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python/tests/beagle_numba.py

Lines changed: 5 additions & 3 deletions
Original file line numberDiff line numberDiff line change
@@ -537,7 +537,7 @@ def interpolate_allele_probs(
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See 'setFirstAlleleProbs', 'setAlleleProbs', and 'setLastAlleleProbs'
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in 'LSHapBaum.java' in BEAGLE 4.1 source code.
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:param numpy.ndarray sm: Hidden state probability matrix at genotyped positions.
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:param numpy.ndarray state_mat: State probability matrix at genotyped positions.
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:param numpy.ndarray ref_h: Reference haplotypes subsetted to ungenotyped positions.
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:param numpy.ndarray pos_typed: Physical positions of genotyped markers (bp).
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:param numpy.ndarray pos_untyped: Physical positions of ungenotyped markers (bp).
@@ -566,20 +566,22 @@ def interpolate_allele_probs(
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# Threshold based on "the number of subsets in the partition Am of H".
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threshold_Am = np.sum(is_a_in_ref_h)
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_MIN_THRESHOLD = min(0.005, 1 / threshold_Am)
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sum_probs_a_k = np.sum(state_mat[k, is_a_in_ref_h])
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sum_probs_a_kM1 = np.sum(state_mat[k - 1, is_a_in_ref_h])
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if k == 0:
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# See 'setFirstAlleleProbs' in 'LSHapBaum.java'.
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assert w == 1.0, "Weight should be 1.0."
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sum_probs_a_k = np.sum(state_mat[k, is_a_in_ref_h])
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if sum_probs_a_k > _MIN_THRESHOLD:
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probs[i, a] += sum_probs_a_k
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elif k == m:
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# See 'setLastAlleleProbs' in 'LSHapBaum.java'.
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assert w == 0.0, "Weight should be 0.0."
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sum_probs_a_kM1 = np.sum(state_mat[k - 1, is_a_in_ref_h])
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if sum_probs_a_kM1 > _MIN_THRESHOLD:
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probs[i, a] += sum_probs_a_kM1
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else:
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# See 'setAlleleProbs' in 'LSHapBaum.java'.
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sum_probs_a_k = np.sum(state_mat[k, is_a_in_ref_h])
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sum_probs_a_kM1 = np.sum(state_mat[k - 1, is_a_in_ref_h])
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if max(sum_probs_a_k, sum_probs_a_kM1) > _MIN_THRESHOLD:
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probs[i, a] += w * sum_probs_a_kM1
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probs[i, a] += (1 - w) * sum_probs_a_k

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