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CHOPshop_MD

Open Source Repo for Molecular Dynamics Analysis Scripts

This repository contains a collection of scripts for analyzing and visualizing molecular dynamics simulations. These scripts are not intended to work "out of the box" but rather as a starting point for creating your own analysis scripts.

CONTENTS

  • [RMSF analysis]

Measure per-residue RMSF for a simulation. This can be used to determine specific regions of a protein that are undergoing conformational changes. Particularly useful when comparing Wild-Type vs Mutant structures.

  • [RMSD analysis]

Measure the RMSD of a selection of residues over time. This can be used to determine if any significant conformational changes have occurred during a simulation.

  • [Hydrogen bond analysis]

Measure the distance and angle between hydrogen bonds over time. This can be used to determine whether specific residues are forming hydrogen bonds with other residues.

  • [Water bridge detection]

Detect water bridges in a simulation. This can be useful for finding interactions that would otherwise be missed by classical hydrogen bond analysis.

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Open Source Repo for Molecular Dynamics Analysis Scripts

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