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README.md

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+# Author: Etay Hay, 2011
+
+Models of Neocortical Layer 5b Pyramidal Cells Capturing a Wide Range of  
+Dendritic and Perisomatic Active Properties  
+(Hay et al., *PLoS Computational Biology*, 2011)
+
+NEURON models and model sets corresponding to the paper:
+
+Demo: Either auto-launch from ModelDB or download and extract the archive and compile the mod files (with mknrndll (mswin and mac, or nrnivmodl (linux/unix)) and then start the simulation by the file `init.hoc`.
+
+Once the simulation is started select a button to re-create parts of Figure 4 from the paper. Clicking on the Fig. 4A should create an image like:
+
+![screenshot1.png](./screenshot1.png)
+
+Likewise the Fig 4B, Fig 5A buttons should create images like these:
+
+![screenshot2.png](./screenshot2.png)
+
+![screenshot3.png](./screenshot3.png)
+
+## Additional information:
+
+### folder: models
+
+NEURON code models, shown in various figures
+
+- L5PCbiophys1 - figure 1 (constrained only for BAC firing)  
+- L5PCbiophys2 - figure 2 (constrained only for current step firing)  
+- L5PCbiophys3 - figure 4 (constrained both for BAC and current step firing)  
+- L5PCbiophys4 - figure S5 (AP initiation at the axon)  
+- L5PCtemplate - general cell template  
+
+### folder: simulation code
+
+Simulation code for BAC firing or step current firing.
+
+### folder: model sets
+
+Model sets corresponding to various figures.
+
+- models_errors file: error values matrix (rows: models; columns: objectives)  
+- models_parameters file: parameter values matrix (rows: models; columns: parameters)  
+- objetives file: objective names, each corresponding to a column in models_errors file  
+- genome file: parameter names and search limits, each corresponding to a column in the models_parameters file  
+
+### folder: mechanisms
+
+mod files of the conductance mechanisms used.
+
+### folder: morphologies
+
+The three morphologies used in the paper.
+
+---
+
+20130226 added `critical_frequency.hoc` to simulationcode folder  
+20130330 `critical_frequency.hoc` file updated with a comment regarding a difference between 32 and 64 bit NEURON environments.
+20250620 Converted README to Markdown.