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Merge pull request #243 from hyanwong/patch-45
Add null model rationale
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simulation_overview.md

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@@ -26,7 +26,7 @@ Add links to papers that illustrate each of the following points
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::::
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Exploration
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: Simulations allow us to explore the influence of various historical scenarios on
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: Simulations allow us to explore the influence of complex historical scenarios on
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observed patterns of genetic variation and inheritance.
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Benchmarking and evaluating methodologies
@@ -39,6 +39,11 @@ Bayesian Computation). This is especially important in studies of complex demogr
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where there are many potential parameters and models, making it impractical to specify
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likelihood functions.
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Compare to expectations
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: It is often useful to compare data to what is expected under a simpler situation
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(e.g. for use as a null model). For instance, comparison to *neutral* simulations
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can be used to identify regions subject to selection.
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There are two major forms of population genetic simulation: **forwards-time**
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and **backwards-time**. In general, forwards-time simulation is detailed and more
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realistic, while backwards-time simulation is fast and efficient.

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