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shiyuzhang0522/README.md

Hi there, I'm Shiyu Zhang (张世雨), Shelley 👋✨

🧬 About Me

PhD student in Clinical Medicine at Xiangya Hospital, Central South University (Department of Dermatology) 🏥
I work on population genetics and multi-omics data analysis, driven by a deep fascination with uncovering how genetic variation shapes complex traits and diseases (especially cancer) 🧠💡


📊 GitHub Activity


🔬 Research Interests

  • 🧬 Germline genetic architecture of complex traits
  • 🧪 Single-cell and multi-omics integration in human disease
  • 🛡️ Tumor–immune interactions & biology underlying immunotherapy response

🛠️ Methods & Tools

  • 🧩 Multi-omics: GWAS · WGS · spatial transcriptomics · metabolomics · proteomics
  • 💻 Computational: R · Python · Bash
  • ☁️ Infrastructure: HPC & cloud-based biobank-scale analysis

📌 Selected Projects

(ordered by timeline ⏳)


🔧 Analytic Pipelines


🎯 Funny Toolbox


🌱 A little more about me

Brave · Energetic · Creative
💥 Obsessed with decoding how genetic variation shapes biology — from molecules to populations

🎬 Favorite movie: Interstellar 🚀
🎵 Favorite singer: Taylor Swift 💖


📫 Contact

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  1. Genetic_Architecture_of_Cutaneous_Melanoma Genetic_Architecture_of_Cutaneous_Melanoma Public

    R 1

  2. Metabolomic.Aging.Score.250k.UKBB Metabolomic.Aging.Score.250k.UKBB Public

    This repository shares the code and weight file to produce the metabolomic aging score in the manuscript "A metabolomic profile of biological aging in 250,341 individuals from the UK Biobank". (htt…

    R 1

  3. Interaction-cvPGS-rvPGS Interaction-cvPGS-rvPGS Public

    Codes used in the study "Interactions between rare and common variant genetic risks in determining telomere length"

    R 2