Some sensograms have negative values after dissociation steps, and the Creoptix software cannot fit the Kd in those cases. When the heuristic is "Binding" and there are negative values after dissociation, we can:
- readjust the data based on the baseline after the last dissociation
OR
- zero all negative values
Eda will check the literature for the best strategy
Some sensograms have negative values after dissociation steps, and the Creoptix software cannot fit the Kd in those cases. When the heuristic is "Binding" and there are negative values after dissociation, we can:
OR
Eda will check the literature for the best strategy