diff --git a/apps/meteor/client/components/message/content/attachments/file/GenericFileAttachment.tsx b/apps/meteor/client/components/message/content/attachments/file/GenericFileAttachment.tsx
index 2e0fb7107d983..ee6d7978d3eff 100644
--- a/apps/meteor/client/components/message/content/attachments/file/GenericFileAttachment.tsx
+++ b/apps/meteor/client/components/message/content/attachments/file/GenericFileAttachment.tsx
@@ -15,6 +15,7 @@ import { getFileExtension } from '../../../../../../lib/utils/getFileExtension';
 import { forAttachmentDownload, registerDownloadForUid } from '../../../../../hooks/useDownloadFromServiceWorker';
 import MessageCollapsible from '../../../MessageCollapsible';
 import AttachmentSize from '../structure/AttachmentSize';
+import { useOpenEncryptedPdf } from './hooks/useOpenEncryptedPdf';
 
 const openDocumentViewer = window.RocketChatDesktop?.openDocumentViewer;
 
@@ -31,24 +32,31 @@ const GenericFileAttachment = ({
 	const getURL = useMediaUrl();
 	const uid = useId();
 	const { t } = useTranslation();
+	const openEncryptedPdf = useOpenEncryptedPdf();
 
-	const handleTitleClick = (event: UIEvent): void => {
+	const handleTitleClick = async (event: UIEvent): Promise<void> => {
 		if (!link) {
 			return;
 		}
 
-		if (openDocumentViewer && format === 'PDF') {
+		const isEncrypted = link.includes('/file-decrypt/');
+
+		if (format === 'PDF' && openDocumentViewer) {
 			event.preventDefault();
 
+			if (isEncrypted) {
+				openEncryptedPdf(link, title, size, format, openDocumentViewer);
+				return;
+			}
+
 			const url = new URL(getURL(link), window.location.origin);
 			url.searchParams.set('contentDisposition', 'inline');
 			openDocumentViewer(url.toString(), format, '');
 			return;
 		}
 
-		if (link.includes('/file-decrypt/')) {
+		if (isEncrypted) {
 			event.preventDefault();
-
 			registerDownloadForUid(uid, t, title);
 			forAttachmentDownload(uid, link);
 		}
diff --git a/apps/meteor/client/components/message/content/attachments/file/hooks/useOpenEncryptedPdf.tsx b/apps/meteor/client/components/message/content/attachments/file/hooks/useOpenEncryptedPdf.tsx
new file mode 100644
index 0000000000000..45b5d567fc2c7
--- /dev/null
+++ b/apps/meteor/client/components/message/content/attachments/file/hooks/useOpenEncryptedPdf.tsx
@@ -0,0 +1,76 @@
+import { useMediaUrl } from '@rocket.chat/ui-contexts';
+import { useId, useEffect, useRef } from 'react';
+import { useTranslation } from 'react-i18next';
+
+import { forAttachmentDownload, registerDownloadForUid } from '../../../../../../hooks/useDownloadFromServiceWorker';
+
+export const useOpenEncryptedPdf = () => {
+	const getURL = useMediaUrl();
+	const pdfPreviewSizeLimit = window.RocketChatDesktop?.getE2ePdfPreviewSizeLimit?.() ?? 10;
+	const pdfPreviewSizeLimitInBytes = pdfPreviewSizeLimit * 1024 * 1024;
+	const uid = useId();
+	const { t } = useTranslation();
+
+	const blobUrlRef = useRef<string | undefined>(undefined);
+	const abortControllerRef = useRef<AbortController | null>(null);
+
+	useEffect(() => {
+		return () => {
+			if (abortControllerRef.current) {
+				abortControllerRef.current.abort();
+			}
+			if (blobUrlRef.current) {
+				URL.revokeObjectURL(blobUrlRef.current);
+				blobUrlRef.current = undefined;
+			}
+		};
+	}, []);
+
+	const openEncryptedPdf = async (
+		link: string,
+		title: string | undefined,
+		size: number | undefined,
+		format: string,
+		openDocumentViewer: (url: string, format: string, options: any) => void,
+	) => {
+		if (size && size > pdfPreviewSizeLimitInBytes) {
+			registerDownloadForUid(uid, t, title);
+			forAttachmentDownload(uid, link);
+			return;
+		}
+
+		if (blobUrlRef.current) {
+			URL.revokeObjectURL(blobUrlRef.current);
+			blobUrlRef.current = undefined;
+		}
+
+		if (abortControllerRef.current) {
+			abortControllerRef.current.abort();
+		}
+
+		const abortController = new AbortController();
+		abortControllerRef.current = abortController;
+
+		try {
+			const response = await fetch(getURL(link), {
+				signal: abortController.signal,
+			});
+			if (!response.ok) {
+				throw new Error(`Failed to fetch encrypted PDF: ${response.status}`);
+			}
+			const blob = await response.blob();
+			if (abortController.signal.aborted || abortControllerRef.current !== abortController) {
+				return;
+			}
+			const blobUrl = URL.createObjectURL(blob);
+			blobUrlRef.current = blobUrl;
+			openDocumentViewer(blobUrl, format, title ?? '');
+		} catch (error: any) {
+			if (error.name !== 'AbortError') {
+				console.error('Error opening preview of encrypted PDF', error);
+			}
+		}
+	};
+
+	return openEncryptedPdf;
+};
diff --git a/packages/desktop-api/src/index.ts b/packages/desktop-api/src/index.ts
index 5344ad5d18005..2d7b18c5cabb9 100644
--- a/packages/desktop-api/src/index.ts
+++ b/packages/desktop-api/src/index.ts
@@ -63,5 +63,6 @@ export interface IRocketChatDesktop {
 	setUserToken: (token: string, userId: string) => void;
 	openDocumentViewer: (url: string, format: string, options: any) => void;
 	reloadServer: () => void;
+	getE2ePdfPreviewSizeLimit: () => number;
 	openInBrowser: (url: string) => void;
 }