nH]c4ccc5c6ccccc6[nH]c5c4c3c2)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)cc1C#N +N#Cc1ccc(-c2ccc3[nH]ccc3c2)c(C#N)c1C#N +N#Cc1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2)cc1C#N +N#Cc1ccc(-c2cccc(N)c2)c(C#N)c1C#N +N#Cc1ccc(-c2cccc(N)c2)cc1C#N +N#Cc1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)cc1C#N +N#Cc1ccc(-c2cccc3c(=O)cc[nH]c23)c(C#N)c1C#N +N#Cc1c(c(C#N)c(cc1)c1c2c(Sc3c(cccc3)N2)ccc1)C#N +N#Cc1ccc(cc1)c1c2c(ccc1)Nc1c(S2)cccc1 +N#Cc1ccc(-c2cccc3c2cnc2ccccc23)cc1 +N#Cc1ccc(-c2cccc3c2oc2ccccc23)c(C#N)c1 +N#Cc1ccc(-c2cccc3c2sc2ncccc23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2cnccc23)cc1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)cc1 +N#Cc1ccc(-c2cccc3c4nc[nH]c4c4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c4nc[nH]c4c4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3c4[nH]cnc4c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3cnc4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3ncc4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3ncoc23)cc1 +N#Cc1ccc(-c2cccc3oc4ncccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3oc4ncccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3ocnc23)cc1 +N#Cc1ccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3[nH]c4cnccc4c23)cc1 +N#Cc1ccc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)cc1C#N +N#Cc1ccc(-c2cccc3[nH]ccc23)cc1C#N +N#Cc1ccc(-c2cccc3[nH]nnc23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3[nH]nnc23)cc1C#N +N#Cc1ccc(-c2ccccc2N)c(C#N)c1 +N#Cc1ccc(-c2ccnc3sc4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2ccnnc2)c(C#N)c1 +N#Cc1ccc(-c2cncc3[nH]c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cn[nH]c2)c(C#N)c1 +N#Cc1ccc(-c2coc3cc4ccoc4cc23)cc1 +N#Cc1ccc(-c2coc3cc4[nH]ccc4cc23)c(C#N)c1C#N +N#Cc1ccc(-c2coc3ccccc23)cc1C#N +N#Cc1ccc(-c2c[nH]c3cc4occc4cc23)c(C#N)c1C#N +N#Cc1ccc(-c2c[nH]c3ccccc23)c(C#N)c1 +N#Cc1ccc(-c2c[nH]c3ccccc23)cc1C#N +N#Cc1ccc(-c2nc3cc4scnc4cc3s2)c(C#N)c1C#N +N#Cc1ccc(-c2nc3ccccc3c3ccccc23)c(C#N)c1 +N#Cc1ccc(-c2nc3ccccc3s2)c(C#N)c1 +N#Cc1ccc(-c2nc3ccccc3s2)c(C#N)c1C#N +N#Cc1ccc(-c2nc3ccccc3s2)cc1C#N +N#Cc1ccc(-c2nc3nc4nc[nH]c4nc3[nH]2)c(C#N)c1 +N#Cc1ccc(-c2nccc3c2[nH]c2ccccc23)c(C#N)c1 +N#Cc1ccc(-n2c3ccccc3c3c4ccccc4[nH]c32)cc1 +N#Cc1ccc(-n2c3ccccc3c3c4ccccc4[nH]c32)cc1C#N +N#Cc1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c(C#N)c1C#N +N#Cc1ccc(-n2c3ccccc3c3ccncc32)cc1C#N +N#Cc1ccc(-n2ccc(=O)c3ccccc32)cc1C#N +N#Cc1ccc(-n2ccc3cc4ccoc4cc32)cc1 +N#Cc1ccc(-n2ccc3cc4ccoc4cc32)cc1C#N +N#Cc1ccc(-n2cnc3c4ccccc4c4ccccc4c32)cc1C#N +N#Cc1cccc(c1)N1c2c(Sc3c1cccc3)cccc2 +N#Cc1cccc(-c2c3cc[nH]c3cc3occc23)c1 +N#Cc1cccc(-c2c3cc[nH]c3cc3occc23)c1C#N +N#Cc1cccc(-c2c3ncsc3cc3ncsc23)c1 +N#Cc1cccc(-c2cc3cc4ccoc4cc3[nH]2)c1C#N +N#Cc1cccc(-c2cc3cc4occc4cc3o2)c1C#N +N#Cc1cccc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c1 +N#Cc1cccc(-c2cc3[nH]c4ccncc4c3cn2)c1 +N#Cc1cccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1 +N#Cc1cccc(-c2ccc3c(=O)cc[nH]c3c2)c1C#N +N#Cc1cccc(-c2ccc3c(c2)c2ccccc2c2[nH]cnc32)c1C#N +N#Cc1c(C#N)c(ccc1)c1cc2CCc3c(cccc3)Nc2cc1 +N#Cc1cccc(-c2ccc3c(c2)oc2ncccc23)c1 +N#Cc1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +N#Cc1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1C#N +N#Cc1cccc(-c2ccc3nn[nH]c3c2)c1C#N +N#Cc1cccc(-c2ccc3occc3c2)c1 +N#Cc1cccc(-c2ccc3occc3c2)c1C#N +N#Cc1cccc(-c2ccc3[nH]nnc3c2)c1C#N +N#Cc1cccc(-c2cccc(N)c2)c1C#N +N#Cc1cccc(-c2cccc3c(=O)cc[nH]c23)c1 +N#Cc1cccc(c1)c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1cccc(c1)c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1c(C#N)c(ccc1)c1c2c(ccc1)Nc1c(S2)cccc1 +N#Cc1cccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c1 +N#Cc1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +N#Cc1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1C#N +N#Cc1cccc(-c2cccc3ccoc23)c1 +N#Cc1cccc(-c2cccc3ocnc23)c1 +N#Cc1cccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c1C#N +N#Cc1cccc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c1 +N#Cc1cccc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)c1C#N +N#Cc1cccc(-c2ccnc3sc4ccccc4c23)c1 +N#Cc1cccc(-c2ccnc3sc4ccccc4c23)c1C#N +N#Cc1cccc(-c2ccnc3sc4ncccc4c23)c1 +N#Cc1cccc(-c2ccnc3sc4ncccc4c23)c1C#N +N#Cc1cccc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1C#N +N#Cc1cccc(-c2cn[nH]c2)c1C#N +N#Cc1cccc(-c2c[nH]c3ccccc23)c1 +N#Cc1cccc(-c2nc3cc4scnc4cc3s2)c1 +N#Cc1cccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c1 +N#Cc1cccc(-n2ccc3ccccc32)c1C#N +N#Cc1cccc(C#N)c1-c1c2[nH]ccc2cc2ccoc12 +N#Cc1cccc(C#N)c1-c1cc2nc3cc[nH]c3nc2o1 +N#Cc1cccc(C#N)c1-c1ccc2c(c1)oc1ncccc12 +N#Cc1cccc(C#N)c1-c1ccc2ncc3ccccc3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2occc2c1 +N#Cc1cccc(C#N)c1-c1ccc2sc3ncccc3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3ccc4c5ccccc5[nH]c4c3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3ccncc3c2c1 +N#Cc1cccc(C#N)c1c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1cccc(C#N)c1-c1cccc2c3ccccc3c3nccnc3c12 +N#Cc1cccc(C#N)c1-c1cccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c12 +N#Cc1cccc(C#N)c1-c1cccc2[nH]ccc(=O)c12 +N#Cc1cccc(C#N)c1-c1ccccc1N(c1ccccc1)c1ccccc1 +N#Cc1cccc(C#N)c1-c1cn[nH]c1 +N#Cc1cccc(C#N)c1-c1nc2ccccc2s1 +N#Cc1cccc(C#N)c1-n1c2ccccc2c(=O)c2ccccc21 +N#Cc1cccc(C#N)c1-n1c2ccccc2c2c3ccccc3[nH]c21 +N#Cc1cccc(C#N)c1-n1c2ccccc2c2cnccc21 +N#Cc1cccc(C#N)c1-n1c2ccncc2c2cnccc21 +N#Cc1cccc(C#N)c1-n1ccc2nc3ccoc3nc21 +N#Cc1cccc(C#N)c1-n1cnc2nc3nc[nH]c3nc21 +N#Cc1ccccc1-c1c(-c2ccccc2)cc2c3c1CCCN3CCC2 +N#Cc1ccccc1-c1cc(F)c(F)c(F)c1 +N#Cc1ccccc1-c1cc2cc3cc[nH]c3cc2o1 +N#Cc1ccccc1-c1cc2[nH]c3ccncc3c2cn1 +N#Cc1ccccc1-c1ccc2c(c1)c1ccccc1c1[nH]cnc21 +N#Cc1ccccc1-c1ccc2scnc2c1 +N#Cc1ccccc1c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1ccccc1-c1cccc2c3ccccc3c3nc[nH]c3c12 +N#Cc1ccccc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +N#Cc1ccccc1-c1cccc2c3[nH]cnc3c3ccccc3c12 +N#Cc1ccccc1-c1cccc2ncc3ccccc3c12 +N#Cc1ccccc1-c1cccc2[nH]c3[nH]c4ccccc4c3c12 +N#Cc1ccccc1-c1cccc2[nH]nnc12 +N#Cc1ccccc1-c1cc[nH]n1 +N#Cc1ccccc1-c1coc2cc3[nH]ccc3cc12 +N#Cc1ccccc1-c1c[nH]c2cc3occc3cc12 +N#Cc1ccccc1-n1c2ccccc2c2cnccc21 +N#Cc1cnc(-c2cc3ccccc3o2)nc1 +N#Cc1cnc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)nc1 +c1(C#N)cnc(nc1)c1cc2c(Sc3c(cccc3)N2)cc1 +N#Cc1cnc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)nc1 +N#Cc1cnc(-c2ccc3c(c2)Oc2ccccc2O3)nc1 +N#Cc1cnc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)nc1 +N#Cc1cnc(-c2ccc3sc4ncccc4c3c2)nc1 +N#Cc1cnc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)nc1 +N#Cc1cnc(-c2ccc3[nH]nnc3c2)nc1 +N#Cc1cnc(-c2cccc3c2sc2ncccc23)nc1 +N#Cc1cnc(-c2cccc3c2[nH]c2cnccc23)nc1 +N#Cc1cnc(-c2cccc3c4ccccc4c4[nH]cnc4c23)nc1 +N#Cc1cnc(-c2cccc3c4nccnc4c4ccccc4c23)nc1 +N#Cc1cnc(-c2cccc3ccsc23)nc1 +N#Cc1cnc(-c2cccc3ncc4ccccc4c23)nc1 +N#Cc1cnc(-c2cccc3ncsc23)nc1 +N#Cc1cnc(-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)nc1 +N#Cc1cnc(-c2cnc3sc4ncccc4c3c2)nc1 +N#Cc1cnc(-c2c[nH]c3nc4occc4nc23)nc1 +N#Cc1cnc(-c2nc3ccccc3c3ccccc23)nc1 +N#Cc1cnc(-n2c3ccccc3c3ccncc32)nc1 +N#Cc1cnc(-n2ccc(=O)c3ccccc32)nc1 +N#Cc1cncnc1-c1cc2[nH]c3ccccc3c2cn1 +N#Cc1cncnc1-c1ccc2c(c1)Oc1ccccc1O2 +N#Cc1cncnc1-c1ccc2ncoc2c1 +N#Cc1cncnc1-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +N#Cc1cncnc1-c1cccc(N(c2ccccc2)c2ccccc2)c1 +c1(C#N)cncnc1c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1cncnc1-c1cccc2c1oc1ccccc12 +N#Cc1cncnc1-c1cccc2c1oc1ncccc12 +N#Cc1cncnc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +N#Cc1cncnc1-c1cccc2sccc12 +N#Cc1cncnc1-c1cccc2scnc12 +N#Cc1cncnc1-c1cccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c12 +N#Cc1cncnc1-c1cccc2[nH]c3ccncc3c12 +N#Cc1cncnc1-c1cccc2[nH]nnc12 +N#Cc1cncnc1-c1nc2c3ccccc3c3ccccc3c2[nH]1 +N#Cc1cncnc1-c1nc2ccccc2o1 +N#Cc1cncnc1-c1nccc2c1[nH]c1ccccc12 +N#Cc1cncnc1-c1nccc2[nH]c3ccncc3c12 +N#Cc1cncnc1-n1c2ccccc2c2ccc3[nH]c4ccccc4c3c21 +N#Cc1cncnc1-n1c2ccncc2c2cnccc21 +N#Cc1cncnc1-n1ccc2nc3ccoc3nc21 +Nc1ccc(-c2c3ncoc3nc3ocnc23)cc1 +Nc1ccc(-c2ccc3c(c2)-s(=O)(=O)-c2ccccc2-3)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc(N)cc1 +Nc1ccc(-c2ccc3ncccc3n2)cc1 +Nc1ccc(-c2ccc3[nH]nnc3c2)cc1 +Nc1ccc(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)cc1 +Nc1ccc(-c2cccc(C(=O)C(F)(F)F)c2)cc1 +Nc1ccc(-c2cccc3ocnc23)cc1 +Nc1ccc(-c2cccc3[nH]c4ncccc4c23)cc1 +Nc1ccc(-c2cnc3nccnc3n2)cc1 +Nc1ccc(-c2nc3ccccc3o2)cc1 +Nc1ccc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc1 +Nc1ccc(-n2c3ccncc3c3cnccc32)cc1 +Nc1ccc(-n2cnc3cc4nc[nH]c4cc32)cc1 +Nc1ccc(-n2cnc3nc4nc[nH]c4cc32)cc1 +Nc1cccc(-c2c(F)c(F)c(F)c(F)c2F)c1 +Nc1cccc(-c2c3ccoc3cc3ccoc23)c1 +Nc1cccc(-c2cc(=O)c3ccccc3[nH]2)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cccc(N)c1 +Nc1cccc(-c2ccc3c4c2Oc2ccccc2B4c2ccccc2O3)c1 +Nc1cccc(-c2ccc3cccnc3n2)c1 +Nc1cccc(-c2ccc3ncc4ccccc4c3c2)c1 +Nc1cccc(-c2ccc3ocnc3c2)c1 +Nc1cccc(-c2cccc(-c3ccccn3)n2)c1 +Nc1cccc(-c2cccc3sccc23)c1 +Nc1cccc(-c2ccon2)c1 +Nc1cccc(-c2cncc3cc[nH]c23)c1 +Nc1cccc(-c2coc3cc4ccoc4cc23)c1 +Nc1cccc(-c2nc3ccccc3o2)c1 +Nc1cccc(-n2ccc3nc4ccoc4nc32)c1 +Nc1ccccc1-c1c2[nH]cnc2nc2nc[nH]c12 +Nc1ccccc1-c1cc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)ccc1F +Nc1ccccc1-c1cc2c(cn1)[nH]c1ccccc12 +Nc1ccccc1-c1ccc(-c2ccccn2)nc1 +Nc1ccccc1-c1ccc(-c2cnccn2)cc1 +Nc1ccccc1-c1ccc2c(c1)B1c3ccccc3Oc3cccc(c31)O2 +Nc1ccccc1-c1ccc2c(c1)sc1ccccc12 +Nc1ccccc1-c1ccc2nccnc2c1 +Nc1ccccc1-c1ccc2sc3ccccc3c2c1 +Nc1ccccc1-c1ccc2[nH]c3cnccc3c2c1 +Nc1ccccc1-c1ccc2[nH]ccc(=O)c2c1 +Nc1ccccc1-c1cccc2nccnc12 +Nc1ccccc1-c1cccc2sc3ccccc3c12 +Nc1ccccc1-c1cccc2[nH]ccc(=O)c12 +Nc1ccccc1-c1ccccc1C(=O)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +Nc1ccccc1-c1cncc2[nH]c3ccccc3c12 +Nc1ccccc1-c1nc2cc3ncoc3nc2o1 +Nc1ccccc1-c1nc2ccccc2o1 +Nc1ccccc1-n1c2ccccc2c2ccncc21 +Nc1ccccc1-n1ccc2cnccc21 +O=C(c1ccc(-c2c(-c3ccccc3)cc3c4c2CCCN4CCC3)cc1)C(F)(F)F +O=C(c1ccc(-c2c3ccoc3cc3ccoc23)cc1)C(F)(F)F +O=C(c1ccc(-c2c3cc[nH]c3cc3occc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cc3[nH]c4ccccc4c3cn2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2cc3[nH]c4ccncc4c3cn2)cc1)C(F)(F)F +O=C(c1ccc(-c2ccc3c(=O)cc[nH]c3c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(cc1)c1cc2c(Sc3c(cccc3)N2)cc1)C(F)(F)F +O=C(c1ccc(-c2ccc3c(c2)c2ccccc2c2nccnc32)cc1)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +O=C(c1ccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2ccc3c(n2)sc2ccccc23)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2ccc3oc4ccccc4c3c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c(=O)cc[nH]c23)cc1)C(F)(F)F +O=C(c1ccc(cc1)c1c2CCc3c(cccc3)Nc2ccc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c2sc2ncccc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3ccoc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3oc4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3[nH]c4cnccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2ccnc3oc4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2ccnnc2)cc1)C(F)(F)F +O=C(c1ccc(-c2cnc3oc4ccccc4c3c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cnc3sc4ccccc4c3c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cncc3[nH]c4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2cn[nH]c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2c[nH]c(=O)[nH]2)cc1)C(F)(F)F +O=C(c1ccc(-c2c[nH]c3ccccc3c2=O)cc1)C(F)(F)F +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2c3ncsc3cc3ncsc23)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3c2cnc2ccccc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3cc[nH]c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3cnc4ccccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3nn[nH]c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3sc4ncccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3[nH]c4cnccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2coc3cc4ccoc4cc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2coc3ccccc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2c[nH]c3nc4occc4nc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2nc3ccccc3o2)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-n2ccc3nc4ccoc4nc32)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)N1c2c(Sc3c1cccc3)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)N1c2c(CCc3c1cccc3)cccc2 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3c(cn2)[nH]c2ccccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3ccccc3[nH]2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3nc4ccoc4nc3[nH]2)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)Oc2ccccc2O3)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2cnccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(n2)oc2ccccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3ccsc3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3occc3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c2oc2ncccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c4ccccc4c4nccnc4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3cc[nH]c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3ncsc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3nn[nH]c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3[nH]nnc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2c[nH]c3nc4occc4nc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2nc3ccccc3s2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2nccc3[nH]c4ccccc4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-n2c3ccccc3c3cnccc32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-n2ccc3cc4ccoc4cc32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c2cc[nH]c2cc2occc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c2ncoc2cc2ncoc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc(-c2cc3c4c(c2)CCCN4CCC3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1ccc2c(Sc3c(cccc3)N2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)ncc1ccccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)oc1ncccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)sc1ncccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)[nH]c1ccc3c4ccccc4[nH]c3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(n1)oc1ccccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c3ccccc3c3nc[nH]c3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2cnc3ccccc3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2ncoc2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cccc2c3nccnc3c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cccc2ccoc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccccc1N(c1ccccc1)c1ccccc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccnnc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cnc2oc3ccccc3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cncc2[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c[nH]c2cc3occc3cc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1nccc2[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1nccc2[nH]c3ccncc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1c2ccccc2c2c3[nH]c4ccccc4c3ccc21 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1c2ccccc2c2cnccc21 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1ccc2ccccc21 +O=C(c1ccc(-c2nc3ccccc3c3ccccc23)cc1)C(F)(F)F +O=C(c1ccc(-c2nccc3[nH]c4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)cc1)C(F)(F)F +O=C(c1ccc(-n2nnc3ccccc32)cc1)C(F)(F)F +O=C(c1cccc(-c2c3ncoc3cc3ncoc23)c1)C(F)(F)F +O=C(c1cccc(-c2c3ncsc3cc3ncsc23)c1)C(F)(F)F +O=C(c1cccc(-c2cc(=O)c3ccccc3[nH]2)c1)C(F)(F)F +O=C(c1cccc(-c2cc3cc4cc[nH]c4cc3o2)c1)C(F)(F)F +O=C(c1cccc(-c2cc3[nH]c4ccncc4c3cn2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cc2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3c(c2)Oc2ccccc2O3)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3c4c2CCCN4CCC3)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3ncc4ccccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3oc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3sc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3c(=O)cc[nH]c23)c1)C(F)(F)F +O=C(c1cccc(c1)c1c2c(CCc3c(cccc3)N2)ccc1)C(F)(F)F +O=C(c1cccc(-c2cccc3ccsc23)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3nn[nH]c23)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3oc4ncccc4c23)c1)C(F)(F)F +O=C(c1cccc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)c1)C(F)(F)F +O=C(c1cccc(-c2cnc3sc4ccccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2cnc3sc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2coc3cc4[nH]ccc4cc23)c1)C(F)(F)F +O=C(c1cccc(-c2csc3ccccc23)c1)C(F)(F)F +O=C(c1cccc(-c2c[nH]c3ccccc23)c1)C(F)(F)F +O=C(c1cccc(-c2c[nH]c3nc4occc4nc23)c1)C(F)(F)F +O=C(c1cccc(-c2nc3c4ccccc4c4ccccc4c3[nH]2)c1)C(F)(F)F +O=C(c1cccc(-n2c3ccccc3c(=O)c3ccccc32)c1)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)N3c4c(CCc5c3cccc5)cccc4)cc2)ccccc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cc5c(cn4)[nH]c4ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)ncc4ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)Oc4ccccc4O5)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)[nH]c4[nH]c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5ncoc5c4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5oc6ccccc6c5c4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4sc4ncccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4[nH]c4ccncc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c6ccccc6c6[nH]cnc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c6nccnc6c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5ccsc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5cnc6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5sc6ncccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5scnc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5[nH]c6ccccc6c(=O)c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cc[nH]n4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cncc5[nH]c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4coc5cc6[nH]ccc6cc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4coc5ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-n4c5ccccc5c5ccncc54)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-n4ccc(=O)c5ccccc54)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c(-c3ccccc3)cc3c4c2CCCN4CCC3)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c3ncsc3cc3ncsc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc(F)c(F)c2F)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(c2)c2ccccc2c2nccnc32)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(c2)oc2ncccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(n2)sc2ncccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3nn[nH]c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3[nH]c4ccncc4c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3[nH]nnc3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3c4[nH]cnc4c4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3cnc4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3sc4ncccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccnc3oc4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cn[nH]c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2coc3cc4[nH]ccc4cc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c[nH]c(=O)[nH]2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2nc3c4ccccc4c4ccccc4c3[nH]2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2nc3cc4ocnc4cc3o2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-n2ccc3cc4ccoc4cc32)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cc2c3ccccc3[nH]c2c2c1[nH]c1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2c(=O)cc[nH]c2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2c(n1)sc1ncccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2occc2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2sc3ncccc3c2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2[nH]ccc2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc(N(c2ccccc2)c2ccccc2)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2c3c(Sc4c(cccc4)N3)ccc2)ccccc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1cnc1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1Oc1ccccc1O2 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1oc1ncccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c3[nH]cnc3c3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2cnc3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2scnc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2[nH]c3cnccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccccc1-c1cc2c3c(c1)CCCN3CCC2 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cnc2c3ccccc3c3ccccc3c2n1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cncc2c1[nH]c1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1coc2cc3ccoc3cc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1coc2ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1c[nH]c2ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1nc2cc3ocnc3cc2o1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1nc2cc3scnc3cc2s1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-n1ccc2cc3ccoc3cc21 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-n1cnc2c3ccccc3c3ccccc3c21 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4cc5cc[nH]c5cc4o3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4cc5occc5cc4o3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3nccnc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)ncc3ccccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3ccncc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4[nH]ccc4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3ncc3ccccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3ccncc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3cnccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3[nH]c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c5nccnc5c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4ccsc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4nn[nH]c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4ocnc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5ccccc5c(=O)c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5cnccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccnn3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccnc4oc5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccn[nH]3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cnc4sc5ccccc5c4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cnc4sc5ncccc5c4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3coc4cc5[nH]ccc5cc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3c[nH]c(=O)[nH]3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3nccc4[nH]c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c(=O)c4ccccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c4cnccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccncc4c4cnccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3ccc(=O)c4ccccc43)n2)cc1 +O=C(c1ccccc1-c1c(-c2ccccc2)cc2c3c1CCCN3CCC2)C(F)(F)F +O=C(c1ccccc1-c1cc(=O)c2ccccc2[nH]1)C(F)(F)F +O=C(c1ccccc1-c1cc2nc3cc[nH]c3nc2o1)C(F)(F)F +O=C(c1ccccc1c1cc2c(Sc3c(cccc3)N2)cc1)C(F)(F)F +O=C(c1ccccc1c1cc2CCc3c(cccc3)Nc2cc1)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)oc1ncccc12)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccccc3c21)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1ccc2occc2c1)C(F)(F)F +O=C(c1ccccc1-c1cccc2c(=O)cc[nH]c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2c1[nH]c1c2ccc2[nH]c3ccccc3c21)C(F)(F)F +O=C(c1ccccc1-c1cccc2c3nccnc3c3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2ccoc12)C(F)(F)F +O=C(c1ccccc1-c1cccc2oc3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2[nH]c3ccc4c5ccccc5[nH]c4c3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2[nH]c3ccncc3c12)C(F)(F)F +O=C(c1ccccc1-c1ccccc1N(c1ccccc1)c1ccccc1)C(F)(F)F +O=C(c1ccccc1-c1coc2nc3[nH]ccc3nc12)C(F)(F)F +O=C(c1ccccc1-c1c[nH]c2cc3occc3cc12)C(F)(F)F +O=C(c1ccccc1-c1c[nH]c2ccccc2c1=O)C(F)(F)F +O=C(c1ccccc1-c1nc2c3ccccc3c3ccccc3c2[nH]1)C(F)(F)F +O=C(c1ccccc1-c1nccc2[nH]c3ccncc3c12)C(F)(F)F +O=C(c1ccccc1-n1c2ccccc2c(=O)c2ccccc21)C(F)(F)F +O=C(c1ccccc1-n1ccc(=O)c2ccccc21)C(F)(F)F +O=C(c1ccccc1-n1cnc2nc3nc[nH]c3nc21)C(F)(F)F +O=c1c(-c2c3[nH]ccc3cc3ccoc23)c[nH]c2ccccc12 +O=c1c(-c2c3[nH]cnc3nc3nc[nH]c23)c[nH]c2ccccc12 +O=c1c(-c2cc(F)c(F)c(F)c2)c[nH]c2ccccc12 +O=c1c(-c2cc3c4c(c2)CCCN4CCC3)c[nH]c2ccccc12 +O=c1c(-c2cc3ccccc3o2)c[nH]c2ccccc12 +O=c1c(-c2cc3ccccc3s2)c[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]cc1c1cc2CCc3c(cccc3)Nc2cc1 +O=c1c(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c[nH]c2ccccc12 +O=c1c(-c2ccc3c(c2)[nH]c2ncccc23)c[nH]c2ccccc12 +O=c1c(-c2ccc3c4c2CCCN4CCC3)c[nH]c2ccccc12 +O=c1c(-c2ccc3cc[nH]c3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3oc4ccccc4c3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3sccc3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c[nH]c2ccccc12 +O=c1c(-c2cccc(-c3cnccn3)c2)c[nH]c2ccccc12 +O=c1c(-c2cccc3c(=O)cc[nH]c23)c[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]cc1c1c2c(CCc3c(cccc3)N2)ccc1 +O=c1c(-c2cccc3c2ncc2ccccc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2Oc2ccccc2O3)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2sc2ncccc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c[nH]c2ccccc12 +O=c1c(-c2cccc3ccoc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3cnc4ccccc4c23)c[nH]c2ccccc12 +O=c1c(-c2ccnc(-c3ccccn3)c2)c[nH]c2ccccc12 +O=c1c(-c2ccnc3ncccc23)c[nH]c2ccccc12 +O=c1c(-c2ccnc3[nH]c4ccccc4c23)c[nH]c2ccccc12 +O=c1c(-c2ccno2)c[nH]c2ccccc12 +O=c1c(-c2cnc3cccnc3c2)c[nH]c2ccccc12 +O=c1c(-c2c[nH]c3ccccc23)c[nH]c2ccccc12 +O=c1c(-c2nc3cc4scnc4cc3s2)c[nH]c2ccccc12 +O=c1c(-c2nc3ccccc3s2)c[nH]c2ccccc12 +O=c1c(-c2nc3nc4nc[nH]c4cc3[nH]2)c[nH]c2ccccc12 +O=c1c(-c2nccc3[nH]c4ccncc4c23)c[nH]c2ccccc12 +O=c1c(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c[nH]c2ccccc12 +O=c1c(-n2c3ccncc3c3cnccc32)c[nH]c2ccccc12 +O=c1c(-n2ccc3cnccc32)c[nH]c2ccccc12 +O=c1c(-n2cc[nH]c2=O)c[nH]c2ccccc12 +O=c1c(-n2cnc3nc4nc[nH]c4nc32)c[nH]c2ccccc12 +O=C1c2c(C(=O)N1c1c3c(cc4c1cco4)[nH]cc3)cccc2 +O=C1c2c(C(=O)N1c1ncc3c4c(cccc4)[nH]c3c1)cccc2 +O=C1c2c(C(=O)N1c1nc3oc4c(c3cc1)cccc4)cccc2 +O=C1c2c(C(=O)N1c1ccc3c(c4c5c(cccc5)[nH]c4[nH]3)c1)cccc2 +O=C1c2c(C(=O)N1c1c3c4c(cccc4)cnc3ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3c(oc4ncccc34)ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3c(ccc1)[nH]c1c3ccnc1)cccc2 +O=C1c2c(C(=O)N1c1nc3c4c(c5c(c3nc1)cccc5)cccc4)cccc2 +O=C1c2c(C(=O)N1c1c3c4c(cccc4)[nH]c3cnc1)cccc2 +O=C1c2c(C(=O)N1n1c3c(c(=O)c4c1cccc4)cccc3)cccc2 +O=C1c2c(C(=O)N1n1c3c(c4c1ccnc4)cncc3)cccc2 +O=c1c2ccccc2n(-c2c3ccoc3cc3ccoc23)c2ccccc12 +O=c1c2ccccc2n(-c2cc(F)ccc2-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3c(c2)B2c4ccccc4Oc4cccc(c42)O3)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3ccsc3c2)c2ccccc12 +O=c1c2ccccc2n(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)c2ccccc12 +O=c1c2ccccc2n(-c2cccc3c2[nH]c2ncccc23)c2ccccc12 +O=c1c2ccccc2n(-c2ccnc3c2ccc2cccnc23)c2ccccc12 +O=c1c2ccccc2n(-c2cncc3cc[nH]c23)c2ccccc12 +O=c1c2ccccc2n(-c2cncc3[nH]c4ccccc4c23)c2ccccc12 +O=c1c2ccccc2n(-c2c[nH]c3ccncc23)c2ccccc12 +O=c1c2ccccc2n(-c2nccs2)c2ccccc12 +O=c1c2ccccc2n(-n2c3ccccc3c3cccnc32)c2ccccc12 +O=c1c2ccccc2n(-n2c3ccccc3c3ccncc32)c2ccccc12 +O=c1c2ccccc2n(-n2cnc3cc4nc[nH]c4cc32)c2ccccc12 +O=c1c2ccccc2[nH]c2c(-c3c(F)c(F)c(F)c(F)c3F)cccc12 +O=c1c2ccccc2[nH]c2c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cc4nc5ccoc5nc4[nH]3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc(-c4ccccn4)n3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc4c3[nH]c3cnccc34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3ccnc(-c4ccccn4)c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cnc4[nH]c5ccccc5c4c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cncs3)cccc12 +O=c1c2ccccc2[nH]c2c(-n3nnc4ccccc43)cccc12 +O=c1c2ccccc2[nH]c2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cc4cccnc4c4ncccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc(-c4cnccn4)cc3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(cnc5ccccc54)c3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cccc4ocnc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3csc4ccccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4cc5ncoc5nc4o3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4ccccc4o3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nccs3)ccc12 +O=c1c2ccccc2[nH]c2cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +O=c1c2ccccc2[nH]c2ccc(-c3c4ccoc4cc4ccoc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cc(F)ccc3-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cc4c(cn3)[nH]c3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc(-c4ccccn4)nc3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4ccsc4c3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4[nH]nnc4c3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4c(=O)cc[nH]c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4c3ncc3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4ccsc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4ncc5ccccc5c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccnc4c3ccc3cccnc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccnc4[nH]c5ccccc5c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cnc(-c4ccccc4)cn3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3nc4nc5ocnc5nc4o3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3nccc4c3[nH]c3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-n3ccc4cnccc43)cc12 +O=c1c2ccccc2[nH]c2cccc(-c3cc4cccnc4c4ncccc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4ccsc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4ncoc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4nn[nH]c4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4sc5ccccc5c4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cccc4c3-c3ccccc3-s-4(=O)=O)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cccc4ncc5ccccc5c34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccnc4cccnc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cnc4c(ccc5cccnc54)c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cnc4ncccc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cncs3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3nccc4[nH]ccc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ncno3)c12 +O=c1c2ccccc2[nH]c2cccc(-n3c4ccccc4c4ccncc43)c12 +O=C1c2c(C(=O)C(=C1)N1c3c(Sc4c1cccc4)cccc3)cccc2 +O=C1c=c(-c2c3ccoc3cc3ccoc23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(cc3c1cco3)[nH]cc2 +O=C1C=C(C(=O)N1)c1c2c(ocn2)cc2ncoc12 +O=C1C=C(C(=O)N1)c1cc(=O)c2c(cccc2)[nH]1 +O=C1c=c(-c2cc3c(cn2)[nH]c2ccccc23)C(=O)c2ccccc21 +O=C1c=c(-c2cc3cc4occc4cc3o2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1oc2c(c1)cccc2 +O=C1C=C(C(=O)N1)c1ncc2c(c1)[nH]c1c2cncc1 +O=C1C=C(C(=O)N1)c1ccc(N(c2ccccc2)c2ccccc2)cc1 +O=C1C=C(C(=O)N1)c1ccc2CCc3c(cccc3)Nc2c1 +O=C1c2c(C(=O)C(=C1)c1ccc3CCc4c(cccc4)Nc3c1)cccc2 +O=C1c2c(C(=O)C(=C1)c1ccc3c(Sc4c(cccc4)N3)c1)cccc2 +O=C1C=C(C(=O)N1)c1ccc2c(oc3ncccc23)c1 +O=C1C=C(C(=O)N1)c1cc2c(c3c4c(c5c(cccc5)[nH]4)ccc3[nH]2)cc1 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]c1c2cncc1 +O=C1c=c(-c2ccc3c4c2CCCN4CCC3)C(=O)c2ccccc21 +O=C1c=c(-c2ccc3c4ccccc4c4nccnc4c3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c3c(c4c(nc[nH]4)c2c1)cccc3 +O=C1C=C(C(=O)N1)c1ccc2c(scc2)c1 +O=C1c=c(-c2ccc3ccsc3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]cc2 +O=C1c=c(-c2ccc3ncsc3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]nn2 +O=C1C=C(C(=O)N1)c1cc2c(occ2)cc1 +O=C1c=c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)C(=O)c2ccccc21 +O=C1c=c(-c2ccc3[nH]nnc3c2)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3c2cnc2ccccc23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(c3c4c(cccc4)[nH]c3[nH]2)ccc1 +O=C1c=c(-c2cccc3c4ccccc4c4nc[nH]c4c23)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3c4ccccc4c4[nH]cnc4c23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(nn[nH]2)ccc1 +O=C1c=c(-c2cccc3ocnc23)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c(c2cc3c4c(CCCN4CCC3)c2)cccc1 +O=C1c=c(-c2cnc3sc4ccccc4c3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c3c(cccc3)[nH]c2cnc1 +O=C1c=c(-c2c[nH]c(=O)[nH]2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(cccc2)[nH]c1 +O=C1c=c(-c2nc3cc4ocnc4cc3o2)C(=O)c2ccccc21 +O=C1c=c(-n2c3ccccc3c(=O)c3ccccc32)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)n1c2c(c3c1ccnc3)cccc2 +O=C1C=C(C(=O)N1)n1c2c(nc1)c1c(c3c2cccc3)cccc1 +O=C1C=CC(=O)N1c1c2c(c3c(c4c(cccc4)[nH]3)c1)c1c(cccc1)[nH]2 +O=C1C=CC(=O)N1c1sc2c(c1)cccc2 +O=C1C=CC(=O)N1c1cc2c(cccc2)[nH]1 +O=C1C=CC(=O)N1c1oc2c(nc3c(n2)[nH]cc3)c1 +O=C1C=CC(=O)N1c1c2c3c(cccc3)[nH]c2c2c(c1)[nH]c1c2cccc1 +O=C1C=CC(=O)N1c1ncc2c(c1)[nH]c1c2cncc1 +O=C1C=CC(=O)N1c1ccc(c2cc3c4c(CCCN4CCC3)c2)cc1 +O=C1C=CC(=O)N1c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1C=CC(=O)N1c1cc2c(c3c4c(cccc4)[nH]c3[nH]2)cc1 +O=C1C=CC(=O)N1c1ccc2c3c(c4c(c2c1)nccn4)cccc3 +O=C1C=CC(=O)N1c1cc2c(occ2)cc1 +O=C1C=CC(=O)N1c1cc2ncsc2cc1 +O=C1C=CC(=O)N1c1c2ncc3c(c2ccc1)cccc3 +O=C1C=CC(=O)N1c1c2c(c3c(c4c(cc3)[nH]c3c4cccc3)[nH]2)ccc1 +O=C1C=CC(=O)N1c1c2c(nco2)ccc1 +O=C1C=CC(=O)N1c1c2c3c(cccc3)[nH]c2cnc1 +O=C1C=CC(=O)N1c1c2c(oc1)cc1c(occ1)c2 +O=C1C=CC(=O)N1c1c2c(oc1)cccc2 +O=C1C=CC(=O)N1c1c2c(cc3c(c2)cco3)[nH]c1 +O=C1C=CC(=O)N1c1c2c(c3c(n1)cccc3)cccc2 +O=C1C=CC(=O)N1n1c2c(c3c1ccnc3)cccc2 +O=C1C=CC(=O)N1n1c2c(nc3c(occ3)n2)cc1 +O=C1C=CC(=O)N1n1c2c(nn1)cccc2 +O=C1c2c(C(=O)C=C1)cccc2N1c2c(CCc3c1cccc3)cccc2 +O=C1c=cC(=O)c2c1cccc2-c1c2ncoc2cc2ncoc12 +O=C1c=cC(=O)c2c1cccc2-c1c2[nH]ccc2cc2ccoc12 +O=C1c=cC(=O)c2c1cccc2-c1cc2nc3ccoc3nc2[nH]1 +O=C1c=cC(=O)c2c1cccc2-c1ccc(F)c(F)c1F +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2c(c1)ncc1ccccc12 +O=C1c=cC(=O)c2c1cccc2-c1ccc2c(n1)sc1ncccc12 +O=C1c=cC(=O)c2c1cccc2-c1ccc2cnc3ccccc3c2c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2ncc3ccccc3c2c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +O=C1c2c(C(=O)C=C1)cccc2c1c2c(Sc3c(cccc3)N2)ccc1 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c1[nH]c1c2ccc2[nH]c3ccccc3c21 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c1[nH]c1cnccc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c3ccccc3c3nccnc3c12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2ccoc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2occc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2[nH]c3ccccc3c(=O)c12 +O=C1c=cC(=O)c2c1cccc2-c1ccccc1N(c1ccccc1)c1ccccc1 +O=C1c=cC(=O)c2c1cccc2-c1nc2c3ccccc3c3ccccc3c2[nH]1 +O=C1c=cC(=O)c2c1cccc2-c1nccc2[nH]c3ccncc3c12 +O=C1c=cC(=O)c2c1cccc2-n1c2ccncc2c2cnccc21 +O=C1c=cC(=O)c2c1cccc2-n1ccc(=O)c2ccccc21 +O=C1c=cC(=O)c2cc(-c3cc4cc5ccoc5cc4[nH]3)ccc21 +O=C1c=cC(=O)c2cc(-c3cc4cc5occc5cc4o3)ccc21 +O=C1c=cC(=O)c2cc(-c3cc4nc5cc[nH]c5nc4o3)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(c3)Oc3ccccc3O4)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(c3)sc3ncccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(n3)sc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4[nH]ccc(=O)c4c3)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3cnc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3ncc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3oc3ncccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3[nH]c3ccncc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5ccccc5c(=O)c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5ccncc5c34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccccc3-c3cc4c5c(c3)CCCN5CCC4)ccc21 +O=C1c=cC(=O)c2cc(-c3cnc4sc5ccccc5c4c3)ccc21 +O=C1c=cC(=O)c2cc(-n3cc[nH]c3=O)ccc21 +O=C1c=cC(=O)c2cc(-n3nnc4ccccc43)ccc21 +O=c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)[nH]c2ccccc12 +O=c1cc(-c2cc3cccnc3c3ncccc23)[nH]c2ccccc12 +O=c1cc(-c2cc3[nH]c4ccncc4c3cn2)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)-s(=O)(=O)-c2ccccc2-3)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)c2ccccc2c2nccnc32)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]c(c1)c1cc2CCc3c(cccc3)Nc2cc1 +O=c1cc(-c2ccc3c(n2)sc2ccccc23)[nH]c2ccccc12 +O=c1cc(-c2ccc3c4c2CCCN4CCC3)[nH]c2ccccc12 +O=c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3cc[nH]c3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3scnc3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3[nH]c4ccncc4c3c2)[nH]c2ccccc12 +O=c1cc(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4ccccc4c4nccnc4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4ccccc4c4nc[nH]c4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4nccnc4c4ccccc4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3[nH]c4ccccc4c(=O)c23)[nH]c2ccccc12 +O=c1cc(-c2ccnc3c2ccc2cccnc23)[nH]c2ccccc12 +O=c1cc(-c2ccnc3cccnc23)[nH]c2ccccc12 +O=c1cc(-c2ccon2)[nH]c2ccccc12 +O=c1cc(-c2cc[nH]n2)[nH]c2ccccc12 +O=c1cc(-c2cnc3cccnc3c2)[nH]c2ccccc12 +O=c1cc(-c2c[nH]c3ccncc23)[nH]c2ccccc12 +O=c1cc(-c2nc3nc4ocnc4nc3o2)[nH]c2ccccc12 +O=c1cc(-n2c3ccccc3c3ccncc32)[nH]c2ccccc12 +O=c1cc(-n2ccc(=O)c3ccccc32)[nH]c2ccccc12 +O=c1cc(-n2cnc3nc4nc[nH]c4nc32)[nH]c2ccccc12 +O=C1c2c(C(=O)N1)cccc2c1ncc2c(c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)cccc2c1c(F)c(c(F)cc1)F +O=C1c2c(C(=O)N1)cccc2c1ccc2c(sc3ncccc23)c1 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c1)[nH]c1c2ccc2c1c1c(cccc1)[nH]2 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c(=O)c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)cccc2c1cccc(N(c2ccccc2)c2ccccc2)c1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)Nc1c(S2)cccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(c3c(c4c2nccn4)cccc3)ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c3nc[nH]c3c3c(c2ccc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1c2ncsc2ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)[nH]c1c2cncc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(=O)cc[nH]c2ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c3c(sc2ncc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1nc2c3c(c4c(c2nc1)cccc4)cccc3 +O=C1c2c(C(=O)N1)cccc2c1cnc2c(c3c(nccc3)s2)c1 +O=C1c2c(C(=O)N1)cccc2c1oc2c(n1)cc1c(nco1)c2 +O=C1c2c(C(=O)N1)cccc2n1c2c(c(=O)c3c1cccc3)cccc2 +O=C1c2c(C(=O)N1)cccc2n1c2c(c3c1c1c(cc3)[nH]c3c1cccc3)cccc2 +O=C1c2c(C(=O)N1)cccc2n1c2c(nc1)c1c(c3c2cccc3)cccc1 +O=C1c2c(C(=O)N1)cccc2n1c2c(nc1)nc1nc[nH]c1n2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc3c(c2)cco3)[nH]1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c3c(cccc3)[nH]c2c2c(c1)[nH]c1c2cccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(oc3ncccc23)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)[nH]c1c2ccc2c1c1c(cccc1)[nH]2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(c3c4c(c5c(cccc5)[nH]4)ccc3[nH]2)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)cnc1c2cccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2ncoc2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(occ2)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c(=O)c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc1)[nH]cc2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c(=O)c3c(cccc3)[nH]2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(Sc3c(cccc3)N2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(nco2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccc1)[nH]c1c2c2c(cccc2)[nH]1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccnnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c3c(cccc3)[nH]2)cnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c3c(cccc3)[nH]c2cnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(oc1)cc1c(cc[nH]1)c2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(cc3c(c2)cco3)[nH]c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccn1)[nH]c1c2cncc1 +O=C1c2c(C(=O)N1)ccc(c2)n1c2c(c3c(cccc3)[nH]2)c2c1cccc2 +O=c1ccn(-c2c3ncsc3cc3ncsc23)c2ccccc12 +O=c1ccn(-c2cc3ccccc3o2)c2ccccc12 +O=c1ccn(-c2cc3cccnc3c3ncccc23)c2ccccc12 +O=c1ccn(-c2cc3[nH]ccc3cn2)c2ccccc12 +O=c1ccn(-c2ccc(F)c(F)c2F)c2ccccc12 +O=c1ccn(-c2ccc3c(c2)-c2ccccc2-s-3(=O)=O)c2ccccc12 +O=c1ccn(-c2ccc3c(c2)B2c4ccccc4Oc4cccc(c42)O3)c2ccccc12 +O=c1c2c(n(cc1)c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +O=c1ccn(-c2ccc3c(c2)[nH]c2ncccc23)c2ccccc12 +O=c1ccn(-c2ccc3[nH]ccc3c2)c2ccccc12 +O=c1ccn(-c2cccc3ccsc23)c2ccccc12 +O=c1ccn(-c2cccc3cnc4ccccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3oc4ccccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3oc4ncccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3ocnc23)c2ccccc12 +O=c1ccn(-c2cccc3scnc23)c2ccccc12 +O=c1ccn(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c2ccccc12 +O=c1ccn(-c2cccc3[nH]c4ccncc4c23)c2ccccc12 +O=c1ccn(-c2ccno2)c2ccccc12 +O=c1ccn(-c2cnc3sc4ncccc4c3c2)c2ccccc12 +O=c1ccn(-c2cncc(-c3ccccc3)n2)c2ccccc12 +O=c1ccn(-c2cncc3[nH]c4ccccc4c23)c2ccccc12 +O=c1ccn(-c2c[nH]c3cc4occc4cc23)c2ccccc12 +O=c1ccn(-c2c[nH]c3ccncc23)c2ccccc12 +O=c1cc[nH]c2c(-c3c4ccoc4cc4ccoc34)cccc12 +O=c1cc[nH]c2c(-c3c4[nH]ccc4cc4ccoc34)cccc12 +O=c1cc[nH]c2c(-c3cc4ccccc4o3)cccc12 +O=c1cc[nH]c2c(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc12 +O=c1cc[nH]c2c(-c3ccc(F)c(F)c3F)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)ncc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)oc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4ccsc4c3)cccc12 +O=c1cc[nH]c2c(-c3ccc4sccc4c3)cccc12 +O=c1cc[nH]c2c(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)cccc12 +O=c1cc[nH]c2c(-c3cccc4c3oc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3cccc4ncoc34)cccc12 +O=c1cc[nH]c2c(-c3cccc4nn[nH]c34)cccc12 +O=c1cc[nH]c2c(-c3cccc4oc5ccccc5c34)cccc12 +O=c1cc[nH]c2c(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)cccc12 +O=c1cc[nH]c2c(-c3ccccc3-c3cnccn3)cccc12 +O=c1cc[nH]c2c(-c3ccnc4cccnc34)cccc12 +O=c1cc[nH]c2c(-c3ccnc4sc5ccccc5c34)cccc12 +O=c1cc[nH]c2c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +O=c1cc[nH]c2c(-c3cnc4ncccc4c3)cccc12 +O=c1cc[nH]c2c(-c3cnc4nccnc4n3)cccc12 +O=c1cc[nH]c2c(-c3cscn3)cccc12 +O=c1cc[nH]c2c(-c3c[nH]c4ccncc34)cccc12 +O=c1cc[nH]c2c(-c3nc4nc5nc[nH]c5cc4[nH]3)cccc12 +O=c1cc[nH]c2c(-n3c4ccccc4c4ccncc43)cccc12 +O=c1cc[nH]c2c(-n3ccc4ccccc43)cccc12 +O=c1cc[nH]c2cc(-c3c(-c4ccccc4)cc4c5c3CCCN5CCC4)ccc12 +O=c1cc[nH]c2cc(-c3c4ncoc4cc4ncoc34)ccc12 +O=c1cc[nH]c2cc(-c3c4ncsc4cc4ncsc34)ccc12 +O=c1cc[nH]c2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +O=c1cc[nH]c2cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +O=c1cc[nH]c2cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3cc4cc5cc[nH]c5cc4o3)ccc12 +O=c1cc[nH]c2cc(-c3cc4ccccc4o3)ccc12 +O=c1cc[nH]c2cc(-c3cc4ccccc4s3)ccc12 +O=c1cc[nH]c2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc12 +O=c1cc[nH]c2cc(-c3ccc(-c4ccccn4)nc3)ccc12 +O=c1cc[nH]c2cc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)ccc12 +O=c1c2c(cc(cc2)c2ccc3CCc4c(cccc4)Nc3c2)[nH]cc1 +O=c1cc[nH]c2cc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)Oc3ccccc3O4)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)sc3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(n3)sc3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4ncsc4c3)ccc12 +O=c1cc[nH]c2cc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)ccc12 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)-[nH]-c4ccccc4CC5)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)c4ccccc4c4[nH]cnc54)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccc6c7ccccc7[nH]c6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5cc[nH]c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5[nH]c6ccc7c8ccccc8[nH]c7c6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4cnc4ccccc45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4[nH]c4cnccc45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c6nc[nH]c6c6ccccc6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cnc5oc6ccccc6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cnc5sc6ccccc6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5cc6ocnc6cc5o4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5cc6scnc6cc5s4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nccc5[nH]c6ccccc6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5cc6occc6cc5o4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5ccccc5o4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5[nH]c6ccccc6c5c5[nH]c6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5sc6ncccc6c5c4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c4-[nH]-c4ccccc4CC5)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c6ccccc6c6nccnc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5cnc6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5oc6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5occc45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5[nH]c6ccncc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5[nH]c6[nH]c7ccccc7c6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4c[nH]c5cc6occc6cc45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4nc5nc6nc[nH]c6nc5[nH]4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4ccc5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4nnc5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cc4nc5ccoc5nc4[nH]3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)-s-c3ccccc3-[nH]-4)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)-[nH]-c3ccccc3-s-4)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)[nH]c3cnccc34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c5ccccc5c5nc[nH]c5c4c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4sc5ncccc5c4c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cccc(N(c4ccccc4)c4ccccc4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cccc4c5[nH]cnc5c5ccccc5c34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3c[nH]c4cc5occc5cc34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3cnc4nc5nc[nH]c5nc43)n2)cc1 +CC1(C)c2cc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)ccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccccc1 +CC1(C)c2cc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)ccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4)c3cc21 +CC1(C)c2cc3c(cc2-[nH]-c2c(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)cccc21)c1ccccc1n3-c1ccccc1 +CC1(C)c2cc3c(cc2-[nH]-c2cccc(-c4ccc5cccc6c5c4-c4nc5cc(C#N)c(C#N)cc5nc4-6)c21)c1ccccc1n3-c1ccccc1 +CC1(C)c2ccccc2-c2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc21 +CC1(C)c2ccccc2-c2cc(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)ccc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc21 +CC1(C)c2ccccc2-n(-c2cc3c4c(cccc4c2)-c2nc4cc(C#N)c(C#N)cc4nc2-3)-c2cc3c4ccccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-n(-c2ccc3cccc4c3c2-c2nc3cc(C#N)c(C#N)cc3nc2-4)-c2ccccc21 +CC1(C)c2ccccc2-[nH]-c2c(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)cccc21 +CC1(C)c2ccccc2-[nH]-c2c(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cccc21 +CC1(C)c2ccccc2-[nH]-c2c1cc1c(c2-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2ccccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2c(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)cccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2c(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2cc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)ccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccc(-c2ccc3c4c(cccc24)-c2nc4cc(C#N)c(C#N)cc4nc2-3)cc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 +CC1(C)c2ccccc2-[nH]-c2cc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)ccc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4c(-c5cc6c7c(cccc7c5)-c5nc7cc(C#N)c(C#N)cc7nc5-6)cccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4c(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)cccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4cc(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)ccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4cccc(-c5c(C#N)c(C#N)cc6nc7c(nc56)-c5cccc6cccc-7c56)c4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4-c4cc5c6c(cccc6c4)-c4nc6cc(C#N)c(C#N)cc6nc4-5)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4-c4ccc5cccc6c5c4-c4nc5cc(C#N)c(C#N)cc5nc4-6)c3cc21 +CC1(C)c2ccccc2-[nH]-c2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc21 +Cc1-c2ccccc2-[nH]-c2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc2-1 +Cc1-c2ccccc2-[nH]-c2cccc(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)c2-1 +Cc1c(C)c(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2c(c1C)c1ccccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cccc1n2C +Cc1cccc2c1[nH]c1c(C)cc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c5c(cccc35)-c3nc5cc(C#N)c(C#N)cc5nc3-4)c12 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc2ccccc12 +CN(C)c1cc2ccccc2cc1-c1ccc2c3c(cccc13)-c1nc3cc(C#N)c(C#N)cc3nc1-2 +CN(C)c1cc2ccccc2cc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c1 +CN(C)c1cc2ccccc2cc1-c1ccccc1-c1nc(-c2ccccc2)nc(-c2ccccc2)n1 +CN(C)c1ccc2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc2c1 +CN1c2ccccc2N(C)c2c(-c3ccc4c5c(cccc35)-c3nc5cc(C#N)c(C#N)cc5nc3-4)cccc21 +CN1c2ccccc2N(C)c2cc(-c3cc4c5c(cccc5c3)-c3nc5cc(C#N)c(C#N)cc5nc3-4)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)ccc21 +CN1c2ccccc2Oc2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc21 +N#Cc1cc2nc3c(nc2c(-c2c(-c4ccccc4)cc4c5c2CCCN5CCC4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cc4nc5cc[nH]c5nc4o2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c(c2)[nH]c2ccc5c6ccccc6[nH]c5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c(c2)[nH]c2ccncc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c5c2CCCN5CCC4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4ccoc4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4ocnc4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4[nH]c5[nH]c6ccccc6c5c4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c(=O)cc[nH]c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2ncc2ccccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2[nH]c2cnccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c5ccccc5c5nc[nH]c5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4cnc5ccccc5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4occc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4[nH]c5ccccc5c(=O)c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4[nH]ccc(=O)c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2nccc4c2[nH]c2ccccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2nccc4[nH]c5ccncc5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2-c4ccccc4CCc4ccccc4-2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2ccc(=O)c4ccccc42)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2ccc4nc5ccoc5nc42)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4c5ccccc5[nH]c4c4c2[nH]c2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4ccccc4o2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4nc5ccoc5nc4[nH]2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc(N)cc2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)CCc2ccccc2-[nH]-4)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)oc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)[nH]c2ccncc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(n2)oc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(n2)sc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4ccoc4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4occc4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c(=O)cc[nH]c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c5ccccc5c5nc[nH]c5c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c5nccnc5c5ccccc5c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4ccsc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4[nH]ccc(=O)c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2coc4ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2c[nH]c(=O)[nH]2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-n2c4ccccc4c4c5ccccc5[nH]c42)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-n2cc[nH]c2=O)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cc(F)c(F)c(F)c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cc4nc5cc[nH]c5nc4o2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4c(c2)CCc2ccccc2-[nH]-4)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4ocnc4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4[nH]ccc(=O)c4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4c2cnc2ccccc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4c2Oc2ccccc2O4)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4ncsc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4sccc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-n2c4ccccc4c4ccc5[nH]c6ccccc6c5c42)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-n2ccc4nc5ccoc5nc42)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2c4ccoc4cc4ccoc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cc4cc5cc[nH]c5cc4o2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)c2ccccc2c2nc[nH]c42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)c2ccccc2c2[nH]cnc42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)[nH]c2cnccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(n2)sc2ncccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4oc5ccccc5c4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4ocnc4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4[nH]c5[nH]c6ccccc6c5c4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc(N(c4ccccc4)c4ccccc4)c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c(=O)cc[nH]c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c2[nH]c2c4ccc4[nH]c5ccccc5c42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c2[nH]c2cnccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4oc5ccccc5c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4scnc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccnc4sc5ncccc5c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccnnc2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cncc4c2[nH]c2ccccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2nc4cc5scnc5cc4s2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2nc4ccccc4s2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2-c4ccccc4-s-c4ccccc4-2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2ccc4cc5ccoc5cc42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2cnc4c5ccccc5c5ccccc5c42)c2cccc-3c12 +O=c1c2ccccc2n(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2ccccc12 +O=c1c2ccccc2[nH]c2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc12 +O=c1ccn(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2ccccc12 +c1ccc(-c2cncc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +c1ccc(-c2cncc(-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccccc4C4(c5ccccc5)c5ccccc5-[nH]-c5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)n2)cc1 +c1ccc(-c2nccnc2-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1 +c1ccc(-c2nccnc2-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cc5cc6occc6cc5o4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cc5[nH]ccc5cn4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccc5c(c4)Oc4cccc6c4B5c4ccccc4O6)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccnc5c4ccc4cccnc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccnc5[nH]c6ccccc6c45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cnc5nccnc5n4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cncc5[nH]c6ccccc6c45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4csc5ccccc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4c[nH]c5nc6occc6nc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4nc5ccccc5c5ccccc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4nc5nc6nc[nH]c6nc5[nH]4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4c5[nH]cnc5nc5nc[nH]c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cc5c(cn4)[nH]c4ccccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cc5cc6occc6cc5o4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5c(c4)sc4ccccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5ncccc5n4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5sc6ccccc6c5c4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccc5c4[nH]c4ncccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccc5sc6ccccc6c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccnc4-c4ccccn4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccnc5[nH]c6ccccc6c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cnc5nccnc5n4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cnoc4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-n4nnc5ccccc54)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ncno3)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ncon3)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cc5nc6cc[nH]c6nc5o4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cc5[nH]ccc5cn4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccc5ncoc5c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccc5[nH]c6cnccc6c5c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cccc(-c5cnccn5)c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cccc5nn[nH]c45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccnc5c4ccc4cccnc45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cncc5c4[nH]c4ccncc45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4c5ccccc5c5cccnc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4ccc5nc6ccoc6nc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4cnc5cc6nc[nH]c6cc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4c5[nH]cnc5cc5nc[nH]c45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cc5nc6ccoc6nc5[nH]4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cccc(-c5cnccn5)c4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cccc5c4[nH]c4ncccc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccccc4-c4cnccn4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccnc5[nH]c6ccccc6c45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccon4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cncs4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4coc5cc6ccoc6cc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4coc5nc6[nH]ccc6nc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-n4cnc5nc6nc[nH]c6nc54)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4c5[nH]cnc5cc5nc[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4c5[nH]cnc5nc5nc[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cc5ccccc5s4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc(-c5cnccn5)cc4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5ccc6cccnc6c5n4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5nn[nH]c5c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5[nH]nnc5c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc(-c5cnccn5)c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5c4Oc4cccc6c4B5c4ccccc4O6)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5c4[nH]c4ncccc45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5nn[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5[nH]c6ncccc6c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5[nH]nnc45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cnc5c(ccc6cccnc65)c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cnc5ccccc5n4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5ccsc5c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5[nH]nnc5c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc(-c5cnccn5)c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5c4cnc4ccccc45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5c4sc4ccccc45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5[nH]c6cnccc6c45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccno4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cnc5c(ccc6cccnc65)c4)c32)cc1 +c1ccc(C2(c3ccccc3-c3cc4cnccc4[nH]3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4cccnc4n3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4nn[nH]c4c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3cccc4sc5ccccc5c34)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccnc(-c4ccccn4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nc4cc5ncoc5nc4o3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nc4ccccc4c4ccccc34)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nccs3)c3ccccc3-[nH]-c3ccccc32)cc1 +CC(=O)c1cccc(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)c1 +CC(=O)c1ccccc1-c1cccc2c1-[nH]-c1ccccc1C2(c1ccccc1)c1ccccc1 +Cc1-c2ccccc2-c2cc(-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)ccc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cc2-1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +N#Cc1cc(C#N)c(-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c(C#N)c1 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1ccc(-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1 +N#Cc1ccc(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)c(C#N)c1C#N +N#Cc1cccc(-c2ccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cc2)c1 +N#Cc1cccc(C#N)c1-c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1 +N#Cc1ccccc1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-[nH]-2 +N#Cc1cnc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)nc1 +O=C(c1ccc(-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1 +O=C(c1cccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3c2-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)c1)C(F)(F)F +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-[nH]-5)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4-[nH]-c4ccccc4C5(c4ccccc4)c4ccccc4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +O=C(c1ccccc1-c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1)C(F)(F)F +O=C(c1ccccc1-c1cccc2c1-[nH]-c1ccccc1C2(c1ccccc1)c1ccccc1)C(F)(F)F +O=C(c1ccccc1-n1-c2ccccc2C(c2ccccc2)(c2ccccc2)c2ccccc2-1)C(F)(F)F +O=c1c(-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c[nH]c2ccccc12 +O=C1c2ccccc2C(=O)n1-c1cccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c1 +O=C1c2ccccc2C(=O)n1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-[nH]-2 +O=C1c=c(-c2ccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cc2)C(=O)[nH]1 +O=C1c=c(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)C(=O)[nH]1 +O=c1cc(-c2cccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)c2)[nH]c2ccccc12 +O=c1cc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)[nH]c2ccccc12 +O=c1ccn(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c2ccccc12 +O=c1ccn(-c2cccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)c2)c2ccccc12 +O=c1ccn(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c2ccccc12 +O=c1cc[nH]c2c(-c3cccc4c3C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)cccc12 +O=c1cc[nH]c2c(-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cccc12 +O=C1[nH]C(=O)c2cc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)ccc21 +O=s1(=O)-c2ccccc2-c2c(-c3cccc4c3-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cccc2-1 +O=s1(=O)-c2ccccc2-c2cc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)ccc2-1 +O=s1(=O)-c2ccccc2-c2ccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cc2-1 +O=s1(=O)-c2ccccc2-c2cccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)c2-1 +O=s1(=O)-c2ccccc2-c2cccc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)c2-1 diff --git a/examples/tadf/TADF_f/config/f.yaml b/examples/tadf/TADF_f/config/f.yaml new file mode 100644 index 000000000..47a875684 --- /dev/null +++ b/examples/tadf/TADF_f/config/f.yaml @@ -0,0 +1,84 @@ +defaults: # + - ppsci_default # + - TRAIN: train_default # + - EVAL: eval_default # +# - INFER: infer_default # + - _self_ # + +hydra: + run: + # dynamic output directory according to running time and override name + dir: outputs_f/${now:%Y-%m-%d}/${now:%H-%M-%S}/${hydra.job.override_dirname} # + job: + name: ${mode} # name of logfile + chdir: false # keep current working directory unchanged + callbacks: + init_callback: # + _target_: ppsci.utils.callbacks.InitCallback # + sweep: + # output directory for multirun + dir: ${hydra.run.dir} + subdir: ./ + +# general settings +mode: eval # running mode: train/eval # +seed: 42 # +output_dir: ${hydra:run.dir} # +log_freq: 20 # +use_tbd: false # +VIV_DATA_PATH: "./f.dat" # +data_dir: "./f.dat" +sim_dir: "./smis.txt" + +# model settings +MODEL: # +# input_keys: tuple(x.keys()) # + output_keys: ["u"] # +# num_layers: None # +# hidden_size: +# - 587 +# - 256 # + activation: "relu" # + dropout: 0.5 + +# training settings +TRAIN: # + epochs: 200 # + iters_per_epoch: 20 # + save_freq: 100 # + eval_during_train: False # + batch_size: 8 # + learning_rate: 0.0001 + save_model_path: './f_model.pdparams' + weight_decay: 1e-5 + pretrained_model_path: null # + checkpoint_path: null # + k: 9 + i: 2 + +# evaluation settings +EVAL: + test_size: 0.1 + load_model_path: './f_pretrained.pdparams' + seed: 20 +# pretrained_model_path: null # +# batch_size: 32 # + +# inference settings +#INFER: # +# pretrained_model_path: "https://github.com/YfB1125/PaddleScience/blob/dev_model/TADF/f/output/checkpoints/latest.pdparams" # +# export_path: ./inference/viv # +# pdmodel_path: ${INFER.export_path}.pdmodel # +# pdiparams_path: ${INFER.export_path}.pdiparams # +# input_keys: ${MODEL.input_keys} # +# output_keys: ["u"] # +# device: cpu # +# engine: native # +# precision: fp32 # +# ir_optim: true # +# min_subgraph_size: 10 # +# gpu_mem: 4000 # +# gpu_id: 0 # +# max_batch_size: 64 # +# num_cpu_threads: 4 # +# batch_size: 16 # diff --git a/examples/tadf/TADF_f/f.dat b/examples/tadf/TADF_f/f.dat new file mode 100644 index 000000000..fefe7cfad --- /dev/null +++ b/examples/tadf/TADF_f/f.dat @@ -0,0 +1,5136 @@ +0.4353 +0.138 +0.2242 +0.2131 +0.0053 +0.0012 +0.0005 +0.282 +0.0001 +0.0027 +0.232 +0 +0.2864 +0.4516 +0.3835 +0.01 +0.201 +0.2153 +0 +0.3766 +0.0079 +0.0279 +0.0066 +0.0134 +0.0009 +0.0187 +0.0061 +0.007 +0.0118 +0.0152 +0.749 +0.7745 +0.149 +0.4347 +0.4174 +0.3619 +0.3283 +0.9525 +1.0409 +0.9721 +0.5637 +0.7599 +0.4983 +0.476 +0.5559 +0.741 +0.5599 +0.7991 +0.9505 +0.914 +0.8389 +0.76 +0.0328 +0.3153 +0.6455 +0.8935 +0.2721 +0.5452 +0.5576 +0.4397 +0.9226 +0.5118 +0.9088 +0.0312 +0.1588 +0.3632 +0.5404 +0.511 +0.0546 +0.9137 +0.4367 +0.8319 +0.2063 +0.6663 +0.6342 +0.0632 +0.0155 +0.4128 +0.0528 +0.5088 +0.0159 +0.0459 +0.0523 +0.0216 +0.027 +0.0082 +0.9618 +0.1758 +0.7487 +0.7659 +0.003 +0.004 +0.0036 +0.0068 +0.0297 +0.0849 +0.0993 +0.0279 +0.0056 +0.0453 +0.3122 +0.4991 +0.6682 +0.4755 +0.3978 +0.1997 +0.2883 +0.5267 +0.3122 +0.0062 +0.0989 +0.0252 +0.1866 +0.5387 +0.3857 +0.3025 +0.0148 +0.148 +0.5175 +0.0495 +0.0492 +0.1845 +0.0259 +0.3339 +0.2441 +0.2605 +0.2688 +0.0257 +0.0768 +0.4313 +0.2047 +0.2688 +0.0244 +0.2249 +0.0204 +0.0273 +0.0229 +0.0188 +0.0145 +0.0227 +0.433 +0.0358 +0.0207 +0.0224 +0.0165 +0.0006 +0.0995 +0.3596 +0.1086 +0.2048 +0.1659 +0.4199 +0.0884 +0.1169 +0.0169 +0.0768 +0.2379 +0.2414 +0.1766 +0.2566 +0.0066 +0.0018 +0.0353 +0.0118 +0.047 +0.058 +0.0764 +0.1076 +0.1722 +0.0574 +0.0604 +0.0169 +0.1443 +0.154 +0.1797 +0.0743 +0.123 +0.4451 +0.4019 +0.0657 +0.0884 +0.4065 +0.0185 +0.1963 +0.0023 +0.1778 +0.1415 +0.0398 +0.004 +0.3017 +0.2356 +0.1983 +0.0745 +0.1169 +0.001 +0.1508 +0.0111 +0.0393 +0.0401 +0.094 +0.1651 +0.0152 +0.4292 +0.1113 +0.3166 +0.6014 +0.166 +0.2689 +0.3701 +0.3095 +0.3898 +0.4704 +0.4328 +0.6325 +0.1626 +0.0033 +0.0005 +0.1842 +0.1092 +0.2787 +0.0399 +0.2743 +0.0046 +0.126 +0.158 +0.1824 +0.1914 +0.2295 +0.206 +0.154 +0.0854 +0.0885 +0.5478 +0.0051 +0.0219 +0.0171 +0.0066 +0.0251 +0.5865 +0.0093 +0.0521 +0.005 +0.0022 +0.0078 +0.0103 +0.0033 +0.3766 +0.116 +0.2974 +0.2038 +0.0346 +0.3083 +0.5442 +0.0176 +0.1879 +0.1212 +0.1011 +0.1647 +0.1974 +0.0264 +0.0588 +0.0456 +0.2147 +0.3718 +0.2246 +0.1882 +0.1897 +0.173 +0.1921 +0.3102 +0.1892 +0.0409 +0.037 +0.0463 +0.4533 +0.6661 +1.0001 +0.7949 +0.5588 +0.5319 +0.8328 +0.6843 +0.696 +0.0659 +0.4526 +0.383 +0.8929 +0.9681 +0.3212 +0.8139 +0.0011 +0.2067 +0.8588 +0.865 +0.9307 +0.656 +0.6644 +0.4555 +0.9453 +0.3412 +0.3252 +0.3821 +0.04 +0.2205 +0.2949 +0.1673 +0.5319 +0.5301 +0.3189 +0.1115 +0.113 +0.2011 +0.168 +0.3112 +0.247 +0.039 +0.0052 +0.0256 +0.0037 +0.0002 +0.0656 +0.0245 +0.0899 +0.0914 +0.1019 +0.0741 +0.1315 +0 +0.002 +0.0752 +0.0871 +0.0888 +0.0186 +0.3989 +0.142 +0.1498 +0.0816 +0.1171 +0.0025 +0.0118 +0.0001 +0.3218 +0.0875 +0.0061 +0.5296 +0.4058 +0.0216 +0.8716 +0.0001 +0.0011 +0.1336 +0.1297 +0.1801 +0.0031 +0.1203 +0.0382 +0.0017 +0.0184 +0.1847 +0.0481 +0.0136 +0 +0.0001 +0.7491 +0.0531 +0.0431 +0.0581 +0.0568 +0.6794 +0.0181 +0.267 +0.0794 +0.0348 +0.0414 +0.0457 +0.0577 +0.0279 +1.0809 +0.2067 +0.1195 +0.0231 +0 +0.5093 +0.2945 +0.1315 +0.1614 +0.4764 +0.1138 +0.0976 +0.0085 +1.3935 +0.7737 +0.6843 +0.1859 +0.0852 +0.2738 +0.0725 +0.0045 +0.238 +0.182 +0.2164 +0.8164 +0.3564 +0.2239 +0.0115 +0.1356 +0.5461 +0.5776 +1.1111 +1.098 +1.0397 +0.1586 +0.2288 +0.4699 +0.0118 +0.2976 +0.4181 +0.2825 +0.0704 +0.0002 +0.0291 +0.0639 +0.0393 +0.0505 +0.0233 +0.907 +1.0797 +1.0152 +1.0149 +0.3853 +0.7344 +0.0964 +0.0212 +0.0242 +0.0205 +0.0265 +0.8181 +0.134 +0.3367 +0.2364 +0.0001 +0.2591 +0.2384 +0.2237 +0.3101 +0.1693 +0.0795 +0.0546 +0.5428 +0.8949 +0.4484 +1.2043 +1.1833 +0.8074 +0.7585 +0.0728 +1.1048 +1.5393 +0.3478 +1.1737 +0.032 +1.2376 +0.0169 +0.2657 +0.3732 +0.322 +0.1845 +0.0749 +0.104 +0.1605 +0.1734 +0.0589 +0.0299 +0.9957 +0.0207 +0.6207 +0.8597 +0.6437 +0.0007 +0.1396 +0.0195 +0.0002 +0.0125 +0.2661 +0.0829 +0.2894 +0.0846 +0.2136 +0.004 +0.0053 +0.1378 +0.0481 +0.084 +0.1528 +0.0092 +0.1437 +0.0151 +0.0022 +0.0363 +0.0175 +0.0024 +0.0051 +0.0988 +0.4818 +0.0001 +0.4075 +0.7144 +0.1564 +0.9202 +0.43 +1.1735 +0.0178 +0.7261 +0.4231 +0.1252 +0.2599 +0.3708 +0.0135 +0.8536 +0.5187 +0.1312 +0.2621 +0.1156 +0.0057 +0.1066 +0.0505 +0.0549 +0.3089 +0.2467 +0.0139 +0.1603 +0.0307 +0.3742 +0.0256 +0.0045 +0.0111 +0.2667 +0.2503 +0.4122 +0.0638 +0.0188 +0.0027 +0.2325 +0.1255 +0.0266 +0.0427 +0.0027 +0.089 +0.1191 +0.0135 +0.0045 +0.0065 +0.026 +0.109 +0.0105 +0.0024 +0.0091 +0.0632 +0.0842 +0.645 +0.9779 +0.9644 +0.5171 +0.0856 +1.4474 +1.15 +1.344 +0.7076 +0.2432 +0.5119 +0.1538 +1.0532 +0.6985 +0.0017 +0.6651 +0.3727 +0.4773 +0.0088 +0.1743 +0.6177 +1.0064 +0.5544 +0.56 +0.7851 +0.6637 +0.5534 +0.578 +0.8305 +0.2507 +0.3448 +0.0066 +0.0784 +0.2566 +0.0075 +0.2396 +0.3916 +0.2024 +0.0102 +0.1887 +0.0287 +0.1527 +0.0131 +0.1012 +0.0401 +0.1516 +0.1472 +0.0454 +0.0506 +0.0164 +0.005 +0.0211 +0.305 +0.5753 +0.1922 +0.179 +0.2325 +0.019 +0.4416 +0.0735 +0.0676 +0.05 +0.0132 +0.0088 +0.0496 +0.0476 +0.0548 +0.1244 +0.0071 +0.0064 +0.7012 +0.4128 +0.459 +0.1814 +0.1246 +0.0392 +0.1303 +0.0143 +0.3573 +0.0155 +0.0596 +0.012 +0.2866 +0.0428 +0.071 +0.3109 +0.1665 +0.022 +0.0338 +0.051 +0.0033 +0.1365 +0.0029 +0.0025 +0.017 +1.1321 +0.9834 +0.6784 +0.5305 +0.2676 +0.0117 +0.1697 +0.32 +0.6479 +0.5518 +0.492 +0.0071 +0.0306 +0.0027 +0.0011 +0.0192 +0.0024 +0.0241 +0.0137 +0.0169 +0.011 +0.014 +0.0233 +0.0292 +0.027 +0.0003 +0.0123 +0.0361 +0.0722 +0.0468 +0.0128 +0.0013 +0.0049 +0.0852 +0.0506 +0.0052 +0.0738 +0.0709 +0.0903 +0.3525 +0.1686 +0.0002 +0.3438 +0.0001 +0.2625 +0.5383 +0.5889 +0.7287 +0.7814 +0.5537 +0.259 +0.5565 +0.4637 +0.0533 +0.0191 +0.0766 +0.1691 +0.0861 +0.1025 +0.046 +0.3759 +0.1116 +0.1154 +0.0215 +0.0001 +0.4479 +0.0717 +0.1219 +0.1468 +0.0348 +0.7675 +0.3911 +0.0293 +0.0177 +0.014 +0.0139 +0.0101 +0.0155 +0.1741 +0.1752 +0.0072 +0.0152 +0.0905 +0.0243 +0.0057 +0.1743 +0.0779 +0.1495 +0.0594 +0.0798 +0.0785 +0.2092 +0.183 +0.1372 +0.0078 +0.592 +0.4056 +0.1282 +0.1529 +0.2441 +0.001 +0.2469 +0.1379 +0.0396 +0.0043 +0.0076 +0.0351 +0.0107 +0.0056 +0.0184 +0.0317 +0.0084 +0.0162 +0.0009 +0.0059 +0.0708 +0.0015 +0.1124 +0 +0.0204 +0.051 +0.236 +0 +0.0001 +0.2847 +0.0004 +0.307 +0.0029 +0 +0 +0.0003 +0.0002 +0.5407 +0.7209 +0.5633 +0.2412 +1.0241 +1.0896 +1.1684 +0.5158 +0.4192 +0.4816 +0.3717 +0.2752 +0.2285 +0.415 +0.1401 +1.281 +0.792 +0.6923 +0.2862 +0.2287 +0.0155 +0.0199 +0.0292 +0.0092 +0.2288 +0.0082 +0.3994 +0.8419 +0.4516 +0.2483 +0.042 +0.046 +0.027 +0.0432 +0.0671 +0.0356 +0.024 +0.036 +0.1495 +0.0203 +0.0329 +0.0333 +0.0017 +0.0002 +0.1161 +0.0013 +0.0116 +0.1165 +0.0096 +0.0064 +0.1182 +0.0243 +0.0164 +0.2744 +0.6677 +0.1901 +0.0073 +0.1478 +0.0378 +0.2164 +0.0522 +0.0004 +0.0502 +0.0005 +0.0559 +0.0367 +0.0128 +0.1765 +0.1085 +0.8614 +1.0286 +1.1856 +0.3952 +0.909 +1.1664 +0.0345 +0.9574 +0.9083 +0.4204 +0.525 +0.7889 +0.112 +0.0591 +1.3121 +0.4922 +0.0377 +0.0346 +0.5026 +0.0361 +0.0286 +0.0066 +0.0161 +0.029 +0.0826 +0.113 +0.0794 +0.0877 +0.079 +0.0871 +0.1718 +0.106 +0 +0.2707 +0.032 +0.8203 +0.0018 +0.0004 +0.0672 +0.0588 +0.0853 +0.0208 +0.0243 +0.0781 +0.0463 +0.0776 +0.0569 +0.0576 +0.1299 +0.0901 +0.1492 +0.1114 +0.082 +0.0007 +0.0364 +0.015 +0.034 +0.0355 +0.0129 +0.0255 +0.0277 +0.0043 +0.0364 +0.0032 +0.0362 +0.0052 +0.0006 +0.0799 +0.007 +0.9222 +0.6419 +0.747 +0.5963 +0.0431 +0.0101 +0.0526 +0.4337 +0.582 +0.1801 +0.5543 +1.5834 +0.9902 +1.0271 +0.2944 +0.0228 +0.0019 +0.0247 +0.0062 +0.0104 +0.012 +0.0349 +0.0605 +0.0473 +0.0014 +0.1037 +0.0364 +0.1059 +0.3117 +0.0628 +0.1863 +0.0823 +0.0263 +0.0028 +0.0025 +0.0394 +0.0004 +0.1221 +0.0473 +0.3666 +0.2158 +0.1839 +0.1636 +0.2814 +0.6179 +0.2643 +0.0941 +0.0702 +0.0083 +0.0139 +0.0652 +0.1763 +0.2559 +0.2501 +0.0054 +0.2246 +0.2249 +0.1703 +0.0283 +0.0237 +0.2398 +0.0127 +0.4064 +0.2011 +0.0508 +0.0139 +0.2378 +0.5523 +0.2381 +0.4346 +0.2298 +0.1689 +0.2523 +0.2128 +0.1032 +0.0052 +0.0004 +0.316 +0.2889 +0.179 +0.152 +0.7989 +0.1681 +0.0467 +0.2342 +0.3767 +0.3379 +0.201 +0.0624 +1.3469 +0.0064 +0.0871 +0.1183 +0.0756 +0.0667 +0.0589 +0.0703 +0.0652 +0.0556 +0.1174 +0.1645 +0.0765 +1.0118 +0.0629 +0.0844 +0.0194 +0.0062 +0.6599 +1.0109 +0.4497 +0.922 +0.5652 +0.5165 +0.4316 +0.5292 +0.4488 +0.5647 +0.5281 +0.209 +0.4305 +0.2273 +0.3527 +0.4538 +0.1271 +0.0204 +1.3302 +0.7475 +0.2617 +0.2358 +0.0318 +0.4353 +0.0455 +0.4293 +0.0441 +0.0129 +0.0123 +0.0247 +0.0025 +0 +0.0166 +0.0107 +0.0479 +0.0265 +0.0131 +0.0108 +0.0064 +0.1545 +0.3182 +0.0006 +0.1344 +0.0031 +0.3208 +0 +0.3388 +0.9895 +0.5872 +0.5186 +0.192 +0.3222 +0.4199 +0.3122 +0.0904 +0.3025 +0.2482 +0.169 +0.2377 +0.4321 +0.2903 +0.2893 +0.1702 +0.1319 +0.0004 +0.9561 +0.3534 +0.6779 +0.0695 +0.1742 +0.25 +0.194 +0.0786 +0.4 +0.0907 +0.0774 +0.1923 +0.1314 +0.1827 +0.2498 +0.7294 +0.5316 +0.0184 +0.0614 +0.0743 +0.0048 +0.011 +0.4405 +0.0134 +1.1834 +0.794 +0.0436 +0.0135 +0.0039 +0.0256 +0.0172 +0.0116 +0.0198 +0.0021 +0.0107 +0.1211 +0.1408 +0.0049 +0.0112 +0.295 +0.3853 +0.1741 +0.6306 +0.656 +0.5824 +0.4786 +0.6335 +0.0181 +0.265 +0.3312 +0.4139 +0.0782 +0.1688 +0.52 +1.0295 +0.3791 +0.2557 +0.6234 +0.0126 +0.4236 +0.4892 +1.2074 +0.0351 +0.1097 +0.3601 +0.1427 +0.3771 +0.1855 +0.1797 +0.0554 +0.2627 +0.1907 +0.409 +0.3734 +0.0701 +0.0302 +0.3341 +0.0068 +0.0244 +0.0511 +0.0755 +0.1473 +0.0885 +0.1503 +0.0756 +0.1261 +0.4349 +0.6868 +0.1958 +0.0007 +0.0745 +0.0002 +0.0009 +0.0497 +0.0001 +0.0052 +0.8779 +0.3778 +0.2833 +0.166 +0.0531 +0.0759 +1.164 +1.271 +0.1465 +0.0249 +0.1444 +0.1822 +0.1839 +0.1838 +0.0218 +0.1685 +0.1803 +0.1191 +0.4805 +0.1721 +0.1804 +1.0611 +0.1812 +0.1821 +0.1013 +1.4627 +0.3128 +0.0265 +0.1536 +0.3186 +0.3864 +0.2435 +0.3055 +0.0618 +1.3585 +0.1355 +1.0074 +0.2108 +0.1264 +0.161 +0.2218 +0.2246 +0.108 +0.0214 +0.2408 +0.2691 +0.0203 +0.146 +0.1532 +0.1295 +0.1672 +0.195 +0.1319 +0.1272 +0.1847 +0.1674 +0.2445 +0.155 +0.1126 +0.1282 +0.0533 +0.1749 +0.1147 +0.3324 +0.0219 +0.0309 +0.2728 +0.2227 +0.6678 +0.5551 +0.1524 +0.0768 +0.0655 +0.4544 +0.0325 +0.0654 +0.06 +0.0059 +0.0792 +0.12 +0.0515 +0.0974 +0.2284 +0.0785 +0.1692 +0.04 +0.0018 +0.1763 +0.2141 +0.239 +0.1556 +0.1584 +0.0856 +0.1591 +0.1593 +0.0593 +0.1417 +0.132 +0.0135 +0.0015 +0.1286 +0.1505 +0.0321 +0.046 +0.2306 +0.3994 +0.5334 +0.2267 +0.028 +0.1781 +0.2084 +0.0488 +0.13 +0.5569 +1.0996 +0.4802 +0.0957 +0.6279 +0.2675 +0.2977 +0.1525 +0.3683 +0.047 +0.2756 +0.3223 +0.4114 +0.2999 +0.2807 +0.1141 +0.2567 +0.3409 +0.1686 +0.0756 +0.2439 +0.2638 +0.2181 +0.1101 +0.2129 +0.2324 +0.2389 +0.2107 +0.0021 +1.1823 +1.6128 +1.3251 +1.2078 +1.0795 +1.141 +0.5826 +1.0114 +0.4818 +0.0421 +0.9495 +0.0095 +0.0697 +0.2343 +0 +1.0325 +1.215 +0.0021 +0.0002 +0.0372 +0.1606 +0.3756 +0.3317 +0.0554 +0.0354 +0.0909 +0.0767 +0.1626 +0.2094 +0.1602 +0.1951 +0.1044 +0.1086 +0.1789 +0.0986 +0.4102 +0.7747 +0.7219 +0.1831 +0.0053 +1.0798 +0.1639 +0.0692 +0.0552 +0.0768 +0.8023 +0.1887 +0.1475 +0.146 +0.0819 +1.3597 +1.1716 +1.0578 +0.0278 +0.0105 +0.1071 +0.0382 +0.0424 +0.1012 +0.0505 +0.0288 +0.3902 +0.0712 +0.8312 +0.7744 +0.82 +0.0816 +0 +0.1212 +1.5374 +0.7836 +0.7623 +0.6269 +0.0358 +0.7722 +0.2306 +0.0872 +1.2303 +0.2093 +0.0168 +0.0102 +0 +0.0962 +0.0376 +0.0565 +0.0568 +0.1194 +0.0353 +0.0026 +0.0699 +0.0024 +0.016 +0.0015 +0.3304 +0.8583 +0.392 +0.6435 +0.6287 +0.3957 +0.4209 +0.0994 +0.2989 +0.1266 +0.2838 +0.2612 +0.1599 +0.1264 +0.3337 +0.2076 +0.0385 +0.2035 +0.1743 +0.0553 +0.6883 +0.5941 +0.7062 +0.3209 +0.3183 +0.1004 +0.233 +0.2356 +0.252 +0.1901 +0.1137 +0.2235 +0.2619 +0.0005 +0 +0.1217 +0.0539 +0.0478 +0.0271 +0.0142 +0.2308 +0.5016 +0.5566 +0.3922 +0.1609 +0.2614 +0.2387 +0.28 +0.0116 +0.4108 +0.0592 +0.0019 +0.0423 +0.3541 +0.3212 +0 +0.9629 +0.0984 +0.2626 +0.2815 +0.0011 +0.2499 +0.451 +0.4095 +0.245 +0.2115 +0.2709 +0.3734 +0.2855 +0.0094 +1.7022 +0.1219 +0.2465 +0.0529 +0.1562 +0.2729 +0.0891 +0.2418 +0.3496 +0.4988 +0.7376 +0.0302 +0.2592 +0.1888 +0.1916 +0.3175 +0.455 +0.2396 +0.2999 +0.9686 +0.2865 +0.2296 +0.0078 +0.0499 +0.1133 +0.0952 +0.0384 +0.0536 +0.142 +0.0058 +1.4224 +0.8304 +0.6918 +0.6009 +0.5095 +0.4329 +0.3536 +0.3269 +0.3087 +0.247 +0.3091 +1.0684 +0.3122 +0.2253 +0.4067 +0.2725 +0.1566 +0.779 +0.07 +0.0165 +0.2316 +0.7223 +0.6121 +0.5082 +0.3503 +0.4154 +0.2001 +0.0679 +0.2206 +0.071 +0.03 +0.0887 +0.0146 +0.0661 +0.18 +0.0054 +0.0192 +0.1307 +0.049 +0.0112 +0.0134 +0.016 +0.1539 +0.2708 +0.0497 +0.2326 +0.181 +0.0757 +0.144 +0.1489 +0.1726 +0.0865 +0.0264 +0.226 +0.566 +1.1295 +1.0403 +0.2024 +0.1325 +0.047 +0.0598 +0.0488 +0.0218 +0.1849 +0.0176 +0.3404 +0 +0.0762 +0.1441 +0.0595 +0.0141 +0.1048 +0.6498 +0.308 +0.248 +0.3627 +0.2892 +0.2473 +0.2547 +0.3223 +0.205 +0.2204 +0.1952 +0.1269 +0.1741 +0.1445 +0.5406 +0.6092 +0.1081 +0.1379 +1.0776 +0.0277 +0.8059 +0.7833 +0.0972 +0.8423 +0.4735 +0.2642 +0.1051 +1.0904 +0.6942 +0.1331 +0.7239 +0.6764 +0.0991 +0.5322 +0.0679 +0.1206 +0.2041 +0.3844 +0.1173 +0.2604 +0.0359 +0.1257 +0.1274 +0.247 +0.0819 +0.0459 +0.0143 +0.0669 +0.7104 +0.1402 +0.4941 +0.0282 +0.267 +0.2141 +0.0893 +0.0739 +0.0801 +0.1113 +0.1954 +0.1442 +0.0861 +0.0841 +0.0614 +0.0007 +0.0954 +0.0677 +0.0794 +0.0465 +0.0092 +0.0202 +0.0921 +1.1713 +0.9894 +0.5019 +0.0102 +0.146 +1.065 +1.4885 +1.3624 +0.1698 +0.0141 +0.028 +0.07 +0.0005 +0.0465 +0.0583 +0.0249 +0.1103 +0.0115 +0 +0.0012 +0.7441 +0.7023 +0.0038 +0.4113 +0.5805 +0.1001 +0.1741 +0.2424 +0.0024 +0.002 +0.1355 +0.1201 +0.2795 +0.1979 +0.183 +0.0029 +0.8697 +0.1024 +0.5073 +1.4577 +1.182 +1.2971 +0.9138 +1.0686 +0.06 +1.398 +1.2628 +0.991 +0.9119 +0.916 +0.7941 +0.0794 +0.0204 +0.0656 +0.1529 +0.6835 +0.8853 +0.7196 +0.4746 +0.4803 +0.4339 +0.8934 +0.778 +0.7337 +0.5661 +0.8164 +1.1243 +0.6308 +0.0741 +0.5499 +0.6253 +1.2658 +1.2307 +1.2811 +0.7278 +0.5012 +0.717 +0.2928 +0.2545 +0.1966 +1.0109 +0.4586 +0.708 +0.7095 +1.1758 +1.1833 +1.342 +0.7601 +0.3807 +0.413 +0.3034 +1.0881 +0.8993 +0.8496 +0.0154 +0.5279 +0.3857 +0.3247 +0.3584 +0.5384 +0.0168 +1.2625 +0.8625 +0.0066 +0.1639 +0.1689 +0.0228 +0.3776 +0.0425 +0.268 +0.2233 +0.1038 +0.2244 +0.0411 +0.1202 +0.1204 +0.0047 +0.0278 +0.0388 +0.1393 +0 +0.388 +0.0824 +0.7966 +0.0221 +0.02 +0.0086 +0.0122 +0.0043 +0.2263 +0.079 +0.0179 +0.0422 +0.1551 +0.3623 +0.7399 +0.0062 +0.0958 +0.8107 +0.4066 +0.388 +0.4066 +0.0146 +0.1082 +0.2018 +0.0488 +0.0107 +0.1543 +0.0944 +0.0169 +0.17 +0.8317 +0.0253 +0.4702 +0.2564 +0.2851 +0.6193 +0.0178 +0.3414 +0.019 +0.1457 +0.4569 +0.2655 +0.2398 +0.079 +0.0105 +0.1497 +0.128 +0.6562 +0.6462 +0.491 +0.6737 +0.8722 +0.411 +0.6295 +0.2519 +0.2023 +0.4683 +0.9588 +0.9813 +0.0079 +0.041 +0.2864 +0.0032 +0.088 +0.1334 +0.1479 +1.063 +0.3662 +0.0153 +0.0515 +0.004 +0.0567 +0.0268 +0.1133 +0.1975 +0.1201 +0.7673 +0.1611 +0.2365 +0.249 +0.2645 +0.0539 +0 +0 +0 +0.3625 +0.117 +0.1809 +0.0001 +0.0293 +0.0019 +0.1682 +0.2909 +0.2851 +0.6536 +0.2154 +0.2442 +0.0785 +0 +0 +0.6887 +0 +0.5281 +0.5921 +0.1374 +0.4644 +0.3296 +0.2482 +0.2843 +0.3935 +0.0001 +0 +0.1584 +0 +0.0667 +0.3035 +0.1812 +1.004 +0.704 +0.0169 +0.742 +0.3094 +0.2778 +0.3128 +0.1381 +0.0209 +0.0568 +0.1429 +0 +0.1415 +0.216 +0.8025 +0.1608 +0.0131 +0.1395 +0.2676 +0.1959 +0.2163 +0.0098 +0.2181 +0.0145 +0.9417 +0.0444 +0.0949 +0.0041 +0.0001 +0.2365 +0 +0.1871 +0.1274 +0.5115 +1.5567 +1.1931 +0.5066 +0.7553 +0.3258 +0.0378 +0.0217 +1.1501 +0.7313 +0.0613 +0.0436 +0.0369 +0.0187 +0.0056 +0.2064 +0.6627 +0.5664 +0.2415 +0.069 +0.022 +0.9074 +1.1465 +0.3695 +0.1252 +0.1026 +0.3631 +0.1471 +0.7724 +0.9496 +1.0816 +0.2809 +0.023 +0.3982 +1.1291 +1.0098 +1.0703 +0.3743 +1.5425 +0.6847 +1.0085 +0.021 +0.0687 +0.0164 +0.0233 +0.0024 +0.2962 +0.0954 +0.0736 +0.0392 +0.0001 +0.6641 +0.0716 +0.1721 +0.3286 +0.3171 +0.0985 +0.0313 +0.1815 +0.043 +0.7311 +0.7895 +0.315 +0.3519 +1.3985 +0.0251 +0.0878 +0.9918 +1.2437 +0.9538 +0.1242 +0.022 +0.0297 +0.0448 +0.1678 +0.0311 +0.0145 +0.02 +0.7033 +0.1484 +0.1192 +0.0404 +0.0008 +0.016 +0.0011 +0.0029 +0.0027 +0.0038 +0.004 +0.0065 +0.0152 +0.0001 +0.004 +0.1877 +0.0045 +0.0044 +0.0013 +0.0051 +0.4168 +0.9097 +0.6087 +0.4493 +0.218 +0.0625 +0.1401 +0.0573 +0 +0.0391 +0.6023 +0.2378 +0.5939 +0.2842 +1.0667 +0.0131 +0.6194 +0.462 +0.2444 +0.0206 +0.2021 +1.278 +1.2098 +1.1843 +0.9891 +0.0545 +0.1777 +0.0361 +0.2475 +0.0072 +1.0226 +0.8708 +0.7069 +0.317 +0.4305 +0.0606 +1.2344 +0.9392 +0.6697 +1.4529 +1.2431 +0.3731 +1.5269 +1.5519 +1.6152 +1.4955 +0.0004 +0.0006 +0.0198 +0.6009 +0.002 +0.0038 +0.0007 +0.0004 +0.2765 +0.3245 +0.8685 +0.7911 +1.2058 +0.294 +0.2796 +0.7987 +0.0838 +0.0994 +0.7336 +0.0003 +0.0488 +0.0001 +0.5383 +0.165 +0.671 +0.381 +0.3993 +0.6781 +0.0816 +0.1468 +0.6156 +0.1933 +0.3881 +0.0931 +0.2461 +0.0003 +0.0306 +0.001 +0.3887 +0.0928 +0.1882 +0.1008 +0.002 +0.0321 +0.0156 +0.0481 +0.0965 +0.0032 +0.001 +0.0049 +0.0027 +0.1943 +0.0004 +0 +0.0048 +0.4727 +0 +0.3504 +0 +0.037 +0.2856 +0 +0.0028 +0.0032 +0.0027 +0.0024 +0.0084 +0.0013 +0.154 +0.0017 +0.0126 +0.0622 +0.0175 +0.4152 +0.0289 +0.016 +0.0803 +0.0006 +0.0441 +0.0007 +0.0006 +0.0124 +0.0185 +0.0065 +0.0007 +0.0273 +0.0058 +0.0157 +0.0006 +0.0006 +0.0066 +0.0001 +0.5068 +0.0205 +0.0315 +0.0015 +0.0033 +0.1659 +0.1685 +0.1087 +0.0148 +0.0057 +0.1097 +0.2979 +0.1486 +0.0344 +0.0249 +0.1281 +0.1406 +0.0102 +0.0161 +0.0061 +0.0078 +0.088 +0.013 +0.0066 +0.0046 +0.1171 +0.0187 +0.0054 +0.031 +0.0151 +0.0084 +0.0021 +0.006 +0.0104 +0.0003 +0.0138 +0.0471 +0.011 +0.0001 +0.0004 +0.0128 +0.0019 +0.0087 +0.0103 +0 +0.0009 +0.0364 +0.0165 +0 +0.0155 +0.0015 +0.1356 +0.0017 +0.0612 +0.2504 +0.0809 +0.003 +0.0182 +0.0148 +0.003 +0.0308 +0.0482 +0.1672 +0.0035 +0 +0.0019 +0.0244 +0.0022 +0.0127 +0.0049 +0.0016 +0.0823 +0.0295 +0.0067 +0.0043 +0.2266 +0.7548 +0.1318 +0.2404 +0.6864 +0.7357 +0.0054 +0.2819 +0.0675 +0.0425 +0.5904 +0.791 +0.408 +0.5909 +0.0094 +0.0988 +0.3624 +0.2944 +0.7595 +0.0434 +0.4396 +0.6039 +0.19 +0.0307 +0.6636 +0.395 +0.5219 +0.0015 +0.1066 +0.109 +0.0724 +0.0263 +0.0482 +0.0017 +0.1559 +0.0255 +0.0044 +0.0052 +0.0186 +0.0353 +0.0012 +0.0515 +0.0517 +0.0129 +0.091 +0.1835 +0.0001 +0.0695 +0.0008 +0.0074 +0.0082 +0.0087 +0.0006 +0.0173 +0.004 +0.0067 +0.0029 +0.0225 +0.0272 +0.0031 +0.0005 +0.0221 +0.0038 +0.0861 +0.0155 +0.0163 +0.0045 +0.0745 +0.0339 +0.0013 +0.0073 +0.0048 +0.0107 +0.0032 +0.0326 +0.0065 +0.0255 +0.02 +0.0125 +0.0052 +0.0033 +0.009 +0.0008 +0.001 +0.0013 +0.0166 +0.0155 +0.0745 +0.0244 +0.0155 +0.0103 +0.0227 +0.1997 +0.0401 +0.0297 +0.0091 +0.0337 +0.0129 +0.0726 +0.0266 +0.0464 +0.0055 +0.0005 +0.0027 +0.0001 +0.0091 +0.0003 +0.005 +0.0015 +0.3992 +0.0034 +0.0113 +0.0068 +0.0116 +0.0078 +0.0181 +0.0087 +0.0603 +0.4355 +0.0122 +0.0003 +0.0297 +0.0047 +0.4182 +0.0054 +0.374 +0.1218 +0.0033 +0.018 +0.0616 +0.0165 +0.0204 +0.0041 +0.0934 +0.0019 +0.0011 +0.054 +0.0021 +0.0612 +0.0455 +0.1277 +0.0699 +0.0154 +0.0609 +0.0023 +0.0395 +0.017 +0.0089 +0.0302 +0.0563 +0.0228 +0.001 +0.1875 +0.365 +0.0038 +0.0988 +0.067 +0.0005 +0.0001 +0 +0.0703 +0.0007 +0.0029 +0.0008 +0.4836 +0.0019 +0.0016 +0.0115 +0.0005 +0.0003 +0.0005 +0.2245 +0.0018 +0.0003 +0.0006 +0.0029 +0.0001 +0.0003 +0.4657 +0.0001 +0.0555 +0.0313 +0.2205 +0.4972 +0.1051 +0.0001 +0.0398 +0.0036 +0.011 +0.0028 +0.0009 +0.0041 +0.2182 +0.0004 +0.0098 +0.1095 +0.001 +0.0013 +0 +0.0006 +0 +0.2398 +0.002 +0.0033 +0.0002 +0.005 +0.0002 +0.0006 +0.1755 +0.0094 +0.0005 +0.0003 +0.0502 +0.0533 +0.1777 +0.0016 +0.0912 +0.0147 +0.0056 +0 +0.1127 +0.1197 +0.1047 +0.0048 +0.0149 +0.4621 +0.3174 +0.2705 +0.0923 +0.0426 +0.1859 +0.0024 +0.0165 +0.0123 +0.0032 +0.0242 +0.2032 +0.2871 +0.0015 +0.0043 +0.0086 +0.2845 +0.0068 +0.003 +0.0115 +0.0367 +0.0104 +0.315 +0.0388 +0.0065 +0.0022 +0.0303 +0.0002 +0.3533 +0.0095 +0.0337 +0.0281 +0.2655 +0.0716 +0.0139 +0.2277 +0.3319 +0.0064 +0.2383 +0.4414 +0.016 +0.4123 +0.2714 +0.0103 +0.01 +0.0996 +0.0182 +0.0049 +0.2174 +0.0383 +0.116 +0.3546 +0.5057 +0.0729 +0.0007 +0.0405 +0.001 +0.0012 +0.0009 +0.0015 +0.0194 +0.0009 +0.0458 +0.0001 +0.0014 +0.0166 +0.1162 +0.0369 +0.1234 +0.2603 +0.0068 +0.0758 +0.0185 +0.0126 +0.0044 +0.0214 +0.0239 +0.1209 +0.1288 +0.0317 +0.1882 +0.0442 +0.0302 +0.014 +0.1194 +0.1062 +0.0599 +0.0008 +0.2672 +0.0046 +0.027 +0.2058 +0.0477 +0.7413 +0.3959 +0.3698 +0.1776 +0.1233 +0.0684 +0.1809 +0.0463 +0.0097 +0.1455 +0.0053 +0.2283 +0.0908 +0.0324 +0.4633 +0.1766 +0.1408 +0.3118 +0.0011 +0.3301 +0.1476 +0.0533 +0.0107 +0.0287 +0.2226 +0.199 +0.0231 +0.3886 +0.2349 +0.1988 +0.3008 +0.0033 +0.0001 +0.0165 +0.289 +0.0019 +0.212 +0.0239 +0.1133 +0.267 +0.3936 +0.4119 +0.0907 +0.0071 +0.0026 +0.0134 +0.0034 +0.078 +0.1613 +0.2664 +0.2243 +0.3858 +0.0804 +0.0602 +0.043 +0.1174 +0.0055 +0.0807 +0.0028 +0.0049 +0.1095 +0.0451 +0.0786 +0.0831 +0.0133 +0.3438 +0.002 +0 +0.0004 +0.0006 +0.0008 +0.003 +0.0063 +0.0004 +0.0027 +0.0033 +0.0024 +0.0017 +0.0024 +0.0033 +0.3333 +0.0042 +0.0135 +0.0003 +0.0001 +0.0011 +0.001 +0 +0.0036 +0.0044 +0.001 +0.0004 +0.0046 +0.0125 +0.0001 +0.0033 +0.0026 +0.0004 +0.0135 +0.0674 +0.0176 +0.0282 +0.0069 +0.043 +0.0092 +0.0025 +0.0214 +0.0213 +0.0001 +0.0144 +0.0065 +0.0371 +0.023 +0.0381 +0.06 +0.0085 +0.0621 +0.0318 +0.1388 +0.1025 +0.0383 +0.001 +0.0015 +0.0301 +0.0802 +0.0222 +0.0003 +0.0584 +0.0782 +0.011 +0.0403 +0.0704 +0.0777 +0.0114 +0.146 +0.0085 +0.0714 +0.0847 +0.0003 +0.0003 +0.0032 +0.0653 +0.0004 +0.3632 +0.1129 +0.1983 +0.3406 +0.1167 +0.1612 +0.0081 +0.0868 +0.1093 +0.0239 +0.0351 +0.1112 +0.0525 +0.017 +0.0033 +0.0529 +0.209 +0.1797 +0.0629 +0.1059 +0.1006 +0.0016 +0.0117 +0.3033 +0.0635 +0.014 +0.0057 +0.1127 +0.0975 +0.0767 +0.0758 +0.0161 +0.1249 +0.1407 +0.1328 +0.0787 +0.0839 +0.045 +0.0532 +0.0674 +0.0969 +0.0969 +0.0704 +0.0477 +0.0541 +0.0017 +0.0457 +0.0232 +0.0671 +0.1041 +0.0015 +0.0911 +0.1748 +0.1637 +0.217 +0.389 +0.2725 +0.1757 +0.2086 +0.1756 +0.1679 +0.1379 +0.1065 +0.0736 +0.1638 +0.1102 +0.0717 +0.1223 +0.0928 +0.139 +0.0027 +0.0059 +0.0019 +0.0015 +0.0014 +0.0017 +0.0022 +0.0068 +0.0001 +0 +0.0004 +0.0032 +0.0028 +0.0031 +0.0109 +0.0004 +0.0039 +0.0035 +0.0115 +0.0077 +0.0517 +0.0002 +0.0084 +0.0133 +0.0004 +0.0031 +0.0894 +0.0032 +0.002 +0.001 +0.0028 +0.0014 +0.0015 +0.0503 +0.0122 +0.0018 +0.0085 +0.0008 +0.0069 +0.0053 +0.006 +0.0038 +0.0734 +0.0757 +0.0857 +0.0009 +0.0013 +0.0009 +0.0105 +0.0047 +0.0009 +0.0187 +0.0001 +0.0034 +0.0014 +0.009 +0.0003 +0.0292 +0.0058 +0.0332 +0.0039 +0.7114 +0.7166 +0.0104 +1.0225 +1.0836 +0.4115 +0.0246 +0.2584 +0.5622 +0.2692 +0.0306 +0.1978 +0.2329 +0.5353 +0.4572 +0.2332 +0.2252 +0.0406 +0.013 +0.0091 +0.0029 +0.0582 +0.001 +0.0026 +0.0157 +0.0105 +0.0235 +0.0054 +0.0537 +0.0369 +0.0174 +0.0145 +0.016 +0.0012 +0.0204 +0.003 +0.0058 +0.0096 +0.0418 +0.0045 +0.0005 +0.0064 +0.0467 +0.0246 +0.0583 +0.0044 +0.0487 +0.0288 +0.0001 +0.0568 +0.0024 +0.009 +0.0002 +0.261 +0.162 +0.0876 +0.216 +0.022 +0.0009 +0.0046 +0.024 +0.0031 +0.1006 +0.0002 +0.1603 +0.7859 +0.6994 +0.0226 +0.0032 +0.0024 +0.0109 +0.0117 +0.0033 +0.0964 +1.2722 +1.0146 +0.5036 +0.0144 +0.0694 +0.0101 +0.3064 +0.1764 +0.1415 +0.1202 +0.0975 +0.0362 +0.0543 +0.0926 +0.0686 +0.0473 +0.3661 +1.6101 +0.0453 +0.3124 +0.6076 +0.0192 +0.0915 +0.3377 +0.5223 +1.0639 +1.4152 +1.0777 +0.8797 +1.4791 +0.6893 +0.6885 +0.7954 +0.7037 +0.6496 +0.002 +0.0047 +0.0862 +0.0084 +0.0347 +0.0322 +0.0091 +0.0048 +0.1001 +0.0223 +0.0589 +0.0596 +0.8839 +0.8607 +0 +0.0009 +0.0004 +0.0001 +0.0008 +0.0002 +0.0019 +0.0007 +0.001 +0.0004 +0.0001 +0.007 +0.0065 +0.0061 +0.0003 +0.0003 +0.0001 +0.0007 +0.0001 +0.0478 +0.0013 +0.0023 +0.0667 +0.1099 +0.0105 +0.0208 +0.0262 +0.1011 +0.0551 +0.0062 +0.0244 +0.0299 +0.0039 +0.029 +0.1012 +0.0158 +0.0122 +0.0267 +0.0857 +0.0212 +0.0259 +0.0104 +0.0182 +0.0023 +0.0022 +0.0403 +0.0165 +0.0163 +0.0109 +0.0072 +0.1489 +0.0173 +0.0017 +0.4653 +0.4994 +0.0424 +0.9027 +0.0228 +0.676 +0.5384 +0.6438 +0.4359 +0.1581 +0.5996 +0.648 +0.2733 +0.088 +0.1926 +0.3133 +0.0269 +0.5106 +0 +0.0104 +0.0036 +0.0383 +0.0107 +0.0038 +0.0034 +0.0645 +0.0327 +0.0428 +0.1308 +0.092 +0.3843 +0.072 +0.0144 +0.401 +0.2499 +0.0281 +0.0025 +0.0189 +0.0307 +0.0003 +0.1192 +0.0049 +0.0548 +0.2461 +0.0628 +0.2676 +0.1567 +0.0874 +0.008 +0.0194 +0.1361 +0.0005 +0.0866 +0.0011 +0.0865 +0.0045 +0.5187 +0.2056 +1.3213 +0.1543 +0.0007 +0.3006 +0.1674 +0.3893 +0.6965 +0.0678 +0.1523 +0.4255 +0.0384 +0.0075 +0.0034 +0.2882 +0.3978 +0.3047 +0.006 +0.0532 +0.2594 +0.102 +0.1016 +0.2197 +0.2516 +0.3315 +0.1756 +0.0296 +0.6982 +0.5161 +0.2868 +0.0286 +0.112 +0.0651 +0.018 +0.3253 +1.6264 +0.1665 +1.2202 +0.2333 +1.3357 +1.3151 +0.094 +0.0289 +0.4492 +1.1314 +0.0939 +0.5195 +0.9306 +0.2744 +0.0997 +0.1782 +0.4479 +0.1475 +1.1088 +0.9998 +0.6489 +0.4642 +0.1807 +1.3824 +0.7576 +0.1855 +0.4775 +0.0025 +0.1277 +0.0668 +0.1125 +0.0749 +0.2902 +0.2815 +0.6896 +0.0659 +0.0321 +0.2963 +0.2334 +0.3996 +0.0572 +0.2602 +0.067 +0.0406 +0.1348 +0.0883 +0.0504 +0.0475 +0.017 +0.2524 +0.0783 +0.0177 +0.1062 +0.3064 +0.106 +0.0925 +0.0574 +0.0147 +0.0907 +0.2559 +0.0246 +0.0413 +0.0259 +0.0408 +0.1022 +0.0482 +0.0626 +0.0453 +0 +0.1958 +0.1344 +0.0384 +0.1388 +0.0028 +0.1289 +0.0509 +0.0636 +0.0232 +0.0697 +0.0937 +0.0381 +0.0721 +0.003 +0.0033 +0.0015 +0.0179 +0.0564 +0.0038 +0.0002 +0.062 +0.0232 +0.0014 +0.0009 +0.0009 +0.1375 +0.0489 +0.0077 +0.0481 +0.2476 +0.2914 +0.1667 +0.0147 +0.0181 +0.2047 +0.1514 +0.0175 +0.0417 +0.0028 +0.1253 +0.1459 +0.0997 +0.0783 +0.0598 +0.1038 +0.0669 +0.1108 +0.0351 +0.0012 +0.0084 +0.0447 +0.8784 +0.8175 +0.2444 +0.979 +0.0921 +0.5894 +0.8229 +0.2279 +0.0354 +0.1058 +0.0176 +0.0276 +0.0503 +0.192 +0.1954 +0.0708 +0.2926 +0.0376 +0.0229 +0.1852 +0.0186 +0.0002 +0.0002 +0.012 +0.0848 +0.0206 +0.0373 +0.0651 +0.037 +0.053 +0.0621 +0.0232 +0.0003 +0.0253 +0.0605 +0.0135 +0.033 +0.0664 +0.1903 +0.1075 +0.022 +0.0051 +0.3337 +0.2433 +0.0136 +0.1591 +0.1879 +0.0213 +0.0794 +0.026 +0.0301 +0.0419 +0.0019 +0.0135 +0.1099 +0.118 +0.1198 +0.3294 +0.2569 +0.0089 +0.0199 +0.0018 +0.0081 +0.0072 +0.0956 +0.0114 +0.0098 +0.0408 +0.0162 +0.0027 +0.0233 +0.0091 +0.0346 +0.0473 +0.0323 +0.0369 +0.0687 +0.0206 +0.0028 +0.0586 +0.0498 +0 +0.0265 +0.2895 +0.3942 +0.0043 +0.9259 +0.0236 +0.5678 +0.1945 +0.227 +0.6681 +0.8701 +0.1945 +0.0422 +0.0203 +0.0129 +0.0039 +0.0495 +0.2105 +0.2059 +0.0797 +1.0396 +0.4527 +0.0456 +0 +0.2214 +0.0897 +0.0049 +0.285 +0.215 +0.0075 +0.1132 +0.0529 +0.1819 +0.1877 +0.0758 +0.1368 +0.0985 +0.0769 +0.1676 +0.0875 +0.1114 +0.1258 +0.5408 +0.1211 +0.1245 +0.0792 +0.0414 +0 +0.0007 +0.0003 +0 +0.0013 +0.0001 +0.0033 +0.0011 +0.0003 +0.0024 +0.001 +0.0012 +0.0003 +0.0132 +0.0011 +0.0033 +0.0006 +0.0015 +0.0322 +0 +0.0001 +0 +0.0024 +0.0627 +0.041 +0.0114 +0.0029 +0.0578 +0.0034 +0.0666 +0.023 +0.003 +0.0918 +0.8079 +0.1115 +0.1074 +0.1215 +0.138 +0.0073 +0.009 +0.1461 +0.0112 +0.0982 +0.0322 +0.3364 +0.009 +0.0082 +0.3042 +0.1503 +0.0764 +0.0436 +0.0059 +0.001 +0.1246 +0.0201 +0.1031 +0.0962 +0.1832 +0.0058 +0.0914 +0.0077 +0.0337 +0.0928 +0.0869 +0.0181 +0.029 +0.0321 +0.1168 +0.2378 +0.1905 +0.1404 +0.0271 +0.0214 +0.001 +0.0008 +0.0066 +0.0471 +0.009 +0.0385 +0.069 +0.4654 +0.2071 +0.0036 +0.0546 +0.098 +0.0185 +0.0382 +0.0469 +0.0036 +0.0018 +0.0325 +0.0003 +0.0289 +0.0713 +0.082 +0.3216 +0.0057 +0.5661 +0.6623 +0.4397 +0.1188 +0.6307 +0.4667 +0.2129 +0.1067 +0.3079 +0.3285 +0.0234 +0.3697 +0.1806 +0.4227 +0.0505 +0.4026 +0.2468 +0.2157 +0.0942 +0.0007 +0.087 +0.0794 +0.1263 +0.0761 +0.0354 +0.0687 +0.0713 +0.0662 +0.0079 +0.0902 +0.0709 +0.1009 +0.7327 +0.0067 +0.9791 +1.0834 +0.6281 +0.1876 +0.5563 +0.3453 +0.3544 +0.5964 +0.0227 +0.327 +0.4936 +0.2635 +0.4089 +1.0628 +0.6804 +0.179 +0.0046 +0.0411 +0.0007 +0.0025 +0.0001 +0.0127 +0.0773 +0.0003 +0.0036 +0.0011 +0.0482 +0.0183 +0.0043 +0.005 +0.0587 +0.1184 +0.0003 +0.2097 +0.0027 +0.0247 +0.0336 +0.0379 +0.2458 +0.362 +0.2085 +0.0025 +0.1118 +0.0434 +0.0307 +0.1594 +0.1446 +0.0303 +0.0547 +0.1742 +0.0947 +0.1695 +0.2022 +0.1582 +0.0131 +0.0049 +0.2341 +0.259 +0.0056 +0.0043 +0.149 +0.0243 +0.0006 +0.0145 +0.0024 +0.0214 +0.1103 +0.1495 +0.0367 +0.0224 +0.0141 +0.2288 +0.047 +0.2656 +0.1666 +0.0558 +0.0465 +0.2656 +0.2466 +0.2137 +0.0023 +0.2044 +0.0084 +0.0076 +0.0556 +0.1511 +0.2697 +0.1758 +0.0044 +0.1024 +0.0659 +0.0356 +0.0386 +0.1597 +0.0694 +0.0346 +0.0491 +0.0648 +0.0215 +0.0262 +0.0053 +0.0484 +0.0227 +0.0772 +0.1457 +0.0915 +0.0349 +0.1713 +0.2431 +0.0112 +0.2009 +0.2099 +0.2105 +0.1202 +0.1988 +0.1148 +0.1819 +0.1544 +0.1211 +0.0161 +0.0025 +0.0531 +0.0194 +0.0109 +0.0111 +0.1043 +0.0684 +0.0261 +0.0385 +0.0765 +0.0195 +0.0707 +0.0513 +0.0276 +0.0434 +0.0331 +0.0488 +0.0484 +0.0173 +0.0735 +0.0001 +0.0765 +0.1025 +0.0258 +0.0708 +0.0426 +0.0534 +0.0115 +0.0778 +0.0383 +0.002 +0.1123 +0.0017 +0.0093 +0.1777 +0.3525 +0.0189 +0.22 +0.1998 +0.0013 +0.0063 +0.1334 +0.0363 +0.1775 +0.2043 +0.0845 +0.1296 +0.0882 +0.0244 +0.1075 +0.003 +0.0314 +0.0162 +0.0116 +0.0005 +0.1339 +0.0287 +0.0067 +0.0539 +0.0256 +0.0004 +0.0006 +0.0025 +0.0033 +0.0006 +0.1059 +0.0806 +0.0475 +0.1052 +0.0085 +0.0035 +0.6503 +0.4642 +0.0226 +0.3798 +0.2305 +0.4885 +0.3508 +0.3309 +0.3028 +0.1911 +0.3229 +0.2683 +0.2902 +0.2843 +0.2673 +0.5714 +0.767 +0.3785 +0.0186 +0.0033 +0.0889 +0.0698 +0.0032 +0.2793 +0.1175 +0.1753 +0.0839 +0.1343 +0.0956 +0.004 +0.0184 +0.0018 +0.0949 +0.071 +0.1772 +0.0303 +0.0869 +0.0023 +0.0068 +0.0058 +0.0797 +0.2629 +0.0993 +0.0953 +0.0145 +0.0214 +0.0058 +0.1292 +0.0818 +0.0061 +0.0039 +0.0028 +0.0554 +0.0564 +0.1778 +0.1621 +0.1432 +0.0931 +0.0724 +0.0053 +0.0289 +0.2274 +0.1251 +0.0448 +0.0429 +0.6271 +0.3315 +0.0806 +0.136 +0.0532 +0.0489 +0.0561 +0.0116 +0.0853 +0.0626 +0.185 +0.0395 +0.6566 +0.0672 +0.1456 +0.0001 +0.3889 +0.0678 +0.1664 +0.146 +0.1416 +0.0025 +0.0064 +0.27 +1.0846 +0.0015 +0.2912 +0.204 +1.0053 +0.2407 +0.5026 +0.0646 +0.2302 +0.2377 +0.7002 +1.5298 +0.1665 +1.0826 +1.637 +0.0663 +1.1943 +0.9741 +1.1438 +0.9319 +0.0075 +0.049 +1.0242 +0.0873 +0.5033 +0.2499 +0.5336 +0.5891 +0.6856 +0.2926 +0.0071 +0.0177 +0.0253 +0.0287 +0.0303 +0.0912 +0.0268 +0.0137 +0.0013 +0.0263 +0.0133 +0.0069 +0.0131 +0.0278 +0.0212 +0.3235 +0.0086 +0.0022 +0.0078 +0.032 +0.085 +0.0175 +0.18 +0.2888 +0.0211 +0.0523 +0.186 +0.3113 +0.0263 +0.0703 +0.0909 +0.0104 +0.0042 +0.0153 +0.0926 +0.0073 +0.0001 +0.0135 +0.0649 +0.064 +0.0258 +0.0145 +0.0335 +0.0076 +0.0073 +0.0909 +0.0058 +0.0089 +0.0145 +0.0157 +0.0076 +0.0078 +0.0071 +0.0081 +0.0093 +0.0319 +0.0338 +0.0273 +0.1153 +0.0414 +0.0644 +0.0362 +0.0168 +0.0341 +0.0241 +0.0833 +0.0162 +0.0308 +0.0414 +0.0072 +0.0306 +0.0259 +0.0527 +0.0426 +0.0449 +0.03 +0.2644 +0.0036 +0.1793 +0.1621 +0.2499 +0.0219 +0.7925 +0.5145 +0.0164 +0.6871 +0.3448 +0.058 +0.0354 +0.4897 +0.2186 +0.0805 +0.0395 +0.081 +0.1407 +0.2391 +0.593 +0.9805 +0.1779 +0.1217 +0.6345 +0.0368 +0.3638 +0.0504 +0.0548 +0.1748 +0.007 +0.008 +0.0423 +0.0014 +0.0765 +0.0257 +0.0011 +0.1202 +0.0001 +0.2133 +0.1649 +0.0814 +0.0764 +0.1615 +0.0042 +0.0122 +0.0002 +0.9742 +0.2932 +0.0083 +0.0469 +0.0774 +0.0155 +0.0014 +0.0045 +0.0012 +0.0062 +0.0056 +0.0165 +0.0086 +0.028 +0.2173 +0.0098 +0.0069 +0.2004 +0.2936 +0.1673 +0.0077 +0.3919 +0.0947 +0.1318 +0.9237 +0.7773 +0.8709 +0.053 +0.7516 +0.7981 +0.4771 +0.46 +0.0232 +0.0235 +0.8979 +0.0501 +0.2007 +1.2686 +0.0048 +0.369 +0.3234 +0.0498 +0.9678 +0.0414 +0.2904 +0.0342 +0.0472 +0.2298 +0.2353 +0.0541 +0.0128 +0.0114 +0.0051 +0.0109 +0.0039 +0.054 +0.1148 +0.113 +0.0053 +0.0006 +0.0153 +0.3651 +0.0386 +0.0079 +0.0049 +0.1929 +0.0489 +0.1104 +0.0084 +0.1168 +0.0511 +0.0095 +0.0174 +0.796 +0.0882 +0.0196 +0.8069 +0.0756 +0.1724 +0.0991 +0.2114 +0.0211 +0.5807 +0.1063 +0.0004 +0.0106 +0.0886 +0.3915 +0.208 +0.0098 +0.2239 +0.014 +0.3423 +0.2942 +0.1428 +0.2643 +0.6607 +0.0858 +0.7548 +1.0773 +0.2518 +0.1133 +0.0543 +0.001 +0.1813 +0.0908 +0.3359 +0.1742 +0.0292 +0 +0.0878 +0.031 +0.2581 +0.0598 +0.2773 +0.0757 +0.8633 +0.2916 +0.0047 +0.05 +0.0692 +1.0165 +0.4004 +0.063 +0.0297 +0.0463 +0.0009 +0.0727 +0.0104 +0.036 +0.0131 +0.0029 +0.0099 +0.0133 +0.037 +0.001 +0.0995 +0.2957 +0.0048 +0.0279 +0.0046 +0.0451 +0.0055 +0.0562 +0.0182 +0.2682 +0.0921 +0.051 +0.223 +0.0175 +0.0263 +0.0043 +0.8182 +0.0284 +0.1436 +0.0039 +0.0132 +0.0035 +0.0056 +0.0184 +0.0005 +0.0006 +0.0017 +0.0018 +0.0053 +0.0491 +0.0256 +0.0017 +0.0022 +0.0027 +0.0005 +0.0012 +0.0059 +0.0153 +0.2199 +0.2533 +0.6507 +0.2872 +0.2587 +0.0314 +0.0478 +0.0188 +0.0634 +0.0148 +0.0695 +0.3773 +0.181 +0.0777 +0.1711 +0.0414 +0.954 +0.1138 +0.1519 +0.618 +0.306 +0.0237 +0.4824 +0.7117 +0 +0.2937 +0.3689 +0.1966 +0.0913 +0.2928 +0.0493 +0.53 +0.2942 +0.6487 +0.4588 +0.2235 +0.7255 +0.003 +0.2727 +0.1651 +0.1325 +0.0316 +0.0122 +0.1692 +0.047 +0.0368 +0.062 +0.1961 +0.0343 +0.1782 +0.0479 +0.0147 +0.5828 +0.6437 +0.2547 +0.2722 +0.006 +0.0035 +0.001 +0.7069 +0.561 +0.263 +0.4407 +0.1208 +0.0132 +0.0247 +0.5474 +0.231 +0.4161 +1.1778 +1.1076 +0.0148 +0.0887 +0.0294 +0.0777 +0.2194 +0.0052 +0.0311 +0.0946 +0.0511 +0.1514 +0.0651 +0.0165 +0.1239 +0.0657 +0.2045 +0.0376 +0.2265 +0.0094 +0.2368 +0.0062 +0.0448 +0.2849 +0.2765 +0.1022 +0.237 +0.0444 +0.0124 +0.0171 +0.0359 +0.0138 +0.018 +0.0681 +0.0003 +0.0583 +0.4501 +0.4459 +0.0572 +0.1132 +0.0088 +0.2459 +0.2737 +0.4208 +0.9762 +0.0137 +0.1052 +0.6842 +0.2124 +0.2212 +0.4269 +0.2024 +0.0051 +0.0102 +0.1179 +0.0107 +0.2124 +0.0594 +0.2906 +0.1911 +0.1137 +0.1467 +0.0096 +0.4364 +0.4422 +0.1101 +0.1203 +0.5172 +0.5233 +0.1255 +0.0216 +0.0681 +0.0245 +0.115 +0.0311 +0.0431 +0.0571 +0.0692 +0.1173 +0.1987 +0.3054 +0.18 +0.1021 +0.2048 +0.0015 +0.0119 +0.0042 +0.0086 +0.0206 +0.0023 +0.0028 +0.0019 +0.0006 +0.0003 +0.005 +0.0086 +0.0084 +0.0028 +0.0076 +0.0039 +0.0018 +0.0067 +0.0075 +0.0021 +0.0126 +0.0082 +0.0072 +0.0008 +0.0069 +0.0014 +0.0004 +0.0054 +0.0065 +0.0005 +0.0525 +0.0195 +0.0242 +0.0318 +0.0202 +0.09 +0.0182 +0.0239 +0.037 +0.0119 +0.0096 +0.0001 +0.0026 +0.0072 +0.0116 +0.024 +0.0048 +0.0016 +0.0035 +0.0007 +0.0027 +0.3567 +0.1611 +0.0209 +0.4773 +0.0336 +0.0176 +0.0043 +0.0277 +0.0475 +0.0227 +0.0175 +0.004 +0.0321 +0.0343 +0.0245 +0.0017 +0.0132 +0.0002 +0.0027 +0.0025 +0.0085 +0.0288 +0.0253 +0.0063 +0.0178 +0.0267 +0.0085 +0.0108 +0.0209 +0.0498 +0.0427 +0.0009 +0.0361 +0.0065 +0.0515 +0.0075 +0.0097 +0.0159 +0.0021 +0.0025 +0.0059 +0.0005 +0.0013 +0.0068 +0.011 +0.0073 +0.0144 +0.0073 +0.0104 +0.0007 +0.0023 +0.0015 +0.0031 +0.0064 +0.0036 +0.0152 +0.0167 +0.0163 +0.0526 +0.0803 +0.0927 +0.0053 +0.0102 +0.0076 +0.0507 +0.0211 +0.0123 +0.0103 +0.0143 +0.0092 +0.0649 +0.0066 +0.0413 +0.1123 +0.1436 +0.0078 +0.0266 +0.0017 +0.1005 +0.0707 +0.053 +0.0067 +0.0023 +0.0026 +0.0303 +0.001 +0.0412 +0.0178 +0.0127 +0.0148 +0.0583 +0.0103 +0.0167 +0.2566 +0.0252 +0.0227 +0.0294 +0.0331 +0.148 +0.0735 +0.0058 +0.0116 +0.0049 +0.051 +0.0368 +0.0499 +0.0526 +0.0095 +0.006 +0.016 +0.0136 +0.0012 +0.014 +0.0188 +0.0044 +0.042 +0.021 +0.0124 +0.0119 +0.0013 +0.0163 +0.0102 +0.0132 +0.0247 +0.0012 +0.0125 +0.0011 +0.0033 +0.0016 +0.0035 +0.0004 +0.0057 +0.0119 +0.0001 +0.0189 +0.0034 +0.284 +0.0255 +0.1166 +0.1113 +0.1182 +0.0941 +0.0337 +0.048 +0.02 +0.0463 +0.0333 +0.0171 +0.0031 +0.0888 +0.0015 +0.1029 +0.1438 +0.0249 +0.4599 +0.0713 +0.0027 +0.0029 +0.0285 +0.0107 +0.0441 +0.0021 +0.0188 +0.1101 +0.3323 +0.0277 +0.0485 +0.911 +0.0116 +0.0367 +0.0452 +0.0368 +0.0393 +0.057 +0.0085 +0.0096 +0.2232 +0.0014 +0.0034 +0.0043 +0.003 +0.0447 +0.0028 +0.2121 +0.0338 +0.2434 +0.257 +0.0278 +1.0679 +0.8036 +1.0677 +0.0001 +0.0069 +0.0006 +0.0167 +0.0218 +0.0243 +0.0004 +0.0012 +0.0017 +0.0002 +0.0002 +0.0008 +0.0002 +0.0008 +0.0002 +0.0014 +0.0001 +0.152 +0.0005 +0.0011 +0.0003 +0.1604 +0.0009 +0.159 +0.0001 +0.1432 +0.0001 +0.1428 +0 +0 +0 +0.0001 +0.133 +0.0111 +0.4371 +0.2968 +0.2589 +0.004 +0.1907 +0.1492 +0.2227 +0.1577 +0.1782 +0.0831 +0.3441 +0.0742 +0.1865 +0.0662 +0.0556 +0.2523 +0.0919 +0.081 +0.1057 +0.0486 +0.0835 +0.1038 +0.0634 +0.089 +0.1439 +0.0732 +0.0909 +0.0663 +0.0756 +0.0463 +0.2758 +0.1715 +0.6578 +0.0759 +0.0769 +0.0652 +0.2817 +0.0657 +0.0892 +0.1684 +0.1139 +0.8142 +0.9675 +0.1004 +0.0615 +0.024 +0.0676 +0.0511 +0.0346 +0.0735 +0.0033 +0.0063 +0.104 +0.1275 +0.1404 +0.0405 +0.026 +0.1268 +0.0005 +0.0454 +0.0476 +0.1649 +0.1384 +0.0158 +0.2079 +0.3019 +0.4259 +0.4727 +0.5258 +0.0093 +0.0141 +0.1413 +0.5589 +0.0122 +0.0396 +0.0191 +0.1646 +0.0281 +0.2123 +0.1363 +0.326 +0.0297 +0.0228 +0.0067 +0.0007 +0.0202 +0.0343 +0.027 +0.0135 +0.0237 +0.253 +0.0045 +0.0103 +0.0238 +0.1159 +0.0738 +0.1722 +0.2984 +0.2728 +0.0002 +0.1148 +0.0299 +0.0037 +0 +0.0002 +0.0001 +0.0001 +0.0021 +0.0003 +0.0006 +0.0007 +0.0022 +0.0005 +0.0029 +0.0004 +0.0015 +0.0019 +0 +0.0011 +0.0019 +0.001 +0.0004 +0 +0.0001 +0.0006 +0.0643 +0.0159 +0.0203 +0.1292 +0.0068 +0.0137 +0.0124 +0.0146 +0.0089 +0.0064 +0.0019 +0.0001 +0.0047 +0.0224 +0.0002 +0.015 +0.003 +0.0025 +0.0081 +0.0283 +0.0024 +0.0007 +0.0054 +0.1248 +0.2207 +0.2432 +0.0023 +0.0655 +0.1316 +0.1953 +0.0985 +0.0369 +0.0479 +0.0248 +0.0666 +0.0156 +0.0345 +0.0152 +0.0307 +0.0265 +0.0981 +0.0517 +0.0152 +0.0755 +0.0211 +0.0587 +0.0528 +0.1012 +0.2416 +0.8667 +0 +0.0507 +0.0325 +0 +0.003 +0 +0.0251 +0.01 +0.1325 +0.0199 +0.0191 +0.0376 +0.0294 +0 +0 +0.0448 +0.003 +0.0492 +0.0201 +0.0162 +0.0031 +0.0874 +0.019 +0.0547 +0.0833 +0.0828 +0.0033 +0.0099 +0.0029 +0.0019 +0.026 +0.0174 +0.0016 +0.0025 +0.1452 +0.0636 +0.2076 +0.0003 +0.0023 +0.0038 +0.0162 +0.1901 +0.0235 +0.4981 +0.307 +0.0334 +0.395 +0.2894 +0.097 +0.3307 +0.0702 +0.073 +0.0271 +0.2509 +0.0595 +0.0069 +0.1225 +0.0658 +0.0938 +0.1822 +0.1839 +0.0542 +0.0021 +0.0001 +0.0017 +0 +0 +0.0516 +0.0572 +0.0001 +0.0426 +0 +0 +0.0006 +0.0026 +0.0181 +0.0027 +0.0473 +0.0312 +0.0146 +0 +0.0052 +0.1366 +0.0127 +0 +0 +0.0592 +0.1341 +0.5065 +0.2117 +0.0008 +0.0794 +0.3656 +0.2701 +0.0162 +0.0025 +0.009 +0.0067 +0.0012 +0.1309 +0.0044 +0.0343 +0.0029 +0.0589 +0.0477 +0.3482 +0.096 +0.1166 +0.1831 +0.0114 +0.6698 +0.0019 +0.0165 +0.0268 +0.05 +0.0403 +0.2757 +0.3092 +0.3416 +0.416 +0 +0 +1.0447 +0.0138 +0.0462 +0.0218 +0.0538 +0.2595 +0.2868 +0.0017 +0.6913 +0.0773 +0.0005 +0.0254 +0.0347 +0.6905 +0.1895 +0.6881 +0.4335 +0.7393 +0.4429 +0.1447 +1.0473 +0.898 +1.4591 +1.4323 +0.4252 +0.0427 +0.031 +0.0041 +0.0156 +0.0011 +0.0047 +0.024 +0.0095 +0.0133 +0.0092 +0.0045 +0.0079 +0.23 +0.0068 +0.0195 +0.2219 +0.3287 +0.0156 +0.0032 +0.0751 +0.0156 +0.0103 +0.0906 +0.0124 +0.0267 +0.008 +0.0075 +0.0451 +0.6158 +0.0497 +0.0016 +0.0007 +0.1753 +0.0158 +0.0226 +0.0877 +0.0058 +0 +0.0021 +0.0018 +0.0025 +0.0043 +0.006 +0.0279 +0.1983 +0.0537 +0.0011 +0.0067 +0.0009 +0.0018 +0.0027 +0.0018 +0.0071 +0.0187 +0.0726 +0.0843 +0.0004 +0.0614 +0.0057 +0.0323 +0.0001 +0.0323 +0.001 +0.0166 +0.0001 +0.0733 +0.0328 +0.0014 +0.0127 +0.0295 +0.0043 +0.3892 +0.0133 +0.052 +0.0001 +0.1103 +0.0234 +0.0012 +0.0048 +0.0226 +0.0334 +0.0053 +0.0127 +0.0288 +0.0017 +0.0037 +0.0241 +0.0153 +0.0032 +0.0049 +0.0004 +0.1015 +0.239 +0.3593 +0.0308 +0.0807 +0.1463 +0.0922 +0.2375 +0.1907 +0.0653 +0.0267 +0.0366 +0.0687 +0.0415 +0.0964 +0.0675 +0.0054 +0.0432 +0.021 +0.0222 +0.0328 +0.0171 +0.0453 +0.0124 +0.0205 +0.008 +0.0235 +0.0145 +0.0015 +0.0186 +0.0285 +0.0033 +0.039 +0.2408 +0.6361 +0.4447 +0.3936 +0.0295 +0.6065 +0.0723 +0.0486 +0.0062 +0.0086 +0.1296 +0.0889 +0.1744 +0.196 +0.0842 +0.0521 +0.2024 +0.2001 +1.1131 +0.7926 +0 +0.2407 +0.0066 +0 +0.2248 +0.7858 +0.0046 +0.0557 +0.0062 +0.0001 +0.007 +0.0101 +0.0052 +0.0001 +0.0959 +0.0354 +0.0439 +0.0085 +0.034 +0.0118 +0.225 +0.0502 +0.0221 +0.0244 +0.0442 +0.0022 +0.0014 +1.0188 +0.007 +0.0243 +0.0018 +0.0038 +0.0046 +0.0078 +0 +0.0036 +0.0003 +0.0185 +0.0034 +0.0001 +0.0002 +0.1379 +0.3619 +0.2683 +0.1674 +0.0214 +0.003 +0.067 +0.0613 +0.1069 +0.0015 +0.0088 +0.1441 +0.1263 +0.1006 +0.0074 +0.0584 +0.0009 +0.0169 +0.0509 +0.0443 +0.0154 +0.0008 +0.0008 +0.6591 +0.5771 +0.9451 +0.6374 +0.8197 +0.3868 +0.1255 +0.034 +0.124 +0.2648 +0.486 +0.3462 +0.4529 +0.6425 +0.4247 +0.0029 +0.1847 +0.0342 +0.0073 +0.0555 +0.1115 +0.036 +0.0664 +0.0085 +0.0105 +0.0218 +0.0086 +0.0018 +0.0054 +0.0008 +0.001 +0.0008 +0.0056 +0.0007 +0.0018 +0.0156 +0.0008 +0.0721 +0.0007 +0.0034 +0.0021 +0.0008 +0.0003 +0.0478 +0.0004 +0.0002 +0.0005 +0.0113 +0.0378 +0.0041 +0.0025 +0.0028 +0.0154 +0.0021 +0.0071 +0.0013 +0.0028 +0.005 +0.0143 +0.0009 +0.0107 +0 +0.0003 +0 +0 +0.0043 +0.0021 +0.0002 +0 +0.0001 +0.0571 +0 +0.0266 +0.0147 +0.2823 +0.0561 +0.006 +0.0407 diff --git a/examples/tadf/TADF_f/f.py b/examples/tadf/TADF_f/f.py new file mode 100644 index 000000000..40d8b54ec --- /dev/null +++ b/examples/tadf/TADF_f/f.py @@ -0,0 +1,25 @@ +import hydra +from f_model import eval +from f_model import featurize_molecules +from f_model import load_data +from f_model import train +from omegaconf import DictConfig + + +@hydra.main(version_base=None, config_path="./config", config_name="f.yaml") +def main(cfg: DictConfig): + + data, smis = load_data(cfg) + + X = featurize_molecules(smis) + + if cfg.mode == "train": + train(cfg, X, data) + elif cfg.mode == "eval": + eval(cfg, X, data) + else: + raise ValueError(f"cfg.mode should be 'train'or 'eval', but got '{cfg.mode}'") + + +if __name__ == "__main__": + main() diff --git a/examples/tadf/TADF_f/f_model.py b/examples/tadf/TADF_f/f_model.py new file mode 100644 index 000000000..943b20909 --- /dev/null +++ b/examples/tadf/TADF_f/f_model.py @@ -0,0 +1,183 @@ +import os + +import matplotlib.pyplot as plt +import numpy as np +import paddle +import rdkit.Chem as Chem +from omegaconf import DictConfig +from rdkit.Chem import rdFingerprintGenerator +from sklearn.decomposition import PCA +from sklearn.metrics import r2_score +from sklearn.model_selection import train_test_split + +import ppsci + +os.environ["HYDRA_FULL_ERROR"] = "1" +os.environ["KMP_DUPLICATE_LIB_OK"] = "True" +plt.rcParams["axes.unicode_minus"] = False +plt.rcParams["font.sans-serif"] = ["DejaVu Sans"] + +# 加载数据集 +def load_data(cfg): + data_dir = cfg.data_dir + sim_dir = cfg.sim_dir + f_dat_path = os.path.join(data_dir) + smis_txt_path = os.path.join(sim_dir) + + data = [] + with open(f_dat_path) as f: + for line in f: + num = float(line.strip()) + data.append(num) + smis = [] + with open(smis_txt_path) as f: + for line in open("./smis.txt"): + smis.append(line.strip()) + + return data, smis + + +def featurize_molecules(smis): + vectors = [] + del_mol = [] + for s in smis: + mol = Chem.MolFromSmiles(s) + try: + generator = rdFingerprintGenerator.GetMorganGenerator(radius=2, fpSize=2048) + fp = generator.GetFingerprint(mol) + _input = np.array(list(map(int, fp.ToBitString()))) + vectors.append(_input) + except Exception as e: + print(f"Error processing {s}: {e}") + del_mol.append(s) + pca = PCA(n_components=0.99) + pca.fit(vectors) + X = paddle.to_tensor(pca.transform(vectors)) + return X + + +def train(cfg: DictConfig, X, data): + # 划分数据集 + def k_fold(k, i, X, Y): + fold_size = tuple(X.shape)[0] // k + val_start = i * fold_size + if i != k - 1: + val_end = (i + 1) * fold_size + x_val, y_val = X[val_start:val_end], Y[val_start:val_end] + x_train = np.concatenate((X[0:val_start], X[val_end:]), axis=0) + y_train = np.concatenate((Y[0:val_start], Y[val_end:]), axis=0) + else: + x_val, y_val = X[val_start:], Y[val_start:] + x_train = X[0:val_start] + y_train = Y[0:val_start] + return x_train, y_train, x_val, y_val + + Y = paddle.to_tensor(data) + x_train, y_train, x_test, y_test = k_fold(cfg.TRAIN.k, cfg.TRAIN.i, X, Y) + # 处理数据集 + x_train = paddle.to_tensor(x_train, dtype="float32") + x = { + "key_{}".format(i): paddle.unsqueeze( + paddle.to_tensor(x_train[:, i], dtype="float32"), axis=1 + ) + for i in range(x_train.shape[1]) + } + y_train = paddle.unsqueeze(paddle.to_tensor(y_train, dtype="float32"), axis=1) + + # 构建约束 + bc_sup = ppsci.constraint.SupervisedConstraint( + dataloader_cfg={ + "dataset": { + "input": x, + "label": {"u": y_train}, + "name": "IterableNamedArrayDataset", + }, + "batch_size": cfg.TRAIN.batch_size, + }, + loss=ppsci.loss.MSELoss("mean"), + name="bc_sup", + ) + # 设置模型 + hidden_size = [587, 256] + num_layers = None + + # 实例化模型 + model = ppsci.arch.TADF( + input_keys=tuple(x.keys()), + hidden_size=hidden_size, + num_layers=num_layers, + **cfg.MODEL, + ) + optimizer = ppsci.optimizer.optimizer.Adam( + cfg.TRAIN.learning_rate, + beta1=(0.9, 0.99)[0], + beta2=(0.9, 0.99)[1], + weight_decay=cfg.TRAIN.weight_decay, + )(model) + # 构建Solver + solver = ppsci.solver.Solver( + model, + constraint={ + "bc_sup": bc_sup, + }, + optimizer=optimizer, + epochs=cfg.TRAIN.epochs, + eval_during_train=False, + iters_per_epoch=cfg.TRAIN.iters_per_epoch, + seed=cfg.seed, + ) + try: + solver.train() + except Exception as ex: + print(ex) + paddle.save(model.state_dict(), cfg.TRAIN.save_model_path) + + +# 进行测试 +def eval(cfg: DictConfig, X, data): + y = paddle.to_tensor(data) + # 重新划分数据集 + x_train, x_test, y_train, y_test = train_test_split( + X.numpy(), y.numpy(), test_size=cfg.EVAL.test_size, random_state=cfg.EVAL.seed + ) + x = { + "key_{}".format(i): paddle.unsqueeze( + paddle.to_tensor(x_test[:, i], "float32"), axis=1 + ) + for i in range(x_test.shape[1]) + } + hidden_size = [587, 256] + num_layers = None + model = ppsci.arch.TADF( + input_keys=tuple(x.keys()), + hidden_size=hidden_size, + num_layers=num_layers, + **cfg.MODEL, + ) + model.set_state_dict(paddle.load(cfg.EVAL.load_model_path)) + ytest = paddle.unsqueeze(paddle.to_tensor(y_test, dtype="float32"), axis=1) + ypred = model(x) + ytest = {"u": ytest} + + # 计算损失 + loss = ppsci.metric.MAE() + MAE = loss(ypred, ytest).get("u").numpy() + loss = ppsci.metric.RMSE() + RMSE = loss(ypred, ytest).get("u").numpy() + ypred = ypred.get("u").numpy() + ytest = ytest.get("u").numpy() + R2 = r2_score(ytest, ypred) + print("MAE", MAE) + print("RMSE", RMSE) + print("R2", R2) + + # 可视化 + plt.scatter(ytest, ypred, s=15, color="royalblue", marker="s", linewidth=1) + plt.plot([ytest.min(), ytest.max()], [ytest.min(), ytest.max()], "r-", lw=1) + plt.legend(title="R²={:.3f}\n\nMAE={:.3f}".format(R2, MAE)) + plt.xlabel("Test f") + plt.ylabel("Predicted f") + save_path = "test_f.png" + plt.savefig(save_path) + print(f"图片已保存至：{save_path}") + plt.show() diff --git a/examples/tadf/TADF_f/smis.txt b/examples/tadf/TADF_f/smis.txt new file mode 100644 index 000000000..06fd4771c --- /dev/null +++ b/examples/tadf/TADF_f/smis.txt @@ -0,0 +1,5136 @@ +c1cc(-c2c3ccoc3cc3ccoc23)n[nH]1 +c1cc(-c2c3cc[nH]c3cc3occc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c3cc[nH]c3cc3occc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2c3cc[nH]c3cc3occc23)c2[nH]nnc2c1 +c1cc(-c2c3ncoc3cc3ncoc23)c2c(c1)cnc1ccccc12 +c1cc(-c2c3ncoc3nc3ocnc23)c2nn[nH]c2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2scnc2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2[nH]c3ccncc3c2c1 +c1cc(-c2c3ncoc3nc3ocnc23)c2[nH]ccc2c1 +c1cc(-c2c3ncoc3nc3ocnc23)cnn1 +c1cc(-c2c3ncsc3cc3ncsc23)c2ncoc2c1 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2c(c1)sc1ncccc12 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2ccoc2c1 +c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2c(c1)cnc1ccccc12 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2ocnc2c1 +c1cc(-c2c3[nH]ccc3cc3ccoc23)c2[nH]nnc2c1 +c1cc(-c2c3[nH]cnc3cc3nc[nH]c23)c2[nH]nnc2c1 +c1cc(-c2c3[nH]cnc3cc3nc[nH]c23)[nH]n1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cc3cccnc3c3ncccc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cc3[nH]ccc3cn2)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccc3c(c2)[nH]c2cnccc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cccc3cnc4ccccc4c23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cccc3ocnc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2ccnc3c2ccc2cccnc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2cncc3[nH]c4ccccc4c23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2coc3cc4ccoc4cc23)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-c2nc3cc4ncoc4nc3o2)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)cc(-n2cnc3cc4nc[nH]c4cc32)c1 +c1cc(-c2cc3c4c(c2)CCCN4CCC3)ccc1-c1cnoc1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2nccnc2c1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2sccc2c1 +c1cc(-c2cc3cc4ccoc4cc3[nH]2)c2[nH]c3cnccc3c2c1 +c1cc(-c2cc3cc4cc[nH]c4cc3o2)c2ocnc2c1 +c1cc(-c2cc3cc4cc[nH]c4cc3o2)c2[nH]nnc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2ncsc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2occc2c1 +c1cc(-c2cc3cc4occc4cc3o2)c2ocnc2c1 +c1cc(-c2cc3cnccc3[nH]2)c2nn[nH]c2c1 +c1cc(-c2cc3cnccc3[nH]2)c2occc2c1 +c1cc(-c2cc3cnccc3[nH]2)c2[nH]c3ccncc3c2c1 +c1cc(-c2cc3cnccc3[nH]2)c2[nH]nnc2c1 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2[nH]c3ccncc3c2c1 +c1cc(-c2cc3nc4ccoc4nc3[nH]2)c2[nH]ccc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2ccoc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2ccsc2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)c2cc[nH]c2c1 +c1cc(-c2cc3nc4cc[nH]c4nc3o2)n[nH]1 +c1cc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c2nccnc2c1 +c1cc(-c2cc3[nH]c4ccccc4c3cn2)c2nccnc2c1 +c1cc(-c2cc3[nH]c4ccccc4c3cn2)c2sccc2c1 +c1cc(-c2cc3[nH]c4ccncc4c3cn2)c2ccoc2c1 +c1cc(-c2cc3[nH]ccc3cn2)c2c(c1)sc1ncccc12 +c1cc(-c2cc3[nH]ccc3cn2)c2ncoc2c1 +c1cc(-c2cc3[nH]ccc3cn2)c2nn[nH]c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2cc[nH]c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2ncsc2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ccc(-c3cnccn3)cc2)c2[nH]nnc2c1 +c1(c2nccnc2)cccc(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +c1cc(-c2ccc3c(c2)c2ccccc2c2nccnc32)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)c2[nH]nnc2c1 +c1cc(-c2ccc3c(c2)ncc2ccccc23)c2occc2c1 +c1cc(-c2ccc3c(c2)oc2ccccc23)c2nn[nH]c2c1 +c1cc(-c2ccc3c(c2)oc2ncccc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c(c2)sc2ccccc23)c2ccoc2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2nn[nH]c2c1 +c1cc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c2[nH]nnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)cc(-c2cnccn2)c1 +c1cc(-c2ccc3c(c2)[nH]c2ccncc23)c2ocnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ccsc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2cc[nH]c2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2nccnc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ncoc2c1 +c1cc(-c2ccc3c(c2)[nH]c2cnccc23)c2ocnc2c1 +c1cc(-c2ccc3c(cnc4ccccc43)c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(cnc4ccccc43)c2)c2occc2c1 +c1cc(-c2ccc3c(n2)sc2ncccc23)c2nccnc2c1 +c1cc(-c2ccc3c(n2)sc2ncccc23)c2[nH]nnc2c1 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2cc[nH]c2c1 +c1cc(-c2ccc3c(n2)[nH]c2ccccc23)c2sccc2c1 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2nccnc2c1 +c1cc(-c2ccc3c4c2CCCN4CCC3)c2[nH]nnc2c1 +c1cc(-c2ccc3c4ccccc4c4nccnc4c3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3c4ccccc4c4nccnc4c3c2)c2ccsc2c1 +c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)c2sccc2c1 +c1cc(-c2ccc3ccc4cccnc4c3n2)c2[nH]ccc2c1 +c1cc(-c2ccc3ccoc3c2)no1 +c1cc(-c2ccc3ccsc3c2)c2ccoc2c1 +c1cc(-c2ccc3cc[nH]c3c2)c2ncoc2c1 +c1cc(-c2ccc3cc[nH]c3c2)c2nn[nH]c2c1 +c1cc(-c2ccc3cnc4ccccc4c3c2)c2scnc2c1 +c1cc(-c2ccc3cnc4ccccc4c3c2)c2[nH]ccc2c1 +c1cc(-c2ccc3ncc4ccccc4c3c2)c2occc2c1 +c1cc(-c2ccc3ncccc3n2)c2[nH]ccc2c1 +c1cc(-c2ccc3nccnc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3nccnc3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3ncoc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3ncoc3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3ncoc3c2)c2ccoc2c1 +c1cc(-c2ccc3ncoc3c2)c2cc[nH]c2c1 +c1cc(-c2ccc3ncsc3c2)c2sccc2c1 +c1cc(-c2ccc3nn[nH]c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3nn[nH]c3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3oc4ccccc4c3c2)c2nn[nH]c2c1 +c1cc(-c2ccc3oc4ncccc4c3c2)c2ncoc2c1 +c1cc(-c2ccc3oc4ncccc4c3c2)c2ocnc2c1 +c1cc(-c2ccc3occc3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3ocnc3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3ocnc3c2)c2ncsc2c1 +c1cc(-c2ccc3ocnc3c2)c2occc2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2ccc3sc4ccccc4c3c2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3sc4ccccc4c3c2)c2cc[nH]c2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2ncoc2c1 +c1cc(-c2ccc3sc4ccccc4c3c2)c2[nH]nnc2c1 +c1cc(-c2ccc3sccc3c2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccc3sccc3c2)c2ncoc2c1 +c1cc(-c2ccc3sccc3c2)c2sccc2c1 +c1cc(-c2ccc3sccc3c2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ccc3sccc3c2)c2[nH]ccc2c1 +c1cc(-c2ccc3sccc3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3scnc3c2)c2ocnc2c1 +c1cc(-c2ccc3scnc3c2)no1 +c1cc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)cc(-c2cnccn2)c1 +c1cc(-c2ccc3[nH]c4ccncc4c3c2)c2[nH]nnc2c1 +c1cc(-c2ccc3[nH]c4cnccc4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ccoc2c1 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ncsc2c1 +c1cc(-c2ccc3[nH]c4ncccc4c3c2)c2ocnc2c1 +c1cc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2ccc3[nH]nnc3c2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccc3[nH]nnc3c2)c2ncoc2c1 +c1cc(-c2ccc3[nH]nnc3c2)c2scnc2c1 +c1cc(-c2cccc3c2cnc2ccccc23)c2ocnc2c1 +c1cc(-c2cccc3c2oc2ccccc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3c2oc2ccccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3c2sc2ncccc23)c2nn[nH]c2c1 +c1cc(-c2cccc3c2sc2ncccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c2nccnc2c1 +c1cc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c2ocnc2c1 +c1cc(-c2cccc3c2[nH]c2ccncc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3c2[nH]c2ccncc23)c2ocnc2c1 +c1cc(-c2cccc3c2[nH]c2cnccc23)c2scnc2c1 +c1cc(-c2cccc3c2[nH]c2cnccc23)c2[nH]c3cnccc3c2c1 +c1cc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)c2nccnc2c1 +c1cc(-c2cccc3c4ccccc4c4nccnc4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c2nccnc2c1 +c1cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c2ncoc2c1 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2ccsc2c1 +c1cc(-c2cccc3c4nccnc4c4ccccc4c23)c2nn[nH]c2c1 +c1cc(-c2cccc3ccsc23)c2[nH]ccc2c1 +c1cc(-c2cccc3ncoc23)c2nccnc2c1 +c1cc(-c2cccc3ncsc23)c2nccnc2c1 +c1cc(-c2cccc3nn[nH]c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3oc4ccccc4c23)c2sccc2c1 +c1cc(-c2cccc3oc4ncccc4c23)c2nccnc2c1 +c1cc(-c2cccc3oc4ncccc4c23)c2sccc2c1 +c1cc(-c2cccc3ocnc23)c2ccoc2c1 +c1cc(-c2cccc3ocnc23)c2occc2c1 +c1cc(-c2cccc3sc4ncccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3sc4ncccc4c23)c2ocnc2c1 +c1cc(-c2cccc3sccc23)c2ccsc2c1 +c1cc(-c2cccc3scnc23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3scnc23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2cccc3[nH]c4cnccc4c23)c2occc2c1 +c1cc(-c2cccc3[nH]c4ncccc4c23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c2nccnc2c1 +c1cc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c2nn[nH]c2c1 +c1cc(-c2cccc3[nH]ccc23)c2ocnc2c1 +c1cc(-c2cccc3[nH]ccc23)c2[nH]nnc2c1 +c1cc(-c2cccc3[nH]nnc23)c2occc2c1 +c1cc(-c2ccnc3c2ccc2cccnc23)c2[nH]ccc2c1 +c1cc(-c2ccnc3cccnc23)c2[nH]ccc2c1 +c1cc(-c2ccnc3ncccc23)c2scnc2c1 +c1cc(-c2ccnc3oc4ccccc4c23)c2sccc2c1 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)cnc1ccccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2c(c1)[nH]c1ncccc12 +c1cc(-c2ccnc3sc4ncccc4c23)c2ncoc2c1 +c1cc(-c2ccnc3[nH]c4ccccc4c23)c2[nH]ccc2c1 +c1cc(-c2ccnnc2)c2sccc2c1 +c1cc(-c2ccno2)c2c(c1)oc1ncccc12 +c1cc(-c2ccno2)c2c(c1)sc1ncccc12 +c1cc(-c2ccno2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ccno2)[nH]n1 +c1cc(-c2ccn[nH]2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ccon2)c2ccoc2c1 +c1cc(-c2ccon2)c2nn[nH]c2c1 +c1cc(-c2ccon2)n[nH]1 +c1cc(-c2cc[nH]n2)c2ccsc2c1 +c1cc(-c2cc[nH]n2)c2ncoc2c1 +c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c2c(c1)[nH]c1ncccc12 +c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c2ocnc2c1 +c1cc(-c2cnc3ccccc3n2)c2c(c1)cnc1ccccc12 +c1cc(-c2cnc3nccnc3n2)c2ccoc2c1 +c1cc(-c2cnc3nccnc3n2)c2ncoc2c1 +c1cc(-c2cnc3nccnc3n2)c2[nH]c3cnccc3c2c1 +c1cc(-c2cnc3oc4ccccc4c3c2)c2sccc2c1 +c1cc(-c2cnc3oc4ccccc4c3c2)c2[nH]nnc2c1 +c1cc(-c2cnc3sc4ccccc4c3c2)c2c(c1)cnc1ccccc12 +c1cc(-c2cnc3sc4ncccc4c3c2)c2nn[nH]c2c1 +c1cc(-c2cnc3sc4ncccc4c3c2)cc(-c2cnccn2)c1 +c1cc(-c2cncc3c2[nH]c2ccncc23)c2c(c1)sc1ncccc12 +c1cc(-c2cncc3cc[nH]c23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2cncc3cc[nH]c23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cncc3cc[nH]c23)c2ncsc2c1 +c1cc(-c2cncc3cc[nH]c23)c2[nH]c3ccncc3c2c1 +c1cc(-c2cncc3cc[nH]c23)c2[nH]nnc2c1 +c1cc(-c2cncc3[nH]c4ccccc4c23)c2[nH]ccc2c1 +c1cc(-c2cnccn2)cc(-c2cc3ccccc3s2)c1 +c1cc(-c2cnccn2)cc(-c2cc3ccccc3[nH]2)c1 +c1cc(-c2cnccn2)cc(-c2cc3nc4ccoc4nc3[nH]2)c1 +c1cc(-c2cnccn2)cc(-c2cccc3ncc4ccccc4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3oc4ncccc4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3sccc23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c1 +c1cc(-c2cnccn2)cc(-c2cccc3[nH]ccc23)c1 +c1cc(-c2cnccn2)cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +c1cc(-c2cnccn2)cc(-c2coc3cc4ccoc4cc23)c1 +c1cc(-c2cnccn2)cc(-c2c[nH]c3nc4occc4nc23)c1 +c1cc(-c2cnccn2)cc(-c2nccc3[nH]c4ccncc4c23)c1 +c1cc(-c2cnccn2)cc(-n2c3ccccc3c3c4ccccc4[nH]c32)c1 +c1cc(-c2cnccn2)cc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c1 +c1cc(-c2cnccn2)cc(-n2ccc3cc4ccoc4cc32)c1 +c1cc(-c2cnccn2)cc(-n2cnc3c4ccccc4c4ccccc4c32)c1 +c1cc(-c2cncs2)c2[nH]ccc2c1 +c1cc(-c2cnoc2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2cnoc2)c2ccoc2c1 +c1cc(-c2cnoc2)[nH]n1 +c1cc(-c2cn[nH]c2)c2c(c1)cnc1ccccc12 +c1cc(-c2cn[nH]c2)c2[nH]nnc2c1 +c1cc(-c2cn[nH]c2)on1 +c1cc(-c2coc3cc4ccoc4cc23)c2c(c1)cnc1ccccc12 +c1cc(-c2coc3cc4ccoc4cc23)no1 +c1cc(-c2coc3cc4[nH]ccc4cc23)c2ocnc2c1 +c1cc(-c2coc3cc4[nH]ccc4cc23)c2[nH]nnc2c1 +c1cc(-c2coc3ccccc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2coc3ccccc23)c2sccc2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2cc[nH]c2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2ncsc2c1 +c1cc(-c2coc3nc4[nH]ccc4nc23)c2scnc2c1 +c1cc(-c2csc3ccccc23)c2ncoc2c1 +c1cc(-c2c[nH]c3cc4occc4cc23)c2ocnc2c1 +c1cc(-c2c[nH]c3cc4occc4cc23)no1 +c1cc(-c2c[nH]c3ccccc23)c2sccc2c1 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)oc1ncccc12 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)[nH]c1ccncc12 +c1cc(-c2c[nH]c3ccncc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c[nH]c3ccncc23)c2ocnc2c1 +c1cc(-c2c[nH]c3ccncc23)c2[nH]c3ccncc3c2c1 +c1cc(-c2c[nH]c3nc4occc4nc23)c2c(c1)[nH]c1cnccc12 +c1cc(-c2c[nH]c3nc4occc4nc23)n[nH]1 +c1cc(-c2c[nH]c3nc4occc4nc23)[nH]n1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2nc3cc4ncoc4nc3o2)c2cc[nH]c2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2ncsc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2occc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2[nH]c3cnccc3c2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)c2[nH]ccc2c1 +c1cc(-c2nc3cc4ncoc4nc3o2)n[nH]1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)c2occc2c1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)c2sccc2c1 +c1cc(-c2nc3cc4nc[nH]c4cc3[nH]2)cnn1 +c1cc(-c2nc3cc4ocnc4cc3o2)c2c(c1)cnc1ccccc12 +c1cc(-c2nc3cc4ocnc4cc3o2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2nc3cc4ocnc4cc3o2)c2ccsc2c1 +c1cc(-c2nc3cc4ocnc4cc3o2)c2[nH]nnc2c1 +c1cc(-c2nc3cc4scnc4cc3s2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2nc3cc4scnc4cc3s2)c2ccsc2c1 +c1cc(-c2nc3cc4scnc4cc3s2)c2nccnc2c1 +c1cc(-c2nc3ccccc3c3ccccc23)c2ocnc2c1 +c1cc(-c2nc3ccccc3o2)c2occc2c1 +c1cc(-c2nc3nc4nc[nH]c4cc3[nH]2)c2c(c1)oc1ncccc12 +c1cc(-c2nc3nc4nc[nH]c4cc3[nH]2)c2cc[nH]c2c1 +c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2c(c1)sc1ncccc12 +c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2[nH]c3cnccc3c2c1 +c1cc(-c2nc3nc4ocnc4nc3o2)c2c(c1)sc1ncccc12 +c1cc(-c2nc3nc4ocnc4nc3o2)c2scnc2c1 +c1cc(-c2nccc3c2[nH]c2ccccc23)c2cc[nH]c2c1 +c1cc(-c2nccc3[nH]c4ccccc4c23)c2[nH]nnc2c1 +c1cc(-c2nccc3[nH]c4ccncc4c23)c2[nH]c3ccncc3c2c1 +c1cc(-c2nccc3[nH]ccc23)c2c(c1)cnc1ccccc12 +c1cc(-c2nccc3[nH]ccc23)c2c(c1)sc1ncccc12 +c1cc(-c2nccc3[nH]ccc23)c2nn[nH]c2c1 +c1cc(-c2nccs2)c2c(c1)[nH]c1ccncc12 +c1cc(-c2nccs2)c2ncsc2c1 +c1cc(-c2nccs2)c2[nH]nnc2c1 +c1cc(-c2ncno2)c2ccoc2c1 +c1cc(-c2ncon2)c2c(c1)[nH]c1cnccc12 +c1cc(-c2ncon2)c2sccc2c1 +c1cc(-c2ncon2)c2[nH]c3ccncc3c2c1 +c1cc(-c2ncon2)c2[nH]c3cnccc3c2c1 +c1cc(-c2ncon2)c2[nH]nnc2c1 +c1cc(-c2ncon2)[nH]n1 +c1cc(-n2c3ccccc3c3c4ccccc4[nH]c32)c2[nH]nnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2nccnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2ocnc2c1 +c1cc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c2sccc2c1 +c1cc(-n2c3ccccc3c3cccnc32)c2c(c1)cnc1ccccc12 +c1cc(-n2c3ccccc3c3cccnc32)c2ncsc2c1 +c1cc(-n2c3ccccc3c3cccnc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2occc2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2c3ccccc3c3ccncc32)c2[nH]nnc2c1 +c1cc(-n2c3ccccc3c3cnccc32)c2ocnc2c1 +c1cc(-n2c3ccncc3c3cnccc32)c2nn[nH]c2c1 +c1cc(-n2c3ccncc3c3cnccc32)c2ocnc2c1 +c1cc(-n2ccc3cc4ccoc4cc32)c2c(c1)cnc1ccccc12 +c1cc(-n2ccc3cc4ccoc4cc32)c2[nH]c3cnccc3c2c1 +c1cc(-n2ccc3cnccc32)c2c(c1)oc1ncccc12 +c1cc(-n2ccc3cnccc32)c2c(c1)[nH]c1ccncc12 +c1cc(-n2ccc3nc4ccoc4nc32)c2ncoc2c1 +c1cc(-n2cccn2)c2ncoc2c1 +c1cc(-n2cccn2)c2[nH]c3cnccc3c2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)c2ncsc2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)c2[nH]c3ccncc3c2c1 +c1cc(-n2cnc3cc4nc[nH]c4cc32)[nH]n1 +c1cc(-n2cnc3nc4nc[nH]c4nc32)c2ncoc2c1 +c1cc(-n2cnc3nc4nc[nH]c4nc32)c2[nH]ccc2c1 +c1cc2c(-c3c4ncoc4nc4ocnc34)c3ccoc3cc2[nH]1 +c1cc2c(-c3ccc4ncoc4c3)c3ccoc3cc2[nH]1 +c1cc2c(-c3ccc4[nH]nnc4c3)c3ccoc3cc2[nH]1 +c1cc2c(-n3cnc4nc5nc[nH]c5nc43)c3ccoc3cc2[nH]1 +c1cc2c(ccn2-c2cc3nc4ccoc4nc3[nH]2)cn1 +c1cc2c(ccn2-c2ccc3c(c2)[nH]c2ccncc23)cn1 +c1cc2c(ccn2-c2c[nH]c3nc4occc4nc23)cn1 +c1cc2c(ccn2-c2nc3cc4ocnc4cc3o2)cn1 +c1cc2c(ccn2-n2c3ccncc3c3cnccc32)cn1 +c1cc2c(ccn2-n2ccc3nc4ccoc4nc32)cn1 +c1cc2c(cn1)c1cnccc1n2-c1c2ccoc2cc2ccoc12 +c1cc2c(cn1)c1cnccc1n2-c1c2ncoc2cc2ncoc12 +c1cc2c(cn1)c1cnccc1n2-c1c2ncoc2nc2ocnc12 +c1cc2c(cn1)c1cnccc1n2-c1c2[nH]cnc2cc2nc[nH]c12 +c1cc2c(cn1)c1cnccc1n2-c1cc2cc3occc3cc2o1 +c1cc2c(cn1)c1cnccc1n2-c1cc2[nH]ccc2cn1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2c3c1CCCN3CCC2 +c1cc2c(cn1)c1cnccc1n2-c1ccc2cc[nH]c2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2ncoc2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2ocnc2c1 +c1cc2c(cn1)c1cnccc1n2-c1ccc2scnc2c1 +c1cc2c(cn1)c1cnccc1n2-c1c[nH]c2cc3occc3cc12 +c1cc2c(cn1)c1cnccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1cc2c(cn1)[nH]c1cc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4ncoc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4nn[nH]c4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4ocnc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4scnc4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1cc2c(cn1)[nH]c1cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1cc2c(cn1)[nH]c1cc(-n3cnc4cc5nc[nH]c5cc43)ccc12 +c1cc2c(cn1)[nH]c1cc(-n3cnc4nc5nc[nH]c5cc43)ccc12 +c1cc2c(cn1)[nH]c1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3ccc4cc[nH]c4c3)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3ccc4[nH]ccc4c3)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3cncc4c3[nH]c3ccncc34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3coc4cc5[nH]ccc5cc34)cc12 +c1cc2c(cn1)[nH]c1ccc(-c3nc4cc5ocnc5cc4o3)cc12 +c1cc2cc(-c3ccc4nn[nH]c4c3)ccc2s1 +c1cc2cc(-c3ccc4ocnc4c3)ccc2o1 +c1cc2cc(-n3ccc4nc5ccoc5nc43)ccc2o1 +c1cc2cc3c(-c4c5ncoc5nc5ocnc45)coc3cc2[nH]1 +c1cc2cc3c(-c4ccc5ccsc5c4)c[nH]c3cc2o1 +c1cc2cc3c(-c4ccc5nn[nH]c5c4)c[nH]c3cc2o1 +c1cc2cc3c(-c4ccon4)coc3cc2[nH]1 +c1cc2cc3c(-c4cnoc4)c[nH]c3cc2o1 +c1cc2cc3c(-c4nc5nc6nc[nH]c6nc5[nH]4)coc3cc2[nH]1 +c1cc2cc3c(-c4ncon4)coc3cc2[nH]1 +c1cc2cc3c(-n4cnc5cc6nc[nH]c6cc54)coc3cc2[nH]1 +c1cc2cc3c(-n4cnc5nc6nc[nH]c6cc54)coc3cc2[nH]1 +c1cc2cc3cc(-c4cc5cc6occc6cc5o4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5ccsc5c4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5sccc5c4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ccc5[nH]nnc5c4)[nH]c3cc2o1 +c1cc2cc3cc(-c4coc5cc6ccoc6cc45)[nH]c3cc2o1 +c1cc2cc3cc(-c4nc5cc6ncoc6nc5o4)oc3cc2[nH]1 +c1cc2cc3cc(-c4ncon4)oc3cc2[nH]1 +c1cc2cc3cc(-n4ccc5nc6ccoc6nc54)oc3cc2[nH]1 +c1cc2cc3ccn(-c4ccc5ccsc5c4)c3cc2o1 +c1cc2cc3ccn(-c4ccc5nn[nH]c5c4)c3cc2o1 +c1cc2cc3ccoc3c(-c3c4ncoc4nc4ocnc34)c2[nH]1 +c1cc2cc3ccoc3c(-c3cc4cc5occc5cc4o3)c2[nH]1 +c1cc2cc3ccoc3c(-c3ccc4ccsc4c3)c2[nH]1 +c1cc2cc3occ(-c4cn[nH]c4)c3cc2o1 +c1cc2cc3occ(-n4ccc5nc6ccoc6nc54)c3cc2o1 +c1cc2ccc(-c3ccc4[nH]nnc4c3)cc2[nH]1 +c1cc2ccc(-c3cncs3)cc2[nH]1 +c1cc2ccc(-c3cn[nH]c3)cc2s1 +c1cc2ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc2[nH]1 +c1cc2ccc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc2[nH]1 +c1cc2cnc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)cc2[nH]1 +c1cc2cnc(-c3ccc4scnc4c3)cc2[nH]1 +c1cc2cnc(-c3coc4cc5[nH]ccc5cc34)cc2[nH]1 +c1cc2cnc(-c3c[nH]c4cc5occc5cc34)cc2[nH]1 +c1cc2cnc(-n3ccc4nc5ccoc5nc43)cc2[nH]1 +c1cc2cncc(-c3c4[nH]ccc4cc4ccoc34)c2[nH]1 +c1cc2cncc(-c3ccc4ccsc4c3)c2[nH]1 +c1cc2cncc(-c3ccc4ncoc4c3)c2[nH]1 +c1cc2cncc(-c3ccc4[nH]nnc4c3)c2[nH]1 +c1cc2nc3c(-c4c5ncoc5nc5ocnc45)coc3nc2[nH]1 +c1cc2nc3c(-c4c5ncsc5cc5ncsc45)c[nH]c3nc2o1 +c1cc2nc3c(-c4ccc5nn[nH]c5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4ccc5sccc5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4ccc5[nH]nnc5c4)coc3nc2[nH]1 +c1cc2nc3c(-c4coc5cc6ccoc6cc45)coc3nc2[nH]1 +c1cc2nc3c(-c4nc5nc6ocnc6nc5o4)c[nH]c3nc2o1 +c1cc2nc3cc(-c4c5ncoc5nc5ocnc45)oc3nc2[nH]1 +c1cc2nc3cc(-c4c5ncoc5nc5ocnc45)[nH]c3nc2o1 +c1cc2nc3cc(-c4ccc5ocnc5c4)oc3nc2[nH]1 +c1cc2nc3cc(-c4ccon4)oc3nc2[nH]1 +c1cc2nc3cc(-c4cn[nH]c4)oc3nc2[nH]1 +c1cc2nc3ccn(-c4c5ncsc5cc5ncsc45)c3nc2o1 +c1cc2nc3ccn(-c4ccc5sccc5c4)c3nc2o1 +c1cc2nc3ccn(-c4ccc5scnc5c4)c3nc2o1 +c1cc2nc3ccn(-c4ccc5[nH]nnc5c4)c3nc2o1 +c1cc2nc3ccn(-c4cscn4)c3nc2o1 +c1cc2[nH]c(-c3ccc4sccc4c3)cc2cn1 +c1cc2[nH]c(-c3coc4cc5ccoc5cc34)cc2cn1 +c1cc2[nH]c3c(-c4c5ccoc5cc5ccoc45)cncc3c2cn1 +c1cc2[nH]c3c(-c4c5ncsc5cc5ncsc45)cncc3c2cn1 +c1cc2[nH]c3c(-c4c5[nH]cnc5cc5nc[nH]c45)cncc3c2cn1 +c1cc2[nH]c3c(-c4cc5cc6ccoc6cc5[nH]4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccc5sccc5c4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccc5scnc5c4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccno4)cncc3c2cn1 +c1cc2[nH]c3c(-c4ccon4)cncc3c2cn1 +c1cc2[nH]c3c(-c4cnoc4)cncc3c2cn1 +c1cc2[nH]c3c(-c4c[nH]c5nc6occc6nc45)cncc3c2cn1 +c1cc2[nH]c3cc(-c4c5cc[nH]c5cc5occc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cc5c6c(c4)CCCN6CCC5)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cc5cc6ccoc6cc5[nH]4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5ccoc5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5[nH]c6ccncc6c5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4ccc5[nH]nnc5c4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4cncc5c4[nH]c4ccncc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4coc5nc6[nH]ccc6nc45)ncc3c2cn1 +c1cc2[nH]c3cc(-c4nc5cc6nc[nH]c6cc5[nH]4)ncc3c2cn1 +c1cc2[nH]c3cc(-c4nc5nc6nc[nH]c6cc5[nH]4)ccc3c2cn1 +c1cc2[nH]c3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c2cn1 +c1cc2[nH]c3ccc(-c4cc5nc6cc[nH]c6nc5o4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4cc5[nH]ccc5cn4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4nc5nc6nc[nH]c6nc5[nH]4)cc3c2cn1 +c1cc2[nH]c3ccc(-c4ncon4)cc3c2cn1 +c1cc2[nH]c3ccnc(-c4c5ccoc5cc5ccoc45)c3c2cn1 +c1cc2[nH]c3ccnc(-c4cc5c6c(c4)CCCN6CCC5)c3c2cn1 +c1cc2[nH]c3ccnc(-c4ccc5nn[nH]c5c4)c3c2cn1 +c1cc2[nH]c3ccnc(-c4cnoc4)c3c2cn1 +c1cc2[nH]c3ccnc(-c4ncno4)c3c2cn1 +c1cc2[nH]cc(-c3ccc4[nH]nnc4c3)c2cn1 +c1cc2[nH]cc(-c3ccn[nH]3)c2cn1 +c1cc2[nH]cc(-c3cncc4c3[nH]c3ccncc34)c2cn1 +c1cc2[nH]cc(-c3coc4cc5[nH]ccc5cc34)c2cn1 +c1cc2[nH]cc(-c3coc4nc5[nH]ccc5nc34)c2cn1 +c1cc2[nH]cc(-c3nc4cc5ocnc5cc4o3)c2cn1 +c1cc2[nH]cc(-n3cnc4nc5nc[nH]c5nc43)c2cn1 +c1cc2[nH]ccc2c(-c2cc3cc4ccoc4cc3[nH]2)n1 +c1cc2[nH]ccc2c(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cc2)n1 +c1cc2[nH]ccc2c(-c2ccc3ccoc3c2)n1 +c1ccc(-c2c3[nH]ccc3cc3ccoc23)c(-c2cnccn2)c1 +c1ccc(-c2c3[nH]cnc3cc3nc[nH]c23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1(c2nccc(c2)c2ccc3CCc4c(cccc4)Nc3c2)ncccc1 +c1ccc(-c2cc(-c3ccc4c(n3)sc3ncccc34)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4c5c3CCCN5CCC4)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4oc5ccccc5c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c3sc3ncccc34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c3[nH]c3cnccc34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4c5ccccc5c5nccnc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3cccc4cnc5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3cncc4[nH]c5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc(-c3coc4cc5ccoc5cc34)ccn2)nc1 +c1ccc(-c2cc(-c3coc4nc5[nH]ccc5nc34)ccn2)nc1 +c1ccc(-c2cc(-c3nccc4[nH]c5ccccc5c34)ccn2)nc1 +c1ccc(-c2cc3c4c(c2-c2cc5cccnc5c5ncccc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cc5cnccc5[nH]2)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5c2[nH]c2ncccc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5cnc6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5ocnc25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cccc5sc6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4c(c2-c2cncc5[nH]c6ccccc6c25)CCCN4CCC3)cc1 +c1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)c(-c2cnccn2)c1 +c1ccc(-c2cc3nc4cc[nH]c4nc3o2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cc3nc4cc[nH]c4nc3o2)c(-c2cnccn2)c1 +c1(c2ncc(cc2)N2c3c(Sc4c2cccc4)cccc3)ncccc1 +c1ccc(-c2ccc(-c3c4cc[nH]c4cc4occc34)cn2)nc1 +c1ccc(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cn2)nc1 +c1(c2ncc(cc2)c2cc3c(Sc4c(cccc4)N3)cc2)ncccc1 +c1ccc(-c2ccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)cn2)nc1 +c1ccc(-c2ccc(-c3ccc4c(c3)Oc3ccccc3O4)cn2)nc1 +c1ccc(-c2ccc(-c3ccc4c(c3)[nH]c3ccncc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c3cnc3ccccc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c3[nH]c3cnccc34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cn2)nc1 +c1ccc(-c2ccc(-c3cccc4cc[nH]c34)cn2)nc1 +c1ccc(-c2ccc(-c3ccnnc3)cn2)nc1 +c1ccc(-c2ccc(-c3cnc4oc5ccccc5c4c3)cn2)nc1 +c1ccc(-c2ccc(-c3cnc4sc5ncccc5c4c3)cn2)nc1 +c1ccc(-c2ccc(-n3c4ccccc4c4c5ccccc5[nH]c43)cn2)nc1 +c1ccc(-c2ccc(-n3c4ccccc4c4cnccc43)cn2)nc1 +c1ccc(-c2ccc3c(c2)[nH]c2cnccc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccc3ccc4cccnc4c3n2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccc3nn[nH]c3c2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc(-c3c4ccoc4cc4ccoc34)n2)nc1 +c1ccc(-c2cccc(-c3c4cc[nH]c4cc4occc34)n2)nc1 +c1ccc(-c2cccc(-c3cc4cc5occc5cc4o3)n2)nc1 +c1ccc(-c2cccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)n2)nc1 +c1(c2ncccc2)nc(ccc1)c1cc2CCc3c(cccc3)Nc2cc1 +c1ccc(-c2cccc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)n2)nc1 +c1ccc(-c2cccc(-c3ccc4cc[nH]c4c3)n2)nc1 +c1ccc(-c2cccc(-c3ccc4ncoc4c3)n2)nc1 +c1ccc(-c2cccc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)n2)nc1 +c1ccc(-c2cccc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)nc1 +c1(c2ncccc2)nc(ccc1)c1c2CCc3c(cccc3)Nc2ccc1 +c1ccc(-c2cccc(-c3cccc4c3oc3ccccc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4oc5ccccc5c34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4ocnc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4sccc34)n2)nc1 +c1ccc(-c2cccc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)n2)nc1 +c1ccc(-c2cccc(-c3cccnn3)n2)nc1 +c1ccc(-c2cccc(-c3cnc4oc5ccccc5c4c3)n2)nc1 +c1ccc(-c2cccc(-c3cnc4sc5ccccc5c4c3)n2)nc1 +c1ccc(-c2cccc(-c3coc4cc5ccoc5cc34)n2)nc1 +c1ccc(-c2cccc(-c3coc4nc5[nH]ccc5nc34)n2)nc1 +c1ccc(-c2cccc(-n3c4ccccc4c4c5ccccc5[nH]c43)n2)nc1 +c1ccc(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c2[nH]c2ccncc23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c2[nH]c2ncccc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc3c4ccccc4c4nccnc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3cc[nH]c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3ocnc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cccc3sc4ncccc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]c4ccncc4c23)c(-c2cnccn2)c1 +c1ccc(-c2cccc3[nH]nnc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2ccn[nH]2)c(-c2cnccn2)c1 +c1ccc(-c2cnc(-c3c4ccoc4cc4ccoc34)cn2)cc1 +c1ccc(-c2cnc(-c3c4ncoc4cc4ncoc34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)Oc3ccccc3O4)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4c(c3)[nH]c3ccncc34)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4cnc5ccccc5c4c3)cn2)cc1 +c1ccc(-c2cnc(-c3ccc4ncsc4c3)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c3cnc3ccccc34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4ncsc34)cn2)cc1 +c1ccc(-c2cnc(-c3cccc4oc5ncccc5c34)cn2)cc1 +c1ccc(-c2cnc(-c3cccnn3)cn2)cc1 +c1ccc(-c2cnc(-c3coc4ccccc34)cn2)cc1 +c1ccc(-c2cnc(-c3c[nH]c4nc5occc5nc34)cn2)cc1 +c1ccc(-c2cnc(-n3ccc4ccccc43)cn2)cc1 +c1ccc(-c2cnc3[nH]c4ccccc4c3c2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cncc(-c3cc4cc5ccoc5cc4[nH]3)n2)cc1 +c1ccc(-c2cncc(-c3cc4cc5occc5cc4o3)n2)cc1 +c1ccc(-c2cncc(-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +c1ccc(-c2cncc(-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)ncc3ccccc34)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)oc3ccccc34)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +c1ccc(-c2cncc(-c3ccc4c(cnc5ccccc54)c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4ccsc4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4ncc5ccccc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4sccc4c3)n2)cc1 +c1ccc(-c2cncc(-c3ccc4[nH]c5ccncc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +c1(c2nc(cnc2)c2c3c(CCc4c(cccc4)N3)ccc2)ccccc1 +c1ccc(-c2cncc(-c3cccc4c3[nH]c3ccncc34)n2)cc1 +c1ccc(-c2cncc(-c3cccc4c5ccccc5c5nccnc5c34)n2)cc1 +c1ccc(-c2cncc(-c3cccc4cnc5ccccc5c34)n2)cc1 +c1ccc(-c2cncc(-c3cnc4sc5ncccc5c4c3)n2)cc1 +c1ccc(-c2cncc(-c3cncc4c3[nH]c3ccccc34)n2)cc1 +c1ccc(-c2cncc(-n3c4ccccc4c4c5ccccc5[nH]c43)n2)cc1 +c1ccc(-c2cnccn2)c(-c2ccc3c(c2)c2ccccc2c2nccnc32)c1 +c1ccc(-c2cnccn2)c(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +c1ccc(-c2cnccn2)c(-c2ccc3ccoc3c2)c1 +c1ccc(-c2cnccn2)c(-c2ccc3sccc3c2)c1 +c1ccc(-c2cncs2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2coc3cc4ccoc4cc23)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2cscn2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-c2c[nH]c3ccccc23)c(-c2cnccn2)c1 +c1ccc(-c2c[nH]c3nc4occc4nc23)c(-c2cnccn2)c1 +c1ccc(-c2nc3ccccc3s2)c(-c2cnccn2)c1 +c1ccc(-c2nccc3[nH]c4ccncc4c23)c(-c2cnccn2)c1 +c1(c2ncccc2N2c3c(CCc4c2cccc4)cccc3)ncccc1 +c1ccc(-c2ncccc2-c2c3ccoc3cc3ccoc23)nc1 +c1ccc(-c2ncccc2-c2cc3ccccc3[nH]2)nc1 +c1ccc(-c2ncccc2-c2cc3nc4ccoc4nc3[nH]2)nc1 +c1ccc(-c2ncccc2-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)nc1 +c1ccc(-c2ncccc2-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)nc1 +c1ccc(-c2ncccc2-c2ccc3c(c2)oc2ccccc23)nc1 +c1ccc(-c2ncccc2-c2ccc3c(cnc4ccccc43)c2)nc1 +c1ccc(-c2ncccc2-c2ccc3ncsc3c2)nc1 +c1ccc(-c2ncccc2-c2ccc3ocnc3c2)nc1 +c1ccc(-c2ncccc2-c2ccc3sccc3c2)nc1 +c1ccc(-c2ncccc2-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)nc1 +c1ccc(-c2ncccc2-c2cccc3c4ccccc4c4nc[nH]c4c23)nc1 +c1ccc(-c2ncccc2-c2cccc3c4ccccc4c4[nH]cnc4c23)nc1 +c1ccc(-c2ncccc2-c2cccc3c4[nH]cnc4c4ccccc4c23)nc1 +c1ccc(-c2ncccc2-c2coc3cc4[nH]ccc4cc23)nc1 +c1ccc(-c2ncccc2-c2c[nH]c3ccccc23)nc1 +c1ccc(-c2ncccc2-c2nc3ccccc3c3ccccc23)nc1 +c1ccc(-c2ncccc2-n2c3ccncc3c3cnccc32)nc1 +c1ccc(-c2ncccc2-n2ccc3cc4ccoc4cc32)nc1 +c1ccc(-c2nccnc2-c2cc3cc4occc4cc3o2)cc1 +c1ccc(-c2nccnc2-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1 +c1ccc(-c2nccnc2-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)cc1 +c1ccc(-c2nccnc2-c2ccc3c4ccccc4c4nccnc4c3c2)cc1 +c1ccc(-c2nccnc2-c2ccc3[nH]c4ccncc4c3c2)cc1 +c1ccc(-c2nccnc2-c2ccc3[nH]ccc3c2)cc1 +c1ccc(-c2nccnc2-c2cccc3c2sc2ncccc23)cc1 +c1ccc(-c2nccnc2-c2cccc3c4nc[nH]c4c4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2cccc3nn[nH]c23)cc1 +c1ccc(-c2nccnc2-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)cc1 +c1ccc(-c2nccnc2-c2cccc3[nH]c4cnccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccccc2N(c2ccccc2)c2ccccc2)cc1 +c1ccc(-c2nccnc2-c2ccnc3oc4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccnc3sc4ccccc4c23)cc1 +c1ccc(-c2nccnc2-c2ccnc3sc4ncccc4c23)cc1 +c1ccc(-c2nccnc2-c2cncc3c2[nH]c2ccncc23)cc1 +c1ccc(-c2nccnc2-c2cn[nH]c2)cc1 +c1ccc(-c2nccnc2-c2nc3ccccc3c3ccccc23)cc1 +c1ccc(-c2nccnc2-n2c3ccccc3c3cnccc32)cc1 +c1ccc(-c2nccnc2-n2c3ccncc3c3cnccc32)cc1 +c1ccc(-c2nccnc2-n2cnc3nc4nc[nH]c4nc32)cc1 +c1ccc(-c2ncno2)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c(-c2cnccn2)c1 +c1ccc(-n2c3ccccc3c3cccnc32)c(-c2cc3c4c(c2)CCCN4CCC3)c1 +c1ccc(-n2c3ccccc3c3cnccc32)c(-c2cnccn2)c1 +c1ccc(N(c2ccccc2)c2ccc(-c3cc4nc5cc[nH]c5nc4o3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cc4[nH]c5ccncc5c4cn3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4cnc5ccccc5c4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4nn[nH]c4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3ccc4[nH]nnc4c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc(-c4cnccn4)c3)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4c3cnc3ccccc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cccc4ocnc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3cncc4c3[nH]c3ccncc34)cc2)cc1 +c1ccc(N(c2ccccc2)c2ccc(-c3nccc4[nH]c5ccncc5c34)cc2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c(c3)ncc3ccccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c(c3)sc3ccccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc(-c4cnccn4)c3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4c3[nH]c3ncccc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4cnc5ccccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4ncoc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4[nH]c5ncccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cccc4[nH]nnc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cnc4[nH]c5ccccc5c4c3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cncc4[nH]c5ccccc5c34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3cnoc3)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-c3c[nH]c4ccncc34)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3ccc4cnccc43)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3cnc4nc5nc[nH]c5nc43)c2)cc1 +c1ccc(N(c2ccccc2)c2cccc(-n3nnc4ccccc43)c2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2c3ncoc3nc3ocnc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cc3[nH]c4ccncc4c3cn2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccc3c(c2)[nH]c2cnccc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccc3ccc4cccnc4c3n2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cccc3c2B2c4ccccc4Oc4cccc(c42)O3)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2cccc3[nH]c4ncccc4c23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ccno2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2coc3cc4ccoc4cc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2coc3nc4[nH]ccc4nc23)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2nc3nc4nc[nH]c4nc3[nH]2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2nccs2)cc1 +c1ccc(N(c2ccccc2)c2ccccc2-c2ncno2)cc1 +c1ccc2c(-c3c4ccoc4cc4ccoc34)coc2c1 +c1ccc2c(-c3c4cc[nH]c4cc4occc34)csc2c1 +c1ccc2c(-c3c4ncoc4nc4ocnc34)csc2c1 +c1ccc2c(-c3c4nc[nH]c4cc4[nH]cnc34)csc2c1 +c1ccc2c(-c3c4[nH]cnc4cc4nc[nH]c34)coc2c1 +c1ccc2c(-c3c4[nH]cnc4nc4nc[nH]c34)csc2c1 +c1ccc2c(-c3cc4cnccc4[nH]3)coc2c1 +c1ccc2c(-c3cc4nc5ccoc5nc4[nH]3)coc2c1 +c1ccc2c(-c3cc4nc5cc[nH]c5nc4o3)coc2c1 +c1ccc2c(-c3cc4nc5cc[nH]c5nc4o3)c[nH]c2c1 +c1ccc2c(-c3ccc(-c4cnccn4)cc3)c[nH]c2c1 +c1ccc2c(-c3ccc4c(c3)c3ccccc3c3nccnc43)csc2c1 +c1ccc2c(-c3ccc4c(c3)sc3ncccc34)csc2c1 +c1ccc2c(-c3ccc4ccsc4c3)csc2c1 +c1ccc2c(-c3ccc4ocnc4c3)c[nH]c2c1 +c1ccc2c(-c3ccc4[nH]c5ncccc5c4c3)c[nH]c2c1 +c1ccc2c(-c3ccc4[nH]nnc4c3)coc2c1 +c1ccc2c(-c3cccc4c3[nH]c3cnccc34)csc2c1 +c1ccc2c(-c3cccc4c3[nH]c3ncccc34)coc2c1 +c1ccc2c(-c3cccc4c3[nH]c3ncccc34)csc2c1 +c1ccc2c(-c3cccc4c5nccnc5c5ccccc5c34)csc2c1 +c1ccc2c(-c3cccc4ocnc34)c[nH]c2c1 +c1ccc2c(-c3cccc4sc5ccccc5c34)coc2c1 +c1ccc2c(-c3ccnc4ncccc34)c[nH]c2c1 +c1ccc2c(-c3ccnnc3)csc2c1 +c1ccc2c(-c3cnc4nccnc4n3)coc2c1 +c1ccc2c(-c3cncs3)c[nH]c2c1 +c1ccc2c(-c3coc4cc5ccoc5cc34)c[nH]c2c1 +c1ccc2c(-c3csc4ccccc34)c[nH]c2c1 +c1ccc2c(-c3cscn3)csc2c1 +c1ccc2c(-c3c[nH]c4nc5occc5nc34)coc2c1 +c1ccc2c(-c3nc4cc5ncoc5nc4o3)c[nH]c2c1 +c1ccc2c(-c3nccc4[nH]ccc34)coc2c1 +c1ccc2c(-n3c4ccccc4c4cccnc43)coc2c1 +c1ccc2c(-n3c4ccccc4c4cccnc43)c[nH]c2c1 +c1ccc2c(-n3c4ccccc4c4cnccc43)csc2c1 +c1ccc2c(-n3ccc4nc5ccoc5nc43)c[nH]c2c1 +c1ccc2c(-n3cnc4nc5nc[nH]c5nc43)coc2c1 +c1ccc2c(-n3cnc4nc5nc[nH]c5nc43)c[nH]c2c1 +c12c(ccnc2)[nH]c(c1)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(c3c(cc(nc3)c3c4c(Sc5c(cccc5)N4)ccc3)[nH]2)cncc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +c12c(cccc2)cnc2c1ccc(c2)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(scc1)cc(cc2)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(c(ccc2)c2c3c(Sc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c1(c2nccnc2)ccccc1c1c2c(Sc3c(cccc3)N2)ccc1 +n1oc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +n1c(csc1)c1c2c(Sc3c(cccc3)N2)ccc1 +c12c(ccnc2c2c3c(Sc4c(cccc4)N3)ccc2)[nH]cc1 +c12c(scc1)ccc(c2)c1cc2c(Sc3c(cccc3)N2)cc1 +n1c2c(ncc(c2)c2cc3c(Sc4c(cccc4)N3)cc2)ccc1 +c12c(c3c(c(cnc3)c3cc4c(Sc5c(cccc5)N4)cc3)[nH]2)cncc1 +n1c2c(cc3c(nc(c4cc5c(Sc6c(cccc6)N5)cc4)[nH]3)c2)[nH]c1 +n1c2nc3oc(nc3nc2oc1)c1cc2c(Sc3c(cccc3)N2)cc1 +n1ccsc1c1cc2c(Sc3c(cccc3)N2)cc1 +c12c(c3c(n1c1cc4c(Sc5c(cccc5)N4)cc1)ccnc3)cncc2 +c12nc3c(occ3)nc1[nH]c(c2)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(cc(nc2)c2ccc3c(Sc4c(cccc4)N3)c2)[nH]cc1 +c12c(ccc(c2)c2ccc3c(Sc4c(cccc4)N3)c2)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(c(ccc2)c2ccc3c(Sc4c(cccc4)N3)c2)[nH]c2c1ccnc2 +c12c(cccc2c2ccc3c(Sc4c(cccc4)N3)c2)cnc2c1cccc2 +n1oc(cc1)c1ccc2c(Sc3c(cccc3)N2)c1 +c12c(ccnc2)[nH]cc1c1ccc2c(Sc3c(cccc3)N2)c1 +n1c2c(n(c1)c1ccc3c(Sc4c(cccc4)N3)c1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +c1(c2nccnc2)ccc(cc1)c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(cc(cc2)c2c3c(ccc2)Nc2c(S3)cccc2)[nH]c2ncccc12 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +n1c2c(oc1)cccc2c1c2c(ccc1)Nc1c(S2)cccc1 +n1occc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(c3c(c(cnc3)c3c4c(ccc3)Nc3c(S4)cccc3)[nH]2)cncc1 +c12c(ccnc2)[nH]cc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(ccc1)Nc1c(S2)cccc1 +n1cnoc1c1c2c(ccc1)Nc1c(S2)cccc1 +c12c(n(c3c1ccnc3)c1c3c(ccc1)Nc1c(S3)cccc1)cccc2 +n1c2c(nc3c(nco3)c2N2c3c(Sc4c2cccc4)cccc3)oc1 +c12c(cc(nc2)N2c3c(Sc4c2cccc4)cccc3)[nH]cc1 +c12c(cc(cc2)N2c3c(Sc4c2cccc4)cccc3)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)N1c2c(Sc3c1cccc3)cccc2 +n1c2c(nc(cc2)N2c3c(Sc4c2cccc4)cccc3)ccc1 +c12c(sc3c1cccc3N1c3c(Sc4c1cccc4)cccc3)cccc2 +n1c2c(oc1)c(ccc2)N1c2c(Sc3c1cccc3)cccc2 +c12c(nn[nH]2)cccc1N1c2c(Sc3c1cccc3)cccc2 +c12c(cccc2N2c3c(Sc4c2cccc4)cccc3)[nH]c2ncccc12 +c12c(nn[nH]2)c(ccc1)N1c2c(Sc3c1cccc3)cccc2 +c1(c2nccnc2)ccccc1N1c2c(Sc3c1cccc3)cccc2 +c12c(cccc2)[nH]c2ncc(cc12)N1c2c(Sc3c1cccc3)cccc2 +c12nc3c(occ3N3c4c(Sc5c3cccc5)cccc4)nc1[nH]cc2 +c12c(ccnc2N2c3c(Sc4c2cccc4)cccc3)[nH]cc1 +c12nc3c(occ3)nc1n(cc2)N1c2c(Sc3c1cccc3)cccc2 +c1ccc2c(c1)c1cc(-c3c4ccoc4cc4ccoc34)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3c4ccoc4cc4ccoc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3c4ncoc4nc4ocnc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3cc4cnccc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3cc4nc5ccoc5nc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3cc4nc5cc[nH]c5nc4o3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3cc4[nH]ccc4cn3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4nn[nH]c4c3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3ccc4[nH]nnc4c3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ccon3)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-c3cnc4nccnc4n3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3cscn3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3nc4nc5ocnc5nc4o3)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3nccc4[nH]ccc34)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-c3ncon3)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4cccnc43)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1cc(-n3c4ccccc4c4ccncc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3ccc4nc5ccoc5nc43)ccc1c1nc[nH]c21 +c1ccc2c(c1)c1cc(-n3cnc4nc5nc[nH]c5cc43)ccc1c1nccnc21 +c1ccc2c(c1)c1cc(-n3cnc4nc5nc[nH]c5nc43)ccc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3c4ccoc4cc4ccoc34)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cc4cnccc4[nH]3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3ccc(-c4cnccn4)cc3)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3ccc4c(c3)[nH]c3cnccc34)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3ccc4sccc4c3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3ccc4[nH]nnc4c3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cncc4c3[nH]c3ccncc34)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3cncs3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3cnoc3)cc1c1nccnc21 +c1ccc2c(c1)c1ccc(-c3cnoc3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3coc4cc5ccoc5cc34)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nc4cc5ncoc5nc4o3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nc4nc5nc[nH]c5cc4[nH]3)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-c3nc4nc5ocnc5nc4o3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-c3nccs3)cc1c1[nH]cnc21 +c1ccc2c(c1)c1ccc(-n3c4ccncc4c4cnccc43)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-n3cnc4nc5nc[nH]c5nc43)cc1c1nc[nH]c21 +c1ccc2c(c1)c1ccc(-n3cnc4nc5nc[nH]c5nc43)cc1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c4ncoc4nc4ocnc34)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3c4ncoc4nc4ocnc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c4nc[nH]c4cc4[nH]cnc34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3ccc4ncoc4c3)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3ccc4[nH]nnc4c3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3cncs3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3cscn3)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3c[nH]c4ccncc34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3c[nH]c4nc5occc5nc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3nc4cc5ncoc5nc4o3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]c5ccncc5c34)c1c1nccnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]c5ccncc5c34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]ccc34)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-c3nccc4[nH]ccc34)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-c3ncon3)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-n3cnc4cc5nc[nH]c5cc43)c1c1nc[nH]c21 +c1ccc2c(c1)c1cccc(-n3cnc4nc5nc[nH]c5cc43)c1c1[nH]cnc21 +c1ccc2c(c1)c1cccc(-n3cnc4nc5nc[nH]c5nc43)c1c1[nH]cnc21 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1cc2nc3ccoc3nc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1c[nH]c2ccncc12 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nc2nc3nc[nH]c3nc2[nH]1 +c1ccc2c(c1)c1ccccc1c1c2ncn1-c1nccc2[nH]ccc12 +c1ccc2c(c1)c1ccccc1c1nc(-c3cc4cnccc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3cc4[nH]c5ccncc5c4cn3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3ccc(-c4cnccn4)cc3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3c[nH]c4nc5occc5nc34)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3nc4cc5nc[nH]c5cc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3nc4nc5nc[nH]c5cc4[nH]3)cnc21 +c1ccc2c(c1)c1ccccc1c1nc(-c3ncno3)cnc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cc4[nH]ccc4cn3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3ccc4ncoc4c3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3ccc4[nH]nnc4c3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cnc4nccnc4n3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3cncc4cc[nH]c34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3coc4nc5[nH]ccc5nc34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3c[nH]c4nc5occc5nc34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3nc4cc5nc[nH]c5cc4[nH]3)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-c3nccc4[nH]c5ccncc5c34)nc21 +c1ccc2c(c1)c1ccccc1c1[nH]c(-n3cnc4nc5nc[nH]c5cc43)nc21 +c1ccc2c(c1)c1cccnc1n2-c1cc2cc3occc3cc2o1 +c1ccc2c(c1)c1cccnc1n2-c1cc2nc3cc[nH]c3nc2o1 +c1ccc2c(c1)c1cccnc1n2-c1ccc2sccc2c1 +c1ccc2c(c1)c1cccnc1n2-c1ccn[nH]1 +c1ccc2c(c1)c1cccnc1n2-c1c[nH]c2cc3occc3cc12 +c1ccc2c(c1)c1cccnc1n2-c1c[nH]c2nc3occc3nc12 +c1ccc2c(c1)c1ccncc1n2-c1c2cc[nH]c2cc2occc12 +c1ccc2c(c1)c1ccncc1n2-c1cc2cc3cc[nH]c3cc2o1 +c1ccc2c(c1)c1ccncc1n2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)c1ccncc1n2-c1ccn[nH]1 +c1ccc2c(c1)c1ccncc1n2-c1cc[nH]n1 +c1ccc2c(c1)c1ccncc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)c1ccncc1n2-c1c[nH]c2ccncc12 +c1ccc2c(c1)c1ccncc1n2-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1ccncc1n2-n1c2ccccc2c2cccnc21 +c1ccc2c(c1)c1ccncc1n2-n1ccc2cc3ccoc3cc21 +c1ccc2c(c1)c1cnccc1n2-c1ccc2c(c1)[nH]c1cnccc12 +c1ccc2c(c1)c1cnccc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)c1cnccc1n2-c1nc2nc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)c1cnccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1ccc2c(c1)c1cnccc1n2-n1cnc2nc3nc[nH]c3nc21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3cc4[nH]ccc4cn3)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3ccc4nn[nH]c4c3)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-c3nccc4[nH]c5ccncc5c34)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-n3ccc4cnccc43)c21 +c1ccc2c(c1)c1nccnc1c1cccc(-n3cnc4nc5nc[nH]c5cc43)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3cncc4cc[nH]c34)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3cnoc3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3nc4nc5ocnc5nc4o3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-c3ncno3)c21 +c1ccc2c(c1)c1nc[nH]c1c1cccc(-n3c4ccncc4c4cnccc43)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3cc4[nH]ccc4cn3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3ccc4ocnc4c3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3ccc4[nH]c5cnccc5c4c3)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3cncc4c3[nH]c3ccncc34)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-c3coc4cc5ccoc5cc34)c21 +c1ccc2c(c1)c1[nH]cnc1c1cccc(-n3ccc4nc5ccoc5nc43)c21 +c12c(occ1)c(c1c(occ1)c2)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2c(nc3c(nco3)c2c2c3CCc4c(cccc4)Nc3ccc2)oc1 +c12c(cc(nc2)c2c3CCc4c(cccc4)Nc3ccc2)[nH]cc1 +c12c(cccc2)[nH]c2nc(ccc12)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2nc(ccc2ccc1)c1c2CCc3c(cccc3)Nc2ccc1 +c12c(ccc(c2)c2c3CCc4c(cccc4)Nc3ccc2)cnc2c1cccc2 +c12c(ccc(c2)c2c3CCc4c(cccc4)Nc3ccc2)[nH]c2c1ccnc2 +c12nccnc1c(ccc2)c1c2CCc3c(cccc3)Nc2ccc1 +n1cc(sc1)c1c2CCc3c(cccc3)Nc2ccc1 +c12nc3c(occ3c3c4CCc5c(cccc5)Nc4ccc3)nc1[nH]cc2 +n1ccsc1c1c2CCc3c(cccc3)Nc2ccc1 +c12c(n(c3ncccc13)c1c3CCc4c(cccc4)Nc3ccc1)cccc2 +c12c(n(c3c1ccnc3)c1c3CCc4c(cccc4)Nc3ccc1)cccc2 +n1c2c(n(c1)c1c3CCc4c(cccc4)Nc3ccc1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1c2CCc3c(cccc3)Nc2ccc1 +n1c2c(cc3c(nc[nH]3)c2c2cc3CCc4c(cccc4)Nc3cc2)[nH]c1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1cc3CCc5c(cccc5)Nc3cc1)cccc4)cccc2 +c1(c2nccnc2)ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(nc(cc2)c2cc3CCc4c(cccc4)Nc3cc2)ccc1 +c12c(ccc(c2)c2cc3CCc4c(cccc4)Nc3cc2)[nH]c2c1ccnc2 +c12c(ccc(c2)c2cc3CCc4c(cccc4)Nc3cc2)[nH]c2ncccc12 +c12c(cccc2)cnc2c1c(ccc2)c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(nccc2)c(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +c12c(cccc2)[nH]c2nccc(c12)c1cc2CCc3c(cccc3)Nc2cc1 +c12c(occ1)cc1c(occ1c1cc3CCc4c(cccc4)Nc3cc1)c2 +c12c(ccnc2)[nH]cc1c1cc2CCc3c(cccc3)Nc2cc1 +n1c2c(cc3c(nc(c4cc5CCc6c(cccc6)Nc5cc4)[nH]3)c2)[nH]c1 +c12c(ccnc2c2cc3CCc4c(cccc4)Nc3cc2)[nH]cc1 +n1ccsc1c1cc2CCc3c(cccc3)Nc2cc1 +c12c(nnn1c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +n1c2c(nc3c(nco3)c2c2ccc3CCc4c(cccc4)Nc3c2)oc1 +c12c(cc(cc2)c2ccc3CCc4c(cccc4)Nc3c2)cnc2c1cccc2 +c12c(cccc2)cnc2c1cccc2c1ccc2CCc3c(cccc3)Nc2c1 +c12c(sc3c1c(ccc3)c1ccc3CCc4c(cccc4)Nc3c1)cccc2 +c12c(cccc2c2ccc3CCc4c(cccc4)Nc3c2)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nccc1c1ccc2CCc3c(cccc3)Nc2c1 +n1occc1c1ccc2CCc3c(cccc3)Nc2c1 +n1occ(c1)c1ccc2CCc3c(cccc3)Nc2c1 +n1c(csc1)c1ccc2CCc3c(cccc3)Nc2c1 +c12nc3c(occ3)nc1[nH]cc2c1ccc2CCc3c(cccc3)Nc2c1 +n1c2c(cc3c(nc(c4ccc5CCc6c(cccc6)Nc5c4)[nH]3)c2)[nH]c1 +n1cnoc1c1ccc2CCc3c(cccc3)Nc2c1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c1 +c12nc3c(oc(c3)c3c4c(CCc5c(cccc5)N4)ccc3)nc1[nH]cc2 +c12c(cc(cc2)c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c12c(scc1)cc(cc2)c1c2c(CCc3c(cccc3)N2)ccc1 +n1c2c(oc1)ccc(c2)c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(ccc(c2)c2c3c(CCc4c(cccc4)N3)ccc2)[nH]c2ncccc12 +c12c(c(ccc2)c2c3c(CCc4c(cccc4)N3)ccc2)cnc2c1cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +c12c(c(ccc2)c2c3c(ccc2)CCc2c(cccc2)N3)[nH]c2c1ccnc2 +c12c(sc3c1c(ccc3)c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +c12c(scc1)cccc2c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(cccc2)c(nc2c1cccc2)c1c2c(CCc3c(cccc3)N2)ccc1 +n1c2nc3nc(c4c5c(CCc6c(cccc6)N5)ccc4)[nH]c3cc2[nH]c1 +c12c(cccc2)[nH]c2c1ccnc2c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(CCc3c(cccc3)N2)ccc1 +n1ccsc1c1c2c(CCc3c(cccc3)N2)ccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)N1c3c(CCc5c1cccc5)cccc3)cccc4)cccc2 +c12nc3c(oc(c3)N3c4c(CCc5c3cccc5)cccc4)nc1[nH]cc2 +n1c2c(nc(cc2)N2c3c(CCc4c2cccc4)cccc3)ccc1 +c12c(nn[nH]2)cc(cc1)N1c2c(CCc3c1cccc3)cccc2 +c12c(sc3c1cccc3N1c3c(CCc4c1cccc4)cccc3)cccc2 +c12c(c(ccc2)N2c3c(CCc4c2cccc4)cccc3)[nH]c2ncccc12 +c12c(cccc2N2c3c(CCc4c2cccc4)cccc3)[nH]c2ncccc12 +n1oc(cc1)N1c2c(CCc3c1cccc3)cccc2 +n1c2c(cc3c(nc([nH]3)N3c4c(CCc5c3cccc5)cccc4)c2)[nH]c1 +c12c(cccc2)[nH]c2c1ccnc2N1c2c(CCc3c1cccc3)cccc2 +c12c(c3c(ccnc3)[nH]2)c(ncc1)N1c2c(CCc3c1cccc3)cccc2 +c12c(n(c3c1ccnc3)N1c3c(CCc4c1cccc4)cccc3)cccc2 +c1ccc2c(c1)ccn2-c1c2nc[nH]c2cc2[nH]cnc12 +c1ccc2c(c1)ccn2-c1c2[nH]cnc2cc2nc[nH]c12 +c1ccc2c(c1)ccn2-c1c2[nH]cnc2nc2nc[nH]c12 +c1ccc2c(c1)ccn2-c1ccc2[nH]c3cnccc3c2c1 +c1ccc2c(c1)ccn2-c1cccc2c1sc1ccccc12 +c1ccc2c(c1)ccn2-c1cccc2ocnc12 +c1ccc2c(c1)ccn2-c1cccc2sc3ccccc3c12 +c1ccc2c(c1)ccn2-c1ccno1 +c1ccc2c(c1)ccn2-c1cnc2ccccc2n1 +c1ccc2c(c1)ccn2-c1cnc2[nH]c3ccccc3c2c1 +c1ccc2c(c1)ccn2-c1coc2nc3[nH]ccc3nc12 +c1ccc2c(c1)ccn2-c1nccc2c1[nH]c1ccccc12 +c1ccc2c(c1)cnc1c(-c3cc4[nH]c5ccccc5c4cn3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4c(c3)sc3ccccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4ccsc4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4cc[nH]c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4oc5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3ccc4scnc4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cccc4c3[nH]c3ncccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3cccc4c5ccccc5c5nccnc5c34)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4sc5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cnc4[nH]c5ccccc5c4c3)cccc12 +c1ccc2c(c1)cnc1c(-c3cn[nH]c3)cccc12 +c1ccc2c(c1)cnc1c(-c3coc4ccccc34)cccc12 +c1ccc2c(c1)cnc1c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc12 +c1ccc2c(c1)cnc1c(-n3ccc4nc5ccoc5nc43)cccc12 +c1ccc2c(c1)cnc1cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cc4cccnc4c4ncccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3ccncc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4c5c3CCCN5CCC4)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ccoc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ccsc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4sccc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3ccc4[nH]nnc4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c3sc3ncccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c3[nH]c3cnccc34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cccc4c5ccccc5c5[nH]cnc5c34)ccc12 +c1ccc2c(c1)cnc1cc(-c3cnc4c5ccccc5c5ccccc5c4n3)ccc12 +c1ccc2c(c1)cnc1cc(-c3cnc4sc5ncccc5c4c3)ccc12 +c1ccc2c(c1)cnc1cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1ccc2c(c1)cnc1cc(-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)ccc12 +c1ccc2c(c1)cnc1cc(-n3cnc4c5ccccc5c5ccccc5c43)ccc12 +c1ccc2c(c1)cnc1ccc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4c(cnc5ccccc54)c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4nn[nH]c4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4occc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4ocnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4[nH]ccc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4c3cnc3ccccc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4ncsc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4sc5ccccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3cccc4[nH]c5ncccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnc4c3ccc3cccnc34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnc4sc5ccccc5c34)cc12 +c1ccc2c(c1)cnc1ccc(-c3ccnnc3)cc12 +c1ccc2c(c1)cnc1ccc(-c3nc4cc5scnc5cc4s3)cc12 +c1ccc2c(c1)cnc1ccc(-c3nccs3)cc12 +c1ccc2c(c1)cnc1ccc(-n3ccc4cnccc43)cc12 +c1ccc2c(c1)cnc1ccc(-n3cnc4cc5nc[nH]c5cc43)cc12 +c1ccc2c(c1)cnc1cccc(-c3cc4cc5ccoc5cc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3cc4nc5ccoc5nc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4c(c3)sc3ccccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4c(n3)sc3ncccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4[nH]c5ccncc5c4c3)c12 +c1ccc2c(c1)cnc1cccc(-c3ccc4[nH]nnc4c3)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4c5ccccc5c5nccnc5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4ncc5ccccc5c34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4occc34)c12 +c1ccc2c(c1)cnc1cccc(-c3cccc4[nH]ccc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccnc4cccnc34)c12 +c1ccc2c(c1)cnc1cccc(-c3ccno3)c12 +c1ccc2c(c1)cnc1cccc(-c3cn[nH]c3)c12 +c1ccc2c(c1)cnc1cccc(-c3coc4cc5ccoc5cc34)c12 +c1ccc2c(c1)cnc1cccc(-c3coc4cc5[nH]ccc5cc34)c12 +c1ccc2c(c1)cnc1cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)cnc1cccc(-c3nc4cc5scnc5cc4s3)c12 +c1ccc2c(c1)cnc1cccc(-n3cnc4c5ccccc5c5ccccc5c43)c12 +c1ccc2c(c1)nc(-c1c3cc[nH]c3cc3occc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3ncoc3nc3ocnc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3ncsc3cc3ncsc13)c1ccccc12 +c1ccc2c(c1)nc(-c1c3nc[nH]c3cc3[nH]cnc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cc3c4ccccc4[nH]c3c3c1[nH]c1ccccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cc3nc4cc[nH]c4nc3o1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3c(c1)c1ccccc1c1nccnc31)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3c(c1)[nH]c1c3ccc3[nH]c4ccccc4c31)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3nccnc3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3nn[nH]c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1ccc3oc4ccccc4c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3c1[nH]c1ccncc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3c4ccccc4c4nc[nH]c4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3occc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3sccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cccc3[nH]c4ncccc4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1ccnc3oc4ccccc4c13)c1ccccc12 +c1ccc2c(c1)nc(-c1cnc3[nH]c4ccccc4c3c1)c1ccccc12 +c1ccc2c(c1)nc(-c1cncc3c1[nH]c1ccccc13)c1ccccc12 +c1ccc2c(c1)nc(-c1cn[nH]c1)c1ccccc12 +c1ccc2c(c1)nc(-n1c3ccncc3c3cnccc31)c1ccccc12 +c1ccc2c(c1)ncc1c(-c3c4ccoc4cc4ccoc34)cccc12 +c1ccc2c(c1)ncc1c(-c3c4ncoc4nc4ocnc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cc4cc5occc5cc4o3)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4c(n3)[nH]c3ccccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4nccnc4c3)cccc12 +c1ccc2c(c1)ncc1c(-c3ccc4ocnc4c3)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3oc3ncccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3sc3ncccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)cccc12 +c1ccc2c(c1)ncc1c(-c3cccc4[nH]nnc34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccnc4sc5ccccc5c34)cccc12 +c1ccc2c(c1)ncc1c(-c3ccnc4sc5ncccc5c34)cccc12 +c1ccc2c(c1)ncc1c(-c3cc[nH]n3)cccc12 +c1ccc2c(c1)ncc1c(-c3cnoc3)cccc12 +c1ccc2c(c1)ncc1c(-c3cscn3)cccc12 +c1ccc2c(c1)ncc1c(-c3c[nH]c4ccccc34)cccc12 +c1ccc2c(c1)ncc1c(-c3nc4cc5nc[nH]c5cc4[nH]3)cccc12 +c1ccc2c(c1)ncc1c(-c3nccs3)cccc12 +c1ccc2c(c1)ncc1c(-n3c4ccccc4c4c5ccccc5[nH]c43)cccc12 +c1ccc2c(c1)ncc1c(-n3c4ccccc4c4cccnc43)cccc12 +c1ccc2c(c1)ncc1c(-n3ccc4cc5ccoc5cc43)cccc12 +c1ccc2c(c1)ncc1c(-n3cnc4c5ccccc5c5ccccc5c43)cccc12 +c1ccc2c(c1)ncc1cc(-c3c4ccoc4cc4ccoc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3c4ncoc4cc4ncoc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3cc4[nH]c5ccccc5c4cn3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(c3)sc3ncccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c(cnc5ccccc54)c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4c5c3CCCN5CCC4)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]c5ccncc5c4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccc4[nH]ccc4c3)ccc12 +c1ccc2c(c1)ncc1cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3cccc4[nH]ccc34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccnc4sc5ccccc5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccnc4[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)ncc1cc(-c3ccon3)ccc12 +c1ccc2c(c1)ncc1cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +c1ccc2c(c1)ncc1ccc(-c3c4[nH]ccc4cc4ccoc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4ccsc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4ncsc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4occc4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5ncccc5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3sc3ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3[nH]c3cnccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c3[nH]c3ncccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3ccnc4oc5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cnc4c5ccccc5c5ccccc5c4n3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncc4c3[nH]c3ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncc4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)ncc1ccc(-c3cncs3)cc12 +c1ccc2c(c1)ncc1ccc(-c3cnoc3)cc12 +c1ccc2c(c1)ncc1ccc(-c3coc4ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3c[nH]c4ccccc34)cc12 +c1ccc2c(c1)ncc1ccc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)ncc1ccc(-c3ncno3)cc12 +c1ccc2c(c1)ncc1ccc(-n3c4ccccc4c4c5ccccc5[nH]c43)cc12 +c1ccc2c(c1)ncc1ccc(-n3c4ccccc4c4cccnc43)cc12 +c1ccc2c(c1)nnn2-c1cc2c3c(c1)CCCN3CCC2 +c1ccc2c(c1)nnn2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)nnn2-c1ccc2c(c1)sc1ccccc12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1ccc3c4ccccc4[nH]c3c12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1cnccc12 +c1ccc2c(c1)nnn2-c1ccc2c(c1)[nH]c1ncccc12 +c1ccc2c(c1)nnn2-c1ccc2cc[nH]c2c1 +c1ccc2c(c1)nnn2-c1ccc2ncoc2c1 +c1ccc2c(c1)nnn2-c1ccc2nn[nH]c2c1 +c1ccc2c(c1)nnn2-c1ccc2oc3ncccc3c2c1 +c1ccc2c(c1)nnn2-c1ccc2sc3ncccc3c2c1 +c1ccc2c(c1)nnn2-c1ccc2scnc2c1 +c1ccc2c(c1)nnn2-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +c1ccc2c(c1)nnn2-c1cccc2c1[nH]c1[nH]c3ccccc3c12 +c1ccc2c(c1)nnn2-c1cccc2c3ccccc3c3[nH]cnc3c12 +c1ccc2c(c1)nnn2-c1cccc2c3nc[nH]c3c3ccccc3c12 +c1ccc2c(c1)nnn2-c1cccc2[nH]c3ccncc3c12 +c1ccc2c(c1)nnn2-c1cnc2[nH]c3ccccc3c2c1 +c1ccc2c(c1)nnn2-c1cncc2[nH]c3ccccc3c12 +c1ccc2c(c1)nnn2-c1coc2cc3ccoc3cc12 +c1ccc2c(c1)nnn2-c1csc2ccccc12 +c1ccc2c(c1)nnn2-c1nc2cc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)nnn2-c1nc2cc3ocnc3cc2o1 +c1ccc2c(c1)nnn2-c1nccc2[nH]ccc12 +c1ccc2c(c1)nnn2-n1c2ccccc2c2c3[nH]c4ccccc4c3ccc21 +c1ccc2c(c1)nnn2-n1cccn1 +c1ccc2c(c1)nnn2-n1cnc2c3ccccc3c3ccccc3c21 +c1ccc2c(c1)nnn2-n1cnc2nc3nc[nH]c3nc21 +c1ccc2c(c1)oc1c(-c3c4ncoc4nc4ocnc34)cccc12 +c1ccc2c(c1)oc1c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc12 +c1ccc2c(c1)oc1c(-c3c4[nH]cnc4nc4nc[nH]c34)cccc12 +c1ccc2c(c1)oc1c(-c3cc4[nH]c5ccncc5c4cn3)cccc12 +c1ccc2c(c1)oc1c(-c3ccc4nn[nH]c4c3)cccc12 +c1ccc2c(c1)oc1c(-c3cncc4c3[nH]c3ccncc34)cccc12 +c1ccc2c(c1)oc1c(-c3csc4ccccc34)cccc12 +c1ccc2c(c1)oc1c(-c3c[nH]c4nc5occc5nc34)cccc12 +c1ccc2c(c1)oc1c(-n3ccc4cnccc43)cccc12 +c1ccc2c(c1)oc1cc(-c3cc4cnccc4[nH]3)ccc12 +c1ccc2c(c1)oc1cc(-c3ccc(-c4cnccn4)cc3)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccc4c(n3)oc3ccccc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4c5c3CCCN5CCC4)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4c5ccccc5c5[nH]cnc5c4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4oc5ncccc5c4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4ocnc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3ccc4scnc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3ccc4[nH]c5ncccc5c4c3)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccc4[nH]ccc4c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cccc4ccsc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3ccnc4ncccc34)ccc12 +c1ccc2c(c1)Oc1cc(-c3ccnc4oc5ccccc5c34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3cc[nH]n3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3cncs3)ccc12 +c1ccc2c(c1)Oc1cc(-c3cn[nH]c3)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1cc(-c3csc4ccccc34)cc3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1cc(-c3c[nH]c4nc5occc5nc34)ccc12 +c1ccc2c(c1)oc1cc(-c3nc4cc5nc[nH]c5cc4[nH]3)ccc12 +c1ccc2c(c1)oc1cc(-c3ncon3)ccc12 +c1ccc2c(c1)oc1cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +c1ccc2c(c1)Oc1ccc(-c3c4ncoc4cc4ncoc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3c4ncoc4nc4ocnc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3c4[nH]cnc4nc4nc[nH]c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cc4c5c(c3)Oc3ccccc3B5c3ccccc3O4)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cc4cc5ccoc5cc4[nH]3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)oc1ccc(-c3cc4cnccc4[nH]3)cc12 +c1ccc2c(c1)oc1ccc(-c3cc4[nH]c5ccncc5c4cn3)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3ccc4ccoc4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3ccc4ncc5ccccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccc4sccc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3ccc4[nH]c5cnccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccc4[nH]c5ncccc5c4c3)cc12 +c1ccc2c(c1)oc1ccc(-c3cccc4c3[nH]c3cnccc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3cccc4c3[nH]c3cnccc34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cccc4ncc5ccccc5c34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cccc4ncoc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cccc4nn[nH]c34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3cccc4sc5ccccc5c34)cc12 +c1ccc2c(c1)Oc1ccc(-c3ccnc4cccnc34)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3ccnc4sc5ncccc5c34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3ccno3)cc12 +c1ccc2c(c1)Oc1ccc(-c3cc[nH]n3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cnc4cccnc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4ncccc4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4nccnc4n3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3cnc4sc5ccccc5c4c3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3cnc4[nH]c5ccccc5c4c3)cc1O2 +c1ccc2c(c1)Oc1ccc(-c3c[nH]c4nc5occc5nc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)oc1ccc(-c3c[nH]c4nc5occc5nc34)cc12 +c1ccc2c(c1)Oc1ccc(-c3nc4ccccc4s3)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3nccc4c3[nH]c3ccccc34)c3c1B2c1ccccc1O3 +c1ccc2c(c1)Oc1ccc(-c3nccc4[nH]ccc34)cc1O2 +c1ccc2c(c1)oc1ccc(-c3ncno3)cc12 +c1ccc2c(c1)Oc1ccc(-n3c4ccncc4c4cnccc43)cc1O2 +c1ccc2c(c1)oc1cccc(-c3c4ccoc4cc4ccoc34)c12 +c1ccc2c(c1)Oc1cccc(-c3cc4nc5cc[nH]c5nc4o3)c1O2 +c1ccc2c(c1)oc1cccc(-c3cc4[nH]c5ccncc5c4cn3)c12 +c1ccc2c(c1)oc1cccc(-c3cc4[nH]ccc4cn3)c12 +c1ccc2c(c1)Oc1cccc(-c3ccc4c(n3)[nH]c3ccccc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccc4ccsc4c3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccc4ncc5ccccc5c4c3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)Oc1cccc(-c3ccc4[nH]c5cnccc5c4c3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cccc4ocnc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cccc4sccc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3ccccc3-c3cnccn3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ccnc4ncccc34)c12 +c1ccc2c(c1)oc1cccc(-c3ccon3)c12 +c1ccc2c(c1)Oc1cccc(-c3cncc4c3[nH]c3ccncc34)c1O2 +c1ccc2c(c1)Oc1cccc(-c3cscn3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3nc4nc5nc[nH]c5cc4[nH]3)c1O2 +c1ccc2c(c1)Oc1cccc(-c3nc4nc5ocnc5nc4o3)c1O2 +c1ccc2c(c1)oc1cccc(-c3ncon3)c12 +c1ccc2c(c1)oc1cccc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)Oc1cccc(-n3cnc4nc5nc[nH]c5nc43)c1O2 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cc2c(cn1)[nH]c1ccccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cc2ccccc2o1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2c(c1)[nH]c1c2ccc2[nH]c4ccccc4c21)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2nn[nH]c2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2oc4ccccc4c2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccc2[nH]ccc2c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c1oc1ccccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c1oc1ncccc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2c4ccccc4c4nc[nH]c4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2oc4ncccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2[nH]c4cnccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cccc2[nH]c4[nH]c5ccccc5c4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccccc1-c1cc2c4c(c1)CCCN4CCC2)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1ccnc2sc4ncccc4c12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1cn[nH]c1)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-c1c[nH]c2cc4occc4cc12)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1c(cccc1-n1c2ccccc2c2cnccc21)O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(c2)oc2ccccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(n2)sc2ccccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4c(n2)sc2ncccc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2ccc4ncsc4c2)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4c5ccccc5c5nc[nH]c5c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4ncc5ccccc5c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4nn[nH]c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cc(-c2coc4cc5ccoc5cc24)ccc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4cc5ccoc5cc4[nH]2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4cc5occc5cc4o2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4ccccc4s2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2ccc4c(c2)[nH]c2[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2ncc2ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2oc2ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2[nH]c2c4ccc4[nH]c5ccccc5c42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c2[nH]c2ccncc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cccc4c5ccccc5c5nc[nH]c5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cc[nH]n2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2cncc4[nH]c5ccccc5c24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2coc4cc5ccoc5cc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2coc4ccccc24)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-c2nc4ccccc4s2)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2c4ccccc4c4c5ccccc5[nH]c42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2c4ccncc4c4cnccc42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1ccc(-n2ccc4nc5ccoc5nc42)cc1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccc4c(c2)[nH]c2c4ccc4[nH]c5ccccc5c42)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4oc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4ocnc24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4sc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cccc4[nH]ccc24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2ccnc4sc5ncccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2cc[nH]n2)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-c2nccc4[nH]c5ccccc5c24)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-n2c4ccncc4c4cnccc42)c1O3 +c1ccc2c(c1)Oc1cccc3c1B2c1cccc(-n2cnc4c5ccccc5c5ccccc5c42)c1O3 +c1ccc2c(c1)oc1nc(-c3cc4cnccc4[nH]3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc(-c4cnccn4)cc3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4sc5ccccc5c4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3ccc4[nH]c5ncccc5c4c3)ccc12 +c1ccc2c(c1)oc1nc(-c3cccc4c3sc3ccccc34)ccc12 +c1ccc2c(c1)oc1nc(-c3nccs3)ccc12 +c1ccc2c(c1)oc1ncc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)oc1ncc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)oc1ncc(-c3cc4nc5ccoc5nc4[nH]3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccc4[nH]c5cnccc5c4c3)cc12 +c1ccc2c(c1)oc1ncc(-c3ccno3)cc12 +c1ccc2c(c1)oc1ncc(-c3cnc4nccnc4n3)cc12 +c1ccc2c(c1)oc1ncc(-c3nc4cc5ncoc5nc4o3)cc12 +c1ccc2c(c1)oc1ncc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)oc1ncc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)oc1nccc(-c3c4[nH]cnc4nc4nc[nH]c34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4c(c3)[nH]c3ncccc34)c12 +c1ccc2c(c1)oc1nccc(-c3ccc4ocnc4c3)c12 +c1ccc2c(c1)oc1nccc(-c3cncc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)oc1nccc(-c3ncno3)c12 +c1ccc2c(c1)oc1nccc(-n3ccc4nc5ccoc5nc43)c12 +c1ccc2c(c1)oc1nccc(-n3cnc4cc5nc[nH]c5cc43)c12 +c1ccc2c(c1)sc1c(-c3c4[nH]ccc4cc4ccoc34)cccc12 +c1ccc2c(c1)sc1c(-c3cc4c5c(c3)CCCN5CCC4)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4c(c3)c3ccccc3c3nccnc43)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4ccoc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4occc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3ccc4[nH]nnc4c3)cccc12 +c1ccc2c(c1)sc1c(-c3cccc4c3[nH]c3ccncc34)cccc12 +c1ccc2c(c1)sc1c(-c3cc[nH]n3)cccc12 +c1ccc2c(c1)sc1c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +c1ccc2c(c1)sc1c(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cccc12 +c1ccc2c(c1)sc1c(-c3nc4cc5scnc5cc4s3)cccc12 +c1ccc2c(c1)sc1c(-c3nccc4[nH]c5ccncc5c34)cccc12 +c1ccc2c(c1)sc1c(-n3c4ccccc4c4ccncc43)cccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ccsc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ncoc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4nn[nH]c4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4scnc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3ccc4[nH]ccc4c3)ccc12 +c1ccc2c(c1)sc1cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)ccc12 +c1ccc2c(c1)sc1cc(-c3cccc4c5[nH]cnc5c5ccccc5c34)ccc12 +c1ccc2c(c1)sc1cc(-c3cn[nH]c3)ccc12 +c1ccc2c(c1)sc1cc(-c3nccc4[nH]c5ccncc5c34)ccc12 +c1ccc2c(c1)sc1ccc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4c(n3)sc3ccccc34)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4c(n3)sc3ncccc34)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)sc1ccc(-c3ccc4[nH]c5ccncc5c4c3)cc12 +c1ccc2c(c1)sc1ccc(-c3cccc4c5nc[nH]c5c5ccccc5c34)cc12 +c1ccc2c(c1)sc1ccc(-n3c4ccncc4c4cnccc43)cc12 +c1ccc2c(c1)sc1cccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)c12 +c1ccc2c(c1)sc1cccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)sc1cccc(-c3cccc4c5nccnc5c5ccccc5c34)c12 +c1ccc2c(c1)sc1cccc(-c3c[nH]c4nc5occc5nc34)c12 +c1ccc2c(c1)sc1cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c12 +c1ccc2c(c1)sc1cccc(-n3c4ccncc4c4cnccc43)c12 +c1ccc2c(c1)sc1nc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +c1ccc2c(c1)sc1nc(-c3ccc4ocnc4c3)ccc12 +c1ccc2c(c1)sc1nc(-c3ccc4[nH]nnc4c3)ccc12 +c1ccc2c(c1)sc1nc(-c3ccno3)ccc12 +c1ccc2c(c1)sc1nc(-c3cnc4nccnc4n3)ccc12 +c1ccc2c(c1)sc1nc(-c3cnoc3)ccc12 +c1ccc2c(c1)sc1nc(-c3nc4nc5nc[nH]c5nc4[nH]3)ccc12 +c1ccc2c(c1)sc1nc(-c3nccc4[nH]c5ccncc5c34)ccc12 +c1ccc2c(c1)sc1nc(-c3nccc4[nH]ccc34)ccc12 +c1ccc2c(c1)sc1ncc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)sc1ncc(-c3c4[nH]cnc4cc4nc[nH]c34)cc12 +c1ccc2c(c1)sc1ncc(-c3cc4cc5occc5cc4o3)cc12 +c1ccc2c(c1)sc1ncc(-c3ccc4nccnc4c3)cc12 +c1ccc2c(c1)sc1ncc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)sc1ncc(-c3nc4nc5nc[nH]c5nc4[nH]3)cc12 +c1ccc2c(c1)sc1ncc(-c3ncno3)cc12 +c1ccc2c(c1)sc1ncc(-n3cnc4cc5nc[nH]c5cc43)cc12 +c1ccc2c(c1)sc1ncc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)sc1nccc(-c3c4nc[nH]c4cc4[nH]cnc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccc(-c4cnccn4)cc3)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4ncoc4c3)c12 +c1ccc2c(c1)sc1nccc(-c3ccc4ocnc4c3)c12 +c1ccc2c(c1)sc1nccc(-c3cccc4c3[nH]c3ncccc34)c12 +c1ccc2c(c1)sc1nccc(-c3ccon3)c12 +c1ccc2c(c1)sc1nccc(-c3cnc4nccnc4n3)c12 +c1ccc2c(c1)sc1nccc(-c3nc4cc5ncoc5nc4o3)c12 +c1ccc2c(c1)sc1nccc(-n3c4ccccc4c4ccncc43)c12 +c1ccc2c(c1)sc1nccc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)sc1nccc(-n3cnc4nc5nc[nH]c5nc43)c12 +c1ccc2c(c1)[nH]c1c(-c3c4cc[nH]c4cc4occc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cc4cc5occc5cc4o3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cc4[nH]ccc4cn3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4c(c3)[nH]c3ncccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4c(n3)sc3ccccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4ccoc4c3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4ccsc4c3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccc4[nH]nnc4c3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4c3[nH]c3ncccc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4c5[nH]cnc5c5ccccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cccc4[nH]c5ncccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccnc4oc5ccccc5c34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ccnc4[nH]c5ccccc5c34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3ccnnc3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3cncs3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3coc4cc5[nH]ccc5cc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3coc4nc5[nH]ccc5nc34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3cscn3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3c[nH]c4ccncc34)cncc12 +c1ccc2c(c1)[nH]c1c(-c3c[nH]c4nc5occc5nc34)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nc4cc5nc[nH]c5cc4[nH]3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3nc4cc5ocnc5cc4o3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nc4nc5nc[nH]c5cc4[nH]3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3nccs3)cncc12 +c1ccc2c(c1)[nH]c1c(-c3nccs3)nccc12 +c1ccc2c(c1)[nH]c1c(-c3ncon3)cncc12 +c1ccc2c(c1)[nH]c1c(-n3cnc4nc5nc[nH]c5cc43)nccc12 +c1ccc2c(c1)[nH]c1c2c(-c2c3[nH]cnc3cc3nc[nH]c23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2ccc3ccsc3c2)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2cccc3c2sc2ccccc23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2cccc3[nH]c4ncccc4c23)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-c2nccs2)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-n2ccc3cnccc32)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c(-n2cnc3nc4nc[nH]c4nc32)cc2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1c2[nH]cnc2nc2nc[nH]c12 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1ccno1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1ccon1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cnc2nccnc2n1 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cncc2c1[nH]c1ccncc12 +c1ccc2c(c1)[nH]c1c2c2ccccc2n1-c1cscn1 +c1ccc2c(c1)[nH]c1c2cc(-c2c3[nH]cnc3cc3nc[nH]c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3c(c2)[nH]c2cnccc23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3c(c2)[nH]c2ncccc23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3ccsc3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3nccnc3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccc3nn[nH]c3c2)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2ccnc3[nH]c4ccccc4c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-c2cncc3cc[nH]c23)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2cc(-n2cnc3nc4nc[nH]c4nc32)c2[nH]c3ccccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cc2[nH]ccc2cn1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccc2[nH]nnc2c1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cccc2c1sc1ccccc12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccnc2ncccc12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ccno1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cncc2cc[nH]c12 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1cncs1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1nc2nc3nc[nH]c3cc2[nH]1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1nc2nc3ocnc3nc2o1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-c1ncon1 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-n1cnc2cc3nc[nH]c3cc21 +c1ccc2c(c1)[nH]c1c2ccc2c1c1ccccc1n2-n1cnc2nc3nc[nH]c3cc21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4c5ncoc5nc5ocnc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ccc5c(c4)sc4ccccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ccc5sccc5c4)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4cccc5c4[nH]c4cnccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4cccc5[nH]c6cnccc6c45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4csc5ccccc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4c[nH]c5ccncc45)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-c4ncno4)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3c(-n4ccc5nc6ccoc6nc54)cccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cc5cc6occc6cc5o4)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cccc5ocnc45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cccc5[nH]c6cnccc6c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4ccnc5ncccc45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4ccnc5[nH]c6ccccc6c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4cncc5cc[nH]c45)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-c4nccs4)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-n4c5ccncc5c5cnccc54)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4c5ccoc5cc5ccoc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4ccc5[nH]c6cnccc6c5c4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5c4[nH]c4ncccc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5sc6ccccc6c45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cccc5[nH]c6ncccc6c45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cncc5c4[nH]c4ccncc45)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cncs4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cnoc4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4cscn4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4nc5nc6nc[nH]c6cc5[nH]4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-c4ncon4)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-n4c5ccccc5c5ccncc54)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccc(-n4ccc5nc6ccoc6nc54)cc3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cc5nc6ccoc6nc5[nH]4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4ccc5ccsc5c4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4ccc5ncoc5c4)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cccc5c4[nH]c4ncccc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4cncc5c4[nH]c4ccncc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-c4csc5ccccc45)c3c21 +c1ccc2c(c1)[nH]c1c2ccc2[nH]c3cccc(-n4cnc5nc6nc[nH]c6nc54)c3c21 +c1ccc2c(c1)[nH]c1cc(-c3cc4cc5occc5cc4o3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3ccc4ncoc4c3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3ccc4ocnc4c3)ncc12 +c1ccc2c(c1)[nH]c1cc(-c3cncc4cc[nH]c34)ncc12 +c1ccc2c(c1)[nH]c1cc(-n3c4ccccc4c4ccncc43)ncc12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5cc6[nH]ccc6cn5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccc6c(c5)[nH]c5cnccc56)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccc6ccsc6c5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccno5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5ccon5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c([nH]c4cccc(-c5nccs5)c43)c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cc6nc7ccoc7nc6[nH]5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5ccc6ccsc6c5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5sc5ccccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5[nH]c5cnccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cccc6c5[nH]c5ncccc56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5cnoc5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5nc6nc7nc[nH]c7nc6[nH]5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5nccc6[nH]c7ccncc7c56)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-c5ncon5)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cc(-n5cnc6nc7nc[nH]c7cc65)ccc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5cccc6sccc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5cncc6c5[nH]c5ccncc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-c5coc6cc7ccoc7cc56)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-n5c6ccncc6c6cnccc65)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccc(-n5ccc6cnccc65)cc4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5c6nc[nH]c6cc6[nH]cnc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5c6[nH]cnc6nc6nc[nH]c56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6c(c5)sc5ccccc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6nn[nH]c6c5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ccc6[nH]nnc6c5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5cccc6sccc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5coc6nc7[nH]ccc7nc56)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-c5ncno5)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-n5cnc6cc7nc[nH]c7cc65)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4cccc(-n5cnc6nc7nc[nH]c7cc65)c4[nH]c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4c5ncoc5nc5ocnc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4cc5cnccc5[nH]4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5c(c4)[nH]c4cnccc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5[nH]c6ncccc6c5c4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4ccc5[nH]nnc5c4)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-c4csc5ccccc45)c3c12 +c1ccc2c(c1)[nH]c1ccc3c4ccccc4n(-n4cnc5cc6nc[nH]c6cc54)c3c12 +c1ccc2c(c1)[nH]c1ccnc(-c3c4nc[nH]c4cc4[nH]cnc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccc4c(c3)[nH]c3cnccc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cccc4c3sc3ccccc34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cccc4[nH]c5cnccc5c34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccnc4[nH]c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3ccno3)c12 +c1ccc2c(c1)[nH]c1ccnc(-c3cscn3)c12 +c1ccc2c(c1)[nH]c1ccnc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)[nH]c1cnc(-c3c4nc[nH]c4cc4[nH]cnc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cc4c5c(c3)CCCN5CCC4)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)oc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)sc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(c3)sc3ncccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c(n3)[nH]c3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4c5ccccc5c5nccnc5c4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4ccsc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4sc5ccccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4sccc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccc4scnc4c3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4c3oc3ccccc34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ccnc4sc5ncccc5c34)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3cnc4nccnc4n3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cc12 +c1ccc2c(c1)[nH]c1cnc(-c3ncno3)cc12 +c1ccc2c(c1)[nH]c1cnc(-n3c4ccncc4c4cnccc43)cc12 +c1ccc2c(c1)[nH]c1cnc(-n3cnc4nc5nc[nH]c5nc43)cc12 +c1ccc2c(c1)[nH]c1cncc(-c3c4ncoc4nc4ocnc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cc4cc5occc5cc4o3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cc4[nH]ccc4cn3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4c(c3)c3ccccc3c3nccnc43)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4c(c3)sc3ccccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4ccsc4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4cc[nH]c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4oc5ccccc5c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4[nH]c5ccncc5c4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3ccc4[nH]ccc4c3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cccc4c3[nH]c3ncccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cccc4scnc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cncs3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3csc4ccccc34)c12 +c1ccc2c(c1)[nH]c1cncc(-c3cscn3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)[nH]c1cncc(-c3nc4nc5nc[nH]c5cc4[nH]3)c12 +c1ccc2c(c1)[nH]c1cncc(-n3c4ccccc4c4cccnc43)c12 +c1ccc2c(c1)[nH]c1cncc(-n3cnc4nc5nc[nH]c5cc43)c12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4c(n3)sc3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccc4oc5ncccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4c3oc3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4occc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4ocnc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3ccnc4sc5ncccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cnc4sc5ccccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3cnc4sc5ncccc5c4c3)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3coc4nc5[nH]ccc5nc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3nccc4c3[nH]c3ccccc34)ccc12 +c1ccc2c(c1)[nH]c1nc(-c3nccc4[nH]c5ccccc5c34)ccc12 +c1ccc2c(c1)[nH]c1nc(-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)ccc12 +c1ccc2c(c1)[nH]c1ncc(-c3c4ncoc4cc4ncoc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c(c3)[nH]c3ccncc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4c5ccccc5c5nccnc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4ncsc4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4sc5ncccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3ccc4[nH]nnc4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cnc4oc5ccccc5c4c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cncc4[nH]c5ccccc5c34)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3cn[nH]c3)cc12 +c1ccc2c(c1)[nH]c1ncc(-c3coc4nc5[nH]ccc5nc34)cc12 +c1ccc2c(c1)[nH]c1ncc(-n3ccc4nc5ccoc5nc43)cc12 +c1ccc2c(c1)[nH]c1ncc(-n3cccn3)cc12 +c1ccc2c(c1)[nH]c1nccc(-c3cc4cc5occc5cc4o3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4cc[nH]c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c3oc3ccccc34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4occc34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cccc4[nH]c5cnccc5c34)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cnc4oc5ccccc5c4c3)c12 +c1ccc2c(c1)[nH]c1nccc(-c3cncc4c3[nH]c3ccncc34)c12 +c1ccc2c(c1)[nH]c1nccc(-n3c4ccccc4c4c5ccccc5[nH]c43)c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4c5[nH]cnc5cc5nc[nH]c45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cc5cnccc5[nH]4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4ccc5c(c4)[nH]c4cnccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4ccc5c(c4)[nH]c4ncccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cccc5sccc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4coc5nc6[nH]ccc6nc45)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4cscn4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3c(-c4nc5nc6nc[nH]c6cc5[nH]4)cccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4cc5[nH]ccc5cn4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5c(c4)sc4ccccc45)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5nn[nH]c5c4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4ccc5[nH]c6ncccc6c5c4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4coc5cc6ccoc6cc45)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5cc6ncoc6nc5o4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5cc6nc[nH]c6cc5[nH]4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cc(-c4nc5nc6nc[nH]c6cc5[nH]4)ccc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nc5cc6nc[nH]c6cc5[nH]4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nc5nc6ocnc6nc5o4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4nccs4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-c4ncon4)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3ccc(-n4c5ccccc5c5cccnc54)cc3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5nccnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5ocnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4ccc5[nH]nnc5c4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4cnoc4)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-c4coc5nc6[nH]ccc6nc45)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-n4c5ccncc5c5cnccc54)c3c12 +c1ccc2c(c1)[nH]c1[nH]c3cccc(-n4cnc5nc6nc[nH]c6cc54)c3c12 +c1ccc2nc(-c3ccc4c5ccccc5c5nccnc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4cnc5ccccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4ncsc4c3)cnc2c1 +c1ccc2nc(-c3ccc4oc5ccccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4sc5ncccc5c4c3)cnc2c1 +c1ccc2nc(-c3ccc4[nH]ccc4c3)cnc2c1 +c1ccc2nc(-c3cccc4c3sc3ncccc34)cnc2c1 +c1ccc2nc(-c3cccc4c3[nH]c3cnccc34)cnc2c1 +c1ccc2nc(-c3cccc4ncoc34)cnc2c1 +c1ccc2nc(-c3cccc4ocnc34)cnc2c1 +c1ccc2nc(-c3cccc4[nH]c5cnccc5c34)cnc2c1 +c1ccc2nc(-c3coc4cc5[nH]ccc5cc34)cnc2c1 +c1ccc2nc(-c3c[nH]c4cc5occc5cc34)cnc2c1 +c1ccc2nc(-n3c4ccccc4c4cnccc43)cnc2c1 +c1ccc2nc(-n3ccc4cc5ccoc5cc43)cnc2c1 +c1ccc2nc(-n3cccn3)cnc2c1 +c1ccc2oc(-c3c4nc[nH]c4cc4[nH]cnc34)cc2c1 +c1ccc2oc(-c3cc4c(cn3)[nH]c3ccccc34)cc2c1 +c1ccc2oc(-c3cc4c(cn3)[nH]c3ccccc34)nc2c1 +c1ccc2oc(-c3cc4cc5occc5cc4o3)cc2c1 +c1ccc2oc(-c3cc4nc5ccoc5nc4[nH]3)nc2c1 +c1ccc2oc(-c3ccc(-c4cnccn4)cc3)nc2c1 +c1ccc2oc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)nc2c1 +c1ccc2oc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)nc2c1 +c1ccc2oc(-c3ccc4c(c3)[nH]c3cnccc34)nc2c1 +c1ccc2oc(-c3ccc4c(n3)oc3ccccc34)nc2c1 +c1ccc2oc(-c3ccc4c(n3)sc3ncccc34)nc2c1 +c1ccc2oc(-c3ccc4ccsc4c3)nc2c1 +c1ccc2oc(-c3ccc4cc[nH]c4c3)nc2c1 +c1ccc2oc(-c3ccc4cnc5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3ccc4ncccc4n3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5cnccc5c4c3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5ncccc5c4c3)cc2c1 +c1ccc2oc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)nc2c1 +c1ccc2oc(-c3cccc4c5nc[nH]c5c5ccccc5c34)nc2c1 +c1ccc2oc(-c3cccc4oc5ccccc5c34)nc2c1 +c1ccc2oc(-c3cccc4ocnc34)nc2c1 +c1ccc2oc(-c3cccc4sccc34)nc2c1 +c1ccc2oc(-c3cccc4[nH]c5ccncc5c34)nc2c1 +c1ccc2oc(-c3cccc4[nH]c5ncccc5c34)cc2c1 +c1ccc2oc(-c3cccc4[nH]c5ncccc5c34)nc2c1 +c1ccc2oc(-c3ccn[nH]3)nc2c1 +c1ccc2oc(-c3cnc4ccccc4n3)cc2c1 +c1ccc2oc(-c3cnc4oc5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3cnc4[nH]c5ccccc5c4c3)nc2c1 +c1ccc2oc(-c3c[nH]c4ccccc34)nc2c1 +c1ccc2oc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)nc2c1 +c1ccc2oc(-c3ncon3)cc2c1 +c1ccc2oc(-n3cnc4nc5nc[nH]c5cc43)cc2c1 +c1ccc2oc(-n3nnc4ccccc43)nc2c1 +c1ccc2sc(-c3c4ncoc4cc4ncoc34)cc2c1 +c1ccc2sc(-c3ccc4c(c3)oc3ncccc34)cc2c1 +c1ccc2sc(-c3ccc4c(c3)sc3ncccc34)cc2c1 +c1ccc2sc(-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)cc2c1 +c1ccc2sc(-c3ccc4[nH]nnc4c3)nc2c1 +c1ccc2sc(-c3cccc4c3sc3ccccc34)nc2c1 +c1ccc2sc(-c3cccc4occc34)cc2c1 +c1ccc2sc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)cc2c1 +c1ccc2sc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)cc2c1 +c1ccc2sc(-c3ccnc4sc5ncccc5c34)cc2c1 +c1ccc2sc(-c3cnc4c5ccccc5c5ccccc5c4n3)cc2c1 +c1ccc2sc(-c3cnc4cccnc4c3)cc2c1 +c1ccc2sc(-c3c[nH]c4ccccc34)cc2c1 +c1ccc2sc(-c3c[nH]c4ccncc34)nc2c1 +c1ccc2sc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)cc2c1 +c1ccc2sc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc2c1 +c1ccc2sc(-c3nc4nc5nc[nH]c5nc4[nH]3)nc2c1 +c1ccc2sc(-c3nccc4[nH]ccc34)cc2c1 +c1ccc2sc(-n3ccc4cc5ccoc5cc43)cc2c1 +c1ccc2[nH]c(-c3c4ncoc4nc4ocnc34)cc2c1 +c1ccc2[nH]c(-c3cc4cccnc4c4ncccc34)cc2c1 +c1ccc2[nH]c(-c3cc4cnccc4[nH]3)cc2c1 +c1ccc2[nH]c(-c3cc4nc5ccoc5nc4[nH]3)cc2c1 +c1ccc2[nH]c(-c3ccc(-c4cnccn4)cc3)cc2c1 +c1ccc2[nH]c(-c3ccc4c(cnc5ccccc54)c3)cc2c1 +c1ccc2[nH]c(-c3ccc4ocnc4c3)cc2c1 +c1ccc2[nH]c(-c3cccc4c3[nH]c3cnccc34)cc2c1 +c1ccc2[nH]c(-c3cccc4c3[nH]c3ncccc34)cc2c1 +c1ccc2[nH]c(-c3cccc4[nH]c5cnccc5c34)cc2c1 +c1ccc2[nH]c(-c3cccc4[nH]nnc34)cc2c1 +c1ccc2[nH]c(-n3cnc4nc5nc[nH]c5nc43)cc2c1 +c1cnc(-c2ccc(-c3cc4cc5occc5cc4o3)cc2)cn1 +c1cnc(-c2ccc(-c3ccc4[nH]c5ccncc5c4c3)cc2)cn1 +c1cnc(-c2ccc(-n3cnc4nc5nc[nH]c5nc43)cc2)cn1 +c1cnc2c(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3ccncc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3cnccc34)ccnc2c1 +c1cnc2c(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccnc2c1 +c1cnc2c(-c3ccc4c5ccccc5c5[nH]cnc5c4c3)ccnc2c1 +c1cnc2c(-c3ccc4ccsc4c3)ccnc2c1 +c1cnc2c(-c3ccc4cc[nH]c4c3)ccnc2c1 +c1cnc2c(-c3ccc4sccc4c3)ccnc2c1 +c1cnc2c(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)ccnc2c1 +c1cnc2c(-c3ccc4[nH]nnc4c3)ccnc2c1 +c1cnc2c(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)ccnc2c1 +c1cnc2c(-c3cccc4c3[nH]c3cnccc34)ccnc2c1 +c1cnc2c(-c3cccc4c5ccccc5c5nccnc5c34)ccnc2c1 +c1cnc2c(-c3cccc4ncoc34)ccnc2c1 +c1cnc2c(-c3cnc4oc5ccccc5c4c3)ccnc2c1 +c1cnc2c(-c3cncc4c3[nH]c3ccccc34)ccnc2c1 +c1cnc2c(-n3c4ccncc4c4cnccc43)ccnc2c1 +c1cnc2c(c1)cc(-c1c3ncoc3cc3ncoc13)c1cccnc12 +c1cnc2c(c1)cc(-c1c3[nH]ccc3cc3ccoc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cc3nc4ccoc4nc3[nH]1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3c4ccccc4c4nc[nH]c4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3oc4ccccc4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3ocnc3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3sccc3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1ccc3[nH]c4[nH]c5ccccc5c4c3c1)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3c1cnc1ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3c4nccnc4c4ccccc4c13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3ocnc13)c1cccnc12 +c1cnc2c(c1)cc(-c1cccc3[nH]c4[nH]c5ccccc5c4c13)c1cccnc12 +c1cnc2c(c1)cc(-c1cncc3c1[nH]c1ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1nc3ccccc3c3ccccc13)c1cccnc12 +c1cnc2c(c1)cc(-c1nc3ccccc3s1)c1cccnc12 +c1cnc2c(c1)cc(-n1c3ccccc3c3c4[nH]c5ccccc5c4ccc31)c1cccnc12 +c1cnc2c(c1)cc(-n1nnc3ccccc31)c1cccnc12 +c1cnc2c(c1)ccc1c(-c3cc4cc5occc5cc4o3)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccc4c(cnc5ccccc54)c3)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4cnc5ccccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4ncoc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4oc5ncccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4sc5ncccc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]c5ccncc5c34)ccnc12 +c1cnc2c(c1)ccc1c(-c3cccc4[nH]ccc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3ccnnc3)ccnc12 +c1cnc2c(c1)ccc1c(-c3cncc4c3[nH]c3ccncc34)ccnc12 +c1cnc2c(c1)ccc1c(-c3nc4cc5ocnc5cc4o3)ccnc12 +c1cnc2c(c1)ccc1c(-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)ccnc12 +c1cnc2c(c1)ccc1cc(-c3c4ncsc4cc4ncsc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3c4[nH]ccc4cc4ccoc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c5c3CCCN5CCC4)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4c5ccccc5c5nccnc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4ncsc4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4sccc4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccc4[nH]c5ccncc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3cccc4[nH]c5ccncc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cccc4[nH]c5cnccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3ccnc4sc5ccccc5c34)cnc12 +c1cnc2c(c1)ccc1cc(-c3cnc4sc5ncccc5c4c3)cnc12 +c1cnc2c(c1)ccc1cc(-c3c[nH]c4ccccc34)cnc12 +c1cnc2c(c1)ccc1cc(-n3ccc4ccccc43)cnc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4cnc5ccccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4ocnc4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4sc5ncccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccc4[nH]c5cnccc5c4c3)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4c3[nH]c3ccncc34)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4nn[nH]c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3cccc4[nH]c5[nH]c6ccccc6c5c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3ccnc4sc5ncccc5c34)nc12 +c1cnc2c(c1)ccc1ccc(-c3coc4ccccc34)nc12 +c1cnc2c(c1)ccc1ccc(-c3nc4c5ccccc5c5ccccc5c4[nH]3)nc12 +c1cnc2c(c1)ccc1ccc(-c3nc4ccccc4o3)nc12 +c1cnc2c(c1)ccc1ccc(-n3ccc4cc5ccoc5cc43)nc12 +c1cnc2c(c1)ccc1ccc(-n3ccc4ccccc43)nc12 +c1cnc2c(c1)ccc1ccc(-n3nnc4ccccc43)nc12 +c1cnc2cc(-c3c4ncoc4cc4ncoc34)ccc2n1 +c1cnc2cc(-c3c4ncoc4cc4ncoc34)cnc2c1 +c1cnc2cc(-c3c4[nH]ccc4cc4ccoc34)ccc2n1 +c1cnc2cc(-c3cc4cc5ccoc5cc4[nH]3)ccc2n1 +c1cnc2cc(-c3cc4nc5ccoc5nc4[nH]3)cnc2c1 +c1cnc2cc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)cnc2c1 +c1cnc2cc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)cnc2c1 +c1cnc2cc(-c3ccc4occc4c3)cnc2c1 +c1cnc2cc(-c3ccc4ocnc4c3)ccc2n1 +c1cnc2cc(-c3cccc4c5ccccc5c5nc[nH]c5c34)cnc2c1 +c1cnc2cc(-c3cccc4ncoc34)cnc2c1 +c1cnc2cc(-c3cncc4[nH]c5ccccc5c34)cnc2c1 +c1cnc2cc(-c3coc4nc5[nH]ccc5nc34)ccc2n1 +c1cnc2cc(-c3coc4nc5[nH]ccc5nc34)cnc2c1 +c1cnc2cc(-c3nc4ccccc4s3)cnc2c1 +c1cnc2cc(-c3nccc4[nH]c5ccccc5c34)cnc2c1 +c1cnc2cc(-n3ccc4nc5ccoc5nc43)ccc2n1 +c1cnc2ccc(-c3c4ccoc4cc4ccoc34)nc2c1 +c1cnc2ccc(-c3c4cc[nH]c4cc4occc34)nc2c1 +c1cnc2ccc(-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)nc2c1 +c1cnc2ccc(-c3ccc4nn[nH]c4c3)nc2c1 +c1cnc2ccc(-c3ccc4oc5ncccc5c4c3)nc2c1 +c1cnc2ccc(-c3ccc4scnc4c3)nc2c1 +c1cnc2ccc(-c3ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c3)nc2c1 +c1cnc2ccc(-c3ccc4[nH]ccc4c3)nc2c1 +c1cnc2ccc(-c3cccc4oc5ccccc5c34)nc2c1 +c1cnc2ccc(-c3cccc4ocnc34)nc2c1 +c1cnc2ccc(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)nc2c1 +c1cnc2ccc(-c3ccnnc3)nc2c1 +c1cnc2ccc(-c3cncc4c3[nH]c3ccncc34)nc2c1 +c1cnc2ccc(-c3coc4nc5[nH]ccc5nc34)nc2c1 +c1cnc2ccc(-c3c[nH]c4cc5occc5cc34)nc2c1 +c1cnc2ccc(-c3nc4ccccc4s3)nc2c1 +c1cnc2ccc(-n3c4ccccc4c4cnccc43)nc2c1 +c1cnc2nc(-c3c4cc[nH]c4cc4occc34)cnc2n1 +c1cnc2nc(-c3cc4cc5ccoc5cc4[nH]3)cnc2n1 +c1cnc2nc(-c3cc4nc5ccoc5nc4[nH]3)cnc2n1 +c1cnc2nc(-c3ccc4c(n3)sc3ncccc34)ccc2c1 +c1cnc2nc(-c3ccc4ncc5ccccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4ncsc4c3)cnc2n1 +c1cnc2nc(-c3ccc4oc5ccccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4oc5ncccc5c4c3)ccc2c1 +c1cnc2nc(-c3ccc4[nH]ccc4c3)ccc2c1 +c1cnc2nc(-c3cccc4c3oc3ncccc34)ccc2c1 +c1cnc2nc(-c3cccc4c3sc3ncccc34)ccc2c1 +c1cnc2nc(-c3cccc4c5ccccc5c5[nH]cnc5c34)ccc2c1 +c1cnc2nc(-c3cccc4cnc5ccccc5c34)ccc2c1 +c1cnc2nc(-c3cccc4oc5ncccc5c34)ccc2c1 +c1cnc2nc(-c3cccc4ocnc34)ccc2c1 +c1cnc2nc(-c3cc[nH]n3)cnc2n1 +c1cnc2nc(-c3cncc4[nH]c5ccccc5c34)ccc2c1 +c1cnc2nc(-c3c[nH]c4nc5occc5nc34)cnc2n1 +c1cnc2nc(-n3c4ccccc4c4c5ccccc5[nH]c43)ccc2c1 +c1cnc2nc(-n3c4ccccc4c4ccncc43)ccc2c1 +c1cnc2ncc(-c3c4ccoc4cc4ccoc34)cc2c1 +c1cnc2ncc(-c3cc4nc5cc[nH]c5nc4o3)cc2c1 +c1cnc2ncc(-c3cc4[nH]c5ccccc5c4cn3)cc2c1 +c1cnc2ncc(-c3ccc4c(c3)[nH]c3cnccc34)cc2c1 +c1cnc2ncc(-c3ccc4c(n3)sc3ccccc34)cc2c1 +c1cnc2ncc(-c3ccc4[nH]c5ccncc5c4c3)cc2c1 +c1cnc2ncc(-c3ccc4[nH]c5cnccc5c4c3)cc2c1 +c1cnc2ncc(-c3cccc4c3cnc3ccccc34)cc2c1 +c1cnc2ncc(-c3cccc4c3[nH]c3cnccc34)cc2c1 +c1cnc2ncc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)cc2c1 +c1cnc2ncc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cc2c1 +c1cnc2ncc(-c3cccc4scnc34)cc2c1 +c1cnc2ncc(-c3cc[nH]n3)cc2c1 +c1cnc2ncc(-c3cncc4c3[nH]c3ccccc34)cc2c1 +c1cnc2ncc(-c3coc4nc5[nH]ccc5nc34)cc2c1 +c1cnc2ncc(-c3nc4ccccc4s3)cc2c1 +c1cnc2ncc(-c3nccc4[nH]c5ccccc5c34)cc2c1 +c1cnc2ncc(-n3cnc4c5ccccc5c5ccccc5c43)cc2c1 +c1cnc2nccc(-c3cc4[nH]c5ccncc5c4cn3)c2c1 +c1cnc2nccc(-c3ccc(-c4cc5c6c(c4)CCCN6CCC5)cc3)c2c1 +c1cnc2nccc(-c3ccc4c5ccccc5c5nccnc5c4c3)c2c1 +c1cnc2nccc(-c3ccc4ccsc4c3)c2c1 +c1cnc2nccc(-c3ccc4occc4c3)c2c1 +c1cnc2nccc(-c3ccc4sc5ncccc5c4c3)c2c1 +c1cnc2nccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)c2c1 +c1cnc2nccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c2c1 +c1cnc2nccc(-n3c4ccccc4c4ccncc43)c2c1 +c1cnc2nccc(-n3ccc4cc5ccoc5cc43)c2c1 +c1cnc2nccc(-n3cnc4c5ccccc5c5ccccc5c43)c2c1 +c1cnc2oc3c(-c4c5[nH]cnc5cc5nc[nH]c45)cccc3c2c1 +c1cnc2oc3c(-c4ccc5ncoc5c4)cccc3c2c1 +c1cnc2oc3c(-c4cnc5nccnc5n4)cccc3c2c1 +c1cnc2oc3c(-c4cncc5c4[nH]c4ccncc45)cccc3c2c1 +c1cnc2oc3c(-c4ncon4)cccc3c2c1 +c1cnc2oc3cc(-c4c5[nH]cnc5cc5nc[nH]c45)ccc3c2c1 +c1cnc2oc3cc(-c4cc5nc6cc[nH]c6nc5o4)ccc3c2c1 +c1cnc2oc3cc(-c4ccc5ncoc5c4)ccc3c2c1 +c1cnc2oc3cc(-c4cccc5c4[nH]c4cnccc45)ccc3c2c1 +c1cnc2oc3cc(-c4c[nH]c5ccncc45)ccc3c2c1 +c1cnc2oc3cc(-n4cnc5cc6nc[nH]c6cc54)ccc3c2c1 +c1cnc2oc3ccc(-c4c5[nH]cnc5nc5nc[nH]c45)cc3c2c1 +c1cnc2oc3ccc(-c4cc5cnccc5[nH]4)cc3c2c1 +c1cnc2oc3ccc(-c4cc5nc6cc[nH]c6nc5o4)cc3c2c1 +c1cnc2oc3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c2c1 +c1cnc2oc3ccc(-c4ccc5c(c4)[nH]c4cnccc45)cc3c2c1 +c1cnc2oc3ccc(-c4ccc5sccc5c4)cc3c2c1 +c1cnc2oc3ccc(-c4c[nH]c5ccncc45)cc3c2c1 +c1cnc2oc3ccc(-c4nc5cc6nc[nH]c6cc5[nH]4)cc3c2c1 +c1cnc2sc3c(-c4c5[nH]cnc5nc5nc[nH]c45)cccc3c2c1 +c1cnc2sc3c(-c4cncs4)cccc3c2c1 +c1cnc2sc3c(-c4nc5cc6nc[nH]c6cc5[nH]4)cccc3c2c1 +c1cnc2sc3c(-c4nc5nc6ocnc6nc5o4)cccc3c2c1 +c1cnc2sc3c(-c4nccs4)cccc3c2c1 +c1cnc2sc3c(-c4ncon4)cccc3c2c1 +c1cnc2sc3c(-n4cnc5nc6nc[nH]c6cc54)cccc3c2c1 +c1cnc2sc3cc(-c4c5nc[nH]c5cc5[nH]cnc45)ccc3c2c1 +c1cnc2sc3cc(-c4cc5cnccc5[nH]4)ccc3c2c1 +c1cnc2sc3cc(-c4coc5cc6ccoc6cc45)ccc3c2c1 +c1cnc2sc3cc(-c4c[nH]c5nc6occc6nc45)ccc3c2c1 +c1cnc2sc3cc(-c4ncno4)ccc3c2c1 +c1cnc2sc3cc(-n4c5ccccc5c5ccncc54)ccc3c2c1 +c1cnc2sc3ccc(-c4c5nc[nH]c5cc5[nH]cnc45)cc3c2c1 +c1cnc2sc3ccc(-c4cc5[nH]c6ccncc6c5cn4)cc3c2c1 +c1cnc2sc3ccc(-c4ccc(-c5cnccn5)cc4)cc3c2c1 +c1cnc2sc3ccc(-c4nc5nc6ocnc6nc5o4)cc3c2c1 +c1cnc2sc3ccc(-c4nccc5[nH]c6ccncc6c45)cc3c2c1 +c1cnc2sc3ccc(-n4cnc5nc6nc[nH]c6cc54)cc3c2c1 +c1cnc2sc3nc(-c4c5[nH]cnc5nc5nc[nH]c45)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5nn[nH]c5c4)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5ocnc5c4)ccc3c2c1 +c1cnc2sc3nc(-c4ccc5[nH]nnc5c4)ccc3c2c1 +c1cnc2sc3nc(-c4cnoc4)ccc3c2c1 +c1cnc2sc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)ccc3c2c1 +c1cnc2sc3nc(-c4nccc5[nH]ccc45)ccc3c2c1 +c1cnc2sc3ncc(-c4cc5nc6ccoc6nc5[nH]4)cc3c2c1 +c1cnc2sc3ncc(-c4cscn4)cc3c2c1 +c1cnc2sc3ncc(-c4c[nH]c5nc6occc6nc45)cc3c2c1 +c1cnc2sc3ncc(-n4c5ccccc5c5ccncc54)cc3c2c1 +c1cnc2sc3ncc(-n4c5ccncc5c5cnccc54)cc3c2c1 +c1cnc2sc3ncc(-n4cnc5nc6nc[nH]c6nc54)cc3c2c1 +c1cnc2sc3nccc(-c4cc5cnccc5[nH]4)c3c2c1 +c1cnc2sc3nccc(-c4ccc5ncoc5c4)c3c2c1 +c1cnc2sc3nccc(-c4ccc5ocnc5c4)c3c2c1 +c1cnc2sc3nccc(-c4ccon4)c3c2c1 +c1cnc2sc3nccc(-c4cnc5nccnc5n4)c3c2c1 +c1cnc2sc3nccc(-c4nc5nc6nc[nH]c6cc5[nH]4)c3c2c1 +c1cnc2sc3nccc(-n4c5ccccc5c5ccncc54)c3c2c1 +c1cnc2[nH]c3c(-c4c5cc[nH]c5cc5occc45)cccc3c2c1 +c1cnc2[nH]c3c(-c4cc5cc6ccoc6cc5[nH]4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5c(c4)c4ccccc4c4nccnc54)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5c6ccccc6c6nccnc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5oc6ncccc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4ccc5[nH]c6ccncc6c5c4)cccc3c2c1 +c1cnc2[nH]c3c(-c4c[nH]c5nc6occc6nc45)cccc3c2c1 +c1cnc2[nH]c3c(-c4nc5cc6ocnc6cc5o4)cccc3c2c1 +c1cnc2[nH]c3c(-c4nc5nc6nc[nH]c6nc5[nH]4)cccc3c2c1 +c1cnc2[nH]c3c(-c4nccc5[nH]c6ccncc6c45)cccc3c2c1 +c1cnc2[nH]c3cc(-c4c5ncoc5cc5ncoc45)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5c(n4)sc4ncccc45)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5c6ccccc6c6nc[nH]c6c5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5occc5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4ccc5[nH]c6ccncc6c5c4)ccc3c2c1 +c1cnc2[nH]c3cc(-c4nc5c6ccccc6c6ccccc6c5[nH]4)ccc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5c(c4)oc4ncccc45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5c6ccccc6c6nccnc6c5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5ccoc5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccc5oc6ncccc6c5c4)cc3c2c1 +c1cnc2[nH]c3ccc(-c4cccc5c6ccccc6c6[nH]cnc6c45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccnc5sc6ncccc6c45)cc3c2c1 +c1cnc2[nH]c3ccc(-c4ccnnc4)cc3c2c1 +c1cnc2[nH]c3ccc(-n4c5ccccc5c5cnccc54)cc3c2c1 +c1cnc2[nH]c3ccc(-n4cnc5nc6nc[nH]c6nc54)cc3c2c1 +c1cnn(-c2ccc(-c3cnccn3)cc2)c1 +c1cnn(-c2ccc3[nH]nnc3c2)c1 +c1cnn(-c2cscn2)c1 +c1cnn(-c2c[nH]c3nc4occc4nc23)c1 +c1cnn(-n2cnc3nc4nc[nH]c4nc32)c1 +c1cnnc(-c2cc3cccnc3c3ncccc23)c1 +c1cnnc(-c2ccc(-c3cnccn3)cc2)c1 +c1cnnc(-c2ccc3c(c2)[nH]c2ncccc23)c1 +c1cnnc(-c2ccc3c(cnc4ccccc43)c2)c1 +c1cnnc(-c2ccc3sc4ccccc4c3c2)c1 +c1cnnc(-c2ccc3[nH]c4cnccc4c3c2)c1 +c1cnnc(-c2cccc3cnc4ccccc4c23)c1 +c1cnnc(-c2ccnc3c2ccc2cccnc23)c1 +c1cnnc(-c2ccnc3cccnc23)c1 +c1cnnc(-c2cnc3[nH]c4ccccc4c3c2)c1 +c1cnnc(-c2cncc3cc[nH]c23)c1 +c1cnnc(-c2cnoc2)c1 +c1cnnc(-c2cscn2)c1 +c1cnnc(-c2nccs2)c1 +c1cnnc(-n2nnc3ccccc32)c1 +c1csc(-c2c3ncsc3cc3ncsc23)n1 +c1csc(-c2cc3nc4ccoc4nc3[nH]2)n1 +c1csc(-c2ccc3ccsc3c2)n1 +c1csc(-c2cn[nH]c2)n1 +c1csc(-c2coc3cc4[nH]ccc4cc23)n1 +c1csc(-c2c[nH]c3nc4occc4nc23)n1 +c1nc(-c2ccc3sccc3c2)cs1 +c1nc(-n2ccc3nc4ccoc4nc32)no1 +c1nc2c(-c3c4ncsc4cc4ncsc34)c3nc[nH]c3cc2[nH]1 +c1nc2c(-c3ccc4c5c3CCCN5CCC4)c3nc[nH]c3cc2[nH]1 +c1nc2c(-c3ccc4ncsc4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4nn[nH]c4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4scnc4c3)c3ncoc3nc2o1 +c1nc2c(-c3ccc4[nH]nnc4c3)c3scnc3cc2s1 +c1nc2c(-c3nc4nc5nc[nH]c5nc4[nH]3)c3nc[nH]c3cc2[nH]1 +c1nc2c(-n3ccc4nc5ccoc5nc43)c3nc[nH]c3cc2[nH]1 +c1nc2cc(-c3ccc4ncsc4c3)ccc2o1 +c1nc2cc(-c3ccc4nn[nH]c4c3)ccc2o1 +c1nc2cc(-c3ccc4ocnc4c3)ccc2o1 +c1nc2cc(-c3cnoc3)ccc2s1 +c1nc2cc(-c3cscn3)ccc2o1 +c1nc2cc3nc(-c4cc5nc6ccoc6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2cc3nc(-c4ccc5ccsc5c4)[nH]c3cc2[nH]1 +c1nc2cc3nc(-c4ccc5scnc5c4)oc3nc2o1 +c1nc2cc3nc(-c4ccc5[nH]nnc5c4)oc3nc2o1 +c1nc2cc3nc(-c4c[nH]c5nc6occc6nc45)[nH]c3cc2[nH]1 +c1nc2cc3ncn(-c4c5cc[nH]c5cc5occc45)c3cc2[nH]1 +c1nc2cc3ncn(-c4cc5c6c(c4)CCCN6CCC5)c3cc2[nH]1 +c1nc2cc3ncn(-c4ccc5ccsc5c4)c3cc2[nH]1 +c1nc2cc3ncn(-c4ccc5scnc5c4)c3cc2[nH]1 +c1nc2cc3oc(-c4ccc5nn[nH]c5c4)nc3cc2o1 +c1nc2cc3oc(-c4cnoc4)nc3cc2o1 +c1nc2ccc(-c3c4ncoc4nc4ocnc34)cc2o1 +c1nc2ccc(-c3c4ncsc4cc4ncsc34)cc2o1 +c1nc2ccc(-c3cnoc3)cc2o1 +c1nc2ccc(-c3c[nH]c4nc5occc5nc34)cc2o1 +c1nc2ccc(-c3nc4nc5ocnc5nc4o3)cc2o1 +c1nc2nc3nc(-c4c5ncsc5cc5ncsc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4c5[nH]ccc5cc5ccoc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4cc5nc6ccoc6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4ccc5scnc5c4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4c[nH]c5nc6occc6nc45)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5cc6ncoc6nc5o4)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)[nH]c3cc2[nH]1 +c1nc2nc3nc(-c4nc5nc6nc[nH]c6nc5[nH]4)[nH]c3nc2[nH]1 +c1nc2nc3nc(-c4nc5nc6ocnc6nc5o4)[nH]c3nc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]ccc5cc5ccoc45)c3cc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]ccc5cc5ccoc45)c3nc2[nH]1 +c1nc2nc3ncn(-c4c5[nH]cnc5nc5nc[nH]c45)c3nc2[nH]1 +c1nc2nc3ncn(-c4cc5nc6ccoc6nc5[nH]4)c3cc2[nH]1 +c1nc2nc3ncn(-c4ccc(-c5cc6c7c(c5)CCCN7CCC6)cc4)c3nc2[nH]1 +c1nc2nc3ncn(-c4ccc5ncoc5c4)c3nc2[nH]1 +c1nc2nc3ncn(-c4ncon4)c3nc2[nH]1 +c1nc2nc3nc[nH]c3c(-c3c4ncoc4cc4ncoc34)c2[nH]1 +c1nc2nc3nc[nH]c3c(-c3ccc4ocnc4c3)c2[nH]1 +c1nc2nc3nc[nH]c3c(-c3c[nH]c4cc5occc5cc34)c2[nH]1 +c1nc2nc3oc(-c4c5ncsc5cc5ncsc45)nc3nc2o1 +c1nc2nc3oc(-c4ccc(-c5cc6c7c(c5)CCCN7CCC6)cc4)nc3nc2o1 +c1nc2nc3oc(-c4ccc5scnc5c4)nc3nc2o1 +c1ncc(-c2ccc3[nH]nnc3c2)s1 +c1noc(-c2c3ncsc3cc3ncsc23)n1 +c1noc(-c2cc3c4c(c2)CCCN4CCC3)n1 +c1noc(-c2ccc3ocnc3c2)n1 +c1noc(-c2coc3cc4ccoc4cc23)n1 +c1noc(-c2nc3cc4ocnc4cc3o2)n1 +c1noc(-c2nc3nc4nc[nH]c4nc3[nH]2)n1 +c1nocc1-c1ccc2c3c1CCCN3CCC2 +CC(=O)c1ccc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +CC(=O)c1ccc(-c2cc(C)c3[nH]c4c(C)cccc4c3c2)cc1 +CC(=O)c1ccc(-c2cc(N(C)C)c3ccccc3c2)cc1 +CC(=O)c1ccc(-c2cc3c4c(c2)CCCN4CCC3)cc1 +CC(=O)c1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)cc1 +CC(=O)c1ccc(-c2cc3cc4cc[nH]c4cc3o2)cc1 +CC(=O)c1ccc(-c2cc3ccccc3[nH]2)cc1 +CC(=O)c1ccc(cc1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +CC(=O)c1ccc(cc1)c1cc2c(Sc3c(cccc3)N2)cc1 +CC(=O)c1ccc(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +CC(=O)c1ccc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)Oc2ccccc2N3C)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cc1 +CC(=O)c1ccc(-c2ccc3c(n2)sc2ccccc23)cc1 +CC(=O)c1ccc(-c2ccc3c4c(C)c(C)c(C)cc4n(C)c3c2)cc1 +CC(=O)c1ccc(-c2ccc3oc4ncccc4c3c2)cc1 +CC(=O)c1ccc(-c2ccc3[nH]c4ccc5c6ccccc6[nH]c5c4c3c2)cc1 +CC(=O)c1ccc(-c2cccc(N)c2)cc1 +CC(=O)c1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)cc1 +CC(=O)c1ccc(-c2cccc3c2-c2ccccc2C3(C)C)cc1 +CC(=O)c1ccc(cc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +CC(=O)c1ccc(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +CC(=O)c1ccc(-c2cccc3c2ncc2ccccc23)cc1 +CC(=O)c1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +CC(=O)c1ccc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +CC(=O)c1ccc(-c2cccc3oc4ccccc4c23)cc1 +CC(=O)c1ccc(-c2cccc3oc4ncccc4c23)cc1 +CC(=O)c1ccc(-c2cccc3occc23)cc1 +CC(=O)c1ccc(-c2cccc3scnc23)cc1 +CC(=O)c1ccc(-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)cc1 +CC(=O)c1ccc(-c2cccc3[nH]c4ccncc4c23)cc1 +CC(=O)c1ccc(-c2cc[nH]n2)cc1 +CC(=O)c1ccc(-c2coc3nc4[nH]ccc4nc23)cc1 +CC(=O)c1ccc(-c2nc3cc4scnc4cc3s2)cc1 +CC(=O)c1ccc(-c2nc3ccccc3o2)cc1 +CC(=O)c1ccc(-c2nccc3c2[nH]c2ccccc23)cc1 +CC(=O)c1ccc(-n2c3ccccc3c(=O)c3ccccc32)cc1 +CC(=O)c1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)cc1 +CC(=O)c1ccc(-n2c3ccccc3c3ccncc32)cc1 +CC(=O)c1ccc(-n2cnc3c4ccccc4c4ccccc4c32)cc1 +CC(=O)c1ccc(-n2nnc3ccccc32)cc1 +CC(=O)c1cccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +CC(=O)c1cccc(-c2c(C)c(C)c(C)c3c4ccccc4n(C)c23)c1 +CC(=O)c1cccc(c1)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +CC(=O)c1cccc(c1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +CC(=O)c1cccc(-c2cc3ccccc3cc2N(C)C)c1 +CC(=O)c1cccc(-c2cc3ccccc3o2)c1 +CC(=O)c1cccc(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +CC(=O)c1cccc(c1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +CC(=O)c1cccc(-c2ccc3c(n2)sc2ccccc23)c1 +CC(=O)c1cccc(c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +CC(=O)c1cccc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)c1 +CC(=O)c1cccc(-c2ccc3cc(N(C)C)ccc3c2)c1 +CC(=O)c1cccc(-c2ccc3occc3c2)c1 +CC(=O)c1cccc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c1 +CC(=O)c1cccc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c1 +CC(=O)c1cccc(c1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +CC(=O)c1cccc(c1)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +CC(=O)c1cccc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +CC(=O)c1cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +CC(=O)c1cccc(-c2cccc3c2oc2ncccc23)c1 +CC(=O)c1cccc(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)c1 +CC(=O)c1cccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c1 +CC(=O)c1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +CC(=O)c1cccc(-c2cccc3ocnc23)c1 +CC(=O)c1cccc(-c2cccc3scnc23)c1 +CC(=O)c1cccc(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c1 +CC(=O)c1cccc(-c2ccnc3sc4ncccc4c23)c1 +CC(=O)c1cccc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +CC(=O)c1cccc(-c2coc3cc4ccoc4cc23)c1 +CC(=O)c1cccc(-c2c[nH]c3ccccc23)c1 +CC(=O)c1ccccc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +CC(=O)c1ccccc1-c1c2ncsc2cc2ncsc12 +CC(=O)c1ccccc1-c1cc(C)c2[nH]c3c(C)cccc3c2c1 +CC(=O)c1ccccc1-c1cc2cc3cc[nH]c3cc2o1 +CC(=O)c1ccccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +CC(=O)c1ccccc1c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +CC(=O)c1ccccc1c1ccc2CCc3c(cccc3)Nc2c1 +CC(=O)c1ccccc1-c1ccc2c(c1)c1ccccc1c1nc[nH]c21 +CC(=O)c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12 +CC(=O)c1ccccc1-c1ccc2cc(N(C)C)ccc2c1 +CC(=O)c1ccccc1-c1ccc2oc3ccccc3c2c1 +CC(=O)c1ccccc1-c1ccc2oc3ncccc3c2c1 +CC(=O)c1ccccc1-c1ccc2[nH]c3ccccc3c(=O)c2c1 +CC(=O)c1ccccc1-c1ccc2[nH]c3cnccc3c2c1 +CC(=O)c1ccccc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +CC(=O)c1ccccc1-c1cccc2c1oc1ncccc12 +CC(=O)c1ccccc1-c1cccc2c1sc1ncccc12 +CC(=O)c1ccccc1-c1cccc2c3c(C)c(C)c(C)cc3n(C)c12 +CC(=O)c1ccccc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +CC(=O)c1ccccc1-c1cccc2cc(N(C)C)ccc12 +CC(=O)c1ccccc1-c1cccc2oc3ncccc3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3ccc4c5ccccc5[nH]c4c3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3cnccc3c12 +CC(=O)c1ccccc1-c1cccc2[nH]c3[nH]c4ccccc4c3c12 +CC(=O)c1ccccc1-c1cccnn1 +CC(=O)c1ccccc1-c1cncc2c1[nH]c1ccccc12 +CC(=O)c1ccccc1-c1cncc2c1[nH]c1ccncc12 +CC(=O)c1ccccc1-n1c2ccccc2c2ccncc21 +CC(=O)c1ccccc1-n1c2ccccc2c2cnccc21 +CC(=O)c1ccccc1-n1nnc2ccccc21 +Cc1(-c2c3ccoc3cc3ccoc23)-c2ccccc2-c2ccccc2-1 +N#Cc1c(c(C#N)cc(c1)C1(C)c2c(cccc2)Nc2c1cccc2)C#N +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2C2(C)c3c(cccc3)Nc3c2cccc3)ccccc1 +c12c(sc(c1)C1(C)c3c(cccc3)Nc3c1cccc3)cccc2 +Cc1(-c2cc3ccccc3[nH]2)-c2ccccc2-c2ccccc2-1 +N#Cc1ccc(c(C#N)c1)C1(C)c2c(cccc2)Nc2c1cccc2 +O=c1c2c(cc(cc2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +CC1(c2c(-c3c1cccc3)cccc2)c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1c2c(C(=O)N1)ccc(c2)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2ccc3c4c2CCCN4CCC3)-c2ccccc2-c2ccccc2-1 +c12c(b3c4c(oc5c3c(o1)c(cc5)C1(C)c3c(cccc3)Nc3c1cccc3)cccc4)cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)C1(C)c2c(cccc2)Nc2c1cccc2 +c12c(nn[nH]2)ccc(c1)C1(C)c2c(cccc2)Nc2c1cccc2 +n1c2c(oc1)ccc(c2)C1(C)c2c(cccc2)Nc2c1cccc2 +O=c1c2c(ccc(c2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +Cc1(-c2ccc3[nH]ccc(=O)c3c2)-c2ccccc2-c2ccccc2-1 +c12c(nn[nH]2)cc(cc1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c(=O)c4ccccc4[nH]c23)-c2ccccc2-c2ccccc2-1 +O=C1c2c(C(=O)N1)cccc2C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cccc3c2sc2ncccc23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c2[nH]c2ccc4c5ccccc5[nH]c4c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3c2[nH]c2cnccc23)-c2ccccc2-c2ccccc2-1 +c12c(c(ccc2)C2(C)c3c(cccc3)Nc3c2cccc3)[nH]c2ncccc12 +Cc1(-c2cccc3c4ccccc4c4nc[nH]c4c23)-c2ccccc2-c2ccccc2-1 +c12c(scc1)c(ccc2)C1(C)c2c(cccc2)Nc2c1cccc2 +c12c(cccc2C2(C)c3c(cccc3)Nc3c2cccc3)cnc2c1cccc2 +Cc1(-c2cccc3nn[nH]c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3oc4ncccc4c23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccc3occc23)-c2ccccc2-c2ccccc2-1 +Cc1(-c2cccnn2)-c2ccccc2-c2ccccc2-1 +c1(c2ncc(nc2)C2(C)c3c(cccc3)Nc3c2cccc3)ccccc1 +n1c2c(ccc1)ccc1c2ncc(c1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2cnc3c4ccccc4c4ccccc4c3n2)-c2ccccc2-c2ccccc2-1 +c12c(c3c(c(cnc3)C3(C)c4c(cccc4)Nc4c3cccc4)[nH]2)cncc1 +Cc1(-c2c[nH]c3ccccc23)-c2ccccc2-c2ccccc2-1 +n1c2nc3nc(C4(C)c5c(cccc5)Nc5c4cccc5)[nH]c3nc2[nH]c1 +n1c2nc3oc(nc3nc2oc1)C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-c2nccc3c2[nH]c2ccccc23)-c2ccccc2-c2ccccc2-1 +c12c(ccnc2C2(C)c3c(cccc3)Nc3c2cccc3)[nH]cc1 +n1ccsc1C1(C)c2c(cccc2)Nc2c1cccc2 +Cc1(-n2c3ccccc3c3cnccc32)-c2ccccc2-c2ccccc2-1 +O=C1c2c(C(=O)C(=C1)c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +O=c1c2c(cc(cc2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +O=C1c2c(C(=O)C=C1)ccc(c2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2c1ccnc2 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2ncccc12 +c12c(cc(cc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +n1c2c(oc1)cc(cc2)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(ccc(c2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]c2c1ccnc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(sc3c1cccc3c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(oc1)c(ccc2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)cccc1c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(nn[nH]2)c(ccc1)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(c2ncccc2c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ncccc1 +n1c2c(nccc2)c(cc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(ncc(c2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccc1 +c12c(c(cnc2)c2cc3c(cc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +c12c(c(cnc2)c2cc3c(cc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]cc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1cc(sc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c(csc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=c1c2c(cccc2)[nH]cc1c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(ccnc2)[nH]cc1c1cc2c(cc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1cc2c(cc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(c3c(n1c1cc4c(cc1)Nc1c5c6c(n(c7ccccc7)c5ccc1C4(C)C)cccc6)ccnc3)cncc2 +O=C1C=CC(=O)N1c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +n1c2c(c(c3c(nc[nH]3)c2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c1 +O=c1c2c(cc(cc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)cccc2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(cc(cc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)cnc2c1cccc2 +c12c(scc1)cc(cc2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +O=c1c2c(ccc(c2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(c(ccc2)c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2ncccc12 +c12c(cccc2)cnc2c1c(ccc2)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(cccc2c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2c1ccnc2 +c12c(cccc2c2c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc2)[nH]c2ncccc12 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +n1occ(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +c12c(n(c3c1ccnc3)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)cccc2 +c12c(n(cc1)c1c3c(C(c4c(cc5c6c(n(c7ccccc7)c5c4)cccc6)N3)(C)C)ccc1)ccnc2 +n1c2nc3nc[nH]c3cc2n(c1)c1c2c(C(c3c(cc4c5c(n(c6ccccc6)c4c3)cccc5)N2)(C)C)ccc1 +O=C1C=C(C(=O)N1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ccccc1 +c1(c2ncc(cc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ncccc1 +c1(c2nccnc2)ccc(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(cc(cc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12nccnc1ccc(c2)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(c(ccc2)c2c3c(ccc2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +c12c(sc3c1c(ccc3)c1c3c(ccc1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +n1c2ncccc2c(cc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(ccc1)ccc1c2ncc(c1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2ncc(nc2ncc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c(csc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2c(nc3c(nc(o3)c3c4c(ccc3)Nc3c(C4(C)C)cc4n(c5ccccc5)c5c(c4c3)cccc5)c2)oc1 +c1(C#N)cnc(nc1)c1c2c(ccc1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1cccc(C#N)c1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(c(c3c(nc[nH]3)c2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)[nH]c1 +c12nc3c(oc(c3)c3ccc4c(c3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)nc1[nH]cc2 +N#Cc1c(c(C#N)c(cc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3)C#N +N#Cc1ccc(c(C#N)c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +c12c(cc(cc2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)cnc2c1cccc2 +c12c(cccc2)[nH]c2nc(ccc12)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2nc(ccc2ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(ccc(c2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)cnc2c1cccc2 +c12c(cccc2)cnc2c1cc(cc2)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)ccc(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(nn[nH]2)cc(cc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1c(C#N)c(ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +c12c(nn[nH]2)c(ccc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +N#Cc1ccccc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2ncccc2c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ncccc1 +c1(c2nccc(c2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(nccc2)c(cc1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2nc(cnc2)c2ccc3c(c2)Nc2c(C3(C)C)cc3n(c4ccccc4)c4c(c3c2)cccc4)ccccc1 +c12c(c(cnc2)c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +n1cc(sc1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1cc(sc1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +c12c(cccc2)c(nc2c1cccc2)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1c2nc3nc(c4ccc5c(c4)Nc4c6c7c(n(c8ccccc8)c6ccc4C5(C)C)cccc7)[nH]c3cc2[nH]c1 +n1c2nc3nc(c4ccc5c(c4)Nc4c(C5(C)C)cc5n(c6ccccc6)c6c(c5c4)cccc6)[nH]c3nc2[nH]c1 +c12c(ccnc2c2ccc3c(c2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +n1ccsc1c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +n1cnoc1c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(c1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(c1)Nc1c(C2(C)C)cc2n(c3ccccc3)c3c(c2c1)cccc3 +O=C1c2c(C(=O)C(=C1)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(nc3c(nco3)c2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)oc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +N#Cc1c(c(C#N)cc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4)C#N +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1c3c(ccc1)Nc1c5c6c(n(c7ccccc7)c5ccc1C3(C)C)cccc6)cccc4)cccc2 +c12c(cc(nc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +N#Cc1ccc(cc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cc(cc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]c2ncccc12 +n1c2c(nc(cc2)c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccc1 +O=C(c1cccc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(sc3c1cccc3c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +c12c(scc1)c(ccc2)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(nn[nH]2)cccc1c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +O=c1c2c(cccc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)[nH]cc1 +N#Cc1ccccc1c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12c(cccc2)[nH]c2nccc(c12)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1occ(c1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12nc3c(occ3c3c4c(ccc3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)nc1[nH]cc2 +c12c(scc1c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c(csc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c12nc3c(occ3)nc1[nH]cc2c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +n1c2c(nc3c(nc(o3)c3c4c(ccc3)Nc3c5c6c(n(c7ccccc7)c5ccc3C4(C)C)cccc6)c2)oc1 +n1c2c(cc3c(nc(c4c5c(ccc4)Nc4c6c7c(n(c8ccccc8)c6ccc4C5(C)C)cccc7)[nH]3)c2)[nH]c1 +c1(C#N)cnc(nc1)c1c2c(ccc1)Nc1c3c4c(n(c5ccccc5)c3ccc1C2(C)C)cccc4 +c1(c2nccnc2c2c3c(ccc2)Nc2c4c5c(n(c6ccccc6)c4ccc2C3(C)C)cccc5)ccccc1 +c12c(n(c3ncccc13)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)cc2)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ccccc1 +O=c1c2c(cccc2)[nH]c(c1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +N#Cc1c(c(C#N)c(cc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1)C#N +N#Cc1ccc(cc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(scc1)cc(cc2)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(nn[nH]2)ccc(c1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(sc3c1cc(cc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +O=c1c2c(ccc(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)[nH]cc1 +c12c(cccc2c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)cnc2c1cccc2 +c12c(nn[nH]2)cccc1c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(sc3c1c(ccc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +c1(c2nccnc2)ccccc1c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c1(c2nccc(c2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ncccc1 +c1(c2nc(cnc2)c2c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc2)ccccc1 +c12c(c3c(c(cnc3)c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)[nH]2)cncc1 +c12nc3c(occ3c3c4c(C(c5c(c6c7c(n(c8ccccc8)c6cc5)cccc7)N4)(C)C)ccc3)nc1[nH]cc2 +n1c2nc3oc(nc3nc2oc1)c1c2c(C(c3c(c4c5c(n(c6ccccc6)c4cc3)cccc5)N2)(C)C)ccc1 +c12c(n(cc1)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)ccnc2 +CC1(c2c(-c3c1cccc3)cccc2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +O=C1c2c(C(=O)C(=C1)N1c3c(C(c4c1cccc4)(C)C)cc1n(c4ccccc4)c4c(c1c3)cccc4)cccc2 +O=C1c2c(C(=O)C(=C1)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +O=C1c2c(C(=O)N1N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +O=C1C=CC(=O)N1N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +O=C1C=CC(=O)N1N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2c(nc3c(nco3)c2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)oc1 +n1c2c(cc3c(nc[nH]3)c2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)ccccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)N2c3c(C(C)(c4c2cccc4)C)cccc3)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)N1c3c(C(c5c1cccc5)(C)C)cc1n(c5ccccc5)c5c(c1c3)cccc5)cccc4)cccc2 +n1c2c(ccc1)cc(c1c2nccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2nccnc2)ccc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +N#Cc1c(C#N)cc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +N#Cc1c(c(C#N)c(cc1)N1c2c(C(C)(c3c1cccc3)C)cccc2)C#N +N#Cc1ccc(cc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +O=c1c2c(cc(cc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(cccc2)cnc2c1ccc(c2)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(cccc2)cnc2c1ccc(c2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +c12c(sc3c1ccc(c3)N1c3c(C(c4c1cccc4)(C)C)cc1n(c4ccccc4)c4c(c1c3)cccc4)cccc2 +c12c(sc3c1ccc(c3)N1c3c(C(C)(c4c1cccc4)C)cccc3)cccc2 +c12c(cc(cc2)N2c3c(C(C)(c4c2cccc4)C)cccc3)cnc2c1cccc2 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)N1c3c5c6c(n(c7ccccc7)c5ccc3C(c3c1cccc3)(C)C)cccc6)cccc4)cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cc(cc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cc(cc2)N1c2c(C(C)(c3c1cccc3)C)cccc2 +c12nccnc1ccc(c2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(nn[nH]2)ccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(sc3c1cc(cc3)N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +c12c(ccc(c2)N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2c1ccnc2 +c12c(ccc(c2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]c2ncccc12 +c1(c2ncccc2)nc(ccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2ncccc2)nc(ccc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +N#Cc1cccc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +O=c1c2c(c(ccc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(c(ccc2)N2c3c(C(C)(c4c2cccc4)C)cccc3)cnc2c1cccc2 +c12c(cccc2N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)cnc2c1cccc2 +c12nccnc1c(ccc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(scc1)cccc2N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c12c(cccc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2c1ccnc2 +c12c(cccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c2c1ccnc2 +c12c(cccc2N2c3c(C(c4c2cccc4)(C)C)cc2n(c4ccccc4)c4c(c2c3)cccc4)[nH]c2ncccc12 +c12c(cccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)[nH]c2ncccc12 +O=c1c2c(cccc2N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)[nH]cc1 +c12c(nn[nH]2)c(ccc1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2nccnc2)ccccc1N1c2c(C(C)(c3c1cccc3)C)cccc2 +N#Cc1ccccc1N1c2c(C(C)(c3c1cccc3)C)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +c1(c2ncccc2N2c3c(C(C)(c4c2cccc4)C)cccc3)ncccc1 +c1(c2nccc(c2)N2c3c(C(C)(c4c2cccc4)C)cccc3)ncccc1 +n1occc1N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +n1c2c(ccc1)ccc1c2ncc(c1)N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +n1c2c(ccc1)ccc1c2ncc(c1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2ncc(cc2ccc1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +n1c2ncc(nc2ncc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c1(c2nc(cnc2)N2c3c4c5c(n(c6ccccc6)c4ccc3C(c3c2cccc3)(C)C)cccc5)ccccc1 +n1c(csc1)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +c12c(cccc2)[nH]c2c1ccnc2N1c2c(C(c3c1cccc3)(C)C)cc1n(c3ccccc3)c3c(c1c2)cccc3 +n1cnoc1N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +O=c1c2c(n(cc1)N1c3c4c5c(n(c6ccccc6)c4ccc3C(c3c1cccc3)(C)C)cccc5)cccc2 +c12nc3c(occ3)nc1n(cc2)N1c2c3c4c(n(c5ccccc5)c3ccc2C(c2c1cccc2)(C)C)cccc4 +n1c2nc3nc[nH]c3nc2n(c1)N1c2c(C(C)(c3c1cccc3)C)cccc2 +Fc1c(c(c(c(F)c1c1c2c(C(C)(c3c(cccc3)N2)C)ccc1)F)F)F +n1c2c(nc3c(nco3)c2c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)oc1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c1 +N#Cc1cc(cc(C#N)c1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)c2 +c12c(ccnc2)[nH]c(c1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(c3c(cc(nc3)c3c4c(C(C)(c5c(cccc5)N4)C)ccc3)[nH]2)cncc1 +c1(c2ncc(cc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ncccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(cc(cc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c2ncccc12 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(C(C)(c5c(cccc5)N3)C)ccc1)cccc4)cccc2 +c12c(scc1)ccc(c2)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(ccc(c2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)[nH]c2ncccc12 +c12c(sc3c1c(ccc3)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +n1c2c(nccc2)c(cc1)c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c1(c2ncc(nc2)c2c3c(C(C)(c4c(cccc4)N3)C)ccc2)ccccc1 +n1ccsc1c1c2c(C(C)(c3c(cccc3)N2)C)ccc1 +c12c(n(c3ncccc13)c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3c4c(c5c6c(n(c7ccccc7)c5c3)cccc6)Nc3c(C4(C)C)cccc3)cc2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)c2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +N#Cc1ccc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(cc(cc2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)cnc2c1cccc2 +n1c2c(nc(cc2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ccc1 +c12c(scc1)ccc(c2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(nn[nH]2)cc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)cccc2 +O=c1c2c(cccc2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)[nH]cc1 +c1(c2nccc(c2)c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ncccc1 +n1c2c(nccc2)c(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1oc(cc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12ncc(nc1cccc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c2ncc(cc2ccc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c(csc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +n1c2nc3oc(nc3nc2oc1)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +c1(c2nccnc2c2c3c(c4c5c(n(c6ccccc6)c4c2)cccc5)Nc2c(C3(C)C)cccc2)ccccc1 +n1ccsc1c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +O=c1c2c(n(cc1)c1c3c(c4c5c(n(c6ccccc6)c4c1)cccc5)Nc1c(C3(C)C)cccc1)cccc2 +c12nc3c(occ3)nc1n(cc2)c1c2c(c3c4c(n(c5ccccc5)c3c1)cccc4)Nc1c(C2(C)C)cccc1 +N#Cc1cc(C#N)cc(C#N)c1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3)F)F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)ccccc1 +c1(c2ncc(cc2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)ncccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3n(c5ccccc5)c5c(c3c3c(C(c6c(cccc6)N3)(C)C)c1)cccc5)cccc4)cccc2 +c12c(ccc(c2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)[nH]c2ncccc12 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3c3c(C(c5c(cccc5)N3)(C)C)c2)cccc4)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(nn[nH]2)cccc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +n1c2ncccc2c(cc1)c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +c12c(ccnc2)[nH]cc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +n1ccsc1c1c2n(c3ccccc3)c3c(c2c2c(C(c4c(cccc4)N2)(C)C)c1)cccc3 +CC1(c2c(-c3c1cccc3)cccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +O=C1c2c(C(=O)N1c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +O=c1c2c(cc(cc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)[nH]cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(c(ccc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)cnc2c1cccc2 +c12c(scc1)c(ccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(cccc2)cnc2c1c(ccc2)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +n1c2c(oc1)cccc2c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +c12c(sc3c1c(ccc3)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +c12c(nn[nH]2)c(ccc1)c1c2c3c(n(c4ccccc4)c2cc2c1Nc1c(C2(C)C)cccc1)cccc3 +n1c2c(ncc(c2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)ccc1 +c1(c2nc(cnc2)c2c3c4c(n(c5ccccc5)c3cc3c2Nc2c(C3(C)C)cccc2)cccc4)ccccc1 +c12c(occ1)cc1c(occ1c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)c2 +c12c(n(cc1)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)ccnc2 +CC1(c2c(-c3c1cccc3)cccc2)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +O=C1C=CC(=O)N1c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(cc3c(nc[nH]3)c2c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)[nH]c1 +N#Cc1c(c(C#N)c(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1)C#N +c12c(cccc2)cnc2c1ccc(c2)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(n(c5ccccc5)c5c3c3c(C(c6c(cccc6)N3)(C)C)cc5)ccc1)cccc4)cccc2 +n1c2c(nc(cc2)c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(oc1)cccc2c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(scc1)cccc2c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(nccc2)c(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1oc(cc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(ccc1)ccc1c2ncc(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1c2c(ncc(c2)c2c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc2)ccc1 +n1c2ncc(cc2ccc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +n1cc(sc1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(occ1)cc1c(occ1c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)c2 +n1c2c(nc3c(nc(o3)c3c4c(n(c5ccccc5)c5c4c4c(C(c6c(cccc6)N4)(C)C)cc5)ccc3)c2)oc1 +c12c(n(c3c1ccnc3)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +n1c2c(n(c1)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cc1c(nc[nH]1)c2 +n1c2nc3nc[nH]c3nc2n(c1)c1c2c(n(c3ccccc3)c3c2c2c(C(c4c(cccc4)N2)(C)C)cc3)ccc1 +c12c(nnn1c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +Fc1c(c(c(c(F)c1c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3)F)F)F +c12c(cccc2)[nH]c2c1cc(nc2)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(occ1)cc1c(oc(c1)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)c2 +c12nc3c(oc(c3)c3ccc4n(c5ccccc5)c5c(c4c3)c3c(C(c4c(cccc4)N3)(C)C)cc5)nc1[nH]cc2 +c12c(cc(nc2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +N#Cc1ccc(c(C#N)c1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(ccc(c2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)cnc2c1cccc2 +c1(c2ncccc2)nc(ccc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(c(ccc2)c2ccc3n(c4ccccc4)c4c(c3c2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]c2ncccc12 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1oc(cc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2ncc(nc2ncc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12nc3c(occ3)nc1[nH]cc2c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(cc3c(nc(c4ccc5n(c6ccccc6)c6c(c5c4)c4c(C(c5c(cccc5)N4)(C)C)cc6)[nH]3)c2)[nH]c1 +n1c2nc3oc(nc3nc2oc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(n(c3c1ccnc3)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2nc3nc[nH]c3nc2n(c1)c1ccc2n(c3ccccc3)c3c(c2c1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2ncc(cc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +N#Cc1ccc(c(C#N)c1)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +O=C1c2c(C(=O)C=C1)ccc(c2)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2c(nc(cc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccc1 +O=C1c2c(C(=O)N1)cccc2c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(scc1)cccc2c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2nccc(c2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2ncc(nc2)c2cc3n(c4ccccc4)c4c(c3cc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccccc1 +c12nc3c(occ3)nc1n(cc2)c1cc2n(c3ccccc3)c3c(c2cc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=C1c2c(C(=O)N1c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +N#Cc1cc(C#N)cc(C#N)c1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3)F)F)F +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)c(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ccccc1 +c12c(c3c(cc(nc3)c3c4n(c5ccccc5)c5c(c4ccc3)c3c(C(c4c(cccc4)N3)(C)C)cc5)[nH]2)cncc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(oc1)cc(cc2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +n1c2c(oc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(scc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +O=C(c1ccccc1c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3)C(F)(F)F +c1(c2nccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)c2c(C(c3c(cccc3)N2)(C)C)cc4)ncccc1 +n1c2c(nc3c(nc(o3)c3c4n(c5ccccc5)c5c(c4ccc3)c3c(C(c4c(cccc4)N3)(C)C)cc5)c2)oc1 +n1c2c(oc1c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c(noc1)c1c2n(c3ccccc3)c3c(c2ccc1)c1c(C(c2c(cccc2)N1)(C)C)cc3 +O=c1c2c(n(cc1)c1c3n(c4ccccc4)c4c(c3ccc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +N#Cc1c(c(C#N)cc(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1)C#N +c12c(b3c4c(oc5c3c(o1)cc(c5)c1ccc(n3c5c(c6c3ccc3c6Nc6c(C3(C)C)cccc6)cccc5)cc1)cccc4)cccc2 +c12nc3c(oc(c3)c3ccc(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cc3)nc1[nH]cc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1ccc(n3c5c(c6c3ccc3c6Nc6c(C3(C)C)cccc6)cccc5)cc1)cccc4)cccc2 +c12c(ccc(c2)c2ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc2)cnc2c1cccc2 +c1(c2nccnc2)cccc(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12-c3c(S(=O)(=O)c1cccc2)cccc3c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(c(ccc2)c2ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +N#Cc1ccccc1c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +n1occ(c1)c1ccc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(n(c3c1ccnc3)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +c12c(n(cc1)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)ccnc2 +N#Cc1cc(C#N)cc(C#N)c1c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1cc(cc(C#N)c1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cc(cc2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)cnc2c1cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(sc3c1cc(cc3)c1cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +N#Cc1c(C#N)c(ccc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(c(ccc2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)[nH]c2ncccc12 +n1c2c(oc1)c(ccc2)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nccc(c2)c2cc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)ccc2)ncccc1 +c12ncc(nc1cccc2)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2ncc(nc2ncc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(ccnc2)[nH]cc1c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1cc(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1cccc(C#N)c1c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +N#Cc1c(c(C#N)cc(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1)C#N +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3c(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cccc3)cc2)ccccc1 +c12c(c3c(cc(nc3)c3c(n4c5c(c6c4ccc4c6Nc6c(C4(C)C)cccc6)cccc5)cccc3)[nH]2)cncc1 +N#Cc1ccc(cc1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cc(cc2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)[nH]c2c1ccnc2 +O=C(c1cccc(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1)C(F)(F)F +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +c1(c2nccc(c2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)ncccc1 +c12ncc(nc1cccc2)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(c(cnc2)c2c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc2)[nH]cc1 +n1ccsc1c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(n(c3ncccc13)c1c(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +n1c2nc3nc[nH]c3nc2n(c1)c1c(n2c3c(c4c2ccc2c4Nc4c(C2(C)C)cccc4)cccc3)cccc1 +O=C1c2c(C(=O)N1c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)cc(cc4)c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1cc3c(C(C)(c5c(cccc5)N3)C)cc1)cccc4)cccc2 +n1c2c(oc1)cc(cc2)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c12c(ccc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]c2c1ccnc2 +O=c1c2c(ccc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c1(c2nccnc2)cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +N#Cc1cccc(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(c(ccc2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)[nH]cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +N#Cc1ccccc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +c1(c2ncccc2c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)ncccc1 +n1occc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +n1c2c(ncc(c2)c2cc3c(C(C)(c4c(cccc4)N3)C)cc2)ccc1 +n1occ(c1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +n1c(csc1)c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(cccc2)[nH]cc1c1cc2c(C(C)(c3c(cccc3)N2)C)cc1 +O=c1c2c(cccc2)[nH]c(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1c3c(n(c5ccccc5)c5c3cc3c(C(c6c(cccc6)N3)(C)C)c5)ccc1)cccc4)cccc2 +c12c(occ1)cc1c(oc(c1)c1c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc1)c2 +c12c(cc(nc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]cc1 +N#Cc1ccc(c(C#N)c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(cc(cc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)cnc2c1cccc2 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1c3c(n(c5ccccc5)c5c3cc3c(C(c6c(cccc6)N3)(C)C)c5)ccc1)cccc4)cccc2 +O=c1c2c(ccc(c2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]cc1 +c1(c2ncccc2)nc(ccc1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +N#Cc1cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c12c(c(ccc2)c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)[nH]c2c1ccnc2 +n1c2c(oc1)c(ccc2)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +c1(c2ncccc2c2c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc2)ncccc1 +c12c(cccc2)[nH]c2nccc(c12)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1occc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1occ(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +O=c1c2c(cccc2)[nH]cc1c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +n1c2nc3nc(c4c5c(n(c6ccccc6)c6c5cc5c(C(c7c(cccc7)N5)(C)C)c6)ccc4)[nH]c3cc2[nH]c1 +c12c(n(c3ncccc13)c1c3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)ccc1)cccc2 +n1c2nc3nc[nH]c3cc2n(c1)c1c2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)ccc1 +O=C1c2c(C(=O)C(=C1)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +O=C1c2c(C(=O)N1c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +O=C1C=CC(=O)N1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)cc2)ccccc1 +O=c1c2c(cccc2)[nH]c(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)[nH]c2c1cc(nc2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12nc3c(occ3)nc1[nH]c(c2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +N#Cc1c(C#N)cc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +N#Cc1ccc(cc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)[nH]c2nc(ccc12)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(nc(cc2)c2cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc2)ccc1 +c12c(nn[nH]2)ccc(c1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(cccc2)cnc2c1cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(nn[nH]2)cccc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(scc1)cccc2c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +O=C(c1ccccc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1)C(F)(F)F +c12ncc(nc1cccc2)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2ncc(cc2ccc1)c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12nc3c(occ3c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)nc1[nH]cc2 +O=c1c2c(cccc2)[nH]cc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +c12c(ccnc2)[nH]cc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(nc3c(nc(o3)c3cc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)cc3)c2)oc1 +n1ccsc1c1cc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)cc1 +n1c2c(n(c1)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cc1c(nc[nH]1)c2 +n1c2c(nc3c(nco3)c2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)oc1 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3ccc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)c3)cc2)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)ccccc1 +c12c(occ1)cc1c(oc(c1)c1ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c1)c2 +n1c2c(ccc1)cc(c1c2nccc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c1(c2nccnc2)cccc(c1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(c(ccc2)c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2ncccc12 +c12c(nn[nH]2)cccc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(cccc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2c1ccnc2 +c12c(cccc2c2ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c2)[nH]c2ncccc12 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(ccnc2)[nH]cc1c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +n1c2c(nc3c(nc(o3)c3ccc4c(n(c5ccccc5)c5c4cc4c(C(c6c(cccc6)N4)(C)C)c5)c3)c2)oc1 +n1c2nc3oc(nc3nc2oc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +n1c(noc1)c1ccc2c(n(c3ccccc3)c3c2cc2c(C(c4c(cccc4)N2)(C)C)c3)c1 +c12c(n(cc1)c1ccc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)c1)ccnc2 +Fc1c(c(c(c(F)c1c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3)F)F)F +N#Cc1c(c(C#N)cc(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3)C#N +c12c(ccnc2)[nH]c(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +c12c(c3c(cc(nc3)c3c4n(c5ccccc5)c5c(c4ccc3)cc3c(C(c4c(cccc4)N3)(C)C)c5)[nH]2)cncc1 +c12c(cccc2)[nH]c2nc(ccc12)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(oc1)cc(cc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +O=c1c2c(ccc(c2)c2c3n(c4ccccc4)c4c(c3ccc2)cc2c(C(c3c(cccc3)N2)(C)C)c4)[nH]cc1 +c12c(cccc2)cnc2c1c(ccc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(oc1)c(ccc2)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2ncccc2c(cc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2c(nc3c(nc(o3)c3c4n(c5ccccc5)c5c(c4ccc3)cc3c(C(c4c(cccc4)N3)(C)C)c5)c2)oc1 +c1(C#N)cnc(nc1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +n1c2nc3nc[nH]c3nc2n(c1)c1c2n(c3ccccc3)c3c(c2ccc1)cc1c(C(c2c(cccc2)N1)(C)C)c3 +N#Cc1cc(C#N)cc(C#N)c1c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +Fc1c(c(c(c(F)c1c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1)F)F)F +n1c2c(cc3c(nc[nH]3)c2c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c1 +n1c2c(c(c3c(nc[nH]3)c2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c1 +c12c(occ1)cc1c(oc(c1)c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)c2 +c12c(sc(c1)c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +O=c1c2c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]cc1 +c12c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +c12c(cc(cc2)c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)cnc2c1cccc2 +n1c2c(ccc1)ccc1c2nc(cc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)cnc2c1cc(cc2)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c1(c2ncccc2)nc(ccc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)cnc2c1cccc2c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(scc1)c(ccc2)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2c2ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc2)[nH]c2ncccc12 +n1c2c(nccc2)c(cc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c12c(occ1)cc1c(occ1c1ccc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cc1)c2 +c12c(c3c(ccnc3)[nH]2)c(ncc1)c1ccc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3c3cc(n4c5c(c6c4cc4c(c6)Nc6c(C4(C)C)cccc6)cccc5)ccc3)cc2)ccccc1 +n1c2c(ccc1)cc(c1c2nccc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +N#Cc1ccc(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(ccc(c2)c2cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc2)cnc2c1cccc2 +c1(c2ncccc2)nc(ccc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=C(c1cccc(c1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1)C(F)(F)F +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(b3c4c(oc5c3c(o1)ccc5)cccc4c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +n1c2c(ccc1)ccc1c2nccc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c2ncccc2c(cc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=c1c2c(cccc2)[nH]cc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c12c(cccc2)[nH]c2c1ccnc2c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +c1(C#N)cncnc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1cnoc1c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +n1c(noc1)c1cc(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)ccc1 +O=c1c2c(n(cc1)c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3n(c4ccccc4)c4c(c3cc3c1C(c1c(cccc1)N3)(C)C)cccc4)cccc2 +c12c(occ1)c(c1c(occ1)c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +O=c1c2c(cccc2)[nH]c(c1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +c12c(cc(nc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]cc1 +N#Cc1c(c(C#N)c(cc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3)C#N +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +O=C1c2c(C(=O)N1)ccc(c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2nc(ccc2ccc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(cccc2)cnc2c1cc(cc2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1c2c(oc1)ccc(c2)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(ccc(c2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]c2c1ccnc2 +O=C1c2c(C(=O)N1)cccc2c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +N#Cc1ccccc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(cccc2)[nH]c2nccc(c12)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(c2ncc(nc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +n1c2ncc(cc2ccc1)c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c1(c2nc(cnc2)c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)ccccc1 +O=c1c2c(cccc2)[nH]cc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(ccnc2c2c3n(c4ccccc4)c4c(c3cc3c2C(c2c(cccc2)N3)(C)C)cccc4)[nH]cc1 +n1ccsc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +n1cnoc1c1c2n(c3ccccc3)c3c(c2cc2c1C(c1c(cccc1)N2)(C)C)cccc3 +c12c(n(c3c1ccnc3)c1c3n(c4ccccc4)c4c(c3cc3c1C(c1c(cccc1)N3)(C)C)cccc4)cccc2 +O=C1c2c(C(=O)N1c1c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc1)cccc2 +c12c(occ1)c(c1c(occ1)c2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2c2c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc2)ccccc1 +c12nc3c(oc(c3)c3c(n4c5c(c6c4cc4c(c6)Nc6c(C4(C)C)cccc6)cccc5)cccc3)nc1[nH]cc2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +N#Cc1ccc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cccc2)cnc2c1c(ccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +O=C(c1ccccc1c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1)C(F)(F)F +n1c2ncccc2c(cc1)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12c(cccc2)[nH]c2nccc(c12)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +c12ncc(nc1cccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(ncc(c2)c2c(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)cccc2)ccc1 +c12c(cccc2)c(nc2c1cccc2)c1c(n2c3c(c4c2cc2c(c4)Nc4c(C2(C)C)cccc4)cccc3)cccc1 +n1c2c(nc3c(nco3)c2c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)oc1 +n1c2c(cc3c(nc[nH]3)c2c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)cc2)ccccc1 +c12c(sc(c1)c1ccc3c(C(C)(c4c(cccc4)N3)C)c1)cccc2 +c12nc3c(oc(c3)c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)nc1[nH]cc2 +N#Cc1c(C#N)cc(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +N#Cc1c(c(C#N)c(cc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1)C#N +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12c(b3c4c(oc5c3c(o1)c(cc5)c1ccc3c(C(C)(c5c(cccc5)N3)C)c1)cccc4)cccc2 +O=c1c2c(ccc(c2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]cc1 +c12c(c(ccc2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)[nH]c2ncccc12 +c12c(nn[nH]2)c(ccc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c12c(cccc2)[nH]c2nccc(c12)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +n1c2ncc(cc2ccc1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +c1(c2nc(cnc2)c2ccc3c(C(C)(c4c(cccc4)N3)C)c2)ccccc1 +c12nc3c(occ3c3ccc4c(C(C)(c5c(cccc5)N4)C)c3)nc1[nH]cc2 +n1c2nc3nc[nH]c3cc2n(c1)c1ccc2c(C(C)(c3c(cccc3)N2)C)c1 +O=C1C=C(C(=O)N1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2nc3nc[nH]c3c(c2[nH]c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(ccnc2)[nH]c(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nccnc2)ccc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +N#Cc1ccc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12-c3c(S(=O)(=O)c1cccc2)ccc(c3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2)cnc2c1ccc(c2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cc(cc2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2ncccc12 +n1c2c(oc1)ccc(c2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(ccc(c2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2ncccc12 +c1(c2ncccc2)nc(ccc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nccnc2)cccc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +O=c1c2c(c(ccc2)c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]cc1 +c12-c3c(S(=O)(=O)c1cccc2)c(ccc3)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(b3c4c(oc5c3c(o1)ccc5)c(ccc4)c1c3C(C)(c4c(cccc4)Nc3ccc1)C)cccc2 +c12c(scc1)c(ccc2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(oc1)c(ccc2)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(scc1)cccc2c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]c2c1ccnc2 +O=c1c2c(cccc2c2c3C(C)(c4c(cccc4)Nc3ccc2)C)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccccc1c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1oc(cc1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(ccc1)ccc1c2ncc(c1)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(cccc2)[nH]c2ncc(cc12)c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12nc3c(occ3)nc1[nH]cc2c1c2C(C)(c3c(cccc3)Nc2ccc1)C +n1c2c(cc3c(nc(c4c5C(C)(c6c(cccc6)Nc5ccc4)C)[nH]3)c2)[nH]c1 +n1ccsc1c1c2C(C)(c3c(cccc3)Nc2ccc1)C +c12c(c3c(n1c1c4C(C)(c5c(cccc5)Nc4ccc1)C)ccnc3)cncc2 +c12c(n(cc1)c1c3C(C)(c4c(cccc4)Nc3ccc1)C)ccnc2 +CC1(C)c2ccccc2-c2c(-c3cc(C#N)cc(C#N)c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cc4cccnc4c4ncccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4cccnc4n3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4cnc5ccccc5c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4[nH]c5ncccc5c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccc4[nH]ccc(=O)c4c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4c3cnc3ccccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4cnc5ccccc5c34)cccc21 +CC1(C)c2ccccc2-c2c(-c3cccc4[nH]c5ncccc5c34)cccc21 +CC1(C)c2ccccc2-c2c(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc21 +CC1(C)c2ccccc2-c2c(-c3csc4ccccc34)cccc21 +CC1(C)c2ccccc2-c2c(-c3nc4nc5nc[nH]c5cc4[nH]3)cccc21 +CC1(C)c2ccccc2-c2c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc21 +CC1(C)c2ccccc2-c2c(-n3ccc4nc5ccoc5nc43)cccc21 +CC1(C)c2ccccc2-c2c(-n3cnc4cc5nc[nH]c5cc43)cccc21 +CC1(C)c2ccccc2-c2c(-n3cnc4nc5nc[nH]c5nc43)cccc21 +CC1(C)c2ccccc2-c2cc(-c3c(C#N)cccc3C#N)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(=O)c4ccccc4[nH]3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc(C#N)c(C#N)c(C#N)c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc4cc5occc5cc4o3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cc4nc5cc[nH]c5nc4o3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc(-c4ccccn4)n3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc(C#N)c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3C(=O)c=cC4=O)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3cnc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3ncc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cccc4c3sc3ccccc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ccnc4[nH]c5ccccc5c34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3cnc4[nH]c5ccccc5c4c3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3coc4cc5ccoc5cc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3c[nH]c4nc5occc5nc34)ccc21 +CC1(C)c2ccccc2-c2cc(-c3nccnc3-c3ccccc3)ccc21 +CC1(C)c2ccccc2-c2cc(-c3ncno3)ccc21 +CC1(C)c2ccccc2-c2cc(-n3ccc4cnccc43)ccc21 +CC1(C)c2ccccc2-c2ccc(-c3cc4c(cn3)[nH]c3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cc4cc5occc5cc4o3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc(C#N)c(C#N)c3C#N)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)ncc3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4c(cnc5ccccc54)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccc4[nH]c5cnccc5c4c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc4c(=O)cc[nH]c34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc4c3cnc3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccno3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnc(-c4ccccc4)cn3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnc4c(ccc5cccnc54)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3cnoc3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nccc4c3[nH]c3ccccc34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3nccc4[nH]c5ccncc5c34)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ncon3)cc21 +CC1(C)c2ccccc2-c2ccc(-n3c4ccncc4c4cnccc43)cc21 +CC1(C)c2ccccc2-c2ccc(-n3nnc4ccccc43)cc21 +CC1(C)c2ccccc2-c2cccc(-c3c4nc[nH]c4cc4[nH]cnc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c21 +CC1(C)c2ccccc2-c2cccc(-c3cc4ccccc4s3)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc(C#N)c(C#N)c3C#N)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc4c(c3)ncc3ccccc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccc4c(c3)[nH]c3ncccc34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cccc(C(=O)C(F)(F)F)c3)c21 +O=C1c2c(C(=O)N1)cccc2c1c2C(C)(C)c3c(-c2ccc1)cccc3 +CC1(C)c2ccccc2-c2cccc(-c3cccc4sc5ccccc5c34)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccccc3C#N)c21 +CC1(C)c2ccccc2-c2cccc(-c3ccnc4[nH]c5ccccc5c34)c21 +CC1(C)c2ccccc2-c2cccc(-c3cscn3)c21 +CC1(C)c2ccccc2-c2cccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c21 +CC1(C)c2ccccc2-c2cccc(-c3nc4nc5nc[nH]c5cc4[nH]3)c21 +O=C1C=CC(=O)N1N1c2c([C@H](C)c3c1cccc3)cccc2 +N#Cc1cccc(C#N)c1N1c2c(C(C)c3c1cccc3)cccc2 +n1c2nc3nc[nH]c3c(c2[nH]c1)N1c2c(C(C)c3c1cccc3)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)N3c4c(C(C)c5c3cccc5)cccc4)cc2)ccccc1 +N#Cc1cc(cc(C#N)c1)N1c2c(C(C)c3c1cccc3)cccc2 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +c12c(cccc2)[nH]c2nc(ccc12)N1c2c(C(C)c3c1cccc3)cccc2 +c12c(sc3c1cc(cc3)N1c3c(C(C)c4c1cccc4)cccc3)cccc2 +O=c1c2c(ccc(c2)N2c3c(C(C)c4c2cccc4)cccc3)[nH]cc1 +N#Cc1cccc(c1)N1c2c(C(C)c3c1cccc3)cccc2 +c12-c3c(S(=O)(=O)c1cccc2)cccc3N1c2c(C(C)c3c1cccc3)cccc2 +O=C(c1ccccc1N1c2c(C(C)c3c1cccc3)cccc2)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1N1c2c(C(C)c3c1cccc3)cccc2 +n1oc(cc1)N1c2c(C(C)c3c1cccc3)cccc2 +n1c2c(ncc(c2)N2c3c(C(C)c4c2cccc4)cccc3)ccc1 +c12c(c3c(c(cnc3)N3c4c(C(C)c5c3cccc5)cccc4)[nH]2)cncc1 +c12nc3c(occ3N3c4c(C(C)c5c3cccc5)cccc4)nc1[nH]cc2 +c12c(c3c(n1N1c4c(C(C)c5c1cccc5)cccc4)ccnc3)cncc2 +n1c2nc3nc[nH]c3cc2n(c1)N1c2c(C(C)c3c1cccc3)cccc2 +N#Cc1cc(C#N)cc(C#N)c1c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)c3c4c([C@@H](C)c5c(cccc5)N4)ccc3)cc2)ccccc1 +N#Cc1c(c(C#N)c(cc1)c1c2c([C@H](C)c3c(cccc3)N2)ccc1)C#N +c12-c3c(S(=O)(=O)c1cccc2)cc(cc3)c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +n1c2c(oc1)cc(cc2)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +c12c(scc1)ccc(c2)c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +c12c(c(ccc2)c2c3c([C@@H](C)c4c(cccc4)N3)ccc2)[nH]c2ncccc12 +n1c2c(ccc1)ccc1c2nccc1c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +c12c(c(cnc2)c2c3c([C@H](C)c4c(cccc4)N3)ccc2)[nH]cc1 +c12c(cccc2)[nH]c2c1c(cnc2)c1c2c([C@@H](C)c3c(cccc3)N2)ccc1 +O=c1c2c(cccc2)[nH]cc1c1c2c([C@H](C)c3c(cccc3)N2)ccc1 +N#Cc1cc(C#N)cc(C#N)c1c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +n1c2nc3nc[nH]c3c(c2[nH]c1)c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2cc3c([C@H](C)c4c(cccc4)N3)cc2)ccccc1 +c12c(b3c4c(oc5c3c(o1)cc(c5)c1cc3c([C@H](C)c5c(cccc5)N3)cc1)cccc4)cccc2 +c12c(c3c(cc(nc3)c3cc4c([C@H](C)c5c(cccc5)N4)cc3)[nH]2)cncc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(b3c4c(oc5c3c(o1)ccc5)ccc(c4)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(sc3c1ccc(c3)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +n1c2nc(ccc2ccc1)c1cc2c([C@@H](C)c3c(cccc3)N2)cc1 +c12c(cccc2)cnc2c1cc(cc2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(sc3c1cc(cc3)c1cc3c([C@@H](C)c4c(cccc4)N3)cc1)cccc2 +O=c1c2c(ccc(c2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)[nH]cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)cccc(c1)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +O=C1c2c(C(=O)C=C1)cccc2c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +c12c(c(ccc2)c2cc3c([C@H](C)c4c(cccc4)N3)cc2)cnc2c1cccc2 +c12c(sc3c1c(ccc3)c1cc3c([C@H](C)c4c(cccc4)N3)cc1)cccc2 +c1(c2ncccc2c2cc3c([C@H](C)c4c(cccc4)N3)cc2)ncccc1 +n1c2c(ncc(c2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)ccc1 +c1(c2nc(cnc2)c2cc3c([C@@H](C)c4c(cccc4)N3)cc2)ccccc1 +n1c2nc3nc(c4cc5c([C@@H](C)c6c(cccc6)N5)cc4)[nH]c3cc2[nH]c1 +c12c(n(c3c1ccnc3)c1cc3c([C@H](C)c4c(cccc4)N3)cc1)cccc2 +c12nc3c(occ3)nc1n(cc2)c1cc2c([C@H](C)c3c(cccc3)N2)cc1 +O=C1C=C(C(=O)N1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +N#Cc1c(c(C#N)cc(c1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1)C#N +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)c(c2)c2ccc3c([C@@H](C)c4c(cccc4)N3)c2)ccccc1 +c12c(cc(nc2)c2ccc3c([C@H](C)c4c(cccc4)N3)c2)[nH]cc1 +N#Cc1c(c(C#N)c(cc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1)C#N +N#Cc1ccc(cc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=C(c1ccc(cc1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1)C(F)(F)F +c12c(ccc(c2)c2ccc3c([C@H](C)c4c(cccc4)N3)c2)cnc2c1cccc2 +c12c(nn[nH]2)ccc(c1)c1ccc2c([C@@H](C)c3c(cccc3)N2)c1 +c12nccnc1c(ccc2)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c2c(oc1)c(ccc2)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c2c(oc1)cccc2c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +N#Cc1ccccc1c1ccc2c([C@@H](C)c3c(cccc3)N2)c1 +O=C(c1ccccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1)C(F)(F)F +c1(c2ncccc2c2ccc3c([C@H](C)c4c(cccc4)N3)c2)ncccc1 +n1c2c(ccc1)ccc1c2nccc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=c1c2c(cccc2)[nH]cc1c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +n1c(noc1)c1ccc2c([C@H](C)c3c(cccc3)N2)c1 +O=c1c2c(n(cc1)c1ccc3c([C@@H](C)c4c(cccc4)N3)c1)cccc2 +n1c2c(cc3c(nc[nH]3)c2c2c3c(ccc2)Nc2c([C@@H]3C)cccc2)[nH]c1 +c12c(cccc2)[nH]c2c1cc(nc2)c1c2c(ccc1)Nc1c([C@@H]2C)cccc1 +n1c2c(ccc1)ccc1c2nc(cc1)c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +n1c2c(oc1)ccc(c2)c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +c1(c2ncccc2c2c3c(ccc2)Nc2c([C@@H]3C)cccc2)ncccc1 +c12c(cccc2)[nH]c2ncc(cc12)c1c2c(ccc1)Nc1c([C@@H]2C)cccc1 +n1c2c(cc3c(nc(c4c5c(ccc4)Nc4c([C@H]5C)cccc4)[nH]3)c2)[nH]c1 +n1ccsc1c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +n1cnoc1c1c2c(ccc1)Nc1c([C@H]2C)cccc1 +Cc1-c2ccccc2-c2c(-c3c4ncoc4cc4ncoc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cc4c(cn3)[nH]c3ccccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cccc2-1 +C[C@@H]1c2c(-c3c1cccc3c1ccc3c(c1)Nc1c(C3(C)C)cc3n(c4ccccc4)c4c(c3c1)cccc4)cccc2 +C[C@H]1c2c(-c3c1cccc3c1cc3c(C(C)(c4c(cccc4)N3)C)cc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +Cc1-c2ccccc2-c2c(-c3ccc4cc(N(C)C)ccc4c3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)cccc2-1 +C[C@H]1c2c(-c3c1cccc3c1cc(n3c4c(c5c3cc3c(c5)Nc5c(C3(C)C)cccc5)cccc4)ccc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +C[C@@H]1c2c(-c3c1cccc3c1c3c(C(C)(c4c(cccc4)N3)C)ccc1)cccc2 +C[C@H]1c2c(-c3c1cccc3c1c3c(CCc4c(cccc4)N3)ccc1)cccc2 +Cc1-c2ccccc2-c2c(-c3cccc4c3oc3ccccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4c3Oc3ccccc3O4)cccc2-1 +C[C@H]1c2c(-c3c1cccc3c1c3n(c4ccccc4)c4c(c3ccc1)cc1c(C(c3c(cccc3)N1)(C)C)c4)cccc2 +Cc1-c2ccccc2-c2c(-c3cccc4ncoc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4oc5ncccc5c34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4sccc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cccc4[nH]nnc34)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccccc3N(c3ccccc3)c3ccccc3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3ccccc3N)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cnc4sc5ncccc5c4c3)cccc2-1 +Cc1-c2ccccc2-c2c(-c3cncc4[nH]c5ccccc5c34)cccc2-1 +C[C@H]1c2c(-c3c1cccc3N1c3c(Sc4c1cccc4)cccc3)cccc2 +Cc1-c2ccccc2-c2c-1cccc2-n1nnc2ccccc21 +C[C@H]1c2c(-c3c1ccc(c3)N1c3c([C@@H](C)c4c1cccc4)cccc3)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)N1c3c(CCc4c1cccc4)cccc3)cccc2 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c4c(n(c5ccccc5)c3cc3c1Nc1c(C3(C)C)cccc1)cccc4)cccc2 +Cc1-c2ccccc2-c2cc(-c3c4ccoc4cc4ccoc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3c4ncoc4cc4ncoc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cc4cc5occc5cc4o3)ccc2-1 +C[C@H]1c2c(-c3c1ccc(c3)c1ccc(n3c4c(c5c3ccc3c5Nc5c(C3(C)C)cccc5)cccc4)cc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1ccc3n(c4ccccc4)c4c(c3c1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)Oc3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3cnccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4cnc5ccccc5c4c3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3ccc4oc5ncccc5c4c3)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c([C@H](C)c4c(cccc4)N3)ccc1)cccc2 +C[C@H]1c2c(-c3c1ccc(c3)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +Cc1-c2ccccc2-c2cc(-c3cccc4c3-c3ccccc3C4(C)C)ccc2-1 +C[C@@H]1c2c(-c3c1ccc(c3)c1c3c(ccc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +Cc1-c2ccccc2-c2cc(-c3cccc4c3cnc3ccccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3N(C)c3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3Oc3ccccc3N4C)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c3[nH]c3ccncc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4c5nc[nH]c5c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4cc(N(C)C)ccc34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4nn[nH]c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4oc5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3cn[nH]c3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3c[nH]c4ccccc4c3=O)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nc4cc5ocnc5cc4o3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nc4cc5scnc5cc4s3)ccc2-1 +Cc1-c2ccccc2-c2cc(-c3nccc4[nH]c5ccccc5c34)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccccc4c4ccncc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3c4ccncc4c4cnccc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3ccc4nc5ccoc5nc43)ccc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc(N(C)C)c4ccccc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4cc5occc5cc4o3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4ccccc4cc3N(C)C)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cc4ccccc4[nH]3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)N(C)c3ccccc3O4)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)sc3ncccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)[nH]c3c4ccc4[nH]c5ccccc5c43)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(N(C)C)cccc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c5ccccc5c5nc[nH]c5c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4cccc(N(C)C)c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4occc4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4[nH]c5ccccc5c(=O)c4c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3cnc3ccccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3oc3ccccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c3sc3ncccc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c5ccccc5c5[nH]cnc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4c5[nH]cnc5c5ccccc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cccc4[nH]c5ccccc5c(=O)c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccn[nH]3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3cn[nH]c3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3coc4cc5ccoc5cc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3coc4cc5[nH]ccc5cc34)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3c[nH]c4ccccc4c3=O)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3nc4ccccc4s3)cc2-1 +Cc1-c2ccccc2-c2ccc(-c3nccc4[nH]c5ccccc5c34)cc2-1 +Cc1-c2ccccc2-c2ccc(-n3c4ccccc4c(=O)c4ccccc43)cc2-1 +Cc1-c2ccccc2-c2ccc(-n3c4ccccc4c4cnccc43)cc2-1 +Cc1-c2ccccc2-c2cccc(-c3cc(=O)c4ccccc4[nH]3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc(N(C)C)cc4ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4c(cn3)[nH]c3ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cc4ccccc4cc3N(C)C)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc(N(C)C)c4ccccc34)c2-1 +C[C@@H]1c2c(-c3c1c(ccc3)c1ccc3c(c1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1cc3c(cc1)Nc1c4c5c(n(c6ccccc6)c4ccc1C3(C)C)cccc5)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1cc3c(n(c4ccccc4)c4c3cc3c(C(c5c(cccc5)N3)(C)C)c4)cc1)cccc2 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)N(C)c3ccccc3O4)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)oc3ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)c2-1 +C[C@H]1c2c(-c3c1c(ccc3)c1cc3n(c4ccccc4)c4c(c3cc1)c1c(C(c3c(cccc3)N1)(C)C)cc4)cccc2 +Cc1-c2ccccc2-c2cccc(-c3ccc4c5ccccc5c5nccnc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cc(N(C)C)ccc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4ccc(N(C)C)cc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4ccsc4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cc[nH]c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4cnc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4oc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4[nH]c5ccncc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4c(N(C)C)cccc34)c2-1 +C[C@@H]1c2c(-c3c1c(ccc3)c1c3c(C(c4c(c5c6c(n(c7ccccc7)c5cc4)cccc6)N3)(C)C)ccc1)cccc2 +C[C@H]1c2c(-c3c1c(ccc3)c1c3c(Sc4c(cccc4)N3)ccc1)cccc2 +C[C@@H]1c2c(-c3c1c(ccc3)c1c3c(n(c4ccccc4)c4c3c3c(C(c5c(cccc5)N3)(C)C)cc4)ccc1)cccc2 +Cc1-c2ccccc2-c2cccc(-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cccc(N(C)C)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4ccsc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cc[nH]c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4cnc5ccccc5c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4occc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]c5ccccc5c(=O)c34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cccc4[nH]nnc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3ccccc3N)c2-1 +Cc1-c2ccccc2-c2cccc(-c3cnc4sc5ccccc5c4c3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4cc5scnc5cc4s3)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4ccccc4c4ccccc34)c2-1 +Cc1-c2ccccc2-c2cccc(-c3nc4ccccc4s3)c2-1 +Cc1-c2ccccc2-c2cccc(-n3c4ccncc4c4cnccc43)c2-1 +Cc1-c2ccccc2-c2cccc(-n3ccc(=O)c4ccccc43)c2-1 +Cc1-c2ccccc2-c2cccc(-n3cccn3)c2-1 +Cc1c(C)c(-c2c(F)c(F)c(F)c(F)c2F)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2c3ccoc3cc3ccoc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2c3[nH]cnc3cc3nc[nH]c23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cc(C#N)cc(C#N)c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cc3nc4ccoc4nc3[nH]2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc(-c3cnccn3)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc(C#N)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(c2)-c2ccccc2-s-3(=O)=O)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(c2)[nH]c2ncccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3c(n2)[nH]c2ccccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3ncc4ccccc4c3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccc3ncoc3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc(-c3ccccn3)n2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc(C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3c2-s(=O)(=O)-c2ccccc2-3)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3c2cnc2ccccc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cccc3ocnc23)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccccc2C(=O)C(F)(F)F)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2ccccc2C(=O)c2ccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cnc3ccccc3n2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-c2cnc3cccnc3c2)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2c3ccccc3c3cccnc32)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2ccc(=O)c3ccccc32)c2c(c1C)c1ccccc1n2C +Cc1c(C)c(-n2ccc3nc4ccoc4nc32)c2c(c1C)c1ccccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3c4nc[nH]c4cc4[nH]cnc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc(C#N)c(C#N)c(C#N)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc(C#N)cc(C#N)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4cccnc4c4ncccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4cnccc4[nH]3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4nc5cc[nH]c5nc4o3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cc4[nH]c5ccncc5c4cn3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc(C#N)c(C#N)c3C#N)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4c(c3)sc3ccccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4ccc5cccnc5c4n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccc4nccnc4c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(-c4ccccn4)n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(C(=O)C(F)(F)F)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4c(=O)cc[nH]c34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4c3[nH]c3cnccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc4nn[nH]c34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ccnc(-c4ccccn4)c3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cnc4nccnc4n3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3nccc4c3[nH]c3ccccc34)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3ncon3)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-n3cnc4nc5nc[nH]c5cc43)cccc1n2C +Cc1cc2c(c(C)c1C)c1c(-n3nnc4ccccc43)cccc1n2C +O=C1c2c(C(=O)N1c1cc3c4c(n(c3cc1)C)cc(C)c(c4C)C)cccc2 +Cc1cc2c(c(C)c1C)c1cc(-c3c(C#N)cccc3C#N)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4ccccc4s3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4nc5ccoc5nc4[nH]3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cc4[nH]ccc4cn3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)-c(C)-c3ccccc3-4)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4c(c3)sc3ccccc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4nccnc4c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccc4[nH]c5cnccc5c4c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc(C#N)c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc(C(=O)C(F)(F)F)c3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cccc4c3C(=O)c=cC4=O)ccc1n2C +O=C1c2c(C(=O)N1)cccc2c1cc2c3c(n(c2cc1)C)cc(C)c(c3C)C +Cc1cc2c(c(C)c1C)c1cc(-c3ccccc3C#N)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccnc4ncccc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ccon3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cncc4[nH]c5ccccc5c34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3cnoc3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3coc4cc5ccoc5cc34)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-c3ncon3)ccc1n2C +Cc1cc2c(c(C)c1C)c1cc(-n3c4ccccc4c4cccnc43)ccc1n2C +O=C1c2c(C(=O)N1c1ccc3c4c(n(c3c1)C)cc(C)c(c4C)C)cccc2 +O=C1C=CC(=O)N1c1ccc2c3c(n(c2c1)C)cc(C)c(c3C)C +Cc1cc2c(c(C)c1C)c1ccc(-c3c(C#N)cc(C#N)cc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3c4nc[nH]c4cc4[nH]cnc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc(C#N)cc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4c(=O)cc[nH]c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4ccsc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4nn[nH]c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4sccc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4[nH]c5cnccc5c4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccc4[nH]nnc4c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc4sc5ccccc5c34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cccc4[nH]ccc(=O)c34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3cnc4c(ccc5cccnc54)c3)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3c[nH]c4ccncc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3nccc4c3[nH]c3ccccc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3nccc4[nH]ccc34)cc1n2C +Cc1cc2c(c(C)c1C)c1ccc(-c3ncncc3C#N)cc1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cc4[nH]c5ccncc5c4cn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(C#N)c(C#N)c3C#N)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc(C#N)cc3C#N)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4ncccc4n3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4[nH]c5cnccc5c4c3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccc4[nH]ccc(=O)c4c3)c1n2C +O=C1c2c(C(=O)N1)cccc2c1c2c(c3c(n2C)cc(C)c(c3C)C)ccc1 +Cc1cc2c(c(C)c1C)c1cccc(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cccc4[nH]ccc(=O)c34)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cccnc3-c3ccccn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cnc4cccnc4c3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cncc4c3[nH]c3ccncc34)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3cscn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3ncc(C#N)cn3)c1n2C +Cc1cc2c(c(C)c1C)c1cccc(-c3nccc4[nH]ccc34)c1n2C +Cc1cccc2c1[nH]c1c(C)c(-c3c(C#N)cccc3C#N)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3c4ncoc4nc4ocnc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccc(F)cc5)n4)ccc3F)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc(C#N)c(C#N)c(C#N)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc4cccnc4c4ncccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cc4[nH]ccc4cn3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc(C#N)c(C#N)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc(C#N)cc3C#N)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc4sc5ccccc5c4c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccc4[nH]nnc4c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc(C(=O)C(F)(F)F)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3ncc3ccccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4c3[nH]c3ncccc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccc4ncoc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cccnc3-c3ccccn3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccnc(-c4ccccn4)c3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3ccno3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3cnc4ccccc4n3)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3coc4nc5[nH]ccc5nc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-c3c[nH]c4ccncc34)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-n3c4ccccc4c4cccnc43)ccc12 +Cc1cccc2c1[nH]c1c(C)c(-n3ccc(=O)c4ccccc43)ccc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3(C)-c4ccccc4-c4ccccc4-3)cc12 +O=C1C=C(C(=O)N1)c1cc2c3c(c(C)ccc3)[nH]c2c(C)c1 +Cc1cccc2c1[nH]c1c(C)cc(-c3c4[nH]cnc4nc4nc[nH]c34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cc(C#N)cc(C#N)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cc4[nH]c5ccncc5c4cn3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc(C#N)c(C#N)c3C#N)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc(C#N)cc3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)cc12 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c3c(c(C)ccc3)[nH]c2c(C)c1 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4c(c3)[nH]c3ncccc34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4nccnc4c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccc4ocnc4c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(-c4ccccn4)n3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(-c4cnccn4)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4c3-c(C)-c3ccccc3-4)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4c3ncc3ccccc34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cccc4[nH]c5ncccc5c34)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3ccon3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cnc(-c4ccccc4)cn3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3cnc4ccccc4n3)cc12 +Cc1cccc2c1[nH]c1c(C)cc(-c3csc4ccccc34)cc12 +O=C1c2c(C(=O)N1c1c3c4c(c(C)ccc4)[nH]c3c(C)cc1)cccc2 +Cc1cccc2c1[nH]c1c(C)ccc(-c3c4ccoc4cc4ccoc34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc(C#N)c(C#N)c(C#N)c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cc4[nH]ccc4cn3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(-c4cnccn4)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C#N)c(C#N)c3C#N)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C(=O)C(F)(F)F)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4c(=O)cc[nH]c4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4cnc5ccccc5c4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccc4[nH]nnc4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cccc4c3-c(C)-c3ccccc3-4)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cccc4[nH]c5ncccc5c34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3ccnc4cccnc34)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cnc4c(ccc5cccnc54)c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cnc4cccnc4c3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cncs3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3cscn3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-c3nc4cc5nc[nH]c5cc4[nH]3)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-n3cnc4cc5nc[nH]c5cc43)c12 +Cc1cccc2c1[nH]c1c(C)ccc(-n3cnc4nc5nc[nH]c5cc43)c12 +O=C1C=C(C(=O)N1)n1c2c(c3c1c(C)ccc3)cccc2C +Cc1cccc2c3cccc(C)c3n(-c3c4ncoc4nc4ocnc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3c4[nH]cnc4cc4nc[nH]c34)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccc(F)cc5)n4)ccc3F)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc(=O)c4ccccc4[nH]3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc4nc5cc[nH]c5nc4o3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cc4[nH]ccc4cn3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(c3)-c(C)-c3ccccc3-4)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(c3)-c3ccccc3-c-4C)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c(n3)[nH]c3ccccc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4ncc5ccccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4[nH]c5ncccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cccc4c3-c3ccccc3-s-4(=O)=O)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c12 +Cc1cccc2c3cccc(C)c3n(-c3ccno3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4ccccc4n3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4cccnc4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cnc4[nH]c5ccccc5c4c3)c12 +Cc1cccc2c3cccc(C)c3n(-c3cncc4[nH]c5ccccc5c34)c12 +Cc1cccc2c3cccc(C)c3n(-c3csc4ccccc34)c12 +Cc1cccc2c3cccc(C)c3n(-c3nc4nc5nc[nH]c5nc4[nH]3)c12 +Cc1cccc2c3cccc(C)c3n(-c3nccc4[nH]c5ccncc5c34)c12 +Cc1cccc2c3cccc(C)c3n(-n3ccc4nc5ccoc5nc43)c12 +CN(C)c1c(-c2(C)-c3ccccc3-c3ccccc3-2)ccc2ccccc12 +O=C1C=CC(=O)N1c1c(N(C)C)c2c(cc1)cccc2 +CN(C)c1c(-c2c3[nH]cnc3nc3nc[nH]c23)ccc2ccccc12 +CN(C)c1c(-c2cc(C#N)c(C#N)c(C#N)c2)ccc2ccccc12 +CN(C)c1c(-c2cc(F)ccc2-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)ccc2ccccc12 +CN(C)c1c(-c2cccc(C(=O)C(F)(F)F)c2)ccc2ccccc12 +CN(C)c1c(-c2cccc3c2[nH]c2ncccc23)ccc2ccccc12 +CN(C)c1c(-c2cccc3cnc4ccccc4c23)ccc2ccccc12 +CN(C)c1c(-c2cccc3ncoc23)ccc2ccccc12 +CN(C)c1c(-c2ccon2)ccc2ccccc12 +CN(C)c1c(-c2cnoc2)ccc2ccccc12 +CN(C)c1c(-c2c[nH]c3ccncc23)ccc2ccccc12 +CN(C)c1c(-c2nc3cc4nc[nH]c4cc3[nH]2)ccc2ccccc12 +CN(C)c1c(-c2nc3ccccc3o2)ccc2ccccc12 +CN(C)c1c(-n2c3ccccc3c3cccnc32)ccc2ccccc12 +CN(C)c1cc(-c2c3ncoc3nc3ocnc23)cc2ccccc12 +CN(C)c1cc(-c2c3[nH]cnc3nc3nc[nH]c23)cc2ccccc12 +CN(C)c1cc(-c2cc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2C(=O)c2ccccc2)c2ccccc2c1 +CN(C)c1cc(-c2cc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2C(=O)c2ccccc2)cc2ccccc12 +CN(C)c1cc(-c2cc(=O)c3ccccc3[nH]2)c2ccccc2c1 +CN(C)c1cc(-c2cc3cccnc3c3ncccc23)c2ccccc2c1 +CN(C)c1cc(-c2ccc(-c3cnccn3)cc2)c2ccccc2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(cccc2)cc(N(C)C)c1 +CN(C)c1cc(-c2ccc3c(c2)[nH]c2ncccc23)cc2ccccc12 +CN(C)c1cc(-c2ccc3c(cnc4ccccc43)c2)c2ccccc2c1 +CN(C)c1cc(-c2ccc3c(cnc4ccccc43)c2)cc2ccccc12 +CN(C)c1cc(-c2ccc3c(n2)[nH]c2ccccc23)cc2ccccc12 +CN(C)c1cc(-c2ccc3ncoc3c2)cc2ccccc12 +CN(C)c1cc(-c2ccc3nn[nH]c3c2)c2ccccc2c1 +CN(C)c1cc(-c2ccc3[nH]c4cnccc4c3c2)cc2ccccc12 +CN(C)c1cc(-c2cccc(-c3cnccn3)c2)c2ccccc2c1 +CN(C)c1cc(-c2cccc(C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)c2)cc2ccccc12 +CN(C)c1cc(-c2cccc3c(=O)cc[nH]c23)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2C(=O)c=cC3=O)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2ncc2ccccc23)cc2ccccc12 +CN(C)c1cc(-c2cccc3c2[nH]c2cnccc23)c2ccccc2c1 +CN(C)c1cc(-c2cccc3c2[nH]c2cnccc23)cc2ccccc12 +CN(C)c1cc(-c2cccc3nccnc23)c2ccccc2c1 +CN(C)c1cc(-c2cccc3ocnc23)c2ccccc2c1 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c2ccccc2c1 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc2ccccc12 +CN(C)c1cc(-c2cccnc2-c2ccccn2)c2ccccc2c1 +CN(C)c1cc(-c2ccnc(-c3ccccn3)c2)c2ccccc2c1 +CN(C)c1cc(-c2ccnc3c2ccc2cccnc23)c2ccccc2c1 +CN(C)c1cc(-c2ccnc3cccnc23)c2ccccc2c1 +CN(C)c1cc(-c2coc3nc4[nH]ccc4nc23)cc2ccccc12 +CN(C)c1cc(-c2csc3ccccc23)c2ccccc2c1 +CN(C)c1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)c2ccccc2c1 +CN(C)c1cc(-c2nccs2)cc2ccccc12 +CN(C)c1cc(-n2cnc3cc4nc[nH]c4cc32)cc2ccccc12 +CN(C)c1cc2ccccc2cc1-c1(C)-c2ccccc2-c2ccccc2-1 +O=C1C=C(C(=O)N1)c1c(N(C)C)cc2c(c1)cccc2 +O=C1c2c(C(=O)N1c1c(N(C)C)cc3c(c1)cccc3)cccc2 +O=C1C=CC(=O)N1c1c(N(C)C)cc2c(c1)cccc2 +CN(C)c1cc2ccccc2cc1-c1c(C#N)cc(C#N)cc1C#N +CN(C)c1cc2ccccc2cc1-c1c(F)c(F)c(F)c(F)c1F +CN(C)c1cc2ccccc2cc1-c1cc(C#N)c(C#N)c(C#N)c1 +CN(C)c1cc2ccccc2cc1-c1cc2c3c(c1)Oc1ccccc1B3c1ccccc1O2 +CN(C)c1cc2ccccc2cc1-c1cc2ccccc2s1 +CN(C)c1cc2ccccc2cc1-c1cc2cnccc2[nH]1 +CN(C)c1cc2ccccc2cc1-c1cc2nc3ccoc3nc2[nH]1 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)-c1ccccc1-s-2(=O)=O +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)-s(=O)(=O)-c1ccccc1-2 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)B1c3ccccc3Oc3cccc(c31)O2 +CN(C)c1cc2ccccc2cc1-c1ccc2c(c1)Oc1cccc3c1B2c1ccccc1O3 +CN(C)c1cc2ccccc2cc1-c1ccc2cnc3ccccc3c2c1 +CN(C)c1cc2ccccc2cc1-c1cccc2ocnc12 +CN(C)c1cc2ccccc2cc1-c1ccnc2c1ccc1cccnc12 +CN(C)c1cc2ccccc2cc1-c1ccnc2ncccc12 +CN(C)c1cc2ccccc2cc1-c1cncs1 +CN(C)c1cc2ccccc2cc1-c1coc2nc3[nH]ccc3nc12 +CN(C)c1cc2ccccc2cc1-c1nccnc1-c1ccccc1 +CN(C)c1cc2ccccc2cc1-n1cnc2nc3nc[nH]c3cc21 +CN(C)c1ccc(-c2=cC(=O)c3ccccc3C2=O)c2ccccc12 +CN(C)c1ccc(-c2c(F)c(F)c(F)c(F)c2F)c2ccccc12 +CN(C)c1ccc(-c2cc(-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)ccc2F)c2ccccc12 +CN(C)c1ccc(-c2cc3cnccc3[nH]2)c2ccccc12 +CN(C)c1ccc(-c2cc3[nH]c4ccncc4c3cn2)c2ccccc12 +CN(C)c1ccc(-c2ccc(-c3cnccn3)cc2)c2ccccc12 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c(N(C)C)cc1)cccc2 +CN(C)c1ccc(-c2ccc3c(c2)sc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2ccc3ccsc3c2)c2ccccc12 +CN(C)c1ccc(-c2ccc3[nH]nnc3c2)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2ncc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2sc2ccccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3c2[nH]c2cnccc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3nccnc23)c2ccccc12 +CN(C)c1ccc(-c2cccc3ocnc23)c2ccccc12 +CN(C)c1ccc(-c2ccnc3cccnc23)c2ccccc12 +CN(C)c1ccc(-c2ccno2)c2ccccc12 +CN(C)c1ccc(-c2nccnc2-c2ccccc2)c2ccccc12 +CN(C)c1ccc(-c2ncon2)c2ccccc12 +CN(C)c1ccc(-n2c3ccncc3c3cnccc32)c2ccccc12 +CN(C)c1ccc(-n2ccc3cnccc32)c2ccccc12 +CN(C)c1ccc(-n2cnc3cc4nc[nH]c4cc32)c2ccccc12 +CN(C)c1ccc(-n2cnc3nc4nc[nH]c4nc32)c2ccccc12 +CN(C)c1ccc2c(-c3c(F)c(F)c(F)c(F)c3F)cccc2c1 +CN(C)c1ccc2c(-c3c4[nH]cnc4nc4nc[nH]c34)cccc2c1 +CN(C)c1ccc2c(-c3cc4[nH]c5ccncc5c4cn3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4c(=O)cc[nH]c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4c(c3)ncc3ccccc34)cccc2c1 +CN(C)c1ccc2c(-c3ccc4cccnc4n3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4cnc5ccccc5c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccc4[nH]ccc(=O)c4c3)cccc2c1 +CN(C)c1ccc2c(-c3ccccc3C(=O)c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc2c1 +CN(C)c1ccc2c(-c3ccno3)cccc2c1 +CN(C)c1ccc2c(-c3ncc(C#N)cn3)cccc2c1 +CN(C)c1ccc2c(-n3ccc(=O)c4ccccc43)cccc2c1 +CN(C)c1ccc2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc2c1 +CN(C)c1ccc2cc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)ccc2c1 +CN(C)c1ccc2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc2c1 +CN(C)c1ccc2cc(-c3cc4[nH]c5ccncc5c4cn3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc(-c4cnccn4)cc3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc4nn[nH]c4c3)ccc2c1 +CN(C)c1ccc2cc(-c3ccc4sccc4c3)ccc2c1 +CN(C)c1ccc2cc(-c3cccc4c3sc3ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3cccc4ocnc34)ccc2c1 +CN(C)c1ccc2cc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc2c1 +CN(C)c1ccc2cc(-c3ccccc3C#N)ccc2c1 +CN(C)c1ccc2cc(-c3cnc4nccnc4n3)ccc2c1 +CN(C)c1ccc2cc(-c3csc4ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3nc4ccccc4c4ccccc34)ccc2c1 +CN(C)c1ccc2cc(-c3nc4nc5nc[nH]c5nc4[nH]3)ccc2c1 +CN(C)c1ccc2cc(-c3nccs3)ccc2c1 +CN(C)c1ccc2cc(-n3c4ccccc4c4ccncc43)ccc2c1 +O=C1C=C(C(=O)N1)c1ccc2c(c1)cc(N(C)C)cc2 +CN(C)c1ccc2ccc(-c3cc(=O)c4ccccc4[nH]3)cc2c1 +CN(C)c1ccc2ccc(-c3ccc(C#N)c(C#N)c3C#N)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4c(c3)C(=O)c=cC4=O)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4c5c3Oc3ccccc3B5c3ccccc3O4)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4ncccc4n3)cc2c1 +CN(C)c1ccc2ccc(-c3ccc4[nH]c5ncccc5c4c3)cc2c1 +CN(C)c1ccc2ccc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cc2c1 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c1)cc(N(C)C)cc2 +CN(C)c1ccc2ccc(-c3cccc4ccsc34)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4[nH]c5ncccc5c34)cc2c1 +CN(C)c1ccc2ccc(-c3cccc4[nH]ccc(=O)c34)cc2c1 +CN(C)c1ccc2ccc(-c3ccnc4ncccc34)cc2c1 +CN(C)c1ccc2ccc(-c3cncc4cc[nH]c34)cc2c1 +CN(C)c1ccc2ccc(-n3ccc4cnccc43)cc2c1 +CN(C)c1ccc2ccc(-n3cnc4nc5nc[nH]c5nc43)cc2c1 +CN(C)c1ccc2cccc(-c3c4[nH]cnc4cc4nc[nH]c34)c2c1 +CN(C)c1ccc2cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c2c1 +CN(C)c1ccc2cccc(-c3cc(F)ccc3-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)c2c1 +CN(C)c1ccc2cccc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)c2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccc(N(C)C)c2)ccc1 +CN(C)c1ccc2cccc(-c3ccc4c(c3)[nH]c3ncccc34)c2c1 +CN(C)c1ccc2cccc(-c3ccc4c(n3)[nH]c3ccccc34)c2c1 +CN(C)c1ccc2cccc(-c3ccc4ncoc4c3)c2c1 +CN(C)c1ccc2cccc(-c3cccc(C(=O)C(F)(F)F)c3)c2c1 +CN(C)c1ccc2cccc(-c3cccc4c(=O)cc[nH]c34)c2c1 +CN(C)c1ccc2cccc(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)c2c1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc(N(C)C)c2)ccc1 +CN(C)c1ccc2cccc(-c3cccc4ccsc34)c2c1 +CN(C)c1ccc2cccc(-c3cccnc3-c3ccccn3)c2c1 +CN(C)c1ccc2cccc(-c3ccnc4c3ccc3cccnc34)c2c1 +CN(C)c1ccc2cccc(-c3ccnc4cccnc34)c2c1 +CN(C)c1ccc2cccc(-c3cnc4c(ccc5cccnc54)c3)c2c1 +CN(C)c1ccc2cccc(-c3cnc4ncccc4c3)c2c1 +CN(C)c1ccc2cccc(-c3c[nH]c4ccncc34)c2c1 +CN(C)c1ccc2cccc(-c3nccs3)c2c1 +CN(C)c1ccc2cccc(-n3c4ccccc4c4ccncc43)c2c1 +CN(C)c1ccc2ccccc2c1-c1cc(C(=O)c2ccccc2)ccc1-c1nc(-c2ccc(F)cc2)nc(-c2ccc(F)cc2)n1 +CN(C)c1ccc2ccccc2c1-c1cc(F)ccc1-c1nc(-c2ccc(F)cc2)nc(-c2ccc(C(=O)c3ccccc3)cc2)n1 +CN(C)c1ccc2ccccc2c1-c1cc2nc3ccoc3nc2[nH]1 +CN(C)c1ccc2ccccc2c1-c1cc2nc3cc[nH]c3nc2o1 +CN(C)c1ccc2ccccc2c1-c1ccc(C#N)c(C#N)c1C#N +CN(C)c1ccc2ccccc2c1-c1ccc2c(cnc3ccccc32)c1 +CN(C)c1ccc2ccccc2c1-c1ccc2ccsc2c1 +CN(C)c1ccc2ccccc2c1-c1cccc(C#N)c1 +CN(C)c1ccc2ccccc2c1-c1cccc(C(=O)c2ccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc2)c1 +CN(C)c1ccc2ccccc2c1-c1cccc2c1-s(=O)(=O)-c1ccccc1-2 +O=C1c2c(C(=O)N1)cccc2c1c(N(C)C)ccc2c1cccc2 +CN(C)c1ccc2ccccc2c1-c1cnc2ccccc2n1 +CN(C)c1ccc2ccccc2c1-c1cncs1 +CN(C)c1ccc2ccccc2c1-c1ncon1 +CN(C)c1cccc2c(-c3c(C#N)cc(C#N)cc3C#N)cccc12 +CN(C)c1cccc2c(-c3cc(C(=O)c4ccccc4)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cccc12 +CN(C)c1cccc2c(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cccc12 +CN(C)c1cccc2c(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc12 +CN(C)c1cccc2c(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)cccc12 +CN(C)c1cccc2c(-c3ccc4ncc5ccccc5c4c3)cccc12 +CN(C)c1cccc2c(-c3ccc4ncccc4n3)cccc12 +CN(C)c1cccc2c(-c3ccc4[nH]nnc4c3)cccc12 +CN(C)c1cccc2c(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cccc12 +CN(C)c1cccc2c(-c3cccc4c3[nH]c3cnccc34)cccc12 +CN(C)c1cccc2c(-c3cccc4c3[nH]c3ncccc34)cccc12 +CN(C)c1cccc2c(-c3cccc4ccsc34)cccc12 +CN(C)c1cccc2c(-c3cccc4ncc5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3cccc4sc5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3cccc4[nH]ccc(=O)c34)cccc12 +CN(C)c1cccc2c(-c3ccccc3C(=O)C(F)(F)F)cccc12 +CN(C)c1cccc2c(-c3ccnc4cccnc34)cccc12 +CN(C)c1cccc2c(-c3cncc4[nH]c5ccccc5c34)cccc12 +CN(C)c1cccc2c(-c3c[nH]c4ccncc34)cccc12 +CN(C)c1cccc2c(-n3c4ccccc4c4ccncc43)cccc12 +CN(C)c1cccc2cc(-c3c(C#N)cccc3C#N)ccc12 +CN(C)c1cccc2cc(-c3ccc(-c4cnccn4)cc3)ccc12 +CN(C)c1cccc2cc(-c3ccc(C#N)cc3)ccc12 +CN(C)c1cccc2cc(-c3ccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)cc3)ccc12 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(c(N(C)C)ccc2)cc1 +CN(C)c1cccc2cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +CN(C)c1cccc2cc(-c3ccc4nn[nH]c4c3)ccc12 +CN(C)c1cccc2cc(-c3cccc(C#N)c3)ccc12 +CN(C)c1cccc2cc(-c3cccc4[nH]c5cnccc5c34)ccc12 +CN(C)c1cccc2cc(-c3cccc4[nH]nnc34)ccc12 +CN(C)c1cccc2cc(-c3ccccc3-c3cnccn3)ccc12 +CN(C)c1cccc2cc(-c3cnc4ncccc4c3)ccc12 +CN(C)c1cccc2cc(-c3coc4nc5[nH]ccc5nc34)ccc12 +CN(C)c1cccc2cc(-c3cscn3)ccc12 +CN(C)c1cccc2cc(-c3c[nH]c4ccccc4c3=O)ccc12 +CN(C)c1cccc2cc(-c3c[nH]c4ccncc34)ccc12 +CN(C)c1cccc2cc(-c3nccc4c3[nH]c3ccccc34)ccc12 +CN(C)c1cccc2cc(-c3nccc4[nH]ccc34)ccc12 +CN(C)c1cccc2cc(-c3ncncc3C#N)ccc12 +CN(C)c1cccc2ccc(-c3cc(=O)c4ccccc4[nH]3)cc12 +CN(C)c1cccc2ccc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cc12 +CN(C)c1cccc2ccc(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cc12 +CN(C)c1cccc2ccc(-c3cccc4c3[nH]c3ncccc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4ocnc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4sccc34)cc12 +CN(C)c1cccc2ccc(-c3cccc4[nH]c5ncccc5c34)cc12 +CN(C)c1cccc2ccc(-c3cccc4[nH]nnc34)cc12 +CN(C)c1cccc2ccc(-c3ccnc4cccnc34)cc12 +CN(C)c1cccc2ccc(-c3ccno3)cc12 +CN(C)c1cccc2ccc(-c3coc4cc5ccoc5cc34)cc12 +CN(C)c1cccc2ccc(-n3ccc(=O)c4ccccc43)cc12 +CN(C)c1cccc2cccc(-c3c(C#N)cc(C#N)cc3C#N)c12 +CN(C)c1cccc2cccc(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)c12 +CN(C)c1cccc2cccc(-c3cc(C#N)cc(C#N)c3)c12 +CN(C)c1cccc2cccc(-c3cc4cc5occc5cc4o3)c12 +CN(C)c1cccc2cccc(-c3ccc(C#N)cc3C#N)c12 +CN(C)c1cccc2cccc(-c3ccc4cccnc4n3)c12 +CN(C)c1cccc2cccc(-c3ccc4ocnc4c3)c12 +CN(C)c1cccc2cccc(-c3cccc4c3[nH]c3ncccc34)c12 +CN(C)c1cccc2cccc(-c3cccc4[nH]c5ncccc5c34)c12 +CN(C)c1cccc2cccc(-c3coc4cc5ccoc5cc34)c12 +CN(C)c1cccc2cccc(-c3coc4nc5[nH]ccc5nc34)c12 +CN(C)c1cccc2cccc(-c3nc4ccccc4c4ccccc34)c12 +CN(C)c1cccc2cccc(-c3nc4ccccc4o3)c12 +CN(C)c1cccc2cccc(-c3nccc4[nH]c5ccncc5c34)c12 +CN(C)c1cccc2cccc(-c3ncncc3C#N)c12 +CN(C)c1cccc2cccc(-n3c4ccccc4c4ccncc43)c12 +CN(C)c1cccc2cccc(-n3ccc4nc5ccoc5nc43)c12 +CN(C)c1cccc2cccc(-n3cnc4cc5nc[nH]c5cc43)c12 +CN(C)c1cccc2cccc(-n3cnc4nc5nc[nH]c5nc43)c12 +CN1c2ccccc2N(C)c2c(-c3=cC(=O)c4ccccc4C3=O)cccc21 +CN1c2ccccc2N(C)c2c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(C(=O)c6ccccc6)cc5)n4)ccc3F)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc4[nH]c5ccncc5c4cn3)cccc21 +CN1c2ccccc2N(C)c2c(-c3cc4[nH]ccc4cn3)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4c(c3)sc3ccccc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4cccnc4n3)cccc21 +CN1c2ccccc2N(C)c2c(-c3ccc4ncc5ccccc5c4c3)cccc21 +O=C1c2c(C(=O)N1)cccc2c1c2N(C)c3c(N(C)c2ccc1)cccc3 +CN1c2ccccc2N(C)c2c(-c3cccc4ocnc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3cnc4cccnc4c3)cccc21 +CN1c2ccccc2N(C)c2c(-c3c[nH]c4nc5occc5nc34)cccc21 +CN1c2ccccc2N(C)c2c(-c3ncc(C#N)cn3)cccc21 +CN1c2ccccc2N(C)c2c1cccc2-n1ccc(=O)c2ccccc21 +CN1c2ccccc2N(C)c2c1cccc2-n1nnc2ccccc21 +CN1c2ccccc2N(C)c2cc(-c3=cC(=O)c4ccccc4C3=O)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cc4ccccc4s3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc(C#N)c(C#N)c3C#N)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccc4ncoc4c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc(C(=O)c4ccc(-c5nc(-c6ccc(F)cc6)nc(-c6ccc(F)cc6)n5)cc4)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cccc4ccsc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ccnc(-c4ccccn4)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cnc4c(ccc5cccnc54)c3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cncc(-c4ccccc4)n3)ccc21 +CN1c2ccccc2N(C)c2cc(-c3cncc4[nH]c5ccccc5c34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3csc4ccccc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3c[nH]c4nc5occc5nc34)ccc21 +CN1c2ccccc2N(C)c2cc(-c3ncon3)ccc21 +CN1c2ccccc2N(C)c2cc(-n3ccc(=O)c4ccccc43)ccc21 +CN1c2ccccc2N(C)c2cc(-n3ccc4cnccc43)ccc21 +O=C1C=C(C(=O)N1)c1c2Oc3c(N(C)c2ccc1)cccc3 +CN1c2ccccc2Oc2c(-c3c(C#N)cc(C#N)cc3C#N)cccc21 +CN1c2ccccc2Oc2c(-c3cc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)ccc3C(=O)c3ccccc3)cccc21 +CN1c2ccccc2Oc2c(-c3cc4cnccc4[nH]3)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)C(=O)c=cC4=O)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4c(c3)[nH]c3ncccc34)cccc21 +CN1c2ccccc2Oc2c(-c3ccc4nn[nH]c4c3)cccc21 +CN1c2ccccc2Oc2c(-c3cccc(-c4cnccn4)c3)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3B3c5ccccc5Oc5cccc(c53)O4)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4c3ncc3ccccc34)cccc21 +CN1c2ccccc2Oc2c(-c3cccc4cnc5ccccc5c34)cccc21 +CN1c2ccccc2Oc2c(-c3ccon3)cccc21 +CN1c2ccccc2Oc2c(-c3nc4nc5nc[nH]c5nc4[nH]3)cccc21 +CN1c2ccccc2Oc2c(-c3ncc(C#N)cn3)cccc21 +CN1c2ccccc2Oc2c(-c3ncno3)cccc21 +CN1c2ccccc2Oc2c1cccc2-n1nnc2ccccc21 +CN1c2ccccc2Oc2cc(-c3(C)-c4ccccc4-c4ccccc4-3)ccc21 +CN1c2ccccc2Oc2cc(-c3cc4[nH]c5ccncc5c4cn3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(-c4ccccn4)nc3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(C#N)c(C#N)c3C#N)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc(C(=O)C(F)(F)F)cc3)ccc21 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2Oc3c(N(C)c2cc1)cccc3 +CN1c2ccccc2Oc2cc(-c3ccc4ccc5cccnc5c4n3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4cccnc4n3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4ncc5ccccc5c4c3)ccc21 +CN1c2ccccc2Oc2cc(-c3ccc4nn[nH]c4c3)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc4[nH]c5ncccc5c34)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc4[nH]nnc34)ccc21 +CN1c2ccccc2Oc2cc(-c3cncc4c3[nH]c3ccncc34)ccc21 +CN1c2ccccc2Oc2cc(-c3cncc4cc[nH]c34)ccc21 +CN1c2ccccc2Oc2cc(-c3c[nH]c4ccncc34)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4ccccc4c4ccccc34)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4ccccc4o3)ccc21 +CN1c2ccccc2Oc2cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc21 +CN1c2ccccc2Oc2cc(-c3nccc4c3[nH]c3ccccc34)ccc21 +CN1c2ccccc2Oc2cc(-n3cnc4nc5nc[nH]c5cc43)ccc21 +CN1c2ccccc2Oc2ccc(-c3c(C#N)cccc3C#N)cc21 +CN1c2ccccc2Oc2ccc(-c3c4ccoc4cc4ccoc34)cc21 +CN1c2ccccc2Oc2ccc(-c3c4[nH]cnc4cc4nc[nH]c34)cc21 +CN1c2ccccc2Oc2ccc(-c3cc(F)ccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(C(=O)c5ccccc5)cc4)n3)cc21 +CN1c2ccccc2Oc2ccc(-c3cc4nc5ccoc5nc4[nH]3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc(C#N)c(C#N)c3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)cc21 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2Oc3c(N(C)c2c1)cccc3 +CN1c2ccccc2Oc2ccc(-c3ccc4ccsc4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3ccc4nn[nH]c4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3cccc4c3-c3ccccc3-s-4(=O)=O)cc21 +O=C1c2c(C(=O)N1)cccc2c1ccc2Oc3c(N(C)c2c1)cccc3 +CN1c2ccccc2Oc2ccc(-c3ccccc3-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)cc21 +CN1c2ccccc2Oc2ccc(-c3cnc4ncccc4c3)cc21 +CN1c2ccccc2Oc2ccc(-c3cncc4c3[nH]c3ccncc34)cc21 +CN1c2ccccc2Oc2ccc(-c3nc4ccccc4o3)cc21 +CN1c2ccccc2Oc2ccc(-c3nccnc3-c3ccccc3)cc21 +CN1c2ccccc2Oc2ccc(-c3ncon3)cc21 +CN1c2ccccc2Oc2ccc(-n3ccc4nc5ccoc5nc43)cc21 +CN1c2ccccc2Oc2cccc(-c3(C)-c4ccccc4-c4ccccc4-3)c21 +CN1c2ccccc2Oc2cccc(-c3=cC(=O)c4ccccc4C3=O)c21 +CN1c2ccccc2Oc2cccc(-c3c4[nH]cnc4nc4nc[nH]c34)c21 +CN1c2ccccc2Oc2cccc(-c3cc4cc5occc5cc4o3)c21 +CN1c2ccccc2Oc2cccc(-c3cc4nc5ccoc5nc4[nH]3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc(-c4ccccn4)nc3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(c3)C(=O)c=cC4=O)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4c(cnc5ccccc54)c3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4ccc5cccnc5c4n3)c21 +CN1c2ccccc2Oc2cccc(-c3ccc4nn[nH]c4c3)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4c3Oc3cccc5c3B4c3ccccc3O5)c21 +CN1c2ccccc2Oc2cccc(-c3cccc4ncc5ccccc5c34)c21 +CN1c2ccccc2Oc2cccc(-c3cnc4c(ccc5cccnc54)c3)c21 +CN1c2ccccc2Oc2cccc(-c3cnc4cccnc4c3)c21 +CN1c2ccccc2Oc2cccc(-c3nc4cc5ncoc5nc4o3)c21 +CN1c2ccccc2Oc2cccc(-c3nc4nc5nc[nH]c5nc4[nH]3)c21 +CN1c2ccccc2Oc2cccc(-c3ncc(C#N)cn3)c21 +CN1c2ccccc2Oc2cccc(-c3nccc4c3[nH]c3ccccc34)c21 +CN1c2ccccc2Oc2cccc(-n3ccc4cnccc43)c21 +CN1c2ccccc2Oc2cccc(-n3cnc4nc5nc[nH]c5cc43)c21 +Fc1c(c(c(c(F)c1N1c2c(CCc3c1cccc3)cccc2)F)F)F +Fc1c(F)c(F)c(-c2ccc3c(c2)c2ccccc2c2[nH]cnc32)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c(n2)sc2ncccc23)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3c4c2CCCN4CCC3)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3ccoc3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3cc[nH]c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3oc4ccccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2ccc3[nH]c4cnccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c2oc2ncccc23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4ccccc4c4[nH]cnc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4nccnc4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4nc[nH]c4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3c4[nH]cnc4c4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3ccoc23)c(F)c1F +Fc1c(F)c(F)c(-c2cccc3ncc4ccccc4c23)c(F)c1F +Fc1c(F)c(F)c(-c2ccn[nH]2)c(F)c1F +Fc1c(F)c(F)c(-c2cnc3sc4ccccc4c3c2)c(F)c1F +Fc1c(F)c(F)c(-c2cncc3c2[nH]c2ccccc23)c(F)c1F +Fc1c(F)c(F)c(-c2coc3cc4[nH]ccc4cc23)c(F)c1F +Fc1cc(-c2c3ccoc3cc3ccoc23)cc(F)c1F +Fc1cc(-c2ccc3sccc3c2)cc(F)c1F +Fc1cc(-c2ccc3[nH]nnc3c2)cc(F)c1F +Fc1cc(-c2cccc3[nH]c4cnccc4c23)cc(F)c1F +Fc1cc(-c2cccc3[nH]c4ncccc4c23)cc(F)c1F +Fc1cc(-c2cnc3ccccc3n2)cc(F)c1F +Fc1cc(-c2cnc3cccnc3c2)cc(F)c1F +Fc1cc(-c2csc3ccccc23)cc(F)c1F +Fc1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc(F)c1F +Fc1cc(-n2cnc3nc4nc[nH]c4nc32)cc(F)c1F +Fc1cc(-n2nnc3ccccc32)cc(F)c1F +Fc1ccc(-c2c3[nH]cnc3nc3nc[nH]c23)c(F)c1F +Fc1ccc(-c2cc3cc4occc4cc3o2)c(F)c1F +Fc1ccc(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c(F)c1F +Fc1ccc(-c2cccc3ncoc23)c(F)c1F +Fc1ccc(-c2cccnc2-c2ccccn2)c(F)c1F +Fc1ccc(-c2cncc3cc[nH]c23)c(F)c1F +Fc1ccc(-c2csc3ccccc23)c(F)c1F +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc5cc6cc[nH]c6cc5o4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cc5nc6ccoc6nc5[nH]4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccc6c7ccccc7[nH]c6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccncc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c(n4)oc4ccccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5c6ccccc6c6[nH]cnc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5ncc6ccccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5oc6ccccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5oc6ncccc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5[nH]c6ccncc6c5c4)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc(-c5cc6c7c(c5)CCCN7CCC6)c4)cc3)n2)cc1 +c1(c2nc(nc(n2)c2ccc(F)cc2)c2ccc(F)cc2)ccc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5c4oc4ncccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5c6[nH]cnc6c6ccccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5ncc6ccccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4cccc5[nH]c6cnccc6c45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4csc5ccccc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4c[nH]c5cc6occc6cc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4c[nH]c5nc6occc6nc45)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-n4c5ccccc5c5c6[nH]c7ccccc7c6ccc54)cc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c5ccoc5cc5ccoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c5ncoc5cc5ncoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5cc6cc[nH]c6cc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5ccccc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5ccccc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cc5nc6cc[nH]c6nc5o4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c(c4)sc4ncccc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c(c4)[nH]c4[nH]c6ccccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5c6ccccc6c6nc[nH]c6c5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4ccc5ncoc5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5c4[nH]c4ccncc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5cc[nH]c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5occc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4cccc5[nH]nnc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4c[nH]c5nc6occc6nc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4nc5cc6scnc6cc5s4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-c4nccc5[nH]c6ccccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-n4c5ccccc5c5c6ccccc6[nH]c54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3cccc(-n4c5ccccc5c5cnccc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3c4ccoc4cc4ccoc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3c4ncoc4cc4ncoc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4c5c(c3)CCCN5CCC4)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4nc5ccoc5nc4[nH]3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cc4[nH]c5ccccc5c4c4[nH]c5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(c3)Oc3ccccc3O4)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(n3)sc3ccccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c(n3)sc3ncccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4c5ccccc5c5[nH]cnc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4ccoc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccc4[nH]nnc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc(-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4c5ccccc5c5nccnc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4scnc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccccc3N(c3ccccc3)c3ccccc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3ccnc4sc5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cnc4sc5ncccc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-c3cn[nH]c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-n3ccc4ccccc43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cc5ccccc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cc5nc6ccoc6nc5[nH]4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5c(c4)c4ccccc4c4[nH]cnc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5c(c4)[nH]c4c5ccc5[nH]c6ccccc6c54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5ocnc5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccc5[nH]c6ccc7c8ccccc8[nH]c7c6c5c4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5c6ccccc6c6nccnc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5ccoc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5occc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4cccc5[nH]c6ccc7c8ccccc8[nH]c7c6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccccc4-c4cc5c6c(c4)CCCN6CCC5)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccnc5sc6ncccc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4ccnnc4)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4coc5cc6ccoc6cc45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-c4nccc5[nH]c6ccncc6c45)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)c(-n4nnc5ccccc54)c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3c4ncsc4cc4ncsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3[nH]cnc43)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3ccc5c6ccccc6[nH]c5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3cnccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c5ccccc5c5[nH]cnc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4ocnc4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4[nH]c5cnccc5c4c3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4c3sc3ncccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4ccsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4cnc5ccccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4ncsc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4sccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5ccncc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cccc4[nH]ccc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccnc4sc5ncccc5c34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3cnc4c5ccccc5c5ccccc5c4n3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3coc4cc5[nH]ccc5cc34)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3nc4c5ccccc5c5ccccc5c4[nH]3)n2)cc1 +Fc1ccc(-n2ccc3cnccc32)c(F)c1F +N#Cc1cc(-c2c3[nH]ccc3cc3ccoc23)cc(C#N)c1C#N +N#Cc1cc(-c2cc(=O)c3ccccc3[nH]2)cc(C#N)c1C#N +N#Cc1cc(-c2cc3ccccc3o2)cc(C#N)c1C#N +N#Cc1cc(-c2ccc(F)c(F)c2F)cc(C#N)c1C#N +N#Cc1c(c(C#N)cc(c1)c1ccc2CCc3c(cccc3)Nc2c1)C#N +N#Cc1cc(-c2ccc3c(c2)oc2ccccc23)cc(C#N)c1C#N +N#Cc1cc(-c2ccc3c(cnc4ccccc43)c2)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3c4nc[nH]c4c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3c4[nH]cnc4c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3ocnc23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3sccc23)cc(C#N)c1C#N +N#Cc1cc(-c2cccc3[nH]ccc(=O)c23)cc(C#N)c1C#N +N#Cc1cc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)cc(C#N)c1C#N +N#Cc1cc(-c2cncc3[nH]c4ccccc4c23)cc(C#N)c1C#N +N#Cc1cc(-c2coc3cc4ccoc4cc23)cc(C#N)c1C#N +N#Cc1cc(-c2csc3ccccc23)cc(C#N)c1C#N +N#Cc1cc(-c2c[nH]c3nc4occc4nc23)cc(C#N)c1C#N +N#Cc1cc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc(C#N)c1C#N +N#Cc1cc(-n2ccc(=O)c3ccccc32)cc(C#N)c1C#N +N#Cc1cc(C#N)c(-c2cc3cc4cc[nH]c4cc3o2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cc3cc4occc4cc3o2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3c(n2)sc2ccccc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3ncoc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3oc4ncccc4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3sccc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3scnc3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc(N(c3ccccc3)c3ccccc3)c2)c(C#N)c1 +N#Cc1cc(C#N)cc(C#N)c1c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1cc(C#N)c(-c2cccc3c4ccccc4c4nc[nH]c4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3ccoc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3ccsc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3oc4ccccc4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3occc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cccc3[nH]ccc(=O)c23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2cnc3sc4ccccc4c3c2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2c[nH]c3ccccc23)c(C#N)c1 +N#Cc1cc(C#N)c(-c2nc3cc4scnc4cc3s2)c(C#N)c1 +N#Cc1cc(C#N)c(-c2nccc3[nH]c4ccncc4c23)c(C#N)c1 +N#Cc1cc(C#N)c(-n2nnc3ccccc32)c(C#N)c1 +N#Cc1cc(C#N)cc(-c2c3cc[nH]c3cc3occc23)c1 +N#Cc1cc(C#N)cc(-c2c3ncsc3cc3ncsc23)c1 +N#Cc1cc(C#N)cc(-c2cc3c(cn2)[nH]c2ccccc23)c1 +N#Cc1cc(C#N)cc(-c2cc3nc4cc[nH]c4nc3o2)c1 +N#Cc1cc(C#N)cc(-c2cc3[nH]c4ccccc4c3cn2)c1 +N#Cc1cc(C#N)cc(-c2ccc(N)cc2)c1 +N#Cc1cc(C#N)cc(-c2ccc3c(=O)c4ccccc4[nH]c3c2)c1 +N#Cc1cc(C#N)cc(-c2ccc3cnc4ccccc4c3c2)c1 +N#Cc1cc(C#N)cc(-c2ccc3[nH]nnc3c2)c1 +N#Cc1cc(C#N)cc(-c2cccc(N)c2)c1 +N#Cc1cc(C#N)cc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3c4[nH]cnc4c4ccccc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3ccoc23)c1 +N#Cc1cc(C#N)cc(-c2cccc3cnc4ccccc4c23)c1 +N#Cc1cc(C#N)cc(-c2cccc3ncoc23)c1 +N#Cc1cc(C#N)cc(-c2cccc3occc23)c1 +N#Cc1cc(C#N)cc(-c2cc[nH]n2)c1 +N#Cc1cc(C#N)cc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1 +N#Cc1cc(C#N)cc(-c2cncc3c2[nH]c2ccncc23)c1 +N#Cc1cc(C#N)cc(-n2c3ccccc3c3cnccc32)c1 +N#Cc1ccc(-c2c3ccoc3cc3ccoc23)cc1C#N +N#Cc1ccc(-c2c3ncoc3cc3ncoc23)c(C#N)c1 +N#Cc1ccc(-c2c3[nH]ccc3cc3ccoc23)c(C#N)c1 +N#Cc1ccc(-c2c3[nH]ccc3cc3ccoc23)c(C#N)c1C#N +N#Cc1ccc(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)cc1 +N#Cc1ccc(-c2cc3cc4ccoc4cc3[nH]2)cc1C#N +N#Cc1ccc(-c2cc3cc4cc[nH]c4cc3o2)c(C#N)c1C#N +N#Cc1ccc(-c2cc3ccccc3o2)c(C#N)c1 +N#Cc1ccc(-c2cc3ccccc3[nH]2)cc1 +N#Cc1ccc(-c2cc3nc4ccoc4nc3[nH]2)c(C#N)c1C#N +N#Cc1ccc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cc3[nH]c4ccccc4c3cn2)cc1 +N#Cc1ccc(-c2ccc(F)c(F)c2F)cc1 +N#Cc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1C#N +N#Cc1ccc(-c2ccc(N)cc2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(=O)cc[nH]c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(=O)cc[nH]c3c2)cc1C#N +N#Cc1ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +N#Cc1ccc(-c2ccc3c(c2)oc2ccccc23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(c2)Oc2ccccc2O3)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(c2)oc2ncccc23)cc1 +N#Cc1ccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cc1 +N#Cc1ccc(-c2ccc3c(cnc4ccccc43)c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(cnc4ccccc43)c2)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(n2)oc2ccccc23)c(C#N)c1 +N#Cc1ccc(-c2ccc3c(n2)sc2ccccc23)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3c(n2)sc2ccccc23)cc1 +N#Cc1ccc(-c2ccc3c(n2)sc2ncccc23)c(C#N)c1 +N#Cc1ccc(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)cc1 +N#Cc1ccc(-c2ccc3cnc4ccccc4c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3oc4ccccc4c3c2)c(C#N)c1 +N#Cc1ccc(-c2ccc3occc3c2)cc1 +N#Cc1ccc(-c2ccc3[nH]c4ccc5c6ccccc6[nH]c5c4c3c2)c(C#N)c1C#N +N#Cc1ccc(-c2ccc3[nH]c4[nH]c5ccccc5c4c3c2)cc1C#N +N#Cc1ccc(-c2ccc3[nH]ccc3c2)c(C#N)c1C#N +N#Cc1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2)cc1C#N +N#Cc1ccc(-c2cccc(N)c2)c(C#N)c1C#N +N#Cc1ccc(-c2cccc(N)c2)cc1C#N +N#Cc1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3c(=O)c4ccccc4[nH]c23)cc1C#N +N#Cc1ccc(-c2cccc3c(=O)cc[nH]c23)c(C#N)c1C#N +N#Cc1c(c(C#N)c(cc1)c1c2c(Sc3c(cccc3)N2)ccc1)C#N +N#Cc1ccc(cc1)c1c2c(ccc1)Nc1c(S2)cccc1 +N#Cc1ccc(-c2cccc3c2cnc2ccccc23)cc1 +N#Cc1ccc(-c2cccc3c2oc2ccccc23)c(C#N)c1 +N#Cc1ccc(-c2cccc3c2sc2ncccc23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2cnccc23)cc1C#N +N#Cc1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)cc1 +N#Cc1ccc(-c2cccc3c4nc[nH]c4c4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3c4nc[nH]c4c4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3c4[nH]cnc4c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3cnc4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3ncc4ccccc4c23)cc1 +N#Cc1ccc(-c2cccc3ncoc23)cc1 +N#Cc1ccc(-c2cccc3oc4ncccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3oc4ncccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3ocnc23)cc1 +N#Cc1ccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c(C#N)c1 +N#Cc1ccc(-c2cccc3[nH]c4cnccc4c23)cc1 +N#Cc1ccc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)cc1C#N +N#Cc1ccc(-c2cccc3[nH]ccc23)cc1C#N +N#Cc1ccc(-c2cccc3[nH]nnc23)c(C#N)c1C#N +N#Cc1ccc(-c2cccc3[nH]nnc23)cc1C#N +N#Cc1ccc(-c2ccccc2N)c(C#N)c1 +N#Cc1ccc(-c2ccnc3sc4ccccc4c23)c(C#N)c1C#N +N#Cc1ccc(-c2ccnnc2)c(C#N)c1 +N#Cc1ccc(-c2cncc3[nH]c4ccccc4c23)c(C#N)c1 +N#Cc1ccc(-c2cn[nH]c2)c(C#N)c1 +N#Cc1ccc(-c2coc3cc4ccoc4cc23)cc1 +N#Cc1ccc(-c2coc3cc4[nH]ccc4cc23)c(C#N)c1C#N +N#Cc1ccc(-c2coc3ccccc23)cc1C#N +N#Cc1ccc(-c2c[nH]c3cc4occc4cc23)c(C#N)c1C#N +N#Cc1ccc(-c2c[nH]c3ccccc23)c(C#N)c1 +N#Cc1ccc(-c2c[nH]c3ccccc23)cc1C#N +N#Cc1ccc(-c2nc3cc4scnc4cc3s2)c(C#N)c1C#N +N#Cc1ccc(-c2nc3ccccc3c3ccccc23)c(C#N)c1 +N#Cc1ccc(-c2nc3ccccc3s2)c(C#N)c1 +N#Cc1ccc(-c2nc3ccccc3s2)c(C#N)c1C#N +N#Cc1ccc(-c2nc3ccccc3s2)cc1C#N +N#Cc1ccc(-c2nc3nc4nc[nH]c4nc3[nH]2)c(C#N)c1 +N#Cc1ccc(-c2nccc3c2[nH]c2ccccc23)c(C#N)c1 +N#Cc1ccc(-n2c3ccccc3c3c4ccccc4[nH]c32)cc1 +N#Cc1ccc(-n2c3ccccc3c3c4ccccc4[nH]c32)cc1C#N +N#Cc1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c(C#N)c1C#N +N#Cc1ccc(-n2c3ccccc3c3ccncc32)cc1C#N +N#Cc1ccc(-n2ccc(=O)c3ccccc32)cc1C#N +N#Cc1ccc(-n2ccc3cc4ccoc4cc32)cc1 +N#Cc1ccc(-n2ccc3cc4ccoc4cc32)cc1C#N +N#Cc1ccc(-n2cnc3c4ccccc4c4ccccc4c32)cc1C#N +N#Cc1cccc(c1)N1c2c(Sc3c1cccc3)cccc2 +N#Cc1cccc(-c2c3cc[nH]c3cc3occc23)c1 +N#Cc1cccc(-c2c3cc[nH]c3cc3occc23)c1C#N +N#Cc1cccc(-c2c3ncsc3cc3ncsc23)c1 +N#Cc1cccc(-c2cc3cc4ccoc4cc3[nH]2)c1C#N +N#Cc1cccc(-c2cc3cc4occc4cc3o2)c1C#N +N#Cc1cccc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)c1 +N#Cc1cccc(-c2cc3[nH]c4ccncc4c3cn2)c1 +N#Cc1cccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1 +N#Cc1cccc(-c2ccc3c(=O)cc[nH]c3c2)c1C#N +N#Cc1cccc(-c2ccc3c(c2)c2ccccc2c2[nH]cnc32)c1C#N +N#Cc1c(C#N)c(ccc1)c1cc2CCc3c(cccc3)Nc2cc1 +N#Cc1cccc(-c2ccc3c(c2)oc2ncccc23)c1 +N#Cc1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +N#Cc1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1C#N +N#Cc1cccc(-c2ccc3nn[nH]c3c2)c1C#N +N#Cc1cccc(-c2ccc3occc3c2)c1 +N#Cc1cccc(-c2ccc3occc3c2)c1C#N +N#Cc1cccc(-c2ccc3[nH]nnc3c2)c1C#N +N#Cc1cccc(-c2cccc(N)c2)c1C#N +N#Cc1cccc(-c2cccc3c(=O)cc[nH]c23)c1 +N#Cc1cccc(c1)c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1cccc(c1)c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1c(C#N)c(ccc1)c1c2c(ccc1)Nc1c(S2)cccc1 +N#Cc1cccc(-c2cccc3c4ccccc4c4nc[nH]c4c23)c1 +N#Cc1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1 +N#Cc1cccc(-c2cccc3c4ccccc4c4[nH]cnc4c23)c1C#N +N#Cc1cccc(-c2cccc3ccoc23)c1 +N#Cc1cccc(-c2cccc3ocnc23)c1 +N#Cc1cccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c1C#N +N#Cc1cccc(-c2cccc3[nH]c4[nH]c5ccccc5c4c23)c1 +N#Cc1cccc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)c1C#N +N#Cc1cccc(-c2ccnc3sc4ccccc4c23)c1 +N#Cc1cccc(-c2ccnc3sc4ccccc4c23)c1C#N +N#Cc1cccc(-c2ccnc3sc4ncccc4c23)c1 +N#Cc1cccc(-c2ccnc3sc4ncccc4c23)c1C#N +N#Cc1cccc(-c2cnc3c4ccccc4c4ccccc4c3n2)c1C#N +N#Cc1cccc(-c2cn[nH]c2)c1C#N +N#Cc1cccc(-c2c[nH]c3ccccc23)c1 +N#Cc1cccc(-c2nc3cc4scnc4cc3s2)c1 +N#Cc1cccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)c1 +N#Cc1cccc(-n2ccc3ccccc32)c1C#N +N#Cc1cccc(C#N)c1-c1c2[nH]ccc2cc2ccoc12 +N#Cc1cccc(C#N)c1-c1cc2nc3cc[nH]c3nc2o1 +N#Cc1cccc(C#N)c1-c1ccc2c(c1)oc1ncccc12 +N#Cc1cccc(C#N)c1-c1ccc2ncc3ccccc3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2occc2c1 +N#Cc1cccc(C#N)c1-c1ccc2sc3ncccc3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3ccc4c5ccccc5[nH]c4c3c2c1 +N#Cc1cccc(C#N)c1-c1ccc2[nH]c3ccncc3c2c1 +N#Cc1cccc(C#N)c1c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1cccc(C#N)c1-c1cccc2c3ccccc3c3nccnc3c12 +N#Cc1cccc(C#N)c1-c1cccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c12 +N#Cc1cccc(C#N)c1-c1cccc2[nH]ccc(=O)c12 +N#Cc1cccc(C#N)c1-c1ccccc1N(c1ccccc1)c1ccccc1 +N#Cc1cccc(C#N)c1-c1cn[nH]c1 +N#Cc1cccc(C#N)c1-c1nc2ccccc2s1 +N#Cc1cccc(C#N)c1-n1c2ccccc2c(=O)c2ccccc21 +N#Cc1cccc(C#N)c1-n1c2ccccc2c2c3ccccc3[nH]c21 +N#Cc1cccc(C#N)c1-n1c2ccccc2c2cnccc21 +N#Cc1cccc(C#N)c1-n1c2ccncc2c2cnccc21 +N#Cc1cccc(C#N)c1-n1ccc2nc3ccoc3nc21 +N#Cc1cccc(C#N)c1-n1cnc2nc3nc[nH]c3nc21 +N#Cc1ccccc1-c1c(-c2ccccc2)cc2c3c1CCCN3CCC2 +N#Cc1ccccc1-c1cc(F)c(F)c(F)c1 +N#Cc1ccccc1-c1cc2cc3cc[nH]c3cc2o1 +N#Cc1ccccc1-c1cc2[nH]c3ccncc3c2cn1 +N#Cc1ccccc1-c1ccc2c(c1)c1ccccc1c1[nH]cnc21 +N#Cc1ccccc1-c1ccc2scnc2c1 +N#Cc1ccccc1c1c2c(Sc3c(cccc3)N2)ccc1 +N#Cc1ccccc1-c1cccc2c3ccccc3c3nc[nH]c3c12 +N#Cc1ccccc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +N#Cc1ccccc1-c1cccc2c3[nH]cnc3c3ccccc3c12 +N#Cc1ccccc1-c1cccc2ncc3ccccc3c12 +N#Cc1ccccc1-c1cccc2[nH]c3[nH]c4ccccc4c3c12 +N#Cc1ccccc1-c1cccc2[nH]nnc12 +N#Cc1ccccc1-c1cc[nH]n1 +N#Cc1ccccc1-c1coc2cc3[nH]ccc3cc12 +N#Cc1ccccc1-c1c[nH]c2cc3occc3cc12 +N#Cc1ccccc1-n1c2ccccc2c2cnccc21 +N#Cc1cnc(-c2cc3ccccc3o2)nc1 +N#Cc1cnc(-c2cc3[nH]c4ccccc4c3c3[nH]c4ccccc4c23)nc1 +c1(C#N)cnc(nc1)c1cc2c(Sc3c(cccc3)N2)cc1 +N#Cc1cnc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)nc1 +N#Cc1cnc(-c2ccc3c(c2)Oc2ccccc2O3)nc1 +N#Cc1cnc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)nc1 +N#Cc1cnc(-c2ccc3sc4ncccc4c3c2)nc1 +N#Cc1cnc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)nc1 +N#Cc1cnc(-c2ccc3[nH]nnc3c2)nc1 +N#Cc1cnc(-c2cccc3c2sc2ncccc23)nc1 +N#Cc1cnc(-c2cccc3c2[nH]c2cnccc23)nc1 +N#Cc1cnc(-c2cccc3c4ccccc4c4[nH]cnc4c23)nc1 +N#Cc1cnc(-c2cccc3c4nccnc4c4ccccc4c23)nc1 +N#Cc1cnc(-c2cccc3ccsc23)nc1 +N#Cc1cnc(-c2cccc3ncc4ccccc4c23)nc1 +N#Cc1cnc(-c2cccc3ncsc23)nc1 +N#Cc1cnc(-c2cccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c23)nc1 +N#Cc1cnc(-c2cnc3sc4ncccc4c3c2)nc1 +N#Cc1cnc(-c2c[nH]c3nc4occc4nc23)nc1 +N#Cc1cnc(-c2nc3ccccc3c3ccccc23)nc1 +N#Cc1cnc(-n2c3ccccc3c3ccncc32)nc1 +N#Cc1cnc(-n2ccc(=O)c3ccccc32)nc1 +N#Cc1cncnc1-c1cc2[nH]c3ccccc3c2cn1 +N#Cc1cncnc1-c1ccc2c(c1)Oc1ccccc1O2 +N#Cc1cncnc1-c1ccc2ncoc2c1 +N#Cc1cncnc1-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +N#Cc1cncnc1-c1cccc(N(c2ccccc2)c2ccccc2)c1 +c1(C#N)cncnc1c1c2c(CCc3c(cccc3)N2)ccc1 +N#Cc1cncnc1-c1cccc2c1oc1ccccc12 +N#Cc1cncnc1-c1cccc2c1oc1ncccc12 +N#Cc1cncnc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +N#Cc1cncnc1-c1cccc2sccc12 +N#Cc1cncnc1-c1cccc2scnc12 +N#Cc1cncnc1-c1cccc2[nH]c3c(ccc4[nH]c5ccccc5c43)c12 +N#Cc1cncnc1-c1cccc2[nH]c3ccncc3c12 +N#Cc1cncnc1-c1cccc2[nH]nnc12 +N#Cc1cncnc1-c1nc2c3ccccc3c3ccccc3c2[nH]1 +N#Cc1cncnc1-c1nc2ccccc2o1 +N#Cc1cncnc1-c1nccc2c1[nH]c1ccccc12 +N#Cc1cncnc1-c1nccc2[nH]c3ccncc3c12 +N#Cc1cncnc1-n1c2ccccc2c2ccc3[nH]c4ccccc4c3c21 +N#Cc1cncnc1-n1c2ccncc2c2cnccc21 +N#Cc1cncnc1-n1ccc2nc3ccoc3nc21 +Nc1ccc(-c2c3ncoc3nc3ocnc23)cc1 +Nc1ccc(-c2ccc3c(c2)-s(=O)(=O)-c2ccccc2-3)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc(N)cc1 +Nc1ccc(-c2ccc3ncccc3n2)cc1 +Nc1ccc(-c2ccc3[nH]nnc3c2)cc1 +Nc1ccc(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)cc1 +Nc1ccc(-c2cccc(C(=O)C(F)(F)F)c2)cc1 +Nc1ccc(-c2cccc3ocnc23)cc1 +Nc1ccc(-c2cccc3[nH]c4ncccc4c23)cc1 +Nc1ccc(-c2cnc3nccnc3n2)cc1 +Nc1ccc(-c2nc3ccccc3o2)cc1 +Nc1ccc(-c2nc3nc4nc[nH]c4nc3[nH]2)cc1 +Nc1ccc(-n2c3ccncc3c3cnccc32)cc1 +Nc1ccc(-n2cnc3cc4nc[nH]c4cc32)cc1 +Nc1ccc(-n2cnc3nc4nc[nH]c4cc32)cc1 +Nc1cccc(-c2c(F)c(F)c(F)c(F)c2F)c1 +Nc1cccc(-c2c3ccoc3cc3ccoc23)c1 +Nc1cccc(-c2cc(=O)c3ccccc3[nH]2)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cccc(N)c1 +Nc1cccc(-c2ccc3c4c2Oc2ccccc2B4c2ccccc2O3)c1 +Nc1cccc(-c2ccc3cccnc3n2)c1 +Nc1cccc(-c2ccc3ncc4ccccc4c3c2)c1 +Nc1cccc(-c2ccc3ocnc3c2)c1 +Nc1cccc(-c2cccc(-c3ccccn3)n2)c1 +Nc1cccc(-c2cccc3sccc23)c1 +Nc1cccc(-c2ccon2)c1 +Nc1cccc(-c2cncc3cc[nH]c23)c1 +Nc1cccc(-c2coc3cc4ccoc4cc23)c1 +Nc1cccc(-c2nc3ccccc3o2)c1 +Nc1cccc(-n2ccc3nc4ccoc4nc32)c1 +Nc1ccccc1-c1c2[nH]cnc2nc2nc[nH]c12 +Nc1ccccc1-c1cc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)ccc1F +Nc1ccccc1-c1cc2c(cn1)[nH]c1ccccc12 +Nc1ccccc1-c1ccc(-c2ccccn2)nc1 +Nc1ccccc1-c1ccc(-c2cnccn2)cc1 +Nc1ccccc1-c1ccc2c(c1)B1c3ccccc3Oc3cccc(c31)O2 +Nc1ccccc1-c1ccc2c(c1)sc1ccccc12 +Nc1ccccc1-c1ccc2nccnc2c1 +Nc1ccccc1-c1ccc2sc3ccccc3c2c1 +Nc1ccccc1-c1ccc2[nH]c3cnccc3c2c1 +Nc1ccccc1-c1ccc2[nH]ccc(=O)c2c1 +Nc1ccccc1-c1cccc2nccnc12 +Nc1ccccc1-c1cccc2sc3ccccc3c12 +Nc1ccccc1-c1cccc2[nH]ccc(=O)c12 +Nc1ccccc1-c1ccccc1C(=O)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +Nc1ccccc1-c1cncc2[nH]c3ccccc3c12 +Nc1ccccc1-c1nc2cc3ncoc3nc2o1 +Nc1ccccc1-c1nc2ccccc2o1 +Nc1ccccc1-n1c2ccccc2c2ccncc21 +Nc1ccccc1-n1ccc2cnccc21 +O=C(c1ccc(-c2c(-c3ccccc3)cc3c4c2CCCN4CCC3)cc1)C(F)(F)F +O=C(c1ccc(-c2c3ccoc3cc3ccoc23)cc1)C(F)(F)F +O=C(c1ccc(-c2c3cc[nH]c3cc3occc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cc3[nH]c4ccccc4c3cn2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2cc3[nH]c4ccncc4c3cn2)cc1)C(F)(F)F +O=C(c1ccc(-c2ccc3c(=O)cc[nH]c3c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(cc1)c1cc2c(Sc3c(cccc3)N2)cc1)C(F)(F)F +O=C(c1ccc(-c2ccc3c(c2)c2ccccc2c2nccnc32)cc1)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1cc2CCc3c(cccc3)Nc2cc1 +O=C(c1ccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2ccc3c(n2)sc2ccccc23)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2ccc3oc4ccccc4c3c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c(=O)cc[nH]c23)cc1)C(F)(F)F +O=C(c1ccc(cc1)c1c2CCc3c(cccc3)Nc2ccc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c2sc2ncccc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3ccoc23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3oc4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2cccc3[nH]c4cnccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2ccnc3oc4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2ccnnc2)cc1)C(F)(F)F +O=C(c1ccc(-c2cnc3oc4ccccc4c3c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cnc3sc4ccccc4c3c2)cc1)C(F)(F)F +O=C(c1ccc(-c2cncc3[nH]c4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-c2cn[nH]c2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2c[nH]c(=O)[nH]2)cc1)C(F)(F)F +O=C(c1ccc(-c2c[nH]c3ccccc3c2=O)cc1)C(F)(F)F +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2c3ncsc3cc3ncsc23)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccc(cc1)c1c2c(Sc3c(cccc3)N2)ccc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3c2cnc2ccccc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3c2[nH]c2[nH]c4ccccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3cc[nH]c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3cnc4ccccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3nn[nH]c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3sc4ncccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2cccc3[nH]c4cnccc4c23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2coc3cc4ccoc4cc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2coc3ccccc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2c[nH]c3nc4occc4nc23)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-c2nc3ccccc3o2)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-n2c3ccccc3c3c4[nH]c5ccccc5c4ccc32)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccc(-n2ccc3nc4ccoc4nc32)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)N1c2c(Sc3c1cccc3)cccc2 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)N1c2c(CCc3c1cccc3)cccc2 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3c(cn2)[nH]c2ccccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3ccccc3[nH]2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cc3nc4ccoc4nc3[nH]2)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)cccc(c1)c1ccc2c(Sc3c(cccc3)N2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)Oc2ccccc2O3)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2ccc4c5ccccc5[nH]c4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)[nH]c2cnccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(n2)oc2ccccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3ccsc3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3occc3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c2oc2ncccc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c4ccccc4c4nccnc4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3cc[nH]c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3ncsc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3nn[nH]c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3[nH]c4ccccc4c(=O)c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3[nH]nnc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2c[nH]c3nc4occc4nc23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2nc3ccccc3s2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2nccc3[nH]c4ccccc4c23)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-n2c3ccccc3c3cnccc32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-n2ccc3cc4ccoc4cc32)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c2cc[nH]c2cc2occc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c2ncoc2cc2ncoc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc(-c2cc3c4c(c2)CCCN4CCC3)cc1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2)ccccc1c1ccc2c(Sc3c(cccc3)N2)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)ncc1ccccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)oc1ncccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)sc1ncccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)[nH]c1ccc3c4ccccc4[nH]c3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c(n1)oc1ccccc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2c3ccccc3c3nc[nH]c3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2cnc3ccccc3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccc2ncoc2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cccc2c3nccnc3c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cccc2ccoc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccccc1N(c1ccccc1)c1ccccc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1ccnnc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cnc2oc3ccccc3c2c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1cncc2[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1c[nH]c2cc3occc3cc12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1nccc2[nH]c3ccccc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-c1nccc2[nH]c3ccncc3c12 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1c2ccccc2c2c3[nH]c4ccccc4c3ccc21 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1c2ccccc2c2cnccc21 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1ccccc1-n1ccc2ccccc21 +O=C(c1ccc(-c2nc3ccccc3c3ccccc23)cc1)C(F)(F)F +O=C(c1ccc(-c2nccc3[nH]c4ccccc4c23)cc1)C(F)(F)F +O=C(c1ccc(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)cc1)C(F)(F)F +O=C(c1ccc(-n2nnc3ccccc32)cc1)C(F)(F)F +O=C(c1cccc(-c2c3ncoc3cc3ncoc23)c1)C(F)(F)F +O=C(c1cccc(-c2c3ncsc3cc3ncsc23)c1)C(F)(F)F +O=C(c1cccc(-c2cc(=O)c3ccccc3[nH]2)c1)C(F)(F)F +O=C(c1cccc(-c2cc3cc4cc[nH]c4cc3o2)c1)C(F)(F)F +O=C(c1cccc(-c2cc3[nH]c4ccncc4c3cn2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc(-c3cc4c5c(c3)CCCN5CCC4)cc2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3c(c2)Oc2ccccc2O3)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3c4c2CCCN4CCC3)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3ncc4ccccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3oc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3sc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2ccc3[nH]c4ccccc4c(=O)c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2cccc(-c3cc4c5c(c3)CCCN5CCC4)c2)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3c(=O)cc[nH]c23)c1)C(F)(F)F +O=C(c1cccc(c1)c1c2c(CCc3c(cccc3)N2)ccc1)C(F)(F)F +O=C(c1cccc(-c2cccc3ccsc23)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3nn[nH]c23)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3oc4ncccc4c23)c1)C(F)(F)F +O=C(c1cccc(-c2ccccc2-c2cc3c4c(c2)CCCN4CCC3)c1)C(F)(F)F +O=C(c1cccc(-c2cnc3sc4ccccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2cnc3sc4ncccc4c3c2)c1)C(F)(F)F +O=C(c1cccc(-c2coc3cc4[nH]ccc4cc23)c1)C(F)(F)F +O=C(c1cccc(-c2csc3ccccc23)c1)C(F)(F)F +O=C(c1cccc(-c2c[nH]c3ccccc23)c1)C(F)(F)F +O=C(c1cccc(-c2c[nH]c3nc4occc4nc23)c1)C(F)(F)F +O=C(c1cccc(-c2nc3c4ccccc4c4ccccc4c3[nH]2)c1)C(F)(F)F +O=C(c1cccc(-n2c3ccccc3c(=O)c3ccccc32)c1)C(F)(F)F +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)c(c3)N3c4c(CCc5c3cccc5)cccc4)cc2)ccccc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cc5c(cn4)[nH]c4ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)ncc4ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)Oc4ccccc4O5)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)[nH]c4[nH]c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5ncoc5c4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5oc6ccccc6c5c4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4sc4ncccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4[nH]c4ccncc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c6ccccc6c6[nH]cnc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c6nccnc6c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5ccsc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5cnc6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5sc6ncccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5scnc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5[nH]c6ccccc6c(=O)c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cc[nH]n4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cncc5[nH]c6ccccc6c45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4coc5cc6[nH]ccc6cc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4coc5ccccc45)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-n4c5ccccc5c5ccncc54)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-n4ccc(=O)c5ccccc54)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c(-c3ccccc3)cc3c4c2CCCN4CCC3)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c3ncsc3cc3ncsc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cc3c4ccccc4[nH]c3c3c2[nH]c2ccccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc(F)c(F)c2F)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(c2)c2ccccc2c2nccnc32)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(c2)oc2ncccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c(n2)sc2ncccc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3c4ccccc4c4[nH]cnc4c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3nn[nH]c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3[nH]c4ccncc4c3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccc3[nH]nnc3c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3c4[nH]cnc4c4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3cnc4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cccc3sc4ncccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2ccnc3oc4ccccc4c23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2cn[nH]c2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2coc3cc4[nH]ccc4cc23)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2c[nH]c(=O)[nH]2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2nc3c4ccccc4c4ccccc4c3[nH]2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-c2nc3cc4ocnc4cc3o2)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)c(-n2ccc3cc4ccoc4cc32)c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cc2c3ccccc3[nH]c2c2c1[nH]c1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2c(=O)cc[nH]c2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2c(n1)sc1ncccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2occc2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2sc3ncccc3c2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccc2[nH]ccc2c1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc(N(c2ccccc2)c2ccccc2)c1 +c1(C(=O)c2ccc(c3nc(nc(n3)c3ccc(F)cc3)c3ccc(F)cc3)cc2c2c3c(Sc4c(cccc4)N3)ccc2)ccccc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1cnc1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1Oc1ccccc1O2 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c1oc1ncccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c3nc[nH]c3c3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2c3[nH]cnc3c3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2cnc3ccccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2scnc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cccc2[nH]c3cnccc3c12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1ccccc1-c1cc2c3c(c1)CCCN3CCC2 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cnc2c3ccccc3c3ccccc3c2n1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1cncc2c1[nH]c1ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1coc2cc3ccoc3cc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1coc2ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1c[nH]c2ccccc12 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1nc2cc3ocnc3cc2o1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-c1nc2cc3scnc3cc2s1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-n1ccc2cc3ccoc3cc21 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1-n1cnc2c3ccccc3c3ccccc3c21 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4cc5cc[nH]c5cc4o3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4cc5occc5cc4o3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cc4[nH]c5ccccc5c4cn3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)c3ccccc3c3nccnc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)ncc3ccccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)[nH]c3ccncc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4[nH]ccc4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3ncc3ccccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3c4ccc4[nH]c5ccccc5c43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3ccc5c6ccccc6[nH]c5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3ccncc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3cnccc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c3[nH]c3[nH]c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4c5nccnc5c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4ccsc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4nn[nH]c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4ocnc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5ccccc5c(=O)c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccc4[nH]c5cnccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cccnn3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccnc4oc5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccn[nH]3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cnc4sc5ccccc5c4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3cnc4sc5ncccc5c4c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3coc4cc5[nH]ccc5cc34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3c[nH]c(=O)[nH]3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3nccc4[nH]c5ccccc5c34)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c(=O)c4ccccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c4c5[nH]c6ccccc6c5ccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccccc4c4cnccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3c4ccncc4c4cnccc43)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-n3ccc(=O)c4ccccc43)n2)cc1 +O=C(c1ccccc1-c1c(-c2ccccc2)cc2c3c1CCCN3CCC2)C(F)(F)F +O=C(c1ccccc1-c1cc(=O)c2ccccc2[nH]1)C(F)(F)F +O=C(c1ccccc1-c1cc2nc3cc[nH]c3nc2o1)C(F)(F)F +O=C(c1ccccc1c1cc2c(Sc3c(cccc3)N2)cc1)C(F)(F)F +O=C(c1ccccc1c1cc2CCc3c(cccc3)Nc2cc1)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)oc1ncccc12)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)[nH]c1c2ccc2[nH]c3ccccc3c21)C(F)(F)F +O=C(c1ccccc1-c1ccc2c(c1)[nH]c1[nH]c3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1ccc2occc2c1)C(F)(F)F +O=C(c1ccccc1-c1cccc2c(=O)cc[nH]c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2c1[nH]c1c2ccc2[nH]c3ccccc3c21)C(F)(F)F +O=C(c1ccccc1-c1cccc2c3nccnc3c3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2ccoc12)C(F)(F)F +O=C(c1ccccc1-c1cccc2oc3ccccc3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2[nH]c3ccc4c5ccccc5[nH]c4c3c12)C(F)(F)F +O=C(c1ccccc1-c1cccc2[nH]c3ccncc3c12)C(F)(F)F +O=C(c1ccccc1-c1ccccc1N(c1ccccc1)c1ccccc1)C(F)(F)F +O=C(c1ccccc1-c1coc2nc3[nH]ccc3nc12)C(F)(F)F +O=C(c1ccccc1-c1c[nH]c2cc3occc3cc12)C(F)(F)F +O=C(c1ccccc1-c1c[nH]c2ccccc2c1=O)C(F)(F)F +O=C(c1ccccc1-c1nc2c3ccccc3c3ccccc3c2[nH]1)C(F)(F)F +O=C(c1ccccc1-c1nccc2[nH]c3ccncc3c12)C(F)(F)F +O=C(c1ccccc1-n1c2ccccc2c(=O)c2ccccc21)C(F)(F)F +O=C(c1ccccc1-n1ccc(=O)c2ccccc21)C(F)(F)F +O=C(c1ccccc1-n1cnc2nc3nc[nH]c3nc21)C(F)(F)F +O=c1c(-c2c3[nH]ccc3cc3ccoc23)c[nH]c2ccccc12 +O=c1c(-c2c3[nH]cnc3nc3nc[nH]c23)c[nH]c2ccccc12 +O=c1c(-c2cc(F)c(F)c(F)c2)c[nH]c2ccccc12 +O=c1c(-c2cc3c4c(c2)CCCN4CCC3)c[nH]c2ccccc12 +O=c1c(-c2cc3ccccc3o2)c[nH]c2ccccc12 +O=c1c(-c2cc3ccccc3s2)c[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]cc1c1cc2CCc3c(cccc3)Nc2cc1 +O=c1c(-c2ccc3c(c2)[nH]c2c3ccc3[nH]c4ccccc4c32)c[nH]c2ccccc12 +O=c1c(-c2ccc3c(c2)[nH]c2ncccc23)c[nH]c2ccccc12 +O=c1c(-c2ccc3c4c2CCCN4CCC3)c[nH]c2ccccc12 +O=c1c(-c2ccc3cc[nH]c3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3oc4ccccc4c3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3sccc3c2)c[nH]c2ccccc12 +O=c1c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)c[nH]c2ccccc12 +O=c1c(-c2cccc(-c3cnccn3)c2)c[nH]c2ccccc12 +O=c1c(-c2cccc3c(=O)cc[nH]c23)c[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]cc1c1c2c(CCc3c(cccc3)N2)ccc1 +O=c1c(-c2cccc3c2ncc2ccccc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2Oc2ccccc2O3)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2sc2ncccc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3c2[nH]c2c3ccc3[nH]c4ccccc4c32)c[nH]c2ccccc12 +O=c1c(-c2cccc3ccoc23)c[nH]c2ccccc12 +O=c1c(-c2cccc3cnc4ccccc4c23)c[nH]c2ccccc12 +O=c1c(-c2ccnc(-c3ccccn3)c2)c[nH]c2ccccc12 +O=c1c(-c2ccnc3ncccc23)c[nH]c2ccccc12 +O=c1c(-c2ccnc3[nH]c4ccccc4c23)c[nH]c2ccccc12 +O=c1c(-c2ccno2)c[nH]c2ccccc12 +O=c1c(-c2cnc3cccnc3c2)c[nH]c2ccccc12 +O=c1c(-c2c[nH]c3ccccc23)c[nH]c2ccccc12 +O=c1c(-c2nc3cc4scnc4cc3s2)c[nH]c2ccccc12 +O=c1c(-c2nc3ccccc3s2)c[nH]c2ccccc12 +O=c1c(-c2nc3nc4nc[nH]c4cc3[nH]2)c[nH]c2ccccc12 +O=c1c(-c2nccc3[nH]c4ccncc4c23)c[nH]c2ccccc12 +O=c1c(-n2c3ccccc3c3ccc4[nH]c5ccccc5c4c32)c[nH]c2ccccc12 +O=c1c(-n2c3ccncc3c3cnccc32)c[nH]c2ccccc12 +O=c1c(-n2ccc3cnccc32)c[nH]c2ccccc12 +O=c1c(-n2cc[nH]c2=O)c[nH]c2ccccc12 +O=c1c(-n2cnc3nc4nc[nH]c4nc32)c[nH]c2ccccc12 +O=C1c2c(C(=O)N1c1c3c(cc4c1cco4)[nH]cc3)cccc2 +O=C1c2c(C(=O)N1c1ncc3c4c(cccc4)[nH]c3c1)cccc2 +O=C1c2c(C(=O)N1c1nc3oc4c(c3cc1)cccc4)cccc2 +O=C1c2c(C(=O)N1c1ccc3c(c4c5c(cccc5)[nH]c4[nH]3)c1)cccc2 +O=C1c2c(C(=O)N1c1c3c4c(cccc4)cnc3ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3c(oc4ncccc34)ccc1)cccc2 +O=C1c2c(C(=O)N1c1c3c(ccc1)[nH]c1c3ccnc1)cccc2 +O=C1c2c(C(=O)N1c1nc3c4c(c5c(c3nc1)cccc5)cccc4)cccc2 +O=C1c2c(C(=O)N1c1c3c4c(cccc4)[nH]c3cnc1)cccc2 +O=C1c2c(C(=O)N1n1c3c(c(=O)c4c1cccc4)cccc3)cccc2 +O=C1c2c(C(=O)N1n1c3c(c4c1ccnc4)cncc3)cccc2 +O=c1c2ccccc2n(-c2c3ccoc3cc3ccoc23)c2ccccc12 +O=c1c2ccccc2n(-c2cc(F)ccc2-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3)n2)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3c(c2)B2c4ccccc4Oc4cccc(c42)O3)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3c(c2)Oc2cccc4c2B3c2ccccc2O4)c2ccccc12 +O=c1c2ccccc2n(-c2ccc3ccsc3c2)c2ccccc12 +O=c1c2ccccc2n(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)c2ccccc12 +O=c1c2ccccc2n(-c2cccc3c2[nH]c2ncccc23)c2ccccc12 +O=c1c2ccccc2n(-c2ccnc3c2ccc2cccnc23)c2ccccc12 +O=c1c2ccccc2n(-c2cncc3cc[nH]c23)c2ccccc12 +O=c1c2ccccc2n(-c2cncc3[nH]c4ccccc4c23)c2ccccc12 +O=c1c2ccccc2n(-c2c[nH]c3ccncc23)c2ccccc12 +O=c1c2ccccc2n(-c2nccs2)c2ccccc12 +O=c1c2ccccc2n(-n2c3ccccc3c3cccnc32)c2ccccc12 +O=c1c2ccccc2n(-n2c3ccccc3c3ccncc32)c2ccccc12 +O=c1c2ccccc2n(-n2cnc3cc4nc[nH]c4cc32)c2ccccc12 +O=c1c2ccccc2[nH]c2c(-c3c(F)c(F)c(F)c(F)c3F)cccc12 +O=c1c2ccccc2[nH]c2c(-c3c4[nH]cnc4cc4nc[nH]c34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cc4nc5ccoc5nc4[nH]3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc(-c4ccccn4)n3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cccc4c3[nH]c3cnccc34)cccc12 +O=c1c2ccccc2[nH]c2c(-c3ccnc(-c4ccccn4)c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cnc4[nH]c5ccccc5c4c3)cccc12 +O=c1c2ccccc2[nH]c2c(-c3cncs3)cccc12 +O=c1c2ccccc2[nH]c2c(-n3nnc4ccccc43)cccc12 +O=c1c2ccccc2[nH]c2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cc4cccnc4c4ncccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc(-c4cnccn4)cc3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(c3)-c3ccccc3-s-4(=O)=O)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(cnc5ccccc54)c3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4c(n3)[nH]c3ccccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3ccc4[nH]c5cnccc5c4c3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cccc4c3-s(=O)(=O)-c3ccccc3-4)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3cccc4ocnc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3csc4ccccc34)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4cc5ncoc5nc4o3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4ccccc4o3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nc4nc5nc[nH]c5cc4[nH]3)ccc12 +O=c1c2ccccc2[nH]c2cc(-c3nccs3)ccc12 +O=c1c2ccccc2[nH]c2cc(-n3cnc4nc5nc[nH]c5nc43)ccc12 +O=c1c2ccccc2[nH]c2ccc(-c3c4ccoc4cc4ccoc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cc(F)ccc3-c3nc(-c4ccccc4)nc(-c4ccc(F)cc4)n3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cc4c(cn3)[nH]c3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc(-c4ccccn4)nc3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4ccsc4c3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc4[nH]nnc4c3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4c(=O)cc[nH]c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4c3ncc3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4ccsc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cccc4ncc5ccccc5c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccnc4c3ccc3cccnc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccnc4[nH]c5ccccc5c34)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3cnc(-c4ccccc4)cn3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3nc4nc5ocnc5nc4o3)cc12 +O=c1c2ccccc2[nH]c2ccc(-c3nccc4c3[nH]c3ccccc34)cc12 +O=c1c2ccccc2[nH]c2ccc(-n3ccc4cnccc43)cc12 +O=c1c2ccccc2[nH]c2cccc(-c3cc4cccnc4c4ncccc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4ccsc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4ncoc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4nn[nH]c4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccc4sc5ccccc5c4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cccc4c3-c3ccccc3-s-4(=O)=O)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cccc4ncc5ccccc5c34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ccnc4cccnc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cnc4c(ccc5cccnc54)c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cnc4ncccc4c3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3cncs3)c12 +O=c1c2ccccc2[nH]c2cccc(-c3nccc4[nH]ccc34)c12 +O=c1c2ccccc2[nH]c2cccc(-c3ncno3)c12 +O=c1c2ccccc2[nH]c2cccc(-n3c4ccccc4c4ccncc43)c12 +O=C1c2c(C(=O)C(=C1)N1c3c(Sc4c1cccc4)cccc3)cccc2 +O=C1c=c(-c2c3ccoc3cc3ccoc23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(cc3c1cco3)[nH]cc2 +O=C1C=C(C(=O)N1)c1c2c(ocn2)cc2ncoc12 +O=C1C=C(C(=O)N1)c1cc(=O)c2c(cccc2)[nH]1 +O=C1c=c(-c2cc3c(cn2)[nH]c2ccccc23)C(=O)c2ccccc21 +O=C1c=c(-c2cc3cc4occc4cc3o2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1oc2c(c1)cccc2 +O=C1C=C(C(=O)N1)c1ncc2c(c1)[nH]c1c2cncc1 +O=C1C=C(C(=O)N1)c1ccc(N(c2ccccc2)c2ccccc2)cc1 +O=C1C=C(C(=O)N1)c1ccc2CCc3c(cccc3)Nc2c1 +O=C1c2c(C(=O)C(=C1)c1ccc3CCc4c(cccc4)Nc3c1)cccc2 +O=C1c2c(C(=O)C(=C1)c1ccc3c(Sc4c(cccc4)N3)c1)cccc2 +O=C1C=C(C(=O)N1)c1ccc2c(oc3ncccc23)c1 +O=C1C=C(C(=O)N1)c1cc2c(c3c4c(c5c(cccc5)[nH]4)ccc3[nH]2)cc1 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]c1c2cncc1 +O=C1c=c(-c2ccc3c4c2CCCN4CCC3)C(=O)c2ccccc21 +O=C1c=c(-c2ccc3c4ccccc4c4nccnc4c3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c3c(c4c(nc[nH]4)c2c1)cccc3 +O=C1C=C(C(=O)N1)c1ccc2c(scc2)c1 +O=C1c=c(-c2ccc3ccsc3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]cc2 +O=C1c=c(-c2ccc3ncsc3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1ccc2c(c1)[nH]nn2 +O=C1C=C(C(=O)N1)c1cc2c(occ2)cc1 +O=C1c=c(-c2ccc3[nH]c4c(ccc5[nH]c6ccccc6c54)c3c2)C(=O)c2ccccc21 +O=C1c=c(-c2ccc3[nH]nnc3c2)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3c2cnc2ccccc23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(c3c4c(cccc4)[nH]c3[nH]2)ccc1 +O=C1c=c(-c2cccc3c4ccccc4c4nc[nH]c4c23)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3c4ccccc4c4[nH]cnc4c23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(nn[nH]2)ccc1 +O=C1c=c(-c2cccc3ocnc23)C(=O)c2ccccc21 +O=C1c=c(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c(c2cc3c4c(CCCN4CCC3)c2)cccc1 +O=C1c=c(-c2cnc3sc4ccccc4c3c2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c3c(cccc3)[nH]c2cnc1 +O=C1c=c(-c2c[nH]c(=O)[nH]2)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)c1c2c(cccc2)[nH]c1 +O=C1c=c(-c2nc3cc4ocnc4cc3o2)C(=O)c2ccccc21 +O=C1c=c(-n2c3ccccc3c(=O)c3ccccc32)C(=O)c2ccccc21 +O=C1C=C(C(=O)N1)n1c2c(c3c1ccnc3)cccc2 +O=C1C=C(C(=O)N1)n1c2c(nc1)c1c(c3c2cccc3)cccc1 +O=C1C=CC(=O)N1c1c2c(c3c(c4c(cccc4)[nH]3)c1)c1c(cccc1)[nH]2 +O=C1C=CC(=O)N1c1sc2c(c1)cccc2 +O=C1C=CC(=O)N1c1cc2c(cccc2)[nH]1 +O=C1C=CC(=O)N1c1oc2c(nc3c(n2)[nH]cc3)c1 +O=C1C=CC(=O)N1c1c2c3c(cccc3)[nH]c2c2c(c1)[nH]c1c2cccc1 +O=C1C=CC(=O)N1c1ncc2c(c1)[nH]c1c2cncc1 +O=C1C=CC(=O)N1c1ccc(c2cc3c4c(CCCN4CCC3)c2)cc1 +O=C1C=CC(=O)N1c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1C=CC(=O)N1c1cc2c(c3c4c(cccc4)[nH]c3[nH]2)cc1 +O=C1C=CC(=O)N1c1ccc2c3c(c4c(c2c1)nccn4)cccc3 +O=C1C=CC(=O)N1c1cc2c(occ2)cc1 +O=C1C=CC(=O)N1c1cc2ncsc2cc1 +O=C1C=CC(=O)N1c1c2ncc3c(c2ccc1)cccc3 +O=C1C=CC(=O)N1c1c2c(c3c(c4c(cc3)[nH]c3c4cccc3)[nH]2)ccc1 +O=C1C=CC(=O)N1c1c2c(nco2)ccc1 +O=C1C=CC(=O)N1c1c2c3c(cccc3)[nH]c2cnc1 +O=C1C=CC(=O)N1c1c2c(oc1)cc1c(occ1)c2 +O=C1C=CC(=O)N1c1c2c(oc1)cccc2 +O=C1C=CC(=O)N1c1c2c(cc3c(c2)cco3)[nH]c1 +O=C1C=CC(=O)N1c1c2c(c3c(n1)cccc3)cccc2 +O=C1C=CC(=O)N1n1c2c(c3c1ccnc3)cccc2 +O=C1C=CC(=O)N1n1c2c(nc3c(occ3)n2)cc1 +O=C1C=CC(=O)N1n1c2c(nn1)cccc2 +O=C1c2c(C(=O)C=C1)cccc2N1c2c(CCc3c1cccc3)cccc2 +O=C1c=cC(=O)c2c1cccc2-c1c2ncoc2cc2ncoc12 +O=C1c=cC(=O)c2c1cccc2-c1c2[nH]ccc2cc2ccoc12 +O=C1c=cC(=O)c2c1cccc2-c1cc2nc3ccoc3nc2[nH]1 +O=C1c=cC(=O)c2c1cccc2-c1ccc(F)c(F)c1F +O=C1c2c(C(=O)C=C1)cccc2c1ccc2c(Sc3c(cccc3)N2)c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2c(c1)ncc1ccccc12 +O=C1c=cC(=O)c2c1cccc2-c1ccc2c(n1)sc1ncccc12 +O=C1c=cC(=O)c2c1cccc2-c1ccc2cnc3ccccc3c2c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2ncc3ccccc3c2c1 +O=C1c=cC(=O)c2c1cccc2-c1ccc2[nH]c3[nH]c4ccccc4c3c2c1 +O=C1c2c(C(=O)C=C1)cccc2c1c2c(Sc3c(cccc3)N2)ccc1 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c1[nH]c1c2ccc2[nH]c3ccccc3c21 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c1[nH]c1cnccc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2c3ccccc3c3nccnc3c12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2ccoc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2occc12 +O=C1c=cC(=O)c2c1cccc2-c1cccc2[nH]c3ccccc3c(=O)c12 +O=C1c=cC(=O)c2c1cccc2-c1ccccc1N(c1ccccc1)c1ccccc1 +O=C1c=cC(=O)c2c1cccc2-c1nc2c3ccccc3c3ccccc3c2[nH]1 +O=C1c=cC(=O)c2c1cccc2-c1nccc2[nH]c3ccncc3c12 +O=C1c=cC(=O)c2c1cccc2-n1c2ccncc2c2cnccc21 +O=C1c=cC(=O)c2c1cccc2-n1ccc(=O)c2ccccc21 +O=C1c=cC(=O)c2cc(-c3cc4cc5ccoc5cc4[nH]3)ccc21 +O=C1c=cC(=O)c2cc(-c3cc4cc5occc5cc4o3)ccc21 +O=C1c=cC(=O)c2cc(-c3cc4nc5cc[nH]c5nc4o3)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(=O)cc[nH]c4c3)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(c3)Oc3ccccc3O4)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(c3)sc3ncccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4c(n3)sc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccc4[nH]ccc(=O)c4c3)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3cnc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3ncc3ccccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3oc3ncccc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3[nH]c3ccncc34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4c3[nH]c3[nH]c5ccccc5c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5c(ccc6[nH]c7ccccc7c65)c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5ccccc5c(=O)c34)ccc21 +O=C1c=cC(=O)c2cc(-c3cccc4[nH]c5ccncc5c34)ccc21 +O=C1c=cC(=O)c2cc(-c3ccccc3-c3cc4c5c(c3)CCCN5CCC4)ccc21 +O=C1c=cC(=O)c2cc(-c3cnc4sc5ccccc5c4c3)ccc21 +O=C1c=cC(=O)c2cc(-n3cc[nH]c3=O)ccc21 +O=C1c=cC(=O)c2cc(-n3nnc4ccccc43)ccc21 +O=c1cc(-c2c3nc[nH]c3cc3[nH]cnc23)[nH]c2ccccc12 +O=c1cc(-c2cc3cccnc3c3ncccc23)[nH]c2ccccc12 +O=c1cc(-c2cc3[nH]c4ccncc4c3cn2)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)-s(=O)(=O)-c2ccccc2-3)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)c2ccccc2c2nccnc32)[nH]c2ccccc12 +O=c1cc(-c2ccc3c(c2)c2ccccc2c2nc[nH]c32)[nH]c2ccccc12 +O=c1c2c(cccc2)[nH]c(c1)c1cc2CCc3c(cccc3)Nc2cc1 +O=c1cc(-c2ccc3c(n2)sc2ccccc23)[nH]c2ccccc12 +O=c1cc(-c2ccc3c4c2CCCN4CCC3)[nH]c2ccccc12 +O=c1cc(-c2ccc3c4ccccc4c4nc[nH]c4c3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3cc[nH]c3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3scnc3c2)[nH]c2ccccc12 +O=c1cc(-c2ccc3[nH]c4ccncc4c3c2)[nH]c2ccccc12 +O=c1cc(-c2cccc(-c3nc(-c4ccc(F)cc4)nc(-c4ccc(F)cc4)n3)c2)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4ccccc4c4nccnc4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4ccccc4c4nc[nH]c4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3c4nccnc4c4ccccc4c23)[nH]c2ccccc12 +O=c1cc(-c2cccc3[nH]c4ccccc4c(=O)c23)[nH]c2ccccc12 +O=c1cc(-c2ccnc3c2ccc2cccnc23)[nH]c2ccccc12 +O=c1cc(-c2ccnc3cccnc23)[nH]c2ccccc12 +O=c1cc(-c2ccon2)[nH]c2ccccc12 +O=c1cc(-c2cc[nH]n2)[nH]c2ccccc12 +O=c1cc(-c2cnc3cccnc3c2)[nH]c2ccccc12 +O=c1cc(-c2c[nH]c3ccncc23)[nH]c2ccccc12 +O=c1cc(-c2nc3nc4ocnc4nc3o2)[nH]c2ccccc12 +O=c1cc(-n2c3ccccc3c3ccncc32)[nH]c2ccccc12 +O=c1cc(-n2ccc(=O)c3ccccc32)[nH]c2ccccc12 +O=c1cc(-n2cnc3nc4nc[nH]c4nc32)[nH]c2ccccc12 +O=C1c2c(C(=O)N1)cccc2c1ncc2c(c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)cccc2c1c(F)c(c(F)cc1)F +O=C1c2c(C(=O)N1)cccc2c1ccc2c(sc3ncccc23)c1 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c1)[nH]c1c2ccc2c1c1c(cccc1)[nH]2 +O=C1c2c(C(=O)N1)cccc2c1ccc2c(c(=O)c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)cccc2c1cccc(N(c2ccccc2)c2ccccc2)c1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)Nc1c(S2)cccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(c3c(c4c2nccn4)cccc3)ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c3nc[nH]c3c3c(c2ccc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1c2ncsc2ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(ccc1)[nH]c1c2cncc1 +O=C1c2c(C(=O)N1)cccc2c1c2c(=O)cc[nH]c2ccc1 +O=C1c2c(C(=O)N1)cccc2c1c2c3c(sc2ncc1)cccc3 +O=C1c2c(C(=O)N1)cccc2c1nc2c3c(c4c(c2nc1)cccc4)cccc3 +O=C1c2c(C(=O)N1)cccc2c1cnc2c(c3c(nccc3)s2)c1 +O=C1c2c(C(=O)N1)cccc2c1oc2c(n1)cc1c(nco1)c2 +O=C1c2c(C(=O)N1)cccc2n1c2c(c(=O)c3c1cccc3)cccc2 +O=C1c2c(C(=O)N1)cccc2n1c2c(c3c1c1c(cc3)[nH]c3c1cccc3)cccc2 +O=C1c2c(C(=O)N1)cccc2n1c2c(nc1)c1c(c3c2cccc3)cccc1 +O=C1c2c(C(=O)N1)cccc2n1c2c(nc1)nc1nc[nH]c1n2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc3c(c2)cco3)[nH]1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c3c(cccc3)[nH]c2c2c(c1)[nH]c1c2cccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(oc3ncccc23)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)[nH]c1c2ccc2c1c1c(cccc1)[nH]2 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(c3c4c(c5c(cccc5)[nH]4)ccc3[nH]2)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c1)cnc1c2cccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2ncoc2c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(occ2)cc1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccc2c(c(=O)c3c(cccc3)[nH]2)c1 +O=C1c2c(C(=O)N1)ccc(c2)c1cc2c(cc1)[nH]cc2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c(=O)c3c(cccc3)[nH]2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(Sc3c(cccc3)N2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(nco2)ccc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccc1)[nH]c1c2c2c(cccc2)[nH]1 +O=C1c2c(C(=O)N1)ccc(c2)c1ccnnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(c3c(cccc3)[nH]2)cnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c3c(cccc3)[nH]c2cnc1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(oc1)cc1c(cc[nH]1)c2 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(cc3c(c2)cco3)[nH]c1 +O=C1c2c(C(=O)N1)ccc(c2)c1c2c(ccn1)[nH]c1c2cncc1 +O=C1c2c(C(=O)N1)ccc(c2)n1c2c(c3c(cccc3)[nH]2)c2c1cccc2 +O=c1ccn(-c2c3ncsc3cc3ncsc23)c2ccccc12 +O=c1ccn(-c2cc3ccccc3o2)c2ccccc12 +O=c1ccn(-c2cc3cccnc3c3ncccc23)c2ccccc12 +O=c1ccn(-c2cc3[nH]ccc3cn2)c2ccccc12 +O=c1ccn(-c2ccc(F)c(F)c2F)c2ccccc12 +O=c1ccn(-c2ccc3c(c2)-c2ccccc2-s-3(=O)=O)c2ccccc12 +O=c1ccn(-c2ccc3c(c2)B2c4ccccc4Oc4cccc(c42)O3)c2ccccc12 +O=c1c2c(n(cc1)c1cc3CCc4c(cccc4)Nc3cc1)cccc2 +O=c1ccn(-c2ccc3c(c2)[nH]c2ncccc23)c2ccccc12 +O=c1ccn(-c2ccc3[nH]ccc3c2)c2ccccc12 +O=c1ccn(-c2cccc3ccsc23)c2ccccc12 +O=c1ccn(-c2cccc3cnc4ccccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3oc4ccccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3oc4ncccc4c23)c2ccccc12 +O=c1ccn(-c2cccc3ocnc23)c2ccccc12 +O=c1ccn(-c2cccc3scnc23)c2ccccc12 +O=c1ccn(-c2cccc3[nH]c4ccc5c6ccccc6[nH]c5c4c23)c2ccccc12 +O=c1ccn(-c2cccc3[nH]c4ccncc4c23)c2ccccc12 +O=c1ccn(-c2ccno2)c2ccccc12 +O=c1ccn(-c2cnc3sc4ncccc4c3c2)c2ccccc12 +O=c1ccn(-c2cncc(-c3ccccc3)n2)c2ccccc12 +O=c1ccn(-c2cncc3[nH]c4ccccc4c23)c2ccccc12 +O=c1ccn(-c2c[nH]c3cc4occc4cc23)c2ccccc12 +O=c1ccn(-c2c[nH]c3ccncc23)c2ccccc12 +O=c1cc[nH]c2c(-c3c4ccoc4cc4ccoc34)cccc12 +O=c1cc[nH]c2c(-c3c4[nH]ccc4cc4ccoc34)cccc12 +O=c1cc[nH]c2c(-c3cc4ccccc4o3)cccc12 +O=c1cc[nH]c2c(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)cccc12 +O=c1cc[nH]c2c(-c3ccc(F)c(F)c3F)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)ncc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)oc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4c(c3)[nH]c3cnccc34)cccc12 +O=c1cc[nH]c2c(-c3ccc4ccsc4c3)cccc12 +O=c1cc[nH]c2c(-c3ccc4sccc4c3)cccc12 +O=c1cc[nH]c2c(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)cccc12 +O=c1cc[nH]c2c(-c3cccc4c3oc3ccccc34)cccc12 +O=c1cc[nH]c2c(-c3cccc4ncoc34)cccc12 +O=c1cc[nH]c2c(-c3cccc4nn[nH]c34)cccc12 +O=c1cc[nH]c2c(-c3cccc4oc5ccccc5c34)cccc12 +O=c1cc[nH]c2c(-c3cccc4[nH]c5ccc6c7ccccc7[nH]c6c5c34)cccc12 +O=c1cc[nH]c2c(-c3ccccc3-c3cnccn3)cccc12 +O=c1cc[nH]c2c(-c3ccnc4cccnc34)cccc12 +O=c1cc[nH]c2c(-c3ccnc4sc5ccccc5c34)cccc12 +O=c1cc[nH]c2c(-c3cnc4c5ccccc5c5ccccc5c4n3)cccc12 +O=c1cc[nH]c2c(-c3cnc4ncccc4c3)cccc12 +O=c1cc[nH]c2c(-c3cnc4nccnc4n3)cccc12 +O=c1cc[nH]c2c(-c3cscn3)cccc12 +O=c1cc[nH]c2c(-c3c[nH]c4ccncc34)cccc12 +O=c1cc[nH]c2c(-c3nc4nc5nc[nH]c5cc4[nH]3)cccc12 +O=c1cc[nH]c2c(-n3c4ccccc4c4ccncc43)cccc12 +O=c1cc[nH]c2c(-n3ccc4ccccc43)cccc12 +O=c1cc[nH]c2cc(-c3c(-c4ccccc4)cc4c5c3CCCN5CCC4)ccc12 +O=c1cc[nH]c2cc(-c3c4ncoc4cc4ncoc34)ccc12 +O=c1cc[nH]c2cc(-c3c4ncsc4cc4ncsc34)ccc12 +O=c1cc[nH]c2cc(-c3c4nc[nH]c4cc4[nH]cnc34)ccc12 +O=c1cc[nH]c2cc(-c3c4[nH]cnc4cc4nc[nH]c34)ccc12 +O=c1cc[nH]c2cc(-c3cc4c5ccccc5[nH]c4c4c3[nH]c3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3cc4cc5cc[nH]c5cc4o3)ccc12 +O=c1cc[nH]c2cc(-c3cc4ccccc4o3)ccc12 +O=c1cc[nH]c2cc(-c3cc4ccccc4s3)ccc12 +O=c1cc[nH]c2cc(-c3cc4nc5ccoc5nc4[nH]3)ccc12 +O=c1cc[nH]c2cc(-c3ccc(-c4ccccn4)nc3)ccc12 +O=c1cc[nH]c2cc(-c3ccc(-c4nc(-c5ccc(F)cc5)nc(-c5ccc(F)cc5)n4)cc3)ccc12 +O=c1c2c(cc(cc2)c2ccc3CCc4c(cccc4)Nc3c2)[nH]cc1 +O=c1cc[nH]c2cc(-c3ccc4c(c3)-s(=O)(=O)-c3ccccc3-4)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)Oc3ccccc3O4)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)sc3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(c3)[nH]c3[nH]c5ccccc5c34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4c(n3)sc3ccccc34)ccc12 +O=c1cc[nH]c2cc(-c3ccc4ncsc4c3)ccc12 +O=c1cc[nH]c2cc(-c3ccc4[nH]c5[nH]c6ccccc6c5c4c3)ccc12 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)-[nH]-c4ccccc4CC5)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)c4ccccc4c4[nH]cnc54)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)[nH]c4ccc6c7ccccc7[nH]c6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5cc[nH]c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5[nH]c6ccc7c8ccccc8[nH]c7c6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4cnc4ccccc45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4[nH]c4cnccc45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c6nc[nH]c6c6ccccc6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cnc5oc6ccccc6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cnc5sc6ccccc6c5c4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5cc6ocnc6cc5o4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5cc6scnc6cc5s4)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nccc5[nH]c6ccccc6c45)cc3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5cc6occc6cc5o4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5ccccc5o4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cc5[nH]c6ccccc6c5c5[nH]c6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5sc6ncccc6c5c4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c4-[nH]-c4ccccc4CC5)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c6ccccc6c6nccnc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5cnc6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5oc6ccccc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5occc45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5[nH]c6ccncc6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5[nH]c6[nH]c7ccccc7c6c45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4c[nH]c5cc6occc6cc45)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4nc5nc6nc[nH]c6nc5[nH]4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4ccc5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4nnc5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cc4nc5ccoc5nc4[nH]3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cc4nc5cc[nH]c5nc4o3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)-s-c3ccccc3-[nH]-4)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)-[nH]-c3ccccc3-s-4)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)c3ccccc3c3nc[nH]c43)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c(c3)[nH]c3cnccc34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4c5ccccc5c5nc[nH]c5c4c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccc4sc5ncccc5c4c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cccc(N(c4ccccc4)c4ccccc4)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3cccc4c5[nH]cnc5c5ccccc5c34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3c[nH]c4cc5occc5cc34)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3c4ccccc4c4ccc5[nH]c6ccccc6c5c43)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-n3cnc4nc5nc[nH]c5nc43)n2)cc1 +CC1(C)c2cc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)ccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccccc1 +CC1(C)c2cc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)ccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4)c3cc21 +CC1(C)c2cc3c(cc2-[nH]-c2c(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)cccc21)c1ccccc1n3-c1ccccc1 +CC1(C)c2cc3c(cc2-[nH]-c2cccc(-c4ccc5cccc6c5c4-c4nc5cc(C#N)c(C#N)cc5nc4-6)c21)c1ccccc1n3-c1ccccc1 +CC1(C)c2ccccc2-c2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc21 +CC1(C)c2ccccc2-c2cc(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)ccc21 +CC1(C)c2ccccc2-c2ccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cc21 +CC1(C)c2ccccc2-c2ccc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc21 +CC1(C)c2ccccc2-n(-c2cc3c4c(cccc4c2)-c2nc4cc(C#N)c(C#N)cc4nc2-3)-c2cc3c4ccccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-n(-c2ccc3cccc4c3c2-c2nc3cc(C#N)c(C#N)cc3nc2-4)-c2ccccc21 +CC1(C)c2ccccc2-[nH]-c2c(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)cccc21 +CC1(C)c2ccccc2-[nH]-c2c(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cccc21 +CC1(C)c2ccccc2-[nH]-c2c1cc1c(c2-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2ccccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2c(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)cccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2c(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2cc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)ccc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc2n1-c1ccccc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccc(-c2ccc3c4c(cccc24)-c2nc4cc(C#N)c(C#N)cc4nc2-3)cc1 +CC1(C)c2ccccc2-[nH]-c2c1ccc1c2c2ccccc2n1-c1ccc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 +CC1(C)c2ccccc2-[nH]-c2cc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)ccc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4c(-c5cc6c7c(cccc7c5)-c5nc7cc(C#N)c(C#N)cc7nc5-6)cccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4c(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)cccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4cc(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)ccc4n(-c4ccccc4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4cccc(-c5c(C#N)c(C#N)cc6nc7c(nc56)-c5cccc6cccc-7c56)c4)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4-c4cc5c6c(cccc6c4)-c4nc6cc(C#N)c(C#N)cc6nc4-5)c3cc21 +CC1(C)c2ccccc2-[nH]-c2cc3c4ccccc4n(-c4ccccc4-c4ccc5cccc6c5c4-c4nc5cc(C#N)c(C#N)cc5nc4-6)c3cc21 +CC1(C)c2ccccc2-[nH]-c2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc21 +Cc1-c2ccccc2-[nH]-c2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc2-1 +Cc1-c2ccccc2-[nH]-c2cccc(-c3c(C#N)c(C#N)cc4nc5c(nc34)-c3cccc4cccc-5c34)c2-1 +Cc1c(C)c(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2c(c1C)c1ccccc1n2C +Cc1cc2c(c(C)c1C)c1c(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cccc1n2C +Cc1cccc2c1[nH]c1c(C)cc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc12 +Cc1cccc2c3cccc(C)c3n(-c3ccc4c5c(cccc35)-c3nc5cc(C#N)c(C#N)cc5nc3-4)c12 +CN(C)c1cc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc2ccccc12 +CN(C)c1cc2ccccc2cc1-c1ccc2c3c(cccc13)-c1nc3cc(C#N)c(C#N)cc3nc1-2 +CN(C)c1cc2ccccc2cc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c1 +CN(C)c1cc2ccccc2cc1-c1ccccc1-c1nc(-c2ccccc2)nc(-c2ccccc2)n1 +CN(C)c1ccc2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc2c1 +CN1c2ccccc2N(C)c2c(-c3ccc4c5c(cccc35)-c3nc5cc(C#N)c(C#N)cc5nc3-4)cccc21 +CN1c2ccccc2N(C)c2cc(-c3cc4c5c(cccc5c3)-c3nc5cc(C#N)c(C#N)cc5nc3-4)ccc21 +CN1c2ccccc2Oc2cc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)ccc21 +CN1c2ccccc2Oc2ccc(-c3ccc4cccc5c4c3-c3nc4cc(C#N)c(C#N)cc4nc3-5)cc21 +N#Cc1cc2nc3c(nc2c(-c2c(-c4ccccc4)cc4c5c2CCCN5CCC4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cc4nc5cc[nH]c5nc4o2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c(c2)[nH]c2ccc5c6ccccc6[nH]c5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c(c2)[nH]c2ccncc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4c5c2CCCN5CCC4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4ccoc4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4ocnc4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2ccc4[nH]c5[nH]c6ccccc6c5c4c2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c(=O)cc[nH]c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2ncc2ccccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2[nH]c2cnccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4c5ccccc5c5nc[nH]c5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4cnc5ccccc5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4occc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4[nH]c5ccccc5c(=O)c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2cccc4[nH]ccc(=O)c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2nccc4c2[nH]c2ccccc24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-c2nccc4[nH]c5ccncc5c24)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2-c4ccccc4CCc4ccccc4-2)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2ccc(=O)c4ccccc42)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2c(-n2ccc4nc5ccoc5nc42)c1C#N)-c1cccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4c5ccccc5[nH]c4c4c2[nH]c2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4ccccc4o2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cc4nc5ccoc5nc4[nH]2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc(N)cc2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)CCc2ccccc2-[nH]-4)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)oc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(c2)[nH]c2ccncc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(n2)oc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4c(n2)sc2ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4ccoc4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4occc4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c(=O)cc[nH]c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c5ccccc5c5nc[nH]c5c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4c5nccnc5c5ccccc5c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4ccsc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2cccc4[nH]ccc(=O)c24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2coc4ccccc24)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-c2c[nH]c(=O)[nH]2)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-n2c4ccccc4c4c5ccccc5[nH]c42)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1c(-n2cc[nH]c2=O)ccc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cc(F)c(F)c(F)c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cc4nc5cc[nH]c5nc4o2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4c(c2)CCc2ccccc2-[nH]-4)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4ocnc4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4[nH]c5ccc6c7ccccc7[nH]c6c5c4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2ccc4[nH]ccc(=O)c4c2)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4c2cnc2ccccc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4c2Oc2ccccc2O4)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4ncsc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-c2cccc4sccc24)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-n2c4ccccc4c4ccc5[nH]c6ccccc6c5c42)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1cc(-n2ccc4nc5ccoc5nc42)cc2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2c4ccoc4cc4ccoc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cc4cc5cc[nH]c5cc4o2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)c2ccccc2c2nc[nH]c42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)c2ccccc2c2[nH]cnc42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(c2)[nH]c2cnccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4c(n2)sc2ncccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4oc5ccccc5c4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4ocnc4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccc4[nH]c5[nH]c6ccccc6c5c4c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc(N(c4ccccc4)c4ccccc4)c2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c(=O)cc[nH]c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c2[nH]c2c4ccc4[nH]c5ccccc5c42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4c2[nH]c2cnccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4oc5ccccc5c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cccc4scnc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccnc4sc5ncccc5c24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2ccnnc2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2cncc4c2[nH]c2ccccc24)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2nc4cc5scnc5cc4s2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-c2nc4ccccc4s2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2-c4ccccc4-s-c4ccccc4-2)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2ccc4cc5ccoc5cc42)c2cccc-3c12 +N#Cc1cc2nc3c(nc2cc1C#N)-c1ccc(-n2cnc4c5ccccc5c5ccccc5c42)c2cccc-3c12 +O=c1c2ccccc2n(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2ccccc12 +O=c1c2ccccc2[nH]c2c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc12 +O=c1c2ccccc2[nH]c2ccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc12 +O=c1ccn(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2ccccc12 +c1ccc(-c2cncc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +c1ccc(-c2cncc(-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccccc4C4(c5ccccc5)c5ccccc5-[nH]-c5ccccc54)c3)n2)cc1 +c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)n2)cc1 +c1ccc(-c2nccnc2-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1 +c1ccc(-c2nccnc2-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cc5cc6occc6cc5o4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cc5[nH]ccc5cn4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccc5c(c4)Oc4cccc6c4B5c4ccccc4O6)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccnc5c4ccc4cccnc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4ccnc5[nH]c6ccccc6c45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cnc5nccnc5n4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4cncc5[nH]c6ccccc6c45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4csc5ccccc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4c[nH]c5nc6occc6nc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4nc5ccccc5c5ccccc45)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccc(-c4nc5nc6nc[nH]c6nc5[nH]4)cc3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4c5[nH]cnc5nc5nc[nH]c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cc5c(cn4)[nH]c4ccccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cc5cc6occc6cc5o4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5c(c4)sc4ccccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5ncccc5n4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccc5sc6ccccc6c5c4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccc5c4[nH]c4ncccc45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccc5sc6ccccc6c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cccnc4-c4ccccn4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4ccnc5[nH]c6ccccc6c45)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cnc5nccnc5n4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-c4cnoc4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3cccc(-n4nnc5ccccc54)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ccc4c(c3)Oc3cccc5c3B4c3ccccc3O5)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ncno3)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-n(-c3ncon3)-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cc5nc6cc[nH]c6nc5o4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cc5[nH]ccc5cn4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccc5ncoc5c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccc5[nH]c6cnccc6c5c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cccc(-c5cnccn5)c4)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cccc5nn[nH]c45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4ccnc5c4ccc4cccnc45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-c4cncc5c4[nH]c4ccncc45)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4c5ccccc5c5cccnc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4ccc5nc6ccoc6nc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3c(-n4cnc5cc6nc[nH]c6cc54)cccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4c5[nH]cnc5cc5nc[nH]c45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cc5nc6ccoc6nc5[nH]4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cccc(-c5cnccn5)c4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cccc5c4[nH]c4ncccc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccccc4-c4cnccn4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccnc5[nH]c6ccccc6c45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4ccon4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4cncs4)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4coc5cc6ccoc6cc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-c4coc5nc6[nH]ccc6nc45)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cc(-n4cnc5nc6nc[nH]c6nc54)ccc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4c5[nH]cnc5cc5nc[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4c5[nH]cnc5nc5nc[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cc5ccccc5s4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc(-c5cnccn5)cc4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5ccc6cccnc6c5n4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5nn[nH]c5c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4ccc5[nH]nnc5c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc(-c5cnccn5)c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5c4Oc4cccc6c4B5c4ccccc4O6)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5c4[nH]c4ncccc45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5nn[nH]c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5[nH]c6ncccc6c45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cccc5[nH]nnc45)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cnc5c(ccc6cccnc65)c4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccc(-c4cnc5ccccc5n4)cc32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5c6c4Oc4ccccc4B6c4ccccc4O5)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5ccsc5c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccc5[nH]nnc5c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc(-c5cnccn5)c4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5c4cnc4ccccc45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5c4sc4ccccc45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cccc5[nH]c6cnccc6c45)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4ccno4)c32)cc1 +c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3cccc(-c4cnc5c(ccc6cccnc65)c4)c32)cc1 +c1ccc(C2(c3ccccc3-c3cc4cnccc4[nH]3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4cccnc4n3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccc4nn[nH]c4c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3cccc4sc5ccccc5c34)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3ccnc(-c4ccccn4)c3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nc4cc5ncoc5nc4o3)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nc4ccccc4c4ccccc34)c3ccccc3-[nH]-c3ccccc32)cc1 +c1ccc(C2(c3ccccc3-c3nccs3)c3ccccc3-[nH]-c3ccccc32)cc1 +CC(=O)c1cccc(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)c1 +CC(=O)c1ccccc1-c1cccc2c1-[nH]-c1ccccc1C2(c1ccccc1)c1ccccc1 +Cc1-c2ccccc2-c2cc(-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)ccc2-1 +Cc1-c2ccccc2-c2cc(-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)ccc2-1 +Cc1-c2ccccc2-c2ccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cc2-1 +Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccccc3-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +Fc1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(F)cc3-n3-c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc4-3)n2)cc1 +N#Cc1cc(C#N)c(-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c(C#N)c1 +N#Cc1cc2nc3c(nc2c(-c2cccc4c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-4)c1C#N)-c1cccc2cccc-3c12 +N#Cc1ccc(-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1 +N#Cc1ccc(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)c(C#N)c1C#N +N#Cc1cccc(-c2ccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cc2)c1 +N#Cc1cccc(C#N)c1-c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1 +N#Cc1ccccc1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-[nH]-2 +N#Cc1cnc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)nc1 +O=C(c1ccc(-c2ccc3c(c2)-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1 +O=C(c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3)n2)cc1)c1cccc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1 +O=C(c1cccc(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c1)C(F)(F)F +O=C(c1cccc(-c2cccc3c2-[nH]-c2ccccc2C3(c2ccccc2)c2ccccc2)c1)C(F)(F)F +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-[nH]-5)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)c(-c4cccc5c4-[nH]-c4ccccc4C5(c4ccccc4)c4ccccc4)c3)n2)cc1 +O=C(c1ccccc1)c1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(F)cc3-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)n2)cc1 +O=C(c1ccccc1-c1ccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)cc1)C(F)(F)F +O=C(c1ccccc1-c1cccc2c1-[nH]-c1ccccc1C2(c1ccccc1)c1ccccc1)C(F)(F)F +O=C(c1ccccc1-n1-c2ccccc2C(c2ccccc2)(c2ccccc2)c2ccccc2-1)C(F)(F)F +O=c1c(-c2ccccc2C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c[nH]c2ccccc12 +O=C1c2ccccc2C(=O)n1-c1cccc(C2(c3ccccc3)c3ccccc3-[nH]-c3ccccc32)c1 +O=C1c2ccccc2C(=O)n1-c1cccc2c1C(c1ccccc1)(c1ccccc1)c1ccccc1-[nH]-2 +O=C1c=c(-c2ccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cc2)C(=O)[nH]1 +O=C1c=c(-n2-c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc3-2)C(=O)[nH]1 +O=c1cc(-c2cccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)c2)[nH]c2ccccc12 +O=c1cc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)[nH]c2ccccc12 +O=c1ccn(-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c2ccccc12 +O=c1ccn(-c2cccc(C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)c2)c2ccccc12 +O=c1ccn(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2-[nH]-3)c2ccccc12 +O=c1cc[nH]c2c(-c3cccc4c3C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)cccc12 +O=c1cc[nH]c2c(-c3ccccc3C3(c4ccccc4)c4ccccc4-[nH]-c4ccccc43)cccc12 +O=C1[nH]C(=O)c2cc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)ccc21 +O=s1(=O)-c2ccccc2-c2c(-c3cccc4c3-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cccc2-1 +O=s1(=O)-c2ccccc2-c2cc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)ccc2-1 +O=s1(=O)-c2ccccc2-c2ccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)cc2-1 +O=s1(=O)-c2ccccc2-c2cccc(-c3ccc4c(c3)-[nH]-c3ccccc3C4(c3ccccc3)c3ccccc3)c2-1 +O=s1(=O)-c2ccccc2-c2cccc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-[nH]-4)c2-1 diff --git a/examples/tadf/requirements.txt b/examples/tadf/requirements.txt new file mode 100644 index 000000000..180e2a38c --- /dev/null +++ b/examples/tadf/requirements.txt @@ -0,0 +1,2 @@ +rdkit +scikit-learn diff --git a/mkdocs.yml b/mkdocs.yml index 2e70c8092..b363c83d4 100644 --- a/mkdocs.yml +++ b/mkdocs.yml @@ -113,6 +113,7 @@ nav: - 化学科学(AI for Chemistry): - Moflow: zh/examples/moflow.md - IFM: zh/examples/ifm.md + - TADF: zh/examples/tadf.md - API 文档: - ppsci: diff --git a/ppsci/arch/__init__.py b/ppsci/arch/__init__.py index ec3f63597..4dd2023ad 100644 --- a/ppsci/arch/__init__.py +++ b/ppsci/arch/__init__.py @@ -59,6 +59,7 @@ from ppsci.arch.velocitygan import VelocityGenerator # isort:skip from ppsci.arch.moflow_net import MoFlowNet, MoFlowProp # isort:skip from ppsci.utils import logger # isort:skip +from ppsci.arch.tadf import TADF # isort:skip from ppsci.arch.regdgcnn import RegDGCNN # isort:skip from ppsci.arch.regpointnet import RegPointNet # isort:skip from ppsci.arch.ifm_mlp import IFMMLP # isort:skip @@ -101,6 +102,7 @@ "RosslerEmbedding", "SFNONet", "SPINN", + "TADF", "TFNO1dNet", "TFNO2dNet", "TFNO3dNet", diff --git a/ppsci/arch/new_model.py b/ppsci/arch/new_model.py new file mode 100644 index 000000000..5555424f3 --- /dev/null +++ b/ppsci/arch/new_model.py @@ -0,0 +1,249 @@ +from typing import Dict +from typing import Optional +from typing import Tuple +from typing import Union + +import numpy as np +import paddle +import paddle.nn as nn + +from ppsci.arch import activation as act_mod +from ppsci.arch import base +from ppsci.utils import initializer + + +class WeightNormLinear(nn.Layer): + def __init__(self, in_features: int, out_features: int, bias: bool = True) -> None: + super().__init__() + self.in_features = in_features + self.out_features = out_features + self.weight_v = self.create_parameter((in_features, out_features)) + self.weight_g = self.create_parameter((out_features,)) + if bias: + self.bias = self.create_parameter((out_features,)) + else: + self.bias = None + self._init_weights() + + def _init_weights(self) -> None: + initializer.xavier_uniform_(self.weight_v) + initializer.constant_(self.weight_g, 1.0) + if self.bias is not None: + initializer.constant_(self.bias, 0.0) + + def forward(self, input): + norm = self.weight_v.norm(p=2, axis=0, keepdim=True) + weight = self.weight_g * self.weight_v / norm + return nn.functional.linear(input, weight, self.bias) + + +class RandomWeightFactorization(nn.Layer): + def __init__( + self, + in_features: int, + out_features: int, + bias: bool = True, + mean: float = 0.5, + std: float = 0.1, + ): + super().__init__() + self.in_features = in_features + self.out_features = out_features + self.weight_v = self.create_parameter((in_features, out_features)) + self.weight_g = self.create_parameter((out_features,)) + if bias: + self.bias = self.create_parameter((out_features,)) + else: + self.bias = None + + self._init_weights(mean, std) + + def _init_weights(self, mean, std): + with paddle.no_grad(): + initializer.glorot_normal_(self.weight_v) + + nn.initializer.Normal(mean, std)(self.weight_g) + paddle.assign(paddle.exp(self.weight_g), self.weight_g) + paddle.assign(self.weight_v / self.weight_g, self.weight_v) + if self.bias is not None: + initializer.constant_(self.bias, 0.0) + + self.weight_g.stop_gradient = False + self.weight_v.stop_gradient = False + self.bias.stop_gradient = False + + def forward(self, input): + return nn.functional.linear(input, self.weight_g * self.weight_v, self.bias) + + +class PeriodEmbedding(nn.Layer): + def __init__(self, periods: Dict[str, Tuple[float, bool]]): + super().__init__() + self.freqs_dict = { + k: self.create_parameter( + [], + attr=paddle.ParamAttr(trainable=trainable), + default_initializer=nn.initializer.Constant(2 * np.pi / float(p)), + ) # mu = 2*pi / period for sin/cos function + for k, (p, trainable) in periods.items() + } + self.freqs = nn.ParameterList(list(self.freqs_dict.values())) + + def forward(self, x: Dict[str, paddle.Tensor]): + y = {k: v for k, v in x.items()} # shallow copy to avoid modifying input dict + + for k, w in self.freqs_dict.items(): + y[k] = paddle.concat([paddle.cos(w * x[k]), paddle.sin(w * x[k])], axis=-1) + + return y + + +class FourierEmbedding(nn.Layer): + def __init__(self, in_features, out_features, scale): + super().__init__() + if out_features % 2 != 0: + raise ValueError(f"out_features must be even, but got {out_features}.") + + self.kernel = self.create_parameter( + [in_features, out_features // 2], + default_initializer=nn.initializer.Normal(std=scale), + ) + + def forward(self, x: paddle.Tensor): + y = paddle.concat( + [ + paddle.cos(x @ self.kernel), + paddle.sin(x @ self.kernel), + ], + axis=-1, + ) + return y + + +class DNN(base.Arch): + def __init__( + self, + input_keys: Tuple[str, ...], + output_keys: Tuple[str, ...], + num_layers: int, + hidden_size: Union[int, Tuple[int, ...]], + activation: str = "tanh", + skip_connection: bool = False, + weight_norm: bool = False, + input_dim: Optional[int] = None, + output_dim: Optional[int] = None, + periods: Optional[Dict[int, Tuple[float, bool]]] = None, + fourier: Optional[Dict[str, Union[float, int]]] = None, + random_weight: Optional[Dict[str, float]] = None, + dropout: Optional[float] = 0.5, + ): + super().__init__() + self.input_keys = input_keys + self.output_keys = output_keys + self.linears = [] + self.acts = [] + self.periods = periods + self.fourier = fourier + self.dropout = nn.Dropout(p=dropout) + if periods: + self.period_emb = PeriodEmbedding(periods) + + if isinstance(hidden_size, (tuple, list)): + if num_layers is not None: + raise ValueError( + "num_layers should be None when hidden_size is specified" + ) + elif isinstance(hidden_size, int): + if not isinstance(num_layers, int): + raise ValueError( + "num_layers should be an int when hidden_size is an int" + ) + hidden_size = [hidden_size] * num_layers + else: + raise ValueError( + f"hidden_size should be list of int or int, but got {type(hidden_size)}" + ) + + # initialize FC layer(s) + cur_size = len(self.input_keys) if input_dim is None else input_dim + if input_dim is None and periods: + # period embeded channel(s) will be doubled automatically + # if input_dim is not specified + cur_size += len(periods) + + if fourier: + self.fourier_emb = FourierEmbedding( + cur_size, fourier["dim"], fourier["scale"] + ) + cur_size = fourier["dim"] + + for i, _size in enumerate(hidden_size): + if weight_norm: + self.linears.append(WeightNormLinear(cur_size, _size)) + elif random_weight: + self.linears.append( + RandomWeightFactorization( + cur_size, + _size, + mean=random_weight["mean"], + std=random_weight["std"], + ) + ) + else: + self.linears.append(nn.Linear(cur_size, _size)) + + # initialize activation function + self.acts.append( + act_mod.get_activation(activation) + if activation != "stan" + else act_mod.get_activation(activation)(_size) + ) + # special initialization for certain activation + # TODO: Adapt code below to a more elegant style + if activation == "siren": + if i == 0: + act_mod.Siren.init_for_first_layer(self.linears[-1]) + else: + act_mod.Siren.init_for_hidden_layer(self.linears[-1]) + + cur_size = _size + + self.linears = nn.LayerList(self.linears) + self.acts = nn.LayerList(self.acts) + if random_weight: + self.last_fc = RandomWeightFactorization( + cur_size, + len(self.output_keys) if output_dim is None else output_dim, + mean=random_weight["mean"], + std=random_weight["std"], + ) + else: + self.last_fc = nn.Linear( + cur_size, + len(self.output_keys) if output_dim is None else output_dim, + ) + + self.skip_connection = skip_connection + + def forward(self, x): + if self._input_transform is not None: + x = self._input_transform(x) + + if self.periods: + x = self.period_emb(x) + + y = self.concat_to_tensor(x, self.input_keys, axis=-1) + + if self.fourier: + y = self.fourier_emb(y) + + for linear, act in zip(self.linears, self.acts): + y = linear(y) + y = act(y) + y = self.dropout(y) # Apply dropout after activation function + y = self.last_fc(y) + y = self.split_to_dict(y, self.output_keys, axis=-1) + + if self._output_transform is not None: + y = self._output_transform(x, y) + return y diff --git a/ppsci/arch/tadf.py b/ppsci/arch/tadf.py new file mode 100644 index 000000000..f1ef01e68 --- /dev/null +++ b/ppsci/arch/tadf.py @@ -0,0 +1,249 @@ +from typing import Dict +from typing import Optional +from typing import Tuple +from typing import Union + +import numpy as np +import paddle +import paddle.nn as nn + +from ppsci.arch import activation as act_mod +from ppsci.arch import base +from ppsci.utils import initializer + + +class WeightNormLinear(nn.Layer): + def __init__(self, in_features: int, out_features: int, bias: bool = True) -> None: + super().__init__() + self.in_features = in_features + self.out_features = out_features + self.weight_v = self.create_parameter((in_features, out_features)) + self.weight_g = self.create_parameter((out_features,)) + if bias: + self.bias = self.create_parameter((out_features,)) + else: + self.bias = None + self._init_weights() + + def _init_weights(self) -> None: + initializer.xavier_uniform_(self.weight_v) + initializer.constant_(self.weight_g, 1.0) + if self.bias is not None: + initializer.constant_(self.bias, 0.0) + + def forward(self, input): + norm = self.weight_v.norm(p=2, axis=0, keepdim=True) + weight = self.weight_g * self.weight_v / norm + return nn.functional.linear(input, weight, self.bias) + + +class RandomWeightFactorization(nn.Layer): + def __init__( + self, + in_features: int, + out_features: int, + bias: bool = True, + mean: float = 0.5, + std: float = 0.1, + ): + super().__init__() + self.in_features = in_features + self.out_features = out_features + self.weight_v = self.create_parameter((in_features, out_features)) + self.weight_g = self.create_parameter((out_features,)) + if bias: + self.bias = self.create_parameter((out_features,)) + else: + self.bias = None + + self._init_weights(mean, std) + + def _init_weights(self, mean, std): + with paddle.no_grad(): + initializer.glorot_normal_(self.weight_v) + + nn.initializer.Normal(mean, std)(self.weight_g) + paddle.assign(paddle.exp(self.weight_g), self.weight_g) + paddle.assign(self.weight_v / self.weight_g, self.weight_v) + if self.bias is not None: + initializer.constant_(self.bias, 0.0) + + self.weight_g.stop_gradient = False + self.weight_v.stop_gradient = False + self.bias.stop_gradient = False + + def forward(self, input): + return nn.functional.linear(input, self.weight_g * self.weight_v, self.bias) + + +class PeriodEmbedding(nn.Layer): + def __init__(self, periods: Dict[str, Tuple[float, bool]]): + super().__init__() + self.freqs_dict = { + k: self.create_parameter( + [], + attr=paddle.ParamAttr(trainable=trainable), + default_initializer=nn.initializer.Constant(2 * np.pi / float(p)), + ) # mu = 2*pi / period for sin/cos function + for k, (p, trainable) in periods.items() + } + self.freqs = nn.ParameterList(list(self.freqs_dict.values())) + + def forward(self, x: Dict[str, paddle.Tensor]): + y = {k: v for k, v in x.items()} # shallow copy to avoid modifying input dict + + for k, w in self.freqs_dict.items(): + y[k] = paddle.concat([paddle.cos(w * x[k]), paddle.sin(w * x[k])], axis=-1) + + return y + + +class FourierEmbedding(nn.Layer): + def __init__(self, in_features, out_features, scale): + super().__init__() + if out_features % 2 != 0: + raise ValueError(f"out_features must be even, but got {out_features}.") + + self.kernel = self.create_parameter( + [in_features, out_features // 2], + default_initializer=nn.initializer.Normal(std=scale), + ) + + def forward(self, x: paddle.Tensor): + y = paddle.concat( + [ + paddle.cos(x @ self.kernel), + paddle.sin(x @ self.kernel), + ], + axis=-1, + ) + return y + + +class TADF(base.Arch): + def __init__( + self, + input_keys: Tuple[str, ...], + output_keys: Tuple[str, ...], + num_layers: int, + hidden_size: Union[int, Tuple[int, ...]], + activation: str = "tanh", + skip_connection: bool = False, + weight_norm: bool = False, + input_dim: Optional[int] = None, + output_dim: Optional[int] = None, + periods: Optional[Dict[int, Tuple[float, bool]]] = None, + fourier: Optional[Dict[str, Union[float, int]]] = None, + random_weight: Optional[Dict[str, float]] = None, + dropout: Optional[float] = 0.5, + ): + super().__init__() + self.input_keys = input_keys + self.output_keys = output_keys + self.linears = [] + self.acts = [] + self.periods = periods + self.fourier = fourier + self.dropout = nn.Dropout(p=dropout) + if periods: + self.period_emb = PeriodEmbedding(periods) + + if isinstance(hidden_size, (tuple, list)): + if num_layers is not None: + raise ValueError( + "num_layers should be None when hidden_size is specified" + ) + elif isinstance(hidden_size, int): + if not isinstance(num_layers, int): + raise ValueError( + "num_layers should be an int when hidden_size is an int" + ) + hidden_size = [hidden_size] * num_layers + else: + raise ValueError( + f"hidden_size should be list of int or int, but got {type(hidden_size)}" + ) + + # initialize FC layer(s) + cur_size = len(self.input_keys) if input_dim is None else input_dim + if input_dim is None and periods: + # period embeded channel(s) will be doubled automatically + # if input_dim is not specified + cur_size += len(periods) + + if fourier: + self.fourier_emb = FourierEmbedding( + cur_size, fourier["dim"], fourier["scale"] + ) + cur_size = fourier["dim"] + + for i, _size in enumerate(hidden_size): + if weight_norm: + self.linears.append(WeightNormLinear(cur_size, _size)) + elif random_weight: + self.linears.append( + RandomWeightFactorization( + cur_size, + _size, + mean=random_weight["mean"], + std=random_weight["std"], + ) + ) + else: + self.linears.append(nn.Linear(cur_size, _size)) + + # initialize activation function + self.acts.append( + act_mod.get_activation(activation) + if activation != "stan" + else act_mod.get_activation(activation)(_size) + ) + # special initialization for certain activation + # TODO: Adapt code below to a more elegant style + if activation == "siren": + if i == 0: + act_mod.Siren.init_for_first_layer(self.linears[-1]) + else: + act_mod.Siren.init_for_hidden_layer(self.linears[-1]) + + cur_size = _size + + self.linears = nn.LayerList(self.linears) + self.acts = nn.LayerList(self.acts) + if random_weight: + self.last_fc = RandomWeightFactorization( + cur_size, + len(self.output_keys) if output_dim is None else output_dim, + mean=random_weight["mean"], + std=random_weight["std"], + ) + else: + self.last_fc = nn.Linear( + cur_size, + len(self.output_keys) if output_dim is None else output_dim, + ) + + self.skip_connection = skip_connection + + def forward(self, x): + if self._input_transform is not None: + x = self._input_transform(x) + + if self.periods: + x = self.period_emb(x) + + y = self.concat_to_tensor(x, self.input_keys, axis=-1) + + if self.fourier: + y = self.fourier_emb(y) + + for linear, act in zip(self.linears, self.acts): + y = linear(y) + y = act(y) + y = self.dropout(y) # Apply dropout after activation function + y = self.last_fc(y) + y = self.split_to_dict(y, self.output_keys, axis=-1) + + if self._output_transform is not None: + y = self._output_transform(x, y) + return y diff --git a/requirements.txt b/requirements.txt index 7efcb16d5..98c918362 100644 --- a/requirements.txt +++ b/requirements.txt @@ -9,6 +9,7 @@ numpy>=1.20.0,<2.0.0 pydantic>=2.5.0 pyevtk pyyaml +rdkit requests scikit-learn<1.5.0 scikit-optimize