diff --git a/archive/opentelemetry-browser-extension-autoinjection/package.json b/archive/opentelemetry-browser-extension-autoinjection/package.json
index 1efd629ff2..fc48117223 100644
--- a/archive/opentelemetry-browser-extension-autoinjection/package.json
+++ b/archive/opentelemetry-browser-extension-autoinjection/package.json
@@ -46,7 +46,7 @@
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     "html-webpack-plugin": "5.3.2",
     "jimp": "0.16.1",
-    "jsdom": "15.2.1",
+    "jsdom": "24.1.1",
     "mocha": "7.2.0",
     "null-loader": "4.0.1",
     "nyc": "15.1.0",
@@ -78,7 +78,7 @@
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     "@opentelemetry/semantic-conventions": "^1.0.0",
     "change-case": "4.1.2",
-    "json5": "2.2.0",
+    "json5": "2.2.2",
     "react": "17.0.2",
     "react-dom": "17.0.2"
   },
diff --git a/examples/connect/package.json b/examples/connect/package.json
index 4acf0fcf9a..300fb24cdd 100644
--- a/examples/connect/package.json
+++ b/examples/connect/package.json
@@ -47,7 +47,7 @@
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     "@opentelemetry/semantic-conventions": "^1.23.0",
     "@opentelemetry/sdk-trace-base": "^0.25.0",
-    "axios": "^0.21.1",
+    "axios": "^1.7.3",
     "cross-env": "^7.0.3",
     "connect": "^3.7.0"
   },
diff --git a/examples/fastify/package-lock.json b/examples/fastify/package-lock.json
index 3eb68c413c..22c92cbf6b 100644
--- a/examples/fastify/package-lock.json
+++ b/examples/fastify/package-lock.json
@@ -21,7 +21,7 @@
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         "@opentelemetry/sdk-trace-node": "~1.19.0",
         "@opentelemetry/semantic-conventions": "~1.19.0",
-        "axios": "^1.6.4",
+        "axios": "^1.7.3",
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         "fastify-cors": "^6.1.0",
@@ -75,25 +75,25 @@
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+      "version": "1.11.1",
+      "resolved": "https://registry.npmjs.org/@grpc/grpc-js/-/grpc-js-1.11.1.tgz",
+      "integrity": "sha512-gyt/WayZrVPH2w/UTLansS7F9Nwld472JxxaETamrM8HNlsa+jSLNyKAZmhxI2Me4c3mQHFiS1wWHDY1g1Kthw==",
       "dependencies": {
-        "@grpc/proto-loader": "^0.7.8",
-        "@types/node": ">=12.12.47"
+        "@grpc/proto-loader": "^0.7.13",
+        "@js-sdsl/ordered-map": "^4.4.2"
       },
       "engines": {
-        "node": "^8.13.0 || >=10.10.0"
+        "node": ">=12.10.0"
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     "node_modules/@grpc/proto-loader": {
-      "version": "0.7.10",
-      "resolved": "https://registry.npmjs.org/@grpc/proto-loader/-/proto-loader-0.7.10.tgz",
-      "integrity": "sha512-CAqDfoaQ8ykFd9zqBDn4k6iWT9loLAlc2ETmDFS9JCD70gDcnA4L3AFEo2iV7KyAtAAHFW9ftq1Fz+Vsgq80RQ==",
+      "version": "0.7.13",
+      "resolved": "https://registry.npmjs.org/@grpc/proto-loader/-/proto-loader-0.7.13.tgz",
+      "integrity": "sha512-AiXO/bfe9bmxBjxxtYxFAXGZvMaN5s8kO+jBHAJCON8rJoB5YS/D6X7ZNc6XQkuHNmyl4CYaMI1fJ/Gn27RGGw==",
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         "long": "^5.0.0",
-        "protobufjs": "^7.2.4",
+        "protobufjs": "^7.2.5",
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@@ -103,10 +103,14 @@
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-      "resolved": "https://registry.npmjs.org/long/-/long-5.2.3.tgz",
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+    "node_modules/@js-sdsl/ordered-map": {
+      "version": "4.4.2",
+      "resolved": "https://registry.npmjs.org/@js-sdsl/ordered-map/-/ordered-map-4.4.2.tgz",
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+      "funding": {
+        "type": "opencollective",
+        "url": "https://opencollective.com/js-sdsl"
+      }
     },
     "node_modules/@opentelemetry/api": {
       "version": "1.7.0",
@@ -725,11 +729,11 @@
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+      "version": "1.7.3",
+      "resolved": "https://registry.npmjs.org/axios/-/axios-1.7.3.tgz",
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+        "follow-redirects": "^1.15.6",
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@@ -1040,9 +1044,9 @@
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+      "version": "3.1.2",
+      "resolved": "https://registry.npmjs.org/escalade/-/escalade-3.1.2.tgz",
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@@ -1560,6 +1564,11 @@
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+    "node_modules/long": {
+      "version": "5.2.3",
+      "resolved": "https://registry.npmjs.org/long/-/long-5.2.3.tgz",
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+    },
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@@ -1786,11 +1795,6 @@
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@@ -2391,32 +2395,30 @@
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+      "version": "1.11.1",
+      "resolved": "https://registry.npmjs.org/@grpc/grpc-js/-/grpc-js-1.11.1.tgz",
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       "requires": {
-        "@grpc/proto-loader": "^0.7.8",
-        "@types/node": ">=12.12.47"
+        "@grpc/proto-loader": "^0.7.13",
+        "@js-sdsl/ordered-map": "^4.4.2"
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-      "version": "0.7.10",
-      "resolved": "https://registry.npmjs.org/@grpc/proto-loader/-/proto-loader-0.7.10.tgz",
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+      "version": "0.7.13",
+      "resolved": "https://registry.npmjs.org/@grpc/proto-loader/-/proto-loader-0.7.13.tgz",
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       "requires": {
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         "long": "^5.0.0",
-        "protobufjs": "^7.2.4",
+        "protobufjs": "^7.2.5",
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-          "resolved": "https://registry.npmjs.org/long/-/long-5.2.3.tgz",
-          "integrity": "sha512-lcHwpNoggQTObv5apGNCTdJrO69eHOZMi4BNC+rTLER8iHAqGrUVeLh/irVIM7zTw2bOXA8T6uNPeujwOLg/2Q=="
-        }
       }
     },
+    "@js-sdsl/ordered-map": {
+      "version": "4.4.2",
+      "resolved": "https://registry.npmjs.org/@js-sdsl/ordered-map/-/ordered-map-4.4.2.tgz",
+      "integrity": "sha512-iUKgm52T8HOE/makSxjqoWhe95ZJA1/G1sYsGev2JDKUSS14KAgg1LHb+Ba+IPow0xflbnSkOsZcO08C7w1gYw=="
+    },
     "@opentelemetry/api": {
       "version": "1.7.0",
       "resolved": "https://registry.npmjs.org/@opentelemetry/api/-/api-1.7.0.tgz",
@@ -2849,11 +2851,11 @@
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-      "resolved": "https://registry.npmjs.org/axios/-/axios-1.6.4.tgz",
-      "integrity": "sha512-heJnIs6N4aa1eSthhN9M5ioILu8Wi8vmQW9iHQ9NUvfkJb0lEEDUiIdQNAuBtfUt3FxReaKdpQA5DbmMOqzF/A==",
+      "version": "1.7.3",
+      "resolved": "https://registry.npmjs.org/axios/-/axios-1.7.3.tgz",
+      "integrity": "sha512-Ar7ND9pU99eJ9GpoGQKhKf58GpUOgnzuaB7ueNQ5BMi0p+LZ5oaEnfF999fAArcTIBwXTCHAmGcHOZJaWPq9Nw==",
       "requires": {
-        "follow-redirects": "^1.15.4",
+        "follow-redirects": "^1.15.6",
         "form-data": "^4.0.0",
         "proxy-from-env": "^1.1.0"
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@@ -3062,9 +3064,9 @@
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     "escalade": {
-      "version": "3.1.1",
-      "resolved": "https://registry.npmjs.org/escalade/-/escalade-3.1.1.tgz",
-      "integrity": "sha512-k0er2gUkLf8O0zKJiAhmkTnJlTvINGv7ygDNPbeIsX/TJjGJZHuh9B2UxbsaEkmlEo9MfhrSzmhIlhRlI2GXnw=="
+      "version": "3.1.2",
+      "resolved": "https://registry.npmjs.org/escalade/-/escalade-3.1.2.tgz",
+      "integrity": "sha512-ErCHMCae19vR8vQGe50xIsVomy19rg6gFu3+r3jkEO46suLMWBksvVyoGgQV+jOfl84ZSOSlmv6Gxa89PmTGmA=="
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@@ -3476,6 +3478,11 @@
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+    "long": {
+      "version": "5.2.3",
+      "resolved": "https://registry.npmjs.org/long/-/long-5.2.3.tgz",
+      "integrity": "sha512-lcHwpNoggQTObv5apGNCTdJrO69eHOZMi4BNC+rTLER8iHAqGrUVeLh/irVIM7zTw2bOXA8T6uNPeujwOLg/2Q=="
+    },
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       "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-6.0.0.tgz",
@@ -3657,13 +3664,6 @@
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diff --git a/examples/fastify/package.json b/examples/fastify/package.json
index f30eef6fa5..e4ce429812 100644
--- a/examples/fastify/package.json
+++ b/examples/fastify/package.json
@@ -48,7 +48,7 @@
     "@opentelemetry/semantic-conventions": "~1.19.0",
     "@opentelemetry/sdk-trace-base": "~1.19.0",
     "cross-env": "^7.0.3",
-    "axios": "^1.6.4",
+    "axios": "^1.7.3",
     "fastify": "^4.25.2",
     "fastify-cors": "^6.1.0",
     "@fastify/express": "^2.3.0",
diff --git a/examples/hapi/package.json b/examples/hapi/package.json
index a16e921b63..4f646e44d7 100644
--- a/examples/hapi/package.json
+++ b/examples/hapi/package.json
@@ -40,7 +40,7 @@
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     "@opentelemetry/sdk-trace-node": "^0.25.0",
     "@opentelemetry/sdk-trace-base": "^0.25.0",
-    "axios": "^0.21.1"
+    "axios": "^1.7.3"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js-contrib#readme",
   "devDependencies": {
diff --git a/examples/meta-node/package.json b/examples/meta-node/package.json
index da4e6a6494..d91a029573 100644
--- a/examples/meta-node/package.json
+++ b/examples/meta-node/package.json
@@ -41,7 +41,7 @@
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     "@opentelemetry/sdk-trace-node": "^0.25.0",
     "@opentelemetry/sdk-trace-base": "^0.25.0",
-    "axios": "^0.21.1",
+    "axios": "^1.7.3",
     "express": "^4.17.1"
   }
 }
diff --git a/package-lock.json b/package-lock.json
index b5a4633aa3..60b87faf61 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -4542,12 +4542,12 @@
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+      "version": "2.12.0",
+      "resolved": "https://registry.npmjs.org/@azure/msal-node/-/msal-node-2.12.0.tgz",
+      "integrity": "sha512-jmk5Im5KujRA2AcyCb0awA3buV8niSrwXZs+NBJWIvxOz76RvNlusGIqi43A0h45BPUy93Qb+CPdpJn82NFTIg==",
       "dev": true,
       "dependencies": {
-        "@azure/msal-common": "14.9.0",
+        "@azure/msal-common": "14.14.0",
         "jsonwebtoken": "^9.0.0",
         "uuid": "^8.3.0"
       },
@@ -4555,6 +4555,15 @@
         "node": ">=16"
       }
     },
+    "node_modules/@azure/msal-node/node_modules/@azure/msal-common": {
+      "version": "14.14.0",
+      "resolved": "https://registry.npmjs.org/@azure/msal-common/-/msal-common-14.14.0.tgz",
+      "integrity": "sha512-OxcOk9H1/1fktHh6//VCORgSNJc2dCQObTm6JNmL824Z6iZSO6eFo/Bttxe0hETn9B+cr7gDouTQtsRq3YPuSQ==",
+      "dev": true,
+      "engines": {
+        "node": ">=0.8.0"
+      }
+    },
     "node_modules/@babel/code-frame": {
       "version": "7.24.7",
       "resolved": "https://registry.npmjs.org/@babel/code-frame/-/code-frame-7.24.7.tgz",
@@ -7155,25 +7164,25 @@
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+      "version": "1.11.1",
+      "resolved": "https://registry.npmjs.org/@grpc/grpc-js/-/grpc-js-1.11.1.tgz",
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-        "@grpc/proto-loader": "^0.7.8",
-        "@types/node": ">=12.12.47"
+        "@grpc/proto-loader": "^0.7.13",
+        "@js-sdsl/ordered-map": "^4.4.2"
       },
       "engines": {
-        "node": "^8.13.0 || >=10.10.0"
+        "node": ">=12.10.0"
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     "node_modules/@grpc/proto-loader": {
-      "version": "0.7.10",
-      "resolved": "https://registry.npmjs.org/@grpc/proto-loader/-/proto-loader-0.7.10.tgz",
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+      "version": "0.7.13",
+      "resolved": "https://registry.npmjs.org/@grpc/proto-loader/-/proto-loader-0.7.13.tgz",
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-        "protobufjs": "^7.2.4",
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@@ -8261,6 +8270,15 @@
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       "dev": true
     },
+    "node_modules/@js-sdsl/ordered-map": {
+      "version": "4.4.2",
+      "resolved": "https://registry.npmjs.org/@js-sdsl/ordered-map/-/ordered-map-4.4.2.tgz",
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+      "funding": {
+        "type": "opencollective",
+        "url": "https://opencollective.com/js-sdsl"
+      }
+    },
     "node_modules/@jsdevtools/coverage-istanbul-loader": {
       "version": "3.0.5",
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@@ -14894,12 +14912,12 @@
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@@ -63843,9 +63837,9 @@
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@@ -66166,56 +66160,39 @@
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-      "resolved": "https://registry.npmjs.org/knex/-/knex-0.95.9.tgz",
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+      "resolved": "https://registry.npmjs.org/knex/-/knex-2.4.0.tgz",
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-        "commander": "^7.1.0",
-        "debug": "4.3.2",
+        "colorette": "2.0.19",
+        "commander": "^9.1.0",
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-        "getopts": "2.2.5",
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         "lodash": "^4.17.21",
         "pg-connection-string": "2.5.0",
-        "rechoir": "0.7.0",
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+          "resolved": "https://registry.npmjs.org/colorette/-/colorette-2.0.19.tgz",
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-          "resolved": "https://registry.npmjs.org/commander/-/commander-7.2.0.tgz",
-          "integrity": "sha512-QrWXB+ZQSVPmIWIhtEO9H+gwHaMGYiF5ChvoJ+K9ZGHG/sVsa6yiesAD1GC/x46sET00Xlwo1u49RVVVzvcSkw==",
+          "version": "9.5.0",
+          "resolved": "https://registry.npmjs.org/commander/-/commander-9.5.0.tgz",
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-        "rechoir": {
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-          "resolved": "https://registry.npmjs.org/rechoir/-/rechoir-0.7.0.tgz",
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@@ -68969,17 +68946,17 @@
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-      "resolved": "https://registry.npmjs.org/mysql2/-/mysql2-2.3.3.tgz",
-      "integrity": "sha512-wxJUev6LgMSgACDkb/InIFxDprRa6T95+VEoR+xPvtngtccNH2dGjEB/fVZ8yg1gWv1510c9CvXuJHi5zUm0ZA==",
+      "version": "3.9.8",
+      "resolved": "https://registry.npmjs.org/mysql2/-/mysql2-3.9.8.tgz",
+      "integrity": "sha512-+5JKNjPuks1FNMoy9TYpl77f+5frbTklz7eb3XDwbpsERRLEeXiW2PDEkakYF50UuKU2qwfGnyXpKYvukv8mGA==",
       "dev": true,
       "requires": {
-        "denque": "^2.0.1",
+        "denque": "^2.1.0",
         "generate-function": "^2.3.1",
         "iconv-lite": "^0.6.3",
-        "long": "^4.0.0",
-        "lru-cache": "^6.0.0",
-        "named-placeholders": "^1.1.2",
+        "long": "^5.2.1",
+        "lru-cache": "^8.0.0",
+        "named-placeholders": "^1.1.3",
         "seq-queue": "^0.0.5",
         "sqlstring": "^2.3.2"
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@@ -68993,25 +68970,10 @@
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-          "resolved": "https://registry.npmjs.org/long/-/long-4.0.0.tgz",
-          "integrity": "sha512-XsP+KhQif4bjX1kbuSiySJFNAehNxgLb6hPRGJ9QsUr8ajHkuXGdrHmFUTUUXhDwVX2R5bY4JNZEwbUiMhV+MA==",
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-          "dev": true,
-          "requires": {
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-        "yallist": {
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-          "resolved": "https://registry.npmjs.org/yallist/-/yallist-4.0.0.tgz",
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+          "version": "8.0.5",
+          "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-8.0.5.tgz",
+          "integrity": "sha512-MhWWlVnuab1RG5/zMRRcVGXZLCXrZTgfwMikgzCegsPnG62yDQo5JnqKkrK4jO5iKqDAZGItAqN5CtKBCBWRUA==",
           "dev": true
         }
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diff --git a/plugins/node/opentelemetry-instrumentation-knex/package.json b/plugins/node/opentelemetry-instrumentation-knex/package.json
index 88329406fe..89adaa26d3 100644
--- a/plugins/node/opentelemetry-instrumentation-knex/package.json
+++ b/plugins/node/opentelemetry-instrumentation-knex/package.json
@@ -49,7 +49,7 @@
     "@opentelemetry/sdk-trace-node": "^1.8.0",
     "@types/mocha": "7.0.2",
     "@types/node": "18.6.5",
-    "knex": "0.95.9",
+    "knex": "2.4.0",
     "mocha": "7.2.0",
     "nyc": "15.1.0",
     "rimraf": "5.0.5",
diff --git a/plugins/node/opentelemetry-instrumentation-mysql2/package.json b/plugins/node/opentelemetry-instrumentation-mysql2/package.json
index 44e4717803..a7c4490039 100644
--- a/plugins/node/opentelemetry-instrumentation-mysql2/package.json
+++ b/plugins/node/opentelemetry-instrumentation-mysql2/package.json
@@ -52,7 +52,7 @@
     "@types/node": "18.6.5",
     "@types/semver": "7.5.3",
     "mocha": "7.2.0",
-    "mysql2": "2.3.3",
+    "mysql2": "3.9.8",
     "nyc": "15.1.0",
     "rimraf": "5.0.5",
     "semver": "7.5.4",