diff --git a/src/tests/issues.targets b/src/tests/issues.targets
index 3e5e3c5b88d8d7..d4daa281d92281 100644
--- a/src/tests/issues.targets
+++ b/src/tests/issues.targets
@@ -426,6 +426,94 @@
         </ExcludeList>
     </ItemGroup>
 
+    <!-- On RV64 vararg is not supported yet -->
+    <ItemGroup Condition="'$(XunitTestBinBase)' != '' and '$(TargetsWindows)' != 'true' and '$(RuntimeFlavor)' == 'coreclr' and '$(TargetArchitecture)' == 'riscv64'">
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i00/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i01/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i02/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i03/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i10/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i11/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i12/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i13/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i30/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i31/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i32/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i33/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i50/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i51/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i52/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i53/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i60/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i61/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i62/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i63/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i70/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i71/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i72/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i73/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i80/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i81/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i82/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/jit64/mcc/interop/mcc_i83/*">
+            <Issue>needs vararg support</Issue>
+        </ExcludeList>
+    </ItemGroup>
+
     <!-- Tests that need to be triaged for vararg usage as that is not supported -->
     <!-- Note these will only be excluded for unix platforms on CoreCLR only -->
     <ItemGroup Condition="'$(XunitTestBinBase)' != '' and '$(TargetsWindows)' != 'true' and '$(RuntimeFlavor)' == 'coreclr'">