diff --git a/python/scripts/run_emscripten_tests.py b/python/scripts/run_emscripten_tests.py
index 406dfc54e4fc..a4f9ce9d9a28 100644
--- a/python/scripts/run_emscripten_tests.py
+++ b/python/scripts/run_emscripten_tests.py
@@ -116,7 +116,7 @@ def end_headers(self):
 def run_server_thread(dist_dir, q):
     global _SERVER_ADDRESS
     os.chdir(dist_dir)
-    server = http.server.HTTPServer(("", 0), TemplateOverrider)
+    server = http.server.HTTPServer(("127.0.0.1", 0), TemplateOverrider)
     q.put(server.server_address)
     print(f"Starting server for {dist_dir} at: {server.server_address}")
     server.serve_forever()
@@ -280,6 +280,7 @@ def _load_pyarrow_in_runner(driver, wheel_name):
 if "pyarrow" not in sys.modules:
     await micropip.install("hypothesis")
     import pyodide_js as pjs
+    await pjs.loadPackage("tzdata")
     await pjs.loadPackage("numpy")
     await pjs.loadPackage("pandas")
     import pytest
diff --git a/python/setup.py b/python/setup.py
index 4f2bf7585e13..02e7cb4614de 100755
--- a/python/setup.py
+++ b/python/setup.py
@@ -126,6 +126,9 @@ def run(self):
 
     def _update_stubs(self):
         """Copy stubs to build directory, then inject docstrings into the copies."""
+        if is_emscripten:
+            # stubs are not supported in Emscripten build
+            return
         stubs_dir = pjoin(setup_dir, 'pyarrow-stubs')
         if not os.path.exists(stubs_dir):
             return