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[Rohit-Satyam]

When trying to access the scReClassify website, the website is not available.

[Rohit-Satyam]

Hi @taiyunkim

So I am working with a single cell atlas that had issues with cell annotation. I call these "original annotations". I then use 4 bulk RNAseq reference dataset and used consensus of them all to do the annotation and then confirm the the consensus annotation while viewing UMAP and some marker genes. I call these "consensus annotations".

When I run scReClassify using "original annotations" I see a lot of cells to be reclassified (~750 cells reclassified) as opposed to when I run it using "Consensus annotation" (~270 cells reclassified). So does it mean that my consensus annotations are much more robust? Does it happen when scReClassify will stop reclassifying cells as we move closer to the correct cell labels? Does it mean that one should run scReClassify iteratively on the labels provided by scReClassify until it stops correction?