question

[haeseo00]

Hello @dami82,

I am using this package for the first time to analyze mutation signatures, and I would like to express my gratitude as I find it extremely useful.

I have two questions:

1. How can I generate the figure I attached?
   

2. I used the code below.

I created a plot for 30 COSMIC mutation signatures using the code below and identified the six most frequently occurring mutation signatures across all samples.

Now, I would like to generate a plot only for these six mutation signatures.
How can I do this?

...

# 6. Estimate Exposures to known Mutational Signatures

cosmix <- getCosmicSignatures(forceUseMirror = FALSE, asMutSign = TRUE)

A_matrix <- dcast(merge_vcf, mutType ~ SAMPLEID, fun.aggregate = length, value.var = "SAMPLEID")
View(A_matrix)
A_matrix <- as.data.frame(A_matrix)
rownames(A_matrix) <- A_matrix$mutType
A_matrix$mutType <- NULL
xx <- as.mutation.counts(A_matrix)
xx

blca.expo1 <- resolveMutSignatures(mutCountData = xx, 
                                   signFreqData = cosmix)

blca.exp.1x <- blca.expo1$Results$count.result

msigPlot(blca.exp.1x, main = "COSMIC")

Thank you in advance for your help.