diff --git a/.github/workflows/ci_examples_python.yml b/.github/workflows/ci_examples_python.yml
new file mode 100644
index 000000000..6eb659ca0
--- /dev/null
+++ b/.github/workflows/ci_examples_python.yml
@@ -0,0 +1,98 @@
+# This workflow performs tests in Python.
+name: Python Examples
+
+on:
+  workflow_call:
+    inputs:
+      dafny:
+        description: "The Dafny version to run"
+        required: true
+        type: string
+      regenerate-code:
+        description: "Regenerate code using smithy-dafny"
+        required: false
+        default: false
+        type: boolean
+      mpl-version:
+        description: "MPL version to use"
+        required: false
+        type: string
+      mpl-head:
+        description: "Running on MPL HEAD"
+        required: false
+        default: false
+        type: boolean
+
+jobs:
+  testPython:
+    strategy:
+      max-parallel: 1
+      matrix:
+        python-version: [3.11, 3.12, 3.13]
+        os: [macos-13]
+    runs-on: ${{ matrix.os }}
+    permissions:
+      id-token: write
+      contents: read
+    steps:
+      - name: Configure AWS Credentials
+        uses: aws-actions/configure-aws-credentials@v4
+        with:
+          aws-region: us-west-2
+          role-to-assume: arn:aws:iam::370957321024:role/GitHub-CI-DDBEC-Dafny-Role-us-west-2
+          role-session-name: DDBEC-Dafny-Python-Tests
+
+      - uses: actions/checkout@v3
+        with:
+          submodules: recursive
+
+      - name: Setup Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v4
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Setup Python ${{ matrix.python-version }} for running tests
+        run: |
+          python -m pip install --upgrade pip
+          pip install --upgrade tox
+          pip install poetry
+
+      - name: Setup Dafny
+        uses: ./submodules/MaterialProviders/.github/actions/setup_dafny/
+        with:
+          dafny-version: ${{ inputs.dafny }}
+
+      - name: Update MPL submodule if using MPL HEAD
+        if: ${{ inputs.mpl-head == true }}
+        working-directory: submodules/MaterialProviders
+        run: |
+          git checkout main
+          git pull
+          git submodule update --init --recursive
+          git rev-parse HEAD
+
+      - name: Install Smithy-Dafny codegen dependencies
+        uses: ./.github/actions/install_smithy_dafny_codegen_dependencies
+
+      - name: Regenerate code using smithy-dafny if necessary
+        if: ${{ inputs.regenerate-code }}
+        uses: ./.github/actions/polymorph_codegen
+        with:
+          dafny: ${{ env.DAFNY_VERSION }}
+          library: DynamoDbEncryption
+          diff-generated-code: false
+          update-and-regenerate-mpl: true
+
+      - name: Build and locally deploy dependencies for examples
+        shell: bash
+        working-directory: ./DynamoDbEncryption
+        run: |
+          make transpile_python
+
+      - name: Test DynamoDbEncryption Examples
+        working-directory: ./Examples/runtimes/python
+        run: |
+          # Run simple examples
+          tox -e dynamodbencryption
+          # Run migration examples
+          # tox -e migration
diff --git a/.github/workflows/ci_static_analysis_python.yml b/.github/workflows/ci_static_analysis_python.yml
new file mode 100644
index 000000000..2559227a6
--- /dev/null
+++ b/.github/workflows/ci_static_analysis_python.yml
@@ -0,0 +1,79 @@
+# This workflow performs static analysis in Python.
+name: Python Static Analysis
+
+on:
+  workflow_call:
+    inputs:
+      regenerate-code:
+        description: "Regenerate code using smithy-dafny"
+        required: false
+        default: false
+        type: boolean
+      mpl-version:
+        description: "MPL version to use"
+        required: false
+        type: string
+      mpl-head:
+        description: "Running on MPL HEAD"
+        required: false
+        default: false
+        type: boolean
+
+jobs:
+  testPython:
+    strategy:
+      matrix:
+        python-version: [3.11]
+        os: [ubuntu-latest]
+    runs-on: ${{ matrix.os }}
+    permissions:
+      id-token: write
+      contents: read
+    steps:
+      - name: Configure AWS Credentials
+        uses: aws-actions/configure-aws-credentials@v4
+        with:
+          aws-region: us-west-2
+          role-to-assume: arn:aws:iam::370957321024:role/GitHub-CI-DDBEC-Dafny-Role-us-west-2
+          role-session-name: DDBEC-Dafny-Python-Tests
+
+      - uses: actions/checkout@v3
+        with:
+          submodules: recursive
+
+      - name: Setup Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v4
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Setup Python ${{ matrix.python-version }} for running tests
+        run: |
+          python -m pip install --upgrade pip
+          pip install --upgrade tox
+          pip install poetry
+
+      - name: Update MPL submodule if using MPL HEAD
+        if: ${{ inputs.mpl-head == true }}
+        working-directory: submodules/MaterialProviders
+        run: |
+          git checkout main
+          git pull
+          git submodule update --init --recursive
+          git rev-parse HEAD
+
+      - name: Install Smithy-Dafny codegen dependencies
+        uses: ./.github/actions/install_smithy_dafny_codegen_dependencies
+
+      - name: Regenerate code using smithy-dafny if necessary
+        if: ${{ inputs.regenerate-code }}
+        uses: ./.github/actions/polymorph_codegen
+        with:
+          dafny: ${{ env.DAFNY_VERSION }}
+          library: DynamoDbEncryption
+          diff-generated-code: false
+          update-and-regenerate-mpl: true
+
+      - name: Run static analysis
+        working-directory: ./DynamoDbEncryption/runtimes/python
+        run: |
+          tox -e lint-check
diff --git a/.github/workflows/ci_test_python.yml b/.github/workflows/ci_test_python.yml
new file mode 100644
index 000000000..51be31292
--- /dev/null
+++ b/.github/workflows/ci_test_python.yml
@@ -0,0 +1,131 @@
+# This workflow runs only Dafny-transpiled Python tests.
+name: test python
+
+on:
+  workflow_call:
+    inputs:
+      dafny:
+        description: "The Dafny version to run"
+        required: true
+        type: string
+      regenerate-code:
+        description: "Regenerate code using smithy-dafny"
+        required: false
+        default: false
+        type: boolean
+      mpl-head:
+        description: "Running on MPL HEAD"
+        required: false
+        default: false
+        type: boolean
+
+jobs:
+  testPython:
+    strategy:
+      fail-fast: false
+      matrix:
+        library: [DynamoDbEncryption]
+        python-version: ["3.11", "3.12", "3.13"]
+        os: [
+            macos-13,
+            ubuntu-22.04,
+            # Dafny-transpiled Python tests use a PYTHONPATH hack that doesn't work on Windows.
+            # Windows is tested with non-Dafny-transpiled Python tests.
+            # windows-latest
+          ]
+    runs-on: ${{ matrix.os }}
+    permissions:
+      id-token: write
+      contents: read
+    steps:
+      - name: Support longpaths on Git checkout
+        run: |
+          git config --global core.longpaths true
+      - uses: actions/checkout@v3
+        with:
+          submodules: recursive
+
+      - name: Setup Python
+        uses: actions/setup-python@v4
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Setup Python ${{ matrix.python-version }} for running tests
+        run: |
+          python -m pip install --upgrade pip
+          pip install --upgrade tox
+          pip install poetry
+
+      - name: Setup Dafny
+        uses: ./submodules/MaterialProviders/.github/actions/setup_dafny/
+        with:
+          dafny-version: ${{ inputs.dafny }}
+
+      - name: Update MPL submodule if using MPL HEAD
+        if: ${{ inputs.mpl-head == true }}
+        working-directory: submodules/MaterialProviders
+        run: |
+          git checkout main
+          git pull
+          git submodule update --init --recursive
+          git rev-parse HEAD
+
+      - name: Install Smithy-Dafny codegen dependencies
+        uses: ./.github/actions/install_smithy_dafny_codegen_dependencies
+
+      - name: Regenerate code using smithy-dafny if necessary
+        if: ${{ inputs.regenerate-code }}
+        uses: ./.github/actions/polymorph_codegen
+        with:
+          dafny: ${{ env.DAFNY_VERSION }}
+          library: ${{ matrix.library }}
+          diff-generated-code: false
+          update-and-regenerate-mpl: true
+
+      - name: Download Dependencies
+        working-directory: ./${{ matrix.library }}
+        run: make setup_python
+
+      - name: Configure AWS Credentials
+        uses: aws-actions/configure-aws-credentials@v4
+        with:
+          aws-region: us-west-2
+          role-to-assume: arn:aws:iam::370957321024:role/GitHub-CI-DDBEC-Dafny-Role-us-west-2
+          role-session-name: DDBEC-Dafny-Net-Tests
+
+      - name: Compile ${{ matrix.library }} implementation
+        shell: bash
+        working-directory: ./${{ matrix.library }}
+        run: |
+          # This works because `node` is installed by default on GHA runners
+          CORES=$(node -e 'console.log(os.cpus().length)')
+          make transpile_python CORES=$CORES
+
+      - name: Test ${{ matrix.library }} Dafny-transpiled Python tests
+        # Dafny-transpiled Python tests use a PYTHONPATH hack that doesn't work on Windows.
+        # Windows is tested with non-Dafny-transpiled Python tests.
+        if: ${{ matrix.os != 'windows-latest' }}
+        working-directory: ./${{ matrix.library }}/runtimes/python
+        shell: bash
+        run: |
+          tox -e dafnytests
+
+      - name: Test ${{ matrix.library }} Python unit tests
+        working-directory: ./${{ matrix.library }}/runtimes/python
+        shell: bash
+        run: |
+          tox -e unit
+
+      - name: Test ${{ matrix.library }} Python integration tests
+        working-directory: ./${{ matrix.library }}/runtimes/python
+        shell: bash
+        run: |
+          tox -e integ
+
+      - name: Test ${{ matrix.library }} Python coverage
+        working-directory: ./${{ matrix.library }}/runtimes/python
+        shell: bash
+        run: |
+          tox -e encrypted-interface-coverage
+          tox -e client-to-resource-conversions-coverage
+          tox -e resource-to-client-conversions-coverage
diff --git a/.github/workflows/ci_test_vector_python.yml b/.github/workflows/ci_test_vector_python.yml
new file mode 100644
index 000000000..f525fdaec
--- /dev/null
+++ b/.github/workflows/ci_test_vector_python.yml
@@ -0,0 +1,111 @@
+# This workflow performs test vectors in Python.
+name: Library Python Test Vectors
+
+on:
+  workflow_call:
+    inputs:
+      dafny:
+        description: "The Dafny version to run"
+        required: true
+        type: string
+      regenerate-code:
+        description: "Regenerate code using smithy-dafny"
+        required: false
+        default: false
+        type: boolean
+      mpl-version:
+        description: "MPL version to use"
+        required: false
+        type: string
+      mpl-head:
+        description: "Running on MPL HEAD"
+        required: false
+        default: false
+        type: boolean
+
+jobs:
+  testPython:
+    strategy:
+      fail-fast: false
+      matrix:
+        library: [TestVectors]
+        python-version: [3.11, 3.12, 3.13]
+        # Only ubuntu for now;
+        # As of 4.10.1, Dafny's Python JSON processing is still very slow (1 hour to run test vectors on ubuntu)
+        # and Github's macOS runners are also very slow (~2x slower than ubuntu).
+        # If Dafny's JSON processing speed is improved, we can add macOS back.
+        os: [ubuntu-22.04]
+        interface: [client, resource, table]
+    runs-on: ${{ matrix.os }}
+    permissions:
+      id-token: write
+      contents: read
+    steps:
+      - name: Setup DynamoDB Local
+        uses: rrainn/dynamodb-action@v4.0.0
+        with:
+          port: 8000
+          cors: "*"
+
+      - name: Configure AWS Credentials
+        uses: aws-actions/configure-aws-credentials@v4
+        with:
+          aws-region: us-west-2
+          role-to-assume: arn:aws:iam::370957321024:role/GitHub-CI-DDBEC-Dafny-Role-us-west-2
+          role-session-name: DDBEC-Dafny-Python-Tests
+          role-duration-seconds: 7200
+
+      - uses: actions/checkout@v3
+        with:
+          submodules: recursive
+
+      - name: Setup Dafny
+        uses: ./submodules/MaterialProviders/.github/actions/setup_dafny/
+        with:
+          dafny-version: ${{ inputs.dafny }}
+
+      - name: Update MPL submodule if using MPL HEAD
+        if: ${{ inputs.mpl-head == true }}
+        working-directory: submodules/MaterialProviders
+        run: |
+          git checkout main
+          git pull
+          git submodule update --init --recursive
+          git rev-parse HEAD
+
+      - name: Install Smithy-Dafny codegen dependencies
+        uses: ./.github/actions/install_smithy_dafny_codegen_dependencies
+
+      - name: Regenerate code using smithy-dafny if necessary
+        if: ${{ inputs.regenerate-code }}
+        uses: ./.github/actions/polymorph_codegen
+        with:
+          dafny: ${{ env.DAFNY_VERSION }}
+          library: ${{ matrix.library }}
+          diff-generated-code: false
+          update-and-regenerate-mpl: true
+
+      - name: Setup Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v4
+        with:
+          python-version: ${{ matrix.python-version }}
+
+      - name: Setup Python ${{ matrix.python-version }} for running tests
+        run: |
+          python -m pip install --upgrade pip
+          pip install --upgrade tox
+          pip install poetry
+
+      - name: Build Python TestVectors implementation
+        shell: bash
+        working-directory: ${{matrix.library}}
+        run: |
+          # This works because `node` is installed by default on GHA runners
+          CORES=$(node -e 'console.log(os.cpus().length)')
+          make transpile_python CORES=$CORES
+
+      - name: Test Python TestVectors with ${{matrix.interface}} interface
+        working-directory: ${{matrix.library}}
+        run: |
+          cp runtimes/java/*.json runtimes/python
+          make test_python_${{matrix.interface}}_interface
diff --git a/.github/workflows/daily_ci.yml b/.github/workflows/daily_ci.yml
index ed5cf7e78..a00038ac5 100644
--- a/.github/workflows/daily_ci.yml
+++ b/.github/workflows/daily_ci.yml
@@ -61,6 +61,26 @@ jobs:
     uses: ./.github/workflows/library_rust_tests.yml
     with:
       dafny: ${{needs.getVersion.outputs.version}}
+  daily-ci-python:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  daily-ci-python-examples:
+    needs: getVersion
+    uses: ./.github/workflows/ci_examples_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  daily-ci-python-test-vectors:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_vector_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  daily-ci-python-static-analysis:
+    needs: getVersion
+    uses: ./.github/workflows/ci_static_analysis_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
   daily-ci-net-test-vectors:
     needs: getVersion
     uses: ./.github/workflows/ci_test_vector_net.yml
diff --git a/.github/workflows/manual.yml b/.github/workflows/manual.yml
index 8679b4f30..ca703d850 100644
--- a/.github/workflows/manual.yml
+++ b/.github/workflows/manual.yml
@@ -57,6 +57,26 @@ jobs:
     with:
       dafny: ${{ inputs.dafny }}
       regenerate-code: ${{ inputs.regenerate-code }}
+  manual-ci-python:
+    uses: ./.github/workflows/ci_test_python.yml
+    with:
+      dafny: ${{ inputs.dafny }}
+      regenerate-code: ${{ inputs.regenerate-code }}
+  manual-ci-python-examples:
+    uses: ./.github/workflows/ci_examples_python.yml
+    with:
+      dafny: ${{ inputs.dafny }}
+      regenerate-code: ${{ inputs.regenerate-code }}
+  manual-ci-python-test-vectors:
+    uses: ./.github/workflows/ci_test_vector_python.yml
+    with:
+      dafny: ${{ inputs.dafny }}
+      regenerate-code: ${{ inputs.regenerate-code }}
+  manual-ci-python-static-analysis:
+    uses: ./.github/workflows/ci_static_analysis_python.yml
+    with:
+      dafny: ${{ inputs.dafny }}
+      regenerate-code: ${{ inputs.regenerate-code }}
   manual-ci-net-test-vectors:
     uses: ./.github/workflows/ci_test_vector_net.yml
     with:
diff --git a/.github/workflows/mpl-head.yml b/.github/workflows/mpl-head.yml
index 6e2e06234..fffa31e0d 100644
--- a/.github/workflows/mpl-head.yml
+++ b/.github/workflows/mpl-head.yml
@@ -73,6 +73,18 @@ jobs:
     with:
       dafny: ${{needs.getVersion.outputs.version}}
       mpl-head: true
+  mpl-head-ci-python:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+      mpl-head: true
+  mpl-head-ci-python-examples:
+    needs: getVersion
+    uses: ./.github/workflows/ci_examples_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+      mpl-head: true
   mpl-head-ci-net-test-vectors:
     needs: getVersion
     uses: ./.github/workflows/ci_test_vector_net.yml
diff --git a/.github/workflows/nightly.yml b/.github/workflows/nightly.yml
index eb4bc6e20..ba72181f4 100644
--- a/.github/workflows/nightly.yml
+++ b/.github/workflows/nightly.yml
@@ -58,6 +58,18 @@ jobs:
     with:
       dafny: "nightly-latest"
       regenerate-code: true
+  dafny-nightly-python:
+    if: github.event_name != 'schedule' || github.repository_owner == 'aws'
+    uses: ./.github/workflows/ci_test_python.yml
+    with:
+      dafny: "nightly-latest"
+      regenerate-code: true
+  dafny-nightly-python-test-vectors:
+    if: github.event_name != 'schedule' || github.repository_owner == 'aws'
+    uses: ./.github/workflows/ci_test_vector_python.yml
+    with:
+      dafny: "nightly-latest"
+      regenerate-code: true
   dafny-nightly-test-vectors-net:
     if: github.event_name != 'schedule' || github.repository_owner == 'aws'
     uses: ./.github/workflows/ci_test_vector_net.yml
diff --git a/.github/workflows/pull.yml b/.github/workflows/pull.yml
index 3f237ee0d..e9e237653 100644
--- a/.github/workflows/pull.yml
+++ b/.github/workflows/pull.yml
@@ -54,6 +54,24 @@ jobs:
     uses: ./.github/workflows/library_rust_tests.yml
     with:
       dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python-testvectors:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_vector_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python-examples:
+    needs: getVersion
+    uses: ./.github/workflows/ci_examples_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python-static-analysis:
+    needs: getVersion
+    uses: ./.github/workflows/ci_static_analysis_python.yml
   pr-ci-net-test-vectors:
     needs: getVersion
     uses: ./.github/workflows/ci_test_vector_net.yml
@@ -80,6 +98,10 @@ jobs:
       - pr-ci-rust
       - pr-ci-net-test-vectors
       - pr-ci-net-examples
+      - pr-ci-python
+      - pr-ci-python-testvectors
+      - pr-ci-python-examples
+      - pr-ci-python-static-analysis
     runs-on: ubuntu-22.04
     steps:
       - name: Verify all required jobs passed
diff --git a/.github/workflows/push.yml b/.github/workflows/push.yml
index 9e49cf133..b3f66e2d2 100644
--- a/.github/workflows/push.yml
+++ b/.github/workflows/push.yml
@@ -56,6 +56,24 @@ jobs:
     uses: ./.github/workflows/library_rust_tests.yml
     with:
       dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python-examples:
+    needs: getVersion
+    uses: ./.github/workflows/ci_examples_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
+  pr-ci-python-static-analysis:
+    needs: getVersion
+    uses: ./.github/workflows/ci_static_analysis_python.yml
+  pr-ci-python-test-vectors:
+    needs: getVersion
+    uses: ./.github/workflows/ci_test_vector_python.yml
+    with:
+      dafny: ${{needs.getVersion.outputs.version}}
   pr-ci-net-test-vectors:
     needs: getVersion
     uses: ./.github/workflows/ci_test_vector_net.yml
diff --git a/DynamoDbEncryption/runtimes/python/tox.ini b/DynamoDbEncryption/runtimes/python/tox.ini
new file mode 100644
index 000000000..a4edd1639
--- /dev/null
+++ b/DynamoDbEncryption/runtimes/python/tox.ini
@@ -0,0 +1,108 @@
+[tox]
+isolated_build = True
+envlist =
+  py{311,312,313}-{dafnytests,unit,integ},
+  encrypted-interface-coverage,
+  client-to-resource-conversions-coverage,
+  resource-to-client-conversions-coverage,
+  docs,
+  isort-check,
+  black-check
+
+[testenv:base-command]
+commands = poetry run pytest -s -v -l {posargs}
+
+[testenv]
+skip_install = true
+allowlist_externals = poetry,ruff,black
+passenv = AWS_*
+commands_pre =
+    poetry lock
+    poetry install --with test
+commands =
+    dafnytests: {[testenv:base-command]commands} test/internaldafny/
+    unit: {[testenv:base-command]commands} test/unit/
+    integ: {[testenv:base-command]commands} test/integ/
+
+[testenv:encrypted-interface-coverage]
+description = Run integ + unit tests for encrypted interfaces with coverage
+commands =
+    python -m pytest -s -vv \
+        test/integ/encrypted \
+        test/unit/encrypted \
+        --cov aws_dbesdk_dynamodb.encrypted \
+        --cov-report=term-missing \
+        --cov-fail-under=100
+
+[testenv:client-to-resource-conversions-coverage]
+description = Run boto3 conversion tests with coverage
+commands =
+    python -m pytest -s -vv \
+        test/unit/internal/test_client_to_resource.py \
+        --cov aws_dbesdk_dynamodb.internal.client_to_resource \
+        --cov-report=term-missing \
+        --cov-fail-under=100
+
+[testenv:resource-to-client-conversions-coverage]
+description = Run boto3 conversion tests with coverage
+commands =
+    python -m pytest -s -vv \
+        test/unit/internal/test_resource_to_client.py \
+        --cov aws_dbesdk_dynamodb.internal.resource_to_client \
+        --cov-report=term-missing \
+        --cov-fail-under=100
+
+# Linters
+[testenv:ruff]
+commands_pre =
+    poetry install --with linting
+deps =
+    ruff
+commands =
+    ruff check \
+        src/aws_dbesdk_dynamodb/ \
+        ../../../Examples/runtimes/python/DynamoDBEncryption/ \
+        test/ \
+        {posargs}
+
+[testenv:blacken]
+commands_pre =
+    poetry install --with linting
+deps =
+    black
+basepython = python3
+commands =
+    black --line-length 120 \
+        src/aws_dbesdk_dynamodb/ \
+        ../../../Examples/runtimes/python/DynamoDBEncryption/ \
+        test/ \
+        {posargs}
+
+[testenv:black-check]
+commands_pre =
+    {[testenv:blacken]commands_pre}
+basepython = python3
+deps =
+    {[testenv:blacken]deps}
+commands =
+    {[testenv:blacken]commands} --diff --check
+
+[testenv:lint]
+commands_pre =
+    poetry install --with linting
+deps =
+    black
+basepython = python3
+commands =
+    {[testenv:blacken]commands}
+    {[testenv:ruff]commands} --fix
+
+[testenv:lint-check]
+commands_pre =
+    poetry install --with linting
+deps =
+    black
+basepython = python3
+commands =
+    {[testenv:black-check]commands}
+    {[testenv:ruff]commands}
diff --git a/Examples/runtimes/python/tox.ini b/Examples/runtimes/python/tox.ini
new file mode 100644
index 000000000..b3edda147
--- /dev/null
+++ b/Examples/runtimes/python/tox.ini
@@ -0,0 +1,18 @@
+[tox]
+isolated_build = True
+envlist =
+  py{311,312,313}-{dynamodbencryption,migration}
+
+[testenv:base-command]
+commands = poetry run pytest -s -v -l {posargs}
+
+[testenv]
+skip_install = true
+allowlist_externals = poetry
+passenv = AWS_*
+commands_pre =
+    poetry lock
+    poetry install --with test --no-root
+commands =
+    dynamodbencryption: {[testenv:base-command]commands} DynamoDBEncryption/test/
+    migration: {[testenv:base-command]commands} Migration/PlaintextToAWSDBE/test/
\ No newline at end of file
diff --git a/TestVectors/runtimes/python/tox.ini b/TestVectors/runtimes/python/tox.ini
new file mode 100644
index 000000000..4f64adc59
--- /dev/null
+++ b/TestVectors/runtimes/python/tox.ini
@@ -0,0 +1,26 @@
+[tox]
+isolated_build = True
+envlist =
+  py{311,312,313}
+
+[testenv]
+skip_install = true
+allowlist_externals = poetry
+passenv = AWS_*
+commands_pre =
+    poetry lock
+    poetry install
+commands =
+    poetry run pytest test/ -s -v
+
+[testenv:client]
+commands =
+    poetry run pytest test/client -s -v
+
+[testenv:resource]
+commands =
+    poetry run pytest test/resource -s -v
+
+[testenv:table]
+commands =
+    poetry run pytest test/table -s -v